首页工具

登录

搜索结果

Search Results for " peroxidase "

Targets Recommended: Glutathione Peroxidase Others

53

抑制剂 & 化合物

7

天然产物

1

化合物库

25

重组蛋白

2

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L2900	氧化还原化合物库		1264 compounds
	1264 个活性化合物，已经验证具有一定的抗氧化活性，包括 ROS 清除剂、iNOS、eNOS、及抗氧化的天然产物，是研究疾病机理以及药物研究的优良载体

化合物库

氧化还原化合物库

Cat.No: L2900

Compounds: 1264

Cat. No.	Product Name	Target	Signaling Pathways
T19508	Peroxidase	Others	Others
	Peroxidase 来自辣根，在先天免疫、氧化活性氧、激素生物合成和多种疾病的发病机制等方面具有重要作用。
T80056	Glutathione Peroxidase GSH-Px,EC 1.11.1.9	Glutathione Peroxidase	Metabolism
	Glutathione Peroxidase (GSH-Px; EC 1.11.1.9)，是一种关键的抗氧化酶，能催化GSH与过氧化氢或脂质过氧化物反应，生成GSSG和H2O，从而减缓氧化应激。此酶在生化研究中具有重要应用。
T83780	GPX4 24 Phospholipid Hydroperoxide Glutathione Peroxidase 24,PHGPx 24,Glutathione Peroxidase 4 24	Others	Others
	GPX4 24是(1S,3R)-RSL3的衍生物，具有抑制谷胱甘肽过氧化物酶4（GPX4）的作用。它能够在浓度依赖的方式中与4T1小鼠乳腺癌细胞中的GPX4形成共价结合。在GPX4依赖的HT-1080成纤维细胞中，GPX4 24诱导铁死亡（EC50 = 0.16 µM）。当以200 mg/kg剂量给予小鼠时，它能够增加小鼠肾脏和血浆中丙二醛（MDA）的水平。
T37314	JKE-1674	GPX	oxidation-reduction
	JKE-1674 是口服有效的谷胱甘肽过氧化物酶 4 (GPX4)抑制剂，是ML-210的活性代谢物，ML-210也是GPX4抑制剂。它可转换成丁腈氧化物 JKE-1777。它用与 ML-210 相同的方式杀死 LOX-IMVI 细胞，并被ferroptosis 抑制剂完全挽救。
T5340	MPO-IN-28	Glutathione Peroxidase	Metabolism
	MPO-IN-28 是髓过氧化物酶 (MPO) 抑制剂，IC50=44 nM。
T8375	ML-210 CID 49766530	Ferroptosis; GPX; Glutathione Peroxidase; Ras	Apoptosis; GPCR/G Protein; MAPK; Metabolism; oxidation-reduction
	ML-210 (CID 49766530) 是一种共价的选择性谷胱甘肽过氧化物酶 4 (GPX4) 抑制剂，EC50为 30 nM。它与 GPX4 硒代半胱氨酸残基结合，具有抗癌活性。
T14379	AZD5904	Glutathione Peroxidase	Metabolism
	AZD5904 是一种不可逆的人髓过氧化物酶选择性抑制剂，其IC50=140 nM，在小鼠和大鼠中也具有相似的效力。
T4090	PF-06282999	Glutathione Peroxidase	Metabolism
	PF06282999 是选择性的髓过氧物酶 (myeloperoxidase) 抑制剂，用于研究心血管疾病。
T12189	NBDHEX	Apoptosis; Glutathione Peroxidase; Autophagy	Apoptosis; Autophagy; Metabolism
	NBDHEX 是一种谷胱甘肽 S-转移酶 P1-1 抑制剂，也是晚期自噬抑制剂。它诱导肿瘤细胞凋亡，通过抑制 GST 的催化活性，避免抑制剂被特异性泵从细胞中排出，以及破坏 GSTP1-1和关键信号传导因子之间的相互作用，从而起到抗癌的作用。
T5463	Verdiperstat AZD3241,AZD 3241	Glutathione Peroxidase	Metabolism
	Verdiperstat (AZD 3241) 是一种不可逆的、选择性的、口服具有活力的髓过氧化物酶 (myeloperoxidase) 抑制剂，IC50=630 nM，可用于研究大脑神经退行性疾病。
T8970	ML162	Ferroptosis; GPX; Glutathione Peroxidase	Apoptosis; Metabolism; oxidation-reduction
	ML162 是一种共价谷胱甘肽过氧化物酶 4 抑制剂。它选择性抑制表达突变 RAS 癌基因的细胞系。
T4313	Tinoridine hydrochloride 盐酸替诺立定,Nonflamin,Y-3642 hydrochloride	COX; Glutathione Peroxidase	Immunology/Inflammation; Metabolism; Neuroscience
	Tinoridine hydrochloride (Y-3642 hydrochloride) 是非甾体抗炎药，具有显著的自由基清除和抗过氧化物特性。
T3646	RSL3 RSL3 1S,1S,3R-RSL3	Ferroptosis; GPX; Glutathione Peroxidase	Apoptosis; Metabolism; oxidation-reduction
	RSL3 (RSL3 1S) 是一种 GPX4 的抑制剂，抑制阻断 GSH 合成的 system xc- (IC50=100 nM)。RSL3 是一种不依赖 VDAC 的铁死亡激活剂，对携带致癌 RAS 的肿瘤细胞具有选择性。
T26389	4-POBN NSC-640,NSC640,4-Aminobenzohydrazide,4-氨基苯甲酰肼,NSC 640,Myeloperoxidase Inhibitor 1,4-ABAH	Glutathione Peroxidase	Metabolism
	4-POBN (Myeloperoxidase Inhibitor 1) 是一种有效且不可逆的髓过氧化物酶抑制剂 (IC50 = 0.3 µM)。 4-POBN 可用于亚急性中风的研究。
T0825	Ebselen SPI-1005,PZ-51,依布硒,CCG-39161	Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Ebselen (CCG-39161) 是一种谷胱甘肽过氧化物酶模拟物，是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒，是HIV-1衣壳 CTD 二聚化的抑制剂，具有抗炎、抗癌和抗氧化活性。
T1374	2-Pyridinecarbohydrazide 2-吡啶甲酰肼,2-Picolinyl hydrazide	Dehydrogenase; CAT	Metabolism; oxidation-reduction
	2-Pyridinecarbohydrazide (2-Picolinyl hydrazide) 是 Catalase-peroxidase-NAPDH 的有效抑制剂。它普遍用于各种合成领域的砌块。
T18908	ABTS diammonium salt 2,2'-联氮双(3-乙基苯并噻唑啉-6-磺酸)二铵盐,AzBTS-(NH4)2	Others	Others
	ABTS diammonium salt (AzBTS-(NH4)2) 是辣根过氧化物酶的底物。
T0050	Ampyrone Minoazophene,Aminoantipyrin,NSC 60242,4-Aminoantipyrine,4-氨基安替比林,Solnapyrin-A	COX; Drug Metabolite	Immunology/Inflammation; Metabolism; Neuroscience
	Ampyrone (4-Aminoantipyrine) 是一种检测试剂，在过氧化物酶与苯酚存在时，用于葡萄糖测定。
T18912	ADHP 10-乙酰基-3,7-二羟基吩嗪,10-Acetyl-3,7-dihydroxyphenoxazine	Others	Others
	ADHP (10-Acetyl-3,7-dihydroxyphenoxazine) 是荧光过氧化物酶底物，其λex=530 nm，λem=590 nm。
T1309	Propylthiouracil 丙硫氧嘧啶,Pseudocapsaicin,NSC 6498,丙基硫氧嘧啶,NSC 70461,6-n-Propylthiouracil,6-Propyl-2-thiouracil	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Propylthiouracil (6-n-Propylthiouracil) 是一种甲状腺过氧化物酶抑制剂，也是一种5'-脱碘酶抑制剂。
T9734	InhA-IN-2	CDK	Cell Cycle/Checkpoint
	InhA-IN-2直接抑制 InhA，不需要过氧化氢酶过氧化物酶 KatG 的激活。
T9416	Dansylglycine	Others	Others
	Dansylglycine 是一种荧光探针，用于特异性测定髓过氧化物酶和嗜酸性粒细胞过氧化物酶的卤化活性。
Fr16629	4-(Imidazol-1-yl)phenol	Others	Others
	4-(Imidazol-1-yl)phenol 是一种高效信号增强剂，用于辣根过氧化物酶（HRP）-鲁米诺化学发光（CL）免疫测定。
T19069	TMB dihydrochloride 3,3',5,5'-四甲基联苯胺盐酸盐,BM blue dihydrochloride,Sure Blue TMB dihydrochloride,3,3',5,5'-Tetramethylbenzidine dihydrochloride	Others	Others
	TMB dihydrochloride (Sure Blue TMB dihydrochloride) 是一种免疫组化和 ELISA 的显色底物。
T18972	DHBS DCHBS	Others	Others
	DHBS (DCHBS) 与 4-氨基安替比林和过氧化氢联合使用，能够用于偶联酶促反应中过氧化物酶的显色定量。它是 Trinder 试剂的组分，能够与过氧化物酶一起测量过氧化氢的产生。
T67498	3-Amino-1,2,4-triazole Amitrole,3-AT,1H-1,2,4-Triazol-5-amine,Trapidil impurity B	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	3-Amino-1,2,4-triazole (Trapidil impurity B) 是一种过氧化氢酶抑制剂，能够诱导过氧化氢解毒的补偿机制。该机制涉及增加谷胱甘肽过氧化物酶和谷胱甘肽还原酶的活性。
T9423	Alkyne tyramide	Others	Others
	Alkyne tyramide 是抗坏血酸过氧化物酶 2 探针。它有助于鉴定 APEX 标记位点，明确线粒体蛋白的膜拓扑的分配。它显著提高了完整酵母细胞的 APEX 标记效率，比 APEX2 底物生物素苯酚具有更大的细胞壁渗透性。
T0664	Nicotinic acid hydrazide	Others	Others
	Nicotinic acid hydrazide（NAH）是烟酸的酰肼衍生物，一种杂环有机物，是过氧化物酶抑制剂，可以形成具有较强生物活性的固态金属配合物。
T36935	PKUMDL-LC-101-D04 GPX4-Activator-1d4,PKUMDL-LC-101-D04	GPX	oxidation-reduction
	PKUMDL-LC-101-D04是一种高效的谷胱甘肽过氧化物酶4（GPX4）的异位激活剂，是一种铁死亡的调节剂。当在无细胞试验中使用浓度为20 μM 时，GPX4活性增加到对照水平的150%；在野生型而非Gpx4-/-小鼠胚胎成纤维细胞(MEF)提取物中使用浓度为61 μM 时，GPX4活性增加到对照水平的150%。PKUMDL-LC-101-D04（200 μM）能减少胆固醇过氧化氢诱导的MEF 死亡。
T38010	PPHP	Others	Others
	PPHP is a substrate for the measurement of peroxidase enzymes. PPHP has been used to quantitate the peroxidase activity of COX-1 and COX-2.
T39152	4-Hydroxyphenylbutazone	Others	Others
	4-Hydroxyphenylbutazone, a metabolite of Phenylbutazone, functions as an effective reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its efficiency in this role.
T38914	MPO-IN-3	Others	Others
	MPO-IN-3, a powerful inhibitor of myeloperoxidase (MPO), is described as such in example 191 of WO2013068875A1. MPO, a heme-containing enzyme, is classified under the peroxidase superfamily.
T39181	Cyanine 3 Tyramide Cyanine 3 Tyramide,Tyramide-Cy3
	Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, serves as a reporter fluorescent substrate in horseradish peroxidase (HRP)-catalyzed deposition for signal amplification in immunoassays and in situ nucleic acid hybridization.
T39686	1-Methoxynaphthalene	Others	Others
	1-Methoxynaphthalene is employed as a substrate for scrutinizing the enzymatic activity of cytochrome c peroxidase (CcP). Additionally, 1-Methoxynaphthalene can serve as a precursor for the synthesis of prenyl naphthalen-ols.
T38902	Cyanine 5 Tyramide Tyramide-Cy5
	Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, serves as a reporter fluorescent substrate in horseradish peroxidase (HRP)-catalyzed deposition, a signal amplification method employed in immunoassays and in situ hybridization of nucleic acids.
TP1096	Elamipretide TFA SS-31 (TFA),MTP-131 (TFA),RX-31 (TFA)	Others	Others
	Elamipretide TFA (RX-31 TFA) 是一种心磷脂过氧化物酶抑制剂和线粒体靶向肽[。
T40137	MPO-IN-1	Others	Others
	MPO-IN-1 is a powerful and orally bioavailable indole-containing inhibitor that acts irrevocably on myeloperoxidase (MPO). With IC50 values of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively, MPO-IN-1 effectively inhibits both enzymes. Furthermore, it exhibits remarkable MPO inhibitory activity in an acute inflammation mouse model.
T37805	JKE-1716	Others	Others
	JKE-1716 is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of the GPX4 inhibitor ML-210 .1JKE-1716 reduces viability of LOX-IMVI cancer cells in a concentration-dependent manner and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 . 1.Eaton, J.K., Furst, L., Ruberto, R.A., et al.Selective covalent targeting of GPX4 using masked nitrile-oxide electrophilesNat. Chem. Biol.16(5)497-506(2020)
T81340	Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone PCNPH
	Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone (PCNPH) 作为一种过氧化物酶显色底物，能与过氧化物酶及过氧化物反应生成紫色吲哚染料。
T38099	APF
	APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxim...
T36516	RC574 RC574	Others	Others
	RC574 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol .1It inhibits glutamate-induced cell death in HT22 cells (IC50= 276.2 nM) and mouse primary cortical neurons when used at a concentration of 3 μM. RC574 (3 μM) increases glutathione peroxidase 1 (GPX1) levels and GPX activity, as well as inhibits glutamate-induced mitochondrial superoxide anion production, in HT22 cells. It completely inhibits ferroptosis induced by the GPX4 inhibitor ...
T36515	RC363	Others	Others
	RC363 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol .1It reduces 2,2-diphenyl-1-picrylhydrazyl radicals by approximately 40% in a cell-free assay when used at a concentration of 25 μM. RC363 prevents glutamate-induced toxicity in HT22 cultured hippocampal cells (IC50= 234.5 nM) but does not reduce oxidant levels in these cells. It increases the levels of glutathione peroxidase 1 (GPX1) and the activity of GPX in glutamate-challenged HT2...
T11357	Gamma-glutamylcysteine TFA γ-glutamylcysteine (TFA),Gamma-glutamylcysteine (TFA)	IL Receptor	Immunology/Inflammation
	Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes. Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx).
T63729	GPX4-IN-3	Others	Others
	GPX4-IN-3 (26a) 作为一种有效的谷胱甘肽过氧化物酶4 (GPX4) 抑制剂，其能选择性诱导铁死亡（ferroptosis）。在1 μM浓度下，该化合物能抑制GPX4活性达71.7%。
T60281	MPO-IN-4	Others	Others
	MPO-IN-4 (compound 12) 是一种有效的选择性髓过氧化物酶 (MPO) 抑制剂，IC50为 25 nM。MPO-IN-4对甲状腺过氧化物酶(TPO)也显示抑制作用，IC50为2.2 μM。MPO-IN-4 对甲基鸟嘌呤甲基转移酶 (MGMT) 没有影响。
T74073	Cyanine 5 Tyramide methyl indole	Others	Others
	Cyanine 5 Tyramide (Tyramide-Cy5) methyl indole 为红色荧光染料，用于HRP催化沉积报告中作为荧光底物，应用于免疫测定及核酸原位杂交信号放大。储存须避光。
T84581	Prostaglandin G2 PGG2	Others	Others
	Prostaglandin G2 (PGG2) serves as the initial stable intermediate in the COX pathway, identifiable and characterizable due to its stability. This compound is identified as the C-15 hydroperoxide derivative of PGH2. Typically, PGG2 undergoes rapid metabolism via the inherent peroxidase activity of both COX-1 and COX-2 enzymes, resulting in the production of PGH2. PGH2 is crucial as it is the primary precursor for the generation of 2-series prostaglandins and thromboxanes.
T78406	Cyanine 3 Tyramide methyl indole
	Cyanine 3 Tyramidemethyl indole为Cyanine 3 Tyramide（Tyramide-Cy3）的衍生物，后者作为一种橙色荧光染料，在免疫测定和核酸原位杂交技术中，用作辣根过氧化物酶（HRP）催化沉积的报告荧光底物，用于信号放大。
T75028	TMV-IN-4	Others	Others
	TMV-IN-4（compound 3）是一种针对烟草花叶病毒（TMV）的抑制剂。该化合物通过与TMV解旋酶交互作用，能够诱导植物产生抗性并提高对TMV感染的耐受性。TMV-IN-4还可增强过氧化物酶和超氧化物歧化酶活性，从而提升烟草的TMV抗性。
T85266	3-Bromotyrosine TFA 3-bromo-Tyr	Others	Others
	3-Bromotyrosine, a product of protein oxidation, is generated after eosinophil activation during allergic responses. It serves as a biomarker for eosinophil peroxidase-induced protein oxidation both in vitro and in vivo. Beyond its association with eosinophils, 3-bromotyrosine levels are significantly elevated in peritoneal exudate from K. pneumoniae-infected mice, indicating a fivefold increase compared to uninfected controls, which implies that neutrophils may release increased levels of oxidi...

化合物

Cat.No: T19508

Target: Others

Glutathione Peroxidase

Cat.No: T80056

Synonym: GSH-Px,EC 1.11.1.9

Target: Glutathione Peroxidase

Cat.No: T83780

Synonym: Phospholipid Hydroperoxide Glutathione Peroxidase 24,PHGPx 24,Glutathione Peroxidase 4 24

Target: Others

Cat.No: T37314

Target: GPX

Cat.No: T5340

Target: Glutathione Peroxidase

Cat.No: T8375

Synonym: CID 49766530

Target: Ferroptosis, GPX, Glutathione Peroxidase, Ras

Cat.No: T14379

Target: Glutathione Peroxidase

Cat.No: T4090

Target: Glutathione Peroxidase

Cat.No: T12189

Target: Apoptosis, Glutathione Peroxidase, Autophagy

Cat.No: T5463

Synonym: AZD3241,AZD 3241

Target: Glutathione Peroxidase

Cat.No: T8970

Target: Ferroptosis, GPX, Glutathione Peroxidase

Tinoridine hydrochloride

Cat.No: T4313

Synonym: 盐酸替诺立定,Nonflamin,Y-3642 hydrochloride

Target: COX, Glutathione Peroxidase

Cat.No: T3646

Synonym: RSL3 1S,1S,3R-RSL3

Target: Ferroptosis, GPX, Glutathione Peroxidase

Cat.No: T26389

Synonym: NSC-640,NSC640,4-Aminobenzohydrazide,4-氨基苯甲酰肼,NSC 640,Myeloperoxidase Inhibitor 1,4-ABAH

Target: Glutathione Peroxidase

Cat.No: T0825

Synonym: SPI-1005,PZ-51,依布硒,CCG-39161

Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease

2-Pyridinecarbohydrazide

Cat.No: T1374

Synonym: 2-吡啶甲酰肼,2-Picolinyl hydrazide

Target: Dehydrogenase, CAT

ABTS diammonium salt

Cat.No: T18908

Synonym: 2,2'-联氮双(3-乙基苯并噻唑啉-6-磺酸)二铵盐,AzBTS-(NH4)2

Target: Others

Cat.No: T0050

Synonym: Minoazophene,Aminoantipyrin,NSC 60242,4-Aminoantipyrine,4-氨基安替比林,Solnapyrin-A

Target: COX, Drug Metabolite

Cat.No: T18912

Synonym: 10-乙酰基-3,7-二羟基吩嗪,10-Acetyl-3,7-dihydroxyphenoxazine

Target: Others

Propylthiouracil

Cat.No: T1309

Synonym: 丙硫氧嘧啶,Pseudocapsaicin,NSC 6498,丙基硫氧嘧啶,NSC 70461,6-n-Propylthiouracil,6-Propyl-2-thiouracil

Target: Thyroid hormone receptor(THR)

Cat.No: T9734

Target: CDK

Cat.No: T9416

Target: Others

4-(Imidazol-1-yl)phenol

Cat.No: Fr16629

Target: Others

TMB dihydrochloride

Cat.No: T19069

Synonym: 3,3',5,5'-四甲基联苯胺盐酸盐,BM blue dihydrochloride,Sure Blue TMB dihydrochloride,3,3',5,5'-Tetramethylbenzidine dihydrochloride

Target: Others

Cat.No: T18972

Synonym: DCHBS

Target: Others

3-Amino-1,2,4-triazole

Cat.No: T67498

Synonym: Amitrole,3-AT,1H-1,2,4-Triazol-5-amine,Trapidil impurity B

Target: Reactive Oxygen Species

Alkyne tyramide

Cat.No: T9423

Target: Others

Nicotinic acid hydrazide

Cat.No: T0664

Target: Others

PKUMDL-LC-101-D04

Cat.No: T36935

Synonym: GPX4-Activator-1d4,PKUMDL-LC-101-D04

Target: GPX

Cat.No: T38010

Target: Others

4-Hydroxyphenylbutazone

Cat.No: T39152

Target: Others

Cat.No: T38914

Target: Others

Cyanine 3 Tyramide

Cat.No: T39181

Synonym: Cyanine 3 Tyramide,Tyramide-Cy3

1-Methoxynaphthalene

Cat.No: T39686

Target: Others

Cyanine 5 Tyramide

Cat.No: T38902

Synonym: Tyramide-Cy5

Elamipretide TFA

Cat.No: TP1096

Synonym: SS-31 (TFA),MTP-131 (TFA),RX-31 (TFA)

Target: Others

Cat.No: T40137

Target: Others

Cat.No: T37805

Target: Others

Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone

Cat.No: T81340

Synonym: PCNPH

Cat.No: T38099

Cat.No: T36516

Synonym: RC574

Target: Others

Cat.No: T36515

Target: Others

Gamma-glutamylcysteine TFA

Cat.No: T11357

Synonym: γ-glutamylcysteine (TFA),Gamma-glutamylcysteine (TFA)

Target: IL Receptor

Cat.No: T63729

Target: Others

Cat.No: T60281

Target: Others

Cyanine 5 Tyramide methyl indole

Cat.No: T74073

Target: Others

Prostaglandin G2

Cat.No: T84581

Synonym: PGG2

Target: Others

Cyanine 3 Tyramide methyl indole

Cat.No: T78406

Cat.No: T75028

Target: Others

3-Bromotyrosine TFA

Cat.No: T85266

Synonym: 3-bromo-Tyr

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5372	L-SelenoMethionine L-(+)-Selenomethionine,L-硒代蛋氨酸	Apoptosis; Amino Acids and Derivatives; Endogenous Metabolite	Apoptosis; Metabolism
	L-SelenoMethionine (L-(+)-Selenomethionine) 是 Selenomethionine 的 L-异构体，是硒的主要天然食物形式。它是一种癌症化学预防剂，可以增加谷胱甘肽过氧化物酶的表达，还可以通过饮食补充降低癌症的发生率并诱导癌细胞凋亡。
TJS0338	4-Methylesculetin 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭	Antioxidant; Glutathione Peroxidase	Metabolism; oxidation-reduction
	4-Methylesculetin (Methylesculetin) 是口服具有活力的天然香豆素衍生物，有抗氧化、抗炎特性。它可抑制myeloperoxidase 的特性，抑制 IL-6 的水平
T0657	Veratryl alcohol 3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇	Others	Others
	3,4-Dimethoxybenzyl alcohol 是木质素降解真菌的次级代谢产物，通常作为非酚性底物测定木质素分解活性。Veratryl alcohol 保护木质素过氧化物酶 (LiP) 避免因为 H2O2 而失活并且防止 LiP III 化合物的累积[3]
TL0009	coniferin Coniferoside,松柏苷,Abietin	Others; Antifungal	Microbiology/Virology; Others
	Coniferin (Abietin) 是一种松柏醇中的葡萄糖苷。它抑制真菌生长和黑化反应，具有 ATP 依赖性转运活性并具有抗氧化作用。
T19117	3-Deoxyglucosone 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose	GPX; Glucagon Receptor	GPCR/G Protein; oxidation-reduction
	3-Deoxyglucosone(3-Deoxy-D-glucosone) 是美拉德反应和多元醇反应的中间体途径合成。3-Deoxyglucosone 与蛋白质氨基快速反应形成晚期糖基化末端蛋白 (AGEs)。3-Deoxyglucosone 可使谷胱甘肽过氧化物酶失活，可与低葡萄糖协同作用以增强 GLP-1 分泌，可以作为糖尿病生物学检测的标志物。
T13753	(±)-Licarin A (±)-trans-Dehydrodiisoeugenol	Others	Others
	(±)-Licarin A ((±)-trans-Dehydrodiisoeugenol) is a dihydrobenzofuran neolignan, the resultant of an oxidative coupling reaction of isoeugenol and horseradish peroxidase (HRP) enzyme. (±)-Licarin A shows 100% parasites mortality at 200 μM.
T73465	Goitrin L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone	Others	Others
	Goitrin ((S)-Goitrin) 为芥子油苷-黑芥子酶反应产物，有效抑制甲状腺过氧化物酶并阻碍碘在甲状腺的利用。此外，该化合物亦展现出对抗流感病毒(H1N1)的活性。

天然产物

L-SelenoMethionine

Cat.No: T5372

Synonym: L-(+)-Selenomethionine,L-硒代蛋氨酸

Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite

4-Methylesculetin

Cat.No: TJS0338

Synonym: 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭

Target: Antioxidant, Glutathione Peroxidase

Veratryl alcohol

Cat.No: T0657

Synonym: 3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇

Target: Others

Cat.No: TL0009

Synonym: Coniferoside,松柏苷,Abietin

Target: Others, Antifungal

3-Deoxyglucosone

Cat.No: T19117

Synonym: 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose

Target: GPX, Glucagon Receptor

Cat.No: T13753

Synonym: (±)-trans-Dehydrodiisoeugenol

Target: Others

Cat.No: T73465

Synonym: L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) thyroid peroxidase,MSA,TPX,TDH2A	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPH-02407	Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc) mnp2c,Peroxidase	Lentinula edodes	E. coli
	Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03108	GPX5 Protein, Pig, Recombinant (E. coli, His & Myc) GPX5,Glutathione peroxidase 5,Epididymis-specific g...	Sus scrofa (Pig)	E. coli
	May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX...
TMPH-03443	GPX2 Protein, S. cerevisiae, Recombinant (His & Myc) Glutathione peroxidase homolog 2,Glutathione pe...	Saccharomyces cerevisiae	E. coli
	Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the presence of Ca(2+). Has peroxidase activity using preferentially thioredoxin as a reducing power. The redox state of the mitochondrial GPX2 is regulated by TRX1 and TRX2 (cytoplasmic thioredoxin), and by TRX3 (mitochondrial matrix thioredoxin). Involved in sporulation. GPX2 Protein, ...
TMPH-01296	GPX5 Protein, Human, Recombinant (GST & His) GPX5,Glutathione peroxidase 5,Epididymal secretory ...	Human	E. coli
	Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
TMPH-03109	GPX5 Protein, Pig, Recombinant (His & Myc) GPX5,Epididymis-specific glutathione peroxidase-lik...	Sus scrofa (Pig)	P. pastoris (Yeast)
	May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX...
TMPH-02681	GPX7 Protein, Mouse, Recombinant (His & Myc) Glutathione peroxidase 7,Gpx7	Mouse	E. coli
	It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. GPX7 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is Q99LJ6.
TMPH-01600	Lactoperoxidase/LPO Protein, Human, Recombinant (His & Myc) LPO,Salivary peroxidase,Lactoperoxidase	Human	HEK293 Cells
	Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May contribute to airway host defense against infection.
TMPH-00096	APX2, cytosolic Protein, Arabidopsis thaliana, Recombinant (His) APX1b,APX2,L-ascorbate peroxidase 2, cytosolic,L-as...	Arabidopsis thaliana	E. coli
	APX2, cytosolic Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.5 kDa and the accession number is Q1PER6.
TMPK-00874	Thyroid Peroxidase Protein, Mouse, Recombinant (His) MK-CSF,MGDF,ML,MPLLG,THPO,TPOMKCSF,Thrombopoietin,MKCSF,MGDF...	Mouse	HEK293 Cells
	Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune t...
TMPH-00440	PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His) PRDX1,Thioredoxin-dependent peroxiredoxin 1,Peroxiredoxin-1,...	Chinese hamster	E. coli
	PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-00441	PRDX1 Protein, Cricetulus griseus, Recombinant (His) Thioredoxin peroxidase 2,Thioredoxin-dependent pero...	Chinese hamster	P. pastoris (Yeast)
	PRDX1 Protein, Cricetulus griseus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9JKY1.
TMPY-02843	GPX7 Protein, Human, Recombinant (hFc) GSHPx-7,UNQ469/PRO828,NPGPx,CL683,glutathione peroxidase...	Human	HEK293 Cells
	GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to differ by overlapping exons with different boundaries. GPX7 is an enzyme. It has molecular functions (glutathione peroxidase activity, oxidoreductase activity) and to localize in various compartments (extracellular space, extracellular region). GPX7 gene has been proposed to part...
TMPJ-01098	PRDX4 Protein, Human, Recombinant (His) Prx-IV,Thioredoxin-Dependent Peroxide Reductase A0372,PRDX4,...	Human	E. coli
	Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-...
TMPH-03305	GSTA1 Protein, Rat, Recombinant (His & SUMO) Androst-5-ene-3,17-dione isomerase,GST 1-1,13-hydroperoxyoct...	Rat	E. coli
	GSTA1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His) Antioxidant enzyme B166,Alu corepressor 1,Peroxiredoxin-5,PL...	Human	HEK293 Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/a...
TMPY-05252	Myeloperoxidase/MPO Protein, Human, Recombinant (His) myeloperoxidase	Human	HEK293 Cells
	MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands. Myeloperoxidase (MPO), a specific polymorphonuclear leukocyte enzyme, has ...
TMPY-01736	COX-2 Protein, Human, Recombinant (His) GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-endoperoxide...	Human	Baculovirus Insect Cells
	PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ...
TMPH-03054	Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)	Neosartorya fumigata	E. coli
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Required for virulence.
TMPH-03275	Cytoglobin Protein, Rat, Recombinant (His & Myc) Stellate cell activation-associated protein,Stap,CYGB,Cytogl...	Rat	E. coli
	May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPH-02195	TXNDC17 Protein, Human, Recombinant (GST) Thioredoxin-like protein 5,Protein 42-9-9,Thioredoxin domain...	Human	E. coli
	Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
TMPJ-00690	PGDS Protein, Human, Recombinant Glutathione-Requiring Prostaglandin D Synthase,PGDS,Glutathi...	Human	E. coli
	Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydrop...
TMPH-00072	2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) Thioredoxin-dependent peroxiredoxin BAS1,2-Cys peroxiredoxin...	Arabidopsis thaliana	P. pastoris (Yeast)
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf. 2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96291.
TMPY-02201	Peroxiredoxin 6 Protein, Human, Recombinant (His) p29,PRX,1-Cys,HEL-S-128m,peroxiredoxin 6,NSGPx,AOP2,aiPLA2	Human	E. coli
	PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase (GPx) and iPLA2 activities，which are concomitantly increased with the expression of PRDX6. PRDX6 promoted lung tumor growth in an in vivo allograft...
TMPH-02199	TXNRD2 Protein, Human, Recombinant (His) Thioredoxin-dependent peroxide reductase, mitochondrial,Pero...	Human	E. coli
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. TXNRD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.5 kDa and the accession number is P30048.

重组蛋白

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

Cat.No: TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc)

Cat.No: TMPH-02407

Species: Lentinula edodes

Expression System: E. coli

GPX5 Protein, Pig, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03108

Species: Sus scrofa (Pig)

Expression System: E. coli

GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03443

Species: Saccharomyces cerevisiae

Expression System: E. coli

GPX5 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-01296

Species: Human

Expression System: E. coli

GPX5 Protein, Pig, Recombinant (His & Myc)

Cat.No: TMPH-03109

Species: Sus scrofa (Pig)

Expression System: P. pastoris (Yeast)

GPX7 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02681

Species: Mouse

Expression System: E. coli

Lactoperoxidase/LPO Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01600

Species: Human

Expression System: HEK293 Cells

APX2, cytosolic Protein, Arabidopsis thaliana, Recombinant (His)

Cat.No: TMPH-00096

Species: Arabidopsis thaliana

Expression System: E. coli

Thyroid Peroxidase Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00874

Species: Mouse

Expression System: HEK293 Cells

PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His)

Cat.No: TMPH-00440

Species: Chinese hamster

Expression System: E. coli

PRDX1 Protein, Cricetulus griseus, Recombinant (His)

Cat.No: TMPH-00441

Species: Chinese hamster

Expression System: P. pastoris (Yeast)

GPX7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02843

Species: Human

Expression System: HEK293 Cells

PRDX4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01098

Species: Human

Expression System: E. coli

GSTA1 Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03305

Species: Rat

Expression System: E. coli

PRDX5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00933

Species: Human

Expression System: HEK293 Cells

Myeloperoxidase/MPO Protein, Human, Recombinant (His)

Cat.No: TMPY-05252

Species: Human

Expression System: HEK293 Cells

COX-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01736

Species: Human

Expression System: Baculovirus Insect Cells

Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)

Cat.No: TMPH-03054

Species: Neosartorya fumigata

Expression System: E. coli

Cytoglobin Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03275

Species: Rat

Expression System: E. coli

TXNDC17 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02195

Species: Human

Expression System: E. coli

PGDS Protein, Human, Recombinant

Cat.No: TMPJ-00690

Species: Human

Expression System: E. coli

2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)

Cat.No: TMPH-00072

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

Peroxiredoxin 6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02201

Species: Human

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His)

Cat.No: TMPH-02199

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0278	4-AMinoantipyrine-d3
	4-AMinoantipyrine-d3 是 4-AMinoantipyrine 的氘代化合物。4-AMinoantipyrine 的 CAS 号为 83-07-8。4-Aminoantipyrine是一种检测试剂，在过氧化物酶与苯酚存在时，用于葡萄糖测定。
T71288	Phenylbutazone-d9
	Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 µM in the presence of hydrogen peroxide). It also inhibits prostaglandin I synthase (IC50 = ~25 µM in the presence of hydrogen peroxide). Phenylbutazone (2 mg/kg) reduces increases in type II collagen levels in the inflamed joints of an equine model of LPS-in...

同位素标记化合物

4-AMinoantipyrine-d3

Cat.No: TMID-0278

Phenylbutazone-d9

Cat.No: T71288

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼