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Targets Recommended: Others

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Cat. No.	Product Name	Target	Signaling Pathways
T85251	1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE 16:0 Dimethyl PE,1,2-N,NMe2DPPE,1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-Phosphoethanolamine	Others	Others
	1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.
T85089	1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE 16:0-d9/16:0-PE,PE(16:0-d9/16:0),1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine,1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylethanolamine	Others	Others
	1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE serves as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) using GC- or LC-MS. 1,2-DPPE, a prevalent PE (phospholipid), contains C16:0 fatty acids at the sn-1 and sn-2 positions and is essential in the inner plasma membrane leaflet. This compound forms a condensed lipid monolayer with cholesterol through tight hydrogen bonding between 1,2-DPPE headgroups, enhancing membrane fluidity to support transport and signa...
T36138	BMP-22	Others	Others
	BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM). It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 (0.1-1,000 nM) inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine in vitro in a concentration-dependent manner. It inhibits LPC-dependent MM1 cell invasion of a human umbilical vein endothelial cell (HUVEC) monolayer. BMP-22 (0.5 mg/kg per day) decreases the number of lung metastatic foci in a B16/F10 syngene...
T69888	SB02024	Others	Others
	SB02024 is a VPS34 inhibitor. SB02024 activates cGAS-STING signaling and sensitizes tumors to STING agonist. SB02024 blocked autophagy in vitro and reduced xenograft growth of two breast cancer cell lines, MDA-MB-231 and MCF-7, in vivo. Vps34 inhibitor significantly potentiated cytotoxicity of Sunitinib and Erlotinib in MCF-7 and MDA-MB-231 in vitro in monolayer cultures and when grown as multicellular spheroids. Our data suggests that inhibition of autophagy significantly improves sensitivity...
T80191	His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA	Endogenous Metabolite	Metabolism
	His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA，GHRP-1的一种代谢产物，属于生长激素释放肽类。作为Ala-His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2的同义物，GHRP-1能够刺激GH（生长激素）的释放。在大鼠垂体静态单层细胞试验中，GHRP-1可提高GH释放率和[Ca2+]i水平，但对cAMP浓度无显著影响。

化合物

1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE

Cat.No: T85251

Synonym: 16:0 Dimethyl PE,1,2-N,NMe2DPPE,1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-Phosphoethanolamine

Target: Others

1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE

Cat.No: T85089

Synonym: 16:0-d9/16:0-PE,PE(16:0-d9/16:0),1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine,1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylethanolamine

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA

Cat.No: T80191

Synonym:

Target: Endogenous Metabolite

Cat. No.	Product Name	Target	Signaling Pathways
T21437	DSPS DSPS (From soybeans),Phosphatidylserine(36:0),磷脂酰丝氨酸,Dioctadecanoylphosphatidylserine,Distearoyl phosphatidylserine	Others	Others
	DSPS (Dioctadecanoylphosphatidylserine) 是一种甘油磷脂，是重要的磷脂膜成分，在细胞周期信号传导中起关键作用。DSPS 可以调节细胞活性，介导细胞凋亡。DSPS 被广泛用作营养补充剂。
TN1386	Angelol A 当归酚A,当归醇A	Others	Others
	Angelol A and angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
TN1387	Angelol B	Others	Others
	The absorption and transport of angelol A and Angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
TN3070	4beta-Hydroxywithanolide E	PARP; HSP; NF-κB; COX	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by mo

天然产物

DSPS

Cat.No: T21437

Synonym: DSPS (From soybeans),Phosphatidylserine(36:0),磷脂酰丝氨酸,Dioctadecanoylphosphatidylserine,Distearoyl phosphatidylserine

Target: Others

Angelol A

Cat.No: TN1386

Synonym: 当归酚A,当归醇A

4beta-Hydroxywithanolide E

Cat.No: TN3070

Synonym:

Target: PARP, HSP, NF-κB, COX

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02187	Tenascin Protein, Human, Recombinant (E. coli, His) GMEM,Glioma-associated-extracellular matrix antigen,Neuronec...	Human	E. coli
	Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells.

重组蛋白

Tenascin Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02187

Species: Human

Expression System: E. coli

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