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Search Results for " protein tyrosine phosphatase "

Targets Recommended: Antibacterial Antibiotic

69

抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0827	Cefsulodin sodium Cefsulodine sodium,Sulcephalosporin,头孢磺啶钠	Antibacterial; Antibiotic	Microbiology/Virology
	Cefsulodin sodium (Sulcephalosporin) 是β内酰胺抗生素，对缘脓杆菌和肠杆菌有活性。
T7541	PTP inhibitor 1 PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮	Phosphatase	Metabolism
	PTP inhibitor 1 是蛋白酪氨酸磷酸酶 (PTP) 抑制剂，具有抗血管生成作用。
T2160	Suramin Sodium Salt 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060	Apoptosis; Phosphatase; SARS-CoV; Sirtuin; Reverse Transcriptase; Topoisomerase; Parasite	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K，是抗寄生虫，抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂，也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。
T12578	(E,E)-RAMB4 PTP1B-IN-8	Phosphatase	Metabolism
	PTP1B-IN-8 is a potent and selective inhibitor of protein tyrosine phosphatase-1B (PTP1B).
T4256	PTP1B-IN-2	Phosphatase	Metabolism
	PTP1B-IN-2 是一种蛋白酪氨酸磷酸酶抑制剂，IC50=50 nM。
T7356	PTP1B-IN-1 PTP1B inhibitor,5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物	Phosphatase	Metabolism
	PTP1B-IN-1 (PTP1B inhibitor) 是一种蛋白质酪氨酸磷酸酶 1B 的有效抑制剂 (IC50 : 1.6 mM)
T13013	Sodium stibogluconate Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠	Phosphatase	Metabolism
	Sodium stibogluconate (Stibogluconate trisodium nonahydrate) 是一种有效的蛋白酪氨酸磷酸酶 (phosphatase) 抑制剂。它在10，100 和 100 μg/mL 时分别抑制 99% 的 SHP-1，SHP-2 和 PTP1B 活性。
T31458	DiFMUP 6,8-Difluoro-4-methylumbelliferyl phosphate
	DiFMUP (6,8-Difluoro-4-methylumbelliferyl phosphate) 是一种荧光底物，抑制蛋白酪氨酸磷酸酶（PTPs），可用于检测苏氨酸磷酸酶的活性。
T7381	TCS 401	Phosphatase	Metabolism
	TCS 401 是一种选择性的蛋白酪氨酸磷酸酶 1B 抑制剂。
T13176	TNO155 Batoprotafib	Phosphatase	Metabolism
	TNO155 是具有口服活性野生型SHP2的选择性变构抑制剂 (IC50= 0.011 µM)。它有研究 RTK 依赖性恶性肿瘤（尤其是晚期实体瘤）的潜力。
T14841	BVT948	Phosphatase; P450; Histone Methyltransferase	Chromatin/Epigenetic; Metabolism
	BVT948 是一种蛋白酪氨酸磷酸酶抑制剂，还可以抑制赖氨酸甲基转移酶 SETD8 (KMT5A) 和几种细胞色素 P450 (P450) 同工型。
T67893	PTP1B-IN-22	Phosphatase	Metabolism
	PTP1B-IN-22是一种蛋白酪氨酸磷酸酶1B (PTP1B)抑制剂，可抑制骨骼肌 L6肌管的葡萄糖摄取。
T37184	CX08005 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid	Phosphatase	Metabolism
	CX08005 是一种蛋白酪氨酸磷酸酶 1B 抑制剂，可减轻与非酒精性脂肪肝相关的肝脏脂质蓄积和微循环障碍。
T10190	7-BIA	Phosphatase	Metabolism
	7-BIA 是一种受体型蛋白酪氨酸磷酸酶 D (PTPRD) 抑制剂，具有抗抗成瘾作用，可用于研究神经性疼痛。
T41298	LMPTP INHIBITOR 1 dihydrochloride	Phosphatase	Metabolism
	LMPTP INHIBITOR 1 dihydrochloride 是选择性的低分子量蛋白酪氨酸磷酸酶（LMPTP）抑制剂，抑制 LMPTP-A 活性的IC50为 0.8 μM。
T61678	MY10	Phosphatase	Metabolism
	MY10 可以减弱了类似暴饮暴食的乙醇消耗和乙醇奖励。MY10 是一种有效且具有口服活性的的受体蛋白酪氨酸磷酸酶 (RPTPβ/ζ) 抑制剂。
T7704	KY-226	Phosphatase	Metabolism
	KY-226 是选择性的，口服活性的和变构蛋白酪氨酸磷酸酶 1B 抑制剂，IC50=0.25 μM，且不激活 PPARγ 。它可以保护神经元免受脑缺血损伤。它通过增强胰岛素和瘦素信号传导发挥抗糖尿病和抗肥胖作用。
T4491	LMPTP INHIBITOR 1 hydrochloride LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))	Phosphatase	Metabolism
	LMPTP INHIBITOR 1 hydrochloride 是一种高选择性的低分子量蛋白酪氨酸磷酸酶 (LMPTP) 抑制剂。LMPTP INHIBITOR 1 (hydrochloride) 能够抑制 LMPTP-A 的活性，IC50值为 0.8 μM。
T16350	NSC-87877	Apoptosis; Phosphatase	Apoptosis; Metabolism
	NSC-87877 是一种Shp2和Shp1蛋白质酪氨酸磷酸酶抑制剂，IC50值分别为0.318 μM 和0.355 μM。它还抑制双特异性磷酸酶26。
T10927	Cyt-PTPε Inhibitor-1 Cyt-PTP\|A Inhibitor-1	Phosphatase; Src	Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
	Cyt-PTPε Inhibitor-1 (A Inhibitor-1) 是胞质蛋白酪氨酸磷酸酶 ε 的抑制剂。 Cyt-PTPε Inhibitor-1 阻断 c-Src 的去磷酸化并表现出抗破骨活性。
T7084	2-Bromo-4'-hydroxyacetophenone SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮	Phosphatase	Metabolism
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) 是一种PTP1B 的有效抑制剂，其Ki=42 μM。
T11053	DJ001	Phosphatase	Metabolism
	DJ001 是一种高度特异性，选择性和非竞争性的蛋白酪氨酸磷酸酶-σ (PTPσ) 抑制剂，IC50 为 1.43 μM。DJ001 对其他磷酸酶无抑制活性，对蛋白质磷酸酶 5 仅有中等抑制活性。DJ001 促进造血干细胞再生。
T16724	Razuprotafib AKB-9778	Phosphatase; Others	Metabolism; Others
	Razuprotafib (AKB-9778) 是一种 VE-PTP (HPTPß)催化活性的有效选择性抑制剂，抑制结构相关磷酸酶 PTP1B。除 HPTPη 和 HPTPγ 外，它对 VE-PTP 具有良好的选择性。它能够促进 TIE2 活化，增强 ANG1 诱导的 TIE2 活化，并刺激 TIE2 通路中信号分子的磷酸化。
T23132	Pentamidine dihydrochloride 喷他脒二盐酸盐,MP-601205 dihydrochloride	Phosphatase; Antibacterial; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology
	Pentamidine dihydrochloride (MP-601205 dihydrochloride) 是一种抗微生物剂，会干扰 DNA 的生物合成。它是选择性蛋白酪氨酸磷酸酶和再生肝磷酸酶抑制剂。它可用于冈比亚锥虫病，抗锑利什曼病和卡氏肺孢子虫肺炎的研究，有抗肿瘤活性，抗菌活性。
T22137	PTP Inhibitor IV	Others	Others
	PTP Inhibitor IV 是一种有效的蛋白酪氨酸磷酸酶 (PTP) 抑制剂，可选择性抑制 DUSP14 磷酸酶活性（IC50 ： 5.21 μM）。PTP Inhibitor IV 对 SHP-2、PTP1B、PTP-ε、PTP Meg-2、PTP-σ、PTP-β 和 PTP-μ具有抑制作用，IC50 分别为 1.8 μM、2.5 μM、8.4 μM、13 μM、20 μM、6.4 μM，和 6.7 μM。PTP Inhibitor IV 通过抑制PTP 活性，影响细胞信号传导，并可能调节与PTP 介导的信号传导事件相关的特定途径。
T27994	MDK-2959 PTPsigma inhibitor2,PTPsigma inhibitor 2,PTPsigmainhibitor2	Others	Others
	MDK-2959 is a potent inhibitor of protein tyrosine phosphatase sigma (PTPsigma).
T69242	NC1	Others	Others
	NC1 is a novel highly active allosteric inhibitor of protein tyrosine phosphatase, non-receptor type 22 (PTPN22) which is a lymphoid-specific tyrosine phosphatase (LYP).
T16877	SHP394	Others	Others
	SHP394 is an orally efficacious inhibitor of protein tyrosine phosphatase SHP2 (IC50: 23 nM).
T69835	Plasiatine	Others	Others
	Plasiatine is a novel potent activator of the nonreceptor protein tyrosine phosphatase shp2
T69633	TCS-401	Others	Others
	TCS-401 is an insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B).
T11730	JTT 551	Others	Others
	JTT 551 can be used in the research of type 2 diabetes mellitus. JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively.
T12116	MSI-1436 Aminosterol-1436,Trodusquemine	Others	Others
	MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)
T15166	DPM-1001	Phosphatase	Metabolism
	DPM-1001 is an orally bioavailable and non-competitive protein-tyrosine phosphatase (PTP1B) inhibitor (IC50: 100 nM) with the anti-diabetic property.
T12117	MSI-1436 lactate Trodusquemine lactate,Aminosterol-1436 lactate	Others	Others
	MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)
T27417	Glutathione arsenoxide GSAO	Others	Others
	Glutathione arsenoxide is a hydrophilic derivative of phenylarsine oxide (PAO), a protein tyrosine phosphatase inhibitor. Glutathione arsenoxide inhibits angiogenesis and tumour growth.
T70831	Glutathione maleimide	Others	Others
	Glutathione maleimide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T40745	PTP1B-IN-13 PTP1B-IN-13	Others	Others
	PTP1B-IN-13, a potent and selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B), effectively targets the allosteric site, exhibiting an IC50 value of 1.59 μM.
T68202	Glutathione diethyl ester
	Glutathione diethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T71441	Glutathione palmitamide	Others	Others
	Glutathione palmitamide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T69992	Glutathione sodium	Others	Others
	Glutathione sodium is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T70331	Glutathione sulfonate	Others	Others
	Glutathione sulfonate is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T68833	Glutathione sulfinanilide	Others	Others
	Glutathione sulfinanilide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T70602	Glutathione glycylethyl ester	Others	Others
	Glutathione glycylethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T10594	bpV(phen)	PTEN	PI3K/Akt/mTOR signaling
	bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).
T35777	Nodularin	Others	Others
	The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatotoxic monocylic pentapeptide produced by the N. spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. PP2B is inhibited to a lesser extent with an IC50 of 1.8 μM. No apparent inhibitory eff...
T40835	PTP1B-IN-14 PTP1B-IN-14	Others	Others
	PTP1B-IN-14 is a selective PTP1B inhibitor ( IC 50 = 0.72 μM) targeting the allosteric site.
T40968	MLS-0437605	Others	Others
	MLS-0437605 is a potent and selective inhibitor of dual-specificity phosphatase 3 (DUSP3), with an IC50 of 3.7 μM. It exhibits higher selectivity towards DUSP3 in comparison to DUSP22 and other protein tyrosine phosphatases (PTPs).
T63739	PTP1B-IN-15	Others	Others
	PTP1B-IN-15 是有效的、选择性的蛋白酪氨酸磷酸酶 1B (PTP1B) 抑制剂，对II 型糖尿病和肥胖症表现出研究潜力。
T41339	bpV(phen) trihydrate
	bpV(phen) trihydrate 是一种有效的蛋白酪氨酸磷酸酶 (PTP) 和 PTEN 抑制剂（对于 PTP-β、PTP-1B 和 PTEN，IC50 值：343 nM、920 nM 和 38 nM）。
T79161	PROTAC PTPN2 degrader-2 TFA	Phosphatase	Metabolism
	PROTACPTPN2 degrader-2（例187B）TFA 作为PTPN2降解剂，展现出对癌症及代谢性疾病研究的潜在效用。

化合物

Cefsulodin sodium

Cat.No: T0827

Synonym: Cefsulodine sodium,Sulcephalosporin,头孢磺啶钠

Target: Antibacterial, Antibiotic

PTP inhibitor 1

Cat.No: T7541

Synonym: PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮

Target: Phosphatase

Suramin Sodium Salt

Cat.No: T2160

Synonym: 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060

Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite

Cat.No: T12578

Synonym: PTP1B-IN-8

Target: Phosphatase

Cat.No: T4256

Target: Phosphatase

Cat.No: T7356

Synonym: PTP1B inhibitor,5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物

Target: Phosphatase

Sodium stibogluconate

Cat.No: T13013

Synonym: Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠

Target: Phosphatase

Cat.No: T31458

Synonym: 6,8-Difluoro-4-methylumbelliferyl phosphate

Cat.No: T7381

Target: Phosphatase

Cat.No: T13176

Synonym: Batoprotafib

Target: Phosphatase

Cat.No: T14841

Target: Phosphatase, P450, Histone Methyltransferase

Cat.No: T67893

Target: Phosphatase

Cat.No: T37184

Synonym: 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid

Target: Phosphatase

Cat.No: T10190

Target: Phosphatase

LMPTP INHIBITOR 1 dihydrochloride

Cat.No: T41298

Target: Phosphatase

Cat.No: T61678

Target: Phosphatase

Cat.No: T7704

Target: Phosphatase

LMPTP INHIBITOR 1 hydrochloride

Cat.No: T4491

Synonym: LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))

Target: Phosphatase

Cat.No: T16350

Target: Apoptosis, Phosphatase

Cyt-PTPε Inhibitor-1

Cat.No: T10927

Synonym: Cyt-PTP|A Inhibitor-1

Target: Phosphatase, Src

2-Bromo-4'-hydroxyacetophenone

Cat.No: T7084

Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮

Target: Phosphatase

Cat.No: T11053

Target: Phosphatase

Cat.No: T16724

Synonym: AKB-9778

Target: Phosphatase, Others

Pentamidine dihydrochloride

Cat.No: T23132

Synonym: 喷他脒二盐酸盐,MP-601205 dihydrochloride

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

PTP Inhibitor IV

Cat.No: T22137

Target: Others

Cat.No: T27994

Synonym: PTPsigma inhibitor2,PTPsigma inhibitor 2,PTPsigmainhibitor2

Target: Others

Cat.No: T69242

Target: Others

Cat.No: T16877

Target: Others

Cat.No: T69835

Target: Others

Cat.No: T69633

Target: Others

Cat.No: T11730

Target: Others

Cat.No: T12116

Synonym: Aminosterol-1436,Trodusquemine

Target: Others

Cat.No: T15166

Target: Phosphatase

MSI-1436 lactate

Cat.No: T12117

Synonym: Trodusquemine lactate,Aminosterol-1436 lactate

Target: Others

Glutathione arsenoxide

Cat.No: T27417

Synonym: GSAO

Target: Others

Glutathione maleimide

Cat.No: T70831

Target: Others

Cat.No: T40745

Synonym: PTP1B-IN-13

Target: Others

Glutathione diethyl ester

Cat.No: T68202

Glutathione palmitamide

Cat.No: T71441

Target: Others

Glutathione sodium

Cat.No: T69992

Target: Others

Glutathione sulfonate

Cat.No: T70331

Target: Others

Glutathione sulfinanilide

Cat.No: T68833

Target: Others

Glutathione glycylethyl ester

Cat.No: T70602

Target: Others

Cat.No: T10594

Target: PTEN

Cat.No: T35777

Target: Others

Cat.No: T40835

Synonym: PTP1B-IN-14

Target: Others

Cat.No: T40968

Target: Others

Cat.No: T63739

Target: Others

bpV(phen) trihydrate

Cat.No: T41339

PROTAC PTPN2 degrader-2 TFA

Cat.No: T79161

Target: Phosphatase

Cat. No.	Product Name	Target	Signaling Pathways
TN1053	Aloe-emodin-8-O-β-D-glucopyranoside Aloe-emodin-8-O-beta-D-glucopyranoside,芦荟大黄素-8-O-β-D-葡萄糖苷	Phosphatase	Metabolism
	Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) 是一种分离自Saussrurea lappa 中的化合物，是一种温和的人类蛋白酪氨酸磷酸酶 1B 抑制剂，其IC50=26.6 μM。
TN1470	Cassiaside B2 决明子苷B2	Phosphatase; MAO; 5-HT Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Cassiaside B2 是蛋白酪氨酸磷酸酶1B (PTP1B) 和人单胺氧化酶A (hMAO-A) 的抑制剂。Cassiaside B2是 5-HT2C 受体的激动剂，具有抗过敏活性。Cassiaside B2 是萘吡喃酮参比提取物（NRE）的有效成分之一。
TN2111	Prunin Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷	Phosphatase; Anti-infection; Virus Protease	Metabolism; Microbiology/Virology
	Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B，IC50值为 5.5 μM。
T3S1612	kuwanon G 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G	Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂，具有杀菌作用。
TN5400	Aerugidiol
	Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B).
T19885	Methyllucidone
	Methyllucidone is an inhibitor of STAT3 that acts by regulating the expression of the protein tyrosine phosphatase MEG2.
T39219	Ficusonolide	Others	Others
	Ficusonolide exhibits significant antidiabetic activity through its interactions with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.
TN3335	Abyssinone V	Phosphatase	Metabolism
	Abyssinone V 是一种从刺桐茎皮中分离的天然化合物，是蛋白质酪氨酸磷酸酶 1B (PTP1B) 的抑制剂。
T13740	Isotanshinone IIA	Others	Others
	Isotanshinone IIA, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. is an abietane-type diterpene metabolite.
TN2887	3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid	Phosphatase	Metabolism
	(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM.
T73073	PTP1B-IN-21	Others	Others
	PTP1B-IN-21 是蛋白酪氨酸磷酸酶 1B (PTP1B) 的选择性抑制剂 (IC50=1.56 μM)，抑制力超出高度同源 T 细胞蛋白酪氨酸磷酸酶 (TCPTP；IC50>100 μM)，PTP1B 是抑制 2 型糖尿病的重要靶点。
TN2913	3-Acetoxy-11-ursen-28,13-olide	Phosphatase	Metabolism
	3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line.
TN3505	Beta-Peltoboykinolic acid	Phosphatase	Metabolism
	Beta-Peltoboykinolic acid has in vitro protein tyrosine phosphatase 1B (PTP1B) inhibitory, it inhibits PTP1B with IC50 values of 5.2+/-0.5 microM. It also has cytotoxic activity.
T73072	PTP1B-IN-20	Others	Others
	PTP1B-IN-20 是蛋白酪氨酸磷酸酶 1B (PTP1B) 的选择性抑制剂 (IC50=1.05 μM)，抑制力超出高度同源 T 细胞蛋白酪氨酸磷酸酶 (TCPTP；IC50=78.0 μM)，PTP1B 是抑制 2 型糖尿病的重要靶点。
TN1775	Isocryptotanshinone	ERK; JNK; STAT	JAK/STAT signaling; MAPK; Stem Cells
	Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.
T3827	Rhein-8-glucoside calcium 大黄酸-8-O-β-D-葡萄糖苷,Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt	Phosphatase; Antibacterial	Metabolism; Microbiology/Virology
	Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt 是一种从 Saussurea lappa 根的 EtOH 提取物中，分离得到的蒽醌类 hPTP1B 抑制剂，IC50值为11.5 μM，具有抗菌作用。
TN3525	Boehmenan	ERK; Phosphatase; EGFR; PARP; MEK; Wnt/beta-catenin; Akt; Caspase; STAT; p53	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell
T38069	Aquastatin A	Others	Others
	Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K....
T75495	Rubrofusarin 6-O-β-D-glucopyranoside	Others	Others
	Rubrofusarin 6-O-β-D-glucopyranoside为Rubrofusarin的糖苷形式，具有抑制蛋白酪氨酸磷酸酶 1B (PTP1B) 的活性，IC50值为87.36 μM，适用于糖尿病和抑郁症研究。
TN4279	Isoderrone	Tyrosinase	Proteases/Proteasome
	Isoderrone 在体外对α-葡萄糖苷酶(α-glucosidase)有抑制作用；它是一种蛋白酪氨酸磷酸酶1B（PTP1B）抑制剂，IC50值为22.7±1.7μM，表明它可能是一种治疗2型糖尿病的新药。
T79985	Cryptosporioptide A	Phosphatase	Metabolism
	Cryptosporioptide A (Compound 3)是一种从昆虫寄生真菌Cordyceps gracilioides中分离出的色素蛋白酪氨酸磷酸酶抑制剂，针对PTP1B、SHP2、CDC25B、LAR和SHP1等酶展示了抑制作用，其IC50值分别为7.3、5.7、7.6、>50、4.9 μg/mL。
TN2928	Pygenic acid A 3-Epicorosolic acid,脓毒酸A
	3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.3-Epicorosolic acid shows both potent α-glucosidase and pro
T80007	Stevisalioside A	Phosphatase	Metabolism
	Stevisalioside A (Compound 2)，一种从甜叶菊根提取的化合物，展现出抗糖尿病的口服活性。该化合物有效抑制PTP1B，IC50为526.8 μM，并能降低Stevisalioside A引起的高血糖小鼠血糖水平，改善餐后血糖峰值及口服葡萄糖和胰岛素耐量测试结果。

天然产物

Aloe-emodin-8-O-β-D-glucopyranoside

Cat.No: TN1053

Synonym: Aloe-emodin-8-O-beta-D-glucopyranoside,芦荟大黄素-8-O-β-D-葡萄糖苷

Target: Phosphatase

Cat.No: TN1470

Synonym: 决明子苷B2

Target: Phosphatase, MAO, 5-HT Receptor

Cat.No: TN2111

Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Target: Phosphatase, Anti-infection, Virus Protease

Cat.No: T3S1612

Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Cat.No: TN5400

Cat.No: T19885

Cat.No: T39219

Target: Others

Cat.No: TN3335

Target: Phosphatase

Isotanshinone IIA

Cat.No: T13740

Target: Others

3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid

Cat.No: TN2887

Target: Phosphatase

Cat.No: T73073

Target: Others

3-Acetoxy-11-ursen-28,13-olide

Cat.No: TN2913

Target: Phosphatase

Beta-Peltoboykinolic acid

Cat.No: TN3505

Target: Phosphatase

Cat.No: T73072

Target: Others

Isocryptotanshinone

Cat.No: TN1775

Target: ERK, JNK, STAT

Rhein-8-glucoside calcium

Cat.No: T3827

Synonym: 大黄酸-8-O-β-D-葡萄糖苷,Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt

Target: Phosphatase, Antibacterial

Cat.No: TN3525

Target: ERK, Phosphatase, EGFR, PARP, MEK, Wnt/beta-catenin, Akt, Caspase, STAT, p53

Cat.No: T38069

Target: Others

Rubrofusarin 6-O-β-D-glucopyranoside

Cat.No: T75495

Target: Others

Cat.No: TN4279

Target: Tyrosinase

Cryptosporioptide A

Cat.No: T79985

Target: Phosphatase

Cat.No: TN2928

Synonym: 3-Epicorosolic acid,脓毒酸A

Stevisalioside A

Cat.No: T80007

Target: Phosphatase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04125	PTP1B Protein, Human, Recombinant (His) protein tyrosine phosphatase, non...	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein p...
TMPY-03548	PTPN12 Protein, Human, Recombinant protein tyrosine phosphatase, non...	Human	Baculovirus Insect Cells
	PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.
TMPY-03484	TCPTP Protein, Human, Recombinant TCPTP,protein tyrosine phosphatase	Human	Baculovirus Insect Cells
	TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosp...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His) L-CA,T200,LCA,B220,protein tyrosine ph...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPJ-00465	PTP1C Protein, Human, Recombinant (His) HCP,Hematopoietic Cell Protein-Tyrosine	Human	E. coli
	Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPH-02278	PTPN5 Protein, Human, Recombinant (His & SUMO) PTPN5,Neural-specific protein-tyrosine	Human	E. coli
	May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. PTPN5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.5 kDa and the accession number is P54829.
TMPH-02277	PTPN11 Protein, Human, Recombinant (T253M & Q257L, His) Protein-tyrosine phosphatase 1D,<...	Human	E. coli
	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity. Dephosphorylates CDC73. Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification.
TMPH-02011	PTPRB Protein, Human, Recombinant (His & SUMO) PTPRB,Receptor-type tyrosine-protein p...	Human	E. coli
	PTPRB Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02010	PTPRB Protein, Human, Recombinant (His) Vascular endothelial protein tyrosine ...	Human	P. pastoris (Yeast)
	PTPRB Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-02878	PTPRS Protein, Mouse, Recombinant (His & Myc) Receptor-type tyrosine-protein phospha...	Mouse	E. coli
	Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteo...
TMPH-02013	PTPRZ1 Protein, Human, Recombinant (His) Protein-tyrosine phosphatase rece...	Human	P. pastoris (Yeast)
	Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades. PTPRZ1 Protein, Human, Recombinant (His) is exp...
TMPH-02987	PTPRS Protein, Mus musculus, Recombinant (His & Myc) Ptprs,Receptor-type tyrosine-protein p...	Mouse	Baculovirus Insect Cells
	PTPRS Protein, Mus musculus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 35.8 kDa and the accession number is B0V2N1.
TMPH-02012	PTPRZ1 Protein, Human, Recombinant (E. coli, His) Protein-tyrosine phosphatase rece...	Human	E. coli
	PTPRZ1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPJ-00053	PRL-2 Protein, Human, Recombinant (His) HU-PP-1,Protein tyrosine phosphatase	Human	E. coli
	PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeran...
TMPH-03719	YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc) yopH,Virulence protein,Tyrosine-protei...	Yersinia enterocolitica	E. coli
	Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.
TMPJ-00808	CD45RA Protein, Human, Recombinant (His) PTPRC,CD45R,CD45,LCA,protein tyrosine ...	Human	HEK293 Cells
	CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPJ-00794	CD45 Protein, Mouse, Recombinant (His) CD45,receptor-type tyrosine-protein ph...	Mouse	HEK293 Cells
	CD45 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 120-160 KDa and the accession number is P06800.
TMPY-00487	PTPN9 Protein, Human, Recombinant (His & GST) PTPMEG2,protein tyrosine phosphatase	Human	Baculovirus Insect Cells
	Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 and ZBP-89, providing new cellular and molecular insights into the role of ptpn9a in developmental hematopoiesis.
TMPJ-00410	CD45R0 Protein, Human, Recombinant (His) CD45 antigen,L-CA,protein tyrosine pho...	Human	HEK293 Cells
	CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPY-02369	TCPTP Protein, Mouse, Recombinant (aa 2-314, His) protein tyrosine phosphatase, non...	Mouse	Baculovirus Insect Cells
	TCPTP Protein, Mouse, Recombinant (aa 2-314, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 38.7 kDa and the accession number is Q06180-1.
TMPY-02173	TCPTP Protein, Human, Recombinant (aa 1-314, His & GST) TCPTP,TC-PTP,protein tyrosine phosphat...	Human	Baculovirus Insect Cells
	TCPTP Protein, Human, Recombinant (aa 1-314, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 64.4 kDa and the accession number is P17706-1.
TMPY-03486	PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) PTPG1,protein tyrosine phosphatase	Human	Baculovirus Insect Cells
	PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.4 kDa and the accession number is AAA36529.1.
TMPY-02602	PTPMT1 Protein, Human, Recombinant (His) protein tyrosine phosphatase, mit...	Human	E. coli
	PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion. It has been recently reported that PTPMT1 dephosphorylates phosphatidylglycerol phosphate, an essential intermediate of cardiolipin biosynthesis. PTPMT1 deficiency in mouse embryonic fibroblasts compromises mitochondrial respiration and results in abnormal mitochondrial morphology. Lipid analysis of PTPMT1-deficient fibroblasts reveals an a...
TMPY-02763	DEP-1 Protein, Human, Recombinant (aa 997-1337, His) HPTPeta,SCC1,protein tyrosine phosphat...	Human	E. coli
	DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. DEP1 / PTPRJ possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-...
TMPY-04277	CD45 Protein, Mouse, Recombinant (hFc) Cd45,protein tyrosine phosphatase...	Mouse	HEK293 Cells
	CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-03270	CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) Ly-5,CD45R,Lyt-4,T200,loc,protein tyrosine...	Mouse	Baculovirus Insect Cells
	CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 108.2 kDa and the accession number is AAA39458.1.
TMPY-03468	CD45 Protein, Mouse, Recombinant (aa 453-1152) loc,Lyt-4,protein tyrosine phosphatase...	Mouse	Baculovirus Insect Cells
	CD45 Protein, Mouse, Recombinant (aa 453-1152) is expressed in Baculovirus insect cells. The predicted molecular weight is 81 kDa and the accession number is AAA39458.1.
TMPY-03296	SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) SH-PTP1,Hcph,70Z-SHP,Ptp1C,protein tyrosine	Mouse	Baculovirus Insect Cells
	PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of PTPN6 contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of PTPN6 with its substrates. PTPN6 is expressed primarily in hematopoietic cells, and functions as an ...
TMPY-02511	PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST) LRP,PTP α/PTPRA Protein, Human, Recombinant (aa 174...	Human	Baculovirus Insect Cells
	PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTPRA could promote the cell cycle progression through stimulating the c-Src signaling pathways. The PTPRA gene, which encodes the protein RPTP-alpha, is critical to neurodevelopment. Previous linkage studies, genome-wide association studies, controlled expression analyses and anima...
TMPY-00711	CD45 Protein, Human, Recombinant (hFc) GP180,L-CA,LY5,T200,protein tyrosine p...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4.
TMPJ-01139	IA2 Protein, Human, Recombinant (aa 576-950, His) Islet cell antigen 512,Islet cell autoantigen 3,ICA3,Recepto...	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 576-950, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50 KDa and the accession number is Q16849.
TMPJ-01140	IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His) Islet cell autoantigen 3,PTPRN,Islet cell antigen 512,ICA3,I...	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26-30 KDa and the accession number is Q16849.
TMPJ-01141	IA2 Protein, Human, Recombinant (aa 687-979, His) PTP IA-2,PTPRN,ICA3,R-PTP-N,ICA 512,Islet cell antigen 512,I...	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 687-979, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is Q16849.
TMPJ-01181	SIRP alpha Protein, Mouse, Recombinant (aa 32-373, hFc) SIRPA,SHPS1,Tyrosine-Protein Phosphata...	Mouse	HEK293 Cells
	SIRP alpha Protein, Mouse, Recombinant (aa 32-373, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 115-125 KDa and the accession number is Q6P6I8.
TMPJ-01182	SIRP alpha Protein, Mouse, Recombinant (MIgG2a) SIRP,CD172 Antigen-Like Family Member A,SIRPA,MFR,Signal-Reg...	Mouse	HEK293 Cells
	SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bovine, and porcine SIRP alpha, respectively.SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-l...
TMPY-03125	SHP-2 Protein, Mouse, Recombinant (His) SAP-2,Syp,PTP1D,SH-PTP2,SH-PTP3,SHP-2,PTP2C,2700084A17Rik,AW...	Mouse	HEK293 Cells
	SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric acid monoesters. They dephosphorylate EGFR, JAK2 and TYK2 kinases, promoting oncogenic transformation. SHP2 is widely expressed, with highest levels in heart, brain, and skeletal muscle. SHP2 acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participat...
TMPY-02386	PTP4A2 Protein, Human, Recombinant (GST) HNMT-S2,PRL-2,HNMT-S1,protein tyrosine	Human	E. coli
	PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeu...
TMPJ-01183	SIRP alpha Protein, Mouse, Recombinant (aa 32-373, His) CD172 Antigen-Like Family Member A,Macrophage Fusion Recepto...	Mouse	HEK293 Cells
	SIRP alpha Protein, Mouse, Recombinant (aa 32-373, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 60-110 KDa and the accession number is Q6P6I8.
TMPJ-00306	SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated Brain Ig-Like Molecule with Tyrosine-Based Activati...	Human	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ...
TMPJ-00305	SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His) Inhibitory Feceptor SHPS-1,MyD-1 Antig,Brain Ig-Like Molecul...	Cynomolgus	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ...
TMPJ-00908	LMW-PTP Protein, Human, Recombinant (His) Low Molecular Weight Cytosolic Acid Phosphatase,Adi...	Human	E. coli
	Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphatase (PTPase) by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. LMW-PTP can be detected in all human tissues, including adipocytes. LMW-PTP is a cytosolic enzyme that regulate cell proliferation and growth of leiomyomas during dephosphorylation of t...
TMPJ-01205	MDP1 Protein, Human, Recombinant (His) Magnesium-dependent phosphatase 1,MDP-1,EC=3.1.3.48	Human	HEK293 Cells
	MDP1, which is short for nesium-dependent phosphatase 1, is a 176 aa. protein. It has 3 forms by different alternative splicing. This protein belongs to the HAD-like hydrolase superfamily, and usually takes its function with Magnesium. It can be inhibited by vanadate and zinc, and slightly by calcium. MDP1 is a Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
TMPH-03161	Alkaline Phosphatase Protein, Prevotella intermedia, Recombinant (GST & His & Myc) PiALP,ALPase	Prevotella intermedia	E. coli
	Acts against tyrosine-phosphatases. Alkaline Phosphatase Protein, Prevotella intermedia, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 32.1 kDa and the accession number is P81800.
TMPJ-00223	SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated CDw150,CD150,SLAM,IPO-3,SLAMF1,Signaling Lymphocytic Activat...	Human	HEK293 Cells
	SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
TMPH-01703	CDC25C Protein, Human, Recombinant (His) Dual specificity phosphatase Cdc25C,M-phase inducer...	Human	E. coli
	Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity. CDC25C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 57.4 kDa and the accession number is P30307.
TMPY-03440	Sts1 Protein, Human, Recombinant (His) STS-1,ubiquitin associated and SH3 domain containing B,p70,S...	Human	E. coli
	UBASH3B contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. UBASH3B was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. UBASH3B interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. It promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on...
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP) MKP6,MKP-L,dual specificity phosphatase 14	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosphotyrosine and phosphoserine / phosphothreonine residues in substrates. Unlike many other DUSPs, DUSP14 only contains a catalytic domain within the C-terminal region. In signal transduction, DUSP14 has been considered as negative regulator of the mitogen-activated protein kinase (...
TMPY-02002	PHPT1 Protein, Human, Recombinant (His) phosphohistidine phosphatase 1,CGI-202,HSPC141,HEL-...	Human	E. coli
	PHPT1, also known as 14 kDa phosphohistidine phosphatase, phosphohistidine phosphatase 1, protein janus-A homolog, PHP14, is a cytoplasm protein which belongs to the janus family. PHPT1 / PHP14 is expressed abundantly in heart and skeletal muscle. Phosphatases are a diverse group of enzymes that regulate numerous cellular processes. Much of what is known relates to the tyrosine, threonine, and serine phosphatases, whereas the histidine phosphatases have not been studied as much. Protein histidin...
TMPJ-00226	SLAMF1 Protein, Mouse, Recombinant (His) signaling lymphocytic activation molecule,SLAM family member...	Mouse	HEK293 Cells
	Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been...
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重组蛋白

PTP1B Protein, Human, Recombinant (His)

Cat.No: TMPY-04125

Species: Human

Expression System: E. coli

PTPN12 Protein, Human, Recombinant

Cat.No: TMPY-03548

Species: Human

Expression System: Baculovirus Insect Cells

TCPTP Protein, Human, Recombinant

Cat.No: TMPY-03484

Species: Human

Expression System: Baculovirus Insect Cells

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 26-577, His)

Cat.No: TMPY-05748

Species: Human

Expression System: HEK293 Cells

PTP1C Protein, Human, Recombinant (His)

Cat.No: TMPJ-00465

Species: Human

Expression System: E. coli

PTPN5 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02278

Species: Human

Expression System: E. coli

PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)

Cat.No: TMPH-02277

Species: Human

Expression System: E. coli

PTPRB Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02011

Species: Human

Expression System: E. coli

PTPRB Protein, Human, Recombinant (His)

Cat.No: TMPH-02010

Species: Human

Expression System: P. pastoris (Yeast)

PTPRS Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02878

Species: Mouse

Expression System: E. coli

PTPRZ1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02013

Species: Human

Expression System: P. pastoris (Yeast)

PTPRS Protein, Mus musculus, Recombinant (His & Myc)

Cat.No: TMPH-02987

Species: Mouse

Expression System: Baculovirus Insect Cells

PTPRZ1 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02012

Species: Human

Expression System: E. coli

PRL-2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00053

Species: Human

Expression System: E. coli

YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)

Cat.No: TMPH-03719

Species: Yersinia enterocolitica

Expression System: E. coli

CD45RA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00808

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00794

Species: Mouse

Expression System: HEK293 Cells

PTPN9 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-00487

Species: Human

Expression System: Baculovirus Insect Cells

CD45R0 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00410

Species: Human

Expression System: HEK293 Cells

TCPTP Protein, Mouse, Recombinant (aa 2-314, His)

Cat.No: TMPY-02369

Species: Mouse

Expression System: Baculovirus Insect Cells

TCPTP Protein, Human, Recombinant (aa 1-314, His & GST)

Cat.No: TMPY-02173

Species: Human

Expression System: Baculovirus Insect Cells

PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST)

Cat.No: TMPY-03486

Species: Human

Expression System: Baculovirus Insect Cells

PTPMT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02602

Species: Human

Expression System: E. coli

DEP-1 Protein, Human, Recombinant (aa 997-1337, His)

Cat.No: TMPY-02763

Species: Human

Expression System: E. coli

CD45 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04277

Species: Mouse

Expression System: HEK293 Cells

CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST)

Cat.No: TMPY-03270

Species: Mouse

Expression System: Baculovirus Insect Cells

CD45 Protein, Mouse, Recombinant (aa 453-1152)

Cat.No: TMPY-03468

Species: Mouse

Expression System: Baculovirus Insect Cells

SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)

Cat.No: TMPY-03296

Species: Mouse

Expression System: Baculovirus Insect Cells

PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)

Cat.No: TMPY-02511

Species: Human

Expression System: Baculovirus Insect Cells

CD45 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00711

Species: Human

Expression System: HEK293 Cells

IA2 Protein, Human, Recombinant (aa 576-950, His)

Cat.No: TMPJ-01139

Species: Human

Expression System: E. coli

IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His)

Cat.No: TMPJ-01140

Species: Human

Expression System: E. coli

IA2 Protein, Human, Recombinant (aa 687-979, His)

Cat.No: TMPJ-01141

Species: Human

Expression System: E. coli

SIRP alpha Protein, Mouse, Recombinant (aa 32-373, hFc)

Cat.No: TMPJ-01181

Species: Mouse

Expression System: HEK293 Cells

SIRP alpha Protein, Mouse, Recombinant (MIgG2a)

Cat.No: TMPJ-01182

Species: Mouse

Expression System: HEK293 Cells

SHP-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03125

Species: Mouse

Expression System: HEK293 Cells

PTP4A2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02386

Species: Human

Expression System: E. coli

SIRP alpha Protein, Mouse, Recombinant (aa 32-373, His)

Cat.No: TMPJ-01183

Species: Mouse

Expression System: HEK293 Cells

SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00306

Species: Human

Expression System: HEK293 Cells

SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)

Cat.No: TMPJ-00305

Species: Cynomolgus

Expression System: HEK293 Cells

LMW-PTP Protein, Human, Recombinant (His)

Cat.No: TMPJ-00908

Species: Human

Expression System: E. coli

MDP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01205

Species: Human

Expression System: HEK293 Cells

Alkaline Phosphatase Protein, Prevotella intermedia, Recombinant (GST & His & Myc)

Cat.No: TMPH-03161

Species: Prevotella intermedia

Expression System: E. coli

SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00223

Species: Human

Expression System: HEK293 Cells

CDC25C Protein, Human, Recombinant (His)

Cat.No: TMPH-01703

Species: Human

Expression System: E. coli

Sts1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03440

Species: Human

Expression System: E. coli

DUSP14 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPY-02595

Species: Human

Expression System: E. coli

PHPT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02002

Species: Human

Expression System: E. coli

SLAMF1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00226

Species: Mouse

Expression System: HEK293 Cells

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