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Search Results for " diphosphate "

Targets Recommended: Smo

119

抑制剂 & 化合物

27

天然产物

1

化合物库

35

重组蛋白

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Cat. No.	Product Name
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；

化合物库

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

Cat. No.	Product Name	Target	Signaling Pathways
T15727	Sonidegib diphosphate NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate	Smo	Stem Cells
	Sonidegib diphosphate (LDE225 diphosphate) 是 Smo 的选择性拮抗剂，能够抑制鼠 Smo (IC50:1.3 nM)和人 Smo (IC50:2.5 nM)。
T2691	Oritavancin diphosphate 奥利万星二磷酸盐,LY333328 diphosphate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Oritavancin diphosphate (LY333328 diphosphate) 是一种新型半合成的糖肽抗生素, 可研究革兰氏阳性菌感染。
T31163	Cytidine 5'-diphosphate disodium CDP sodium salt,Cytidine 5'-diphosphate disodium salt,胞苷-5'-二磷酸二钠盐,Cytidine diphosphate sodium salt	Others	Others
	Cytidine 5'-diphosphate disodium (CDP sodium salt) 产生 CTP 以支持 DNA 和 RNA 生物合成和核糖核苷酸还原酶以产生 dCMP。
T2288L	Motesanib Diphosphate Motesanib,AMG 706,二磷酸莫替沙尼	VEGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Motesanib Diphosphate (AMG 706) 是一种有效的VEGFR1/2/3的 ATP 竞争性抑制剂，IC50值为 2 nM/3 nM/6 nM，与对 Kit 的选择性相似，是 PDGFR 和 Ret 的 10 倍多。
T0850	Primaquine diphosphate Primaquine phosphate,磷酸伯氨喹,Primaquine bisphosphate,磷酸伯安喹	Antibiotic; Parasite	Microbiology/Virology
	Primaquine diphosphate 是一种合成的 8-氨基喹啉衍生物，具有抗疟特性。它是一种能破坏间日疟原虫和卵形疟原虫肝脏晚期和潜在组织形态的化合物。
T7606	Guanosine 5'-diphosphate disodium salt 5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐	Endogenous Metabolite	Metabolism
	Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) 是一种核苷二磷酸。它是一种潜在的铁动员剂，能够阻断铁调素-铁转运蛋白相互作用，也可以调节白 IL-6/stat-3 途径。
T13284	Vapendavir diphosphate BTA798 diphosphate	Others	Others
	Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
T20421	Fluorescein diphosphate Fluorescein diphosphate Tetraammonium salt,FDP	Others	Others
	Fluorescein diphosphate is a colorless and nonfluorescent substrate for alkaline phosphatases. The sequential alkaline phosphatase mediated hydrolysis of its two phosphate substituents yielding weakly fluorescent fluorescein monophosphate followed by stro
T78669	(1R,4S)-Yimitasvir diphosphate (1R,4S)-DAG-181 diphosphate,(1R,4S)-Emitasvir diphosphate	Others	Others
	Yimitasvir (Emitasvir) diphosphate是一口服活性HCV NS5A抑制剂，适用于研究慢性丙型肝炎病毒感染。
T37909	Tenofovir diphosphate	Others	Others
	Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and it serves as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1].
T38570	DMAPP triammonium Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt	Others	Others
	DMAPP triammonium (Dimethylallyl diphosphate triammonium) 是一种异戊二烯类化合物的前提物质之一，参与甲羟戊酸 (MVA) 途径，可用于研究与代谢相关的疾病。
T12008	MethADP Adenosine 5'-(α,β-methylene)diphosphate	CD73	Immunology/Inflammation
	MethADP (Adenosine 5'-(α,β-methylene)diphosphate) 是一种特异性的 CD73 抑制剂，抑制 ecto-5′-核苷酸酶（ecto），可用于研究神经系统疾病和心血管疾病。
T36880	NHC-diphosphate	Others	Others
	NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a diphosphate form[1]. NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV)[1]. Huh-7 cells are incubated with (10-50 μM; 4 h) NHC or a McGuigan phosphoramidate prodrug of NHC.Intracellular levels of the parental compounds and ...
T37910	Tenofovir diphosphate triethylamine	Others	Others
	Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive inhibitor of DNA polymerases for dATP, functioning as a substrate for HIV type 1 reverse transcriptase (HIV-1 RT)[1].
T36881	NHC-diphosphate triammonium	Others	Others
	NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. In an intracellular metabolism assay, HCV replicon cells are treated with 10 μM 3H-labeled NHC, and intracellular nucleotide levels are determined after 1, 2 and 8 hours incubations. NHC is rapidly convered into the mono...
T8735	Sulbactum Sodium 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸	Others	Others
	Sulbactum Sodium (5'-CDP) 由胞苷一磷酸 (CMP) 或尿苷一磷酸 (UMP) 通过磷酸基团的转移在尿苷酸激酶 (UMPK) 酶的催化下合成。
T12354L	Oxythiamine diphosphate	Others	Others
	Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).
T29990	Aminoquinol diphosphate	Others	Others
	Aminoquinol diphosphate may be useful in the treatment of acute necrotising cutaneous leishmaniasis.
T37523	Tenofovir diphosphate (sodium salt)	Others	Others
	Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA polymerase α and β, as well as mitochondrial DNA polymerase γ (Kis = 5.2, 81.7, and 59.5 μM, respectively). Tenofovir diphosphate is formed intracellularly through phosphorylation of the prodrugs tenofovir and tenofovir disoproxil by nucleotide kinases. Increased levels of tenof...
T68551	Cabergoline diphosphate	Others	Others
	Cabergoline diphosphate is a dopamine D2 receptor agonist used for prolactinoma treatment. Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
T83813	8-Azidoadenosine-5'-O-diphosphate sodium 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate
	8-Azidoadenosine-5'-O-diphosphate（8-azido-ADP）是ATP前体和嘌呤受体配体ADP的可点击形式。8-azido-ADP的放射性标记形式已被用作各种蛋白质的光亲和标签，包括从牛脑中分离的谷氨酸脱氢酶（GDH）同工酶，以及从兔网织红细胞中分离的真核翻译起始因子2（eIF2）和鸟苷核苷酸交换因子（GEF）。
T37154	7-Methylguanosine 5'-diphosphate sodium	Others	Others
	7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1]. 7-Methylguanosine 5’-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5’-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2]. [1]. Sonenberg N, et al. Nonspecific effect o...
T36740	Guanosine 5’-diphosphate (sodium salt hydrate)	Others	Others
	Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR2B) linked to the inward-rectifier potassium channel 6.1 (Kir6.1) in HEK293T cells in a patch-clamp assay.3 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Biochemistry(2002) 2.Vetter, I.R., and Wittinghofer, A.The guanine nucleotide-binding switch in three dimensionsScience294(5545)...
T71518	Zidovudine diphosphate	Others	Others
	Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
T11001L	Desethyl chloroquine diphosphate	Others	Others
	Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate has anti-plasma activity.
T71609	Hexestrol diphosphate sodium	Others	Others
	Hexestrol diphosphate sodium is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation.
T70251	Hexestrol diphosphate tetrasodium	Others	Others
	Hexestrol diphosphate tetrasodium is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation.
T26648	Arabinose 1,5-diphosphate	Others	Others
	Arabinose 1,5-diphosphate is a bisphosphatase inhibitor.
T72120	Guanosine 5'-diphosphate sodium GDP sodium	Others	Others
	Guanosine 5'-diphosphate (GDP) sodium 是一种核苷二磷酸，可激活 5'-三磷酸腺苷敏感的 K+通道。Guanosine 5'-diphosphate sodium 是一种潜在的铁动员剂，可阻断铁调素-铁转运蛋白 (hepcidin-ferroportin) 相互作用并调节 IL-6/stat-3通路。Guanosine 5'-diphosphate sodium 可用于炎症研究，如炎症性贫血 (AI)。
T32764	Linear-benzoadenosine diphosphate Lin-benzo-ADP	Others	Others
	Linear-benzoadenosine diphosphate is a nucleotide analog.
T83821	Thymidine-5'-O-(α,β-methylene)diphosphate sodium α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP	Others	Others
	TMP-CP（Thymidine-5’-O-(α,β-methylene)diphosphate）是TDP的一种水解稳定衍生物，同时也是一种thymidine kinase抑制剂（Ki = 23 µM）。它已被用作α,β-methylene-2’-deoxythymidine 5’-triphosphate合成的前体，该合成物是DNA polymerase的一种不可切割底物。
T71927	Adenosine-5'-diphosphate disodium salt	Others	Others
	Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
T19579	Thiamine diphosphate analog 1	Others	Others
	Thiamine diphosphate analog 1, an analog of Thiamine diphosphate (the active form of vitamin B1 and a universal cofactor in key cellular pathways), mirrors the structure and potentially the function of its prototype.
T37057	D-myo-Inositol-1,2-diphosphate (sodium salt)	Others	Others
	Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,2)P2 (te...
T37060	D-myo-Inositol-1,3-diphosphate (sodium salt)	Others	Others
	D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in in...
T23581	2-Methylthioadenosine diphosphate trisodium 2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP	Others	Others
	2-MeS-ADP is a purinergic agonist that acts by displaying selectivity for P2Y1, P2Y12, and P2Y13 receptors and inhibiting cAMP accumulation.
T74588	Yimitasvir diphosphate	Others	Others
	Yimitasvir (Emitasvir) diphosphate，一种针对丙型肝炎病毒(HCV)非结构蛋白5A (NS5A)的口服活性抑制剂，适用于慢性丙型肝炎病毒感染的研究。
T36973	5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)	Others	Others
	5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant hormones, alkaloids, and other secondary metabolites from glucose. Several phosphoribosyltransferases (PRTases) use PRPP as a substrate to add a 5-phosphoribosyl group to another substrate, as in the production of adenosine monophosphate from adenine and PRPP by adenine PRTase. N/A
T35572	Adenosine 3',5'-diphosphate sodium salt 3'-Phosphoadenosine 5'-phosphate	Endogenous Metabolite	Metabolism
	Adenosine 3',5'-diphosphate sodium salt 是一种羟类固醇磺基转移酶 (hydroxysteroid sulfotransferases) 抑制剂，是一种腺嘌呤核苷酸，在戊糖核糖的 3'和 5'位置含有一个磷酸基团。Adenosine 3',5'-diphosphate (sodium salt)是 3'-phosphoadenosine 5'-phosphosulfonate (PAPS) 的产物，是磺基转移酶（SULTs）的辅助因子，已被用于研究 SULTs 的动力学特性和结构。
T73807	Geranyl diphosphate	Others	Others
	Geranyl diphosphate 是IBP(类异戊二烯生物合成途径)的关键中间体，在细胞代谢中扮演至关重要的角色，主要负责甾醇和非甾醇类异戊二烯的生成。
T69264	Aristeromycin diphosphate	Others	Others
	Aristeromycin diphosphate is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY), inducing miR-26a and regulating oncogenic EZH2 expression, showing high inhibitory activity against AHCY, and causing growth inhibition of prostate cancer.
T72182	Combretastatin A1 phosphate Oxi4503,CA1P,Oxi4503 ; CA1P ; Combretastatin A1 diphosphate,Combretastatin A1 diphosphate	Others	Others
	Combretastatin A1 phosphate 是一种有效的血管破坏剂。Combretastatin A1 phosphate 对肿瘤具有抗血管生成作用。Combretastatin A1 phosphate 具有用于胰腺神经内分泌肿瘤研究的潜力。
T73983	Cidofovir diphosphate tri(triethylamine)	Others	Others
	Cidofovir diphosphate tri triethylamine 是西多福韦的细胞内活性代谢物。diphosphate tri triethylamine 是病毒 DNA 聚合酶的选择性抑制剂，对 HCMV，HSV-1和 HSV-2的 Ki 值分别为 6.6，0.86 和 1.4 μM。
T64282	Oxythiamine diphosphate ammonium	Others	Others
	Oxythiamin diphosphate ammonium 是一种转酮酶 (TK) 的有效抑制剂。
T78583	Uridine 5'-diphosphate	P2Y Receptor	GPCR/G Protein; Neuroscience
	Uridine 5'-diphosphate 作为P2Y6受体激动剂，具有针对人P2Y6受体0.013 μM的EC50。
T73980	Thymidine 5′-diphosphate	Others	Others
	Thymidine 5′-diphosphate (dTDP) 是合成嘧啶的关键产物，通过胸苷酸激酶 (TMPK) 对 5'-单磷酸胸苷 (dTMP) 进行磷酸化反应生成，此过程需 ATP 与 Mg2+。进一步，dTDP 可被 TMPK 催化转化为胸苷 5'-三磷酸 (dTTP)。通过测量 dTDP 水平，可以评估 TMPK 活性。
T29296	1-Deaza-fad Deazafad,5-Deazariboflavin-5'-diphosphate,1-deazaFAD	Others	Others
	1-Deaza-fad also known as Deazafad. 1-deazaFAD has comparable activity in the mutase reconstituted.
T73899	Uridine diphosphate glucuronic acid ammonium	Others	Others
	Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium 是一种由 UDP-葡萄糖脱氢酶催化生成的辅助因子，属于糖核苷酸生物合成的关键前体。它不仅是 C4 表聚酶和脱羧酶释放 UDP-半乳糖醛酸(UDP-GalA)和 UDP-戊糖产物的共同底物，而且作为葡萄糖醛酸供体，在胆红素在内质直肠结合的研究中有重要应用。
T73824	Thymidine 3',5'-diphosphate tetrasodium	Others	Others
	Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium，为一种选择性抑制剂，主要针对葡萄球菌核酸酶及含1的都铎结构域(SND1，MicroRNA调控复合体RISC亚基)和[3,5-2H2]酪氨酸核酸酶([3,5-2H2] tyrosyl nuclease)。此化合物还展示了抗肿瘤活性，并可在生化反应中作为催化剂使用。
T83817	Isoguanosine-5'-O-diphosphate sodium isoGDP	Others	Others
	Isoguanosine-5'-O-diphosphate (isoGDP)，是GDP的一个异构体，也是crotonoside的一种磷酸化形式。isoGDP能抑制线粒体ATPase（IC50 = 3 µM）。

化合物

Sonidegib diphosphate

Cat.No: T15727

Synonym: NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate

Target: Smo

Oritavancin diphosphate

Cat.No: T2691

Synonym: 奥利万星二磷酸盐,LY333328 diphosphate

Target: Others, Antibacterial, Antibiotic

Cytidine 5'-diphosphate disodium

Cat.No: T31163

Synonym: CDP sodium salt,Cytidine 5'-diphosphate disodium salt,胞苷-5'-二磷酸二钠盐,Cytidine diphosphate sodium salt

Target: Others

Motesanib Diphosphate

Cat.No: T2288L

Synonym: Motesanib,AMG 706,二磷酸莫替沙尼

Target: VEGFR, c-Kit

Primaquine diphosphate

Cat.No: T0850

Synonym: Primaquine phosphate,磷酸伯氨喹,Primaquine bisphosphate,磷酸伯安喹

Target: Antibiotic, Parasite

Guanosine 5'-diphosphate disodium salt

Cat.No: T7606

Synonym: 5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐

Target: Endogenous Metabolite

Vapendavir diphosphate

Cat.No: T13284

Synonym: BTA798 diphosphate

Target: Others

Fluorescein diphosphate

Cat.No: T20421

Synonym: Fluorescein diphosphate Tetraammonium salt,FDP

Target: Others

(1R,4S)-Yimitasvir diphosphate

Cat.No: T78669

Synonym: (1R,4S)-DAG-181 diphosphate,(1R,4S)-Emitasvir diphosphate

Target: Others

Tenofovir diphosphate

Cat.No: T37909

Target: Others

DMAPP triammonium

Cat.No: T38570

Synonym: Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt

Target: Others

Cat.No: T12008

Synonym: Adenosine 5'-(α,β-methylene)diphosphate

Target: CD73

NHC-diphosphate

Cat.No: T36880

Target: Others

Tenofovir diphosphate triethylamine

Cat.No: T37910

Target: Others

NHC-diphosphate triammonium

Cat.No: T36881

Target: Others

Sulbactum Sodium

Cat.No: T8735

Synonym: 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸

Target: Others

Oxythiamine diphosphate

Cat.No: T12354L

Target: Others

Aminoquinol diphosphate

Cat.No: T29990

Target: Others

Tenofovir diphosphate (sodium salt)

Cat.No: T37523

Target: Others

Cabergoline diphosphate

Cat.No: T68551

Target: Others

8-Azidoadenosine-5'-O-diphosphate sodium

Cat.No: T83813

Synonym: 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate

7-Methylguanosine 5'-diphosphate sodium

Cat.No: T37154

Target: Others

Guanosine 5’-diphosphate (sodium salt hydrate)

Cat.No: T36740

Target: Others

Zidovudine diphosphate

Cat.No: T71518

Target: Others

Desethyl chloroquine diphosphate

Cat.No: T11001L

Target: Others

Hexestrol diphosphate sodium

Cat.No: T71609

Target: Others

Hexestrol diphosphate tetrasodium

Cat.No: T70251

Target: Others

Arabinose 1,5-diphosphate

Cat.No: T26648

Target: Others

Guanosine 5'-diphosphate sodium

Cat.No: T72120

Synonym: GDP sodium

Target: Others

Linear-benzoadenosine diphosphate

Cat.No: T32764

Synonym: Lin-benzo-ADP

Target: Others

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

Cat.No: T83821

Synonym: α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP

Target: Others

Adenosine-5'-diphosphate disodium salt

Cat.No: T71927

Target: Others

Thiamine diphosphate analog 1

Cat.No: T19579

Target: Others

D-myo-Inositol-1,2-diphosphate (sodium salt)

Cat.No: T37057

Target: Others

D-myo-Inositol-1,3-diphosphate (sodium salt)

Cat.No: T37060

Target: Others

2-Methylthioadenosine diphosphate trisodium

Cat.No: T23581

Synonym: 2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP

Target: Others

Yimitasvir diphosphate

Cat.No: T74588

Target: Others

5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)

Cat.No: T36973

Target: Others

Adenosine 3',5'-diphosphate sodium salt

Cat.No: T35572

Synonym: 3'-Phosphoadenosine 5'-phosphate

Target: Endogenous Metabolite

Geranyl diphosphate

Cat.No: T73807

Target: Others

Aristeromycin diphosphate

Cat.No: T69264

Target: Others

Combretastatin A1 phosphate

Cat.No: T72182

Synonym: Oxi4503,CA1P,Oxi4503 ; CA1P ; Combretastatin A1 diphosphate,Combretastatin A1 diphosphate

Target: Others

Cidofovir diphosphate tri(triethylamine)

Cat.No: T73983

Target: Others

Oxythiamine diphosphate ammonium

Cat.No: T64282

Target: Others

Uridine 5'-diphosphate

Cat.No: T78583

Target: P2Y Receptor

Thymidine 5′-diphosphate

Cat.No: T73980

Target: Others

Cat.No: T29296

Synonym: Deazafad,5-Deazariboflavin-5'-diphosphate,1-deazaFAD

Target: Others

Uridine diphosphate glucuronic acid ammonium

Cat.No: T73899

Target: Others

Thymidine 3',5'-diphosphate tetrasodium

Cat.No: T73824

Target: Others

Isoguanosine-5'-O-diphosphate sodium

Cat.No: T83817

Synonym: isoGDP

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T1723	Adenosine 5'-diphosphate 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite	Metabolism
	Adenosine 5'-diphosphate (ADP) 是一种嘌呤核糖核苷5'-二磷酸，是 ATP 在 ATP 酶作用下去磷酸化的产物。Adenosine 5'-diphosphate (adenosine pyrophosphate) 可诱导人血小板聚集并通过作用于P2T-嘌呤受体抑制受刺激的腺苷酸环化酶。
T5079	Adenosine 5'-diphosphate sodium salt 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸，是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
T4706	Uridine-5'-diphosphate disodium salt UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐	DNA/RNA Synthesis; Endogenous Metabolite; P2Y Receptor	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Uridine-5'-diphosphate disodium salt (UDP disodium salt) 是一种选择性 P2Y6受体激动剂，EC50为300 nM，对人 P2Y6受体的 pEC50为6.52。它可刺激炎症介质的产生、吞噬作用和血管收缩，催化多种底物的葡糖醛酸糖化反应，用于核酸生物合成。
T7210	Guanosine 5'-diphosphate GDP,鸟苷-5ˊ-二磷酸	Endogenous Metabolite	Metabolism
	Guanosine 5'-diphosphate (GDP) 是核苷二磷酸，是潜在的铁动员剂，能够阻断铁调素-铁转运蛋白相互作用并调节白细胞介素-6 (IL-6)/stat-3 途径。
T4972	2'-Deoxycytidine-5'-diphosphate trisodium dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) 是内源性代谢产物的一种。
T40426	Cytidine 5'-diphosphate trisodium salt CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐	Others	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。
T3228	Fosfructose D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan	Others; Endogenous Metabolite	Metabolism; Others
	D-fructose-1,6-diphosphate 是一种细胞保护性的天然糖磷酸盐，Fosfructose 通过刺激无氧糖酵解起作用，其在缺血条件下产生三磷酸腺苷,有潜力用于心血管缺血，镰状细胞性贫血和哮喘的研究。
T83789	7-Deazaadenosine-5'-O-diphosphate sodium 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP	Others	Others
	7-Deazaadenosine-5'-O-diphosphate是一种修饰过的核苷酸和tubercidin的代谢物。该化合物通过磷酸化tubercidin形成，并进一步磷酸化生成活性代谢物7-deazaadenosine-5'-O-triphosphate。
T0136	Citicoline CDP-Choline,Citicholine,尼古林,cytidine 5'-diphosphocholine,cytidine diphosphate-choline	Apoptosis; Dopamine Receptor; Endogenous Metabolite	Apoptosis; GPCR/G Protein; Metabolism; Neuroscience
	Citicoline (CDP-Choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体，有神经保护作用。
T19599	Uridine diphosphate glucose	Others	Others
	Uridine diphosphate glucose is an important intermediate in several different metabolic pathways and biosynthetic reactions.
T39025	Adenosine 2',5'-diphosphate sodium	Others	Others
	Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist with non-selective antagonism at recombinant and human platelet P2X1 receptors.
T0194	Chloroquine phosphate Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate	SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Chloroquine phosphate (Aralen phosphate) 是广泛用于疟疾和类风湿性关节炎的抗疟疾和抗炎剂。它是autophagy 和toll-like receptors 抑制剂，有效抑制SARS-CoV-2(COVID-19) 感染 (EC50=1.13 μM)。
T6535	Histamine Phosphate 组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Histamine Phosphate (Histamine acid phosphate) 是组胺受体的强激活剂和血管扩张神经剂，可激活一氧化氮合成酶。
T13264	Uridine 5'-diphosphate sodium salt	Others	Others
	Uridine 5'-diphosphate sodium salt is a selective native agonist of the P2Y6 receptor (EC50: 300 nM; pEC50: 6.52), and also is a potent antagonist of P2Y14 (pEC50: 7.28).
T8074	Esafosfan trisodium Fosfructose trisodium,D-果糖-1,6-二磷酸三钠盐,D-Fructose-1,6-diphosphate trisodium salt octahydrate,FDP trisodium,Diphosphofructose trisodium	Others; Endogenous Metabolite	Metabolism; Others
	Esafosfan trisodium (FDP trisodium) 是一种细胞保护性的天然糖磷酸盐，用于镰状细胞性贫血，心血管缺血和哮喘的研究。Fosfructose trisodium 通过刺激无氧糖酵解起作用，其在缺血条件下产生三磷酸腺苷。
T40454	DMAPP Dimethylallyl diphosphate	Others	Others
	DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP).
T80989	Thymidine-5'-diphosphate-L-rhamnose
	Thymidine-5'-diphosphate-L-rhamnose 可从金褐藻 (Occhromonas malhamensis) 提取。
T1208	Citicoline sodium Citicoline sodium salt,CDP-choline,胞磷胆碱钠	Apoptosis; Others; Endogenous Metabolite	Apoptosis; Metabolism; Others
	Citicoline sodium (CDP-choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体，有神经保护作用。
T4713	Phosphorylcholine chloride calcium salt tetrahydrate Phosphocholine chloride calcium salt tet,胆碱磷酸氯化钙四水,CalciuM Phosphorylcholine Tetrahydrate	Others; Endogenous Metabolite	Metabolism; Others
	Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) 是内源性代谢产物的一种。
T1609	NAD+ 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD	NADPH; Endogenous Metabolite	Metabolism
	NAD+ (β-Nicotinamide Adenine Dinucleotide) 是一种转递氢离子的辅酶，参与细胞中的氧化还原反应。NAD+ 参与糖酵解、柠檬酸循环、脂肪酸氧化等。NAD+ 接受来自其他分子的电子形成 NADH，然后又作为还原剂来给电子。
T8047	Menthyl acetate 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate	Others	Others
	Menthyl acetate 是一种可有效增强 5-氨基乙酰丙酸 (ALA) 皮肤渗透的 L-薄荷醇衍生物。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一，抑制溴脱氧尿苷 (Brdu) 的生物效应。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
TN5661	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood.
TN2725	2',5,6',7-Tetrahydroxyflavanone	Others	Others
	(2S)-2',5,6',7-Tetrahydroxyflavanone can inhibit the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
TN1309	6-Hydroxykaempferol-3,6,7-triglucoside	Others	Others
	6-Hydroxykaempferol 3,6,7-tri-O-glucoside and 6-hydroxykaempferol 3,6-di-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation.
TN1310	6-Hydroxykaempferol 3,6-diglucoside	Others	Others
	6-Hydroxykaempferol 3,6-di-O-glucoside and 6-hydroxykaempferol 3,6,7-tri-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation.
TN4664	Norarmepavine	Others	Others
	N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)- N-norarmepavine exhibits significa

天然产物

Adenosine 5'-diphosphate

Cat.No: T1723

Synonym: 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP

Target: Endogenous Metabolite

Adenosine 5'-diphosphate sodium salt

Cat.No: T5079

Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

Uridine-5'-diphosphate disodium salt

Cat.No: T4706

Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐

Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor

Guanosine 5'-diphosphate

Cat.No: T7210

Synonym: GDP,鸟苷-5ˊ-二磷酸

Target: Endogenous Metabolite

2'-Deoxycytidine-5'-diphosphate trisodium

Cat.No: T4972

Synonym: dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐

Target: Endogenous Metabolite

Cytidine 5'-diphosphate trisodium salt

Cat.No: T40426

Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Target: Others

Cat.No: T3228

Synonym: D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan

Target: Others, Endogenous Metabolite

7-Deazaadenosine-5'-O-diphosphate sodium

Cat.No: T83789

Synonym: 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP

Target: Others

Cat.No: T0136

Synonym: CDP-Choline,Citicholine,尼古林,cytidine 5'-diphosphocholine,cytidine diphosphate-choline

Target: Apoptosis, Dopamine Receptor, Endogenous Metabolite

Uridine diphosphate glucose

Cat.No: T19599

Target: Others

Adenosine 2',5'-diphosphate sodium

Cat.No: T39025

Target: Others

Chloroquine phosphate

Cat.No: T0194

Synonym: Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Histamine Phosphate

Cat.No: T6535

Synonym: 组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate

Target: Histamine Receptor

Uridine 5'-diphosphate sodium salt

Cat.No: T13264

Target: Others

Esafosfan trisodium

Cat.No: T8074

Synonym: Fosfructose trisodium,D-果糖-1,6-二磷酸三钠盐,D-Fructose-1,6-diphosphate trisodium salt octahydrate,FDP trisodium,Diphosphofructose trisodium

Target: Others, Endogenous Metabolite

Cat.No: T40454

Synonym: Dimethylallyl diphosphate

Target: Others

Thymidine-5'-diphosphate-L-rhamnose

Cat.No: T80989

Citicoline sodium

Cat.No: T1208

Synonym: Citicoline sodium salt,CDP-choline,胞磷胆碱钠

Target: Apoptosis, Others, Endogenous Metabolite

Phosphorylcholine chloride calcium salt tetrahydrate

Cat.No: T4713

Synonym: Phosphocholine chloride calcium salt tet,胆碱磷酸氯化钙四水,CalciuM Phosphorylcholine Tetrahydrate

Target: Others, Endogenous Metabolite

Cat.No: T1609

Synonym: 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD

Target: NADPH, Endogenous Metabolite

Menthyl acetate

Cat.No: T8047

Synonym: 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate

Target: Others

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one

Cat.No: TN5661

2',5,6',7-Tetrahydroxyflavanone

Cat.No: TN2725

Target: Others

6-Hydroxykaempferol-3,6,7-triglucoside

Cat.No: TN1309

Target: Others

6-Hydroxykaempferol 3,6-diglucoside

Cat.No: TN1310

Target: Others

Cat.No: TN4664

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00099	NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) Nucleoside diphosphate kinase 1,NDK1,Nucleoside	Arabidopsis thaliana	P. pastoris (Yeast)
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a role in response to reactive oxygen species (ROS) stress. NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P39207.
TMPH-01802	NME4 Protein, Human, Recombinant (GST) Nucleoside diphosphate kinase D,Nucleoside diph...	Human	E. coli
	NME4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 44.3 kDa and the accession number is O00746.
TMPY-00477	IDI2 Protein, Human, Recombinant (His) isopentenyl-diphosphate δ isomerase 2,IPPI2,isopent...	Human	E. coli
	IDI2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29 kDa and the accession number is Q9BXS1.
TMPH-03451	NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) YNK1,Nucleoside diphosphate kinase	Saccharomyces cerevisiae	E. coli
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P36010.
TMPH-03452	NDPK Protein, S. cerevisiae, Recombinant (His) Nucleoside diphosphate kinase,YNK1	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is P36010.
TMPH-02137	FDFT1 Protein, Human, Recombinant (His) Squalene synthase,FPP:FPP farnesyltransferase,Farnesyl-d...	Human	E. coli
	FDFT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 52.0 kDa and the accession number is P37268.
TMPY-00451	FDPS Protein, Mouse, Recombinant (His) mKIAA1293,AI256750,farnesyl diphosphate synthase,60...	Mouse	E. coli
	FDPS Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 42.8 kDa and the accession number is Q4FJN9.
TMPY-00330	GGPS1 Protein, Human, Recombinant (His) GGPPS1,geranylgeranyl diphosphate synthase 1,GGPPS	Human	HEK293 Cells
	GGPS1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.3 kDa and the accession number is A0A024R3R2.
TMPH-01323	FDPS Protein, Human, Recombinant (His & SUMO) (2E,6E)-farnesyl diphosphate synthase,Dimethylallyl...	Human	E. coli
	FDPS Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 64.3 kDa and the accession number is P14324.
TMPH-00477	NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5) ndkC-1,ndkC-2,Nucleoside diphosphate kinase, cytoso...	Dictyostelium discoideum	E. coli
	NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5) is expressed in E. coli.
TMPH-01994	GDI2 Protein, Human, Recombinant (His) Rab GDP dissociation inhibitor beta,Guanosine diphosphat...	Human	P. pastoris (Yeast)
	Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. GDI2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 52.7 kDa and the accession number is P50395.
TMPY-00116	MTH1 Protein, Human, Recombinant (His) MTH1,nudix (nucleoside diphosphate linked moiety X)...	Human	E. coli
	NUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1 protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Cancers can survive the oxidative conditions by upregulating nucleoside diphosphate lin...
TMPY-02278	NUDT2 Protein, Human, Recombinant (His) APAH1,nudix (nucleoside diphosphate linked moiety X...	Human	E. coli
	NUDT2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.3 kDa and the accession number is P50583.
TMPH-02964	UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) Cmpk1,UMP-CMP kinase,Nucleoside-diphosphate kinase,...	Mouse	E. coli
	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.2 kDa and the accession number is Q9DBP5.
TMPJ-00937	RRM2 Protein, Human, Recombinant (His) RRM2,RR2,Ribonucleotide Reductase Small Subunit,Ribonucleoti...	Human	HEK293 Cells
	Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the in...
TMPY-03849	NUDT5 Protein, Human, Recombinant (His) hYSAH1,YSAH1,nudix (nucleoside diphosphate linked m...	Human	E. coli
	NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates. ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulates the levels of important signaling nucleotides and their metabolites. It is widely expressed in the liver, skin, and other tissues. NUDT5 functions as a MutT...
TMPY-04467	NME1 Protein, Human, Recombinant (His) NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,...	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...
TMPH-01801	NME2 Protein, Human, Recombinant (His & Myc) NME2,nm23-H2,Histidine protein kinase NDKB,Nucleoside di...	Human	E. coli
	NME2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.2 kDa and the accession number is P22392.
TMPH-02475	OGDC-E Protein, Mouse, Recombinant (His & SUMO) Ogdh,Alpha-ketoglutarate dehydrogenase,Thiamine diphosph...	Mouse	E. coli
	OGDC-E Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 50.8 kDa and the accession number is Q60597.
TMPH-01631	DCP2 Protein, Human, Recombinant (His) m7GpppN-mRNA hydrolase,mRNA-decapping enzyme 2,Nucleoside	Human	E. coli
	DCP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.4 kDa and the accession number is Q8IU60.
TMPH-00850	OGDC-E1 Protein, Human, Recombinant (His & SUMO) OGDH,Alpha-ketoglutarate dehydrogenase,2-oxoglutarate dehydr...	Human	E. coli
	OGDC-E1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.1 kDa and the accession number is Q02218.
TMPY-03287	RRM1 Protein, Human, Recombinant (His & GST) ribonucleotide reductase M1,R1,RR1,RIR1	Human	Baculovirus Insect Cells
	RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. RRM1 is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocort...
TMPH-03585	Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) folP,Dihydropteroate synthase,DHPS,Dihydropteroate pyrophosp...	Staphylococcus haemolyticus	E. coli
	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is Q59919.
TMPH-00589	SpoT Protein, E. coli, Recombinant (His & Myc) Bifunctional (p)ppGpp synthase/hydrolase SpoT,spoT	E. coli	E. coli
	In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes both the synthesis and degradation of ppGpp. The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it. ppGpp activates transcription of CsrA-antagonistic small ...
TMPH-01861	LHPP Protein, Human, Recombinant (His & SUMO) Phospholysine phosphohistidine inorganic pyrophosphate phosp...	Human	E. coli
	Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency. LHPP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.2 kDa and the accession number is Q9H008.
TMPH-02388	pyrE Protein, Laribacter hongkongensis, Recombinant (His & SUMO) Orotate phosphoribosyltransferase,pyrE	Laribacter hongkongensis	E. coli
	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). pyrE Protein, Laribacter hongkongensis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.9 kDa and the accession number is C1D6F5.
TMPY-04767	PMVK Protein, Human, Recombinant (His) PMK,PMKA,phosphomevalonate kinase,HUMPMKI,PMKASE	Human	E. coli
	PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) CMPK,UMPK,UMK,CK,UMP-CMPK,CMK,cytidine monophosphate (UMP-CM...	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid bi...
TMPJ-01262	UPRT Protein, Human, Recombinant (His) UPRT,UPP,FUR1,Uracil phosphoribosyltransferase homolog	Human	E. coli
	UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
TMPJ-00660	IMPase2 Protein, Human, Recombinant (His) Inositol-1(or 4)-Monophosphatase 2,IMPA2,IMP 2,IMPase 2,Inos...	Human	E. coli
	Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphat...
TMPY-04762	CKM Protein, Human, Recombinant (His) creatine kinase, muscle,M-CK,CKMM	Human	E. coli
	CKM, also known as CK-MM, is mainly expressed in skeletal muscle. As the primary CK isoenzyme, it also can be detected in heart muscle. CKM is a subunit of creatine kinase (CK). CK is an enzyme expressed by various tissues and cell types. It catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). In the cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type).
TMPJ-01406	MOB4 Protein, Human, Recombinant (His) PREI3,MOBKL3,Mps One Binder Kinase Activator-Like 3,Mob1 Hom...	Human	E. coli
	MOB-Like Protein Phocein is a member of the MOB1/Phocein Family. MOB-Like Protein Phocein is associated with membranes and the Golgi stacks. It is present in the cytosol, where it behaves as a protein complex. It has been shown that MOB-Like Protein Phocein interacts with DNM1, EPS15 and Nucleoside Diphosphate Kinase. MOB-Like Protein Phocein is the major partner of Striatin Family members and may play a important role in membrane trafficking, specifically in membrane budding reactions.
TMPH-00673	NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His) NAD-capped RNA hydrolase NudC,nudC,NADH pyrophosphatase	E. coli	E. coli
	mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. NADH pyrophosphatase Protein, E. coli O157:H7, Recombina...
TMPJ-00905	DTYMK Protein, Human, Recombinant (His) DTYMK,TMPK,dTMP kinase,Thymidylate kinase,CDC8,TYMK	Human	HEK293 Cells
	Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest ...
TMPJ-01308	ITPase Protein, Human, Recombinant (His) Nucleoside-Triphosphate Diphosphatase,Nucleoside-Triphosphat...	Human	E. coli
	Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation...

重组蛋白

NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Cat.No: TMPH-00099

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

NME4 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01802

Species: Human

Expression System: E. coli

IDI2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00477

Species: Human

Expression System: E. coli

NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)

Cat.No: TMPH-03451

Species: Saccharomyces cerevisiae

Expression System: E. coli

NDPK Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03452

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

FDFT1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02137

Species: Human

Expression System: E. coli

FDPS Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00451

Species: Mouse

Expression System: E. coli

GGPS1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00330

Species: Human

Expression System: HEK293 Cells

FDPS Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01323

Species: Human

Expression System: E. coli

NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5)

Cat.No: TMPH-00477

Species: Dictyostelium discoideum

Expression System: E. coli

GDI2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01994

Species: Human

Expression System: P. pastoris (Yeast)

MTH1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00116

Species: Human

Expression System: E. coli

NUDT2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02278

Species: Human

Expression System: E. coli

UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02964

Species: Mouse

Expression System: E. coli

RRM2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00937

Species: Human

Expression System: HEK293 Cells

NUDT5 Protein, Human, Recombinant (His)

Cat.No: TMPY-03849

Species: Human

Expression System: E. coli

NME1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04467

Species: Human

Expression System: E. coli

NME2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01801

Species: Human

Expression System: E. coli

OGDC-E Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02475

Species: Mouse

Expression System: E. coli

DCP2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01631

Species: Human

Expression System: E. coli

OGDC-E1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00850

Species: Human

Expression System: E. coli

RRM1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03287

Species: Human

Expression System: Baculovirus Insect Cells

Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His)

Cat.No: TMPH-03585

Species: Staphylococcus haemolyticus

Expression System: E. coli

SpoT Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00589

Species: E. coli

Expression System: E. coli

LHPP Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01861

Species: Human

Expression System: E. coli

pyrE Protein, Laribacter hongkongensis, Recombinant (His & SUMO)

Cat.No: TMPH-02388

Species: Laribacter hongkongensis

Expression System: E. coli

PMVK Protein, Human, Recombinant (His)

Cat.No: TMPY-04767

Species: Human

Expression System: E. coli

UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04480

Species: Human

Expression System: Baculovirus Insect Cells

UPRT Protein, Human, Recombinant (His)

Cat.No: TMPJ-01262

Species: Human

Expression System: E. coli

IMPase2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00660

Species: Human

Expression System: E. coli

CKM Protein, Human, Recombinant (His)

Cat.No: TMPY-04762

Species: Human

Expression System: E. coli

MOB4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01406

Species: Human

Expression System: E. coli

NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His)

Cat.No: TMPH-00673

Species: E. coli

Expression System: E. coli

DTYMK Protein, Human, Recombinant (His)

Cat.No: TMPJ-00905

Species: Human

Expression System: HEK293 Cells

ITPase Protein, Human, Recombinant (His)

Cat.No: TMPJ-01308

Species: Human

Expression System: E. coli

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