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  • 抑制剂&激动剂
    39
    TargetMol | Inhibitors_Agonists
  • 化合物库
    1
    TargetMol | Compound_Libraries
  • 重组蛋白
    2
    TargetMol | Recombinant_Protein
  • 多肽产品
    1
    TargetMol | Peptide_Products
  • 染料试剂
    1
    TargetMol | Dye_Reagents
  • PROTAC
    1
    TargetMol | PROTAC
  • 天然产物
    5
    TargetMol | Natural_Products
  • 试剂盒
    2
    TargetMol | Reagent_Kits
  • 分子与细胞研究
    3
    TargetMol | Inhibitors_Agonists
  • Enflurane
    恩氟烷, NSC-115944, NSC115944, NSC 115944, Ethrane, Efrane
    T1965813838-16-9
    Enflurane (Efrane) 是一种挥发性麻醉剂,是 Chara australis 高电导 Ca2+ 激活的 K+ 通道的有效抑制剂。 安氟醚是通过顶空气相色谱-质谱法监测卤化挥发性麻醉剂的内标。 它可以快速调整麻醉深度,而脉搏或呼吸频率几乎没有变化。
    • ¥ 198
    In stock
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  • α-Cyano-4-hydroxycinnamic acid
    2-氰基-4-羟基, α-Cyano-4-hydroxycinnamic acid(α-CHCA)
    T746028166-41-8
    α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) 是非竞争性单羧酸盐转运蛋白 (MCTs) 抑制剂,可抑制线粒体丙酮酸转运蛋白,Ki 值为 6.3 μM。它可作为基质辅助激光解吸电离-飞行时间质谱 (MALDI-TOF) 分析的基质,可以促进肽离子化。
    • ¥ 313
    In stock
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  • Hydroxy Dimetridazole
    T37514936-05-0
    Hydroxy Dimetridazole 是Dimetridazol 的羟基化代谢产物。Dimetridazol 是一种硝基咪唑类药物,可用于对抗原生动物感染。
    • ¥ 123
    In stock
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  • 6-Hydroxynicotinic acid
    6-Hydroxypyridine-3-carboxylic acid, 6-羟基烟酸, 2-Hydroxy-5-pyridinecarboxylic acid
    T48165006-66-6
    6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) 用于核磁共振波谱或气相色谱-质谱法诊断尿路感染中的铜绿假单胞菌。在引起尿液感染的常见细菌中,只有铜绿假单胞菌从烟酸中产生6-羟基烟酸。
    • ¥ 99
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    TargetMol | Inhibitor Sale
  • 1-Thioglycerol
    alpha-Thioglycerol, 1-硫代甘油
    T8484696-27-5
    1-Thioglycerol(1-硫代甘油)是一种抗氧化的硫代甘油,作为培养基成分可以清除自由基和减少氧化应激,在快速原子轰击质谱法(FAB-MS)和液体二次离子质谱法(LSIMS)中用作基质。
    • ¥ 99
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  • Ammonium trifluoroacetate
    TSH-002353336-58-1
    Ammonium trifluoroacetate 是用于调节和校准新液相色谱 质谱系统的添加剂。
    • ¥ 99
    In stock
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  • Oleoyl proline
    N-Oleoyl-l-proline
    T33789107432-37-1
    Oleoyl proline is an N-acyl amine that can be detected in bovine brain extracts and D. melanogaster larvae using mass spectrometry. In a preclinical model of pain, mice lacking fatty acid amide hydrolase (FAAH KO) had decreased N-oleoyl proline levels in
    • 待估
    1-2周
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  • 18:0 LYSO-PE
    Stearoyl lysophosphatidylethanolamine
    T1390469747-55-3
    18:0 LYSO-PE是一种诱导[Ca2+]i增加的化合物,18:0 LYSO-PE可用作电喷雾质谱(ESI-MS) MS进行脂质分析的磷脂(PL)标准。
    • ¥ 916
    In stock
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  • Cholesteryl behenate
    胆固醇山萮酸酯, Cholesteryl docosanoate, Cholesterol behenate
    T1923661510-09-6
    Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesteryl esters and cholesterol.
    • 待估
    35日内发货
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  • Glutarylcarnitine
    戊二酰基肉碱, O-glutaroyl-L-carnitine
    T19340102636-82-8
    Glutarylcarnitine (O-glutaroyl-L-carnitine) 是大多数串联质谱新生儿筛查计划中监测的丙二酸尿症和谷草酸尿症 I 型的诊断代谢物。
    • ¥ 299
    In stock
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  • N,N'-Carbonyldiimidazole
    N,N'-羰基二咪唑(CDI), N,N'-Carbonyldiimidazole, CDI Crosslinker, 1,1'-Carbonyldiimidazole
    T19945530-62-1
    N,N'-Carbonyldiimidazole 是一种生物交联剂,在质谱检测化合物纯度上有很大的应用。
    • ¥ 108
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  • 1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE
    18:0p 22:6-PE
    T201867206059-98-5
    1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p 22:6-PE) 为一种通过质谱成像技术在大鼠脑组织中确认的独特结构脂质,此方法可准确识别其不同脂肪酸链的异构体及其分布。
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  • Cardiolipin (16:0/18:1/16:0/18:1) sodium
    棕榈酰-油酰心磷脂, 16:0-18:1 Cardiolipin sodium
    T2032642260669-35-8
    Cardiolipin (16:0 18:1 16:0 18:1) (16:0-18:1 Cardiolipin) sodium 是一种含有饱和棕榈酸和单不饱和油酸的阴离子磷脂。Cardiolipin (16:0 18:1 16:0 18:1) sodium 适用于纳米磷脂盘的合成,并用于原位质谱分析。
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  • Lasiocarpine N-oxide
    4-21-00-02054 (Beilstein Handbook Reference)
    T25634127-30-0
    Lasiocarpine N-oxide is a natural compound found to be higher in many tea bags, herbal drugs and honey by mass spectrometry.
    • 待询
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  • Robinin
    刺槐素, NSC 9222
    T2S0265301-19-9
    Robinin是一种来源于Robinia的黄酮苷类化合物,具有抗菌和利尿的特性,其衍生自kaempferol。通过监测Colo 320细胞系(表达MDR1 LRP)对Rhodamine 123的吸收情况,探讨了robinin逆转人类结肠癌细胞多药耐药性的能力,但结果显示其效果有限。在使用液相色谱-串联质谱法检测人类乳腺癌细胞系MCF-7的细胞裂解物时,发现了Robinin (NSC-9222)的存在。
    • ¥ 690
    In stock
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  • (±)10-HDHA
    T3550490780-50-0
    (±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.[1][2] It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.[3][4][5] (±)10-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid. Reference:[1]. VanRollins, M., and Murphy, R.C. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate. J. Lipid Res. 25(5), 507-517 (1984).[2]. Reynaud, D., Thickitt, C.P., and Pace-Asciak, C.R. Facile preparation and structural determination of monohydroxy derivatives of docosahexaenoic acid (HDoHE) by α-tocopherol-directed autoxidation. Anal. Biochem. 214(1), 165-170 (1993).[3]. VanRollins, M., Baker, R.C., Sprecher, H., et al. Oxidation of docosahexaenoic acid by rat liver microsomes. J. Biol. Chem. 259(9), 5776-5783 (1984).[4]. Yamane, M., Abe, A., and Yamane, S. High-performance liquid chromatography-thermospray mass spectrometry of epoxy polyunsaturated fatty acids and epoxyhydroxy polyunsaturated fatty acids from an incubation mixture of rat tissue homogenate. J. Chromatogr. 652(2), 123-136 (1994).[5]. Kim, H.Y., Karanian, J.W., Shingu, T., et al. Sterochemical analysis of hydroxylated docosahexaenoates produced by human platelets and rat brain homogenate. Prostaglandins 40(5), 473-490 (1990).
    • 待估
    35日内发货
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  • Pregnanetriol
    T356651098-45-9
    Pregnanetriol is a metabolite of 17α-hydroxyprogesterone .1,2It is formed from 17α-hydroxyprogesterone by reduction of the C-20 ketone.2Urinary levels of pregnanetriol are elevated in patients with 21-hydroxylase deficiency and congenital adrenal hyperplasia.3,4 1.Kamrath, C., Hartmann, M.F., Boettcher, C., et al.Diagnosis of 21-hydroxylase deficiency by urinary metabolite ratios using gas chromatography-mass spectrometry analysis: Reference values for neonates and infantsJ. Steroid Biochem. Mol. Biol.15610-16(2016) 2.Schiffer, L., Barnard, L., Baranowski, E.S., et al.Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive reviewJ. Steroid Biochem. Mol. Biol.194105439(2019) 3.Disorders of steroidogenesis guide to steroid profiling and biochemical diagnosis1(2019) 4.Shackleton, C.H.L.Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesisLipids47(1)1-12(2012)
    • 待估
    35日内发货
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  • N-desmethyl Rosuvastatin (sodium salt hydrate)
    T35718
    N-desmethyl Rosuvastatin is an active metabolite of the HMG-CoA reductase inhibitor rosuvastatin .1,2N-desmethyl Rosuvastatin is formed when rosuvastatin undergoes demethylation, primarily by the cytochrome P450 (CYP) isoform CYP2C9 and to a lesser extent by CYP2C19 and CYP3A4.1 1.Macwan, J.S., Ionita, I.A., and Akhlaghi, F.A simple assay for the simultaneous determination of rosuvastatin acid, rosuvastatin-5S-lactone, and N-desmethyl rosuvastatin in human plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS)Anal. Bioanal. Chem.402(3)1217-1227(2012) 2.Bai, X., Wang, X.P., He, G.D., et al.Simultaneous determination of rosuvastatin, rosuvastatin-5 S-lactone, and N-desmethyl rosuvastatin in human plasma by UPLC-MS/MS and its application to clinical studyDrug Res. (Stuttg.)68(6)328-334(2018)
    • ¥ 4970
    35日内发货
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  • Tolmetin β-D-Glucuronide
    T3612871595-19-2
    Tolmetin β-D-Glucuronide 与人血清白蛋白具有反应特性,可通过串联质谱法鉴定结合位点和反应机制。
    • ¥ 4230
    35日内发货
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  • MitoA
    T36223
    MitoA is a ratiometric mass spectrometry probe that can be used for assessing changes in H2S within mitochondria in vivo. MitoA contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its aryl azide moiety selectively reacts with H2S to produce an amine product, MitoN. Quantifying the MitoN MitoA ratio by LC-MS MS reflects the mitochondrial matrix H2S concentration. In a mouse model of acute myocardial infarction with MitoA administered prior to ischemia, the MitoN MitoA ratio is increased only in the region of ischemia.
    • 待估
    35日内发货
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  • Cholesteryl Heptadecanoate
    T3673124365-37-5
    Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques. CEs of various fatty acids are major constituents of murine and human adrenal glands.
    • 待估
    35日内发货
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  • N-3-hydroxydecanoyl-DL-Homoserine lactone
    T36989929222-14-0
    N-3-hydroxydecanoyl-DL-Homoserine lactone is a bacterial quorum-sensing molecule.1It activates SdiA (EC50= 0.6 μM), a transcription factor that detects N-acyl homoserine lactones (AHLs), in the 14028 pJNS25 strain ofS. enterica.2 1.Fekete, A., Frommberger, M., Rothballer, M., et al.Identification of bacterial N-acylhomoserine lactones (AHLs) with a combination of ultra-performance liquid chromatography (UPLC), ultra-high-resolution mass spectrometry, and in-situ biosensorsAnal. Bioanal. Chem.387455-467(2007) 2.Janssens, J.C.A., Metzger, K., Daniels, R., et al.Synthesis of N-acyl homoserine lactone analogues reveals strong activators of SdiA, the Salmonella enterica serovar Typhimurium LuxR homologueAppl. Environ. Microb.73(2)535-544(2007)
    • ¥ 1410
    35日内发货
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  • Dichloroiodomethane
    T37311594-04-7
    Dichloroiodomethane is a natural compound in human beings[1]. [1]. Lalith K. Silva, et al. Quantification of Dichloroiodomethane and Bromochloroiodomethane in Human Blood by Solid-Phase Microextraction Coupled with Gas Chromatography-High-Resolution Mass Spectrometry. Journal of Analytical Toxicology, Volume 30, Issue 9, November-December 2006, Pages 670-678.
    • ¥ 642
    5日内发货
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  • (±)11(12)-DiHET
    T37333
    (±)-11(12)-DiHET is an oxylipin. 11(S),12(S)-DiHET and 11(R),12(R)-DiHET are vicinal diols formedviaenzymatic hydration of 11(12)-EET by cytosolic or soluble epoxide hydrolases in a non-stereoselective manner.1,2,3(±)11(12)-DiHET MaxSpec standard is a quantitative grade standard of (±)11(12)-DiHET that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)11(12)-DiHET MaxSpec standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product.Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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