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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4468 |
WAY 316606
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
WAY 316606 是一种分泌性糖蛋白Wnt 的拮抗剂,是一种分泌蛋白sFRP-1抑制剂,在 FP 结合检测使用中,它作用于 sFRP-1 的IC50为 0.5 μM。 | |||
T23529 |
WAY 316606 HCl (915759-45-4 free base)
WAY 316606 HCl |
Others | Others |
WAY 316606 HCl is a selective small-molecule inhibitor of secreted frizzled-related protein-1 (EC50: 0.65 μM). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00918 |
SFRP1 Protein, Human, Recombinant (His)
SARP2,secreted frizzled-related protein 1,FRP-1,FRP1,FRP, |
Human | HEK293 Cells |
Secreted frizzled-related protein 1, also known as sFRP1, is a 35 kDa prototypical member of the SFRP family. SFRP family consists of five secreted glycoproteins in humans acting as extracellular signaling ligands. Each is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs act as soluble modulators of Wnt s... | |||
TMPY-01106 |
FSTL1 Protein, Human, Recombinant (His)
MIR198,FSL1,follistatin-like 1,FRP |
Human | HEK293 Cells |
FSTL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is Q12841-1. | |||
TMPJ-00191 |
FSTL1 Protein, Human, Recombinant
FRP,Follistatin-Related Protein 1,Follistatin-Like Protein 1... |
Human | E. coli |
Follistatin-Related Protein 1 (FSTL1) is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain, and one VWFC domain. Its functional significance in physiological and pathological processes is not completely understood. However, FSTL1 is thought to modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 maybe an autoantigen associated with rheumatoid arthritis. |