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Search Results for " erythrocytes "

Targets Recommended: Aquaporin

34

抑制剂 & 化合物

6

天然产物

15

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T11014	DFP00173	Aquaporin	Membrane transporter/Ion channel
	DFP00173 是一种aquaporin-3 (AQP3)的选择性抑制剂。它对 AQP3 的选择性高于同源 AQP 亚型 AQP7 和 AQP9。它能够抑制小鼠和人 AQP3，IC50值为 ~0.1-0.4 μM。
T7736	2-Chloroadenosine	Adenosine Receptor	GPCR/G Protein; Neuroscience
	2-Chloroadenosine 是腺苷类似物，可防止大鼠海马缺血细胞长期丢失。它是尿苷内流 (Ki:33 μM) 的竞争性抑制剂，高亲和力与硝基苄基硫肌苷结合 (Ki:0.18 mM)。它是一种人红细胞核苷转运体的转运渗透剂。
T4466	Pitofenone hydrochloride Baralgin Ketone Hydrochloride,Pitophenone hydrochloride,吡托非农盐酸盐	AChE	Neuroscience
	Pitofenone hydrochloride (Pitophenone hydrochloride) 是一种能够抑制乙酰胆碱酯酶活性的解痉化合物，对于来自牛红细胞和电鳗的乙酰胆碱酯酶的Ki 分别为 36 和 45 μM。
T25588	L589-420 L 589-420,L-589-420,L-589 420,L 589 420,L589 420	Others	Others
	L589-420 is a sodium pump inhibitor in human erythrocytes.
T69131	Pitofenone	Others	Others
	Pitofenone is an inhibitor of the acetylcholinesterase activity from bovine erythrocytes and electric eel.
T71806	Tenellin	Others	Others
	Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.
T71422	S6821	Others	Others
	S6821 is a TAS2R8 antagonist. S6821 was not found to be mutagenic or clastogenic in vitro, and did not induce micronuclei in bone marrow polychromatic erythrocytes in vivo.
T36795	Donepezil N-oxide	Others	Others
	Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil . Donepezil N-oxide inhibits cholinesterase (ChE) activity in human erythrocytes in a concentration-dependent manner, exhibiting 45.5% inhibition when used at a concentration of 20 μM.
T82826	Bombolitin IV
	Bombolitin IV为大黄蜂毒液中提取的抗菌肽，具有裂解红细胞与脂质体的能力。
T82829	Bombolitin I
	Bombolitin I为源自大黄蜂毒液的抗菌肽，具有裂解红细胞和脂质体的能力。
T82828	Bombolitin II
	Bombolitin II是一种抗菌肽，源自大黄蜂(Vespa crabro)的毒液，具有溶解红细胞和脂质体的能力。
T82827	Bombolitin III
	Bombolitin III为大黄蜂毒液中提取的抗菌肽，具有裂解红细胞和脂质体的功能。
T36766	Palmitoylcholine (chloride)	Others	Others
	Palmitoylcholine is an acyl choline.1It inhibits protein kinase C activity when used at a concentration of 100 μM.2Palmitoylcholine induces hemolysis in rat erythrocytes.3Plasma levels of palmitoylcholine are decreased in female patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).1 1.Germain, A., Barupal, D.K., Levine, S.M., et al.Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl lipids and steroidsMetabolites10(1)34(2020) 2.Nakadate, T.,...
T83908	DXR Inhibitor 11a (free acid) 1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a	Others	Others
	DXR inhibitor 11a是一种针对P. falciparum 1-脱氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它能够抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。
T39322	Temporin A
	Temporin A, a short alpha-helical antimicrobial peptide derived from the skin of Rana temporaria, exhibits a wide-ranging efficacy against Gram-positive bacteria. It directly interacts with the cell membrane of microorganisms and remains non-toxic to erythrocytes at antimicrobial concentrations. Additionally, Temporin A demonstrates antifungal properties against yeast-like Candida albicans.
T14374	AZD2906	Others	Others
	AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.
T83746	RW2 TFA (RW)2-NH2,Arg-Trp-Arg-Trp-NH2
	RW2是一种抗微生物肽，对E. coli和S. aureus均有活性（IC50s分别为730和210 µM）。同时，RW2还能诱导分离的绵羊红细胞发生溶血。
T83748	RW4 TFA (RW)4-NH2,Arg-Trp-Arg-Trp-Arg-Trp-Arg-Trp-NH2
	RW4为一种抗菌肽，对E. coli和S. aureus具有活性（IC50s分别为9.6和5.1 µM）。RW4同时能诱导分离的绵羊红细胞的溶血作用。
T75582	Naja Melanoleuca Venom	Others	Others
	Naja Melanoleuca Venom (Forest Cobra Venom) 是一种蛇毒，可从 Naja Melanoleuca 获得。Naja Melanoleuca Venom 对人类红细胞具有溶血活性。α-神经毒素可以从 Naja Melanoleuca 毒液中分离出来，并抑制 GABAA 受体功能。
T80882	Val-Gly-Ser-Glu NSC 350591
	Val-Gly-Ser-Glu (NSC 350591) 是一种ECF-A四肽。该化合物能剂量依赖性地提升人类嗜酸性粒细胞的数量，而不影响中性粒细胞的数量，并可与补体包被的绵羊红细胞(EAC3b)形成玫瑰花结。
T83747	RW3 TFA (RW)3-NH2,Arg-Trp-Arg-Trp-Arg-Trp-NH2
	RW3是一种抗微生物肽，对大肠杆菌(E. coli)和金黄色葡萄球菌(S. aureus)具有活性，其半抑制浓度(IC50s)分别为16 µM和8 µM。RW3还能诱导分离的绵羊红细胞溶解。
T83885	DXR Inhibitor 11a sodium 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a	Others	Others
	DXR抑制剂11a是P. falciparum 1-去氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。
T22838	hemagglutinin (332-340) [Influenza A virus]	Others	Others
	Influenza hemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. Influenza hemagglutinin proteins bind to cells w
T35587	Ganglioside GD1a mixture (sodium salt) Ganglioside B1	Others	Others
	Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (T...
T38048	Globotetraosylceramides (porcine RBC)	Others	Others
	Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19. Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways. Levels of globotetraosylceramides ...
T6432	Calpeptin	Apoptosis; Cysteine Protease; Proteasome	Apoptosis; Proteases/Proteasome; Ubiquitination
	Calpeptin 是一种具有细胞穿透性的calpain 抑制剂，也是cathepsin K 抑制剂，其对人血小板 Calpain I 的ID50值为40 nM。
T83853	L-K6L9 TFA
	L-K6L9 是由 L-亮氨酸和 L-赖氨酸的L-异构体组成的溶细胞肽。对LNCaP-CL1 雄激素独立型和22Rv1以及LNCaP雄激素依赖型人类前列腺癌细胞具有细胞毒性（LC50分别为4、4和6 µM），同时也对非癌性NIH3T3小鼠成纤维细胞和OL人类包皮成纤维细胞具有细胞毒性（LC50分别为7和5 µM）。在100 µM的浓度下，引起分离的人类红细胞溶血。
T80252	BMAP-18
	BMAP-18为一抗菌肽，是Cathelicidin肽家族中的成员，为BMAP-27的截短版，具备针对Staphylococcus aureus、Streptococcus uberis和Escherichia coli的快速杀菌作用。相比其亲本BMAP-27，BMAP-18展现出优越的细胞选择性，降低了对人红细胞和中性粒细胞的溶血作用，同时保留其抗菌能力。
T38156	N-Acetyl-DL-penicillamine	Others	Others
	N-Acetyl-DL-penicillamine is a chelating agent.1,2,3It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.1,2N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mi...
T68502	Dibrospidium Free Base	Others	Others
	Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correlate with spirobromine antitumor activity. Spirobromin is superior to prospidin by the power of the anti-inflammatory effect. Spyrobromin can diminish the latent period of the development of tumours in the experimental rats at intraperitoneal administration. At intragastric admini...
T38309	LL-37 amide (trifluoroacetate salt)	Others	Others
	LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. It inhibits growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner and LL-37 expression is induced in A549 epithelial cells, alveolar macrophages, neutrophils, and monocyte-derived macrophages following M. tuberculosis infection. LL-37 binds sheep erythrocytes coated with S. ...
T83698	Cathelicidin-2 (128-153) (chicken) TFA Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)
	Cathelicidin-2 (CATH-2) (128-153) 是一种合成抗菌肽，对应于鸡CATH-2的128至153个氨基酸。该化合物对E. coli、S. aureus、S. enteritidis和B. globigii展示出浓度依赖性的活性。CATH-2 (128-153) (40 µM) 可诱导孤立的鸡红细胞溶解，但对孤立的人外周血单个核细胞(PBMCs)无细胞毒性。它能促进化学因子(C-C-基序)配体2 (CCL2)的产生，并抑制LPS诱导的TNF-α、IL-6、IL-8和IL-10在孤立的人PBMCs中的产生。
T83706	BMAP 28 (bovine) TFA Cathelicidin-5 (132-158),Bovine Myeloid Antimicrobial Peptide 28
	BMAP 28是一种合成抗菌肽，对应牛防御素-5的132-158氨基酸。对大肠杆菌(E. coli)、金黄色葡萄球菌(S. aureus)、耐甲氧西林金黄色葡萄球菌(MRSA)、表皮葡萄球菌(S. epidermidis)及白色念珠菌(C. albicans)具有活性(MICs分别为2、2、4、1和8 µM)。在200 nM浓度下，BMAP 28能够使大肠杆菌的内膜渗透。在5 µM浓度下，减少Vero 76细胞中单纯疱疹病毒1型(HSV-1)的复制。在30 µM浓度下，对分离的人类红细胞引起溶血，并对分离的人类嗜中性粒细胞具有细胞毒性。BMAP 28 (0.8 mg/kg)可提高大肠杆菌或MRSA感染的小鼠的生存率，但对铜绿假单胞菌(P. aeruginosa)感染的小鼠无效。
T83735	Pap12-6 TFA
	Pap12-6是一种从蝶类P. xuthus幼虫中发现的papiliocin十二个N-端氨基酸衍生的抗菌肽。它对包括E. coli、P. aeruginosa和S. syphimurium在内的八种革兰氏阴性细菌（MIC50s = 4-8 µM）以及革兰氏阳性细菌S. aureus、耐甲氧西林的S. aureus 3126（MRSA-3126）、B. subtilis和S. epidermidis（MIC50s = 4-8 µM）具有活性，但在25 µM浓度下不影响人类红细胞、小鼠RAW 264.7巨噬细胞、人类HaCaT角质形成细胞或人类HEK293肾细胞的活性。Pap12-6在4和8 µM浓度下可引起E. coli的膜去极化。Pap12-6（10 µM）预处理可降低LPS刺激的RAW 264.7巨噬细胞中一氧化氮（NO2-）、Tnf-α和Il-6的分泌水平。在体内，Pap12-6（10 mg/kg）可以提高感染E. coli的小鼠的存活率，并且在剂量为1 mg/kg时减少感染E. coli小鼠的肺、肝和肾中菌落形成单位（CFUs）的数量。Pap12-6（1 mg/kg）在E. co...

化合物

Cat.No: T11014

Target: Aquaporin

2-Chloroadenosine

Cat.No: T7736

Target: Adenosine Receptor

Pitofenone hydrochloride

Cat.No: T4466

Synonym: Baralgin Ketone Hydrochloride,Pitophenone hydrochloride,吡托非农盐酸盐

Target: AChE

Cat.No: T25588

Synonym: L 589-420,L-589-420,L-589 420,L 589 420,L589 420

Target: Others

Cat.No: T69131

Target: Others

Cat.No: T71806

Target: Others

Cat.No: T71422

Target: Others

Donepezil N-oxide

Cat.No: T36795

Target: Others

Cat.No: T82826

Cat.No: T82829

Cat.No: T82828

Cat.No: T82827

Palmitoylcholine (chloride)

Cat.No: T36766

Target: Others

DXR Inhibitor 11a (free acid)

Cat.No: T83908

Synonym: 1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a

Target: Others

Cat.No: T39322

Cat.No: T14374

Target: Others

Cat.No: T83746

Synonym: (RW)2-NH2,Arg-Trp-Arg-Trp-NH2

Cat.No: T83748

Synonym: (RW)4-NH2,Arg-Trp-Arg-Trp-Arg-Trp-Arg-Trp-NH2

Naja Melanoleuca Venom

Cat.No: T75582

Target: Others

Val-Gly-Ser-Glu

Cat.No: T80882

Synonym: NSC 350591

Cat.No: T83747

Synonym: (RW)3-NH2,Arg-Trp-Arg-Trp-Arg-Trp-NH2

DXR Inhibitor 11a sodium

Cat.No: T83885

Synonym: 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a

Target: Others

hemagglutinin (332-340) [Influenza A virus]

Cat.No: T22838

Target: Others

Ganglioside GD1a mixture (sodium salt)

Cat.No: T35587

Synonym: Ganglioside B1

Target: Others

Globotetraosylceramides (porcine RBC)

Cat.No: T38048

Target: Others

Cat.No: T6432

Target: Apoptosis, Cysteine Protease, Proteasome

Cat.No: T83853

Cat.No: T80252

N-Acetyl-DL-penicillamine

Cat.No: T38156

Target: Others

Dibrospidium Free Base

Cat.No: T68502

Target: Others

LL-37 amide (trifluoroacetate salt)

Cat.No: T38309

Target: Others

Cathelicidin-2 (128-153) (chicken) TFA

Cat.No: T83698

Synonym: Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)

BMAP 28 (bovine) TFA

Cat.No: T83706

Synonym: Cathelicidin-5 (132-158),Bovine Myeloid Antimicrobial Peptide 28

Cat.No: T83735

Cat. No.	Product Name	Target	Signaling Pathways
T5239	Cholesteryl sulfate sodium Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate	Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) 是内源性代谢产物的一种。
TN1369	Alloimperatorin Prangenidin,别欧前胡素	Others	Others
	Alloimperatorin (Prangenidin) 是一种从Angelica dahurica 的提取得到的香豆素类化合物，具有抗肿瘤作用。
TN3790	Dehydroabietinol Pomiferin A,Dehydroabietyl alcohol	Antifection	Microbiology/Virology
	Dehydroabietinol (Pomiferin A) 在体外抑制红细胞中的氯喹敏感及氯喹抵抗型疟原虫，IC50为26-27 μM.
TN3601	Carminic acid	ROS	Immunology/Inflammation
	Carminic acid 是天然红色色素，是球虫染料家族中的一种。
TN1007	3-Epidehydrotumulosic acid	Others	Others
	3-Epidehydrotumulosic acid exhibits inhibitory effects on AAPH-induced haemolysis of erythrocytes.
TN1728	Hellebrigenin	PARP; Akt; CDK	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Hellebrigenin exhibites moderate to strong activity against human HL-60, SF-295, MDA-MB-435, and HCT-8 cancer cell strains without hemolysis of mouse erythrocytes.

天然产物

Cholesteryl sulfate sodium

Cat.No: T5239

Synonym: Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate

Target: Endogenous Metabolite, PKC

Alloimperatorin

Cat.No: TN1369

Synonym: Prangenidin,别欧前胡素

Target: Others

Dehydroabietinol

Cat.No: TN3790

Synonym: Pomiferin A,Dehydroabietyl alcohol

Target: Antifection

Cat.No: TN3601

Target: ROS

3-Epidehydrotumulosic acid

Cat.No: TN1007

Target: Others

Cat.No: TN1728

Target: PARP, Akt, CDK

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00071	EPO/Erythropoietin Protein, Human, Recombinant (His) Erythropoietin,EPO,红细胞生长素,Epoetin	Human	HEK293 Cells
	Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP...
TMPH-03069	CSL3 Protein, Oncorhynchus keta, Recombinant (His) L-rhamnose-binding lectin CSL3	Oncorhynchus keta	E. coli
	L-rhamnose binding lectin. Has hemagglutinating activity towards rabbit erythrocytes, human type A erythrocytes, human type B erythrocytes, human type O erythrocytes and sheep erythrocytes. Hemagglutinating activity is inhibited by smooth-type lipopolysaccharide (LPS) from S.flexneri 1A, A.salmonicida and E.coli K12, but not by rough-type LPS from S.flexneri, E.coli K12 and E.coli EH100. Agglutinates E.coli K12 and B.subtilis.
TMPK-00558	BCAM Protein, Cynomolgus, Recombinant (His) CD239,MSK19,Lutheran,Gplu,LU	Cynomolgus	HEK293 Cells
	Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
TMPH-03534	Delta-hemolysin Protein, S. aureus, Recombinant (His & KSI) hld,Delta-hemolysin,Delta-toxin,Delta-lysin	Staphylococcus aureus	E. coli
	Lyses erythrocytes and many other mammalian cells. Delta-hemolysin Protein, S. aureus, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.3 kDa and the accession number is P0A0M1.
TMPH-03137	PFS230 Protein, Plasmodium falciparum, Recombinant PFS230,Gametocyte surface protein P230	Plasmodium falciparum	E. coli
	Gametocyte surface protein required for male/female gamete fusion. Also required for male gamete exflagellation and interaction with erythrocytes. PFS230 Protein, Plasmodium falciparum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.9 kDa and the accession number is P68874.
TMPH-00825	Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc) Agglutinin,Mannose-specific lectin,Horcolin	Domesticated barley	E. coli
	Mannose-specific lectin. Has a weak agglutinating activity against rabbit erythrocytes. Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22.6 kDa and the accession number is P82953.
TMPH-02605	Complement C4-B Protein, Mouse, Recombinant (His) C3 and PZP-like alpha-2-macroglobulin domain-containing prot...	Mouse	E. coli
	Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.
TMPH-01432	HMOX1 Protein, Human, Recombinant (His) HMOX1,Heme oxygenase 1	Human	E. coli
	Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. HMOX1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHi...
TMPJ-00902	Kell Protein, Human, Recombinant (His) CD238,KEL,Kell blood group glycoprotein	Human	HEK293 Cells
	Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that car...
TMPJ-00731	Carbonic Anhydrase 1 Protein, Human, Recombinant (His) Carbonic Anhydrase B,Carbonate Dehydratase I,CA-I,Carbonic A...	Human	E. coli
	Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam...
TMPJ-00817	HO-1 Protein, Human, Recombinant HO,HMOX1,HO-1,Heme Oxygenase 1,HO1	Human	E. coli
	Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy me...
TMPJ-00979	GSH-S Protein, Human, Recombinant (His) Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,Glutathione ...	Human	E. coli
	Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon...
TMPJ-00292	CD36 Protein, Human, Recombinant (hFc) FATCHDS7,Glycoprotein IIIb,SCARB3,CD36,Fatty acid translocas...	Human	HEK293 Cells
	Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition rece...
TMPJ-00378	Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His) p90,TfR,T9,Trfr,Transferrin receptor protein 1,TR	Human	HEK293 Cells
	Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o...
TMPY-04391	Lyn Protein, Human, Recombinant (GST) JTK8,LYN proto-oncogene, Src family tyrosine kinase,p56Lyn,p...	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between prolif...

重组蛋白

EPO/Erythropoietin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00071

Species: Human

Expression System: HEK293 Cells

CSL3 Protein, Oncorhynchus keta, Recombinant (His)

Cat.No: TMPH-03069

Species: Oncorhynchus keta

Expression System: E. coli

BCAM Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00558

Species: Cynomolgus

Expression System: HEK293 Cells

Delta-hemolysin Protein, S. aureus, Recombinant (His & KSI)

Cat.No: TMPH-03534

Species: Staphylococcus aureus

Expression System: E. coli

PFS230 Protein, Plasmodium falciparum, Recombinant

Cat.No: TMPH-03137

Species: Plasmodium falciparum

Expression System: E. coli

Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc)

Cat.No: TMPH-00825

Species: Domesticated barley

Expression System: E. coli

Complement C4-B Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02605

Species: Mouse

Expression System: E. coli

HMOX1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01432

Species: Human

Expression System: E. coli

Kell Protein, Human, Recombinant (His)

Cat.No: TMPJ-00902

Species: Human

Expression System: HEK293 Cells

Carbonic Anhydrase 1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00731

Species: Human

Expression System: E. coli

HO-1 Protein, Human, Recombinant

Cat.No: TMPJ-00817

Species: Human

Expression System: E. coli

GSH-S Protein, Human, Recombinant (His)

Cat.No: TMPJ-00979

Species: Human

Expression System: E. coli

CD36 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00292

Species: Human

Expression System: HEK293 Cells

Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)

Cat.No: TMPJ-00378

Species: Human

Expression System: HEK293 Cells

Lyn Protein, Human, Recombinant (GST)

Cat.No: TMPY-04391

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
T71300	Pentoxifylline-d6
	Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 µM. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/...
TMIH-0444	Pitofenone-d4
	Pitofenone-d4 是 Pitofenone 的氘代化合物。Pitofenone 的 CAS 号为 1248-42-6。Pitofenone hydrochloride 是一种能够抑制乙酰胆碱酯酶活性的解痉化合物，对于来自牛红细胞和电鳗的乙酰胆碱酯酶的Ki分别为 36 和 45 μM。
T38356	1,2-Dipalmitoyl-13C-sn-glycero-3-PC
	1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation...

同位素标记化合物

Pentoxifylline-d6

Cat.No: T71300

Cat.No: TMIH-0444

1,2-Dipalmitoyl-13C-sn-glycero-3-PC

Cat.No: T38356

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