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Search Results for " trehalose "

7

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T36081	Trehalose 6-phosphate (potassium salt hydrate)	Others	Others
	Trehalose is a natural non-reducing disaccharide found in plants, invertebrates, fungi, and bacteria.1,2In addition to roles as an energy source and stress protectant, trehalose can function as a signaling molecule.3,4Trehalose 6-phosphate is an intermediate in the biosynthesis of trehalose. It is generated from UDP-glucose and glucose 6-phosphate by trehalose 6-phosphate synthase (TPS or otsA).5In plants, changes in trehalose 6-phosphate levels positively correlate with diurnal changes in sucro...
T19590	Trehalose 6-behenate	Others	Others
	Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.
T82140	Hypertrehalosemic neuropeptide (Nauphoeta cinerea)
	Hypertrehalosemic neuropeptide (Nauphoeta cinerea) 属于脂动激素/红色素浓缩激素 (AKH/RPCH) 家族，具有促进海藻糖合成的功能。
T124605	Neotrehalose	Others	Others
	Neotrehalose 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124605，CAS号为 585-91-1。
T76896	Abrezekimab UCB4144,VR 942	IL Receptor	Immunology/Inflammation
	Abrezekimab (VR 942) 由 CDP7766、亮氨酸和海藻糖组成。Abrezekimab 是一种人源化靶向人 IL-13 的抗体。Abrezekimab 制止与 IL-13Rα1 亚基的结合。Abrezekimab 可用于研究哮喘和肺部疾病相关的生物障碍。
T25846	N-Acylkansosamine	Others	Others
	N-Acylkansosamine is a N-acylamino sugar isolated from trehalose-containing lipopolysaccharide antigens of Mycobacterium kansasii.
T36357	Dimethyldioctadecylammonium (bromide)	Others	Others
	Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic...

化合物

Trehalose 6-phosphate (potassium salt hydrate)

Cat.No: T36081

Target: Others

Trehalose 6-behenate

Cat.No: T19590

Target: Others

Hypertrehalosemic neuropeptide (Nauphoeta cinerea)

Cat.No: T82140

Cat.No: T124605

Target: Others

Cat.No: T76896

Synonym: UCB4144,VR 942

Target: IL Receptor

N-Acylkansosamine

Cat.No: T25846

Target: Others

Dimethyldioctadecylammonium (bromide)

Cat.No: T36357

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2O2798	D-(+)-Trehalose Ergot Sugar,D-Trehalose,Mycose,D-(+)-Trehalose Anhydrous,D-海藻糖,Trehalose	Others; Endogenous Metabolite	Metabolism; Others
	D-(+)-Trehalose (Mycose) 来源于自Saccharomyces cerevisiae，常用作食品成分和药物赋形剂。
T3145	D-(+)-Trehalose dihydrate Trehalose dihydrate,α,α-Trehalose dihydrate,alpha,alpha-Trehalose dihydrate,D-Trehalose dihydrate,二水合海藻糖	Others	Others
	D-(+)-Trehalose dihydrate (α,α-Trehalose dihydrate) 是分离自 Saccharomyces cerevisiae 中，可用作食品成分和药物赋形剂。
T78471	α,α-Trehalose 6-phosphate potassium Tre6P potassium	Endogenous Metabolite	Metabolism
	α,α-Trehalose 6-phosphate (Tre6P) potassium 是一种α,α′-trehalose的6-磷酸衍生物及内源代谢物。在Tre6P磷酸酶 (T6PP) 的催化下，α,α-Trehalose 6-phosphate可被高效转化为α,α′-trehalose。
T80698	β,β-Trehalose
	β,β-Trehalose为海藻糖类似物，能够促进菟丝子茎尖生长，并可由非特异性β-葡萄糖苷酶进行裂解。
TN7284	Lentztrehalose B	Others	Others
	Lentztrehalose B, a microbial disaccharide metabolite isolated from Lentzea, exhibits a range of biological activities. At a concentration of 100 µM, it demonstrates antioxidant properties in an oxygen radical absorbance capacity (ORAC) assay. Furthermore, Lentztrehalose B at 10 mM inhibits porcine kidney trehalase, an enzyme involved in trehalose metabolism. Additionally, it induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells when applied at 100 mM.
TN7283	Lentztrehalose A (+)-Lentztrehalose A	Others	Others
	Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase—an enzyme involved in trehalose metabolism—more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and >20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enh...
T83762	Lentztrehalose C	Others	Others
	Lentztrehalose C，一种在Lentzea中发现的二糖，具有诱导自噬活性。在100 mM浓度下，它能诱导MeWo黑色素瘤细胞和OVK18卵巢癌细胞进行自噬。
T38268	Validamycin A	Others	Others
	Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM; IC50 = 0.7 μM). It is also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi. This compound has also been used to study trehalase activity and trehalose biosynthesis.

天然产物

D-(+)-Trehalose

Cat.No: T2O2798

Synonym: Ergot Sugar,D-Trehalose,Mycose,D-(+)-Trehalose Anhydrous,D-海藻糖,Trehalose

Target: Others, Endogenous Metabolite

D-(+)-Trehalose dihydrate

Cat.No: T3145

Synonym: Trehalose dihydrate,α,α-Trehalose dihydrate,alpha,alpha-Trehalose dihydrate,D-Trehalose dihydrate,二水合海藻糖

Target: Others

α,α-Trehalose 6-phosphate potassium

Cat.No: T78471

Synonym: Tre6P potassium

Target: Endogenous Metabolite

β,β-Trehalose

Cat.No: T80698

Lentztrehalose B

Cat.No: TN7284

Target: Others

Lentztrehalose A

Cat.No: TN7283

Synonym: (+)-Lentztrehalose A

Target: Others

Lentztrehalose C

Cat.No: T83762

Target: Others

Cat.No: T38268

Target: Others

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