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Search Results for " fsh "

33

抑制剂 & 化合物

1

天然产物

15

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T76566 Fsh receptor-binding inhibitor fragment(bi-10)

FSHreceptor-binding inhibitor fragment(bi-10) 是一种有效的 FSH 拮抗剂。FSHreceptor-binding inhibitor fragment(bi-10) 阻断 FSHFSHR 的结合,并在受体水平上改变 FSH 的作用。FSHreceptor-binding inhibitor fragment(bi-10) 导致小鼠排卵抑制和卵泡闭锁。FSHreceptor-binding inhibitor fragment(bi-10) 通过下调卵巢中 FSHR 和 ERβ的过度表达来抑制卵巢癌发生。
T1908 MHY1485

mTOR; Autophagy Autophagy; PI3K/Akt/mTOR signaling
MHY1485 是一种 mTOR 激活剂。它通过抑制自噬体和溶酶体之间的融合来抑制自噬过程,导致 LC3II 蛋白的积累和自噬体增大。
T3630 Relugolix

RVT-601,瑞卢戈利,TAK-385

GNRH Receptor GPCR/G Protein
Relugolix (RVT-601) 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比,它对人和猴子的受体具有高亲和力和强拮抗活性,它们的 IC50值分别为0.33 nM 和0.32 nM。它可用于研究性激素依赖性疾病,如子宫肌瘤、子宫内膜异位症、前列腺癌等。
T76222 hFSH-β-(33-53) (TFA)

hFSH-β-(33-53) TFA 是一种含有硫醇的肽,对应于第二个 FSH 受体结合域,是 FSHR(卵泡刺激素受体) 拮抗剂。hFSH-β-(33-53) TFA 抑制 FSH 与受体的结合,是 Sertoli 细胞中雌二醇合成的部分激动剂。
T72835 FSHR agonist 1

Others Others
FSHR agonist 1是一种对卵泡刺激素(FSH)受体(FSHR)具有高亲和力并能引起变构的激动剂,具有pEC50值为7.72。它通过与TMD广泛相互作用直接激活FSHR。
TP1342L GnRH-I acetate

GnRH-I acetate(33515-09-2 free base)

Others Others
GnRH-I acetate 在血液中释放具有生物活性的促卵泡激素 (FSH) 和促黄体激素 (LH)。
T9380L Antide acetate

安替肽,Antide acetate (112568-12-4 Free base)

LHRH Endocrinology/Hormones
Antide acetate 是一种 LHRH 拮抗剂,可抑制垂体释放 LH 和 FSH
T5520L Cetrorelix diacetate

NS-75A,醋酸西曲瑞克,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate

GNRH Receptor GPCR/G Protein
Cetrorelix diacetate (NS-75A) 是GnRH 受体的强效拮抗剂(IC50:1.21 nM)。
T21309 Nafarelin acetate(76932-56-4 free base)

RS-94991-298,醋酸萘法瑞林,Nafarelin acetate,Nafarelin acetate hydrate,Synarel

GNRH Receptor GPCR/G Protein
Nafarelin acetate(76932-56-4 free base) (RS-94991-298) 是一种 GnRH 激动剂,可作为 GnRH 的类似物。 Nafarelin acetate(76932-56-4 free base) 导致促性腺激素促黄体激素 (LH) 和促卵泡激素 (FSH) 的垂体分泌减少。它可用于治疗雌激素依赖性病症。
T21410 Triptorelin acetate(57773-63-4 free base)

醋酸曲普瑞林,Wy 42422,Triptorelin Acetate,CL 118532,AY 25650,CL 118,532,Wy 42462,BIM 21003

GNRH Receptor GPCR/G Protein
Triptorelin acetate(57773-63-4 free base) (CL 118,532) 用作 GnRH 激动剂。它通过引起垂体的持续刺激来减少垂体促性腺激素促黄体激素 (LH) 和促卵泡激素 (FSH) 的分泌。曲普瑞林可用于治疗激素反应性癌症,如乳腺癌或前列腺癌、性早熟、雌激素依赖性疾病和辅助生殖。
T2597 Norgestrel

甲基炔诺酮,SH-850,FH 122-A,炔诺孕酮,WY-3707,SH-70850

Estrogen/progestogen Receptor; Reactive Oxygen Species Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
Norgestrel (WY-3707) 是一种孕酮的合成类似物,是一种口服避孕药中常见的化合物,也是一种神经保护性强抗氧化剂,能够防止光诱导的感光细胞中的ROS 的生成以及细胞死亡。
T82307 Glp-His-Pro-Gly-NH2

pGlu-His-Pro-Gly-NH2

pGlu-His-Pro-Gly-NH2(Glp-His-Pro-Gly-NH2)为含四氨基酸肽类化合物,可激发促性腺激素、黄体生成素(LH)与促卵泡激素(FSH)释放。
T76620 (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH

(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH 是黄体生成素释放激素 (LHRH) 的类似物。LHRH 通过刺激垂体黄体生成素 (LH) 和促卵泡激素 (FSH) 的释放,在控制生殖中发挥核心作用。
T76615 (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH

(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH是一种LHRH(黄体生成素释放激素)的类似物,主要通过激活垂体分泌黄体生成素(LH)和促卵泡激素(FSH)来在生殖调控中发挥核心作用。
T83489 [Lys8] LH-RH

"[Lys8] LH-RH"为LH-RH的类似物, 能够有效促进LH与FSH的释放。
T25443 FW 34569

FW-34-569,FW34569,FW 34-569,FW-34569,FW34-569

Others Others
FW 34569 is an enkephalin analogue. It stimulated growth hormones and prolactin release and inhibited the release of cortisol and LH, while FSH remained unchanged.
T83498 [D-Phe2,D-Ala6]-LH-RH

Wy 18185

[D-Phe2,D-Ala6]-LH-RH 为有效LH-RH拮抗剂,展现了显著的抗LH/FSH-RH及抗排卵活性。
T78515 Follicle-stimulating hormone

Others Others
卵泡刺激素(Follicle-stimulating hormone, FSH)为一种由垂体前叶分泌的异二聚体糖蛋白,其参与调控动物的生殖能力与繁殖效率。
T21375 Clomifene

Omifin,D,Chloramiphene,Clomiphene,Clomiphene free base,Citrate

Others Others
Clomifene is a selective estrogen receptor modulator (SERM), it has both estrogenic and anti-estrogenic activities. This agent causes the release of the pituitary gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH), leading to ov
T63572 Org 43553

Others Others
Org 43553 是口服具有活力的低分子量 (LMW) 促黄体生成素受体(LH-R)激动剂,能够激动人 LH (EC50: 3.7 nM)和 FSH 受体(EC50: 110 nM) 。Org 43553 能够用于研究内分泌。
T76616 (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH

(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH 是一种黄体生成素释放激素 (LHRH) 的类似物,主要通过促进垂体分泌黄体生成素 (LH) 和促卵泡激素 (FSH) 来在生殖调控中发挥关键作用。
T82162 Human follicular gonadotropin releasing peptide

hF-GRP

Human follicular gonadotropin releasing peptide (hF-GRP)是一种刺激垂体分泌促黄体激素(LH)及促卵泡激素(FSH)的激素类多肽,其作用可在体外实现。
T81390 Prolactin-Releasing Peptide (1-31) (rat)

Prolactin-Releasing Peptide (1-31) (rat) 通过减少禁食诱导的大鼠食物摄入,有效提升血浆LH、FSH及睾酮水平。
T68525 Nafarelin acetate hydrate

Others Others
Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) which acts as an analog of GnRH. Nafarelin increases the release of FSH and LH by the anterior pituitary, which in turn leads to an increase of estrogen/progesterone. When administered, Nafarelin has the purpose of causing increase estrogen that will negatively feed back upon hypothalamus to decrease GnRH ( negative feedback loop ) Through negative feedback, Nafarelin causes a decrease in pituitary secretion of gonadotropins lu...
T76048 TAK-683 acetate

TAK-683 acetate是一种高效的KISS1R激动剂(IC50=170 pM),改善了代谢稳定性。作为九肽metastin的类似物,对人和大鼠的EC50值分别为0.96 nM和1.6 nM。该化合物通过消耗下丘脑GnRH,能够降低血浆FSH、LH、睾酮水平,展示了对研究激素依赖性前列腺癌的潜力。
T70309 Dicetrorelix pamoate

Others Others
Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently lutein...
T70670 TAK-448 TFA

Others Others
TAK-448 is an investigational oligopeptide analog of kisspeptin and a potent agonist of the GPR54 receptor. In animals, acute TAK-448 administration stimulates LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. TAK-448 has exhibited potent antitumor activity in rat androgen-dependent prostate cancer models. Therefore, TAK-448 may be useful in the treatment of PC in humans..
T71149 Triptorelin pamoate

Others Others
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, es...
T68292 GTX-758

Others Others
GTX-758, also known as Capesaris, is a n orally available, nonsteroidal selective estrogen receptor (ER) alpha agonist with potential antineoplastic activity. Upon administration of GTx-758, this agent suppresses the secretion of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the pituitary gland through feedback inhibition. In males, the inhibition of LH secretion prevents the synthesis of androgens, including testosterone, by the testes. This may result in ...
T85273 Gonadorelin acetate

Others Others
Gonadorelin, a gonadotropin-releasing hormone receptor (GNRHR; Ki= 13 nM in CHO cells expressing the human receptor) agonist and tropic hormone, effectively stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from rat anterior pituitary cultures at 0.1 μg doses. Additionally, it triggers LH release from bovine anterior pituitary cultures at a 1 μM concentration. In vivo, gonadorelin induces ovulation in rats pretreated with fluphenazine (ED50= 610.3 ng/kg). ...
T81270 Ripafollitropin alfa (bovine)

Ripafollitropin alfa (bovine)为一种结合了重组促卵泡激素(FSH)与绒毛膜促性腺激素(HCG)的融合蛋白。
T76047 TAK-683 TFA

TAK-683 TFA是一种高效的全KISS1R激动剂(IC50=170 pM),拥有较好的代谢稳定性,是九肽metastin的类似物,对KISS1R有激动效应,其对人和大鼠EC50值分别为0.96 nM和1.6 nM。TAK-683 TFA能够降低下丘脑GnRH水平,进而减少血浆FSH、LH、睾酮的浓度,显示出对激素依赖性前列腺癌研究的可能性。
T35794 Kisspeptin-54 (human) (trifluoroacetate salt)

Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gene KISS-1. Kisspeptin-54 induces calcium mobilization in CHO-K1 cells expressing rat and human receptors (EC50s = 1.39 and 5.47 nM, respectively). It also induces arachidonic acid release in CHO cells expressing rat and human GPR54 in a concentration-dependent manner. Kisspeptin-5...

化合物

Fsh receptor-binding inhibitor fragment(bi-10)
Cat.No: T76566
Synonym:
Target:
MHY1485
Cat.No: T1908
Synonym:
Target: mTOR, Autophagy
Relugolix
Cat.No: T3630
Synonym: RVT-601,瑞卢戈利,TAK-385
Target: GNRH Receptor
hFSH-β-(33-53) (TFA)
Cat.No: T76222
Synonym:
Target:
FSHR agonist 1
Cat.No: T72835
Synonym:
Target: Others
GnRH-I acetate
Cat.No: TP1342L
Synonym: GnRH-I acetate(33515-09-2 free base)
Target: Others
Antide acetate
Cat.No: T9380L
Synonym: 安替肽,Antide acetate (112568-12-4 Free base)
Target: LHRH
Cetrorelix diacetate
Cat.No: T5520L
Synonym: NS-75A,醋酸西曲瑞克,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate
Target: GNRH Receptor
Nafarelin acetate(76932-56-4 free base)
Cat.No: T21309
Synonym: RS-94991-298,醋酸萘法瑞林,Nafarelin acetate,Nafarelin acetate hydrate,Synarel
Target: GNRH Receptor
Triptorelin acetate(57773-63-4 free base)
Cat.No: T21410
Synonym: 醋酸曲普瑞林,Wy 42422,Triptorelin Acetate,CL 118532,AY 25650,CL 118,532,Wy 42462,BIM 21003
Target: GNRH Receptor
Norgestrel
Cat.No: T2597
Synonym: 甲基炔诺酮,SH-850,FH 122-A,炔诺孕酮,WY-3707,SH-70850
Target: Estrogen/progestogen Receptor, Reactive Oxygen Species
Glp-His-Pro-Gly-NH2
Cat.No: T82307
Synonym: pGlu-His-Pro-Gly-NH2
Target:
(D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH
Cat.No: T76620
Synonym:
Target:
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH
Cat.No: T76615
Synonym:
Target:
[Lys8] LH-RH
Cat.No: T83489
Synonym:
Target:
FW 34569
Cat.No: T25443
Synonym: FW-34-569,FW34569,FW 34-569,FW-34569,FW34-569
Target: Others
[D-Phe2,D-Ala6]-LH-RH
Cat.No: T83498
Synonym: Wy 18185
Target:
Follicle-stimulating hormone
Cat.No: T78515
Synonym:
Target: Others
Clomifene
Cat.No: T21375
Synonym: Omifin,D,Chloramiphene,Clomiphene,Clomiphene free base,Citrate
Target: Others
Org 43553
Cat.No: T63572
Synonym:
Target: Others
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
Cat.No: T76616
Synonym:
Target:
Human follicular gonadotropin releasing peptide
Cat.No: T82162
Synonym: hF-GRP
Target:
Prolactin-Releasing Peptide (1-31) (rat)
Cat.No: T81390
Synonym:
Target:
Nafarelin acetate hydrate
Cat.No: T68525
Synonym:
Target: Others
TAK-683 acetate
Cat.No: T76048
Synonym:
Target:
Dicetrorelix pamoate
Cat.No: T70309
Synonym:
Target: Others
TAK-448 TFA
Cat.No: T70670
Synonym:
Target: Others
Triptorelin pamoate
Cat.No: T71149
Synonym:
Target: Others
GTX-758
Cat.No: T68292
Synonym:
Target: Others
Gonadorelin acetate
Cat.No: T85273
Synonym:
Target: Others
Ripafollitropin alfa (bovine)
Cat.No: T81270
Synonym:
Target:
TAK-683 TFA
Cat.No: T76047
Synonym:
Target:
Kisspeptin-54 (human) (trifluoroacetate salt)
Cat.No: T35794
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2S2108 Coixol

薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA

Others; Antibacterial Microbiology/Virology; Others
Coixol (MBOA) 是一种从薏苡仁中提取的多酚,有抗菌和抗肿瘤作用。

天然产物

Coixol
Cat.No: T2S2108
Synonym: 薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA
Target: Others, Antibacterial
Cat. No. Product Name Species Expression System
TMPY-04866 FSH alpha & FSH beta Protein, Human, Recombinant (hFc)

FSH α & FSH β,FSH α& FSH...

Human HEK293 Cells
FSH alpha & FSH beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.7 kDa and the accession number is NP_000726.1&NP_000501.1.
TMPY-00091 FSH Beta Protein, Human, Recombinant (His)

HH24,FSH β,follicle stimulating hormone, β polypept...

Human HEK293 Cells
FSH Beta Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.9 kDa and the accession number is A0A0F7RQE8.
TMPY-04890 FSH Beta Protein, Human, Recombinant (hFc)

follicle stimulating hormone, beta polypeptide,follicle stim...

Human HEK293 Cells
FSH Beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is A0A0F7RQE8.
TMPK-01020 FSHB Protein, Mouse, Recombinant (hFc)

FSH-beta,FSH-B,FSHB,FSH-...

Mouse HEK293 Cells
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Mouse, Recombinant (hFc) is expressed in HE...
TMPK-01285 FSHB Protein, Cynomolgus, Recombinant (His)

Follitropin,FSH-B,FSH-beta,FSH-β,...

Cynomolgus HEK293 Cells
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Cynomolgus, Recombinant (His) is expressed ...
TMPY-04586 Chorionic Gonadotropin/CGA Protein, Human, Recombinant

FSH alpha,glycoprotein hormones, alpha polypeptide,...

Human HEK293 Cells
Chorionic Gonadotropin/CGA Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 10.2 kDa and the accession number is P01215.
TMPY-00647 Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His)

CG-α,FSH alpha,glycoprotein hormones, alpha polypep...

Human HEK293 Cells
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.6 kDa and the accession number is P01215.
TMPY-02923 Chorionic Gonadotropin/CGA Protein, Human, Recombinant (mFc)

HCG,GPHa,CG-ALPHA,glycoprotein hormones, alpha polypeptide,g...

Human HEK293 Cells
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 36.6 kDa and the accession number is P01215.
TMPH-01348 FSHR Protein, Human, Recombinant (His)

Follitropin receptor,FSHR,Follicle-stimulating horm...

Human HEK293 Cells
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 43.5 kDa and the accession number is P23945.
TMPH-01347 FSHR Protein, Human, Recombinant (E. coli, His)

Follicle-stimulating hormone receptor,Follitropin receptor,<...

Human E. coli
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.0 kDa and the accession number is P23945.
TMPJ-01471 Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant

Activin A,INHBA,Inhibin beta A chain,Inhibin β A chain

Human/Mouse/Rat HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell developm...
TMPY-05176 AMH Protein, Human, Recombinant (His)

MIS,anti-Mullerian hormone,MIF

Human HEK293 Cells
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi...
TMPY-01190 INHBB Protein, Human, Recombinant (His)

inhibin beta B,INHBB,Inhibin β B Protein,MGC157939,inhibin β...

Human HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two ß subunits, ßA ßA (activin A), ßB ßB (activin B), or ßA ßB (activin AB). Inhibin is composed of an alpha and one of two ß subunits, ßA (inhibin A) or ßB (inhibin B). Activins are produced in...
TMPY-01846 Activin A Protein, Mouse, Recombinant (His)

inhibin, β A,inhibin, beta A

Mouse HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in...
TMPY-04307 GNRH2 Protein, Human, Recombinant (hFc)

LH-RHII,gonadotropin releasing hormone 2,GnRH-II,GNRH2

Human HEK293 Cells
GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleaved to form neuropeptides which, in part, regulate reproductive functions by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). 3 alternatively spliced human isoforms have been reported. The second mammalian...

重组蛋白

FSH alpha & FSH beta Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04866
Species: Human
Expression System: HEK293 Cells
FSH Beta Protein, Human, Recombinant (His)
Cat.No: TMPY-00091
Species: Human
Expression System: HEK293 Cells
FSH Beta Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04890
Species: Human
Expression System: HEK293 Cells
FSHB Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01020
Species: Mouse
Expression System: HEK293 Cells
FSHB Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01285
Species: Cynomolgus
Expression System: HEK293 Cells
Chorionic Gonadotropin/CGA Protein, Human, Recombinant
Cat.No: TMPY-04586
Species: Human
Expression System: HEK293 Cells
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His)
Cat.No: TMPY-00647
Species: Human
Expression System: HEK293 Cells
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (mFc)
Cat.No: TMPY-02923
Species: Human
Expression System: HEK293 Cells
FSHR Protein, Human, Recombinant (His)
Cat.No: TMPH-01348
Species: Human
Expression System: HEK293 Cells
FSHR Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01347
Species: Human
Expression System: E. coli
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Cat.No: TMPJ-01471
Species: Human/Mouse/Rat
Expression System: HEK293 Cells
AMH Protein, Human, Recombinant (His)
Cat.No: TMPY-05176
Species: Human
Expression System: HEK293 Cells
INHBB Protein, Human, Recombinant (His)
Cat.No: TMPY-01190
Species: Human
Expression System: HEK293 Cells
Activin A Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01846
Species: Mouse
Expression System: HEK293 Cells
GNRH2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04307
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIJ-0268 Relugolix-d6

Relugolix-d6 是 Relugolix 的氘代化合物。Relugolix 的 CAS 号为 737789-87-6。Relugolix 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比,它对人和猴子的受体具有高亲和力和强拮抗活性,它们的IC50值分别为0.33 nM和0.32 nM。它可用于研究性激素依赖性疾病,如子宫肌瘤、子宫内膜异位症、前列腺癌等。

同位素标记化合物

Relugolix-d6
Cat.No: TMIJ-0268
Synonym:
Target:
TargetMol Loading
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