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Search Results for " phenolic "
Targets Recommended: Others Ligand for E3 Ligase

22

抑制剂 & 化合物

87

天然产物

2

化合物库

3

重组蛋白

6

同位素标记化合物

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Cat. No. Product Name
L6100 天然多酚类化合物库

635 compounds
635 个天然多酚化合物的独特集合,可用于高通量、高内涵筛选;
L6820 烟草单体化合物库

747 compounds
747种烟草单体化合物的独特集合,可用于高通量筛选和高内涵筛选

化合物库

天然多酚类化合物库
Cat.No: L6100
Compounds: 635
烟草单体化合物库
Cat.No: L6820
Compounds: 747
Cat. No. Product Name Target Signaling Pathways
T17877 VH032-cyclopropane-F

VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101

Others; Ligand for E3 Ligase Others; PROTAC
VH032-cyclopropane-F 是基于 VH032 的 VHL 配体。它能够利用 linker 与靶蛋白配体连接,得到 PROTAC 分子,如 PROTAC 1。PROTAC 1 是 SMARCA2 和 SMARCA4 的部分降解剂。
T3097 Mycophenolic Acid Impurity

马替麦考酚酸杂质,5,7-dihydroxy-4-methylphthalide

Others Others
Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) 是一种免疫抑制药物和有效的抗增殖剂,可用于代替旧的抗增殖剂 azathioprine。它通常用作三联疗法的一部分,包括钙调神经磷酸酶抑制剂(ciclosporin 或 tacrolimus)和prednisolone。它还可用于研究选择表达编码 XGPRT(黄嘌呤鸟嘌呤磷酸核糖基转移酶)的大肠杆菌基因的动物细胞。
T61099 Mycophenolic acid sodium

Others Others
Mycophenolic acid sodium is a potent uncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH), exhibiting an EC50 of 0.24 μM. It has broad antiviral activity against RNA viruses, including influenza. Additionally, mycophenolic acid sodium possesses immunosuppressive properties and exerts antiangiogenic and antitumor effects [1][2].
T124275 Mycophenolic acid IV

Others Others
Mycophenolic acid IV 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124275,CAS号为 74838-16-7。
T0538 3-Methylindolin-2-one

3-Methyloxindole,3-Methyl-2-oxindole,3-甲基羟基吲哚

Others; Endogenous Metabolite; AChE Metabolism; Neuroscience; Others
3-Methyloxindole 是一种酚类病毒诱导剂,是一种乙酰胆碱酯酶抑制。
T4287 Succinobucol

Probucol monosuccinate,AGI-1067

Antioxidant; Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
Succinobucol (Probucol monosuccinate) 是酚类抗氧化剂,具有抗炎、抗血小板聚集活性。
T9443 2-Chloro-4-nitrophenol

Others Others
2-Chloro-4-nitrophenol 是一种酚类化合物。它是环氧合酶(COX)的抑制剂,可以减少前列腺素的产生,从而减轻炎症和疼痛。
T1350 4-Butoxyphenol

4-正丁氧基苯酚,P-Butoxyphenol

Others Others
4-Butoxyphenol (P-Butoxyphenol) 是一种在科学和工业领域有广泛应用的酚类化合物。它经常用于合成其他化合物,如4-丁氧基苯乙酸和4-丁氧基苯乙腈;还用于合成药物,如布洛芬和萘普生。
T31875 Fragilin

Others Others
Fragilin is a phenolic glycoside.
T35514 2,6-Dibromoquinone-4-chloroimide

2,6-Dibromoquinone-4-chloroimide is a colorimetric dye for the detection of phenolic compounds. It produces an indigo dye upon reacting with phenolic compounds at a pH of approximately 9.4. 2,6-Dibromoquinone-4-chloroimide has been used as a Gibbs reagent for the colorimetric detection of phenolic compounds. It has also been used in chromogenic reactions for the quantitative colorimetric detection of aflatoxins, causing colorless aflatoxins to become green with an absorption band at 673 nm.
T32625 Leiocarposide

Lejokarpozyd

Others Others
Leiocarposide is a phenolic bisglucoside from Solidago virgaurea L.
T20764 Dienestrol diacetate

NSC 81279,NSC81279,Cycladiene,Retalon-oral,Oestrasid C,NSC-81279

Others Others
Dienestrol diacetate, a derivative of the synthetic non-steroid phenolic compound, DIENESTROL, exhibits estrogenic activities.
T32528 Lacticolorin

Others Others
Lacticolorin is a phenolic glucoside ester; metabolite of Protea lacticolor Salisb.
T12828 Salicortin

NF-κB; JNK MAPK; NF-κB
Salicortin is a phenolic glycoside isolated from many plants such as Populus and Salix species, has anti-adipogenic, anti-amnesic, and immune-modulatory activity.
T14861 Camobucol

AGIX 4207

Others Others
Camobucol is an orally active, anti-inflammatory compound. It also is a phenolic antioxidant with antirheumatic properties.
T40655 3,4,5-Trichloroguaiacol

Others Others
3,4,5-Trichloroguaiacol is a phenolic compound that is commonly found in the effluents originating from bleached kraft pulp mills.
T40299 4,5,6-Trichloroguaiacol

Others Others
4,5,6-Trichloroguaiacol is a phenolic compound that is commonly found in the effluents generated by bleached kraft pulp mills.
T19303 (E/Z)-Methyl mycophenolate

Others Others
Methyl mycophenolate can be used to synthesize mycophenolic acid β-D-glucuronide and phenolic glycosides. (E/Z)-Methyl mycophenolate is a racemic compound of (Z)-Methyl mycophenolate and (E)-Methyl mycophenolate isomers. Methyl mycophenolate is a methyl e
T32876 Loquatoside

Others Others
Loquatoside belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position. Loquatoside exists as a solid,
T78453 Fast Blue B Salt

Fast Blue B Salt作为染色剂,能溶解黑麦提取物中的脂肪及苯酚化合物和重氮剂。该化合物能够用于黑麦中的烷基间苯二酚半定量分析,并在加入丙酮的情况下形成有色沉淀。
T69014 Sekikaic Acid

Others Others
Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µM. Sekikaic acid is active against the rg recombinant strain of respiratory syncytial virus (RSV; IC50 = 5.69 µg/ml). It inhibits the protein-protein interaction between mixed lineage leukemia 1 (MLL1) and the GACKIX domain of CREB-binding protein (CBP; IC50 = 34 µM).
T36504 STY-BODIPY

STY-BODIPY,Styrene-BODIPY

STY-BODIPY is a styrene-conjugated fluorogenic probe for radical-trapping antioxidant (RTA) activity.1 Co-autoxidation of the STY-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring the loss of absorbance at 571 nm. STY-BODIPY has been used to measure the activity of RTAs, as well as the kinetics and stoichiometry of RTA reactions in cell-free assays.1,2,3References1. Haidasz, E.A., Van Kessel, A.T.M., and Pratt, D.A. A continuous visible light spectrophotometric...

化合物

VH032-cyclopropane-F
Cat.No: T17877
Synonym: VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101
Target: Others, Ligand for E3 Ligase
Mycophenolic Acid Impurity
Cat.No: T3097
Synonym: 马替麦考酚酸杂质,5,7-dihydroxy-4-methylphthalide
Target: Others
Mycophenolic acid sodium
Cat.No: T61099
Synonym:
Target: Others
Mycophenolic acid IV
Cat.No: T124275
Synonym:
Target: Others
3-Methylindolin-2-one
Cat.No: T0538
Synonym: 3-Methyloxindole,3-Methyl-2-oxindole,3-甲基羟基吲哚
Target: Others, Endogenous Metabolite, AChE
Succinobucol
Cat.No: T4287
Synonym: Probucol monosuccinate,AGI-1067
Target: Antioxidant, Reactive Oxygen Species
2-Chloro-4-nitrophenol
Cat.No: T9443
Synonym:
Target: Others
4-Butoxyphenol
Cat.No: T1350
Synonym: 4-正丁氧基苯酚,P-Butoxyphenol
Target: Others
Fragilin
Cat.No: T31875
Synonym:
Target: Others
2,6-Dibromoquinone-4-chloroimide
Cat.No: T35514
Synonym:
Target:
Leiocarposide
Cat.No: T32625
Synonym: Lejokarpozyd
Target: Others
Dienestrol diacetate
Cat.No: T20764
Synonym: NSC 81279,NSC81279,Cycladiene,Retalon-oral,Oestrasid C,NSC-81279
Target: Others
Lacticolorin
Cat.No: T32528
Synonym:
Target: Others
Salicortin
Cat.No: T12828
Synonym:
Target: NF-κB, JNK
Camobucol
Cat.No: T14861
Synonym: AGIX 4207
Target: Others
3,4,5-Trichloroguaiacol
Cat.No: T40655
Synonym:
Target: Others
4,5,6-Trichloroguaiacol
Cat.No: T40299
Synonym:
Target: Others
(E/Z)-Methyl mycophenolate
Cat.No: T19303
Synonym:
Target: Others
Loquatoside
Cat.No: T32876
Synonym:
Target: Others
Fast Blue B Salt
Cat.No: T78453
Synonym:
Target:
Sekikaic Acid
Cat.No: T69014
Synonym:
Target: Others
STY-BODIPY
Cat.No: T36504
Synonym: STY-BODIPY,Styrene-BODIPY
Target:
Cat. No. Product Name Target Signaling Pathways
T6S0444 Salvianolic acid A

丹酚酸 A,Dan Phenolic Acid A

MMP Proteases/Proteasome
Salvianolic acid A (Dan Phenolic Acid A) 能够提高抑制基质金属钛酶 9 和抗炎作用,进而保护血脑屏障。
T5623 Bisphenol A

Others; Endogenous Metabolite Metabolism; Others
Bisphenol A 是酚类内源性代谢合成物,广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质,常被归类为内分泌干扰物。它与许多疾病有关,包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。
TN6771 Malabaricone B

Others Others
Malabaricone B 是一种源自香料的酚类物质,它通过不依赖 p53 的途径诱导肺癌细胞中的线粒体损伤。
T9933 Methyl 2,4-dihydroxyphenylacetate

Others Others
Methyl 2,4-dihydroxyphenylacetate 是从 Nigella damascena 种子中分离得到的天然产物,具有选择性的植物毒性作用。
T40388 Methyl 5-hydroxypyridine-2-carboxylate

Others Others
Methyl 5-hydroxypyridine-2-carboxylate 是存在于 Mahonia fortune 茎中的一种酚酸,在体外表现出 NO 抑制活性。
T3S1852 Cephaeline hydrochloride

Others; Virus Protease; Influenza Virus Microbiology/Virology; Others
Cephaeline hydrochloride 是 Indian Ipecac 中的一种酚类生物碱。它有效抑制病毒 ZIKV 和 EBOV 感染。
TN1480 Cephaeline

吐根鹼,吐根酚碱

Virus Protease; Influenza Virus; HIF Angiogenesis; Chromatin/Epigenetic; Microbiology/Virology
Cephaeline 对受保护的原代 CLL 细胞具有高度活性(相对 IC50 为 35nM),并通过抑制 HIF-1α± 和扰乱细胞内氧化还原稳态发挥作用。
TN5088 2,6-Dimethoxyphenol

Syringol,2,6-二甲氧基苯酚

Others Others
2,6-Dimethoxyphenol (Syringol) 是一种天然产物,可用于测量漆酶活性。
T4S1820 Parishin

巴利森苷A,派立辛,Parishin A

Others Others
Parishin (Parishin A) A 是一种酚类葡萄糖苷,从天麻中分离得到。Parishin 通过调节 Sir2/Uth1/TOR 信号通路而具有抗衰老作用,并延长酵母寿命。
T26288 Clovamide

trans-Clovamide,N-trans-Caffeoy-L-dopa

Apoptosis; Influenza Virus; ROS; Antibacterial Apoptosis; Immunology/Inflammation; Microbiology/Virology
Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物,具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
T4S0554 Theaflavine-3,3'-digallate

TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素

Others Others
Theaflavine-3,3'-digallate (theaflavin digallate) 和乳酸一起可以减少单纯疱疹病毒的传播。
T9368 3,4-(Methylenedioxy)cinnamic acid

3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid,3,4-(亚甲二氧)肉桂酸

Others Others
3,4-(Methylenedioxy)cinnamic acid (3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid) 是一种植物衍生化合物,首先从芦笋的根中提取,并进一步表征为一种化感化学物质。
T60104 Mycophenolic acid-β-D-glucuronide

Others Others
Mycophenolic acid glucuronide 是人血浆中mycophenolic acid 的葡糖甙代谢产物。
T1335 Mycophenolic acid

霉酚酸,Mycophenolate,RS-61443

Apoptosis; Dehydrogenase; Endogenous Metabolite; Antibacterial; Antibiotic; UGT; Antifungal Apoptosis; Metabolism; Microbiology/Virology
Mycophenolic acid (Mycophenolate) 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂,EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂,具有抗血管生成和抗肿瘤作用。
TN5426 Sonnerphenolic B

(+)-Sonnerphenolic B

Sonnerphenolic B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5426,CAS号为 1627516-10-2。
T4961 9''-Methyl salvianolate B

9'-Methyl lithospermate B,9’-丹酚酸B单甲酯,9''-丹酚酸B单甲酯

Others Others
9'-Methyl lithospermate B 是一种酚类化合物,提取自 RadixSalvia miltiorrhizae。
TN1125 Neonuezhenide

Antioxidant oxidation-reduction
Neonuezhenide 是一种从木犀科植物女贞中分离出来的酚类化合物,对自由基诱导的红血球溶血有较强的抗氧化作用。
T5098 Isochlorogenic acid A

3,5-CQA,异绿原酸 A,3,5-Dicaffeoylquinic acid,金银花

Reactive Oxygen Species; HBV; Endogenous Metabolite Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) 是一种天然酚酸,具有抗氧化和抗炎活性。
TN7248 Torachrysone tetraglucoside

Antioxidant; Antifungal Microbiology/Virology; oxidation-reduction
Torachrysone tetraglucoside 是从豆科植物决明子中分离得到的酚苷,具有抗氧化和抗菌活性。
TN7253 Torachrysone gentiobioside

Torachrysone gentiobioside 是一种从决明子中分离出来的酚苷类化合物。
TMA1603 Parishin C

巴利森苷 C,巴利森苷C

Antioxidant oxidation-reduction
Parishin C 是一种从天麻中分离出的 Parishin 衍生物,可能具有抗氧化作用。
T2861 Tyrosol

4-Hydroxyphenylethanol,2-(4-Hydroxyphenyl)ethanol,4-Hydroxyphenethyl alcohol,酪醇

Antioxidant; NF-κB; Endogenous Metabolite Metabolism; NF-κB; oxidation-reduction
Tyrosol (2-(4-Hydroxyphenyl)ethanol) 是苯乙醇的衍生物。它减弱来自星形胶质细胞的促炎细胞因子,抑制NF-κB 活化,具有抗炎和抗氧化的作用。
TQ0054 Purpureaside C

Others Others
Purpureaside C 是一种酚类糖苷类,具有显着的促炎、免疫调节和抗菌作用。
TN7025 Canolol

菜籽多酚,Phenol, 4-ethenyl-2,6-dimethoxy-

COX Immunology/Inflammation; Neuroscience
Canolol (Phenol, 4-ethenyl-2,6-dimethoxy-) 是一种抗氧化酚类化合物,可用作 COX-2 抑制剂。
T2215 Ferulic Acid

Coniferic acid,Fumalic Acid,阿魏酸

FGFR; Endogenous Metabolite Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
Ferulic Acid (Coniferic acid) 是新型的成纤维细胞生长因子受体 1 (FGFR1)抑制剂, 在FGFR1和FGFR2的IC50分别为 3.78 和 12.5 μM。
TN1166 1,3,6-Tri-O-galloyl-beta-D-glucose

1,3,6-三没食子酰葡萄糖,1,3,6-Tri-O-galloyl-β-D-glucose,1,3,6-Tri-O-galloylglucose,1,3,6-三-O-3,4,5-三羟基苯甲酰-BETA-D-葡萄糖

Immunology/Inflammation related Immunology/Inflammation
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) 是一种酚类化合物,分离自Black Walnut Kernels 中。
T8163 Glucovanillin

葡萄糖香草醛,Vanillin 4-O-β-D-Glucoside,4-(β-D-葡萄糖氧基)-3-甲氧基苯甲醛

Others Others
Glucovanillin (Vanillin 4-O-β-D-Glucoside) 是提取于青荚中,通过细胞壁降解和葡萄糖酐水解的酶联合作用可转化为香草醛。
T1516 Curcumin

Diferuloylmethane,Natural Yellow 3,姜黄素,Indian Saffron,Turmeric yellow

Mitophagy; Epigenetic Reader Domain; Ferroptosis; Influenza Virus; Nrf2; Histone Acetyltransferase; HDAC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology
Curcumin (Natural Yellow 3) 属于酚类天然产物,是一种组蛋白乙酰化转移酶 p300/CREB 的抑制剂 (IC50=25 μM),具有特异性。Curcumin 具有抗肿瘤、抗炎和抗氧化等多种药理活性。
TN2130 Manghaslin

槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

AChE; Glucosidase Metabolism; Neuroscience
Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) 是具有抗炎活性的黄酮苷,对 AChE 具有抑制活性,IC50=94.92 µM。
TCS1856 2'-Hydroxyacetophenone

2'-羟基苯乙酮,o-Hydroxyacetophenone,o-Acetylphenol,2-Acetylphenol,O-Hydroxyphenyl Methyl Ketone

CYP19A1 Others
2'-Hydroxyacetophenone (o-Hydroxyacetophenone) 是有机合成中的砌块,存在于番茄,决明子,炒牛肉,朗姆酒,威士忌,可可,咖啡和红茶中。它是调味成分,存在于酒精饮料中。
T2784 Ethyl Orsellinate

苷色酸乙酯,山梨酸乙酯,Orsellinic acid ethyl ester

Others; Antibacterial Microbiology/Virology; Others
Ethyl Orsellinate (Orsellinic acid ethyl ester) 是地衣代谢产物,抑制A.salina 的细胞毒性活性,IC50为 495 μM。它是 lecanoric acid 的衍生物,具有抗增殖和抗肿瘤活性。
T0657 Veratryl alcohol

3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇

Others Others
3,4-Dimethoxybenzyl alcohol 是木质素降解真菌的次级代谢产物,通常作为非酚性底物测定木质素分解活性。Veratryl alcohol 保护木质素过氧化物酶 (LiP) 避免因为 H2O2 而失活并且防止 LiP III 化合物的累积[3]
TN2719 2',4'-Dihydroxy-6'-methoxyacetophenone

Antibacterial Microbiology/Virology
2',4'-Dihydroxy-6'-methoxyacetophenone 是从豆科植物和菊科植物中提取的酚类苯乙酮,具有抗菌活性,可用于合成吡喃镰酮。
Fr14298 2'-Hydroxy-4'-methylacetophenone

2'-羟基-4'-甲基苯乙酮,2′-羟基-4′-甲基苯乙酮

Anti-infection Microbiology/Virology
2'-Hydroxy-4'-methylacetophenone 是一种分离自韩国当归根部得到的酚类,可用于合成 4’-methyl-2’-[(p-tolylsulfonyl) oxy] acetophenone,具有杀螨作用。
TN7231 Di-O-methylhonokiol

Honokiol dimethyl ether

Antioxidant oxidation-reduction
Di-O-methylhonokiol (Honokiol dimethyl ether) 是Magnolia grandiflora L 的酚类成分,具有抗微生物活性,对革兰氏阳性和抗酸细菌和真菌具有显著的抗氧化活性。
T5528 Cyanidin Chloride

Antioxidant oxidation-reduction
Cyanidin Chloride 是一种花青素的亚类,具有抗氧化和抗癌活性。它能够抑制破骨细胞形成,羟基磷灰石吸收和 NF-κB 配体 (RANKL) 诱导的破骨细胞标记基因表达的受体激活。
T7910 4-Methoxybenzaldehyde

大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde

Others; Endogenous Metabolite Metabolism; Others
4-Methoxybenzaldehyde (p-Anisaldehyde) 是一种天然存在的芳香酚类化合物,存在于许多植物物种中,包括辣根,茴香,八角茴香等。它是一种能够能的神经毒物,已经表现出致死亡率,吸引力和干扰宿主寻求的影响。
T2805 Chlorogenic Acid

NSC-407296,3-O-Caffeoylquinic acid,Heriguard,绿原酸

Others; Influenza Virus; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite; Antibacterial Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others
Chlorogenic acid 作为金银花中的主要酚类化合物,具有潜在的抗氧化,抗菌抗炎和抗癌活性,可用于晚期癌症和葡萄糖耐量受损治疗等相关研究。
T5592 Acetosyringone

乙酰丁香酮,Acetosyringenin

Others Others
Acetosyringone (Acetosyringenin) 是一种从受伤的植物细胞中产生的酚类化合物。virA 基因能够编码膜结合蛋白,感知 Acetosyringone,使自身磷酸化并激活 vir 基因产物,后者刺激自身及其他 vir 基因的转录。它可提高 Agrobacterium 介导的杜氏盐藻的高效转化。
T2717 Salidroside

红景天苷,Rhodioloside

Apoptosis; mTOR Apoptosis; PI3K/Akt/mTOR signaling
Salidroside (Rhodioloside) 是一种从红景天中分离出来的具有生物活性的酚苷化合物,是一种脯氨酰内肽酶抑制剂。它能通过激活 mTOR 信号缓解肿瘤恶病质小鼠模型中的恶病质症状,还能通过增强 PINK1/Parkin 介导的线粒体自噬来保护多巴胺能神经元。
T7113 Paradol

姜酮酚,6-paradol,必理通,[6]-Gingerone

COX Immunology/Inflammation; Neuroscience
Paradol ([6]-Gingerone) 是一种姜科植物中发现的酚类天然产物,具有抗癌、抗炎、抗氧化和神经保护作用。在小鼠皮肤癌变中,可结合到环氧合酶(COX-2) 活性位点。
T20578 Maclurin

Fustic extract,Morintannic acid,NSC 83240

Free radical scavengers; Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
Maclurin (NSC-83240) 是桑枝的酚类成分,具有抗转移作用。 Maclurin 可有效防止 OH 诱导的 DNA 和 MSCs 损伤,可用于预防多种疾病或 MSCs 移植的研究。
T2989 4-Hydroxybenzoic acid

p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate

Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology
4-Hydroxybenzoic acid (4-hydroxybenzoate) 是苯甲酸的酚衍生物,可抑制革兰氏阳性和革兰氏阴性菌,IC50值为160 μg/mL。
TQ0269 Melittoside

蜜力特苷,美利妥双甙

Antioxidant oxidation-reduction
Melittoside 是一种天然酚苷,存在于梅利藤属的花蜜中。它具有抗氧化、抗炎和抗真菌的活性,以及研究了它在治疗各种疾病中的潜在用途,包括癌症、糖尿病和心血管疾病。
T4815 Hippuric acid

马尿酸,2-Benzamidoacetic acid,Benzoylglycine

Others; Endogenous Metabolite Metabolism; Others
Hippuric acid (2-Benzamidoacetic acid) 是一种正常的尿液成分,是苯酸和甘氨酸结合作用下产生的一种酰基甘氨酸,来自食物的芳香化合物的代谢。
TJS2190 Nordihydroguaiaretic acid

去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid

Antioxidant; Ferroptosis; Lipoxygenase; Autophagy Apoptosis; Autophagy; Metabolism; oxidation-reduction
Nordihydroguaiaretic acid (NDGA) 是从极叉开拉瑞阿提取出的一种天然产物,是脂氧合酶抑制剂,具有抗氧化和清除自由基的特性。
T0562 Protocatechuic acid

3, 4-Dihydroxybenzoic acid,3,4-二羟基苯甲酸,Protocatechuate,原儿茶酸,3,4-Dihydroxybenzoic acid

Others Others
Protocatechuic acid (3, 4-Dihydroxybenzoic acid) 是天然的多酚类物质,具有神经保护活性。
TN1950 Moracin M

PDE Metabolism
Moracin M 是桑白皮中的一种酚类成分,有效的磷酸二酯酶 4 (PDE4) 抑制剂,对于 PDE4D2,PDE4B2,PDE5A1 和 PDE9A2 的 IC50 分别为 2.9 μM,4.5 μM,> 40 μM 和 > 100 μM。Moracin M 具有抗炎活性。
TN6551 Tectoruside

Antioxidant oxidation-reduction
Tectoruside 是一种从鸢尾和豹纹百合中提取得到的酚酸糖苷,具有抗诱变和抗氧化活性,通过靶向ROS相关炎症和IRS-1通路来减弱棕榈酸酯诱导的内皮胰岛素抵抗。Tectoruside 可用于研究癌症。
T3392 Sinapine thiocyanate

P-gp; AChE Membrane transporter/Ion channel; Neuroscience
Sinapine thiocyanate 是萝卜中分离出来的一种生物碱,具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂,可用于研究阿尔茨海默症,共济失调,重症肌无力和帕金森氏病。
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天然产物

Salvianolic acid A
Cat.No: T6S0444
Synonym: 丹酚酸 A,Dan Phenolic Acid A
Target: MMP
Bisphenol A
Cat.No: T5623
Synonym:
Target: Others, Endogenous Metabolite
Malabaricone B
Cat.No: TN6771
Synonym:
Target: Others
Methyl 2,4-dihydroxyphenylacetate
Cat.No: T9933
Synonym:
Target: Others
Methyl 5-hydroxypyridine-2-carboxylate
Cat.No: T40388
Synonym:
Target: Others
Cephaeline hydrochloride
Cat.No: T3S1852
Synonym:
Target: Others, Virus Protease, Influenza Virus
Cephaeline
Cat.No: TN1480
Synonym: 吐根鹼,吐根酚碱
Target: Virus Protease, Influenza Virus, HIF
2,6-Dimethoxyphenol
Cat.No: TN5088
Synonym: Syringol,2,6-二甲氧基苯酚
Target: Others
Parishin
Cat.No: T4S1820
Synonym: 巴利森苷A,派立辛,Parishin A
Target: Others
Clovamide
Cat.No: T26288
Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa
Target: Apoptosis, Influenza Virus, ROS, Antibacterial
Theaflavine-3,3'-digallate
Cat.No: T4S0554
Synonym: TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素
Target: Others
3,4-(Methylenedioxy)cinnamic acid
Cat.No: T9368
Synonym: 3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid,3,4-(亚甲二氧)肉桂酸
Target: Others
Mycophenolic acid-β-D-glucuronide
Cat.No: T60104
Synonym:
Target: Others
Mycophenolic acid
Cat.No: T1335
Synonym: 霉酚酸,Mycophenolate,RS-61443
Target: Apoptosis, Dehydrogenase, Endogenous Metabolite, Antibacterial, Antibiotic, UGT, Antifungal
Sonnerphenolic B
Cat.No: TN5426
Synonym: (+)-Sonnerphenolic B
Target:
9''-Methyl salvianolate B
Cat.No: T4961
Synonym: 9'-Methyl lithospermate B,9’-丹酚酸B单甲酯,9''-丹酚酸B单甲酯
Target: Others
Neonuezhenide
Cat.No: TN1125
Synonym:
Target: Antioxidant
Isochlorogenic acid A
Cat.No: T5098
Synonym: 3,5-CQA,异绿原酸 A,3,5-Dicaffeoylquinic acid,金银花
Target: Reactive Oxygen Species, HBV, Endogenous Metabolite
Torachrysone tetraglucoside
Cat.No: TN7248
Synonym:
Target: Antioxidant, Antifungal
Torachrysone gentiobioside
Cat.No: TN7253
Synonym:
Target:
Parishin C
Cat.No: TMA1603
Synonym: 巴利森苷 C,巴利森苷C
Target: Antioxidant
Tyrosol
Cat.No: T2861
Synonym: 4-Hydroxyphenylethanol,2-(4-Hydroxyphenyl)ethanol,4-Hydroxyphenethyl alcohol,酪醇
Target: Antioxidant, NF-κB, Endogenous Metabolite
Purpureaside C
Cat.No: TQ0054
Synonym:
Target: Others
Canolol
Cat.No: TN7025
Synonym: 菜籽多酚,Phenol, 4-ethenyl-2,6-dimethoxy-
Target: COX
Ferulic Acid
Cat.No: T2215
Synonym: Coniferic acid,Fumalic Acid,阿魏酸
Target: FGFR, Endogenous Metabolite
1,3,6-Tri-O-galloyl-beta-D-glucose
Cat.No: TN1166
Synonym: 1,3,6-三没食子酰葡萄糖,1,3,6-Tri-O-galloyl-β-D-glucose,1,3,6-Tri-O-galloylglucose,1,3,6-三-O-3,4,5-三羟基苯甲酰-BETA-D-葡萄糖
Target: Immunology/Inflammation related
Glucovanillin
Cat.No: T8163
Synonym: 葡萄糖香草醛,Vanillin 4-O-β-D-Glucoside,4-(β-D-葡萄糖氧基)-3-甲氧基苯甲醛
Target: Others
Curcumin
Cat.No: T1516
Synonym: Diferuloylmethane,Natural Yellow 3,姜黄素,Indian Saffron,Turmeric yellow
Target: Mitophagy, Epigenetic Reader Domain, Ferroptosis, Influenza Virus, Nrf2, Histone Acetyltransferase, HDAC, Autophagy
Manghaslin
Cat.No: TN2130
Synonym: 槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside
Target: AChE, Glucosidase
2'-Hydroxyacetophenone
Cat.No: TCS1856
Synonym: 2'-羟基苯乙酮,o-Hydroxyacetophenone,o-Acetylphenol,2-Acetylphenol,O-Hydroxyphenyl Methyl Ketone
Target: CYP19A1
Ethyl Orsellinate
Cat.No: T2784
Synonym: 苷色酸乙酯,山梨酸乙酯,Orsellinic acid ethyl ester
Target: Others, Antibacterial
Veratryl alcohol
Cat.No: T0657
Synonym: 3,4-Dimethoxybenzyl alcohol,藜芦醇,3,4-二甲氧基苄醇
Target: Others
2',4'-Dihydroxy-6'-methoxyacetophenone
Cat.No: TN2719
Synonym:
Target: Antibacterial
2'-Hydroxy-4'-methylacetophenone
Cat.No: Fr14298
Synonym: 2'-羟基-4'-甲基苯乙酮,2′-羟基-4′-甲基苯乙酮
Target: Anti-infection
Di-O-methylhonokiol
Cat.No: TN7231
Synonym: Honokiol dimethyl ether
Target: Antioxidant
Cyanidin Chloride
Cat.No: T5528
Synonym:
Target: Antioxidant
4-Methoxybenzaldehyde
Cat.No: T7910
Synonym: 大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde
Target: Others, Endogenous Metabolite
Chlorogenic Acid
Cat.No: T2805
Synonym: NSC-407296,3-O-Caffeoylquinic acid,Heriguard,绿原酸
Target: Others, Influenza Virus, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Antibacterial
Acetosyringone
Cat.No: T5592
Synonym: 乙酰丁香酮,Acetosyringenin
Target: Others
Salidroside
Cat.No: T2717
Synonym: 红景天苷,Rhodioloside
Target: Apoptosis, mTOR
Paradol
Cat.No: T7113
Synonym: 姜酮酚,6-paradol,必理通,[6]-Gingerone
Target: COX
Maclurin
Cat.No: T20578
Synonym: Fustic extract,Morintannic acid,NSC 83240
Target: Free radical scavengers, Reactive Oxygen Species
4-Hydroxybenzoic acid
Cat.No: T2989
Synonym: p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate
Target: Endogenous Metabolite, Antibacterial
Melittoside
Cat.No: TQ0269
Synonym: 蜜力特苷,美利妥双甙
Target: Antioxidant
Hippuric acid
Cat.No: T4815
Synonym: 马尿酸,2-Benzamidoacetic acid,Benzoylglycine
Target: Others, Endogenous Metabolite
Nordihydroguaiaretic acid
Cat.No: TJS2190
Synonym: 去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid
Target: Antioxidant, Ferroptosis, Lipoxygenase, Autophagy
Protocatechuic acid
Cat.No: T0562
Synonym: 3, 4-Dihydroxybenzoic acid,3,4-二羟基苯甲酸,Protocatechuate,原儿茶酸,3,4-Dihydroxybenzoic acid
Target: Others
Moracin M
Cat.No: TN1950
Synonym:
Target: PDE
Tectoruside
Cat.No: TN6551
Synonym:
Target: Antioxidant
Sinapine thiocyanate
Cat.No: T3392
Synonym:
Target: P-gp, AChE
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Cat. No. Product Name Species Expression System
TMPY-02062 SULT1A1 Protein, Human, Recombinant (His)

HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotransferase family, cyt...

Human E. coli
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa...
TMPY-02948 SULT1A3 Protein, Human, Recombinant (His)

M-PST,HAST,SULT1A3,ST1A3/ST1A4,HAST3,SULT1A4,TL-PST,STM,sulf...

Human E. coli
SULT1A3 belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. They are different in their tissue distributions and substrate specificities while their gene structure (number and length of exons) is similar. SULT1A3 gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 ar...
TMPY-03414 ABHD10 Protein, Human, Recombinant (aa 53-306, His)

ABHD10,abhydrolase domain containing 10

Human Baculovirus Insect Cells
Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil (MMF), is primarily metabolized by glucuronidation to a phenolic glucuronide (MPAG) and an acyl glucuronide (AcMPAG). It is known that AcMPAG, which may be an immunotoxic metabolite, is deglucuronidated in human liver. AcMPAG deglucuronidation activity was detected in both human liver cytosol (HLC) and microsomes (HLM). By purification from HLC with column chromatographic purification steps, the en...

重组蛋白

SULT1A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02062
Species: Human
Expression System: E. coli
SULT1A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02948
Species: Human
Expression System: E. coli
ABHD10 Protein, Human, Recombinant (aa 53-306, His)
Cat.No: TMPY-03414
Species: Human
Expression System: Baculovirus Insect Cells
Cat. No. Product Name Target Signaling Pathways
T12445 Phenolic acid

Others Others
Phenolic acid is an endogenous metabolite.
TMIH-0359 Mycophenolic Acid-d3 Phenyl Glucuronide

Mycophenolic Acid-d3 Phenyl Glucuronide 是 Mycophenolic Acid Phenyl Glucuronide 的氘代化合物。Mycophenolic Acid Phenyl Glucuronide 的 CAS 号为 31528-44-6。Mycophenolic acid glucuronide是人血浆中mycophenolic acid的葡糖甙代谢产物。
T12135 Mycophenolic acid-d3

Mycophenolate-d3,Mycophenolate D3

Others; Antibacterial Microbiology/Virology; Others
Mycophenolic acid-d3 (Mycophenolate-d3) 是 Mycophenolic acid 的衍生物。Mycophenolic acid 是一种降低GTP 水平和损害RNA 聚合酶II (RNAP II)转录延伸的化合物,促进了近端位点的使用,能够逆转虫草素对选择性聚腺苷化的作用。
TMIJ-0087 Mycophenolic acid-13C-d3

Mycophenolic acid-13C-d3 是 Mycophenolic acid 的 13C 和氘代化合物。Mycophenolic acid 的 CAS 号为 24280-93-1。Mycophenolic acid 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂,EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂,具有抗血管生成和抗肿瘤作用。
T10901 Curcumin-d6

Turmeric yellow D6,Natural Yellow 3 D6,Curcumin D6,Diferuloylmethane D6

Others Others
Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-a
TMIJ-0041 Hippuric Acid-d5

Hippuric Acid-d5 是 Hippuric Acid 的氘代化合物。Hippuric Acid 的 CAS 号为 495-69-2。Hippuric Acid 是一种正常的尿液成分,是苯酸和甘氨酸结合作用下产生的一种酰基甘氨酸,来自食物的芳香化合物的代谢。

同位素标记化合物

Phenolic acid
Cat.No: T12445
Synonym:
Target: Others
Mycophenolic Acid-d3 Phenyl Glucuronide
Cat.No: TMIH-0359
Synonym:
Target:
Mycophenolic acid-d3
Cat.No: T12135
Synonym: Mycophenolate-d3,Mycophenolate D3
Target: Others, Antibacterial
Mycophenolic acid-13C-d3
Cat.No: TMIJ-0087
Synonym:
Target:
Curcumin-d6
Cat.No: T10901
Synonym: Turmeric yellow D6,Natural Yellow 3 D6,Curcumin D6,Diferuloylmethane D6
Target: Others
Hippuric Acid-d5
Cat.No: TMIJ-0041
Synonym:
Target:
TargetMol Loading
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