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Search Results for " protoporphyrin ix "

Targets Recommended: Autophagy

14

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T36113	Cobaltic Protoporphyrin IX chloride Protoporphyrin IX cobaltic chloride	Autophagy	Autophagy
	Cobaltic Protoporphyrin IX chloride (CoPP)是一种有效的血红素加氧酶 1(HO-1)诱导剂，具有抗病毒活性，通过诱导 I 型 IFN 反应来抑制甲型流感病毒(IAV)感染。
T13161	Tin-protoporphyrin IX dichloride SnPPIX,SnPPIX dichloride	Virus Protease; Autophagy	Autophagy; Microbiology/Virology
	Tin-protoporphyrin IX dichloride (SnPPIX dichloride) 是血红素加氧酶-1 (HO-1) 抑制剂，具有抗病毒活性，抑制登革热和黄热病病毒，可改善肝部分切除术后的肝脏再生。
T39603	Mn(II) protoporphyrin IX	Others	Others
	Mn(II) protoporphyrin IX is a potent intravenous paramagnetic magnetic resonance contrast agent, known for its strong paramagnetic properties.
T39700	Ga(III) protoporphyrin IX	Others	Others
	Ga(III)protoporphyrin-IX, a model for interporphyrin interactions in malaria pigment, possesses potent antibacterial effects against gram-negative, gram-positive, and acid-fast bacteria. It exhibits high solubility in methanol (MeOH) and serves as a malarial pigment analogue for drug development, as well as a potential antibacterial agent.
T39026	Ni(II) protoporphyrin IX	Others	Others
	Ni(II) protoporphyrin IX is a metalloporphyrin compound characterized by its limited propensity for axial ligation and its distortion upon binding to ferrochelatase.
T38980	Mg(II) protoporphyrin IX	Others	Others
	Mg(II) protoporphyrin IX is a crucial compound in the synthesis of chlorophyll in Chlorella. It also serves as a negative regulator of nuclear photosynthetic gene expression. Additionally, Mg(II) protoporphyrin IX is employed as a valuable research tool for investigating the signaling molecule involved in plastid-to-nucleus communication.
T38935	Cu(II) protoporphyrin IX	Others	Others
	Cu (II) Protoporphyrin IX functions as a negative control for Zn (II) Protoporphyrin, a heme oxygenase inhibitor. Heme oxygenase is involved in tumor cell resistance to chemotherapy and the regulation of free radical formation, inflammation, and vascular repair.
T83663	Mn(III) Protoporphyrin IX Chloride Manganese(III) Protoporphyrin IX Chloride	Others	Others
	Mn(III) protoporphyrin IX chloride是一种金属卟啉，当浓度为10 µM时，能在鸡胚肝细胞中诱导δ-氨基酮戊二酸合成酶和血红素加氧酶(HO)基因的mRNA表达，这些酶分别催化血红素生物合成和降解的限速步骤。Mn(III) protoporphyrin IX chloride含纳米仿生物已被用于体外纤维蛋白凝块的磁共振成像(MRI)研究。此外，它还被用于Mn(III) protoporphyrin IX-6(7)-甘氨酰-甘氨酰-L-组氨酸甲酯(MnGGH)的合成，MnGGH是一种具有微过氧化物酶活性的金属卟啉衍生物。
T13396	Zinc Protoporphyrin Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX	Apoptosis; Reactive Oxygen Species; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) 是一种具有口服活性的，竞争性血红素加氧酶-1 抑制剂，显著减弱间苯三酚对 H2O2 的保护作用，具有抗癌活性。它用于评估人群铁状态与血红蛋白浓度的组合，也可用作个体孕妇和儿童缺铁的筛查标志物。
T78623	Cobalt protoporphyrin IX	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Cobalt protoporphyrin IX 作为一种特异性的血红素加氧酶-1 (HO-1) 诱导剂，表现出对甲型流感病毒 (IAV) 的广谱抗病毒活性。
T19147	5-ALA benzyl ester hydrochloride Benzyl-ALA hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) 是一种原卟啉前体，可用作光检测器。5-ALA benzyl ester hydrochloride 在结肠癌细胞系中可以诱导原卟啉 IX (PPIX) 的积聚。
T40588	Acifluorfen	Others	Others
	Acifluorfen 是一种除草剂。Acifluorfen 是一种原卟啉原氧化酶抑制剂，可促进原卟啉 IX 的积累，并诱导啮齿动物肝脏发生肿瘤。它会引起敏感植物物种中的色素和脂质强烈的光氧化破坏。
T19421	Methyl aminolevulinate	Others	Others
	Methyl aminolevulinate is a prodrug that can be metabolized to Protoporphyrin IX. Methyl aminolevulinate is an agent used as a sensitizer in photodynamic therapy (PDT).
T84999	CP94 CGP 46700	Others	Others
	CP94, an iron chelator, enhances protoporphyrin IX photobleaching and reduces the viability of A431 squamous epithelial carcinoma cells at a 150 µM concentration with photodynamic therapy (PDT) using protoporphyrin IX precursors such as aminolevulinic acid (ALA), methyl aminolevulinate (MAL), or hexylaminolevulinate (HAL). Additionally, CP94 (2 mg/ml in drinking water) lowers hepatic non-heme and ferritin-bound iron levels while increasing hepatic protoporphyrin levels in mice. It also counterac...

化合物

Cobaltic Protoporphyrin IX chloride

Cat.No: T36113

Synonym: Protoporphyrin IX cobaltic chloride

Target: Autophagy

Tin-protoporphyrin IX dichloride

Cat.No: T13161

Synonym: SnPPIX,SnPPIX dichloride

Target: Virus Protease, Autophagy

Mn(II) protoporphyrin IX

Cat.No: T39603

Target: Others

Ga(III) protoporphyrin IX

Cat.No: T39700

Target: Others

Ni(II) protoporphyrin IX

Cat.No: T39026

Target: Others

Mg(II) protoporphyrin IX

Cat.No: T38980

Target: Others

Cu(II) protoporphyrin IX

Cat.No: T38935

Target: Others

Mn(III) Protoporphyrin IX Chloride

Cat.No: T83663

Synonym: Manganese(III) Protoporphyrin IX Chloride

Target: Others

Zinc Protoporphyrin

Cat.No: T13396

Synonym: Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX

Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite

Cobalt protoporphyrin IX

Cat.No: T78623

Target: Reactive Oxygen Species

5-ALA benzyl ester hydrochloride

Cat.No: T19147

Synonym: Benzyl-ALA hydrochloride

Target: Others, Endogenous Metabolite

Cat.No: T40588

Target: Others

Methyl aminolevulinate

Cat.No: T19421

Target: Others

Cat.No: T84999

Synonym: CGP 46700

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T1192	Protoporphyrin IX PPIX,原卟啉,原卟啉IX	Others; Endogenous Metabolite	Metabolism; Others
	Protoporphyrin IX (PPIX) 是一种四吡咯，是血红素、细胞色素 c 和叶绿素的代谢前体。

天然产物

Protoporphyrin IX

Cat.No: T1192

Synonym: PPIX,原卟啉,原卟啉IX

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00265	Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) Ferrochelatase, mitochondrial,Protoheme ferro-lyase,FECH,Hem...	Bovine	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Mycd tag. The predicted molecular weight is 58.1 kDa and the accession number is P22600.
TMPH-01332	Ferrochelatase Protein, Human, Recombinant (His & Myc) Ferrochelatase, mitochondrial,Heme synthase,Protoheme ferro-...	Human	E. coli
	Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P22830.
TMPH-03128	TSPO Protein, Pig, Recombinant (His & Myc & SUMO) TSPO,Peripheral-type benzodiazepine receptor,Translocator pr...	Sus scrofa (Pig)	E. coli
	Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. TSPO Protein, Pig, Recombinant (His & Myc & SUMO) is expressed in E. coli e...

重组蛋白

Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00265

Species: Bovine

Expression System: E. coli

Ferrochelatase Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01332

Species: Human

Expression System: E. coli

TSPO Protein, Pig, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03128

Species: Sus scrofa (Pig)

Expression System: E. coli

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