首页工具

登录

搜索结果

Search Results for " snx "

Targets Recommended: HSP

13

抑制剂 & 化合物

3

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T28824	SNX0723 SNX 0723,SNX- 0723	HSP	Cytoskeletal Signaling; Metabolism
	SNX0723 是一种 Hsp90 抑制剂，具有抗疟原虫活性。SNX0723 对 HsHsp90 和 PfHsp90 具有高结合亲和力，Ki 分别为 4.4 和 47 nM。SNX0723 抑制肝期伯氏疟原虫 ANKA 寄生虫，EC50 为 3.3 μM。
T6305	SNX2112 SNX-2112,PF 04928473,SNX 2112	HSP	Cytoskeletal Signaling; Metabolism
	SNX2112 (PF 04928473) 是一种具有口服活性的 Hsp90 抑制剂，Kd 为 16 nM。
TP2118	SNX-482 SNX 482
	Potent and selective, voltage-dependent R-type CaV2.3 calcium channel blocker (IC50 = 30 nM). Antinociceptive; inhibits nociceptive C-fibre and Aδ-fibre-evoked neuronal responses.
T6341	PF04929113 PF-04929113,SNX-5422,PF 04929113	HSP; HER	Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
	PF04929113 (SNX-5422) 是一种合成的新型小分子 Hsp90 抑制剂。作为一种具有强大疗效和耐受性的口服制剂，它被定位为一种突破性疗法，在广泛的癌症中具有广泛的适用性。
T77613	SNX7 WAY-323879	CDK	Cell Cycle/Checkpoint
	SNX7 (WAY-323879) 是细胞周期蛋白依赖性激酶抑制剂 (CDKI) 途径的抑制剂。 SNX7 可用作研究衰老过程和与 CDKI 相关的其他疾病的工具。
T68393	SNX-7081	Others	Others
	NX-7081 is a novel small molecule inhibitor of Hsp90, which blocks components of inflammation, including cytokine production, protein kinase activity, and angiogenic signaling. SNX-7081 showed strong binding affinity to Hsp90 and expected induction of Hsp70. NF-kappaB nuclear translocation was blocked by SNX-7081 at nanomolar concentrations, and cytokine production was potently inhibited. Growth factor activation of ERK and JNK signaling was significantly reduced by SNX-7081. NO production was a...
T4342	PF-04929113 Mesylate PF-04929113 (Mesylate),SNX-5422 Mesylate	HSP; HER	Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
	PF-04929113 Mesylate (SNX-5422 Mesylate) 是 SNX-2112 的前药，是一种可口服的 Hsp90 抑制剂 (Kd: 41 nM)，还可诱导 Her-2 降解 (IC50: 37 nM)。
T24811	SNX2-1-108 SNX-21108,SNX21108,SNX 21108	Others	Others
	SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.
T80443	ω-Conotoxin MVIID SNX-238	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	ω-Conotoxin MVIID (SNX-238) 是芋螺肽，能抑制ω-Conotoxin-GVIA敏感的高阈值Ca2+电流于鱼类视网膜神经节细胞。
TP1559L	Ziconotide Acetate (107452-89-1 free base) 醋酸齐考诺肽,Prialt,Ziconotide Acetate	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Ziconotide Acetate (107452-89-1 free base) (Prialt) 是一种镇痛剂，已用于治疗神经性和非神经性疼痛。 Ziconotide 通过与位于伤害感受通路初级传入神经元末端部分的 N 型钙通道结合起作用，因此通过有效的镇痛作用减少突触传递。
T81137	SNX7886	PROTACs	PROTAC
	SNX7886为高效CDK8/19蛋白降解剂，在293细胞中可分别降解CDK8与CDK19至90%及80%。
T18018	HS-27	Others; HSP	Cytoskeletal Signaling; Metabolism; Others
	HS-27 是一种荧光束缚的 Hsp90 抑制剂，SNX-5422 通过 PEG 接头束缚在异硫氰酸荧光素或 FITC 上。 HS-27 可用于“即看即治”模式。
T75710	Ziconotide TFA
	Ziconotide TFA (SNX-111 TFA)，一种肽类化合物，作为高效且选择性的N型钙通道拮抗剂，能减少突触传递，适用于慢性疼痛的研究。

化合物

Cat.No: T28824

Synonym: SNX 0723,SNX- 0723

Target: HSP

Cat.No: T6305

Synonym: SNX-2112,PF 04928473,SNX 2112

Target: HSP

Cat.No: TP2118

Synonym: SNX 482

Cat.No: T6341

Synonym: PF-04929113,SNX-5422,PF 04929113

Target: HSP, HER

Cat.No: T77613

Synonym: WAY-323879

Target: CDK

Cat.No: T68393

Target: Others

PF-04929113 Mesylate

Cat.No: T4342

Synonym: PF-04929113 (Mesylate),SNX-5422 Mesylate

Target: HSP, HER

Cat.No: T24811

Synonym: SNX-21108,SNX21108,SNX 21108

Target: Others

ω-Conotoxin MVIID

Cat.No: T80443

Synonym: SNX-238

Target: Calcium Channel

Ziconotide Acetate (107452-89-1 free base)

Cat.No: TP1559L

Synonym: 醋酸齐考诺肽,Prialt,Ziconotide Acetate

Target: Calcium Channel

Cat.No: T81137

Target: PROTACs

Cat.No: T18018

Target: Others, HSP

Cat.No: T75710

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00888	ANXA7 Protein, Human, Recombinant Annexin A7,Annexin-7,Synexin,ANXA7,Annexin VII,SNX,...	Human	E. coli
	Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal region is composed of alternating hydrophobic and hydrophilic segments. Annexin A7 is a calcium/phospholipid-binding protein with diverse properties including voltage-sensitive calcium channel activity and promotes membrane fusion and is also involved in exocytosis.
TMPH-02127	SNX16 Protein, Human, Recombinant (His) Sorting nexin-16,SNX16	Human	E. coli
	May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
TMPH-02301	VPS35 Protein, Human, Recombinant (His & Myc) VPS35,Vacuolar protein sorting-associated protein 35,Vesicle...	Human	E. coli
	Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of...

重组蛋白

ANXA7 Protein, Human, Recombinant

Cat.No: TMPJ-00888

Species: Human

Expression System: E. coli

SNX16 Protein, Human, Recombinant (His)

Cat.No: TMPH-02127

Species: Human

Expression System: E. coli

VPS35 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02301

Species: Human

Expression System: E. coli

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼