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Search Results for " analog "

Targets Recommended: Nucleoside Antimetabolite/Analog Others

1325

抑制剂 & 化合物

88

天然产物

4

重组蛋白

28

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T20950	MK-8245 analog MK-8245-analog,MK 8245 analog	Others	Others
	MK-8245 analog 是 MK-8245 的类似物，MK-8245 是一种肝脏靶向的硬脂酰辅酶 A 去饱和酶 (SCD) 抑制剂。它可用于治疗血脂异常和糖尿病。
T9224	CH5424802 analog	ALK	Angiogenesis; Tyrosine Kinase/Adaptors
	CH5424802 analog 是一种选择性 ALK 抑制剂，能够阻断耐药性看门人突变体。
T2518	ARRY-380 (analog ) HER2-Inhibitor-1,ARRY380,ARRY-380 analog	EGFR; HER	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	ARRY-380 analog (HER2-Inhibitor-1) 是EGFR (ErbB1)的抑制剂。
T11070	DO34 analog	Others	Others
	DO34 analog 是二酰基甘油脂肪酶 α (DAGLα) 的抑制剂，DO34 analog 也是 DO34 的一个类似物。
T6921	ONO-4059 analog ONO-4059 analogue,ONO-WG-307,GS-4059 analog	Apoptosis; BTK	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	ONO-4059 analog (ONO-WG-307) 是 ONO-4059 的类似物，ONO-4059 是一种高效、选择性的口服 BTK 抑制剂，IC50 为 23.9 nM。
T12770	RR-11a analog aza-peptide Michael acceptor, 7a	Parasite	Microbiology/Virology
	RR-11a analog (aza-peptide Michael acceptor, 7a) 是一种天冬酰胺酰内肽酶抑制剂，对阴道毛滴虫中的 AE1、蓖麻硬蜱中的 AE 和曼氏血吸虫中的 AE 的 IC50 分别为 4.5 nM、4.5 nM 和 31 nM。
T3076	GLPG0634 analog GLPG0634 analogue	Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	GLPG0634 analog (GLPG0634 analogue) 是一种 JAK 广谱性抑制剂，对 JAK1/JAK2/JAK3 的 IC50值为 50 到 200 nM 之间。
T10858	COH34 analog 1	Others	Others
	COH34 analog 1 是一种 COH34 氧化类似物，可用于合成具有活性的化合物。
T12708	Resveratrol analog 1	Mitophagy; IκB/IKK; Sirtuin; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κB
	Resveratrol analog 1 是天然产物白藜芦醇的类似物，具有比白藜芦醇更显著的抗白血病活性。
T6351	MGCD-265 analog MGCD-265,Glesatinib	Apoptosis; VEGFR; c-Met/HGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	MGCD-265 analog (Glesatinib) 是一种口服生物可利用的多靶点酪氨酸激酶抑制剂，具有抗肿瘤活性，对 c-Met 和 VEGFR2 的 IC50 分别为 29 nM 和 10 nM。
T19004	Hoechst 33258 analog 2	Others	Others
	Hoechst 33258 analog 2是一种 DNA 蓝色荧光染料。
T19005	Hoechst 33258 analog 3	Others	Others
	Hoechst 33258 analog 3 是一种Hoechst 染料，可与DNA 结合，发蓝色荧光。
TP1289	Cardiotoxin Analog (CTX) IV (6-12) TFA Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE)	Others	Others
	Cardiotoxin Analog (CTX) IV (6-12) TFA(115722-23-1 free base) 是 Cardiotoxin Analog (CTX) IV 的部分肽。从台湾眼镜蛇毒液中分离出的心脏毒素类似物 IV。 CTX IV 是一种独特的蛇毒心脏毒素。
T35450	α-GalCer analog 8 α-GalCer analog 8,α-Galactosylceramide analog 8	Others	Others
	α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicati...
T40156	MRTX849 analog 24 MRTX849 analog 24	Others	Others
	MRTX849 analog 24 is an alkyne-containing click probe analogue of the MRTX849 inhibitor for KRAS G12C. It is specifically designed for studying the functionality of MRTX849.
T3558	EBE-A22 PD153035 Analog 63	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EBE-A22 (PD153035 Analog 63) 是 PD153035 衍生物，PD153035 能够抑制 ErbB-1 磷酸化，但对 EBE-A22 则无抑制作用。
T78984	Xanthine oxidase-IN-10 XO8 analog	ROS	Immunology/Inflammation
	Xanthine oxidase-IN-10 (XO8 analog) 是一种黄嘌呤氧化酶 (XO) 抑制剂，可用于研究痛风。
T28919	Tamoxifen analog II Tamoxifen analog III	Others	Others
	Tamoxifen analog II is a potent growth inhibitor. Tamoxifen analog II displays activity against various cancer cell lines.
T19519	Pimelic Diphenylamide 106 analog RGFA-8 analog,TC-H 106 analog	Others	Others
	Pimelic Diphenylamide 106 analog is an Pimelic Diphenylamide 106 analog .
T10629	Btk inhibitor 2 BGB-3111 analog	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	Btk inhibitor 2 (BGB-3111 analog) 是一种布鲁顿酪氨酸激酶 (BTK) 抑制剂。
TQ0230	BTK IN-1 SNS062 analog	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	BTK IN-1 (SNS062 analog) (SNS062 analog) 是一种有效的 BTK 抑制剂 (IC50<100 nM)。
T11256	FAAH inhibitor 1 Benzothiazole analog 3	FAAH	Metabolism; Neuroscience
	FAAH inhibitor 1 (Benzothiazole analog 3) 是一种有效的脂肪酸酰胺水解酶抑制剂，IC50 为 18 nM。
T6266L	PP2 Analog PP2-Analog,CHEMBL-306012,CHEMBL306012,CHEMBL 306012	Others	Others
	PP2 Analog is an analog of PP2. It also acts as a protein trafficking modulator.
T11916	Lyn-IN-1 巴非替尼,Bafetinib analog	Bcr-Abl; Src	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Lyn-IN-1 (Bafetinib analog) 是一种高活性 Bcr-Abl 和 Lyn 双重抑制剂。
T65550	Gefitinib analog III 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate	Others	Others
	Gefitinib analog III (4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate) 具有潜在的抗炎和抗肿瘤活性，可用于研究其在生物体内的相互作用和活性。
T3059	ALK-IN-1 AP26113,Brigatinib,AP26113-analog	EGFR; IGF-1R; ALK	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	ALK-IN-1 (AP26113) 是一种高效的、选择性的 ALK 激酶抑制剂。
T2153	1-NM-PP1 PP1 Analog II,1 nM-PP1	Serine/threonin kinase; CDK; Src	Angiogenesis; Cell Cycle/Checkpoint; Metabolism; Tyrosine Kinase/Adaptors
	1-NM-PP1 (PP1 Analog II) 是一种有效的Src 家族激酶抑制剂，是一种细胞渗透性 PP1 类似物，对 v-Src-as1 与 c-Fyn-as1 的IC50值分别为 4.3 nM、3.2 nM。
T38551	Liproxstatin-1 analog	Others	Others
	Liproxstatin-1 analog is a potent ferroptosis inhibitor, derived from liproxstatin-1 with a similar structure. It effectively inhibits ferroptotic cell death, with an IC50 value of 22 nM.
T16162	Mutated EGFR-IN-1 Osimertinib analog,AZD9291中间体1	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Mutated EGFR-IN-1 (Osimertinib analog) 是用于突变 EGFR 抑制剂设计的有用中间体，例如 L858R EGFR、Exon19 缺失激活突变体和 T790M 抗性突变体。
T39606	CE3F4 analog 1	Others	Others
	CE3F4 analog 1 is an analogue of CE3F4.
T35747	Quinacrine analog 34	Others	Others
	Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 μM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 μM) to inhibit autophagy. At a minimum concentration of 0.5 μM, this compound has been shown to increase the protein levels ...
T69967	Laropiprant analog	Others	Others
	Laropiprant analog is an antagonist of the prostaglandin PGD2 receptor DP1.
T19300	Duocarmycin Analog	DNA Alkylation; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; DNA Damage/DNA Repair
	Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an analog of Duocarmycin.
T38760	Desmethyl-WEHI-345 analog	Others	Others
	Desmethyl-WEHI-345 analog, a protein kinase inhibitor, holds potential for colon cancer research.
T37792	A2A receptor antagonist 1 CPI-444 analog,A2A receptor antagonist 1	Adenosine Receptor	GPCR/G Protein; Neuroscience
	A2A receptor antagonist 1 (CPI-444 analog)是腺苷 A2A 和 A1受体的拮抗剂，Ki 值分别为4和264 nM。
TP1455	Cardiotoxin Analog (CTX) IV (6-12) Cardiotoxin Analog (CTX) IV 6-12
	Cardiotoxin Analog (CTX) IV (6-12) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra.
TP1870	Dermorphin Analog
	Dermorphin Analog is an analog of Dermorphin. Dermorphin is a natural heptapeptide μ-opioid receptor agonist found in amphibian skin. The dermorphin-derived peptide [Dmt1] dermorphin analog labels m-opioid receptors with high affinity and selectivity in r
T39061	Hoechst 33342 analog trihydrochloride	Others	Others
	Hoechst 33342 analog trihydrochloride, an analog of Hoechst 33342, serves as a fluorochrome by binding to the minor groove of DNA, facilitating the visualization of cellular DNA.
T13763	LY88074 analog 1	Others	Others
	LY88074 analog 1, a benzothiophene compound with nitrogen-containing non-basic side chains, can be utilized either independently or alongside estrogen or progestin. This agent is effective for mitigating post-menopausal symptoms, including osteoporosis, cardiovascular-related pathological conditions, and estrogen-dependent cancer.
T12709	Resveratrol analog 2	Others	Others
	Resveratrol analog 2 is an analog of Resveratrol. Resveratrol is a natural polyphenolic phytoalexin with possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.
T19486	Nucleoside-Analog-2	Others	Others
	Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.
T13335	WEHI-345 analog	Others	Others
	WEHI-345 analog is an Src inhibitor.
T19008	Hoechst 33258 analog	Others	Others
	Hoechst 33258 analog are part of a family of blue fluorescent dyes used to stain DNA.
T12258	NSC 601980 (analog)	Others	Others
	NSC 601980 analog is the analog of the NSC601980 which shows antitumor activity in the yeast screening experiment.
T19485	Nucleoside-Analog-1	Others	Others
	Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.
T19272	DB04760 analog 1	Others	Others
	DB04760 analog 1 is an analogue of DB04760.
T8055	TFEB activator 1 (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,(1E,4E)-1,5(2 -甲氧基苯基)-1,4-戊二烯-3-酮,RPN77612	Others; Autophagy	Autophagy; Others
	TFEB activator 1 (Curcumin analog compound C1) 是转录因子 EB 的一种激活剂，有望预防或治疗阿尔茨海默病。
T19010	Hoechst 33342 analog	Others	Others
	Hoechst 33342 analog is an analog of Hoechst 33342 which is a DNA minor groove binder used fluorochrome for visualizing cellular DNA.
T70928	CB-1158-analog	Others	Others
	CB-1158-analog, also known as Numidargistat-analog and INCB01158-analog, is a potent and orally active arginase inhibitor with IC50=89 nM) . CB-1158 blocked myeloid cell-mediated suppression of T cell proliferation in vitro and reduced tumor growth in multiple mouse models of cancer, as a single agent and in combination with checkpoint blockade, adoptive T cell therapy, adoptive NK cell therapy, and the chemotherapy agent gemcitabine. CB-1158 increased tumor-infiltrating CD8+ T cells and NK cell...
T11151	Ecteinascidin-Analog-1	Others	Others
	Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues.

化合物

MK-8245 analog

Cat.No: T20950

Synonym: MK-8245-analog,MK 8245 analog

Target: Others

CH5424802 analog

Cat.No: T9224

Target: ALK

ARRY-380 (analog )

Cat.No: T2518

Synonym: HER2-Inhibitor-1,ARRY380,ARRY-380 analog

Target: EGFR, HER

Cat.No: T11070

Target: Others

ONO-4059 analog

Cat.No: T6921

Synonym: ONO-4059 analogue,ONO-WG-307,GS-4059 analog

Target: Apoptosis, BTK

RR-11a analog

Cat.No: T12770

Synonym: aza-peptide Michael acceptor, 7a

Target: Parasite

GLPG0634 analog

Cat.No: T3076

Synonym: GLPG0634 analogue

Target: Tyrosine Kinases, JAK

COH34 analog 1

Cat.No: T10858

Target: Others

Resveratrol analog 1

Cat.No: T12708

Target: Mitophagy, IκB/IKK, Sirtuin, Autophagy

MGCD-265 analog

Cat.No: T6351

Synonym: MGCD-265,Glesatinib

Target: Apoptosis, VEGFR, c-Met/HGFR

Hoechst 33258 analog 2

Cat.No: T19004

Target: Others

Hoechst 33258 analog 3

Cat.No: T19005

Target: Others

Cardiotoxin Analog (CTX) IV (6-12) TFA

Cat.No: TP1289

Synonym: Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE)

Target: Others

α-GalCer analog 8

Cat.No: T35450

Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8

Target: Others

MRTX849 analog 24

Cat.No: T40156

Synonym: MRTX849 analog 24

Target: Others

Cat.No: T3558

Synonym: PD153035 Analog 63

Target: EGFR

Xanthine oxidase-IN-10

Cat.No: T78984

Synonym: XO8 analog

Target: ROS

Tamoxifen analog II

Cat.No: T28919

Synonym: Tamoxifen analog III

Target: Others

Pimelic Diphenylamide 106 analog

Cat.No: T19519

Synonym: RGFA-8 analog,TC-H 106 analog

Target: Others

Btk inhibitor 2

Cat.No: T10629

Synonym: BGB-3111 analog

Target: BTK

Cat.No: TQ0230

Synonym: SNS062 analog

Target: BTK

FAAH inhibitor 1

Cat.No: T11256

Synonym: Benzothiazole analog 3

Target: FAAH

Cat.No: T6266L

Synonym: PP2-Analog,CHEMBL-306012,CHEMBL306012,CHEMBL 306012

Target: Others

Cat.No: T11916

Synonym: 巴非替尼,Bafetinib analog

Target: Bcr-Abl, Src

Gefitinib analog III

Cat.No: T65550

Synonym: 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Target: Others

Cat.No: T3059

Synonym: AP26113,Brigatinib,AP26113-analog

Target: EGFR, IGF-1R, ALK

Cat.No: T2153

Synonym: PP1 Analog II,1 nM-PP1

Target: Serine/threonin kinase, CDK, Src

Liproxstatin-1 analog

Cat.No: T38551

Target: Others

Mutated EGFR-IN-1

Cat.No: T16162

Synonym: Osimertinib analog,AZD9291中间体1

Target: EGFR

CE3F4 analog 1

Cat.No: T39606

Target: Others

Quinacrine analog 34

Cat.No: T35747

Target: Others

Laropiprant analog

Cat.No: T69967

Target: Others

Duocarmycin Analog

Cat.No: T19300

Target: DNA Alkylation, ADC Cytotoxin

Desmethyl-WEHI-345 analog

Cat.No: T38760

Target: Others

A2A receptor antagonist 1

Cat.No: T37792

Synonym: CPI-444 analog,A2A receptor antagonist 1

Target: Adenosine Receptor

Cardiotoxin Analog (CTX) IV (6-12)

Cat.No: TP1455

Synonym: Cardiotoxin Analog (CTX) IV 6-12

Dermorphin Analog

Cat.No: TP1870

Hoechst 33342 analog trihydrochloride

Cat.No: T39061

Target: Others

LY88074 analog 1

Cat.No: T13763

Target: Others

Resveratrol analog 2

Cat.No: T12709

Target: Others

Nucleoside-Analog-2

Cat.No: T19486

Target: Others

WEHI-345 analog

Cat.No: T13335

Target: Others

Hoechst 33258 analog

Cat.No: T19008

Target: Others

NSC 601980 (analog)

Cat.No: T12258

Target: Others

Nucleoside-Analog-1

Cat.No: T19485

Target: Others

DB04760 analog 1

Cat.No: T19272

Target: Others

TFEB activator 1

Cat.No: T8055

Synonym: (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,(1E,4E)-1,5(2 -甲氧基苯基)-1,4-戊二烯-3-酮,RPN77612

Target: Others, Autophagy

Hoechst 33342 analog

Cat.No: T19010

Target: Others

CB-1158-analog

Cat.No: T70928

Target: Others

Ecteinascidin-Analog-1

Cat.No: T11151

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2S1464	Thiocolchicoside 硫秋水仙苷;噻可撒可,Thiocolchicine 2-glucoside analog,硫秋水仙苷,Coltramyl	Others; GABA Receptor	Membrane transporter/Ion channel; Neuroscience; Others
	Thiocolchicoside (Thiocolchicine 2-glucoside analog) 是秋水仙碱的半合成硫衍生物，是竞争性 GABAA 受体拮抗剂和甘氨酸受体拮抗剂。它是肌肉松弛剂，具有抗炎作用，可用于缓解疼痛的研究。
T3421	Nordihydrocapsaicin	Others	Others
	Nordihydrocapsaicin(诺地氢辣椒碱)是Capsaicin(辣椒素)的模拟物和同源物，属于在Capsicum(辣椒)中发现的Capsaicinoid(辣椒素类)化合物。
T5912	5-Methylcytidine	Endogenous Metabolite	Metabolism
	5-Methylcytidine 是一种位于多种体液中的嘧啶核苷。
T24729	Roseoflavin	Antibacterial	Microbiology/Virology
	Roseoflavin 是天然色素，起初分离自Streptomyces davawensis。Roseoflavin 是核黄素和黄素单核苷酸的抗代谢类似物，显示出抗菌活性。
T7319	7-Methylguanosine	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	7-Methylguanosine 是一种新型 cNIIIB 核苷酸酶抑制剂，IC50值为 87.8 ± 7.5 µM。
T9605	Sangivamycin BA-90912,桑霉素,NSC 65346	Nucleoside Antimetabolite/Analog; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
	Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。
T19382	Isoguanine 2-羟基-6-氨基嘌呤,异鸟嘌呤	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Isoguanine 是一种嘌呤碱基，是鸟嘌呤的异构体，可作为有机合成的砌块。
T7514	N2-Methylguanosine 2-甲鳥苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	N2-Methylguanosine 是一种修饰核苷，出现在许多 tRNA 的几个特定位点。
T7520	Deoxycytidine triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Deoxycytidine triphosphate 是一种核苷三磷酸，是合成 DNA 的原料，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T2217	Cephalomannine Baccatin III,三尖杉宁碱	Microtubule Associated	Cytoskeletal Signaling
	Cephalomannine (Baccatin III) 是一种从云南红豆杉中提取的紫杉醇衍生物，具有抗肿瘤活性，可用于癌症研究。
T16674	Pseudouridine	Endogenous Metabolite	Metabolism
	Pseudouridine 是非编码 RNA 中丰富的修饰核苷，通过稳定 RNA 结构增强核糖体 RNA 和的转移 RNA 功能。
T2221	Uridine Uridin,β-Uridine,NSC 20256,尿苷	Others; Endogenous Metabolite	Metabolism; Others
	Uridine (Uridin) 是一种核苷化合物, 由核糖环和尿嘧啶组成, 两者通过β-N1-配糖键链接。
T0853	Adenosine 腺苷,D-Adenosine,Adenine riboside	Apoptosis; Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenosine (D-Adenosine) 是一种核糖核苷，由与核糖结合的腺嘌呤组成，具有血管扩张、抗心律失常和镇痛作用。
T19083	1-Methylinosine N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	1-Methylinosine (N1-Methylinosine) 是在真核生物 tRNA 反密码子 3' 位 tRNA 的 37 位上发现的修饰核苷酸，具有代谢物的作用。
T0746	Orotic acid 乳清酸,Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog; Dehydrogenase; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Orotic acid (Vitamin B13) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T1591L	Cytidine Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Cytidine (Cytosine-1-β-D-ribofuranoside) 是一种嘧啶核苷，由通过 β-N1-糖苷键与核糖结合的胞嘧啶组成。它是尿苷的前体，用于 RNA 合成。
T2218	8-Azaguanine Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	8-Azaguanine (SK 1150) 是一种具有潜在抗肿瘤活性的嘌呤类似物。它易于掺入核糖核酸中，干扰正常的生物合成途径，从而抑制细胞生长，可作为抗代谢药。
T1508	Decitabine Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA Methyltransferase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Decitabine (Deoxycytidine) 是脱氧胞苷类似物，一种 DNA 甲基转移酶抑制剂，具有口服活性。Decitabine 具有抗肿瘤活性和抗代谢活性。Decitabine 诱导细胞周期阻滞和凋亡。
T1339	5-Azacytidine 阿托胞苷,Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-氮杂胞苷,5-AzaC	Nucleoside Antimetabolite/Analog; DNA Methyltransferase; Antibacterial; Antibiotic; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
	5-Azacytidine (Ladakamycin) 是一种胞苷核苷类似物，一种 DNA 甲基化抑制剂，具有特异性。5-Azacytidine 通过降低 DNA 甲基化水平调节基因表达。5-Azacytidine 可以诱导细胞自噬，具有抗肿瘤活性。
T17143	Toyocamycin 丰加霉素,Vengicide	Apoptosis; Others; IRE1; Antibiotic; Antifungal	Apoptosis; Cell Cycle/Checkpoint; Microbiology/Virology; Others
	Toyocamycin (Vengicide) 是放线菌类产生的腺苷类似物，为 X 盒结合蛋白 1 (XBP1) 抑制剂，抑制 IRE1α 诱导的 ATP 依赖性 XBP1 mRNA 的断裂，IC50值为 80 nM。它还诱导凋亡。
T1272	Cytarabine 阿糖胞苷,Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; HSV	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Cytarabine (Ara-C) 是一种核苷类似物，一种 DNA 合成抑制剂 (IC50=16 nM)。Cytarabine 可以抑制 DNA 聚合酶，诱导细胞周期阻滞、细胞自噬和凋亡。Cytarabine 具有抗肿瘤活性。
T3271	Orotic acid zinc 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Orotic acid zinc (Zinc Orotate) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T1506	Vidarabine Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A	Nucleoside Antimetabolite/Analog; Tyrosine Kinases; DNA/RNA Synthesis; Antibiotic; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Vidarabine (Adenine Arabinoside) 是从链霉菌分离的核苷类抗生素，能抗单纯性疱疹和水痘-带状疱疹病毒。它对 HSV-1 和 HSV-2 的 IC50值分别为 9.3 μg/ml 和 11.3 μg/ml。
T9086	Deoxythymidine-5'-triphosphate trisodium dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate(dTTP) trisodium salt) 是四种天然脱氧核苷酸之一，用于通过 DNA 聚合酶和逆转录酶生物合成脱氧核糖核酸。
T81993	Kadsurin A analogue-1
	Kadsurin A analogue-1 (Compound 8) 为源自Piper argyrophylum的木脂素类化合物。
T0986	Flucytosine 5-Fluorocytosine,Ro 2-9915,5-氟胞嘧啶,Fluorocytosine,NSC 103805	DNA/RNA Synthesis; Antibiotic; Antifungal	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Flucytosine (NSC 103805) 是抗真菌化合物。
TQ0203	Tafluprost MK2452,AFP-168,他氟前列素	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Tafluprost 是一种抗青光眼前列腺素（PG）类似物。
T2197	10-Deacetylbaccatin III 10-脱乙酰巴卡丁 III,10-脱乙酰基巴卡丁III	Others	Others
	10-Deacetylbaccatin-III 是一种紫杉醇类似物制剂的中间体，具有抗癌活性。
T4950	1,2-Dipalmitoyl-sn-glycerol 1,2-双棕榈酸甘油酯,(S)-1,2-Dipalmitin	Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) 是内源性代谢产物的一种。
T9512	Linoleyl alcohol CIS,CIS-9,12-OCTADECADIENOL,亚麻醇	Others	Others
	Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL) 是一种脂肪醇，是一种没有α-羧基的 Linoleic acid 的结构类似物。
T15544	Iberin NSC 321801	Endogenous Metabolite	Metabolism
	Iberin (NSC-321801) 诱导细胞凋亡并抑制细胞存活 (IC50 = 2.3 μM)。 Iberin 是萝卜硫素的类似物。
T2929	Ethyl Vanillate 香兰酸乙酯,Ethylprotal,香草酸乙酯,Bourbonal	Antioxidant; Antifungal	Microbiology/Virology; oxidation-reduction
	Ethyl Vanillate (Bourbonal) 是一种杀菌剂，抑制17β-HSD2，其IC50为 1.3 µM。它是一种香草醛类似物，是一种调味剂，具有很强的抗氧化活性。
TN1017	Physion 8-O-β-D-glucoside 大黄素甲醚-8-o-β-D-葡萄糖苷,Physcion 1-O-beta-D-glucoside	Others	Others
	Physcion 1-O-beta-D-glucoside 是一种 Fallopia multiflora 的活性成分，可用于头晕的研究。
T14149	AICAR phosphate AICA Riboside phosphate,Acadesine phosphate	Mitophagy; NOS; YAP; AMPK	Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Stem Cells
	AICAR phosphate (Acadesine phosphate) 是 AMPK 激活剂且是自噬、YAP 和 mitophagy 抑制剂，也是一种腺苷类似物，可调节糖代谢和脂代谢，抑制促炎细胞因子和 iNOS 的产生。
T5273	2-Hydroxy-3-methylbutanoic acid 2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,2-羟基-3-甲基丁酸,(±)-2-Hydroxyisopentanoic Acid	Others; Endogenous Metabolite	Metabolism; Others
	2-Hydroxy-3-methylbutyric acid 是一种 GHB 的结构类似物，其中GHB 是一种中枢神经系统中发现的天然物质，也是一种神经药物。
T66911	1,3-Dimethoxybenzene Resorcinol dimethyl ether	Others	Others
	1,3-Dimethoxybenzene (Resorcinol dimethyl ether) 是一种来自德国榛子中的二甲氧基苯类化合物，是合成其他化合物的中间体。
T2975	2,3-Dimethoxybenzaldehyde 5,6-Dimethoxybenzaldehyde,邻藜芦醛,o-Veratraldehyde	Antifungal	Microbiology/Virology
	2,3-Dimethoxybenzaldehyde (5,6-Dimethoxybenzaldehyde) 是苯甲酸类似物，具有高抗真菌活性(MIC=2.5 mM)。2,3-Dimethoxybenzaldehyde 可用于合成小檗碱。
T1400	Demeclocycline hydrochloride 地美环素,Declomycin,Clortetrin,盐酸地美环素,Detravis,Demeclocycline HCl	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Demeclocycline hydrochloride (Declomycin) 是四环素类抗生素，可治疗粉刺，莱姆病和支气管炎。
TN2189	Scopoletin acetate 7-Acetoxy-6-methoxycoumari	Antioxidant; Antibacterial	Microbiology/Virology; oxidation-reduction
	Scopoletin acetate (7-Acetoxy-6-methoxycoumari) 是一种从 Artemisia granatensis 提取得到的香豆素类化合物，具有抗氧化、抗菌、心脏保护和抗癌活性，可用于研究癌症和代谢疾病。
T1390	DL-Panthenol Panthenol,DL-泛醇,DL-Pantothenyl alcohol,DL-Pantothenol
	DL-Panthenol (DL-Pantothenyl alcohol) 是一种泛酸的醇类衍生物。它广泛应用于皮肤和毛发护理研究。它具有睫毛保护作用。
T2904	Sclareolide 香紫苏内酯,Norambreinolide	Others; Antibacterial	Microbiology/Virology; Others
	Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物，具有抗菌和细胞毒性作用。
T83321	4-Demethyldeoxypodophyllotoxin	Chk	Cell Cycle/Checkpoint
	4-Demethyldeoxypodophyllotoxin 是一种来自 Podophyllum peltatum 根部的芳基四氢萘木酚素类化合物，具有抗癌活性，可调节 MCF-7乳腺癌细胞中的Chk-2信号通路。
T2481	Ascomycin FK520,Immunomycin,子囊霉素,FR-900520	Phosphatase; Others; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology; Others
	Ascomycin (Immunomycin) 是 Tacrolimus 的乙基类似物，具有免疫抑制特性。它也是一种大环聚酮类抗生素，具有抗疟疾、抗真菌和抗痉挛等多种生物活性。它可防止移植排斥，并具有用于各种皮肤病研究的潜力。
T1238	Daidzein 大豆素,Isoflavone,黄豆苷元	Endogenous Metabolite; PPAR	DNA Damage/DNA Repair; Metabolism
	Daidzein (Isoflavone) 是一种来自大豆的异黄酮提取物，是酪氨酸激酶抑制剂染料木黄酮的无活性类似物，具有抗氧化和植物雌激素特性。
T7927	β-Ionone 乙位紫罗兰酮,β-紫罗兰酮,β-lonone	Apoptosis; Others	Apoptosis; Others
	β-Ionone (β-lonone) 是β-类胡萝卜素的端环类似物，广泛存在于水果和蔬菜中，可有效诱导胃腺癌细胞 SGC7901 凋亡，具有抗增殖、抗转移和抗肿瘤作用。
PDK0101	4-Methylcinnamic acid 对甲基肉桂酸,对甲基肉桂	Antifungal	Microbiology/Virology
	4-Methylcinnamic acid 是一种肉桂酸类似物，可用作克服抗真菌耐受性的干预催化剂。它可提高细胞壁破坏剂的效力。
T0895	Oxytetracycline 土霉素,Terramycin	ribosome; Endogenous Metabolite; Antibacterial; Antibiotic; HSV	Metabolism; Microbiology/Virology
	Oxytetracycline (Terramycin) 是一种四环素类抗生素。它强力抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂，可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合，具有抗 HSV-1的活性。
T3330	trans-Trimethoxyresveratrol trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	trans-Trimethoxyresveratrol (MR-3) 是一种 Resveratrol(RSV) 的衍生物，与Resveratrol(RSV)相比，它可能是一个更有效的抗炎、抗血管新生的化合物。
TN2429	Capsiate	Antioxidant; TRP/TRPV Channel	Membrane transporter/Ion channel; oxidation-reduction
	Capsiate 是一种具有口服活性的 TRPV1 激动剂，是非刺激性辣椒素类似物，可作为抗过敏剂，具有抗炎、抗氧、降糖和抑制血管生成活性。
TQ0298	Fagomine D-Fagomine	ROS; glycosidase	Immunology/Inflammation; Metabolism
	Fagomine (D-Fagomine) 是一种温和的糖苷酶 (glycosidase) 抑制剂，是1-脱氧野尻霉素（DNJ）的类似物，具有降血糖活性，Fagomine 降低了细胞内活性氧（ROS）的产生和丙二醛（MDA）水平。
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天然产物

Thiocolchicoside

Cat.No: T2S1464

Synonym: 硫秋水仙苷;噻可撒可,Thiocolchicine 2-glucoside analog,硫秋水仙苷,Coltramyl

Target: Others, GABA Receptor

Nordihydrocapsaicin

Cat.No: T3421

Target: Others

5-Methylcytidine

Cat.No: T5912

Target: Endogenous Metabolite

Cat.No: T24729

Target: Antibacterial

7-Methylguanosine

Cat.No: T7319

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T9605

Synonym: BA-90912,桑霉素,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

Cat.No: T19382

Synonym: 2-羟基-6-氨基嘌呤,异鸟嘌呤

Target: Nucleoside Antimetabolite/Analog

N2-Methylguanosine

Cat.No: T7514

Synonym: 2-甲鳥苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Deoxycytidine triphosphate

Cat.No: T7520

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T2217

Synonym: Baccatin III,三尖杉宁碱

Target: Microtubule Associated

Cat.No: T16674

Target: Endogenous Metabolite

Cat.No: T2221

Synonym: Uridin,β-Uridine,NSC 20256,尿苷

Target: Others, Endogenous Metabolite

Cat.No: T0853

Synonym: 腺苷,D-Adenosine,Adenine riboside

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy

1-Methylinosine

Cat.No: T19083

Synonym: N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T0746

Synonym: 乳清酸,Vitamin B13,6-Carboxyuracil

Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite

Cat.No: T1591L

Synonym: Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T2218

Synonym: Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

Cat.No: T1508

Synonym: Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase

Cat.No: T1339

Synonym: 阿托胞苷,Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-氮杂胞苷,5-AzaC

Target: Nucleoside Antimetabolite/Analog, DNA Methyltransferase, Antibacterial, Antibiotic, Autophagy

Cat.No: T17143

Synonym: 丰加霉素,Vengicide

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

Cat.No: T1272

Synonym: 阿糖胞苷,Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, HSV

Orotic acid zinc

Cat.No: T3271

Synonym: 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

Cat.No: T1506

Synonym: Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A

Target: Nucleoside Antimetabolite/Analog, Tyrosine Kinases, DNA/RNA Synthesis, Antibiotic, HSV

Deoxythymidine-5'-triphosphate trisodium

Cat.No: T9086

Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

Target: DNA/RNA Synthesis

Kadsurin A analogue-1

Cat.No: T81993

Cat.No: T0986

Synonym: 5-Fluorocytosine,Ro 2-9915,5-氟胞嘧啶,Fluorocytosine,NSC 103805

Target: DNA/RNA Synthesis, Antibiotic, Antifungal

Cat.No: TQ0203

Synonym: MK2452,AFP-168,他氟前列素

Target: Prostaglandin Receptor

10-Deacetylbaccatin III

Cat.No: T2197

Synonym: 10-脱乙酰巴卡丁 III,10-脱乙酰基巴卡丁III

Target: Others

1,2-Dipalmitoyl-sn-glycerol

Cat.No: T4950

Synonym: 1,2-双棕榈酸甘油酯,(S)-1,2-Dipalmitin

Target: Endogenous Metabolite, PKC

Linoleyl alcohol

Cat.No: T9512

Synonym: CIS,CIS-9,12-OCTADECADIENOL,亚麻醇

Target: Others

Cat.No: T15544

Synonym: NSC 321801

Target: Endogenous Metabolite

Ethyl Vanillate

Cat.No: T2929

Synonym: 香兰酸乙酯,Ethylprotal,香草酸乙酯,Bourbonal

Target: Antioxidant, Antifungal

Physion 8-O-β-D-glucoside

Cat.No: TN1017

Synonym: 大黄素甲醚-8-o-β-D-葡萄糖苷,Physcion 1-O-beta-D-glucoside

Target: Others

AICAR phosphate

Cat.No: T14149

Synonym: AICA Riboside phosphate,Acadesine phosphate

Target: Mitophagy, NOS, YAP, AMPK

2-Hydroxy-3-methylbutanoic acid

Cat.No: T5273

Synonym: 2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,2-羟基-3-甲基丁酸,(±)-2-Hydroxyisopentanoic Acid

Target: Others, Endogenous Metabolite

1,3-Dimethoxybenzene

Cat.No: T66911

Synonym: Resorcinol dimethyl ether

Target: Others

2,3-Dimethoxybenzaldehyde

Cat.No: T2975

Synonym: 5,6-Dimethoxybenzaldehyde,邻藜芦醛,o-Veratraldehyde

Target: Antifungal

Demeclocycline hydrochloride

Cat.No: T1400

Synonym: 地美环素,Declomycin,Clortetrin,盐酸地美环素,Detravis,Demeclocycline HCl

Target: ribosome, Antibacterial, Antibiotic

Scopoletin acetate

Cat.No: TN2189

Synonym: 7-Acetoxy-6-methoxycoumari

Target: Antioxidant, Antibacterial

Cat.No: T1390

Synonym: Panthenol,DL-泛醇,DL-Pantothenyl alcohol,DL-Pantothenol

Cat.No: T2904

Synonym: 香紫苏内酯,Norambreinolide

Target: Others, Antibacterial

4-Demethyldeoxypodophyllotoxin

Cat.No: T83321

Target: Chk

Cat.No: T2481

Synonym: FK520,Immunomycin,子囊霉素,FR-900520

Target: Phosphatase, Others, Antibiotic, Parasite, Antifungal

Cat.No: T1238

Synonym: 大豆素,Isoflavone,黄豆苷元

Target: Endogenous Metabolite, PPAR

Cat.No: T7927

Synonym: 乙位紫罗兰酮,β-紫罗兰酮,β-lonone

Target: Apoptosis, Others

4-Methylcinnamic acid

Cat.No: PDK0101

Synonym: 对甲基肉桂酸,对甲基肉桂

Target: Antifungal

Oxytetracycline

Cat.No: T0895

Synonym: 土霉素,Terramycin

Target: ribosome, Endogenous Metabolite, Antibacterial, Antibiotic, HSV

trans-Trimethoxyresveratrol

Cat.No: T3330

Synonym: trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene

Target: Reactive Oxygen Species

Cat.No: TN2429

Target: Antioxidant, TRP/TRPV Channel

Cat.No: TQ0298

Synonym: D-Fagomine

Target: ROS, glycosidase

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03036	Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc) Cardiotoxin 2,CTX A2,Cardiotoxin 1A,Cardiotoxin A2,Cardiotox...	Naja atra	E. coli
	Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities, but 2-fold less important than that of CTX-A4. It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity. It may interact with sulfatides in the cell membrane which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induce mitochondrial swelling and fragmentation.
TMPH-00645	Lactose permease Protein, E. coli, Recombinant (His) Lactose permease,lacY,Lactose-proton symport	E. coli	E. coli
	Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D-galactopyranoside (TMG), but not sucrose or fructose. The substrate specificity is directed toward the galactopyranosyl moiety of the substrate. Lactose permease Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 34.4 kDa...
TMPJ-00871	BAR Protein, S. hygroscopicus, Recombinant bar,PPT N-acetyltransferase,Phosphinothricin-resistance prot...	Streptomyces hygroscopicus	E. coli
	Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant...
TMPH-03038	Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO) Cobra venom factor,Complement C3 homolog,CVFk,CVF	Naja kaouthia	E. coli
	Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re...

重组蛋白

Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)

Cat.No: TMPH-03036

Species: Naja atra

Expression System: E. coli

Lactose permease Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00645

Species: E. coli

Expression System: E. coli

BAR Protein, S. hygroscopicus, Recombinant

Cat.No: TMPJ-00871

Species: Streptomyces hygroscopicus

Expression System: E. coli

Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)

Cat.No: TMPH-03038

Species: Naja kaouthia

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T29867	ALK-001 C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A
	ALK-001 is a vitamin A analog, which may be used to treat Stargardt disease.
T34590	SD-254 Venlafaxine deuterium-substituted,D9-venlafaxine
	SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.
T41001	L-Lactic acid-13C3 L-Lactic acid-13C3,(S)-2-hydroxypropanoic-13-C3
	L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research.
TMIH-0555	Telbivudine-d3
	Telbivudine-d3 是 Telbivudine 的氘代化合物。Telbivudine 的 CAS 号为 3424-98-4。Telbivudine 是一种乙型肝炎病毒复制的抗病毒抑制剂，是一种具有口服活性的胸腺嘧啶核苷类似物。
T11952	Maxacalcitol-D6	Others	Others
	Maxacalcitol-D6 is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.Maxacalcitol-D6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol).
T74145	Deutarserine
	Deutarserine 是内源性 D-丝氨酸 (CTP 692) 的氘代物，用于成人精神分裂症的研究。
TMID-0301	Vitamin-d4-d3
	Vitamin-d4-d3 是 Vitamin 的氘代化合物。Vitamin 的 CAS 号为 511-28-4。
TMID-0300	Vitamin-d4-d5
	Vitamin-d4-d5 是 Vitamin 的氘代化合物。Vitamin 的 CAS 号为 511-28-4。
TMIJ-0034	ent-Thiamphenicol-d3
	ent-Thiamphenicol-d3 是 ent-Thiamphenicol 的氘代化合物。ent-Thiamphenicol 的 CAS 号为 19934-71-5。ent-Thiamphenicol 是抗微生物化合物 Thiamphenicol 的对映体类似物。
TMIH-0335	Methotrexate-d3	ADC Cytotoxin	Antibody-drug Conjugate/ADC Related
	Methotrexate-d3 是 Methotrexate 的氘代化合物。Methotrexate 的 CAS 号为 59-05-2。Methotrexate 是一种叶酸类似物代谢抑制剂，具有免疫抑制剂和抗肿瘤特性，用于类风湿关节炎和研究多种癌症。
TMIJ-0138	Dronedarone-d6 HCl
	Dronedarone-d6 HCl 是 Dronedarone HCl 的氘代化合物。Dronedarone HCl 的 CAS 号为 141625-93-6。Dronedarone Hydrochloride 是一种胺碘酮类似物，可抑制Na+,K+andCa2+的电流，有可能治疗心房颤动。
TMIJ-0029	Sulfadoxine-d4
	Sulfadoxine-d4 是 Sulfadoxine 的氘代化合物。Sulfadoxine 的 CAS 号为 2447-57-6。Sulfadoxine是磺胺类化合物，常与pyrimethamine结合起到抗疟疾作用。它抑制HIV在外周血单核细胞中的复制。
TMIJ-0279	Sulfadoxine-d3
	Sulfadoxine-d3 是 Sulfadoxine 的氘代化合物。Sulfadoxine 的 CAS 号为 2447-57-6。Sulfadoxine是磺胺类化合物，常与pyrimethamine结合起到抗疟疾作用。它抑制HIV在外周血单核细胞中的复制。
T36895	5-Fluorouracil-13C,15N2 5-Fluorouracil-13C,15N2
	5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
TMIJ-0217	Abacavir-d4
	Abacavir-d4 是 Abacavir 的氘代化合物。Abacavir 的 CAS 号为 136470-78-5。Abacavir是一种核苷类似物逆转录酶抑制剂。
TMID-0285	Lamivudine-13C-d2
	Lamivudine-13C-d2 是 Lamivudine 的 13C 和氘代化合物。Lamivudine 的 CAS 号为 134678-17-4。Lamivudine 是一种核苷逆转录酶抑制剂，可抑制HIV逆转录酶1和2 以及乙型肝炎病毒的逆转录酶。
TMIJ-0022	Thiamphenicol-Methyl-d3
	Thiamphenicol-Methyl-d3 是 Thiamphenicol 的氘代化合物。Thiamphenicol 的 CAS 号为 15318-45-3。Thiamphenicol是 Chloramphenicol 的甲基磺酰基衍生物，是一种广谱抗菌类抗生素。它与 50S 核糖体亚基结合，抑制蛋白质合成并具有抑菌作用，特别针对革兰氏阴性，革兰氏阳性需氧和厌氧菌。
TMID-0266	Stavudine-α,α,α,6-d4
	Stavudine-α,α,α,6-d4 是 Stavudine 的氘代化合物。Stavudine 的 CAS 号为 3056-17-5。Stavudine 是一种口服活性核苷逆转录酶抑制剂，还抑制线粒体 DNA 的复制，具有抗HIV-1和HIV-2的活性。它降低 NLRP3 炎症小体激活，调节淀粉样 β 自噬，诱导细胞凋亡。
TMIJ-0306	Ganciclovir-d5
	Ganciclovir-d5 是 Ganciclovir 的氘代化合物。Ganciclovir 的 CAS 号为 82410-32-0。Ganciclovir是核苷类似物和口服抗病毒药物，对CMV具有抗病毒活性。它用于治疗与艾滋病相关的巨细胞病毒感染的并发症。
TMIH-0354	Molnupiravir-d7 EIDD-2801-d7
	Molnupiravir-d7 是 Molnupiravir 的氘代化合物。Molnupiravir 的 CAS 号为 2349386-89-4。EIDD-2801 是核糖核苷类似物 N 4-羟基胞苷 (EIDD-1931) 的异丙酯前药，已显示出广泛的流感病毒和多种冠状病毒活性。
TMIH-0524	Sofosbuvir-13C-d3
	Sofosbuvir-13C-d3 是 Sofosbuvir 的 13C 和氘代化合物。Sofosbuvir 的 CAS 号为 1190307-88-0。Sofosbuvir 是一种丙型肝炎病毒聚合酶 NS5B 的尿苷单磷酸类似物抑制剂，用作治疗慢性丙型肝炎的抗病毒剂。
TMIJ-0193	Hydrocortisone-d4
	Hydrocortisone-d4 是 Hydrocortisone 的氘代化合物。Hydrocortisone 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
TMIJ-0013	Acyclovir-d4
	Acyclovir-d4 是 Acyclovir 的氘代化合物。Acyclovir 的 CAS 号为 59277-89-3。Acyclovir是鸟嘌呤类似物和具有口服活性的抗病毒剂。它对HSV-1(IC50为 0.85 μM)，HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒有活性。
TMID-0229	Cortisol-1,2-d2
	Cortisol-1,2-d2 是 Cortisol 的氘代化合物。Cortisol 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
TMID-0061	MK7-d7
	MK7-d7 是 MK7 的氘代化合物。MK7 的 CAS 号为 2124-57-4。Menaquinone-7 是一种最早作为抗出血因子被发现的维生素K2家族成员。它是Gla-蛋白羧化反应中最具生物活性的辅因子，补充它也是激活Gla基质蛋白并干预钙化性主动脉瓣狭窄(CAVS)进展的一种药理选择。
T38118	Zanamivir-13C,15N2 Zanamivir-13C,15N2
	Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50values ranging from 0.6 to 7.9 nMin vitro. Intra...
TMID-0041	Menaquinone-9-d7 Vitamin K2-MK9-d7
	Menaquinone-9-d7 是 Menaquinone-9 的氘代化合物。Menaquinone-9 的 CAS 号为 523-39-7。Menaquinone 9 (MK-9) 是一种维生素 K2 类似物，已在包括大肠杆菌在内的各种细菌中发现。Menaquinone 9 对紫外线敏感，可与细菌电子传输链的一种成分可溶性硝酸还原酶结合。
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...

同位素标记化合物

Cat.No: T29867

Synonym: C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A

Cat.No: T34590

Synonym: Venlafaxine deuterium-substituted,D9-venlafaxine

L-Lactic acid-13C3

Cat.No: T41001

Synonym: L-Lactic acid-13C3,(S)-2-hydroxypropanoic-13-C3

Cat.No: TMIH-0555

Maxacalcitol-D6

Cat.No: T11952

Target: Others

Cat.No: T74145

Cat.No: TMID-0301

Cat.No: TMID-0300

ent-Thiamphenicol-d3

Cat.No: TMIJ-0034

Methotrexate-d3

Cat.No: TMIH-0335

Target: ADC Cytotoxin

Dronedarone-d6 HCl

Cat.No: TMIJ-0138

Cat.No: TMIJ-0029

Cat.No: TMIJ-0279

5-Fluorouracil-13C,15N2

Cat.No: T36895

Synonym: 5-Fluorouracil-13C,15N2

Cat.No: TMIJ-0217

Lamivudine-13C-d2

Cat.No: TMID-0285

Thiamphenicol-Methyl-d3

Cat.No: TMIJ-0022

Stavudine-α,α,α,6-d4

Cat.No: TMID-0266

Cat.No: TMIJ-0306

Molnupiravir-d7

Cat.No: TMIH-0354

Synonym: EIDD-2801-d7

Sofosbuvir-13C-d3

Cat.No: TMIH-0524

Hydrocortisone-d4

Cat.No: TMIJ-0193

Cat.No: TMIJ-0013

Cortisol-1,2-d2

Cat.No: TMID-0229

Cat.No: TMID-0061

Zanamivir-13C,15N2

Cat.No: T38118

Synonym: Zanamivir-13C,15N2

Menaquinone-9-d7

Cat.No: TMID-0041

Synonym: Vitamin K2-MK9-d7

Cat.No: T38297

Synonym: Ribavirin-13C5

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