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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19679 |
Benoxaprofen
氧苯恶唑丙酸,NSC 299582,LY-90459,Benoxaphen. Compound 90459 |
COX | Immunology/Inflammation; Neuroscience |
Benoxaprofen (NSC-299582) 是长效的、强效的抗炎和解热化合物,在体外具有较弱的对环氧合酶的抑制作用,也可以抑制脂氧合酶,在一些炎症动物模型中抑制单核细胞迁移。 | |||
T27604 |
INCB-9471 HCl
INCB 9471,INCB-9471,INCB9471,INCB-009471,INCB 009471,INCB009471 |
Others | Others |
INCB-9471 HCl, an allosteric noncompetitive small-molecule antagonist of C-C chemokine receptor 5, has potent inhibitory activity against monocyte migration and HIV-1 infection. | |||
T36052 |
Lipoxin A4 methyl ester
LXA4 methyl ester |
Others | Others |
Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM.[2] LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00952 |
SDF-1/CXCL12 Protein, Mouse, Recombinant
Sdf1,C-X-C motif chemokine 12,Thymic lymphoma cell-stimulati... |
Mouse | E. coli |
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, and lymphoid organs. Cxcl12 activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. It also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scaven... |