Deuterium Labeled Compounds

氘（氢-2）标记化合物是其中一个或多个氢原子被氘（氢的稳定同位素）取代的化合物。氘的原子核中有一个质子和一个中子，而最常见的氢同位素（氕）只有一个质子。氘（氢-2）标记化合物可用于研究药物代谢和反应动力学。

Cat. No.	Product Name	CAS No.	Purity
T12221	Nicardipine-d3 hydrochloride 盐酸尼卡地平 D3	1432061-50-1	98%
T12221	Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.
T19449	N-desmethyl Enzalutamide D6 化合物 T19449		98%
T19449	N-desmethyl Enzalutamide D6 is a deuterium labeled N-desmethyl Enzalutamide.
T71328	Theobromine-d6 化合物 Theobromine-d6	117490-40-1	98%
T71328	Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and de...
T10681	Cariprazine D6 化合物 T10681	1308278-67-2	98%
T10681	Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
T71401	Oxaliplatin-d10 化合物 Oxaliplatin-d10	1132819-16-9	98%
T71401	Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-cross...
T69673	Deucrictibant 化合物 Deucrictibant	2340111-58-0	98%
T69673	Deucrictibant is a bradykinin receptor antagonist.
T71302	Norfluoxetine-d5 HCl 化合物 Norfluoxetine-d5 HCl	1185132-92-6	98%
T71302	Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of th...
T10350	Apremilast-d5 化合物 T10350	1258597-47-5	98%
T10350	Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-α rele...
T12291	Olanzapine D3 化合物 T12291	786686-79-1	98%
T12291	Olanzapine D3 is the deuterium labeled Olanzapine.
T70615	TAS-303 化合物 TAS-303	1449371-87-2	98%
T70615	TAS-303 is a selective norepinephrine reuptake inhibitor which displays significant norepinephrine transporter (NET) inhibitory activity toward serotonin or dopa...
T19414	Mebeverine alcohol D5 美贝维林醇 D5	2070015-15-3	98%
T19414	Mebeverine alcohol D5 is the deuterium labeled Mebeverine alcohol.
T12485	Pirfenidone-d5 化合物 T12485	1020719-62-3	98%
T12485	Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.
T71293	Nifuroxazide-d4 化合物 Nifuroxazide-d4	1188487-83-3	98%
T71293	Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It i...
T27097	CTP518 化合物 T27097	1092540-56-1	98%
T27097	CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.
T19273	Debutyldronedarone D7 化合物 T19273		98%
T19273	Debutyldronedarone D7 is deuterium-labeled Debutyldronedarone, which is the main circulating active metabolite of dronedarone in the body.
T19448	N-Desmethyl Clomipramine-d3 化合物 N-Desmethyl Clomipramine-d3	1189971-04-7	98%
T19448	N-Desmethyl Clomipramine-d is the deuterium labeled N-Desmethyl Clomipramine.
T16909	Donafenib 多纳非尼	1130115-44-4	99.88%
T16909	Donafenib (Bay 43-9006 (D3)) 是一种氘标记的 Sorafenib，Sorafenib 是一种多激酶抑制剂(对 Raf-1、B-Raf 和 VEGFR-3 的 IC50 分别为 6 nM、20 nM 和 22 nM)。
T60016	VV116 化合物 VV116	2647442-33-7	99.42%
T60016	VV116 (JT001) 是一种针对呼吸道合胞病毒和 SARS-CoV-2 感染的选择性和口服活性核苷抗病毒剂。
T22301	L-838417 D9 化合物L-838417 D9	1213669-91-0	98.81%
T22301	L-838417 D9 (C-21191) 是 L-838417 的氘代物。其中L-838417 是亚型选择性GABAA 正变构调节剂，在 α2, α3 和 α5 亚型中作为部分激动剂。
T14687	Deucravacitinib 化合物BMS-986165	1609392-27-9	98.52%
T14687	Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂，用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活，可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域，IC50为1.0 nM...