417
128
4
80
9
Cat. No. | Product Name | ||
---|---|---|---|
L1310 | 细胞骨架化合物库 | 759 compounds | |
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选; | |||
L2570 | 人代谢物化合物库 | 4454 compounds | |
4454 种人代谢物的独特集合,用于高通量、高内涵筛选; | |||
L6030 | 天然产物衍生物虚筛化合物库 | 163000 compounds | |
16.3万种天然产物衍生物,并且在持续增加中; | |||
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8753 |
LX-2761 intermediate
|
Others | Others |
LX-2761 intermediate 是LX-2761的合成中间体。LX-2761是一种化学稳定且有效的SGLT1/2抑制剂。 | |||
T8750 |
LX-4211 intermediate
|
Others | Others |
LX-4211 intermediate 是LX-4211的合成中间体。LX-4211是有效的SGLT1/2抑制剂,用作抗糖尿病剂。 | |||
T10884 |
CRAC intermediate 1
5-(S)-Fluorowillardiine |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
CRAC intermediate 1是用于CRAC离子通道系列化合物合成的关键中间体,详细信息来自专利WO 2010122089。 | |||
T10885 |
CRAC intermediate 2
|
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
CRAC intermediate 2是CRAC 抑制剂合成的中间体化合物。 | |||
T5903 |
Sitagliptin Intermediate 2
|
Others | Others |
Sitagliptin Intermediate 2 是有一种有用的有机化合物,已被用于生命科学相关研究。 | |||
T11074 |
Dolutegravir intermediate-1
1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) 是 Dolutegravir 的一种新合成中间体。 它是一种整合酶抑制剂,有潜力研究人类免疫缺陷病毒 (HIV)-1 感染。 | |||
T22249 |
1588-A4
ARS-1620 Intermediate |
Ras | GPCR/G Protein; MAPK |
1588-A4 (ARS-1620 Intermediate) 是 ARS-1620 的中间体,ARS-1620 是一种具有理想药代动力学的阻转异构选择性 KRASG12C 抑制剂。 | |||
T83968 |
20-HETE Intermediate 15
Methyl (5Z,8Z,11Z,14Z)-20-(acetyloxy)-5,8,11,14-eicosatetraenoate |
||
20-HETE Intermediate 15 是20-羟基二十碳四烯酸的中间体。 | |||
T67152 |
Dacomitinib Intermediate 2
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine |
Others | Others |
Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) 具有抗癌活性,可用于研究肺癌。 | |||
T66121 |
Ketoconazole Intermediate 1e
(cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate |
Others | Others |
Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate) 是一种酮康唑中间体。 | |||
T9562 |
Type III-Intermediate 8
|
Others | Others |
Type III-Intermediate 8 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T9562。 | |||
T65554 |
cholesterol-absorption inhibitor Intermediate 2
|
Others | Others |
cholesterol-absorption inhibitor Intermediate 2 是一种有效且具有口服活性的胆固醇吸收抑制剂,可降低血液中胆固醇含量。 | |||
TP1874 |
Alisporivir intermediate-1
|
||
Alisporivir intermediate-1 is a crucial intermediate compound utilized in the synthesis process of Alisporivir, a therapeutic agent employed for the treatment of inflammatory and viral ailments. | |||
T10028 |
PDE4 inhibitor intermediate 1
|
Others | Others |
PDE4 inhibitor intermediate 1 is a PDE4 inhibitor synthesis intermediate. | |||
T3450 |
LX4211 N-4 Intermediate 9
索格列净中间体9,Sotagliflozin Intermediate 9 |
||
LX4211 N-4 Intermediate 9 是 Sotagliflozin 的中间体,Sotagliflozin 是一种口服生物可利用的 SGLT1 和 SGLT2 抑制剂。 | |||
T22595 |
B2
Linazolamide intermediate B impurity 2,CPNQ,5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline,奥司他韦杂质B(2-叠氮杂合物) |
Others; Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair; Others |
B2 (Linazolamide intermediate B impurity 2) 促进亨廷顿病和帕金森病细胞模型中的包涵体形成。 | |||
T16795 |
Rpn11-IN-1
Capzimin intermediate |
Others | Others |
Rpn11-IN-1 is an effective and selective inhibitor of proteasome subunit Rpn11 (IC50: 390 nM). | |||
T84827 |
SC209 intermediate-1
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
SC209 intermediate-1(Compound A7a)为ADC连接子,用于ADC合成。 | |||
T12233 |
NK-1 Antagonist 1
Rolapitant intermediate |
Others | Others |
NK-1 Antagonist 1 is a NK-1 receptor antagonist. | |||
T31097 |
Crizotinib Interm 7654
Crizotinib Intermediate |
Others | Others |
Crizotinib Interm 7654 is an important intermediate for the synthesis of pharmaceutical compounds. | |||
T67020 |
Exatecan Intermediate 1
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Exatecan Intermediate 1 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67020,CAS号为 110351-94-5。 | |||
T28002 |
MDK71803
MDK-71803,Cefiderocol-intermediate, Cefiderocol-precursor,MDK 71803 |
Others | Others |
MDK71803 is an important intermediate or precursor for the synthesis of Cefiderocol, a potent siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. | |||
T67937 |
Ampreloxetine hydrochloride
TD-9855 HCl |
Others | Others |
Ampreloxetine hydrochloride (TD-9855 HCl) 具有抗炎活性,是治疗抑郁症和阿尔茨海默病的潜在化合物。 | |||
T38239 |
2'-Deoxy-2'-fluorouridine
|
Others | Others |
2'-Deoxy-2'-fluorouridine 是合成抗流感病毒试剂的中间体。 | |||
T19588 |
TP748
2-苄氧基恶唑 |
Others | Others |
TP748 是一种异恶唑,也是合成四环素的关键中间体。 | |||
T7838 |
Losartan Carboxaldehyde
|
COX | Immunology/Inflammation; Neuroscience |
Losartan Carboxaldehyde 是氯沙坦的中间醛代谢产物。它不能阻断 AT1-R ,但可以抑制内皮环氧合酶 (COX)-2 的表达,起到抗炎作用。 | |||
T9563 |
Type III-Intermediate7
|
Others | Others |
Type III-Intermediate7 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T9563。 | |||
T2569 |
Chlorotrianisene
tris(p-methoxyphenyl)chloroethylene,氯丁烯二烯,CTA,tri-p-anisylchloroethylene,氯烯雌醚,TACE |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; COX | Endocrinology/Hormones; Immunology/Inflammation; Neuroscience |
Chlorotrianisene (tri-p-anisylchloroethylene) 是长效、可口服、亲脂性高的合成三苯乙烯 (TPE) 衍生物和选择性雌激素受体调节剂,有雌激素活性,也有抗雌激素活性。它还有效抑制COX-1并抑制全血中的血小板聚集。 | |||
T1358 |
2,3-Dichloroanisole
|
Others | Others |
2,3-Dichloroanisole 是一种中间产物。 | |||
T14362L |
AY 9944 dihydrochloride
|
Others | Others |
AY 9944 dihydrochloride 是一个中间体。 | |||
T2290 |
8-Hydroxyquinoline-2-carboxaldehyde
|
Others | Others |
8-Hydroxyquinoline-2-carboxaldehyde 用作医药中间体。 | |||
T1697 |
debutylbupivacaine
|
Others | Others |
Debutylbupivacaine 是 ropivacaine hydrochloride 和 bupivacaine 的中间体。 | |||
T0540 |
Dibenzosuberol
|
Others | Others |
Dibenzosuberol 可用作医药中间体。 | |||
T5683 |
(2R,3S)-3-Phenylisoserine hydrochloride
|
Others | Others |
(2R,3S)-3-Phenylisoserine hydrochloride 是医药中间体。 | |||
T1702 |
Nortropinone hydrochloride
|
Others | Others |
Nortropinone hydrochloride 用作药物中间体。 | |||
T14954 |
Chlorthal-dimethyl
Dimethyl tetrachloroterephthalate |
Others | Others |
Chlorthal-dimethyl用作农药中间体。 | |||
T9934 |
5-Methoxyresorcinol
Flamenol,夫拉美诺 |
Others | Others |
5-Methoxyresorcinol (Flamenol) 是一个化学中间体。 | |||
T0549 |
4'-tert-Butylacetophenone
|
Others | Others |
4'-tert-Butylacetophenone 用作医药中间体。 | |||
T0667 |
Flecainide Impurity D
|
Others | Others |
Flecainide Impurity D 在工业中用作中间体。 | |||
T0553 |
4-Hydroxyisophthalic acid
|
Others | Others |
4-Hydroxyisophthalic acid 用作医药中间体。 | |||
T0527 |
2,3,4-Trimethoxybenzaldehyde
Benzaldehyde,三甲氧基苯甲醛,Trimethoxybenzaldehyde |
Others | Others |
2,3,4-Trimethoxybenzaldehyde (Trimethoxybenzaldehyde) 用作医药中间体。 | |||
T1727 |
4-Cyclohexyl-1-phenylthiosemicarbazide
|
Others | Others |
4-Cyclohexyl-1-phenylthiosemicarbazide 用作中间体 | |||
T0546 |
Trimethylacetic anhydride
Pivalic anhydride,三甲基乙酸酐 |
Others | Others |
Trimethylacetic anhydride (Pivalic anhydride) 用作医药中间体。 | |||
T22220 |
Methyl picolinate
2-吡啶甲酸甲酯,Methyl pyridine-2-carboxylate,2-Pyridinecarboxylic acid methyl ester,2-Carbomethoxypyridine |
Others | Others |
Methyl picolinate (Methyl picolinate) 用作医药中间体。 | |||
T0633 |
(2-Chlorophenyl)phenyl-methanone
|
Others | Others |
(2-Chlorophenyl)phenyl-methanone 用作医药中间体。 | |||
T0623 |
Diphenylacetonitrile
二苯乙腈,Dipan,Diphenatrile |
Others | Others |
Diphenylacetonitrile (Dipan) 用作除草剂和工业中间体。 | |||
T0658 |
2-(2-Hydroxyethyl)pyridine
|
Others | Others |
2-(2-Hydroxyethyl)pyridine 用作工业化学中间体。 | |||
T0630 |
Ethyleneurea
Imidazolidinone,2-咪唑烷酮 |
Others | Others |
Ethyleneurea (Imidazolidinone) 用作formaldehyde scavenger 和中间体。 | |||
T0552 |
Isonicotinamide
|
Others | Others |
Isonicotinamide 用作医药中间体,用于合成头孢氯铵等。 | |||
T4239 |
1,3-dimethyl-2-oxobenzimidazole-5-carbaldehyde
1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOLE-5-CARBALDEHYDE |
Others | Others |
1,3-dimethyl-2-oxobenzimidazole-5-carbaldehyde 是中间体。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3554 |
Cabazitaxel intermediate
|
Others | Others |
Cabazitaxel intermediate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3554,CAS号为 1354900-65-4。 | |||
TN7020 |
Astragenol
|
Others | Others |
Astragenol 是合成黄芪醇衍生物的中间体。它的衍生物具有抗炎作用,可用于前列腺癌的研究。 | |||
T9599 |
3,4,5-Trimethoxybenzaldehyde
|
Anti-infection; Antibacterial | Microbiology/Virology |
3,4,5-Trimethoxybenzaldehyde 是合成各种药物,特别是治疗细菌感染的甲氧苄啶的中间体,它有抗念珠菌功效并抑制粘附和生物膜。 | |||
T8178 |
Acetagastrodin
乙酰天麻素,Acegastrodine |
Others | Others |
Acetagastrodin (Acegastrodine) 是一种抗氧化剂,也是合成 DBPG 的中间体。 | |||
T5549 |
Melamine
Cyanurotriamide,Cyanuramide,三聚氰胺 |
Others | Others |
Melamine (Cyanurotriamide) 是合成三聚氰胺树脂和塑料材料的中间体,是环丙嗪的代谢产物。 | |||
T1341 |
Nortropine
Nortropenol,去甲托品醇 |
AChR | Neuroscience |
Nortropine (Nortropenol) 是托品碱分解和反应生成琥珀酸的中间体,可从Convolvulus subhirsutus 生物碱中分离得到。 | |||
T0043 |
Octodrine
二甲己胺,2-Amino-6-methylheptane,6-Methyl-2-heptylamine,1,5-Dimethylhexylamine |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Octodrine (2-Amino-6-methylheptane) 是一种中枢神经刺激剂,可增加痛阈、心率 (正变时效应) 和心肌收缩力 (正变力效应),可增加多巴胺和去甲肾上腺素 (noradrenaline) 的摄取。 | |||
T5595 |
Tropine
3alpha-Tropanol,托品醇,Pseudotropine |
Others | Others |
Tropine 是一种茄科植物的次生代谢产物,是抗胆碱能试剂。它是一种常见的用于合成各种生物活性生物碱(如 hyoscyamine、scopolamine)的中间体。 | |||
T4848 |
Mandelic acid
acidomandelico,DL-Mandelic acid,扁桃酸 |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
DL-Mandelic acid (acidomandelico) 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。 | |||
Fr14438 |
p-Toluic Acid
对甲基苯甲酸,4-Methylbenzoic acid |
Endogenous Metabolite | Metabolism |
p-Toluic Acid (4-Methylbenzoic acid) 是一种合成对氨基甲基苯甲酸 (PAMBA),是被取代的苯甲酸,是一种对甲苯腈等的中间体。 | |||
T5980 |
2-Ketoglutaric acid
α-酮戊二酸,alpha-酮戊二酸 |
Tyrosinase; Endogenous Metabolite | Metabolism; Proteases/Proteasome |
2-Ketoglutaric acid 是 Krebs 循环的中间体,可以产生 ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。 | |||
T5543 |
TriacetonaMine
四甲基哌啶酮,Odoratine,tempidon,tmpone,Vincubine,2,2,6,6-Tetramethyl-4-piperidinone |
Others | Others |
TriacetonaMine (Vincubine) 是一种合成医药产品、农药和聚合物光稳定剂的中间体。它是热解油的主要组分。它是植物和真菌提取物的人工制品,使用丙酮和氢氧化铵,或在分离过程的不同步骤中天然出现铵盐。 | |||
T8186 |
Xanthosine 5'-monophosphate sodium salt
XMP,黄苷-5′-单磷酸钠,L-XMP Sodium |
Others | Others |
Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) 是嘌呤代谢的一种中间体。它可用于研究遗传密码,核酸结构以及 DNA,RNA 和蛋白质合成。 | |||
T5588 |
cis,cis-Muconic acid
顺式-已二烯二酸,cis,cis-Muconate,cis,cis-2,4-Hexadienedioic acid |
Others | Others |
cis,cis-Muconic acid (cis,cis-2,4-Hexadienedioic acid) 是肺炎克雷伯菌的代谢中间体,是合成聚合物的重要单体,可以转化为己二酸和对苯二甲酸。它也是一种生物化学材料,可用于生产各种塑料和聚合物。它作为己二酸前体可用于合成 nylon-6,6。 | |||
T4721 |
β-Nicotinamide mononucleotide
NMN,β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸 |
Others; Endogenous Metabolite | Metabolism; Others |
β-nicotinamide mononucleotide 是烟酰胺磷酸核糖转移酶 (NAMPT) 反应的产物。β-nicotinamide mononucleotide的作用包括其在细胞生化功能、心脏保护、糖尿病、肥胖相关并发症和阿尔茨海默病中的作用。 | |||
T4970 |
LANOSTEROL
羊毛甾醇,3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol |
Endogenous Metabolite | Metabolism |
Lanosterol (3β-Hydroxy-8,24-lanostadiene) 是胆固醇合成的中间产物,能够诱导胆固醇合成的速率控制酶 HMG-CoA 还原酶的泛素化和降解。Lanosterol 可以抑制神经退行性疾病相关错误折叠蛋白的聚集和细胞毒性。 | |||
T4920 |
2-Ketoglutaric acid Sodium
Oxoglutaric acid,AKG,2-oxoglutarate monobasic,LPHA-酮戊二酸钠,α-Ketoglutaric acid sodium salt |
Tyrosinase; Endogenous Metabolite | Metabolism; Proteases/Proteasome |
2-Ketoglutaric acid Sodium (AKG) 是一种三羧酸循环的中间产物,它可以由谷氨酸通过谷氨酸脱氢酶氧化脱氨产生,也可以作为磷酸吡哆醛依赖的转氨化反应的产物(由支链氨基酸转氨酶介导),其中谷氨酸是常见的氨基供体。 | |||
T19127 |
3-Phosphoglyceric acid
|
Others | Others |
3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. It is involved in alveolar macrophage epigenetic regulation. | |||
TWO2724 |
N,N-Bis(2-hydroxyethyl)-p-phenylenediami
|
Others | Others |
N,N-Bis(2-hydroxyethyl)-p-phenylenediami 是中间体。 | |||
T8085 |
(-)-Corey lactone diol
科立内脂二醇,Corey Lactone Diol |
Others | Others |
(-)-Corey lactone diol 是 corey aldehyde 的还原形式,也是化学合成中的砌块。 | |||
T5078 |
Orotic acid monohydrate
2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate,乳清酸一水合物 |
Others; Endogenous Metabolite | Metabolism; Others |
Orotic acid monohydrate (2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate) 是内源性代谢产物的一种。 | |||
T0631 |
2-Phenylbutanoic acid
2-苯基丁酸,2-Phenylbutyric acid |
Others; Endogenous Metabolite | Metabolism; Others |
2-Phenylbutanoic acid (2-Phenylbutyric acid) 是内源性代谢产物的一种。 | |||
T4834 |
Indole-3-acetamide
3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺 |
Others; Endogenous Metabolite | Metabolism; Others |
Indole-3-acetamide 是一种 indole-3-acetic acid 的生物合成中间体。其中 Indole-3-acetic acid 是植物生长素类中最常见的天然植物生长激素。 | |||
T7965 |
5'-Deoxy-5-fluorocytidine
|
Others | Others |
5'-Deoxy-5-fluorocytidine 是 DNA 合成抑制剂 capecitabine 的中间代谢物。 | |||
T0568 |
3,4-Dimethoxyphenylacetic acid
Homoveratrumic acid,homoveratric acid,高藜芦酸 |
Others; Endogenous Metabolite | Metabolism; Others |
3,4-Dimethoxyphenylacetic acid (Homoveratrumic acid) 是一种化学合成中的砌块。 | |||
T2197 |
10-Deacetylbaccatin III
10-脱乙酰巴卡丁 III,10-脱乙酰基巴卡丁III |
Others | Others |
10-Deacetylbaccatin-III 是一种紫杉醇类似物制剂的中间体,具有抗癌活性。 | |||
T19711 |
Desmosterol
Desmesterol,24-Dehydrocholesterol |
Endogenous Metabolite | Metabolism |
Desmosterol(24-Dehydrocholesterol) 是一种胆固醇生物合成中间体,抑制巨噬细胞炎症小体活化,防止血管炎症和动脉粥样硬化。 | |||
T20911 |
Dibutyl maleate
AI3-00644,Butyl maleate,DBM (VAN),马来酸二丁酯 |
Others | Others |
Dibutyl maleate (DBM (VAN)) 是马来酸的二酯,可用作合成抗菌化合物的中间体。 | |||
T5804 |
Pneumocandin B0
纽莫康定B0,L-688786 |
Antibiotic; Antifungal | Microbiology/Virology |
Pneumocandin B0 (L-688786)是 Cancidas 的合成中间体。 | |||
TN1243 |
3-Aminocoumarin
3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine |
Others | Others |
3-Aminocoumarin (3-aminochromen-2-one) 是金属配合物的关键中间体。 | |||
Fr13711 |
Tropinone
|
Others | Others |
Tropinone 是一种可用作合成 Atropine 中间体的生物碱。 | |||
T4886 |
Dihydrouracil
二氢尿嘧啶,5,6-Dihydrouracil |
Endogenous Metabolite | Metabolism |
Dihydrouracil (5,6-Dihydrouracil) 是一种尿嘧啶的代谢产物,能够作为鉴定二氢嘧啶脱氢酶 (DPD) 缺陷的标志物。 | |||
T8091 |
trans-4-Hydroxycyclohexanecarboxylic Acid
|
Others | Others |
trans-4-Hydroxycyclohexanecarboxylic acid 是一种合成环己烷酸的底物 (substrate)。它是肠道细菌代谢的副产物 (by-product),能够通过尿路排泄。 | |||
T15254 |
Ethyl acetoacetate
Ethyl acetylacetate |
Others; Antibacterial | Microbiology/Virology; Others |
Ethyl acetoacetate (Ethyl acetylacetate) 是一种细菌生物膜抑制剂。Ethyl acetoacetate 是一种酯类,是一种可用于多种化合物合成的中间体。 | |||
T2748 |
Cortodoxone
可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol |
Glucocorticoid Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Cortodoxone (11-Desoxycortisol) 是糖皮质类固醇激素,能够氧化为皮质醇。 | |||
T0136 |
Citicoline
CDP-Choline,Citicholine,尼古林,cytidine 5'-diphosphocholine,cytidine diphosphate-choline |
Apoptosis; Dopamine Receptor; Endogenous Metabolite | Apoptosis; GPCR/G Protein; Metabolism; Neuroscience |
Citicoline (CDP-Choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体,有神经保护作用。 | |||
T8949 |
UDP-g acid
|
Others | Others |
UDP-g acid 是一种用于生产多糖的糖,是抗坏血酸生物合成的中间体。 | |||
T7936 |
Benzopinacole
|
Others | Others |
Benzopinacole 是一种抗阿米巴药物,可作为中间体合成多种化合物。 | |||
T1662 |
5-Aminolevulinic acid hydrochloride
氨基酮戊酸,Hydrangin,5-ALA,5-Aminolevulinic acid HCl,5-氨基乙酰丙酸盐酸盐,ALA hydrochloride |
Apoptosis; Mitophagy; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Metabolism |
5-Aminolevulinic acid hydrochloride (5-ALA) 是体内血红素生物合成的中间体,也是四吡咯的通用前体。 | |||
T8095 |
O-Acetylserine
O-乙酰-L-丝氨酸,O-Acetyl-L-serine,O-乙醯絲胺酸 |
Others; Endogenous Metabolite | Metabolism; Others |
O-Acetylserine (O-Acetyl-L-serine) 是细菌和植物中半胱氨酸合成过程中的中间体。 | |||
T0532 |
5,6-Dihydro-5-methyluracil
5, 6-Dihydrothymine,二氢朐腺嘧啶,Dihydrothymine |
Nucleoside Antimetabolite/Analog; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Dihydrothymine 是胸腺嘧啶的中间代谢产物之一,来源于动植物,浓度过高时会产生毒性。 | |||
T20255 |
L-Galactose
Galactose, L- |
Endogenous Metabolite | Metabolism |
L-Galactose (Galactose, L-) 是一种天然产物,广泛存在动植物体内。L-Galactose 在Pistia stratiotes 中被证明是D-葡萄糖转化为草酸的分子途径中的关键中间体。 | |||
TMS2262 |
(-)-CAMPHOR
L-Camphor,左旋樟脑 |
Others | Others |
(-)-CAMPHOR (L-Camphor) 是樟脑的手性中间体,在食品中用作风味添加剂和甜味剂。 | |||
T4942 |
Galactose 1-phosphate Potassium salt
D-半乳糖 1-磷酸二钾盐五水合物,α-D-Galactose-1-phosphate Dipotassium Pentahydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Galactose 1-phosphate Potassium salt (α-D-Galactose-1-phosphate Dipotassium Pentahydrate) 是一种半乳糖代谢中的中间体和核苷酸糖。 | |||
T67447 |
2-Methylanisole
|
Others | Others |
2-Methylanisole 是一种单甲氧基苯,是一种食品添加剂,可作为合成有甲基对苯二酚为核心的化合物的中间体 。 | |||
T5568 |
H-Tyr(3-I)-OH
3-碘-L-酪氨酸,3-Iodo-L-tyrosine |
Endogenous Metabolite | Metabolism |
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) 是酪氨酸羟化酶抑制剂和甲状腺激素 的中间体。 | |||
T9780 |
3,4, 5-trimethoxyphenylacetic acid
|
Endogenous Metabolite | Metabolism |
3,4, 5-trimethoxyphenylacetic acid 是有机合成中常见的中间体,其主要用途是将其羧基转化为相应的用途。 | |||
T2905 |
5α-Cholestan-3-one
5-Α-胆甾烷-3-酮,Coprostanone,5alpha-Cholestan-3-one |
Others; Endogenous Metabolite | Metabolism; Others |
5α-Cholestan-3-one (Coprostanone) 是内源性代谢产物的一种。 | |||
T66911 |
1,3-Dimethoxybenzene
Resorcinol dimethyl ether |
Others | Others |
1,3-Dimethoxybenzene (Resorcinol dimethyl ether) 是一种来自德国榛子中的二甲氧基苯类化合物,是合成其他化合物的中间体。 | |||
T0584L |
Maltose monohydrate
麦芽糖-水合物,麦芽糖一水合物,D-(+)-Maltose monohydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Maltose monohydrate (D-(+)-Maltose monohydrate) 是细菌的能量来源。它是来自淀粉和麦芽的右旋二糖,在酿造中用作能够发酵中间体和甜味剂。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03418 |
Rotavirus A (strain St. Thomas 3) VP6 Protein (His)
Intermediate capsid protein VP6 |
RV-A | P. pastoris (Yeast) |
Rotavirus A (strain St. Thomas 3) VP6 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is B1NKU0. | |||
TMPH-03417 |
Rotavirus A (strain Nebraska calf diarrhea virus) VP6 Protein (His)
Intermediate capsid protein VP6 |
RV-A | E. coli |
Rotavirus A (strain Nebraska calf diarrhea virus) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.8 kDa and the accession number is A7J3A1. | |||
TMPH-01051 |
CILP Protein, Human, Recombinant (His & Myc)
CILP-1,Cartilage intermediate-layer protein,CILP,Ca... |
Human | Baculovirus Insect Cells |
CILP Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 55.7 kDa and the accession number is O75339. | |||
TMPH-03419 |
Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His)
Intermediate capsid protein VP6 |
RV-A | E. coli |
Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P03530. | |||
TMPH-03420 |
Rotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) VP6 Protein (His)
Intermediate capsid protein VP6 |
RV-A | E. coli |
Rotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.8 kDa and the accession number is P04509. | |||
TMPH-01052 |
CILP2 Protein, Human, Recombinant (GST & His & Myc)
Cartilage intermediate layer protein 2,CILP-2,CILP2 |
Human | E. coli |
May play a role in cartilage scaffolding. CILP2 Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession number is Q8IUL8. | |||
TMPH-01196 |
DYNC1I1 Protein, Human, Recombinant (His)
DH IC-1,DNCIC1,Cytoplasmic dynein 1 intermediate ch... |
Human | Baculovirus Insect Cells |
DYNC1I1 Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPH-02151 |
OXCT1 Protein, Human, Recombinant (His)
OXCT1,Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mito... |
Human | E. coli |
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. OXCT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.1 kDa and the accession number is P55809. | |||
TMPY-04329 |
Vimentin Protein, Human, Recombinant (His)
CTRCT30,HEL113,vimentin |
Human | Baculovirus Insect Cells |
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ... | |||
TMPH-01340 |
Filaggrin Protein, Human, Recombinant (His)
Filaggrin,FLG |
Human | P. pastoris (Yeast) |
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. Filaggrin Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.8 kDa and the accession number is P20930. | |||
TMPH-00174 |
MURG Protein, Bacillus subtilis, Recombinant (His)
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyro... |
Bacillus subtilis | E. coli |
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). MURG Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 43.9 kDa and the accession number is P37585. | |||
TMPH-01758 |
NEFL Protein, Human, Recombinant
68 kDa neurofilament protein,NEFL,Neurofilament triplet L pr... |
Human | E. coli |
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFL Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 61.5 kDa and the accession number is P07196. | |||
TMPH-01759 |
NEFL Protein, Human, Recombinant (His & SUMO)
Neurofilament triplet L protein,Neurofilament light polypept... |
Human | E. coli |
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFL Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with C-6xHis-SUMO tag. The predicted molecular weight is 52.4 kDa and the accession number is P07196. | |||
TMPH-02805 |
NEFL Protein, Mouse, Recombinant (His)
68 kDa neurofilament protein,Neurofilament triplet L protein... |
Mouse | P. pastoris (Yeast) |
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFL Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.4 kDa and the accession number is P08551. | |||
TMPH-01216 |
DSG1 Protein, Human, Recombinant (His & Myc)
Cadherin family member 4,DGI,Pemphigus foliaceus antigen,CDH... |
Human | E. coli |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | |||
TMPH-01760 |
NEFM Protein, Human, Recombinant (His & Myc)
Neurofilament 3,Neurofilament triplet M protein,160 kDa neur... |
Human | E. coli |
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFM Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.8 kDa and the accession number is P07197. | |||
TMPH-01256 |
Dystonin Protein, Human, Recombinant (His & SUMO)
DT,DST,BPAG1,BP240,BP230,KIAA0728,Dystonin,DMH |
Human | E. coli |
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... | |||
TMPH-01257 |
Dystonin Protein, Human, Recombinant (His)
DT,BP230,Dystonin,BP240,DST,DMH,BPAG1,KIAA0728 |
Human | P. pastoris (Yeast) |
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... | |||
TMPJ-00846 |
GFAP Protein, Human, Recombinant (His)
Glial Fibrillary Acidic Protein,GFAP |
Human | E. coli |
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desm... | |||
TMPH-01217 |
DSG3 Protein, Human, Recombinant (E. coli, His)
130 kDa pemphigus vulgaris antigen (PVA),CDHF6,DSG3,Cadherin... |
Human | E. coli |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | |||
TMPH-02674 |
GFAP Protein, Mouse, Recombinant
Gfap,Glial fibrillary acidic protein |
Mouse | Baculovirus Insect Cells |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPH-02673 |
GFAP Protein, Mouse, Recombinant (His & SUMO)
Glial fibrillary acidic protein,Gfap |
Mouse | E. coli |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPH-03340 |
NEFH Protein, Rat, Recombinant (His & Myc)
Nefh,Neurofilament triplet H protein,Neurofilament heavy pol... |
Rat | E. coli |
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NEF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFH Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The pre... | |||
TMPH-00736 |
LpxK Protein, E. coli, Recombinant (His & Myc)
Tetraacyldisaccharide 4'-kinase,Lipid A 4'-kinase,lpxK |
E. coli | E. coli |
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | |||
TMPH-01757 |
NEFH Protein, Human, Recombinant (His & Myc & SUMO)
200 kDa neurofilament protein,NEFH,Neurofilament heavy polyp... |
Human | E. coli |
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFH Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc... | |||
TMPH-02244 |
Trichohyalin Protein, Human, Recombinant (His & Myc)
TCHH,Trichohyalin |
Human | E. coli |
Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing dur... | |||
TMPJ-00882 |
Desmin Protein, Human, Recombinant (His)
DES,Desmin |
Human | E. coli |
Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibr... | |||
TMPH-01219 |
DSP Protein, Human, Recombinant (His)
DSP,Desmoplakin,DP,250/210 kDa paraneoplastic pemphigus anti... |
Human | P. pastoris (Yeast) |
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. | |||
TMPH-01675 |
Meteorin Protein, Human, Recombinant (His)
Meteorin,METRN |
Human | E. coli |
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. | |||
TMPH-02624 |
Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO)
Desmoglein-1,DGI,Dsg1a,Dsg1,Desmosomal glycoprotein I,Dsg1-a... |
Mouse | E. coli |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 77.2 kDa and the accession number is Q61495. | |||
TMPH-03083 |
CrtX Protein, Pantoea ananas, Recombinant (His & Myc)
Zeaxanthin glucosyltransferase,ugt101,crtX |
Pantoea ananas | Baculovirus Insect Cells |
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 51.1 kDa and the accession number is P21686. | |||
TMPH-03402 |
STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc)
STR1,Strictosidine synthase |
Rauvolfia serpentina | E. coli |
Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is P68175. | |||
TMPJ-00495 |
ISG15 Protein, Human, Recombinant (His)
ISG15,Ubiquitin Cross-Reactive Protein,G1P2,Interferon-Induc... |
Human | E. coli |
Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermed... | |||
TMPH-03084 |
CrtX Protein, Pantoea ananas, Recombinant (E. coli, His & Myc)
Zeaxanthin glucosyltransferase,crtX,ugt101 |
Pantoea ananas | E. coli |
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.7 kDa and the accession number is P21686. | |||
TMPH-01218 |
DSP Protein, Human, Recombinant (His & SUMO)
Desmoplakin,DSP,DP,250/210 kDa paraneoplastic pemphigus anti... |
Human | E. coli |
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. DSP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.1 kDa and the accession number is P15924. | |||
TMPH-00858 |
NT5C Protein, Human, Recombinant (His & Myc)
5'(3')-deoxyribonucleotidase, cytosolic type,NT5C,Cytosolic ... |
Human | E. coli |
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. NT5C Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.4 kDa and the accession number is Q8TCD5. | |||
TMPJ-00982 |
DHS Protein, Human, Recombinant (His)
DS,Deoxyhypusine Synthase,DHPS,DHS |
Human | E. coli |
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | |||
TMPH-02572 |
TMEM2 Protein, Mouse, Recombinant (His)
Transmembrane protein 2,Cell migration-inducing hyaluronidas... |
Mouse | E. coli |
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. | |||
TMPH-01678 |
MMUT Protein, Human, Recombinant (His)
MMUT,Methylmalonyl-CoA mutase, mitochondrial,Methylmalonyl-C... |
Human | E. coli |
Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle. MMUT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 84.8 kDa and the accession number is P22033. | |||
TMPH-03452 |
NDPK Protein, S. cerevisiae, Recombinant (His)
Nucleoside diphosphate kinase,YNK1 |
Saccharomyces cerevisiae | P. pastoris (Yeast) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is P36010. | |||
TMPJ-01426 |
SARS-CoV-2 NSP2 Protein (His)
SARS-CoV 2 nsp2,SARS-CoV 2 p65 homolog |
SARS-CoV-2 | E. coli |
The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins incorporate 16 protein domains (nsps). The putative non-structural protein 2 (nsp2) of SARS-CoV plays an important role in viral transcription and replication, and is an attractive target for anti-SARS drug development. | |||
TMPH-02971 |
Vimentin Protein, Mouse, Recombinant (His & Myc)
Vim,Vimentin |
Mouse | HEK293 Cells |
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.; Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. Vimentin Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.6 kDa and the accession number i... | |||
TMPK-00861 |
A2AR Protein-VLP, Human, Recombinant
RDC8,Adenosine A2a R,ADORA2,ADORA 2,ADORA2A,A2aR |
Human | HEK293 Cells |
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult. | |||
TMPJ-01298 |
PRADC1 Protein, Human, Recombinant (His)
Protease-associated domain-containing protein of 21 kDa,Prot... |
Human | HEK293 Cells |
PRADC1, also known as C2orf7 or PAP21, is short for Protease-associated domain-containing protein 1. It is a 188 aa. with a 21 aa. signal, and the 171 located Asn can be glycosylated. PRADC1 has two mutagenesis which are N121Q and N171Q. This protein is secreted and highly expressed in skeletal muscle, heart and liver. It is expressed at intermediate level in kidney. | |||
TMPH-00099 |
NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Nucleoside diphosphate kinase 1,NDK1,Nucleoside diphosphate ... |
Arabidopsis thaliana | P. pastoris (Yeast) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a role in response to reactive oxygen species (ROS) stress. NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P39207. | |||
TMPH-00917 |
ADH4 Protein, Human, Recombinant (GST)
Alcohol dehydrogenase 4,Alcohol dehydrogenase 2,All-trans-re... |
Human | E. coli |
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones. ADH4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 67.2 kDa and the accession n... | |||
TMPH-03451 |
NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)
YNK1,Nucleoside diphosphate kinase |
Saccharomyces cerevisiae | E. coli |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P36010. | |||
TMPH-03195 |
Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc)
Protein archease |
Pyrococcus horikoshii | E. coli |
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.1 kDa and the accession number is O59205... | |||
TMPH-02970 |
Vimentin Protein, Mouse, Recombinant (E. coli, His & Myc)
Vimentin,Vim |
Mouse | E. coli |
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.; Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. Vimentin Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.0 kDa and the access... | |||
TMPH-01241 |
TOP1 Protein, Human, Recombinant (His & Myc)
DNA topoisomerase 1,TOP1,DNA topoisomerase I |
Human | Baculovirus Insect Cells |
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates a... | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIH-0505 |
Rosuvastatin-d3 intermediate
|
||
Rosuvastatin-d3 intermediate 是 Rosuvastatin intermediate 的氘代化合物。 | |||
TMIH-0066 |
Acalabrutinib intermediate-d4
|
||
Acalabrutinib intermediate-d4 是 Acalabrutinib intermediate 的氘代化合物。Acalabrutinib intermediate 的 CAS 号为 1420478-90-5。 | |||
TMID-0111 |
11-Deoxycortisol-2,2,4,6,6-d5
|
||
11-Deoxycortisol-2,2,4,6,6-d5 是 11-Deoxycortisol 的氘代化合物。11-Deoxycortisol 的 CAS 号为 152-58-9。Cortodoxone是糖皮质类固醇激素,能够氧化为皮质醇。 | |||
TMID-0029 |
Succinic-2,2,3,3-d4 Acid
|
||
Succinic-2,2,3,3-d4 Acid 是 Succinic Acid 的氘代化合物。Succinic Acid 的 CAS 号为 110-15-6。Succinic acid 是无氧代谢的发酵产物,也是三羧酸循环的中间产物。 | |||
TMIJ-0518 |
L-Kynurenine-d4-1
|
||
L-Kynurenine-d4-1 是 L-Kynurenine 的氘代化合物。L-Kynurenine 的 CAS 号为 2922-83-0。L-Kynurenine是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。 | |||
TMID-0071 |
L-Kynurenine-d4
|
||
L-Kynurenine-d4 是 L-Kynurenine 的氘代化合物。L-Kynurenine 的 CAS 号为 2922-83-0。L-Kynurenine是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。 | |||
TMID-0056 |
(±)-Mandelic-2,3,4,5,6-d5 Acid
|
||
(±)-Mandelic-2,3,4,5,6-d5 Acid 是 (±)-Mandelic Acid 的氘代化合物。(±)-Mandelic Acid 的 CAS 号为 90-64-2。DL-Mandelic acid 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。 | |||
TMID-0167 |
6-Hydroxypurine-d4
|
||
6-Hydroxypurine-d4 是 6-Hydroxypurine 的氘代化合物。6-Hydroxypurine 的 CAS 号为 68-94-0。Hypoxanthine,也被称为 purine-6-ol 或 Hyp,属于嘌呤类有机化合物。Hypoxanthine 是一种天然存在的嘌呤衍生物,是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下,Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤,黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。 | |||
T70313 |
Indoxyl Sulfate-d5 potassium salt
|
||
Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). ... |