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Targets Recommended: Antibiotic Parasite

43

抑制剂 & 化合物

8

天然产物

7

化合物库

45

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name
L4900 心血管毒性化合物库

131 compounds
131 种心血管毒性化合物的独特集合,可用于毒理学研究;
L7900 成骨分子库

317 compounds
317 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L1700 抗病毒库

1040 compounds
1040 种具有抗病毒活性的化合物的特有集合,是筛选新型抗病毒药的有效工具;可用于高通量筛选和高内涵筛选;
L8800 药物片段库

1119 compounds
1119 种药物片段分子,是FBDD 方法新药筛选的有力工具;
L5700 精选片段库

246 compounds
246 个片段小分子的独特集合,可用于基于片段的筛选和药物发现(FBDD);
L5510 肝脏毒性化合物库

1001 compounds
1001 个肝脏毒性化合物的特有集合,可用于高通量、高内涵筛选,是毒理学研究的良好工具;
DO1200 药物靶点库

53200 compounds
数量多,含53200种小分子化合物,是高通量筛选的有力工具;

化合物库

心血管毒性化合物库
Cat.No: L4900
Compounds: 131
成骨分子库
Cat.No: L7900
Compounds: 317
抗病毒库
Cat.No: L1700
Compounds: 1040
药物片段库
Cat.No: L8800
Compounds: 1119
精选片段库
Cat.No: L5700
Compounds: 246
肝脏毒性化合物库
Cat.No: L5510
Compounds: 1001
药物靶点库
Cat.No: DO1200
Compounds: 53200
Cat. No. Product Name Target Signaling Pathways
T0850 Primaquine diphosphate

Primaquine phosphate,磷酸伯氨喹,Primaquine bisphosphate,磷酸伯安喹

Antibiotic; Parasite Microbiology/Virology
Primaquine diphosphate 是一种合成的 8-氨基喹啉衍生物,具有抗疟特性。它是一种能破坏间日疟原虫和卵形疟原虫肝脏晚期和潜在组织形态的化合物。
T9000 Pyrimorph

Antifungal Microbiology/Virology
Pyrimorph 是一种杀真菌剂,对 oomycetes 具有良好抑菌活性。
T37072 Nitroxynil

4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix

Parasite Microbiology/Virology
Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) 为一种广泛用于研究 Fasciola hepatica 感染的驱虫剂,有效作用于寄生虫的成熟及未成熟阶段。
T3628 Madrasin

DDD00107587

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Madrasin (DDD00107587) 是剪接抑制剂,在体外能够阻止剪接中间体和产物的形成,并干扰剪接体组装途径中的一个或多个早期步骤。它能在体外抑制 pre-mRNA 的剪接,并修饰细胞中内源性 pre-mRNA 的剪接。
T6437 Cefoperazone

头孢哌酮,Cefob,Medocef

Antibacterial; Antibiotic Microbiology/Virology
Cefoperazone (Medocef) 是一种半合成的头孢菌素,有抗菌活性。
T3266 Lumefantrine

Benflumetol,dl-Benflumelol,苯芴醇

Others; Parasite; Autophagy Autophagy; Microbiology/Virology; Others
Lumefantrine (dl-Benflumelol) 是一种抗疟药,用于治疗急性单纯性疟疾。与Artemether 联用,可提高疗效。
T1228 Cefonicid sodium

Monocid sodium,头孢尼西钠,Cefonicid disodium salt

Antibacterial; Antibiotic Microbiology/Virology
Cefonicid sodium (Monocid sodium) 是一种广谱头孢类抗生素, 能抑制细菌细胞壁的形成。
T1213 Piperacillin sodium

哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt

Antibacterial; Antibiotic Microbiology/Virology
Piperacillin sodium salt(CL227193) )是一种β-内酰胺类广谱抗生素。
T1122 Cephalothin sodium

头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin

Antibacterial; Antibiotic Microbiology/Virology
Cephalothin sodium (Cefalotin) 是一种头孢类抗生素, 具有广泛的抗菌活性,抑制革兰氏阳性和阴性菌。
T20730 Cyclanilide

RPA 90946,Finish,RPA90946,RPA-90946

Others Others
Cyclanilide is a plant growth regulator. It is used in cotton at different stages of growth.
T27400 Ganaplacide

KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156

Others Others
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a small number of adults with uncompli
T25815 Mirincamycin HCl

U24,729A,U-24,729A,U-24729 A,U 24729 A,U 24,729A,Mirincamycin hydrochloride

Others Others
Mirincamycin HCl is a close analog of the drug clindamycin used for the treatment of Plasmodium falciparum blood stages.
T32014 GTC365

GTC 365,NSC 177365,GTC-365,NSC-177365,NSC177365

Others Others
GTC365 is an hTERT transcriptional repressor that acts in the early stages of the G-quadruplex folding pathway.
T30214 Austrocortirubin

NSC626307,(+)-Austrocortirubin,NSC 626307,NSC-626307

Others Others
Austrocortirubin is a DNA damage inducer at the G0/G1, S, and G2 cell cycle stages distinct from other DNA damage agents.
T20960 Luxabendazole

HOE 216V

Others Others
Luxabendazole is a benzimidazole carbamate broad-spectrum anthelmintic agent. It has proved to be effective against immature and adult stages of the major gastrointestinal nematodes, cestodes, and trematodes.
T19256 Cyhalofop

Cyhalofop acid,氰氟草酸

Others Others
Cyhalofop (Cyhalofop acid) is a recently registered herbicide in the Indian aryloxyphenoxypropionate group, which can control a variety of grass weeds at different growth stages of rice crops.
T82005 JNJ-8003

RSV Microbiology/Virology
JNJ-8003 为 RSVPolymerase 高效抑制剂,能在 RNA 转录与复制初期阶段抑制核苷酸的聚合作用。
T70507 KAI-407

Others Others
KAI407 is a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. KAI407 showed an activity profile similar to that of primaquine (PQ), efficiently killing the earliest stages of the parasites that become either primary hepatic schizonts or hypnozoites (50% inhibitory concentration [IC50] for hypnozoites, KAI407, 0.69 μM, and PQ, 0.84 μM; for developing liver stages, KAI407, 0.64 μM, and PQ, 0.37 μM). KAI407 may represent a new compou...
T84732 Ipflufenoquin

Others Others
Ipflufenoquin,一种杀虫剂,可有效控制苹果黑星病的原发感染,建议施用时间为半寸绿至坐果期。
T25258 Clazuril

R62690,R 62690,R-62690

Others Others
Clazuril 是苯乙腈衍生物。它是一种合成抗球虫药物,用于动物,尤其是家禽,以治疗球虫病。它对艾美耳球虫物种内源阶段具有杀灭作用。
T37715 Galactosylcerebrosides (bovine)

Galactosylcerebrosides (SGal-CB) 在髓鞘形成的早期阶段可由周围神经系统 (PNS) 中的 Schwann 细胞 (SC) 表达,在鞘中的持续存在对于长期维持其结构完整性至关重要。
T79460 Antimalarial agent 28

Parasite Microbiology/Virology
Antimalarial agent 28 (Compound 2i)为具有针对P. berghei三个发育阶段活性的化合物。该化合物的IC50s针对肝期P. berghei为0.561 μM,对早期配子体为0.14 μM,以及对环期P. berghei为4.34 μM,表明其具有抑制该寄生虫的潜力。
T38895 Zanapezil free base

TAK-147 free base,Zanapezil free base

Others Others
Zanapezil (TAK-147) is a powerful and selective inhibitor of acetylcholine esterase (AChE). It demonstrates significant and reversible inhibition of AChE activity in rat cerebral cortex homogenates (IC50 = 51.2 nM). Furthermore, Zanapezil exhibits moderate inhibition of muscarinic M1 and M2 receptor binding with Ki values of 234 and 340 nM, respectively. This compound holds promise for the investigation of the initial stages of Alzheimer's disease (AD).
T73546 WM382

Others Others
WM382为一种通过口服生效的PMIX/X(双血浆蛋白酶IX/X)抑制剂,其IC50值分别为1.4 nM和0.03 nM。该化合物在疟原虫生命周期多个阶段表现出优异的体内疗效及抗药性。
T75067 Antimalarial agent 19

Parasite Microbiology/Virology
Antimalarial agent 19(compound 6e)是一种活性抗疟疾化合物,对K1型恶性疟原虫和伯氏疟原虫展现出较强的抑制效果,其EC50值分别为0.3 µM和15.3 µM。相较于γ-肝硫平,该化合物具有更好的水溶性、肠道渗透性以及微粒体稳定性。
T62677 Ganaplacide hydrochloride

Others Others
Ganaplacide (KAF156) hydrochloride 是一种首创的、口服具有活力的咪唑哌嗪类抗疟药 (antimalarial)。Ganaplacide hydrochloride 对多种疟原虫(包括耐药寄生虫)有作用。Ganaplacide hydrochloride 对无性和有性血液阶段以及肝脏阶段均具有杀虫效果。
T21735 NNGH

Others Others
NNGH 是基质分解素-1 (MMP-3) 抑制剂。 MMP-3 既是直接转录靶蛋白,也是 Wnt/β-catenin 信号通路的必要组成。 基质金属蛋白酶 (MMP) 在肿瘤进展的晚期发挥着明确的作用。
T62004 (Rac)-Nebivolol

Others Others
(Rac)-Nebivolol ((Rac)-R 065824) 是 Nebivolol 的外消旋异构体。Nebivolol 是一种选择性的β1 肾上腺素能受体拮抗剂(IC50= 0.8 nM)。Nebivolol 显示血管舒张活性。在乙醇引起心脏毒性的早期阶段,Nebivolol 能预防 Nox2/NADPH 氧化酶上调和脂质过氧化。
T9763 MMV666810

Others Others
MMV666810 是一种类似于 MMV390048 的2-氨基吡嗪,5.94 nM 的 MMV666810 对无性寄生虫有效。与早期相比,MMV666810 对晚期配子体细胞的选择性是早期的3.3倍(早期配子体:IC50603 ± 88 nM; 晚期配子体:IC50179 ± 8 nM)。
T22856 IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]

Others Others
IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral
T83044 Antimalarial agent 33

Parasite Microbiology/Virology
Antimalarial agent 33 (compound 5g) 显示针对红细胞期和肝期疟原虫的抗活性,特别是对 K1 恶性疟原虫株,其EC50为1.1 μM。Antimalarial agent 33 还展示出提升的微粒体稳定性(T1/2=29分钟),并且对原代肝细胞未表现出明显的细胞毒效应。
T37040 DiIC1(5)

DiIC1(5)

Others Others
DiIC1(5) is a signal-off fluorescent probe for the detection of mitochondrial membrane potential disruption. It accumulates in mitochondria and its fluorescence intensity decreases when the mitochondrial membrane potential is disrupted. DilC1(5) has been used in combination with a variety of cell damage and cell death markers to classify nine stages of cell death using flow cytometry. It has also been used as a quencher for the detection of serine phosphorylation and tyrosine dephosphorylation p...
T28937 Tebuquine

WR-228,258,WR 228,258,CI 897,CI897,CI-897

Others Others
Tebuquine is an antimalarial agent. Tebuquine is active against P. falciparum in vitro. Tebuquine in vitro shows a chloroquine-like effect, but not in vivo, suggesting that its mode of action in vivo is different from that of chloroquine. Tebuquine has no
T64297 Triton X-100

Others Others
Triton X-100 是一种溶解脂膜的非变性洗涤剂。Triton X-100 通常用于实验室,并在生产过程的不同阶段应用于疫苗。Triton X-100 被列为某些疫苗,包括裂解病毒流感疫苗的赋形剂。Triton X-100 是一种非离子表面活性剂。
T74424 Masavibart

Masavibart (ZRC3308-A7) 是一种靶向SARS-CoV-2的单克隆抗体 (IgG1 型)。Masavibart 对SARS-CoV-2穗状蛋白的RBD 上的非竞争性表位显示出良好的结合亲和力。Masavibart 可按 1:1 与ZRC3308-B10 联合使用,对 COVID-19 的预防以及尚未发展为严重疾病的早期 COVID-19 有效。
T84586 13,14-dihydro-15-keto Prostaglandin E2

13,14-dihydro-15-keto PGE2

Others Others
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) serves as the predominant metabolite of PGE2 in plasma, created through a 15-keto PGE2 intermediate by the action of 15-oxo-PG Δ13 reductase. Unlike its precursor PGE2, this compound exhibits poor binding affinity towards EP2 and EP4 PGE2 receptors (Ki values of 12 and 57 µM, respectively) in CHO cells and fails to stimulate adenylate cyclase activity therein (EC50s >18 and >38 µM, respectively). Concentrations of 13,14-dihydro-...
T61063 SEN177

Others Others
SEN177 在亨廷顿病的研究中显示出潜力。它是谷氨酰胺环化酶 (QPCT) 的有效抑制剂,对谷氨酰胺肽环转移酶 (QPCTL) 的 IC50值为 0.013 μM。SEN177 对人谷氨酰胺环化酶 (hQC) 的 Ki 值为 20 nM。SEN177 显著降低了突变 HTT 寡聚化的早期阶段,并降低了具有 Q80 聚集体的神经元的百分比。
T74425 Nepuvibart

Nepuvibart (ZRC3308-B10) 是一种靶向 SARS-CoV-2的单克隆抗体 (IgG1 型)。Nepuvibart 对 SARS-CoV-2穗状蛋白的 RBD 上的非竞争性表位显示出良好的结合亲和力。Nepuvibart 可按 1:1 与 ZRC3308-A7 联合使用,对 COVID-19 的预防以及尚未发展为严重疾病的早期 COVID-19 有效。
T76845 Sotrovimab

Sotrovimab (VIR 7831)为一种人源化IgG1κ泛冠状病毒(sarbecvirus)单克隆抗体,能够中和SARS-CoV-2、SARS-CoV-1以及其他多种冠状病毒。该药物基于S309研发,拥有较长半衰期,在呼吸道黏膜中展现出较高的生物利用度。Sotrovimab有助于免疫介导的病毒清除,预防Covid-19早期发展。
T69266 Cefcanel free acid

Others Others
Cefcanel is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcanel is active against the species E. coli, K. aerogenes and Proteus mirabilis; H. influenzae and M. catarrhalis has reasonable susceptibility. Cefcanel inhibits 90% of S. aureus strains at 2 µg/ml, irrespective of the presence of a β-lactamase. Cefcanel binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the te...
T79567 Antiviral agent 35

Influenza Virus Microbiology/Virology
Antiviralagent 35 (compound 4d) 作为一种口服抗流感病毒药物,针对流感病毒复制的早期阶段有效。该化合物能够阻断流感病毒引发的ROS积聚、自噬及细胞凋亡,同时在肺部感染的小鼠模型中,抑制RIG-1通路所介导的炎症响应。Antiviralagent 35展现出低细胞毒性(CC50>800 μM,MDCK细胞)且对H1N1(A/Weiss/43)展现出显著的抗病毒活性,EC50为2.28 μM。
T61572 FNDR-20123 free base

Others Others
FNDR-20123 free base 是一种有效、安全、首创的抗疟疾HDAC 抑制剂,对疟原虫和人类 HDAC 的IC50分别为 31 nM 和 3 nM。FNDR-20123 free base 对恶性疟原虫 (Plasmodium falciparum) 无性期 (IC50=41 nM) 和性血期 (雄性配子体 IC50=190 nM) 具有抗疟疾活性。FNDR-20123 free base 抑制 HDAC1,HDAC2,HDAC3,HDAC6,HDAC8 的 IC50分别为 25,29,2,11,282 nM,并在纳摩尔浓度下抑制 III 类 HDAC 亚型。
T38218 1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC

Others Others
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 是一种在生物膜中的磷脂,在 sn-1 和 sn-2 位置分别含有硬脂酸和二十二碳六烯酸。它已被用于研究脂膜的组织和动力学。在超氧化物歧化酶 1 突变体转基因小鼠肌萎缩性脊髓侧索硬化症(ALS)模型中1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 的水平在疾病晚期会在 L5 前角下降。1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 可用于研究生物膜。

化合物

Primaquine diphosphate
Cat.No: T0850
Synonym: Primaquine phosphate,磷酸伯氨喹,Primaquine bisphosphate,磷酸伯安喹
Target: Antibiotic, Parasite
Pyrimorph
Cat.No: T9000
Synonym:
Target: Antifungal
Nitroxynil
Cat.No: T37072
Synonym: 4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix
Target: Parasite
Madrasin
Cat.No: T3628
Synonym: DDD00107587
Target: DNA/RNA Synthesis
Cefoperazone
Cat.No: T6437
Synonym: 头孢哌酮,Cefob,Medocef
Target: Antibacterial, Antibiotic
Lumefantrine
Cat.No: T3266
Synonym: Benflumetol,dl-Benflumelol,苯芴醇
Target: Others, Parasite, Autophagy
Cefonicid sodium
Cat.No: T1228
Synonym: Monocid sodium,头孢尼西钠,Cefonicid disodium salt
Target: Antibacterial, Antibiotic
Piperacillin sodium
Cat.No: T1213
Synonym: 哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt
Target: Antibacterial, Antibiotic
Cephalothin sodium
Cat.No: T1122
Synonym: 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin
Target: Antibacterial, Antibiotic
Cyclanilide
Cat.No: T20730
Synonym: RPA 90946,Finish,RPA90946,RPA-90946
Target: Others
Ganaplacide
Cat.No: T27400
Synonym: KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156
Target: Others
Mirincamycin HCl
Cat.No: T25815
Synonym: U24,729A,U-24,729A,U-24729 A,U 24729 A,U 24,729A,Mirincamycin hydrochloride
Target: Others
GTC365
Cat.No: T32014
Synonym: GTC 365,NSC 177365,GTC-365,NSC-177365,NSC177365
Target: Others
Austrocortirubin
Cat.No: T30214
Synonym: NSC626307,(+)-Austrocortirubin,NSC 626307,NSC-626307
Target: Others
Luxabendazole
Cat.No: T20960
Synonym: HOE 216V
Target: Others
Cyhalofop
Cat.No: T19256
Synonym: Cyhalofop acid,氰氟草酸
Target: Others
JNJ-8003
Cat.No: T82005
Synonym:
Target: RSV
KAI-407
Cat.No: T70507
Synonym:
Target: Others
Ipflufenoquin
Cat.No: T84732
Synonym:
Target: Others
Clazuril
Cat.No: T25258
Synonym: R62690,R 62690,R-62690
Target: Others
Galactosylcerebrosides (bovine)
Cat.No: T37715
Synonym:
Target:
Antimalarial agent 28
Cat.No: T79460
Synonym:
Target: Parasite
Zanapezil free base
Cat.No: T38895
Synonym: TAK-147 free base,Zanapezil free base
Target: Others
WM382
Cat.No: T73546
Synonym:
Target: Others
Antimalarial agent 19
Cat.No: T75067
Synonym:
Target: Parasite
Ganaplacide hydrochloride
Cat.No: T62677
Synonym:
Target: Others
NNGH
Cat.No: T21735
Synonym:
Target: Others
(Rac)-Nebivolol
Cat.No: T62004
Synonym:
Target: Others
MMV666810
Cat.No: T9763
Synonym:
Target: Others
IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]
Cat.No: T22856
Synonym:
Target: Others
Antimalarial agent 33
Cat.No: T83044
Synonym:
Target: Parasite
DiIC1(5)
Cat.No: T37040
Synonym: DiIC1(5)
Target: Others
Tebuquine
Cat.No: T28937
Synonym: WR-228,258,WR 228,258,CI 897,CI897,CI-897
Target: Others
Triton X-100
Cat.No: T64297
Synonym:
Target: Others
Masavibart
Cat.No: T74424
Synonym:
Target:
13,14-dihydro-15-keto Prostaglandin E2
Cat.No: T84586
Synonym: 13,14-dihydro-15-keto PGE2
Target: Others
SEN177
Cat.No: T61063
Synonym:
Target: Others
Nepuvibart
Cat.No: T74425
Synonym:
Target:
Sotrovimab
Cat.No: T76845
Synonym:
Target:
Cefcanel free acid
Cat.No: T69266
Synonym:
Target: Others
Antiviral agent 35
Cat.No: T79567
Synonym:
Target: Influenza Virus
FNDR-20123 free base
Cat.No: T61572
Synonym:
Target: Others
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC
Cat.No: T38218
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN1982 Neoglycyrol

Others Others
Neoglycyrol 是分离自甘草的根中的化合物。它是由传统专利药通脉养心丸中筛选得到,具有潜在心肌保护作用。
T2P2806 Hederacolchiside A1

黑海常春藤苷A1,革叶常春藤皂苷 A1,Raddeanoside R13

Apoptosis; ERK; MEK; Akt; PI3K; Parasite; mTOR Apoptosis; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling
Hederacolchiside A1 (Raddeanoside R13) 是从白头翁中分离的一种有抗利什曼原虫和抗肿瘤增殖活性的天然产物。
T5244 Aminomalonic acid

2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate

Others; Endogenous Metabolite Metabolism; Others
Aminomalonic acid 是氨基内源性代谢产物,在体外能作为来源 Leukemia 5178Y/AR 和小鼠胰腺的L- 天冬酰胺合成酶的高效抑制剂 (Leukemia 5178Y/AR:Ki= 0.0023 M,小鼠胰腺:Ki= 0.0015 M)。它有潜力用作区分黑素瘤转移的不同阶段生物标志物。
TN3899 Drupacine

Others Others
Drupacine and a crude alkaloid extract suppress nematode hatch, activity of mixed life stages, and population numbers on plant roots.
TN4695 Odorine

Others Others
Odorine has potent anti-carcinogenic effect by inhibiting both the initiation and promotion stages of two-stage skin carcinogenesis. It was found to inhibit the growth of the vinblastine-resistant KB cells by enhancing the anticancer activity of vinblastine.
T38515 Ascr#7

Others Others
Ascr#7, an ascaroside-based hormonal compound, plays a significant role in nematode physiology. It is specifically expressed throughout the various stages of nematode development. Notably, ascarosides exhibit the capability to initiate the formation of dauer larvae, which are characterized by their long lifespan and exceptional stress resistance.
TN4696 Odorinol

Antifection Microbiology/Virology
Odorine and odorinol inhibit both the initiation and promotion stages of two-stage skin carcinogenesis. (+)-Odorinol exhibits strong antiviral activity against Ranikhet disease virus (RVD) in chick embryo.
T4415 Katacine

Others Others
Katacine 抑制氧气消耗,并抑制电子通过线粒体呼吸链从氧化底物转移到分子氧的速度。 Katacine 是来自蓼科蓼科蓼属的 A 型原花青素聚合物在不同聚合阶段的混合物。 Katacine 是一种抗缺氧药。

天然产物

Neoglycyrol
Cat.No: TN1982
Synonym:
Target: Others
Hederacolchiside A1
Cat.No: T2P2806
Synonym: 黑海常春藤苷A1,革叶常春藤皂苷 A1,Raddeanoside R13
Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR
Aminomalonic acid
Cat.No: T5244
Synonym: 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate
Target: Others, Endogenous Metabolite
Drupacine
Cat.No: TN3899
Synonym:
Target: Others
Odorine
Cat.No: TN4695
Synonym:
Target: Others
Ascr#7
Cat.No: T38515
Synonym:
Target: Others
Odorinol
Cat.No: TN4696
Synonym:
Target: Antifection
Katacine
Cat.No: T4415
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-01470 SCF Protein, Human, Recombinant

Mast Cell Growth Factor,c-Kit ligand,KITLG,MGF,Stem Cell Fac...

Human E. coli
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-02580 Histone H1 Protein, Human, Recombinant (His)

HSP60,HSP65,CPN60,H1 histone family, member 0,H10,HLD4,HSPD1...

Human E. coli
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes, all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-termin...
TMPJ-00038 IL-7 Protein, Mouse, Recombinant (His)

interleukin-7,白介素,IL-7,IL-7 interleukin-7,PBGF,Lymphopoietin...

Mouse HEK293 Cells
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell...
TMPH-02191 Tetraspanin-2/TSPAN2 Protein, Human, Recombinant

Tetraspanin-2,TSPAN2,Tetraspan NET-3

Human E. coli
May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath. Tetraspanin-2/TSPAN2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is O60636.
TMPH-02127 SNX16 Protein, Human, Recombinant (His)

Sorting nexin-16,SNX16

Human E. coli
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
TMPH-00281 IL-7 Protein, Bovine, Recombinant (His)

IL7,Interleukin-7

Bovine E. coli
Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL-7 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.3 kDa and the accession number is P26895.
TMPJ-01381 ANXA10 Protein, Human, Recombinant

Annexin-10,ANX14,Annexin-14,ANXA10,Annexin A10

Human E. coli
Annexin A10 (ANXA10) contains four Annexin repeats and is a member of the Annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is reported that ANXA10 may be a clinical relevant marker for predicting outcome in both early and advanced stages of bladder cancer.
TMPK-01041 FcRH6 /FCRL6 Protein, Human, Recombinant (hFc)

Fc receptor-like 6,FcRL6,IFGP6,FLJ16056,FcR-like protein 6,F...

Human HEK293 Cells
A surprising number of Fc receptor (FcR) relatives have been recognized recently with the potential capacity to modulate innate and adaptive immune responses. The six human FcR homologs (FcRH1-6), which belong to a phylogenetically conserved gene family, have variable numbers of extracellular immunoglobulin domains of five different subtypes. All but one of these new receptors, FcRH6, are expressed on B cells at different stages in differentiation.
TMPY-00361 Pellino-1 Protein, Human, Recombinant (His & GST)

pellino E3 ubiquitin protein ligase 1,PRISM

Human Baculovirus Insect Cells
PELI is a family of E3 ubiquitin ligases that regulate protein activity through a post-translational modification, ubiquitination. PELI1 may function to control inadvertent activation of RIP3, thus preventing aberrant cell death and maintaining cellular homeostasis. PELI1 might participate in B-cell maturation or oncogenic activation of aggressive B-cell lymphomas, both during and after germinal center stages.
TMPK-01268 Complement C2 Protein, Cynomolgus, Recombinant (His)

C2,CO2,Complement C2,C3/C5 convertase,ARMD14

Cynomolgus HEK293 Cells
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC.
TMPJ-01327 ATG10 Protein, Human, Recombinant (His, T7)

ATG10,APG10-Like,Ubiquitin-Like-Conjugating Enzyme ATG10,Aut...

Human E. coli
Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or A...
TMPH-02854 Jagged 1 Protein, Mouse, Recombinant (His & Myc & SUMO)

Protein jagged-1,Jag1

Mouse E. coli
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. May regulate fibroblast growth factor-induced angiogenesis. Jagged 1 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.6 ...
TMPJ-00855 GLUL Protein, Human, Recombinant (His)

GLUL,GS,Glutamine Synthetase,Glutamate-Ammonia Ligase,GLNS,G...

Human E. coli
Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of energy and that takes part in cell prolifetation, inhibition of apoptosis, and cell signaling. Glutamine Synthetase is expressed during early fetal stages, and has a role in maintaining body PH by removing ammonia from circulation. Mutations in the GLUL gene are related to congenital glutamine deficiency.
TMPK-00248 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)

DCR2,TNFRSF10D,RSF10D,CD264,TRUNDD,TRAILR4

Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 19.4 kDa and t...
TMPJ-00703 Gankyrin Protein, Human, Recombinant

PSMD10,Gankyrin,26S Proteasome Non-ATPase Regulatory Subunit...

Human E. coli
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.
TMPK-00672 CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)

CTGRP,CTGF,IBP-8,CCN2,NOV2,HCS24,IGFBP8,Fisp12

Rhesus HEK293 Cells
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His ta...
TMPK-01000 CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated

CTGF,CCN2,IBP-8,IGFBP8,Fisp12,CTGRP,HCS24,MGC102839,NOV2

Human HEK293 Cells
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells wi...
TMPJ-00897 TPSB2 Protein, Mouse, Recombinant (His)

Tryptase-2,Mast cell protease 6,Tryptase beta-2,Tryptase β-2...

Mouse HEK293 Cells
Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It plays a role in innate immunity. Tpsb2 can be detected primarily in skin during embryogenesis. Tpsb2 can not be detected at early embryonic stages but is abundantly expressed in later stages with a peak at E17.5-E18.5. Tryp...
TMPH-03648 Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc)

Cruzaine,Cruzipain,Major cysteine proteinase

Trypanosoma cruzi E. coli
Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.; The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle. Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weig...
TMPY-03502 PAX8 Protein, Human, Recombinant (His)

paired box 8

Human E. coli
PAX8 gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. PAX8 is involved in thyroid follicular cell development and expression of thyroid-specific genes. Also functions in very early stages of kidney organogenesis. Mutations in PAX8 gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyr...
TMPY-04985 TMPRSS11D Protein, Human, Recombinant (His)

transmembrane protease, serine 11D,HAT

Human HEK293 Cells
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated with NSCLC patients' clinical characteristics and overall survival. Both TMPRSS11D mRNA and protein expression levels were significantly higher in NSCLC tumorous tissues than in adjacent normal tissues. High TMPRSS11D protein expression was associated with high TNM stages, and hi...
TMPK-00096 FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated

FGF-10,KGF2

Human E. coli
Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more suscept...
TMPK-00249 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated

TNFRSF10D,CD264,TRUNDD,DCR2,RSF10D,TRAILR4

Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is ...
TMPJ-00563 LGALS3 Protein, Human, Recombinant (His)

Galactose-Specific Lectin 3,LGALS3,35 kDa Lectin,Gal-3,MAC2,...

Human HEK293 Cells
Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma, and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic...
TMPJ-00610 hFcRL1 Protein, Mouse, Recombinant (His)

FcR-like protein 1,BXMAS1-like protein 1,mIFGP1,Fc receptor ...

Mouse HEK293 Cells
Mouse Fc receptor-like protein 1 (FCRL1) is a single-pass type I membrane protein. It is expressed in B-cells at the various stages of differentiation. Mouse FCRL1 consists of a 203 amino acid (aa) extracellular domain (ECD) with two Ig‑like domains, a 21 aa transmembrane segment, and a 103 aa cytoplasmic domain with two immunotyrosine activation motifs (ITAMs). FCRL1 is likely not a receptor for immunoglobulin. It may function as an activating coreceptor in B-cells and B-cells differentiation.
TMPH-02648 PKDCC Protein, Mouse, Recombinant (His & Myc)

Extracellular tyrosine-protein kinase PKDCC,Vertebrate lones...

Mouse Baculovirus Insect Cells
Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membr...
TMPJ-00905 DTYMK Protein, Human, Recombinant (His)

DTYMK,TMPK,dTMP kinase,Thymidylate kinase,CDC8,TYMK

Human HEK293 Cells
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest ...
TMPY-01346 Psoriasin/S100A7 Protein, Human, Recombinant

S100 calcium binding protein A7,PSOR1,S100A7c

Human E. coli
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role...
TMPJ-01190 SPESP1 Protein, Human, Recombinant (His)

Sperm Equatorial Segment Protein 1,Glycosylated 38 kDa Sperm...

Human HEK293 Cells
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may intera...
TMPY-02393 Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His)

thimet oligopeptidase 1,EP24.15,AI131655,AI327041

Mouse Baculovirus Insect Cells
THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, highly expressed in the brain, kidneys and neuroendocrine tissue, THOP1 has been proposed to metabolize peptides within cells, thereby affecting antigen presentation and G protein-coupled receptor signal transduction. Its substrates is gonadotrophin-releasing hormone (GnRH), an impor...
TMPJ-00445 IBSP Protein, Mouse, Recombinant (His)

BNSP,IBSP,Integrin binding sialoprotein,Cell binding sialopr...

Mouse HEK293 Cells
Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesized as a 324 amino acid (aa) precursor that contains a 16 aa signal sequence and a 308 aa mature region. The mature segment is divided into a basic N‑terminus (aa 17 ‑ 62), a central region (aa 63 ‑ 233), and an acidic C‑terminus (aa 234 ‑ 317). IBSP is highly glycosylated, sulfate...
TMPY-03861 Amelotin Protein, Human, Recombinant (mFc)

amelotin,UNQ689

Human HEK293 Cells
Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface which protects against the constant microbiological challenge to the periodontium. TNF-α stimulates AMTN gene transcription in human gingival epithelial cells via C/EBP1, C/EBP2, and YY1 elements in the human AMTN gene promoter.AMTN mRNA levels increased at 6 h and reached maximum a...
TMPH-01526 KMT2E Protein, Human, Recombinant (His & Myc)

Inactive histone-lysine N-methyltransferase 2E,Myeloid/lymph...

Human E. coli
Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription. Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4' (H3K4me3). Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Also acts as an important cell cycle regulator, participating in cell cycle r...
TMPY-01401 Cyclin A1 Protein, Human, Recombinant (His)

cyclin A1,CT146

Human Baculovirus Insect Cells
Cyclin A1 is a member of the highly conserved cyclin family that is characterized by a dramatic periodicity in protein abundance, and belongs to the A-type cyclin subfamily. The mammalian A-type cyclin family consists of two members: cyclin A1 and cyclin A2. Different cyclins exhibit distinct expression. Cyclin A1 is expressed in mice exclusively in the germ cell lineage and high rate of cyclinA1 is found in human testis and certain myeloid leukaemia cells. Cyclin A1 is primarily function in the...
TMPY-00090 SPARCL1 Protein, Mouse, Recombinant (His)

Sc1,SPARC like 1,mast9,hevin,Ecm2

Mouse HEK293 Cells
SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasc...
TMPY-02497 S100A15 Protein, Mouse, Recombinant (His & MBP)

S100a17l1,Gm1020,S100a15a,AY465109,S100A7f,S100A7L1,S100 cal...

Mouse E. coli
Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF-hand calcium-binding proteins and was recently identified in psoriasis, where it is significantly upregulated in lesional skin. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesti...
TMPY-02125 CCL6 Protein, Mouse, Recombinant (His)

Scya6,MRP-1,c10,RP23-320E6.4,chemokine (C-C motif) ligand 6

Mouse HEK293 Cells
Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is involved in the chronic stages of host defense reactions. C10 chemokine rapidly promotes disease resolution in the cecal ligation and puncture (CLP) model through its direct effects on the cellular events critically involved in host defense during septic peritonitis. CCL6 appears ...
TMPJ-00669 Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)

Sialic acid-binding Ig-like lectin 5,OB-BP2,Obesity-binding ...

Human HEK293 Cells
Human Siglec-5 are Itype(Igtype) lectins belonging to the Ig superfamily,They are characterized by an N terminal Ig-like V type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2 type domains. SIGLEC5 has also been designated CD170, they are expressed by monocytic or myeloid lineage cells, and also found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. SIGLEC5 are...
TMPY-01763 Cadherin 16/CDH16 Protein, Human, Recombinant (His)

UNQ695/PRO1340,cadherin 16

Human HEK293 Cells
KSP-Cadherin/Cadherin-16 is a member of the cadherin superfamily, calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playi...
TMPY-03397 TPPP3 Protein, Human, Recombinant (His)

CGI-38,TPPP3,p25gamma,tubulin polymerization-promoting prote...

Human E. coli
TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons, Tppp3 is expressed in cells at the circumference of the developing tendons, likely the progenitors of connective tissues that surround tendons: the tendon sheath, epitenon, and paratenon. Tppp3 is also expressed in forming synovial joints. The onset of Tppp3 expression in joint...
TMPY-01416 OLFM4 Protein, Human, Recombinant (His)

hGC-1,GC1,OLM4,bA209J19.1,GW112,olfactomedin 4,OlfD,hOLfD,UN...

Human HEK293 Cells
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed...
TMPH-02275 Lck Protein, Human, Recombinant (His)

Proto-oncogene Lck,T cell-specific protein-tyrosine kinase,T...

Human E. coli
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules...
TMPH-01502 Humanin Protein, Human, Recombinant (GST)

Humanin,Humanin mitochondrial,MT-RNR2

Human E. coli
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPH-01503 Humanin Protein, Human, Recombinant (hFc)

MT-RNR2,Humanin,Humanin mitochondrial

Human HEK293 Cells
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....

重组蛋白

SCF Protein, Human, Recombinant
Cat.No: TMPJ-01470
Species: Human
Expression System: E. coli
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
Histone H1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02580
Species: Human
Expression System: E. coli
IL-7 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00038
Species: Mouse
Expression System: HEK293 Cells
Tetraspanin-2/TSPAN2 Protein, Human, Recombinant
Cat.No: TMPH-02191
Species: Human
Expression System: E. coli
SNX16 Protein, Human, Recombinant (His)
Cat.No: TMPH-02127
Species: Human
Expression System: E. coli
IL-7 Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00281
Species: Bovine
Expression System: E. coli
ANXA10 Protein, Human, Recombinant
Cat.No: TMPJ-01381
Species: Human
Expression System: E. coli
FcRH6 /FCRL6 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01041
Species: Human
Expression System: HEK293 Cells
Pellino-1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-00361
Species: Human
Expression System: Baculovirus Insect Cells
Complement C2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01268
Species: Cynomolgus
Expression System: HEK293 Cells
ATG10 Protein, Human, Recombinant (His, T7)
Cat.No: TMPJ-01327
Species: Human
Expression System: E. coli
Jagged 1 Protein, Mouse, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02854
Species: Mouse
Expression System: E. coli
GLUL Protein, Human, Recombinant (His)
Cat.No: TMPJ-00855
Species: Human
Expression System: E. coli
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00248
Species: Human
Expression System: HEK293 Cells
Gankyrin Protein, Human, Recombinant
Cat.No: TMPJ-00703
Species: Human
Expression System: E. coli
CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00672
Species: Rhesus
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01000
Species: Human
Expression System: HEK293 Cells
TPSB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00897
Species: Mouse
Expression System: HEK293 Cells
Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc)
Cat.No: TMPH-03648
Species: Trypanosoma cruzi
Expression System: E. coli
PAX8 Protein, Human, Recombinant (His)
Cat.No: TMPY-03502
Species: Human
Expression System: E. coli
TMPRSS11D Protein, Human, Recombinant (His)
Cat.No: TMPY-04985
Species: Human
Expression System: HEK293 Cells
FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
Cat.No: TMPK-00096
Species: Human
Expression System: E. coli
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00249
Species: Human
Expression System: HEK293 Cells
LGALS3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00563
Species: Human
Expression System: HEK293 Cells
hFcRL1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00610
Species: Mouse
Expression System: HEK293 Cells
PKDCC Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02648
Species: Mouse
Expression System: Baculovirus Insect Cells
DTYMK Protein, Human, Recombinant (His)
Cat.No: TMPJ-00905
Species: Human
Expression System: HEK293 Cells
Psoriasin/S100A7 Protein, Human, Recombinant
Cat.No: TMPY-01346
Species: Human
Expression System: E. coli
SPESP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01190
Species: Human
Expression System: HEK293 Cells
Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02393
Species: Mouse
Expression System: Baculovirus Insect Cells
IBSP Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00445
Species: Mouse
Expression System: HEK293 Cells
Amelotin Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03861
Species: Human
Expression System: HEK293 Cells
KMT2E Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01526
Species: Human
Expression System: E. coli
Cyclin A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01401
Species: Human
Expression System: Baculovirus Insect Cells
SPARCL1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00090
Species: Mouse
Expression System: HEK293 Cells
S100A15 Protein, Mouse, Recombinant (His & MBP)
Cat.No: TMPY-02497
Species: Mouse
Expression System: E. coli
CCL6 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02125
Species: Mouse
Expression System: HEK293 Cells
Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)
Cat.No: TMPJ-00669
Species: Human
Expression System: HEK293 Cells
Cadherin 16/CDH16 Protein, Human, Recombinant (His)
Cat.No: TMPY-01763
Species: Human
Expression System: HEK293 Cells
TPPP3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03397
Species: Human
Expression System: E. coli
OLFM4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01416
Species: Human
Expression System: HEK293 Cells
Lck Protein, Human, Recombinant (His)
Cat.No: TMPH-02275
Species: Human
Expression System: E. coli
Humanin Protein, Human, Recombinant (GST)
Cat.No: TMPH-01502
Species: Human
Expression System: E. coli
Humanin Protein, Human, Recombinant (hFc)
Cat.No: TMPH-01503
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIJ-0157 Cefoperazone-d5

Cefoperazone-d5 是 Cefoperazone 的氘代化合物。Cefoperazone 的 CAS 号为 62893-19-0。Cefoperazone是一种半合成的头孢菌素,有抗菌活性。
TMIJ-0072 Lumefantrine-d9

Lumefantrine-d9 是 Lumefantrine 的氘代化合物。Lumefantrine 的 CAS 号为 82186-77-4。Lumefantrine是一种抗疟药,用于治疗急性单纯性疟疾。与Artemether联用,可提高疗效。

同位素标记化合物

Cefoperazone-d5
Cat.No: TMIJ-0157
Synonym:
Target:
Lumefantrine-d9
Cat.No: TMIJ-0072
Synonym:
Target:
TargetMol Loading
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