141
7
2
76
Cat. No. | Product Name | ||
---|---|---|---|
LF9100 | 丝氨酸靶向共价抑制剂库 | 2700 compounds | |
Over 2,700 small-molecule screening compounds in the library. | |||
DO2200 | 共价抑制剂库CD | 12000 compounds | |
数量多:超过12000种共价结合化合物,并且数量在持续增加; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T32907 |
L-Topaquinone
L-Topaquinone residue,2',4',5'-Topaquinone |
Others | Others |
L-Topaquinone is a metabolite of dopaquione, an important intermediate in melanogenesis. | |||
T9344 |
3-Amino-2-oxazolidinone
|
Others; Endogenous Metabolite | Metabolism; Others |
3-Amino-2-oxazolidinone 是一种呋喃唑烷酮的代谢物 (metabolite),可用作检测呋喃唑烷酮残留的一个指标。 | |||
T8375 |
ML-210
CID 49766530 |
Ferroptosis; GPX; Glutathione Peroxidase; Ras | Apoptosis; GPCR/G Protein; MAPK; Metabolism; oxidation-reduction |
ML-210 (CID 49766530) 是一种共价的选择性谷胱甘肽过氧化物酶 4 (GPX4) 抑制剂,EC50为 30 nM。它与 GPX4 硒代半胱氨酸残基结合,具有抗癌活性。 | |||
T3088 |
N-Ethylmaleimide
1-Ethyl-1H-pyrrole-2,5-dione,n-乙基马来酰亚胺,Ethylmaleimide,NEM |
Cysteine Protease; DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination |
N-Ethylmaleimide (NEM) 是烷基化自由巯基的试剂, 是一种半胱氨酸蛋白酶抑制剂,用于实验生化研究。它也是一种去泛素化酶抑制剂,特异性抑制线粒体中的磷酸盐转运。 | |||
TP1773L |
PGLa acetate
|
Antibacterial; Antibiotic | Microbiology/Virology |
PGLa acetate 是 magainin 抗生素肽家族的 21 个残基成员。 | |||
TP1410 |
Cecropin A
|
Antibacterial; Antibiotic | Microbiology/Virology |
Cecropin A 是37个氨基酸组成的线性多肽,表现出抗菌、抗炎和抗肿瘤的功效。 | |||
TP1775L |
LL-37, Human acetate(154947-66-7 free base)
|
Antibacterial | Microbiology/Virology |
LL-37, Human acetate(154947-66-7 free base) 是一种 37 个残基、两亲性、cathelicidin 衍生的抗菌肽,具有广谱的抗菌活性。 | |||
T29955 |
AMC-01
AMC01,AMC 01 |
Antiviral; PERK | Apoptosis; Immunology/Inflammation |
AMC-01 具有潜在的抗病毒活,可通过丝氨酸残基 51 的磷酸化诱导 eIF2-α 失活,这种作用具有剂量和时间依赖性。AMC-01 可用来研究动脉粥样硬化和帕金森综合征。 | |||
TP1365L |
Parasin I acetate(219552-69-9 free base)
|
Antibacterial | Microbiology/Virology |
Parasin I acetate(219552-69-9 free base) 是一种从受伤鲶鱼 (Parasilurus asotus) 的皮肤粘液中分离出来的 19 个残基的强效抗菌肽。 | |||
TP1737L |
Urotensin II (114-124), human acetate
Urotensin II (114-124), human acetate(251293-28-4 free base) |
GPR | Endocrinology/Hormones; GPCR/G Protein |
Urotensin II (114-124), human acetate(251293-28-4 free base) 是一种 11 个氨基酸残基肽,是一种有效的血管收缩剂和孤儿受体 GPR14 的激动剂。 | |||
T3175 |
LDHA-IN-4
AZ 33,AZ-33,LDHA Inhibitor,AZ33 |
Dehydrogenase | Metabolism |
LDHA-IN-4 (AZ33) 是乳酸脱氢酶 A 选择性抑制剂,IC50=0.5 μM,Kd=0.093 μM。 | |||
T38766L |
Histone H3 (1-35) acetate
|
Others | Others |
Histone H3 (1-35) acetate 是组蛋白 H3 的 35 个残基肽。组蛋白 H3 是一种重要的蛋白质,在基因的动态和长期调控中发挥作用。 | |||
TP2057L |
Camstatin acetate
|
NO Synthase | Immunology/Inflammation |
Camstatin acetate 结合钙调蛋白并抑制神经元一氧化氮合酶。它是 PEP-19 的单一钙调蛋白结合 IQ 基序的具有功能活性的 25 个残基片段。 | |||
T5146 |
Eptifibatide acetate (148031-34-9 free base)
Eptifibatide acetate,依菲巴特醋酸盐 |
Others | Others |
Eptifibatide acetate (148031-34-9 free base) (Eptifibatide acetate) 是一种糖蛋白 IIb/IIIa 抑制剂类的抗血小板药物,是一种由 6 个氨基酸和一个巯基丙酰基残基构成的环状七肽。 | |||
TP1275 |
3X FLAG peptide TFA (402750-12-3 free base)
3X FLAG peptide TFA |
Others | Others |
3X FLAG peptide TFA (402750-12-3 free base) (3X FLAG peptide TFA) 是一种含有 23 个氨基酸残基的合成肽。 Asp-Tyr-Lys-Xaa-Xaa-Asp 基序在肽中重复了 3 次。 | |||
T15735 |
Leptomycin B
CI 940,LMB,来普霉素B |
CRM1; Antibiotic; Antifungal | Membrane transporter/Ion channel; Microbiology/Virology |
Leptomycin B (LMB) 是一种抗真菌抗生素,可阻断真核细胞周期,抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使 CRM1/exportin 1失活。它 | |||
TP1143L |
Fibrinopeptide A, human acetate
Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate |
Others | Others |
Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate)(25422-31-5 free base) 是一种 16 个残基的短多肽,由凝血酶从纤维蛋白原上切割下来。纤维蛋白肽 A (FPA) 由纤维蛋白原蛋白的 N 末端 Aα 区域在被凝血酶切割后产生。 | |||
TP1120L |
IRBP acetate(211426-18-5 free base)
Interphotoreceptor Retinoid Binding Protein Fragment IRBP |
Others | Others |
IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) 是一种含有 20 个残基的肽,是一种主要的致病表位。它存在于间质视觉色素结合蛋白肽(IRBP 161-180)的第一个同源重复序列中,可诱导葡萄膜炎后(EAU)。 | |||
T1006 |
Propantheline bromide
Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl |
AChR | Neuroscience |
Propantheline bromide (Pro-Banthine) 是一种抗毒蕈碱剂,用于研究多汗症,遗尿,胃肠和膀胱痉挛。 | |||
T17731L |
CL2A-SN-38 DCA 1279680-68-0(free base)
|
Others | Others |
CL2A-SN-38 DCA 1279680-68-0(free base) 是一种药物-接头偶联物,由有效的 DNA 拓扑异构酶 I 抑制剂 SN-38 和接头 CL2A 组成,用于制造抗体药物偶联物 (ADC)。CL2A-SN-38 由有效的 DNA 拓扑异构酶组成I 抑制剂 SN-38 和接头 CL2A 以制造抗体药物偶联物 (ADC)。 CL2A-SN-38 对一系列人类实体瘤类型提供显着和特异性的抗肿瘤作用。 CL2A 是一种不可切割的复杂 PEG8 和含有三唑的 PABC-肽-mc 接头。 CL2A 可通过 pH 敏感性裂解,产生旁观者效应,并通过二硫键在半胱氨酸残基处结合抗体。 | |||
TP2475 |
Kemptamide
|
||
Kemptamide is a synthetic peptide with 13-residue. | |||
TP1282 |
PLP (139-151)
PLP 139-151 |
||
PLP (139-151) is amino acid residue residue 139 to 151 of myelin proteolipid protein (PLP). This peptide is used to induce relapsing-remitting (RR)-EAE model. | |||
T19178 |
ACPK
|
Others | Others |
ACPK is a pyrrolysine analogue bearing an azide residue. | |||
T32548 |
Laminin B1 (1363-1383)
Yosh4,Yosh 4,Yosh-4 |
Others | Others |
Laminin B1 (1363-1383) is the Residue 1363-1383 of the laminin B1 chain. | |||
T20933 |
Bis(p-chlorophenyl)acetic acid
Bis(p-chlorphenyl)essigsaeure,Bis(4-chlorophenyl)acetic acid,DDA (degradation product),DDA |
Others | Others |
Bis(p-chlorophenyl)acetic acid is a standard for pesticide residue analysis. | |||
TP1830 |
SV40 large T antigen NLS
|
||
SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55. | |||
T41204 |
TAT-Gap19(I130A)
TAT-Gap19(I130A) |
Others | Others |
TAT-Gap19(I130A) is a control peptide for TAT-Gap19, a Cx43 hemichannel blocker. TAT-Gap19(I130A) consists of TAT-GAP19 with a I130A amino acid residue change at a key residue for GAP19 activity. In C6 glioma cells expression Cx43, TAT-GAP19(1130A) does not inhibit [Ca2+]i-triggered ATP release at 200 μM. TAT-Gap19(I130A) is cell permeable. | |||
TP2449 |
Argipressin, ala(10)-
|
||
Argipressin, ala(10)- is a Decapeptide that differs from argipressin in the addition of an N-terminal Ala-residue. | |||
T31171 |
D714
D-714,D 714 |
Others | Others |
D714 is a weakly conserved palm subdomain residue (located far from the catalytic center) that, when replaced by alanine, impains the enzyme's replication in vivo and in vitro. | |||
TP1142 |
Fibrinopeptide A, human TFA
Human fibrinopeptide A TFA |
||
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which b | |||
T40528 |
Oxytocin free acid
9-Deamidooxytocin |
||
Oxytocin free acid, also known as 9-Deamidooxytocin, is an analog of oxytocin where the glycinamide residue at position 9 has been substituted with a glycine residue. Oxytocin, a pleiotropic peptide hormone, has wide-ranging implications for general health, adaptation, development, reproduction, and social behavior. | |||
TP1136 |
Secretin (28-54), human
Human secretin |
||
Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors. | |||
TP1394 |
{Val1}-Exendin-3/4
|
||
{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide. | |||
T28135 |
NC043
NC 043,NC-043 |
Others | Others |
NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF. | |||
TP1415 |
Urotensin II (114-124), human TFA
|
||
Urotensin II (114-124), human TFA, is an 11-amino acid residue peptide with a strong vasoconstrictor effect. This compound acts as an agonist for the orphan receptor GPR14. | |||
T38766 |
Histone H3 (1-35)
Histone H3 (1-35) |
||
Histone H3 (1-35) is a 35-residue peptide derived from histone H3, which is a key member of the five main histones participating in the formation of chromatin within eukaryotic cells. | |||
TP1745 |
Ceratotoxin A
|
||
Ceratotoxin A is a 29-residue peptide extracted from the accessory gland secretion fluid, known for its potent antibacterial properties. | |||
T69080 |
T1001
|
Others | Others |
T1001 is an antagonist of hypoxia-inducible factor-2α subunit (HIF-2α) which displaces residue M252 from inside the HIF-2α PAS-B pocket toward the ARNT subunit to weaken heterodimerization. | |||
TP1775 |
LL-37, Human
|
||
LL-37, Human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. | |||
TP1689 |
TAT (48-57) TFA(253141-50-3,free)
TAT (48-57) TFA |
||
TAT (48-57) (TFA) is a cellular permeability peptide derived from hiv-1 transcriptional activator (TAT) protein residue 48-57. | |||
TP1776 |
HIV-1 TAT 48-60
|
||
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. This is one of the cell-penetrating peptides generated from the human immunodeficient virus -1 Tat protein residue 48-60. | |||
T82394 |
FLAG-Cys
|
||
FLAG-Cys为带有Cys残基的FLAG肽,具有免疫原性。 | |||
TP1699 |
SEB Domain (144-153)
SEB Domain 144-153 |
||
SEB Domain (144-153) peptide is Staphylococcal Enterotoxin B domain amino acid residue 163-172. SEB Domain (144-153) has been shown to inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1. | |||
TP1119 |
Interphotoreceptor retinoid-binding protein(668-687)
IRBP(668-687) |
||
Interphotoreceptor retinoid-binding protein(668-687)is an amino acid residue of human retinoid-binding protein(IRBP) 668-687, which can induce uveitis. | |||
TP1737 |
Urotensin II (114-124), human
|
||
Urotensin II (114-124), human, is an 11-amino acid residue peptide that exhibits strong vasoconstrictor activity and acts as an agonist for the orphan receptor GPR14. | |||
T15585 |
IRBP(668-687) (TFA)
Interphotoreceptor retinoid-binding protein(668-687) TFA |
Others | Others |
Interphotoreceptor retinoid-binding protein TFA is the amino acid residue 668 to 687 of human interphotoreceptor retinoid-binding protein (IRBP). It also induces uveitis. | |||
TP1358 |
Peptide M
|
||
Peptide M is a synthetic Peptide, 50 aa, derived from streptococcus M protein, containing an additional c-terminal cysteine residue. | |||
TP1462 |
MART-1 (26-35) (human) TFA (156251-01-3 free base)
MART-1 (26-35) (human) TFA |
||
MART-1 (26-35) (human) TFA is an amino acid residue of 26-35 protein. | |||
TP2163 |
SEB Domain 144-153 TFA(210229-94-0 free base)
SEB Domain (144-153) (TFA) |
Others | Others |
SEB Domain 144-153 TFA is Staphylococcal Enterotoxin B domain amino acid residue 144-153. It inhibits transcytosis of multiple staphylococcal enterotoxins, SEE, SEA, and TSST-1. | |||
T31218 |
DBHDA
|
Others | Others |
DBHDA is a reagent to convert a Cys into a Dha moiety by reacting with a C-terminal Cys residue and thus allowing the use of recombinant Ubl G76C mutants to prepare probes. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13482 |
2'-O-Methyladenosine
|
Endogenous Metabolite | Metabolism |
2'-O-Methyladenosine 是甲基化腺嘌呤的残基,在正常人群和腺苷脱氨基酶缺乏病人的尿液中均可被检测到。它显示出独特的降血压活性。 | |||
T5055 |
For-Met-OH
fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine |
Others; Endogenous Metabolite | Metabolism; Others |
For-Met-OH (N-Formyl-L-methionine) 是内源性代谢产物的一种。 | |||
T67867 |
Mycaminosyltylonolide
|
Antibacterial | Microbiology/Virology |
Mycaminosyltylonolide 是一种大环内酯类抗生素,它是 tyololide 在位置5上具有β - d -mycaminosyl 残基。Mycaminosyltylonolide 是一种有效的抗生素,具有抗菌活性和抑制荧光素酶的合成。 | |||
T6599 |
N6-methyladenosine
N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A |
Others; Influenza Virus; Endogenous Metabolite | Metabolism; Microbiology/Virology; Others |
N6-Methyladenosine 是甲基化的腺嘌呤残基,苷是转移核糖核酸降解的内源性尿核苷产物。它是存在于所有高等真核生物中最普遍的的信使 RNA 内部修饰,可修饰病毒 RNA,有抗病毒活性。 | |||
T83341 |
3α,4β-Galactotriose
|
||
3α,4β-Galactotriose为一种半乳糖类化合物。 | |||
T75974 |
Cecropin A TFA
|
Others | Others |
Cecropin A TFA 是由 37 个氨基酸残基构成的线性抗菌肽,从 Hyalaphora cecropiapupae 得到,具有抗菌、抗炎和抗癌作用。 | |||
T82032 |
Isoglobotriaose
Gala-3Galb-4Glc |
||
Isoglobotriaose (Gala-3Galb-4Glc)是哺乳动物组织中的一种糖鞘脂,属于球状三脂糖的类似物。其神经节苷脂衍生物isoglobotriaosylceramide特定分布于小肠非上皮细胞的残基中,而globotriaosylceramide则在两种细胞隔室中都有分布。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02625 |
DLAT Protein, Mouse, Recombinant (E. coli, His)
Dihydrolipoyllysine-residue acetyltransferase compo... |
Mouse | E. coli |
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. DLAT Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 62.8 kDa and the accession number is Q8BMF4. | |||
TMPH-00667 |
OGDC-E2 Protein, E. coli O157:H7, Recombinant (His)
Dihydrolipoamide succinyltransferase component of 2-oxogluta... |
E. coli | E. coli |
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). OGDC-E2 Protein, E. coli O157:H7, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P0AFG7. | |||
TMPH-02626 |
DLAT Protein, Mouse, Recombinant (His)
Pyruvate dehydrogenase complex component E2,Dlat,Dihydrolipo... |
Mouse | HEK293 Cells |
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | |||
TMPJ-01065 |
Noggin/NOG Protein, Mouse, Recombinant (His)
Nog,Noggin |
Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi... | |||
TMPY-03650 |
BirA Protein, E. coli, Recombinant (His & MBP)
BirA,dhbB,bioR |
E. coli | E. coli |
The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these proteins to be tetramerized by binding to streptavidin. Because of the specificity of the biotinylation at the C terminus, the orientation of the membrane proteins on the streptavidin is equivalent to that of the native protein on the cell surface. These tetrameric proteins can be use... | |||
TMPY-04544 |
MEK2 Protein, Human, Recombinant (GST)
mitogen-activated protein kinase kinase 2,FLJ26075,MKK2,CFC4... |
Human | Baculovirus Insect Cells |
Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion ... | |||
TMPK-00986 |
IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)
SCIDX1,IL2RG,gammaC,γC,CIDX,IL-2 R γ/CD132,IL-2 R gamma,SCID... |
Cynomolgus | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant... | |||
TMPK-00238 |
IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)
CD132,gammaC,γC,IMD4,IL2RG,SCIDX1,CIDX,IL-2 R γ,P64,SCIDX,IL... |
Human | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Human, Recombinant (His... | |||
TMPK-00987 |
IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-2 R γ/CD132,IL-2 R gamma,IMD4,gammaC,SCIDX1,CD132,SCIDX,I... |
Cynomolgus | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein (Primary Amine Labeling)... | |||
TMPK-00239 |
IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated
SCIDX,IMD4,IL-2 R gamma,CD132,SCIDX1,IL-2 R γ/CD132,γC,CIDX,... |
Human | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Human, Recombinant (His... | |||
TMPH-02343 |
Hypodermin-A Protein, Hypoderma lineatum, Recombinant (His)
Hypodermin-A |
Hypoderma lineatum | E. coli |
Specificity, limited to carboxyl side of arginine residue in B-chain of insulin. | |||
TMPJ-00326 |
CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated
IL-2R subunit beta,High affinity IL-2 receptor subunit β,Int... |
Human | HEK293 Cells |
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit c... | |||
TMPY-03810 |
GALNT2 Protein, Human, Recombinant (His)
GalNAc-T2,polypeptide N-acetylgalactosaminyltransferase 2 |
Human | HEK293 Cells |
GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. GALNT2 may play a role in lipid metabolism. It catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT2 has a broa... | |||
TMPH-02679 |
QPCT Protein, Mouse, Recombinant (His)
Glutaminyl cyclase,Glutaminyl-tRNA cyclotransferase,Qpct,Glu... |
Mouse | P. pastoris (Yeast) |
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is Q9CYK2. | |||
TMPH-02256 |
Trypsin-3 Protein, Human, Recombinant (His)
Trypsin III,Mesotrypsinogen,PRSS3,Trypsin-3,Serine protease ... |
Human | E. coli |
Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. | |||
TMPJ-00982 |
DHS Protein, Human, Recombinant (His)
DS,Deoxyhypusine Synthase,DHPS,DHS |
Human | E. coli |
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | |||
TMPJ-00052 |
Leptin Protein, Mouse, Recombinant
OB,Obesity Factor,OBS,LEP,Obese Protein,Leptin |
Mouse | E. coli |
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin defici... | |||
TMPH-02680 |
QPCT Protein, Mouse, Recombinant (His & Myc)
Glutaminyl cyclase,Qpct,Glutaminyl-peptide cyclotransferase,... |
Mouse | HEK293 Cells |
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-6xHis-Myc tag. The predicted molecular weight is 41.6 kDa and the accession number is Q9CYK2. | |||
TMPH-01622 |
KDM3B Protein, Human, Recombinant (His & Myc & SUMO)
[histone H3]-dimethyl-L-lysine(9) demethylase 3B,Lysine-spec... |
Human | E. coli |
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. | |||
TMPH-01613 |
LIPT1 Protein, Human, Recombinant (His)
Lipoate biosynthesis protein,Lipoyl amidotransferase LIPT1, ... |
Human | E. coli |
Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes. | |||
TMPJ-00811 |
IGFBP-1 Protein, Human, Recombinant (His)
Insulin-like growth factor-binding protein 1,PP12,IGFBP-1,IG... |
Human | HEK293 Cells |
Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Regulation of Insulin-like Growth Factor (IGF) transp... | |||
TMPJ-01223 |
GALNTL1 Protein, Human, Recombinant (His)
UDP-GalNAc:Polypeptide N-,Polypeptide GalNAc Transferase-Lik... |
Human | HEK293 Cells |
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1, also known as Polypeptide GalNAc transferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1, GalNAC-T-like protein 1, pp-GaNTase-like protein 1 and GALNTL1, belongs to the glycosyltransferase 2 family. GALNTL1 plays an important role in the protein modification and protein glycosylation process. GALNTL1 uses the manganese and ... | |||
TMPJ-00611 |
SFP Protein, B.subtilis, Recombinant (His)
Surfactin synthase-activating enzyme,sfp,lpa-8,4'-phosphopan... |
Bacillus subtilis | E. coli |
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation. | |||
TMPH-00694 |
LolA Protein, E. coli O9:H4, Recombinant (His)
Outer-membrane lipoprotein carrier protein,lolA |
E. coli | P. pastoris (Yeast) |
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | |||
TMPY-01246 |
MARCO Protein, Mouse, Recombinant (His)
AI323439,Ly112,macrophage receptor with collagenous structur... |
Mouse | HEK293 Cells |
Macrophage receptor MARCO, also known as Macrophage receptor with collagenous structure and Marco, is a single-pass type II membrane protein. MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. It is expressed in subpopulations of macrophages in the spleen and the medullary cord of lymph nodes. Although it is expressed on subsets of macrophages, it can be upregulated on other macrophages after bacterial infection. The strategic positi... | |||
TMPH-03029 |
MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)
Peptidase M,Methionine aminopeptidase,map |
Mycoplasma pneumoniae | E. coli |
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. | |||
TMPH-00164 |
4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc)
4'-phosphopantetheinyl transferase ffp,EC:2.7.8.-,Fengycin s... |
Bacillus subtilis | E. coli |
May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. 4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.0 kDa and the accession number is Q9F4F7. | |||
TMPY-02840 |
Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
UBE1,ubiquitin-like modifier activating enzyme 1,UBA1A,SMAX2... |
Human | Baculovirus Insect Cells |
UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue w... | |||
TMPH-00688 |
YbiS Protein, E. coli O6:H1, Recombinant (His & Myc)
Probable L,D-transpeptidase YbiS,ybiS |
E. coli | E. coli |
Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp. YbiS Protein, E. coli O6:H1, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.3 kDa and the accession number is P0AAX9. | |||
TMPH-00654 |
Methionine aminopeptidase Protein, E. coli, Recombinant (His & SUMO)
Methionine aminopeptidase,map,Peptidase M |
E. coli | E. coli |
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. | |||
TMPY-01893 |
Serpin A12 Protein, Human, Recombinant (His)
OL-64,serpin peptidase inhibitor, clade A (α-1 antiproteinas... |
Human | HEK293 Cells |
Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin, in egg white), hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin) and tumor suppressor genes (maspin). Most inhibitory serpins target chymotrypsin-like serine proteases. These enzymes are defined by the presence of a nucleophilic serine residue in ... | |||
TMPH-00067 |
Venom dipeptidyl peptidase 4 Protein, Apis mellifera, Recombinant (His & Myc)
Venom dipeptidyl peptidase 4,Venom dipeptidyl peptidase IV,A... |
Apis mellifera | E. coli |
Venom dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. May process promelittin into its active form and/or modulate the chemotactic activity of immune cells after the insect sting. Venom dipeptidyl peptidase 4 Protein, Apis mellifera, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.4 kDa and the... | |||
TMPJ-01229 |
SUMF1 Protein, Human, Recombinant (His)
C-Alpha-Formylglycine-Generating Enzyme 1,FGE,C-α-Formylglyc... |
Human | HEK293 Cells |
Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known. | |||
TMPY-01855 |
Serpin A10 Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase,... |
Mouse | HEK293 Cells |
Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPINA1 / Serpin-A1 inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because ... | |||
TMPJ-00872 |
MGMT Protein, Human, Recombinant (His)
MGMT,6-O-methylguanine-DNAmethyltransferase,O-6-methylguanin... |
Human | E. coli |
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyzes the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-met... | |||
TMPK-01242 |
MD2/LY96 Protein, Human, Recombinant (His)
MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY96,ESOP1 |
Human | E. coli |
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1. | |||
TMPH-01250 |
MAP2K3 Protein, Human, Recombinant (His & SUMO)
MAP2K3,MAPK/ERK kinase 3,Dual specificity mitogen-activated ... |
Human | E. coli |
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. MAP2K3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.3 kDa and the accession numbe... | |||
TMPH-03018 |
MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)
Peptidase M,map-1,Methionine aminopeptidase 1 |
Mycobacterium tuberculosis | E. coli |
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.9 kDa and the accession ... | |||
TMPK-00632 |
MD2/LY96 Protein, Cynomolgus, Recombinant (His)
ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2 |
Cynomolgus | E. coli |
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0. | |||
TMPY-03959 |
CHST11 Protein, Human, Recombinant (His)
carbohydrate (chondroitin 4) sulfotransferase 11,HSA269537,C... |
Human | Baculovirus Insect Cells |
CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with ... | |||
TMPH-03158 |
PAD Protein, Porphyromonas gingivalis, Recombinant (His)
Peptidylarginine deiminase |
Porphyromonas gingivalis | E. coli |
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. PAD Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weig... | |||
TMPK-01027 |
IGFBP-7 Protein, Mouse, Recombinant (hFc)
TAF,RAMSVPS,IBP7,PSF,IGFBP-7,MAC25,IGFBPRP1,AGM,FSTL2,IGFBP-... |
Mouse | HEK293 Cells |
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Mouse, Recombinant (hFc) is expres... | |||
TMPH-02529 |
ASGR2 Protein, Mouse, Recombinant (His & Myc)
ASGPR 2,HL-2,mHL-2,Asgr-2,Hepatic lectin 2,ASGP-R 2,Asialogl... |
Mouse | E. coli |
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. ASGR2 Protein, Mouse, Recombinant (His & Myc) is expressed ... | |||
TMPH-02180 |
TTBK2 Protein, Human, Recombinant (His & Myc)
Tau-tubulin kinase 2,TTBK2 |
Human | E. coli |
Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro. | |||
TMPJ-01301 |
GGACT Protein, Human, Recombinant (His)
Gamma-Glutamylaminecyclotransferase,A2LD1,AIG2-Like Domain-C... |
Human | E. coli |
Gamma-Glutamylaminecyclotransferase is an enzyme that converts gamma-glutamylamines to free amines and 5-oxoproline which belongs to the gamma-glutamylcyclotransferase family. It shows high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and contributes to degradation of proteins cross-linked by transglutaminases. It degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. This pro... | |||
TMPK-00874 |
Thyroid Peroxidase Protein, Mouse, Recombinant (His)
MK-CSF,MGDF,ML,MPLLG,THPO,TPOMKCSF,Thrombopoietin,MKCSF,MGDF... |
Mouse | HEK293 Cells |
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune t... | |||
TMPJ-00220 |
B3GAT1 Protein, Human, Recombinant (His)
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)... |
Human | HEK293 Cells |
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. It adds a glucuronic residue to the terminal lactosamine residue (Gal beta 14GlcNAc) of a glycoprotein or glycolipid, which can be further sulfated to become the HNK1 epitope, a unique trisaccharide structure, HSO3-3GlcA beta 1-3Gal beta 1-4GlcNAc. The enzyme activity was found to be enhanced in the presence of sphingomyelin an... | |||
TMPK-01371 |
IGFBP-7 Protein, Human, Recombinant (hFc)
RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7v,IGFBP-7,PSF,FST... |
Human | HEK293 Cells |
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres... | |||
TMPH-03248 |
ASGR1 Protein, Rat, Recombinant (His & Myc)
Asialoglycoprotein receptor 1,ASGP-R 1,rHL-1,Asgr1,HL-1,Asgr... |
Rat | HEK293 Cells |
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. ASGR1 Protein, Rat, Recombinant (His & Myc) is expressed in... | |||
TMPH-02539 |
MGAT3 Protein, Mouse, Recombinant (His & Myc)
Mgat3,Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosam... |
Mouse | E. coli |
It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains, called bisecting N-acetylglucosamine (GlcNAc). It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. The addition of this bisecting GlcNAc residue alters not only the composition,... | |||
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