|
TMPH-00292
|
PGLYRP1/PGRP-S Protein, Bovine, Recombinant (His & Myc)
PGLYRP1,Oligosaccharide-binding protein,Peptidoglycan re...
|
Bovine
|
E. coli
|
|
PGLYRP1/PGRP-S Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.3 kDa and the accession number is Q8SPP7. |
|
TMPH-02111
|
SRP72 Protein, Human, Recombinant (GST)
SRP72,Signal recognition particle 72 kDa protein,Si...
|
Human
|
E. coli
|
|
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. SRP72 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 101.1 kDa and the accession numb... |
|
TMPH-01736
|
PGLYRP2 Protein, Human, Recombinant (His)
PGLYRP2,Peptidoglycan recognition protein long,Pept...
|
Human
|
P. pastoris (Yeast)
|
|
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 62.0 kDa and the accession number is Q96PD5. |
|
TMPH-01737
|
PGLYRP2 Protein, Human, Recombinant (His & SUMO)
N-acetylmuramoyl-L-alanine amidase,Peptidoglycan recogni...
|
Human
|
E. coli
|
|
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 76.0 kDa and the accession number is Q96PD5. |
|
TMPH-00507
|
PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc)
PGRP-SC2,Peptidoglycan-recognition protein SC2
|
Fruit fly
|
E. coli
|
|
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN). Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments. Has no direct bacteriolytic activity. PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9V4X2. |
|
TMPY-04988
|
PGLYRP4 Protein, Human, Recombinant (His)
PGRPIB,SBBI67,PGLYRPIβ,peptidoglycan recognition pr...
|
Human
|
HEK293 Cells
|
|
PGLYRP4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.2 kDa and the accession number is Q96LB8-1. |
|
TMPY-02163
|
PGLYRP1 Protein, Mouse, Recombinant (His)
Tnfsf3l,peptidoglycan recognition protein 1,PGRP,Ta...
|
Mouse
|
HEK293 Cells
|
|
Peptidoglycan recognition protein 1, also known as Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP and TNFSF3L, is a secreted protein that belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 / PGLYRP is highly expressed in bone marrow. It is weakly expressed in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. PGLYRP1 / PGLYRP is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-posi... |
|
TMPJ-00727
|
PGK1 Protein, Human, Recombinant (His)
Phosphoglycerate kinase 1,Primer recognition protei...
|
Human
|
HEK293 Cells
|
|
Phosphoglycerate kinase 1(PGK1) is an enzyme. It is mainly expressed in spermatogonia and Localized on the principle piece in the sperm. Its expression significantly decreased in the testis of elderly men. PGK1 involved in a critical energy-producing process known as glycolysis. It helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 may ... |
|
TMPH-01498
|
HJURP Protein, Human, Recombinant (His & SUMO)
14-3-3-associated AKT substrate,Up-regulated in lung cancer ...
|
Human
|
E. coli
|
|
HJURP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. |
|
TMPY-01009
|
TGFBI Protein, Human, Recombinant (His)
CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be...
|
Human
|
HEK293 Cells
|
|
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys... |
|
TMPY-01850
|
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC119875,carcinoembryonic antigen ...
|
Human
|
HEK293 Cells
|
|
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... |
|
TMPY-03650
|
BirA Protein, E. coli, Recombinant (His & MBP)
BirA,dhbB,bioR
|
E. coli
|
E. coli
|
|
The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these proteins to be tetramerized by binding to streptavidin. Because of the specificity of the biotinylation at the C terminus, the orientation of the membrane proteins on the streptavidin is equivalent to that of the native protein on the cell surface. These tetrameric proteins can be use... |
|
TMPY-02904
|
TLR4 Protein, Human, Recombinant (His)
TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284
|
Human
|
Baculovirus Insect Cells
|
|
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed... |
|
TMPK-00255
|
CD209/DC-SIGN Protein, Human, Recombinant (His)
CD209,DC-SIGN,CLEC4L,CD209 molecule,DC-SIGN1,MGC129965,CDSIG...
|
Human
|
HEK293 Cells
|
|
C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as SARS, SARS-CoV-2, bacteria, fungi and parasites. Pathogens exploit CD209 family proteins to promote infection and evade the immune recognition system. |
|
TMPY-04103
|
COLEC10 Protein, Cynomolgus, Recombinant (hFc)
collectin sub-family member 10 (C-type lectin)
|
Cynomolgus
|
HEK293 Cells
|
|
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. COLEC10 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 ... |
|
TMPH-01291
|
ERVK-7 Protein, Human, Recombinant (His)
Endogenous retrovirus group K member 7 Env polyprotein,HERV-...
|
Human
|
E. coli
|
|
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane. |
|
TMPH-01289
|
ERVK-6 Protein, Human, Recombinant (E. coli, His)
HERV-K108 envelope protein,Endogenous retrovirus group K mem...
|
Human
|
E. coli
|
|
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane... |
|
TMPY-03996
|
COLEC10 Protein, Mouse, Recombinant (hFc)
collectin sub-family member 10 (C-type lectin),CL-L1
|
Mouse
|
HEK293 Cells
|
|
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. COLEC10 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mamma... |
|
TMPH-01290
|
ERVK-6 Protein, Human, Recombinant (His)
HERV-K(HML-2.HOM) envelope protein,ERVK-6,HERV-K(C7) envelop...
|
Human
|
Baculovirus Insect Cells
|
|
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane... |
|
TMPH-01203
|
DCAF16 Protein, Human, Recombinant (His & Myc)
C4orf30,DCAF16,DDB1- and CUL4-associated factor 16
|
Human
|
E. coli
|
|
Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins. DCAF16 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is Q9NXF7. |
|
TMPH-03521
|
MecA Protein, S. aureus, Recombinant (His & SUMO)
Adapter protein MecA,mecA
|
Staphylococcus aureus
|
E. coli
|
|
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. MecA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.3 kDa and the accession number is P60186. |
|
TMPJ-01447
|
Apolipoprotein B-100/APOB Protein, Human, Recombinant (His)
APOB,ApolipoproteinB-100
|
Human
|
E. coli
|
|
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. |
|
TMPH-00650
|
LptE Protein, E. coli, Recombinant (His & Myc)
LPS-assembly lipoprotein LptE,lptE
|
E. coli
|
E. coli
|
|
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. |
|
TMPY-03977
|
DAP10 Protein, Human, Recombinant (mFc)
PIK3AP,DAP10,hematopoietic cell signal transducer,KAP10
|
Human
|
HEK293 Cells
|
|
HCST (Hematopoietic Cell Signal Transducer, also known as DAP1) is a Protein Coding gene. HCST belongs to the DAP10 family. It is a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. HCST may be part of the immune recognition receptor complex. This receptor plays a major role in triggering cytotoxicity against target cells expressing cell sur... |
|
TMPH-01326
|
FBXO44 Protein, Human, Recombinant (His & Myc)
F-box only protein 44,F-box/G-domain protein 3,F-box protein...
|
Human
|
E. coli
|
|
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. FBXO44 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9H4M3. |
|
TMPJ-01217
|
Mgl2 Protein, Mouse, Recombinant (His)
Macrophage Galactose-type C-lectin 2,Mgl2,CD301b,Macrophage ...
|
Mouse
|
HEK293 Cells
|
|
Macrophage galactose N-acetyl-galactosamine-specific lectin 2(Mgl2), also known as CD301b, is a 38 kDa member that belongs to the C-type lectin family. Two MGL proteins are encoded by separate genes in the mouse, but share 91% amino acid (aa) identity in the extracellular domain (ECD). Only one MGL occurs in human and rat and this MGL is structurally more similar to mouse MGL1 than MGL2. However, human MGL and mouse MGL2 both bind specifically to terminal GalNAc residues, in contrast with mouse... |
|
TMPH-02651
|
Fbxo3 Protein, Mouse, Recombinant (His & Myc)
Muscle atrophy F-box protein,Atrogin-1,Fbxo32,F-box only pro...
|
Mouse
|
E. coli
|
|
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
|
TMPK-00144
|
CEACAM3 Protein, Human, Recombinant (hFc)
CEACAM3,CGM1,CEA,CD66d
|
Human
|
HEK293 Cells
|
|
The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac. |
|
TMPK-00789
|
CD228 Protein, Human, Recombinant (His)
MFI2,MAP97,MELTF,Melanotransferrin,CD228
|
Human
|
HEK293 Cells
|
|
Melanotransferrin is typically overexpressed in melanoma cells compared to other cell types - including cancer cells - and is efficiently sorted and secreted with nanovesicles, or so-called exosomes, due to its membrane-anchoring by a glycosylphosphatidylinositol. Melanotransferrin is exposed on the surface of exosomes and is accessible for antibody recognition. |
|
TMPJ-00689
|
EIF1B Protein, Human, Recombinant (His)
Protein Translation Factor SUI1 Homolog GC20,EIF1B,Eukaryoti...
|
Human
|
E. coli
|
|
Eukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulating the activity of ribosomal subunits 43S, 48S and 40S. EIF1B enables 43S ribosomal complexes to distinguish between cognate and near-cognate initiation codons, perceiving the nucleotide content of initiation codons. |
|
TMPH-02163
|
Syncytin-1 Protein, Human, Recombinant (His & SUMO)
Endogenous retrovirus group W member 1,Enverin,Env-W,Syncyti...
|
Human
|
E. coli
|
|
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.; Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor r... |
|
TMPH-01313
|
EIF4G1 Protein, Human, Recombinant (His)
EIF4G,eIF-4-gamma 1,Eukaryotic translation initiation factor...
|
Human
|
P. pastoris (Yeast)
|
|
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation. EIF4G1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 41.6 kDa and the accession number is Q04637. |
|
TMPK-01228
|
MARCO Protein, Human, Recombinant (His)
Ly112,SCARA2,AI323439,MARCO
|
Human
|
HEK293 Cells
|
|
Macrophage receptor with collagenous structure (MARCO) is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). MARCO contributes to normal cholesterol uptake in macrophages; therefore, in the absence of MARCO, macrophages are more susceptible to a greater inflammatory response by particulates known to cause NLRP3 inflammasome activation and the effect is due to increased LMP. |
|
TMPK-00632
|
MD2/LY96 Protein, Cynomolgus, Recombinant (His)
ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2
|
Cynomolgus
|
E. coli
|
|
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0. |
|
TMPJ-00377
|
VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated
INCAM-100,Vascular cell adhesion protein 1,V-CAM 1,CD106,VCA...
|
Human
|
HEK293 Cells
|
|
VCAM-1 (CD106, INCAM-110) is a cell adhesion molecule and a member of the immunoglobulin superfamily. It's important function is a recognition of cell-cell. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation。 |
|
TMPK-00837
|
Galectin-3 Protein, Human, Recombinant (His)
LGALS2,GAL3,MAC2GAL3,Galectin3,L31,Mac-2,GALBPCBP35,GALIG,CB...
|
Human
|
HEK293 Cells
|
|
Human Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). |
|
TMPK-01049
|
CLEC7A Protein, Mouse, Recombinant (hFc)
CLECSF12,DC-associated C-type lectin 1,Dectin-1,Beta-glucan ...
|
Mouse
|
HEK293 Cells
|
|
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders. |
|
TMPH-01312
|
EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)
eIF-4G 1,EIF4G,Eukaryotic translation initiation factor 4 ga...
|
Human
|
E. coli
|
|
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation. EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc) is expressed in E. coli expression system with N-10xHis-B2M-JD and C-Myc tag. The predicted molecular weight is 46.6 kDa and the accession nu... |
|
TMPK-00059
|
CD94 Protein, Human, Recombinant (His & Avi), Biotinylated
NK cell receptor,CD94,KP43,KLRD1
|
Human
|
HEK293 Cells
|
|
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.8 kDa and the accession number is Q13241-1. |
|
TMPJ-00789
|
Flagellin Protein, Salmonella Typhimurium, Recombinant
flaF,Phase 1-I flagellin,Flagellin,fliC,hag
|
Salmonella typhimurium
|
E. coli
|
|
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin is used as an effective systemic or mucosal adjuvant to stimulate the immune system. Flagellin is an agonist of Toll-like receptor 5 (TLR5), a pattern recognition receptor (PRR) of the innate immune system expressed on the basolateral surface of intestinal epithelial cells and o... |
|
TMPK-01242
|
MD2/LY96 Protein, Human, Recombinant (His)
MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY96,ESOP1
|
Human
|
E. coli
|
|
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1. |
|
TMPJ-00786
|
ITGB1 Protein, Human, Recombinant (aa 21-728, His)
Integrin Beta-1,VLA-4 Subunit β,Fibronectin Receptor Subunit...
|
Human
|
HEK293 Cells
|
|
Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and ree... |
|
TMPJ-00525
|
LGALS14 Protein, Human, Recombinant (His)
Galectin-14,PPL13,Placental Protein 13-Like,LGALS14,Gal-14,C...
|
Human
|
HEK293 Cells
|
|
Galectin-14 is a member of the Galectin family of carbohydrate binding proteins. The members of Galectin family contain one or two carbohydrate recognition domains, which can bind β-Galactoside. LGALS14 is expressed intracellularly in placenta and eosinophils, and is released by eosinophils following allergen stimulation. LGALS14 may be involved in the development of allergic inflammation. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. |
|
TMPK-00058
|
CD94 Protein, Human, Recombinant (His & Avi)
KLRD1,KP43,NK cell receptor,CD94
|
Human
|
HEK293 Cells
|
|
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.8 kDa and the accession number is Q13241-1. |
|
TMPJ-00527
|
SP-D Protein, Human, Recombinant (His)
Lung Surfactant Protein D,SFTP4,COLEC7,SFTPD,PSP-D,SP-D,Pulm...
|
Human
|
HEK293 Cells
|
|
Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognition domain (CRD), a structure that places it in a subset of pattern recognition proteins termed defense collagens. SP-D is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures and induced in cardiac smooth muscle and endothelial cells. ... |
|
TMPH-03398
|
VCAM-1 Protein, Rat, Recombinant (His)
Vcam1,Vascular cell adhesion protein 1
|
Rat
|
E. coli
|
|
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM-1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.4 ... |
|
TMPH-00550
|
Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc)
20 kDa protein,Viral interleukin-10 homolog,Protein BCRF1
|
EBV
|
E. coli
|
|
Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. Inhibits IFN-gamma synthesis. Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted m... |
|
TMPK-00790
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Complement factor H/CFH Protein, Human, Recombinant (His)
ARMD4,AHUS1,H factor 1,HF1,AMBP1,FH,FHL1,HUS,CFHL3,ARMS1,HF2...
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Human
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HEK293 Cells
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Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self)... |
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TMPH-02136
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SPSB1 Protein, Human, Recombinant (His)
SPSB1,SPRY domain-containing SOCS box protein 1
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Human
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E. coli
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Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2. Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5. |
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TMPJ-00345
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IGF2BP-2 Protein, Human, Recombinant (His)
IGF-II mRNA-Binding Protein 2,IGF2 mRNA-Binding Protein 2,He...
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Human
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E. coli
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Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replicat... |
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