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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16089 |
MK-0674
|
Cysteine Protease | Proteases/Proteasome |
MK-0674 是一种可口服且具有选择性和高效性的 cathepsin K 抑制剂(IC50:0.4 nM),抑制 Cat B、Cat F、Cat L 和 Cat S,可用于和代谢相关的疾病。 | |||
T18326 |
MC-Val-Cit-PAB-MMAF
|
Others; Drug-Linker Conjugates for ADC | Antibody-drug Conjugate/ADC Related; Others |
MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB. | |||
T27595 |
Imarikiren HCl
TAK-272 hydrochloride,TAK-272 HCl. Imarikiren HCl |,TAK272,TAK 272,TAK-272 |
Others | Others |
Imarikiren is a potent, selective and orally active direct renin inhibitor. TAK-272 shows potent inhibitory activity against human renin (IC50 = 2.1 nM) in hPRA assay and excellent selectivity against other aspartic proteases, such as cathepsin D (IC50 > |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01060 |
Cathepsin F Protein, Human, Recombinant (His)
Cathepsin F,CTSF,CATSF |
Human | E. coli |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Cathepsin F Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is Q9UBX1. | |||
TMPJ-00708 |
CST7 Protein, Mouse, Recombinant (His)
CMAP,Cystatin-7,Leukocystatin,Cystatin-like Metastasis-Assoc... |
Mouse | HEK293 Cells |
Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a biomarker for both liver metastasis and inflammatory lung disorders. Mouse Cystatin F inhibits papain and cathepsin L but with affinities lower than other cystatins. It may play a role in immune regulation through inhibition of a unique target in the hematopoietic system. |