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Targets Recommended: Sodium Channel

107

抑制剂 & 化合物

12

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31

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Cat. No. Product Name
L7900 成骨分子库

317 compounds
317 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;

化合物库

成骨分子库
Cat.No: L7900
Compounds: 317
Cat. No. Product Name Target Signaling Pathways
T19644 Benzonatate

Sodium Channel Membrane transporter/Ion channel
Benzonatate 是外周口服镇咳药,对咳嗽延伸受体 (cough stretch receptors) 的活性具有抑制作用。它是丁卡因样代谢物,能够阻断呼吸延伸受体的钠通道并产生局部麻醉作用。
T23070 Nisoxetine hydrochloride

Sodium Channel; Monoamine Transporter; Norepinephrine Membrane transporter/Ion channel; Neuroscience
Nisoxetine hydrochloride 是一种去甲肾上腺素转运蛋白 (NET) 抑制剂,Kd 值为 0.76 nM。它是抗抑郁药和局部麻药,可以阻断电压门控性钠通道。
T1115 Doxylamine succinate

琥珀酸多西拉敏,Decapryn

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Doxylamine succinate (Decapryn) 是一种吡啶衍生物组胺 H1 拮抗剂,具有明显的镇静特性。它竞争性阻断组胺 H1 受体并限制典型的过敏和过敏反应,可防止组胺引起的皮肤和粘膜疼痛和瘙痒。
T0946 Mepivacaine hydrochloride

Mepivacaine HCl,盐酸甲哌卡因

Sodium Channel Membrane transporter/Ion channel
Mepivacaine hydrochloride (Mepivacaine HCl) 是具有局部麻醉特性的酰胺衍生物。Mepivacaine hydrochloride 与神经元细胞膜上特定的电压门控钠离子通道结合,抑制钠离子内流和膜去极化。
T6953 Prilocaine

Citanest,丙胺卡因,Propitocaine,NSC 40027

ATPase; Sodium Channel Membrane transporter/Ion channel
Prilocaine (NSC-40027) 是一种氨基酰胺类局部麻醉剂,作用于神经元膜上的钠通道并限制癫痫发作的扩散。它是Na/K-ATPase 抑制剂,具有神经毒性作用。
T0072 Adiphenine hydrochloride

Adiphenine HCl,盐酸阿地芬宁,Spasnil,Patrovina,Sentiv

AChR Neuroscience
Adiphenine hydrochloride (Patrovina) 是一种烟碱样受体抑制剂,可用作解痉药,对α1、α3β4、α4β2和α4β4的IC50值分别为 1.9、1.8、3.7 和 6.3 µM。
T0916 Butamben

Butyl 4-aminobenzoate,4-氨基苯甲酸丁酯

Potassium Channel; Calcium Channel; Sodium Channel Membrane transporter/Ion channel; Metabolism
Butamben (Butyl 4-aminobenzoate) 是一种长效局部麻醉剂,用于治疗慢性疼痛。
T0796 Prilocaine hydrochloride

Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因

ATPase; Sodium Channel Membrane transporter/Ion channel
Prilocaine hydrochloride (Prilocaine HCl) 是一种氨基酰胺类局部麻醉剂,作用于神经元膜上的钠通道并限制癫痫发作的扩散。它是Na/K-ATPase 抑制剂,具有神经毒性作用。
T13692 Ferric maltol

Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate,麦芽酚铁

Others Others
Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) 是一种具有口服活性的单一铁离子 (Fe3+) 复合物,可用于研究炎症性肠病缺铁性贫血。
T0030 Bupivacaine hydrochloride

Vivacaine,Bupivacaine HCl,盐酸布比卡因

Sodium Channel Membrane transporter/Ion channel
Bupivacaine hydrochloride (Vivacaine) 是NMDA 受体抑制剂,可用于慢性疼痛的研究。它可阻断钠、L-钙和钾通道,还阻断SCN5A 通道,IC50为 69.5 μM。
T19869 Elocalcitol

Ro 26-9228,BXL 628

Others Others
Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.
T124792 Cyclocalopin A

Others Others
Cyclocalopin A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124792。
T0364L Dibucaine hydrochloride

Cinchocaine HCl,Dibucaine HCl,盐酸地布卡因,Cinchocaine hydrochloride

Sodium Channel; AChR Membrane transporter/Ion channel; Neuroscience
Dibucaine hydrochloride (Cinchocaine hydrochloride) 是钠通道抑制剂和有效的 SChE 抑制剂。
T2131 Articaine hydrochloride

Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045

Sodium Channel Membrane transporter/Ion channel
Articaine hydrochloride (Hoe-045) 一种牙科局部麻醉剂。
T0325 Diperodon hydrochloride

盐酸地哌冬,Diothane hydrochloride,Proctodon,Diperocaine

Others Others
Diperodon hydrochloride (Diperocaine) 是一种局部麻醉剂,能够被血清分解酶分解,进而产生局部麻醉作用。
T35009 Vadocaine

Vadocaina,Vadocainum

Others Others
Vadocaine (Vadocaina) 是一种新型的镇咳化合物,可用于局部麻醉,可用于研究中枢神经系统和心血管系统。
T31716L Etidocaine

Others Others
Etidocaine 是一种氨基酸酰胺,用作局部麻醉剂,具有快速起效和长效特性。
T17115 Tolycaine

Others Others
Tolycaine 是一种局部麻醉剂。
T1144L Lidocaine Hydrochloride hydrate

EGFR; Sodium Channel Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
Lidocaine Hydrochloride hydrate 是一种酰胺类局部麻醉剂,具有抗炎作用。
T24451 Mepyramine

NSC-13136,NSC13136,NSC 13136

Others Others
Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally.
T1526 Nifuratel

NF 113,SAP 113,硝呋太尔,Methylmercadone

Antibacterial; Antibiotic; Parasite Microbiology/Virology
Nifuratel (SAP 113) 是广谱抗生素,有抗细菌、真菌和毛滴虫活性。
T1389 Dyclonine hydrochloride

盐酸达克罗宁,Dyclocaine hydrochloride,Dyclonine HCl

Sodium Channel; Antibacterial; Antifungal Membrane transporter/Ion channel; Microbiology/Virology
Dyclonine hydrochloride (Dyclonine HCl) 是润喉片的有效成分,具有显著的杀菌和杀真菌作用。
T6443 Chloroprocaine hydrochloride

盐酸氯普鲁卡因,Chloroprocaine HCl

ATPase; Others Membrane transporter/Ion channel; Others
Chloroprocaine hydrochloride (Chloroprocaine HCl) 是一种 Na/K-ATPase 活性抑制剂,IC50为 13 mM,可阻断外周神经。
T0364 Dibucaine

地布卡因,Cinchocaine

CaMK; Sodium Channel; AChR Membrane transporter/Ion channel; Neuroscience
Dibucaine (Cinchocaine) 是钠通道抑制剂和有效的SChE 抑制剂。
T27572 Ibuprofen diethylaminoethyl ester

Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE

Others Others
Ibuprofen diethylaminoethyl ester (BF DEAE) 具有抗炎活性,可作为局部麻醉剂,可用于研究麻风性神经炎等神经系统疾病。
T13995 1-Methyl-7-nitroisatoic anhydride

1M7

Others Others
1-Methyl-7-nitroisatoic anhydride (1M7) 是一种能够检测局部核苷酸的试剂。
T6566 Levobupivacaine hydrochloride

Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,盐酸左布比卡因,(S)-(-)-Bupivacaine monohydrochloride

Sodium Channel Membrane transporter/Ion channel
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) 是有效的钠通道阻滞剂。
T28829 Soquinolol

Soquinolol mucate

Adrenergic Receptor GPCR/G Protein; Neuroscience
Soquinolol (Soquinolol mucate) 是一种β肾上腺素能受体拮抗剂,具有较弱的局部麻醉活性。Soquinolol 具有良好的肠内疗效和较长的作用持续时间。
T21444 Diphenylcyclopropenone

DPCP,Diphencyprone,二苯基环丙烯酮

Others Others
Diphenylcyclopropenone (DPCP) 是局部免疫调节剂,可用于研究斑秃。
T13830 Propoxycaine hydrochloride

Propoxycaine HCl

Sodium Channel Membrane transporter/Ion channel
Propoxycaine hydrochloride 是一种酯类局部麻醉剂,抑制电压门控的钠通道,可调节神经冲动,可诱导感觉丧失。Propoxycaine hydrochloride 可调节SPMVs脂质双层的流动。
T7118 Dimethocaine

二甲卡因,Larocaine

Others; Dopamine Receptor GPCR/G Protein; Neuroscience; Others
Dimethocaine (Larocaine) 是一种局部麻醉剂,也对中枢神经系统起多巴胺再摄取抑制剂的作用。
T0328 Hexetidine

NSC-17764,海克替啶

Antibacterial; Antifungal Microbiology/Virology
Hexetidine (NSC-17764) 是一种口服活性的抗菌抗真菌试剂,可用于口腔感染的相关研究。
T68165 Trapencaine

Others Others
Trapencaine 是一种新合成的氨基甲酸型局部麻醉剂,诱导的肥大细胞膜上钠通道的构象变化。
T0378 Oxybuprocaine hydrochloride

Risedronic Acid,Oxybuprocaine HCl,奥布卡因盐酸盐

Sodium Channel Membrane transporter/Ion channel
Oxybuprocaine hydrochloride (Oxybuprocaine HCl) 是可逆的钠通道阻断剂,可防止角膜,结膜和巩膜中疼痛神经的冲动传播。Oxybuprocaine hydrochloride 专用于眼科与耳鼻喉科。
T0726 Benzydamine hydrochloride

Benzydamine HCl,盐酸苄达明,AF864

COX; PGE Synthase; Antibacterial Immunology/Inflammation; Microbiology/Virology; Neuroscience
Benzydamine hydrochloride (AF864) 是一种局部作用的非甾体抗炎药,具有局部麻醉和镇痛作用。它也是前列腺素合成酶抑制剂,有抗细菌活性。
T14038L 4-Azido-L-phenylalanine hydrochloride

p-Azido-L-phenylalanine hydrochloride,p-Azidophenylalanine hydrochloride

Others Others
4-Azido-L-phenylalanine hydrochloride (p-Azido-L-phenylalanine hydrochloride) 是非天然氨基酸,可有效振动报道蛋白质环境。
T1198 Tetracaine hydrochloride

盐酸丁卡因,Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl

Calcium Channel; Sodium Channel Membrane transporter/Ion channel; Metabolism
Tetracaine hydrochloride (Amethocalne HCl) 是一种钙通道蛋白抑制剂,可阻断肌浆网中 Ca2+的电压敏感释放。它主要用作眼科的止痒剂和局部用药,可用于表面和脊髓麻醉。
T27397 Gacyclidine

GK 11,OTO311,OTO-311,OTO 311,GK-11

NMDAR Neuroscience
Gacyclidine (OTO311) 是一种小分子 N-甲基-D-天冬氨酸(NMDA)受体拮抗剂。在耳蜗局部注射加西环定可抑制水杨酸盐引起的耳鸣,可用于治疗脑损伤、脊髓损伤和耳鸣。
TP1820L Osteogenic Growth Peptide, OGP acetate

Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base)

Others Others
Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base) 是一种短的、天然存在的 14 聚体生长因子肽,存在于血清中,浓度为 μM。成骨生长肽 OGP 是局部骨髓损伤全身成骨反应机制的关键因素。
T34383L 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv

Others Others
2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv在Sprague Dawley大鼠上进行测试时显示出高局部抗炎效力和高肺选择性。
T0386 Ropivacaine hydrochloride

盐酸罗哌卡因,Ropivacaine monohydrochloride

Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) 是钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine hydrochloride 也是 K2P(双孔钾通道)TREK-1的抑制剂。在动物实验模型中,Ropivacaine hydrochloride 可用于神经性疼痛的缓解。
T1787 Levobupivacaine

Sodium Channel Membrane transporter/Ion channel
Levobupivacaine 是一种氨基酰胺类局麻药,属于n-alkylsubstituted pipecoloxylidide 家族。它是bupivacaine 的 S-对映异构体。
T0386L Ropivacaine

LEA-103 HCl,罗哌卡因

Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Ropivacaine (LEA-103 HCl) 是有效的钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂,在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
T0029 Procaine

Duracaine,Spinocaine,普鲁卡因,Novocaine,Vitamin H3,奴夫卡因

Histone Demethylase; DNA/RNA Synthesis; Sodium Channel Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel
Procaine (Vitamin H3) 是DNA 脱甲基剂,是一种酯类局部麻醉剂。它起效缓慢,作用持续时间短,主要用于浸润麻醉、周围神经阻滞和脊髓阻滞。
T0222 Proparacaine hydrochloride

盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride

Apoptosis; Sodium Channel Apoptosis; Membrane transporter/Ion channel
Proparacaine hydrochloride (Proparacaine HCl) 是 Lidocaine 的衍生物,具有糖皮质激素样活性和免疫调节作用。
T1144 Lidocaine hydrochloride

Lidocaine HCL,盐酸利多卡因,Lignocaine hydrochloride,Xyloneural,Lidothesin

Apoptosis; ERK; NF-κB; MEK; Sodium Channel Apoptosis; MAPK; Membrane transporter/Ion channel; NF-κB
Lidocaine hydrochloride (Lignocaine hydrochloride) 抑制涉及复杂电压和依赖性的钠通道。它通过调节 miR-145 表达和进一步抑制 MEK/ERK 和 NF-κB 信号通路来减少胃癌细胞的生长,迁移和侵袭。Lidocaine 是一种酰胺衍生物,是一种研究室性心律失常的药物和有效的肿瘤抑制剂。
T22361 Mepivacaine

Carbocaine

Sodium Channel Membrane transporter/Ion channel
Mepivacaine (Carbocaine) 是一种可用于局部麻醉的酰胺类化合物,可使人或动物短暂的失去自知觉。Mepivacaine 通过与神经细胞膜上特定的电压门控钠离子通道结合,抑制钠离子内流和膜去极化来发挥作用。Mepivacaine 适用于神经阻滞和硬膜外麻醉。
T0901 Chlorobutanol

Chlortran,Chloretone,YM-57158,三氯叔丁醇,Chlorbutol,Chloreton

Antibacterial; Antibiotic; Antifungal Microbiology/Virology
Chlorobutanol (Chlortran) 是一种药物防腐剂,对多种革兰氏阳性和革兰氏阴性细菌以及几种霉菌孢子和真菌具有抗性。它广泛用于食品和化妆品工业,有促进安定、睡眠的作用。
T15259 Evatanepag

CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂,可诱导局部骨形成,EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。
T1232 Mepyramine maleate

马来酸吡纳明,Pyrilamine maleate,吡拉明马来酸盐

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mepyramine maleate (Pyrilamine maleate) 是一种组胺 H1 拮抗剂,对 H1、H2 和 H3 受体的 Kd 值分别为 0.8、5200 和大于 3000 nM,对 H1 受体的 pKd 值为 9.4。它是感冒药的常见成分,具有温和的催眠特性和局部麻醉作用,可用于胃肠外和局部过敏。

化合物

Benzonatate
Cat.No: T19644
Synonym:
Target: Sodium Channel
Nisoxetine hydrochloride
Cat.No: T23070
Synonym:
Target: Sodium Channel, Monoamine Transporter, Norepinephrine
Doxylamine succinate
Cat.No: T1115
Synonym: 琥珀酸多西拉敏,Decapryn
Target: Histamine Receptor
Mepivacaine hydrochloride
Cat.No: T0946
Synonym: Mepivacaine HCl,盐酸甲哌卡因
Target: Sodium Channel
Prilocaine
Cat.No: T6953
Synonym: Citanest,丙胺卡因,Propitocaine,NSC 40027
Target: ATPase, Sodium Channel
Adiphenine hydrochloride
Cat.No: T0072
Synonym: Adiphenine HCl,盐酸阿地芬宁,Spasnil,Patrovina,Sentiv
Target: AChR
Butamben
Cat.No: T0916
Synonym: Butyl 4-aminobenzoate,4-氨基苯甲酸丁酯
Target: Potassium Channel, Calcium Channel, Sodium Channel
Prilocaine hydrochloride
Cat.No: T0796
Synonym: Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因
Target: ATPase, Sodium Channel
Ferric maltol
Cat.No: T13692
Synonym: Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate,麦芽酚铁
Target: Others
Bupivacaine hydrochloride
Cat.No: T0030
Synonym: Vivacaine,Bupivacaine HCl,盐酸布比卡因
Target: Sodium Channel
Elocalcitol
Cat.No: T19869
Synonym: Ro 26-9228,BXL 628
Target: Others
Cyclocalopin A
Cat.No: T124792
Synonym:
Target: Others
Dibucaine hydrochloride
Cat.No: T0364L
Synonym: Cinchocaine HCl,Dibucaine HCl,盐酸地布卡因,Cinchocaine hydrochloride
Target: Sodium Channel, AChR
Articaine hydrochloride
Cat.No: T2131
Synonym: Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045
Target: Sodium Channel
Diperodon hydrochloride
Cat.No: T0325
Synonym: 盐酸地哌冬,Diothane hydrochloride,Proctodon,Diperocaine
Target: Others
Vadocaine
Cat.No: T35009
Synonym: Vadocaina,Vadocainum
Target: Others
Etidocaine
Cat.No: T31716L
Synonym:
Target: Others
Tolycaine
Cat.No: T17115
Synonym:
Target: Others
Lidocaine Hydrochloride hydrate
Cat.No: T1144L
Synonym:
Target: EGFR, Sodium Channel
Mepyramine
Cat.No: T24451
Synonym: NSC-13136,NSC13136,NSC 13136
Target: Others
Nifuratel
Cat.No: T1526
Synonym: NF 113,SAP 113,硝呋太尔,Methylmercadone
Target: Antibacterial, Antibiotic, Parasite
Dyclonine hydrochloride
Cat.No: T1389
Synonym: 盐酸达克罗宁,Dyclocaine hydrochloride,Dyclonine HCl
Target: Sodium Channel, Antibacterial, Antifungal
Chloroprocaine hydrochloride
Cat.No: T6443
Synonym: 盐酸氯普鲁卡因,Chloroprocaine HCl
Target: ATPase, Others
Dibucaine
Cat.No: T0364
Synonym: 地布卡因,Cinchocaine
Target: CaMK, Sodium Channel, AChR
Ibuprofen diethylaminoethyl ester
Cat.No: T27572
Synonym: Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE
Target: Others
1-Methyl-7-nitroisatoic anhydride
Cat.No: T13995
Synonym: 1M7
Target: Others
Levobupivacaine hydrochloride
Cat.No: T6566
Synonym: Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,盐酸左布比卡因,(S)-(-)-Bupivacaine monohydrochloride
Target: Sodium Channel
Soquinolol
Cat.No: T28829
Synonym: Soquinolol mucate
Target: Adrenergic Receptor
Diphenylcyclopropenone
Cat.No: T21444
Synonym: DPCP,Diphencyprone,二苯基环丙烯酮
Target: Others
Propoxycaine hydrochloride
Cat.No: T13830
Synonym: Propoxycaine HCl
Target: Sodium Channel
Dimethocaine
Cat.No: T7118
Synonym: 二甲卡因,Larocaine
Target: Others, Dopamine Receptor
Hexetidine
Cat.No: T0328
Synonym: NSC-17764,海克替啶
Target: Antibacterial, Antifungal
Trapencaine
Cat.No: T68165
Synonym:
Target: Others
Oxybuprocaine hydrochloride
Cat.No: T0378
Synonym: Risedronic Acid,Oxybuprocaine HCl,奥布卡因盐酸盐
Target: Sodium Channel
Benzydamine hydrochloride
Cat.No: T0726
Synonym: Benzydamine HCl,盐酸苄达明,AF864
Target: COX, PGE Synthase, Antibacterial
4-Azido-L-phenylalanine hydrochloride
Cat.No: T14038L
Synonym: p-Azido-L-phenylalanine hydrochloride,p-Azidophenylalanine hydrochloride
Target: Others
Tetracaine hydrochloride
Cat.No: T1198
Synonym: 盐酸丁卡因,Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl
Target: Calcium Channel, Sodium Channel
Gacyclidine
Cat.No: T27397
Synonym: GK 11,OTO311,OTO-311,OTO 311,GK-11
Target: NMDAR
Osteogenic Growth Peptide, OGP acetate
Cat.No: TP1820L
Synonym: Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base)
Target: Others
2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv
Cat.No: T34383L
Synonym:
Target: Others
Ropivacaine hydrochloride
Cat.No: T0386
Synonym: 盐酸罗哌卡因,Ropivacaine monohydrochloride
Target: Potassium Channel, Sodium Channel
Levobupivacaine
Cat.No: T1787
Synonym:
Target: Sodium Channel
Ropivacaine
Cat.No: T0386L
Synonym: LEA-103 HCl,罗哌卡因
Target: Potassium Channel, Sodium Channel
Procaine
Cat.No: T0029
Synonym: Duracaine,Spinocaine,普鲁卡因,Novocaine,Vitamin H3,奴夫卡因
Target: Histone Demethylase, DNA/RNA Synthesis, Sodium Channel
Proparacaine hydrochloride
Cat.No: T0222
Synonym: 盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride
Target: Apoptosis, Sodium Channel
Lidocaine hydrochloride
Cat.No: T1144
Synonym: Lidocaine HCL,盐酸利多卡因,Lignocaine hydrochloride,Xyloneural,Lidothesin
Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel
Mepivacaine
Cat.No: T22361
Synonym: Carbocaine
Target: Sodium Channel
Chlorobutanol
Cat.No: T0901
Synonym: Chlortran,Chloretone,YM-57158,三氯叔丁醇,Chlorbutol,Chloreton
Target: Antibacterial, Antibiotic, Antifungal
Evatanepag
Cat.No: T15259
Synonym: CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸
Target: Prostaglandin Receptor
Mepyramine maleate
Cat.No: T1232
Synonym: 马来酸吡纳明,Pyrilamine maleate,吡拉明马来酸盐
Target: Histamine Receptor
Cat. No. Product Name Target Signaling Pathways
T0314 Hexylresorcinol

己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol

Apoptosis; Tyrosinase; Antibacterial; Parasite Apoptosis; Microbiology/Virology; Proteases/Proteasome
Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物,具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂,有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。
TN4684 O-Acetylcyclocalopin A

Others Others
O-Acetylcyclocalopin A是一种天然产物,其产品编号为 TN4684,CAS号为 486430-93-7。O-Acetylcyclocalopin A可用作对照参考。
T0012 Cinchonine

LA40221,(8R,9S)-Cinchonine,奎宁树,辛可宁

Apoptosis; P-gp; Parasite Apoptosis; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Cinchonine (LA40221) 是金鸡纳树皮中的一种天然产物。它可激活内质网应激诱导的人肝癌细胞凋亡。它是一种酰胺类局部麻醉剂。
T1407 (-)-Menthol

L-Menthol,Levomenthol,(-)-薄荷醇,薄荷冰,Menthomenthol,Menthacamphor

Opioid Receptor; Endogenous Metabolite; TRP/TRPV Channel Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
(-)-Menthol (Levomenthol) 分离自薄荷油,L-Menthol 是瞬时受体电位 M8 (TRPM8)的激活剂,TRPM8 是 Ca2+-可渗透的非选择性阳离子通道,并增加 [Ca2+]i。L-Menthol 具有抗肿瘤活性。
T5S1550 Cinnamyl alcohol

肉桂醇,肉桂醇;beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol

PPAR DNA Damage/DNA Repair; Metabolism
Cinnamyl alcohol (Styryl Carbinol) 是从板栗花中分离得到的一种活性成分,抑制增加的 PPARγ表达,具有抗肥胖作用。
T0043 Octodrine

二甲己胺,2-Amino-6-methylheptane,6-Methyl-2-heptylamine,1,5-Dimethylhexylamine

Dopamine Receptor GPCR/G Protein; Neuroscience
Octodrine (2-Amino-6-methylheptane) 是一种中枢神经刺激剂,可增加痛阈、心率 (正变时效应) 和心肌收缩力 (正变力效应),可增加多巴胺和去甲肾上腺素 (noradrenaline) 的摄取。
T5723 Menthol

薄荷脑,DL-Menthol

Others; Calcium Channel Membrane transporter/Ion channel; Metabolism; Others
Menthol (DL-Menthol) 是从薄荷或薄荷油中得到的一种天然产物,具有调味和局部麻醉特性。它通过抑制神经元细胞膜的 Ca++电流,刺激冷感受器,从而产生清凉的感觉。
T1301 Guaiacol

O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚

NF-κB; COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Guaiacol (2-Methoxyphenol) 是从小叶栲中提取的一种酚类,可抑制 LPS 刺激的COX-2表达和NF-κB 激活,具有抗炎活性。
T3893 Forsythoside B

连翘酯苷 B,连翘脂苷B

TNF; NF-κB Apoptosis; NF-κB
Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha,IL-6,IκB, 调节 NF-κB。它抑制炎症反应,具有抗氧化和神经保护作用。
TN6028 Gardneramine

Gardneramine has a mild central depressive effect. Gardneramine and hirsutine show a local anesthetic action, they also can inhibit the ganglionic transmission of the dog urinary bladder and that the blockade of the nicotinic receptor plays a main role.
T35770 Cylindrospermopsin

Others Others
Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &#181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &...
T36489 Malformin A

Others Others
Malformin A is a cyclopentapeptide fungal metabolite that has been found in A. niger and has diverse biological activities. It is a plant growth regulator that induces malformations in plant structure. Malformin A inhibits replication of tobacco mosaic virus (TMV) in local lesion and leaf-disc assays (IC50s = 19.7 and 45.4 μg/ml, respectively). It is cytotoxic to NCI-H460, MIA PaCa-2, MCF-7, SF-268, and WI-38 cancer cells (IC50s = 70, 50, 100, 70, and 100 nM, respectively), inhibits proliferati...

天然产物

Hexylresorcinol
Cat.No: T0314
Synonym: 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol
Target: Apoptosis, Tyrosinase, Antibacterial, Parasite
O-Acetylcyclocalopin A
Cat.No: TN4684
Synonym:
Target: Others
Cinchonine
Cat.No: T0012
Synonym: LA40221,(8R,9S)-Cinchonine,奎宁树,辛可宁
Target: Apoptosis, P-gp, Parasite
(-)-Menthol
Cat.No: T1407
Synonym: L-Menthol,Levomenthol,(-)-薄荷醇,薄荷冰,Menthomenthol,Menthacamphor
Target: Opioid Receptor, Endogenous Metabolite, TRP/TRPV Channel
Cinnamyl alcohol
Cat.No: T5S1550
Synonym: 肉桂醇,肉桂醇;beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol
Target: PPAR
Octodrine
Cat.No: T0043
Synonym: 二甲己胺,2-Amino-6-methylheptane,6-Methyl-2-heptylamine,1,5-Dimethylhexylamine
Target: Dopamine Receptor
Menthol
Cat.No: T5723
Synonym: 薄荷脑,DL-Menthol
Target: Others, Calcium Channel
Guaiacol
Cat.No: T1301
Synonym: O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚
Target: NF-κB, COX, Endogenous Metabolite
Forsythoside B
Cat.No: T3893
Synonym: 连翘酯苷 B,连翘脂苷B
Target: TNF, NF-κB
Gardneramine
Cat.No: TN6028
Synonym:
Target:
Cylindrospermopsin
Cat.No: T35770
Synonym:
Target: Others
Malformin A
Cat.No: T36489
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-00086 Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His)

reticulocalbin 3, EF-hand calcium binding domain

Rat HEK293 Cells
Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is I6L9G5.
TMPH-02030 Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His)

Reticulocalbin-1,RCN1

Human P. pastoris (Yeast)
Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPY-04672 Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His)

D530026G20Rik,6030455P07Rik,D7Ertd671e,RLP49,reticulocal...

Mouse HEK293 Cells
Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.9 kDa and the accession number is Q8BH97.
TMPY-03181 Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His)

RLP49,reticulocalbin 3, EF-hand calcium binding dom...

Human HEK293 Cells
Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q96D15.
TMPH-01355 FXR1 Protein, Human, Recombinant (His)

FXR1,RNA-binding protein FXR1,FMR1 autosomal homolog 1,hFXR1...

Human E. coli
RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. FXR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 70.5 kDa and the accession number is P51114.
TMPH-02227 ERG Protein, Human, Recombinant (His)

Transcriptional regulator ERG,Transforming protein ERG,ERG

Human P. pastoris (Yeast)
Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. ERG Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 56.6 kDa and the accession number is P11308.
TMPJ-00623 BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)

Tumor necrosis factor ligand 7A,TNF superfamily member 13b,T...

Rhesus HEK293 Cells
TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules in local and systemic inflammatory network, and the plasma TNFSF13B and TNFSF14 may be the potential local and systemic inflammatory indicators of severe HAdV pneumonia in pediatric patients. Identification of TNFSF13B as candidate causative genes supports conjectures on involvement of the immune system in BVVL and amyotrophic lateral s...
TMPH-01559 IL-26 Protein, Human, Recombinant (His)

Protein AK155,Interleukin-26,IL26

Human P. pastoris (Yeast)
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecula...
TMPH-03097 Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc)

Beta-elicitin cryptogein,CRY

Phytophthora cryptogea E. coli
Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families. Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins. Might interact with the lipidic molecules of the plasma membrane. Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.3 kDa and the accession...
TMPH-01560 IL-26 Protein, Human, Recombinant (His & Trx)

Interleukin-26,Protein AK155,IL26

Human E. coli
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with N-6xHis-T...
TMPH-00985 NPR3 Protein, Human, Recombinant (His)

Atrial natriuretic peptide receptor type C,Atrial natriureti...

Human E. coli
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-...
TMPJ-01349 SEMA4B Protein, Human, Recombinant (His)

SEMAC and SEMA4B,KIAA1745,Semaphorin-4B

Human HEK293 Cells
The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
TMPH-03250 NPR3 Protein, Rat, Recombinant (His & SUMO)

Npr3,Atrial natriuretic peptide receptor 3,Atrial natriureti...

Rat E. coli
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system wi...
TMPH-03107 Complement C5a Protein, Pig, Recombinant (His)

Complement C5a anaphylatoxin,C5

Sus scrofa (Pig) P. pastoris (Yeast)
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation....
TMPJ-00878 NPR3 Protein, Human, Recombinant (hFc)

ANPRC,ANPR-C,C5orf23,NPR-C,NPRC,NPR3,ANP-C

Human HEK293 Cells
Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for N...
TMPJ-01348 SEMA4B Protein, Human, Recombinant (hFc & His)

SEMAC,Semaphorin-4B,KIAA1745,SEMA4B

Human HEK293 Cells
Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for gr...
TMPJ-01169 SEMA4A Protein, Mouse, Recombinant (His)

Semaphorin-4A,Semaphorin-B,Semab,Sema B,Sema4a,SemB

Mouse HEK293 Cells
Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 10 in the embryo, and low levels are found between days 10-12. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. It plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A ...
TMPJ-00012 CXCL4 Protein, Human, Recombinant (His)

SCYB4,PF4,Iroplact,Platelet Factor 4,PF-4,Oncostatin-A,CXCL4...

Human HEK293 Cells
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokin...
TMPY-03117 Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)

ZAG,α-2-glycoprotein 1, zinc-binding,Zinc α 2,ZA2G,alpha-2-g...

Human HEK293 Cells
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malign...
TMPJ-00402 CD117 Protein, Human, Recombinant (hFc)

KIT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...

Human HEK293 Cells
C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing sti...
TMPJ-01237 IL-17D Protein, Human, Recombinant

IL17D,Interleukin-17D,IL-17D

Human E. coli
The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence ho...
TMPJ-00253 OPG Protein, Mouse, Recombinant (His)

Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhibitory factor,Oste...

Mouse HEK293 Cells
Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ...
TMPY-02979 HMGN3 Protein, Human, Recombinant (His)

PNAS-24,TRIP7,PNAS-25,high mobility group nucleosomal bindin...

Human E. coli
HMGN3 belongs to the HMGN family and is expressed in the kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate, and uterus. Members of the HMGN family bind to nucleosomes without any specificity for the underlying DNA sequence. They affect the global and local structure of chromatin, as well as the levels of histone modifications, and thus play a role in epigenetic regulation of gene expression. HMGN3 regulates the expression of the glucose transporter ...
TMPY-02125 CCL6 Protein, Mouse, Recombinant (His)

Scya6,MRP-1,c10,RP23-320E6.4,chemokine (C-C motif) ligand 6

Mouse HEK293 Cells
Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is involved in the chronic stages of host defense reactions. C10 chemokine rapidly promotes disease resolution in the cecal ligation and puncture (CLP) model through its direct effects on the cellular events critically involved in host defense during septic peritonitis. CCL6 appears ...
TMPY-00741 CXCL4 Protein, Human, Recombinant

PF-4,platelet factor 4,SCYB4,CXCL4

Human E. coli
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils a...
TMPY-00821 HGFA Protein (pro form), Human, Recombinant (His)

MGC138397,HGFA,RP11-529E1.2,肝细胞生长因子,MGC138395

Human HEK293 Cells
HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is clea...
TMPY-02574 Chymase 1 Protein, Human, Recombinant (His)

MCT1,chymase 1, mast cell,chymase,CYH

Human Baculovirus Insect Cells
The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II system (LAS) has numerous functions, including the regulation of growth and differentiation in the gastrointestinal tract. Angiotensin II (AngII) may be generated by angiotensin-I-converting enzyme (ACE) or mast cell chymase (CMA1) and plays an important role in inflammatory process...
TMPH-03426 Rotavirus X (isolate novel adult diarrhea rotavirus-B219) VP4 Protein (His)

Hemagglutinin,Outer capsid protein VP4

RVX P. pastoris (Yeast)
Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. It is subsequently lost, together with VP7, following virus entry into the host cell. Following entry into the host cell, low intracellular o...
TMPY-02163 PGLYRP1 Protein, Mouse, Recombinant (His)

Tnfsf3l,peptidoglycan recognition protein 1,PGRP,Tasg7,Tag7,...

Mouse HEK293 Cells
Peptidoglycan recognition protein 1, also known as Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP and TNFSF3L, is a secreted protein that belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 / PGLYRP is highly expressed in bone marrow. It is weakly expressed in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. PGLYRP1 / PGLYRP is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-posi...
TMPJ-00060 IL-25/IL17E Protein, Human, Recombinant (His)

白细胞介素,IL17E,白介素,IL-17E,IL-25,IL25,Interleukin-25,Interleukin...

Human HEK293 Cells
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator...
TMPY-00975 FSTL3 Protein, Mouse, Recombinant (His)

E030038F23Rik,Flrg,follistatin-like 3 (secreted glycoprotein...

Mouse HEK293 Cells
Follistatin-like 3 (FLRG/Fstl3) is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis. FLRG/Fstl3 is a recently described member of the FST family having an overall structure and activity profile similar to that of FST, including binding and neutralization of activin. FLRG/Fstl3 is expressed in a wide range of adult tissues, not detected in hematopoietic cells except in patients with a B cell chronic leukemia and a translocation. Isoform 1 or t...

重组蛋白

Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-00086
Species: Rat
Expression System: HEK293 Cells
Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02030
Species: Human
Expression System: P. pastoris (Yeast)
Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04672
Species: Mouse
Expression System: HEK293 Cells
Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03181
Species: Human
Expression System: HEK293 Cells
FXR1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01355
Species: Human
Expression System: E. coli
ERG Protein, Human, Recombinant (His)
Cat.No: TMPH-02227
Species: Human
Expression System: P. pastoris (Yeast)
BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00623
Species: Rhesus
Expression System: HEK293 Cells
IL-26 Protein, Human, Recombinant (His)
Cat.No: TMPH-01559
Species: Human
Expression System: P. pastoris (Yeast)
Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc)
Cat.No: TMPH-03097
Species: Phytophthora cryptogea
Expression System: E. coli
IL-26 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPH-01560
Species: Human
Expression System: E. coli
NPR3 Protein, Human, Recombinant (His)
Cat.No: TMPH-00985
Species: Human
Expression System: E. coli
SEMA4B Protein, Human, Recombinant (His)
Cat.No: TMPJ-01349
Species: Human
Expression System: HEK293 Cells
NPR3 Protein, Rat, Recombinant (His & SUMO)
Cat.No: TMPH-03250
Species: Rat
Expression System: E. coli
Complement C5a Protein, Pig, Recombinant (His)
Cat.No: TMPH-03107
Species: Sus scrofa (Pig)
Expression System: P. pastoris (Yeast)
NPR3 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00878
Species: Human
Expression System: HEK293 Cells
SEMA4B Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-01348
Species: Human
Expression System: HEK293 Cells
SEMA4A Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01169
Species: Mouse
Expression System: HEK293 Cells
CXCL4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00012
Species: Human
Expression System: HEK293 Cells
Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03117
Species: Human
Expression System: HEK293 Cells
CD117 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00402
Species: Human
Expression System: HEK293 Cells
IL-17D Protein, Human, Recombinant
Cat.No: TMPJ-01237
Species: Human
Expression System: E. coli
OPG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00253
Species: Mouse
Expression System: HEK293 Cells
HMGN3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02979
Species: Human
Expression System: E. coli
CCL6 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02125
Species: Mouse
Expression System: HEK293 Cells
CXCL4 Protein, Human, Recombinant
Cat.No: TMPY-00741
Species: Human
Expression System: E. coli
HGFA Protein (pro form), Human, Recombinant (His)
Cat.No: TMPY-00821
Species: Human
Expression System: HEK293 Cells
Chymase 1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02574
Species: Human
Expression System: Baculovirus Insect Cells
Rotavirus X (isolate novel adult diarrhea rotavirus-B219) VP4 Protein (His)
Cat.No: TMPH-03426
Species: RVX
Expression System: P. pastoris (Yeast)
PGLYRP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02163
Species: Mouse
Expression System: HEK293 Cells
IL-25/IL17E Protein, Human, Recombinant (His)
Cat.No: TMPJ-00060
Species: Human
Expression System: HEK293 Cells
FSTL3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00975
Species: Mouse
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIJ-0246 Tetracaine-d6

Tetracaine-d6 是 Tetracaine 的氘代化合物。Tetracaine 的 CAS 号为 94-24-6。
TMID-0185 (±)-Ropivacaine-d7

(±)-Ropivacaine-d7 是 (±)-Ropivacaine 的氘代化合物。(±)-Ropivacaine 的 CAS 号为 84057-95-4。Ropivacaine 是有效的钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂,在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
TMIJ-0102 Ropivacaine-d7

Ropivacaine-d7 是 Ropivacaine 的氘代化合物。Ropivacaine 的 CAS 号为 84057-95-4。Ropivacaine 是有效的钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂,在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
TMIJ-0228 Lidocaine-d6 HCl

Lidocaine-d6 HCl 是 Lidocaine HCl 的氘代化合物。Lidocaine HCl 的 CAS 号为 73-78-9。Lidocaine hydrochloride 抑制涉及复杂电压和依赖性的钠通道。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。Lidocaine 是一种酰胺衍生物,是一种研究室性心律失常的药物和有效的肿瘤抑制剂。
TMID-0263 Lidocaine-d10 Hydrochloride

Lidocaine-d10 Hydrochloride 是 Lidocaine Hydrochloride 的氘代化合物。Lidocaine Hydrochloride 的 CAS 号为 73-78-9。Lidocaine hydrochloride 抑制涉及复杂电压和依赖性的钠通道。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。Lidocaine 是一种酰胺衍生物,是一种研究室性心律失常的药物和有效的肿瘤抑制剂。
TMID-0262 Lidocaine-d10 (N,N-diethyl-d10)

Lidocaine-d10 (N,N-diethyl-d10) 是 Lidocaine 的氘代化合物。Lidocaine 的 CAS 号为 137-58-6。Lidocaine是一种酰胺衍生物,抑制涉及复杂电压和依赖性的钠通道,可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。

同位素标记化合物

Tetracaine-d6
Cat.No: TMIJ-0246
Synonym:
Target:
(±)-Ropivacaine-d7
Cat.No: TMID-0185
Synonym:
Target:
Ropivacaine-d7
Cat.No: TMIJ-0102
Synonym:
Target:
Lidocaine-d6 HCl
Cat.No: TMIJ-0228
Synonym:
Target:
Lidocaine-d10 Hydrochloride
Cat.No: TMID-0263
Synonym:
Target:
Lidocaine-d10 (N,N-diethyl-d10)
Cat.No: TMID-0262
Synonym:
Target:
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