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Search Results for " pyruvate "

Targets Recommended: Reactive Oxygen Species Endogenous Metabolite

75

抑制剂 & 化合物

17

天然产物

3

化合物库

32

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L2520	糖代谢化合物库		702 compounds
	702 种糖代谢相关的化合物，可用于高通量和高内涵筛选；
L2501	人内源代谢化合物库 Plus		1283 compounds
	1283种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选。
L2521	糖酵解化合物库		555 compounds
	555 种糖酵解相关的活性化合物，可用于高通量和高内涵筛选

化合物库

糖代谢化合物库

Cat.No: L2520

Compounds: 702

人内源代谢化合物库 Plus

Cat.No: L2501

Compounds: 1283

糖酵解化合物库

Cat.No: L2521

Compounds: 555

Cat. No.	Product Name	Target	Signaling Pathways
T7717	Sodium 2-oxopropanoate Sodium pyruvate,丙酮酸钠	Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB
	Sodium 2-oxopropanoate (Sodium pyruvate) 是 pyruvate 的钠盐形式。pyruvate 是葡萄糖的三碳代谢物，是一种在糖酵解途径中产生的化合物，它是一种能够清除 ROS 的自由基清除剂。
T32221	Isoniazid pyruvate NSC-97221,BRN 0185611,NSC97221,NSC 97221,L 1011	Others	Others
	Isoniazid pyruvate is a metabolite of isoniazid. Isoniazid (Laniazid, Nydrazid), also known as isonicotinylhydrazine (INH), is an organic compound that is the first-line medication in prevention and treatment of tuberculosis.
T76143	Pyruvate oxidase	Others	Others
	Pyruvate oxidase(PoxB) 是一种焦磷酸硫胺素依赖型的氧化酶，可以催化丙酮酸氧化脱羧生成乙酰磷酸、二氧化碳和水。Pyruvate oxidase 是细菌代谢中的一种重要酶，常用于生化研究。
T80060	Pyruvate carboxylase	Endogenous Metabolite	Metabolism
	Pyruvate carboxylase是一种催化反应中丙酮酸与HCO3−和MgATP进行依赖性羧化生成草酰乙酸的含生物素酶。它在调控肝脏糖异生、脂肪细胞脂肪酸合成及胰腺β细胞胰岛素分泌方面，对全身能量平衡发挥关键作用。
T76115	Pyruvate kinase	Others	Others
	Pyruvate kinase 是一种糖酵解酶，催化磷酸烯醇式丙酮酸和 ADP 转化为丙酮酸和 ATP。
T12499	PKR-IN-2	PKM	Metabolism
	PKR-IN-2 是丙酮酸激酶PKR 亚型的激活剂，可用于 PKR 功能相关疾病的研究，包括癌症、糖尿病、肥胖、自身免疫性疾病、良性前列腺增生等。
T60341	Pyruvate Carboxylase-IN-1	Others	Others
	Pyruvate Carboxylase-IN-1 (compound 37) 是一种有效的丙酮酸羧化酶(PC) 抑制剂，对于基于细胞裂解物和基于细胞的 PC 活性，IC50s 分别为 0.204 和 0.104 μM。Pyruvate Carboxylase-IN-1 是毛兰素的天然类似物。Pyruvate Carboxylase-IN-1 抑制 PC 的酶活性，介导人肝细胞癌 (HCC) 的抗癌作用。
T61961	Pyruvate Carboxylase-IN-2	Others	Others
	Pyruvate Carboxylase-IN-2 是毛兰素的天然类似物。Pyruvate Carboxylase-IN-2 (compound 29) 是有效的丙酮酸羧化酶(pyruvate carboxylase) 抑制剂。在基于细胞裂解物和基于细胞的 PC 活性中，Pyruvate Carboxylase-IN-2的 IC50s 分别为 0.065 和 0.097 μM。Pyruvate Carboxylase-IN-2介导人肝细胞癌 (HCC) 的抗癌作用。
T6816	DASA-58	PKM	Metabolism
	DASA58 是一种有效的丙酮酸激酶M2 (PKM2) 活化剂，其中AC90=680 nM，AC50=38 nM。
T4223	Mitapivat PKR-IN-1	PKM	Metabolism
	Mitapivat (PKR-IN-1) 是口服具有活性的变构丙酮酸激酶 (pyruvate kinase) 激活剂，其AC50=20 nM。它在广泛的 PKLR 基因型中增加酶活性、蛋白质稳定性和 ATP 水平。它有潜在的恢复 PK 缺乏的糖酵解途径活性的作用。
T1768	7ACC2	Mitochondrial Metabolism; Monocarboxylate transporter	Membrane transporter/Ion channel; Metabolism
	7ACC2 是单羧酸盐转运蛋白抑制剂，IC50为 11 nM。它还是线粒体丙酮酸转运的有效抑制剂，可抑制乳酸涌入，通过抑制乳酸通量来发挥抗癌作用。
T11765	KPLH1130	Dehydrogenase; PDK	Metabolism; PI3K/Akt/mTOR signaling
	KPLH1130，一种选择性丙酮酸脱氢酶激酶(PDK)抑制剂，在高脂饮食(HFD)喂养的小鼠中提高了糖耐量。KPLH1130 抑制巨噬细胞极化并减轻了炎症反应。
T2447	AZD7545	Dehydrogenase	Metabolism
	AZD7545 是竞争性和选择性的PDHK2抑制剂，能够抑制PDHK1和PDHK2的活性，其IC50值分别为 36.8 nM 和 6.4 nM。
T31976	Glymidine sodium	Others	Others
	Glymidine sodium 是口服有活性的抗糖尿病药物，也是肝脂肪分解的抑制剂。它通过抑制葡萄糖的形成，也对由于内源性脂质动员抑制而导致的丙酮酸氧化升高具有抑制作用。
T22350	JX06	Apoptosis; Dehydrogenase; PDK	Apoptosis; Metabolism; PI3K/Akt/mTOR signaling
	JX06 是一种选择性共价PDK 抑制剂，抑制PDK1,PDK2和PDK3，IC50值分别为 49 nM，101 nM 和 313 nM。它以不可逆的方式与半胱氨酸残基共价结合来抑制PDK1活性，具有抗肿瘤活性。
T17224	VER-246608	Dehydrogenase; PDK	Metabolism; PI3K/Akt/mTOR signaling
	VER-246608 是ATP 竞争性的丙酮酸脱氢酶激酶抑制剂，对PDK-1，PDK-3，PDK-2，和PDK-4的IC50分别为 35 nM，40 nM，84 nM 和 91 nM。
T7214	TEPP-46 ML265	PKM	Metabolism
	TEPP-46 (ML265) 是选择性的丙酮酸激酶 M2 (pyruvate kinase M2; PKM2) 激活剂，AC50=92 nM，对 PKM1，PKL 和 PKR 作用较小或没有作用。
T4170	PKM2-IN-1 PKM2 inhibitor,compound 3k	PKM	Metabolism
	PKM2-IN-1 (compound 3k) 是丙酮酸激酶 M2 (PKM2) 抑制剂，其IC50=2.95 μM。
T2607	MSDC 0160 CAY10415,Mitoglitazone,MSDC0160,MSDC-0160	Others; IGF-1R; Mitochondrial Metabolism	Metabolism; Others; Tyrosine Kinase/Adaptors
	MSDC 0160 (CAY10415) 是一种线粒体丙酮酸载体(MPC) 的调节剂，也是调节噻唑烷二酮的线粒体靶标 (mTOT) 的胰岛素增敏剂。它是一种噻唑烷二酮 (TZD)，具有抗糖尿病和神经保护活性作用。它具有用于阿尔茨海默氏病的潜力。
T12412L	PDK4-IN-1 hydrochloride	Apoptosis; PDK	Apoptosis; PI3K/Akt/mTOR signaling
	PDK4-IN-1 hydrochloride 是一种蒽醌衍生物，对丙酮酸脱氢酶激酶 4有抑制作用，IC50为 84 nM，具有口服活性。它抑制细胞转化和细胞增殖并诱导细胞凋亡。它具有抗过敏，抗糖尿病和抗癌作用。
T9235	GW604714X 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-	Mitochondrial Metabolism	Metabolism
	GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) 是一种高度特异性的线粒体丙酮酸载体抑制剂，Ki<0.1 nM。它是一种线粒体呼吸抑制剂。它也能抑制质膜单羧酸转运体的 L-乳酸转运，但浓度比 MPC 的大 4 个数量级。
T19783	Dehydroabiethylamine NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine,脱氢松香胺	P450; PDK	Metabolism; PI3K/Akt/mTOR signaling
	Dehydroabiethylamine (NSC-2955) 是肝脏 CYP2B 活性的诱导剂。 Dehydroabiethylamine 抑制丙酮酸脱氢酶激酶 (PDK) 和细胞内胆固醇转运，具有抗肿瘤活性。
T5882	3-Bromopyruvic acid Hexokinase II Inhibitor II, 3-BP,3-溴丙酮酸,Bromopyruvic acid	Apoptosis; Hexokinase; Autophagy	Apoptosis; Autophagy; Metabolism
	3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) 是己糖激酶 II 抑制剂，是针对肝癌细胞的一种抗肿瘤剂。
T7460	α-Cyano-4-hydroxycinnamic acid α-Cyano-4-hydroxycinnamic acid(α-CHCA),2-氰基-4-羟基	Monocarboxylate transporter	Membrane transporter/Ion channel
	α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) 是非竞争性单羧酸盐转运蛋白 (MCTs) 抑制剂，可抑制线粒体丙酮酸转运蛋白，Ki 值为 6.3 μM。它可作为基质辅助激光解吸电离-飞行时间质谱 (MALDI-TOF) 分析的基质，可以促进肽离子化。
T69237	Phosphoenol-3-bromopyruvate	Others	Others
	Phosphoenol-3-bromopyruvate is a mechanism-based inhibitor of phosphoenolpyruvate carboxylase from maize
T78351	Phosphoenolpyruvate carboxylase PEPC	Others	Others
	Phosphoenolpyruvate carboxylase (PEPC) 是将磷酸烯醇丙酮酸同碳酸氢盐在 Mg2+ 存在下以不可逆的过程转变成草酰乙酸和无机磷的二氧化碳固定酶。该酶在催化景天酸代谢植物中二氧化碳(CO(2))的初级同化过程中发挥关键作用，并在植物代谢的昼夜模式设定中扮演主要角色。
T0745	Disodium monofluorophosphate Sodium Monofluorophosphate,单氟磷酸钠,NSC248	Phosphatase; PKM; Phosphorylase	Metabolism
	Disodium monofluorophosphate (NSC248) 是丙酮酸激酶和碱性磷酸酶的竞争性抑制剂，它也不可逆地抑制磷酸化酶磷酸酶。
T67900	PKM2 inhibitor G	PKM	Metabolism
	PKM2 inhibitor G是丙酮酸激酶抑制剂。
T15944	M77976	PDK	PI3K/Akt/mTOR signaling
	M77976 是一种选择性 ATP 竞争丙酮酸脱氢酶激酶 PDK4 抑制剂，对 PDK4 有抑制作用，IC50 值为 648 μM。M77976 有用于研究肥胖症和糖尿病。
T60102L	Dimethylaminomicheliolide HCl	PKM	Metabolism
	Dimethylaminomicheliolide HCl 具有潜在的抗炎和抗肿瘤活性，通过靶向丙酮酸激酶 2 （PKM2）和重新连接有氧细胞群来抑制胶质母细胞瘤细胞的增殖。
T4441	UK-5099 UK 5099,PF-1005023,UK5099	Others; Mitochondrial Metabolism	Metabolism; Others
	UK-5099 (PF-1005023) 是一种线粒体丙酮酸转运蛋白 MPC 的抑制剂，通过共价可逆的方式与 MPC2 的 C54 结合来抑制 MPC，有助于丙酮酸通过线粒体内膜的运输。UK-5099 具有抗肿瘤活性。
T1546	Nitazoxanide NSC 697855,硝唑尼特	Others; Influenza Virus; Parasite; Autophagy	Autophagy; Microbiology/Virology; Others
	Nitazoxanide (NSC-697855) 是一种广谱驱虫剂，对感染动物和人类的各种蠕虫、原生动物和肠道细菌都具有作用活性。它在无菌培养中抑制Giardia lamblia 滋养体增殖，IC50为 2.4 μM。它可研究寄生虫性胃肠炎，具有抗病毒特性。
T62758	PKM2 activator 2	PKM	Metabolism
	PKM2 activator 2是一种丙酮酸激酶 M2（PKM2）激活剂，AC 50 值为 66 nM。PKM2 activator 2具有抗肿瘤增殖和缓解沃伯格效应的作用，通过激活 PKM2 使细胞的糖酵解代谢恢复正常。
T38715	MSDC-0602K MSDC-0602K,Azemiglitazone potassium	PPAR	DNA Damage/DNA Repair; Metabolism
	MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). This compound, MSDC-0602K, has potential applications in researching fatty liver conditions, including dysfunctional lipid metabolism, inflammation, and insulin resistance. MSDC-0602K acts as an insulin sensitizer, improving insulinemia and fatty liver disease in mice both ...
T8648	6-AZATHYMINE	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	6-Azathymine 是胸腺嘧啶的 6-氮类似物，是 D-3-氨基异丁酸酯-丙酮酸氨基转移酶抑制剂，具有抗菌和抗病毒活性，可抑制DNA 的生物合成。
T6157	Devimistat CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis; Dehydrogenase; Mitochondrial Metabolism	Apoptosis; Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) 是一种线粒体代谢抑制剂，还是一种lipoic acid 拮抗剂，能阻断线粒体能量代谢，诱导多种癌细胞凋亡。
T15362	FX-11 LDHA Inhibitor FX11	Dehydrogenase	Metabolism
	FX-11 (LDHA Inhibitor FX11) 是一种有效的、选择性的和竞争性的乳酸脱氢酶 A (LDHA) 的特异性抑制剂，对LDHA 的Ki 为 8 μM。FX-11 对PKM2 (丙酮酸激酶 M2)具有激活作用。FX-11 可降低 ATP 水平，诱导氧化应激和ROS 生成，可引起细胞死亡。FX-11 在淋巴瘤和胰腺癌异种移植过程中表现出抗肿瘤活性。
T22336	Galloflavin	Dehydrogenase	Metabolism
	Galloflavin 是乳酸脱氢酶抑制剂。用 Pyruvate 法得到的 Ki 为 5.46 µM (LDH-A) 以及15.06 µM (LDH-B)。它能够阻断 ATP 的生成和糖酵解，从而抑制癌细胞的增殖。
T4103	(L)-Sodium lactate L-乳酸钠,Sodium L-Lactate	Others	Others
	(L)-Sodium lactate (Sodium L-Lactate) 是由乳酸脱氢酶从丙酮酸中产生的。它在无氧糖酵解过程中或增殖活跃的细胞中产生。它在人和动物的血液和肌肉液中少量存在。剧烈运动后，肌肉和血液中的乳酸浓度会增加。它也存在于肝脏、肾脏、胸腺、人羊水以及其他器官和体液中。
T0239	Lonidamine AF1890,氯尼达明,DICA,Diclondazolic Acid	Apoptosis; Hexokinase; Mitochondrial Metabolism	Apoptosis; Metabolism
	Lonidamine (Diclondazolic Acid) 是一种抗肿瘤药物，是己糖激酶、线粒体丙酮酸载体和质膜单羧酸转运蛋白抑制剂，同时也抑制线粒体复合物 II。
T69677	Mitapivat sulfate anhydrous	Others	Others
	Mitapivat sulfate anhydrous is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency.
T29863	Algestone acetonide W3395,W-3395,17α-isopropylidenedioxyprogesterone,algestone 16α,17α-acetonide,W 3395	Others	Others
	Pyruvate algebra stone (W-3395) is progesterone.
T12498	PKR activator 2	Others	Others
	PKR activator 2 is a potent activator of pyruvate kinase-R (PKR).
T69865	Mitapivat sulfate	Others	Others
	Mitapivat sulfate, also known as AG-348 sulfate hydrate, is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency.
T70665	PF-06284674	Others	Others
	PF-06284674 is a cell permeable, potent and selective M2 isoform of pyruvate kinase (PKM2) activator.
T12497	PKR activator 1	Others	Others
	PKR activator 1 is a potent activator of pyruvate kinase-R (PKR).
T70418	TLN-232	Others	Others
	TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.
T75132	PKR activator 4	Others	Others
	PKR activator 4 (example 7A) 是一种高效的丙酮酸激酶 R (pyruvate kinase R (PKR)) 激活剂，展现出研究血液疾病的潜力。
T71867	PKM2 inhibitor 2825-0090	Others	Others
	PKM2 inhibitor 2825-0090 is a Novel pyruvate kinase M2 (PKM2) inhibitor, reducing tumor growth of NSCLC xenografts in vivo.
T12412	PDK4-IN-1	Others	Others
	PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).

化合物

Sodium 2-oxopropanoate

Cat.No: T7717

Synonym: Sodium pyruvate,丙酮酸钠

Target: Reactive Oxygen Species, Endogenous Metabolite

Isoniazid pyruvate

Cat.No: T32221

Synonym: NSC-97221,BRN 0185611,NSC97221,NSC 97221,L 1011

Target: Others

Pyruvate oxidase

Cat.No: T76143

Target: Others

Pyruvate carboxylase

Cat.No: T80060

Target: Endogenous Metabolite

Pyruvate kinase

Cat.No: T76115

Target: Others

Cat.No: T12499

Target: PKM

Pyruvate Carboxylase-IN-1

Cat.No: T60341

Target: Others

Pyruvate Carboxylase-IN-2

Cat.No: T61961

Target: Others

Cat.No: T6816

Target: PKM

Cat.No: T4223

Synonym: PKR-IN-1

Target: PKM

Cat.No: T1768

Target: Mitochondrial Metabolism, Monocarboxylate transporter

Cat.No: T11765

Target: Dehydrogenase, PDK

Cat.No: T2447

Target: Dehydrogenase

Glymidine sodium

Cat.No: T31976

Target: Others

Cat.No: T22350

Target: Apoptosis, Dehydrogenase, PDK

Cat.No: T17224

Target: Dehydrogenase, PDK

Cat.No: T7214

Synonym: ML265

Target: PKM

Cat.No: T4170

Synonym: PKM2 inhibitor,compound 3k

Target: PKM

Cat.No: T2607

Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160

Target: Others, IGF-1R, Mitochondrial Metabolism

PDK4-IN-1 hydrochloride

Cat.No: T12412L

Target: Apoptosis, PDK

Cat.No: T9235

Synonym: 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-

Target: Mitochondrial Metabolism

Dehydroabiethylamine

Cat.No: T19783

Synonym: NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine,脱氢松香胺

Target: P450, PDK

3-Bromopyruvic acid

Cat.No: T5882

Synonym: Hexokinase II Inhibitor II, 3-BP,3-溴丙酮酸,Bromopyruvic acid

Target: Apoptosis, Hexokinase, Autophagy

α-Cyano-4-hydroxycinnamic acid

Cat.No: T7460

Synonym: α-Cyano-4-hydroxycinnamic acid(α-CHCA),2-氰基-4-羟基

Target: Monocarboxylate transporter

Phosphoenol-3-bromopyruvate

Cat.No: T69237

Target: Others

Phosphoenolpyruvate carboxylase

Cat.No: T78351

Synonym: PEPC

Target: Others

Disodium monofluorophosphate

Cat.No: T0745

Synonym: Sodium Monofluorophosphate,单氟磷酸钠,NSC248

Target: Phosphatase, PKM, Phosphorylase

PKM2 inhibitor G

Cat.No: T67900

Target: PKM

Cat.No: T15944

Target: PDK

Dimethylaminomicheliolide HCl

Cat.No: T60102L

Target: PKM

Cat.No: T4441

Synonym: UK 5099,PF-1005023,UK5099

Target: Others, Mitochondrial Metabolism

Cat.No: T1546

Synonym: NSC 697855,硝唑尼特

Target: Others, Influenza Virus, Parasite, Autophagy

PKM2 activator 2

Cat.No: T62758

Target: PKM

Cat.No: T38715

Synonym: MSDC-0602K,Azemiglitazone potassium

Target: PPAR

Cat.No: T8648

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis, Antibacterial

Cat.No: T6157

Synonym: CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism

Cat.No: T15362

Synonym: LDHA Inhibitor FX11

Target: Dehydrogenase

Cat.No: T22336

Target: Dehydrogenase

(L)-Sodium lactate

Cat.No: T4103

Synonym: L-乳酸钠,Sodium L-Lactate

Target: Others

Cat.No: T0239

Synonym: AF1890,氯尼达明,DICA,Diclondazolic Acid

Target: Apoptosis, Hexokinase, Mitochondrial Metabolism

Mitapivat sulfate anhydrous

Cat.No: T69677

Target: Others

Algestone acetonide

Cat.No: T29863

Synonym: W3395,W-3395,17α-isopropylidenedioxyprogesterone,algestone 16α,17α-acetonide,W 3395

Target: Others

PKR activator 2

Cat.No: T12498

Target: Others

Mitapivat sulfate

Cat.No: T69865

Target: Others

Cat.No: T70665

Target: Others

PKR activator 1

Cat.No: T12497

Target: Others

Cat.No: T70418

Target: Others

PKR activator 4

Cat.No: T75132

Target: Others

PKM2 inhibitor 2825-0090

Cat.No: T71867

Target: Others

Cat.No: T12412

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T8030	Ethyl pyruvate	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Ethyl pyruvate 是一种内源性代谢物丙酮酸的衍生物，是一种抗炎剂。
T0809	Dicoumarol Dicumarol,双羟香豆素,双香豆素	Dehydrogenase; NADPH; PDK	Metabolism; PI3K/Akt/mTOR signaling
	Dicoumarol (Dicumarol) 是一种 NAD(P)H: 醌氧化还原酶 1 和PDK1的抑制剂，它们的IC50值分别为 0.37 和 19.42 μM。
T3604	Sodium dichloroacetate Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯	Apoptosis; Dehydrogenase; Reactive Oxygen Species; PDK	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Sodium dichloroacetate (DCA) 是一种肿瘤细胞线粒体中的代谢调节剂，一种丙酮酸脱氢酶激酶 (PDK) 抑制剂。Sodium dichloroacetate 具有抗肿瘤活性，可以降低肿瘤微环境中的乳酸，增加活性氧的产生并促进肿瘤细胞凋亡。
T1125	Shikonin NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid	TNF; NF-κB; Chloride channel; HIV Protease; PKM	Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Shikonin (Anchusa acid) 属于天然产物，是一种 TMEM16A 氯离子通道抑制剂 (IC50=6.5 μM) 和选择性 PKM2 抑制剂。Shikonin 具有抗肿瘤、抗炎和伤口愈合活性。
T4891	Sodium phenylpyruvate 苯丙酮酸钠,Phenylpyruvic acid, sodium salt	Others	Others
	Sodium phenylpyruvate (Phenylpyruvic acid, sodium salt) 是phenylpyruvate decarboxylase 和phenylpyruvate tautomerase 互变异构酶的底物。
T4898	Potassium 1-carboxyvinyl hydrogenphosphate PEP-K,磷酸烯醇丙酮酸单钾盐,Phospho(enol)pyruvic acid monopotassium	Others; Endogenous Metabolite	Metabolism; Others
	Potassium 1-carboxyvinyl hydrogenphosphate (PEP-K) 是内源性代谢产物的一种。
T5213	Acetyl phosphate(lithium potassium) 乙酰磷酸锂钾盐,Lithium potassium acetyl phosphate,Acetylphosphoric acid	Others; Endogenous Metabolite	Metabolism; Others
	Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) 是内源性代谢产物的一种。
T8363	DL-Serine	PKM	Metabolism
	DL-Serine 是 D-丝氨酸和 L-丝氨酸的混合物，是一种基础代谢物。它具有抗病毒作用，能抑制烟草花叶病毒的增殖。
T4929	L-2-Phosphoglyceric acid L-GLYCERATE 3-PHOSPHATE 二钠盐,L-2-Phosphoglyceric acid disodium salt h	Others; Endogenous Metabolite	Metabolism; Others
	L-2-Phosphoglyceric acid (L-2-Phosphoglyceric acid disodium salt) 是内源性代谢产物的一种。
T4811	D-Alanine D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid	Chloride channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	D-Alanine ((R)-Alanine) 是一种GlyR 和PMBA 的弱激动剂，其对GlyR 的EC50=9 mM。
T4838	(S)-Malic acid L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸	Others; Endogenous Metabolite	Metabolism; Others
	(S)-Malic acid ((S)-2-Hydroxysuccinic acid) 是天然存在的二羧酸，是水果酸甜味的来源，常用作食品添加剂。
T19365	Hydroxypyruvic acid 3-Hydroxypyruvic acid,β-Hydroxypyruvic acid	Others	Others
	Hydroxypyruvic acid is an intermediate in the metabolism of glycine, serine, and threonine. It is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase.
T60581	Alkannin	Others	Others
	Alkannin 是一种有效且特异性的肿瘤型丙酮酸激酶-M2 (PKM2) 抑制剂，不抑制 PKM1 和丙酮酸激酶-L (PKL)。Alkannin 是一种潜在的抗癌剂。
T16837	SAICAR	Others	Others
	SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).
TN2181	Sarmentosin	Others	Others
	Sarmentosin significantly lowers the SGPT level of patients suffering from chronic viral hepatitis, and shows a suppressive effect on cell-mediated immune responses in mice. It shows a good effect in lowering serum glutamate-pyruvate transaminase.
T82365	Fulvotomentoside B
	Fulvotomentoside B, 一种可从黄毛乳杆菌中分离的皂苷，对于CCl4、d-gal 和对乙酰氨基酚所致中毒小鼠具有显著的保护作用。在减低血清SGPT和GT水平以及减轻肝脏病理损伤方面表现出突出的效果。
T5141	L-2-Phosphoglyceric acid disodium salt hydrate L-2-Phosphoglyceric acid 二钠盐水合物	Others	Others
	L-2-Phosphoglyceric acid disodium salt hydrate 是一种甘油酸，可作为糖酵解第九步的底物。它被烯醇化酶催化为磷酸烯醇式丙酮酸 (PEP)，这是葡萄糖转化为丙酮酸的倒数第二个步骤。

天然产物

Ethyl pyruvate

Cat.No: T8030

Target: Apoptosis, Antioxidant

Cat.No: T0809

Synonym: Dicumarol,双羟香豆素,双香豆素

Target: Dehydrogenase, NADPH, PDK

Sodium dichloroacetate

Cat.No: T3604

Synonym: Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯

Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK

Cat.No: T1125

Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid

Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM

Sodium phenylpyruvate

Cat.No: T4891

Synonym: 苯丙酮酸钠,Phenylpyruvic acid, sodium salt

Target: Others

Potassium 1-carboxyvinyl hydrogenphosphate

Cat.No: T4898

Synonym: PEP-K,磷酸烯醇丙酮酸单钾盐,Phospho(enol)pyruvic acid monopotassium

Target: Others, Endogenous Metabolite

Acetyl phosphate(lithium potassium)

Cat.No: T5213

Synonym: 乙酰磷酸锂钾盐,Lithium potassium acetyl phosphate,Acetylphosphoric acid

Target: Others, Endogenous Metabolite

Cat.No: T8363

Target: PKM

L-2-Phosphoglyceric acid

Cat.No: T4929

Synonym: L-GLYCERATE 3-PHOSPHATE 二钠盐,L-2-Phosphoglyceric acid disodium salt h

Target: Others, Endogenous Metabolite

Cat.No: T4811

Synonym: D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid

Target: Chloride channel, Endogenous Metabolite

Cat.No: T4838

Synonym: L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸

Target: Others, Endogenous Metabolite

Hydroxypyruvic acid

Cat.No: T19365

Synonym: 3-Hydroxypyruvic acid,β-Hydroxypyruvic acid

Target: Others

Cat.No: T60581

Target: Others

Cat.No: T16837

Target: Others

Cat.No: TN2181

Target: Others

Fulvotomentoside B

Cat.No: T82365

L-2-Phosphoglyceric acid disodium salt hydrate

Cat.No: T5141

Synonym: L-2-Phosphoglyceric acid 二钠盐水合物

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00515	PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO) PPDK,Pyruvate, orthophosphate dikinase,Pyruvate...	Entamoeba histolytica	E. coli
	Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis.
TMPH-00422	Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) ppdK,Pyruvate, orthophosphate dikinase,Pyruvate...	Clostridium symbiosum	E. coli
	Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P22983.
TMPH-02625	DLAT Protein, Mouse, Recombinant (E. coli, His) Dihydrolipoyllysine-residue acetyltransferase component of <...	Mouse	E. coli
	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. DLAT Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 62.8 kDa and the accession number is Q8BMF4.
TMPH-01993	PDHX Protein, Human, Recombinant (His & Myc) Lipoyl-containing pyruvate dehydrogenase complex co...	Human	E. coli
	Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. PDHX Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 55.5 kDa and the accession number is O00330.
TMPY-01100	GPT2 Protein, Rat, Recombinant (His) glutamic pyruvate transaminase (alanine aminotransf...	Rat	Baculovirus Insect Cells
	Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share ...
TMPY-04568	PDK1 Protein, Human, Recombinant (His) pyruvate dehydrogenase kinase, isozyme 1,PDHK1	Human	Baculovirus Insect Cells
	Pyruvate dehydrogenase kinase, isozyme 1, also known as [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial and PDK1, is a member of the PDK / BCKDK protein kinase family. PDK-1 is expressed predominantly in the heart. It contains one histidine kinase domain. Pyruvate dehydrogenase kinase (PDK) isoforms are molecular switches that downregulate the pyruvate dehydrogenase complex (PDC) by reversible phosphorylation in mitochondria. An inhibitory effect of lipoic acid on PDKs would...
TMPH-02469	PDK1 Protein, Mouse, Recombinant (His) Pdk1,Pyruvate dehydrogenase kinase isoform 1,[P...	Mouse	Baculovirus Insect Cells
	PDK1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 48.7 kDa and the accession number is Q8BFP9.
TMPY-01099	GPT Protein, Rat, Recombinant (His) Gpt1,ALAT,glutamic-pyruvate transaminase (alanine a...	Rat	Baculovirus Insect Cells
	Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc...
TMPY-04445	PDK4 Protein, Mouse, Recombinant (His & GST) AV005916,pyruvate dehydrogenase kinase 4	Mouse	Baculovirus Insect Cells
	Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient availability.Pyruvate dehydrogenase kinase 4 (PDK4) mRNA has been reported as an up-regulated gene in the heart and skeletal muscle of carnitine-deficient juvenile visceral steatosis (JVS) mice under fed conditions. PDK4 plays an important role in the inhibition of glucose oxida...
TMPH-03362	PKM2 Protein, Rat, Recombinant (His & Myc) Pkm,Threonine-protein kinase PKM2,Tyrosine-protein kinase PK...	Rat	Baculovirus Insect Cells
	PKM2 Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 61.8 kDa and the accession number is P11980.
TMPH-02871	PKM2 Protein, Mouse, Recombinant (His & Myc) Pkm,Pyruvate kinase muscle isozyme,Pyruvate	Mouse	Baculovirus Insect Cells
	PKM2 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 61.8 kDa and the accession number is P52480.
TMPH-02470	PDK3 Protein, Mouse, Recombinant (His) Pdk3,[Pyruvate dehydrogenase (acetyl-transferring)]...	Mouse	E. coli
	PDK3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is Q922H2.
TMPH-02626	DLAT Protein, Mouse, Recombinant (His) Pyruvate dehydrogenase complex component E2,Dlat,Di...	Mouse	HEK293 Cells
	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
TMPH-03363	PKM2 Protein, Rat, Recombinant (E. coli, His & Myc) Pyruvate kinase PKM,Tyrosine-protein kinase PKM2,	Rat	E. coli
	PKM2 Protein, Rat, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 62.8 kDa and the accession number is P11980.
TMPH-02872	PKM2 Protein, Mouse, Recombinant (E. coli, His & Myc) Pyruvate kinase PKM,Pkm,Threonine-protein kinase PK...	Mouse	E. coli
	PKM2 Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 62.8 kDa and the accession number is P52480.
TMPH-00710	PEP synthase Protein, E. coli, Recombinant (His & SUMO) ppsA,Phosphoenolpyruvate synthase,Pyruvate...	E. coli	E. coli
	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
TMPH-00722	PykF Protein, E. coli, Recombinant (His) Pyruvate kinase I,PK-1,pykF	E. coli	E. coli
	Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis.
TMPY-04465	PKM2 Protein, Human, Recombinant (His) pyruvate kinase, muscle,OIP3,CTHBP,PK3,THBP1,HEL-S-...	Human	E. coli
	PKM2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 59 kDa and the accession number is P14618-1.
TMPH-01992	PDHB Protein, Human, Recombinant (His) Pyruvate dehydrogenase E1 component subunit beta, m...	Human	E. coli
	PDHB Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04765	PKLR Protein, Human, Recombinant (His) PKRL,PKR,RPK,PKL,PK1,pyruvate kinase, liver and RBC	Human	E. coli
	Pyruvate kinase (PKLR) is a critical erythrocyte enzyme that is required for glycolysis and production of ATP. Pyruvate kinase deficiency (PKD) is the most frequent red blood cell enzyme abnormality of the glycolytic pathway and the most common cause of hereditary nonspherocytic hemolytic anemia. Over 250 PKLR-gene mutations have been described, including missense/nonsense, splicing and regulatory mutations, small insertions, small and gross deletions, causing PKD and hemolytic anemia of variabl...
TMPY-04766	PKM2 Protein, Mouse, Recombinant (His) AL024424,AA414905,Pk3,Pk-3,pyruvate kinase, muscle,...	Mouse	Baculovirus Insect Cells
	PKM2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60 kDa and the accession number is P52480-2.
TMPH-01991	PDHA1 Protein, Human, Recombinant (His & Myc) Pyruvate dehydrogenase E1 component subunit alpha, ...	Human	E. coli
	PDHA1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00911	GPT Protein, Human, Recombinant (His) Glutamic--alanine transaminase 1,Glutamate pyruvate...	Human	E. coli
	Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. GPT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.5 kDa and the accession number is P24298.
TMPJ-00955	MDH1 Protein, Human, Recombinant (His) Cytosolic Malate Dehydrogenase,MDH1,MDHA,Diiodophenylpyr...	Human	E. coli
	Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted up...
TMPH-00693	L-lactate dehydrogenase Protein, E. coli O9:H4, Recombinant (His) lldD,L-lactate dehydrogenase	E. coli	E. coli
	Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
TMPH-02686	GLXR Protein, Mouse, Recombinant (His & SUMO) Grhpr,Glyoxylate reductase/hydroxypyruvate reductas...	Mouse	E. coli
	Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
TMPH-00602	MetC Protein, E. coli, Recombinant (His) Cysteine lyase MetC,Beta-cystathionase MetC,metC,Cystathioni...	E. coli	E. coli
	Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine. In addition, under certain growth conditions, exhibits significant alanine racemase coactivity.
TMPJ-00797	LDHB Protein, Human, Recombinant (His) LDH-B,Renal Carcinoma Antigen NY-REN-46,LDH-H,LDH Heart Subu...	Human	E. coli
	L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver....
TMPH-01696	SLC16A4 Protein, Human, Recombinant (His) SLC16A4,Monocarboxylate transporter 5,Solute carrier family ...	Human	E. coli
	Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. SLC16A4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is O15374.
TMPY-04773	TPK1 Protein, Human, Recombinant (His) THMD5,PP20,HTPK1,thiamin pyrophosphokinase 1	Human	E. coli
	Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans.
TMPJ-00724	LDHA Protein, Human, Recombinant (His) LDH-M,Renal Carcinoma Antigen NY-REN-59,Cell Proliferation-I...	Human	E. coli
	L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
TMPY-02288	Glyoxalase II/HAGH Protein, Human, Recombinant (His) HAGH1,GLO2,GLX2,hydroxyacylglutathione hydrolase,GLXII	Human	E. coli
	HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. HAGH belongs to the Metallo-beta-lactamase superfamily. HAGH is widely expressed in the kidney, liver, and other tissues. Diseases associated with HAGH include Hydroxyacyl Glutathio...

重组蛋白

PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO)

Cat.No: TMPH-00515

Species: Entamoeba histolytica

Expression System: E. coli

Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc)

Cat.No: TMPH-00422

Species: Clostridium symbiosum

Expression System: E. coli

DLAT Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02625

Species: Mouse

Expression System: E. coli

PDHX Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01993

Species: Human

Expression System: E. coli

GPT2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-01100

Species: Rat

Expression System: Baculovirus Insect Cells

PDK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04568

Species: Human

Expression System: Baculovirus Insect Cells

PDK1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02469

Species: Mouse

Expression System: Baculovirus Insect Cells

GPT Protein, Rat, Recombinant (His)

Cat.No: TMPY-01099

Species: Rat

Expression System: Baculovirus Insect Cells

PDK4 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04445

Species: Mouse

Expression System: Baculovirus Insect Cells

PKM2 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03362

Species: Rat

Expression System: Baculovirus Insect Cells

PKM2 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02871

Species: Mouse

Expression System: Baculovirus Insect Cells

PDK3 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02470

Species: Mouse

Expression System: E. coli

DLAT Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02626

Species: Mouse

Expression System: HEK293 Cells

PKM2 Protein, Rat, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03363

Species: Rat

Expression System: E. coli

PKM2 Protein, Mouse, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-02872

Species: Mouse

Expression System: E. coli

PEP synthase Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00710

Species: E. coli

Expression System: E. coli

PykF Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00722

Species: E. coli

Expression System: E. coli

PKM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04465

Species: Human

Expression System: E. coli

PDHB Protein, Human, Recombinant (His)

Cat.No: TMPH-01992

Species: Human

Expression System: E. coli

PKLR Protein, Human, Recombinant (His)

Cat.No: TMPY-04765

Species: Human

Expression System: E. coli

PKM2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04766

Species: Mouse

Expression System: Baculovirus Insect Cells

PDHA1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01991

Species: Human

Expression System: E. coli

GPT Protein, Human, Recombinant (His)

Cat.No: TMPH-00911

Species: Human

Expression System: E. coli

MDH1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00955

Species: Human

Expression System: E. coli

L-lactate dehydrogenase Protein, E. coli O9:H4, Recombinant (His)

Cat.No: TMPH-00693

Species: E. coli

Expression System: E. coli

GLXR Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02686

Species: Mouse

Expression System: E. coli

MetC Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00602

Species: E. coli

Expression System: E. coli

LDHB Protein, Human, Recombinant (His)

Cat.No: TMPJ-00797

Species: Human

Expression System: E. coli

SLC16A4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01696

Species: Human

Expression System: E. coli

TPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04773

Species: Human

Expression System: E. coli

LDHA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00724

Species: Human

Expression System: E. coli

Glyoxalase II/HAGH Protein, Human, Recombinant (His)

Cat.No: TMPY-02288

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T71305	Clofibric Acid-d4
	Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxal...

同位素标记化合物

Clofibric Acid-d4

Cat.No: T71305

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