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Targets Recommended: MMP

58

抑制剂 & 化合物

29

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18

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Cat. No. Product Name Target Signaling Pathways
T8961 GW280264X

Carbamic acid

MMP Proteases/Proteasome
GW280264X (Carbamic acid) 是一种 ADAM10/TACE (ADAM17)金属蛋白酶抑制剂。它有效阻断 TACE (ADAM17)和 ADAM10的 IC50分别为 8.0 nM 和 11.5 nM。其中ADAM10/17 能够调节胶质母细胞瘤起始细胞的免疫原性。
T5361 T-26c

MMP Proteases/Proteasome
T-26c 是高效的、选择性的基质金属蛋白酶-13 抑制剂,IC50=6.75 pM。
T14978 CL-82198

MMP Proteases/Proteasome
CL-82198 是 MMP-13选择性抑制剂。它能够与 MMP-13 的整个 S1' 口袋结合,这是其对 MMP-13 选择性和对其他 MMP 缺乏抑制活性的基础。它可用于研究骨关节炎。
T4783 JNJ0966

MMP Proteases/Proteasome
JNJ0966 是高选择性 MMP-9酶原抑制剂,其 IC50=440 nM。
T16966 S 3304

MMP Proteases/Proteasome
S 3304 是一种新型的基质金属蛋白酶抑制剂,能够特异的抑制MMP-2和MMP-9的活性。
T16124 MMP13-IN-3

MMP Proteases/Proteasome
MMP13-IN-3 是口服有效的MMP-13选择性抑制剂,IC50为 1 nM,比其他 MMP 的选择性高 1000倍多。MMP13-IN-3在用于骨关节炎方面有研究的价值。
T5416 T-5224

MMP Proteases/Proteasome
T-5224 是选择性的转录因子c-Fos/activator protein (AP)-1抑制剂,具有抗炎作用,能够特异性抑制 c-Fos/c-Jun 的 DNA 结合活性,但对其他转录因子的结合活性无影响。它抑制 IL-1β 诱导的 Mmp-3、Mmp-13、Adamts-5 转录上调。
T5983 o-Phenanthroline

1,10-菲罗啉,1,10-Phenanthroline

MMP; Others Others; Proteases/Proteasome
o-Phenanthroline (1,10-Phenanthroline) 是一种金属螯合剂,能够与 Fe2+形成红色螯合物,在 510 nm 处最大吸收,可防止链脲佐菌素诱导染色体畸变。它也是一种MMP 的抑制剂。
T6011 Batimastat

巴马司他,BB94

MMP Proteases/Proteasome
Batimastat (BB94) 是广谱MMP 抑制剂,能够抑制MMP-1 (IC50:3 nM),MMP-2 (IC50:4 nM),MMP-9 (IC50:4 nM),MMP-7 (IC50:6 nM) 和 MMP-3 (IC50:20 nM)。
T7522 GI254023X

GI 254023X

MMP; Immunology/Inflammation related Immunology/Inflammation; Proteases/Proteasome
GI254023X 是MMP9和ADAM10抑制剂,它们的IC50s 分别为 2.5 和 5.3 nM。
T1891 NSC 405020

MMP Proteases/Proteasome
NSC 405020 是一种 MT1-MMP 的非催化抑制剂,可特异地靶向 MT1-MMP 的 PEX 结构域,不会抑制 MT1-MMP 和 MMP-2的催化活性。
T8310 MMP-9-IN-1

MMP Proteases/Proteasome
MMP-9-IN-1 是特异性的基质金属蛋白酶-9 抑制剂,选择性靶向 MMP-9 的血红素域,对其他 MMP 无影响。
T2743 Ilomastat

Galardin,GM6001,伊洛马司他

MMP Proteases/Proteasome
Ilomastat (GM6001) 是广谱的基质金属蛋白酶 (MMP) 抑制剂,可抑制 MMP 的活性,IC50值分别为 1.5 nM (MMP-1),1.1 nM (MMP-2),1.9 nM (MMP-3),0.5 nM (MMP-9),对人皮肤成纤维细胞胶原酶 (MMP-1) 的Ki=为 0.4 nM。
T4282 S-methyl-KE-298

MMP; Drug Metabolite Metabolism; Proteases/Proteasome
S-methyl-KE-298 是 KE-298 的活性代谢物。KE-298 抑制类风湿关节炎滑膜细胞产生基质金属蛋白酶。
T2009 SB-3CT

MMP Proteases/Proteasome
SB-3CT 是一种可透过血脑屏障的、竞争性的金属蛋白酶MMP-2和MMP-9抑制剂,Ki 分别为 13.9 nM、600 nM。他对明胶酶具有高选择性。它具有神经保护和抗癌作用。
T21806 HNHA

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
HNHA 是组蛋白去乙酰化酶抑制剂。它通过 p21诱导将细胞周期阻滞在 G1/S 期,抑制肿瘤生长及肿瘤新生血管形成。HNHA 可能是一种有效的抗乳腺癌药物。
T0407 Edaravone

依达拉奉右莰醇,依达拉奉,MCI-186

Apoptosis; MMP; Free radical scavengers Apoptosis; oxidation-reduction; Proteases/Proteasome
Edaravone (MCI-186) 是一种新型自由基清除剂,能够抑制大鼠与 MMP-9有关的脑出血。
T15574 Incyclinide

COL-3,CMT-3

MMP Proteases/Proteasome
Incyclinide (COL-3) 是一种基质金属蛋白酶 (MMP) 抑制剂,能够诱导细胞外基质降解,抑制血管生成,肿瘤生长和侵袭以及转移。
T22115 SM-7368

NF-κB NF-κB
NF-κB Activation Inhibitor III 是一种NF-kB 抑制剂,抑制 TNF-α 诱导的MMP-9上调,靶向抑制下游的MAPK p38,可用于靶向 TNF-α 介导的肿瘤侵袭和转移的化疗研究。
T14322 ARP-100

MMP-2 Inhibitor III

MMP Proteases/Proteasome
ARP-100 (MMP-2 Inhibitor III) 是选择性基质金属蛋白酶MMP-2抑制剂 (IC50=12 nM)。它对 MMP-1 (>50 μM),MMP-3 (4.5 μM),MMP-7 (>50 μM) 和MMP-9 (0.2 μM) 的抑制活性较小。它与 MMP-2 的 S1'口袋相互作用,并在体外对基质胶的侵袭模型中显示抗侵袭特性。
T1140 Doxycycline hydrochloride

Doxylin,盐酸多西环素,Vibramycin,Hyclate

MMP; Antibacterial; Antibiotic Microbiology/Virology; Proteases/Proteasome
Doxycycline hydrochloride (Hyclate) 是一种四环素抗生素,是口服有效的广谱金属蛋白酶抑制剂,具有抗菌活性。
T7459 Abametapir

5 5'-二甲基-2,2-联吡啶,HA-44,BRN 0123183

MMP; Others; Parasite Microbiology/Virology; Others; Proteases/Proteasome
Abametapir (BRN 0123183) 是一种金属蛋白酶抑制剂,能够靶向对卵孵化和虱子发育至关重要的金属蛋白酶。
T7449 o-Phenanthroline monohydrate

Phenanthroline monohydrate,1, 10-Phenanthroline monohydrate,邻菲罗啉

MMP Proteases/Proteasome
o-Phenanthroline monohydrate (1, 10-Phenanthroline monohydrate) 是一种金属螯合剂,能够与 Fe2+形成红色螯合物,λmax为 510 nm,可防止链脲佐菌素诱导染色体畸变。它也是一种 MMP 的抑制剂。
T6885 Marimastat

BB2516,马立马司他,KB-R8898,TA2516

MMP Proteases/Proteasome
Marimastat (BB2516) 是一种血管生成和转移抑制剂,限制血管的生长和生成。它是一种广谱的,具有口服活性的MMPs 抑制剂,有效抑制 MMP-9 , MMP-1, MMP-2, MMP-14, MMP-7,用于癌症的研究。
T6542 Imidapril hydrochloride

Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366

RAAS Endocrinology/Hormones
Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂,具有抗高血压活性。
T5863 Indinavir sulfate

L735524 sulfate,MK-639 sulfate,硫酸茚地那韦

SARS-CoV; HIV Protease Microbiology/Virology; Proteases/Proteasome
Indinavir sulfate (L735524 sulfate) 是一种 HIV 蛋白酶抑制剂。它抑制 HIV-1 蛋白酶,IC50 值为 0.41 nM,Ki 值为 0.24 nM。它也是SARS-CoV 3CLpro 抑制剂,IC50为 1.71 μM。
T6009 TAPI1

TAPI 1,TAPI,TAPI-1

MMP Proteases/Proteasome
TAPI1 (TAPI) 是一种 ADAM17/TACE 抑制剂,可抑制细胞因子受体的脱落。
TD0056 JC-10

MMP Proteases/Proteasome
JC-10 是一种有效的金属蛋白酶抑制剂,常当作探针使用。
T12539L Prinomastat

KB-R9896,AG3340

MMP Proteases/Proteasome
Prinomastat (AG3340) 是一种可穿过血脑屏障且具有口服活性和选择性的金属蛋白酶 (MMP) 抑制剂,抗肿瘤活性,对金属蛋白酶具有广谱的抑制作用,对 MMP-1, MMP-3 和 MMP-9 的抑制作用较强。
TP1741L Histatin 5 acetate

Histatin 5 acetate (115966-68-2 Free base)

MMP Proteases/Proteasome
Histatin 5 acetate 抑制宿主基质金属蛋白酶 MMP-2 和 MMP-9 的活性,IC50 分别为 0.57 和 0.25 μM。
T61271 MMP2-IN-3

MMP Proteases/Proteasome
MMP2-IN-3是一种有效的基质金属蛋白酶(MMP-2)抑制剂( IC50 值:31 μM)。MMP2-IN-3 抑制 MMP-9 和 MMP-8 ,其 IC50 分别为 26.6 和 32 μM。
TP1501L CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)

MMP Proteases/Proteasome
CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base) 是基质金属蛋白酶 (MMP)-2 和 MMP-9 的抑制剂。它也被称为IV 型胶原酶或明胶酶。明胶酶是癌症治疗干预的潜在靶点,这些酶的抑制剂可以防止肿瘤进展。
T26104 Ro 28-2653

Ro 28 2653,Ro-28-2653,Ro282653

Others Others
Ro 28-2653 is a matrix-metalloproteinases (MMPs) inhibitor with high selectivity for MMP2, MMP9 and membrane type 1-MMP.
T24431 Matlystatin A

Others Others
Matlystatin A is an inhibitor of aminopeptidase. It shows multiple inhibitory activities against both aminopeptidase N and matrix metalloproteinases.
T69503 ABT-518

Others Others
ABT-518 is an inhibitor of matrix metalloproteinases, which are associated with tumor growth and development of metastasis.
T25055 alpha-RA-F

α RA F,alphaRAF,α-RA-F,αRAF

Others Others
alpha-RA-F can modulate collagen synthesis and matrix metalloproteinases (MMPs) expression levels by boosting collagen synthesis and reducing MMPs expression levels in human fibroblasts without cytotoxicity.
T16986 Tanomastat

BAY 12-9566

MMP Proteases/Proteasome
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively.
T13358 XL-784

MMP Proteases/Proteasome
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T70052 S-3304

Others Others
S-3304 is a n orally-agent agent with potential antineoplastic activity. S-3304 inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
T27507 GW-3333

GW 3333,GW3333

Others Others
GW-3333 is an matrix metalloproteinase inhibitor. It is also a tumor necrosis factor-alpha (TNF)-Converting Enzyme (TACE) inhibitor. The efficacy of GW3333 suggests that dual inhibitors of matrix metalloproteinases and TACE may prove therapeutic as antiar
T13357 XL-784 free base

Others Others
XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP), (IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T75755 Histatin 5 TFA

Histatin 5 TFA 抑制宿主基质金属蛋白酶MMP-2和MMP-9活性,IC50s 分别为 0.57 和 0.25 μM。
TP1741 Histatin 5

Histatin 5 inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. Histatin 5 is a human basic salivary peptide with strong fungicidal properties in vitro.
T81728 Myristoyl tetrapeptide Ala-Ala-Pro-Val

Myristoyl tetrapeptide Ala-Ala-Pro-Val 是具有生物活性的四肽,能够促进ECM蛋白的表达以及抑制金属蛋白酶(MMP)的表达。
TP1501 CTTHWGFTLC, CYCLIC

This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of t
TP1446 Histatin 5 (TFA)(115966-68-2,free)

Histatin 5 (TFA)

MMP Proteases/Proteasome
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) 抑制宿主基质金属蛋白酶 MMP-2 和 MMP-9 的活性,IC50 分别为 0.57 和 0.25 μM。
T14312 Apratastat

MMP; TNF Apoptosis; Proteases/Proteasome
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1].
T76017 CTTHWGFTLC, CYCLIC TFA

CTTHWGFTLC, CYCLIC TFA 是一种基质金属蛋白酶 MMP-2和MMP-9的环肽抑制剂。对MMP-9的IC50约为 8 μM。
T71420 RO314724

Others Others
RO314724 is a HDAC inhibitor. RO314724 is also a a reversible, tightly binding, MMP inhibitor with a Ki of 26 nm. Matrix metalloproteinases (MMPs) belong to the key enzymes of the proteolytic destruction of cartilage matrix during chronic rheumatic diseases. Ro314724 displayed MMP-proteoglycanase inhibitory activity both in vitro and ex vivo and proved to be not harmful to the morphology, viability and proteoglycan biosynthesis of bovine articular cartilage explants.
T21735 NNGH

Others Others
NNGH 是基质分解素-1 (MMP-3) 抑制剂。 MMP-3 既是直接转录靶蛋白,也是 Wnt/β-catenin 信号通路的必要组成。 基质金属蛋白酶 (MMP) 在肿瘤进展的晚期发挥着明确的作用。

化合物

GW280264X
Cat.No: T8961
Synonym: Carbamic acid
Target: MMP
T-26c
Cat.No: T5361
Synonym:
Target: MMP
CL-82198
Cat.No: T14978
Synonym:
Target: MMP
JNJ0966
Cat.No: T4783
Synonym:
Target: MMP
S 3304
Cat.No: T16966
Synonym:
Target: MMP
MMP13-IN-3
Cat.No: T16124
Synonym:
Target: MMP
T-5224
Cat.No: T5416
Synonym:
Target: MMP
o-Phenanthroline
Cat.No: T5983
Synonym: 1,10-菲罗啉,1,10-Phenanthroline
Target: MMP, Others
Batimastat
Cat.No: T6011
Synonym: 巴马司他,BB94
Target: MMP
GI254023X
Cat.No: T7522
Synonym: GI 254023X
Target: MMP, Immunology/Inflammation related
NSC 405020
Cat.No: T1891
Synonym:
Target: MMP
MMP-9-IN-1
Cat.No: T8310
Synonym:
Target: MMP
Ilomastat
Cat.No: T2743
Synonym: Galardin,GM6001,伊洛马司他
Target: MMP
S-methyl-KE-298
Cat.No: T4282
Synonym:
Target: MMP, Drug Metabolite
SB-3CT
Cat.No: T2009
Synonym:
Target: MMP
HNHA
Cat.No: T21806
Synonym:
Target: HDAC
Edaravone
Cat.No: T0407
Synonym: 依达拉奉右莰醇,依达拉奉,MCI-186
Target: Apoptosis, MMP, Free radical scavengers
Incyclinide
Cat.No: T15574
Synonym: COL-3,CMT-3
Target: MMP
SM-7368
Cat.No: T22115
Synonym:
Target: NF-κB
ARP-100
Cat.No: T14322
Synonym: MMP-2 Inhibitor III
Target: MMP
Doxycycline hydrochloride
Cat.No: T1140
Synonym: Doxylin,盐酸多西环素,Vibramycin,Hyclate
Target: MMP, Antibacterial, Antibiotic
Abametapir
Cat.No: T7459
Synonym: 5 5'-二甲基-2,2-联吡啶,HA-44,BRN 0123183
Target: MMP, Others, Parasite
o-Phenanthroline monohydrate
Cat.No: T7449
Synonym: Phenanthroline monohydrate,1, 10-Phenanthroline monohydrate,邻菲罗啉
Target: MMP
Marimastat
Cat.No: T6885
Synonym: BB2516,马立马司他,KB-R8898,TA2516
Target: MMP
Imidapril hydrochloride
Cat.No: T6542
Synonym: Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366
Target: RAAS
Indinavir sulfate
Cat.No: T5863
Synonym: L735524 sulfate,MK-639 sulfate,硫酸茚地那韦
Target: SARS-CoV, HIV Protease
TAPI1
Cat.No: T6009
Synonym: TAPI 1,TAPI,TAPI-1
Target: MMP
JC-10
Cat.No: TD0056
Synonym:
Target: MMP
Prinomastat
Cat.No: T12539L
Synonym: KB-R9896,AG3340
Target: MMP
Histatin 5 acetate
Cat.No: TP1741L
Synonym: Histatin 5 acetate (115966-68-2 Free base)
Target: MMP
MMP2-IN-3
Cat.No: T61271
Synonym:
Target: MMP
CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)
Cat.No: TP1501L
Synonym:
Target: MMP
Ro 28-2653
Cat.No: T26104
Synonym: Ro 28 2653,Ro-28-2653,Ro282653
Target: Others
Matlystatin A
Cat.No: T24431
Synonym:
Target: Others
ABT-518
Cat.No: T69503
Synonym:
Target: Others
alpha-RA-F
Cat.No: T25055
Synonym: α RA F,alphaRAF,α-RA-F,αRAF
Target: Others
Tanomastat
Cat.No: T16986
Synonym: BAY 12-9566
Target: MMP
XL-784
Cat.No: T13358
Synonym:
Target: MMP
S-3304
Cat.No: T70052
Synonym:
Target: Others
GW-3333
Cat.No: T27507
Synonym: GW 3333,GW3333
Target: Others
XL-784 free base
Cat.No: T13357
Synonym:
Target: Others
Histatin 5 TFA
Cat.No: T75755
Synonym:
Target:
Histatin 5
Cat.No: TP1741
Synonym:
Target:
Myristoyl tetrapeptide Ala-Ala-Pro-Val
Cat.No: T81728
Synonym:
Target:
CTTHWGFTLC, CYCLIC
Cat.No: TP1501
Synonym:
Target:
Histatin 5 (TFA)(115966-68-2,free)
Cat.No: TP1446
Synonym: Histatin 5 (TFA)
Target: MMP
Apratastat
Cat.No: T14312
Synonym:
Target: MMP, TNF
CTTHWGFTLC, CYCLIC TFA
Cat.No: T76017
Synonym:
Target:
RO314724
Cat.No: T71420
Synonym:
Target: Others
NNGH
Cat.No: T21735
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T3414 Morroniside

莫诺苷,奎宁树

Apoptosis; MMP; Pyroptosis Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用,可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T2993 Cordycepin

3'-Deoxyadenosine,虫草素

MMP; TNF; Antibacterial; Antibiotic; Autophagy Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物,在类风湿性关节炎滑膜成纤维细胞中,剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。
T4115 Auraptene

橙皮油内酯,7-geranyloxycoumarin,橙皮油素

MMP; BACE Neuroscience; Proteases/Proteasome
Auraptene 是一种丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子,包括 IL-6,IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5)的分泌。
T3860 Isoliquiritin apioside

MMP; p38 MAPK; NF-κB MAPK; NF-κB; Proteases/Proteasome
Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成,显著降低 PMA 诱导的MMP9活性增加,并抑制 PMA 诱导的MAPK 和NF-κB 活化。
TN1879 Lucideric acid A

Lucidenic acid A,赤芝酸A

MMP; p38 MAPK; JNK MAPK; Proteases/Proteasome
Lucideric acid A (Lucidenic acid A) 是分离自灵芝的天然产物,可抑制 PMA 诱导的MMP-9活性,具有抵抗肝癌细胞侵袭的作用。
T2967 Stigmasterol

Stigmasterin,beta-Stigmasterol,豆甾醇

MMP; Endogenous Metabolite Metabolism; Proteases/Proteasome
Stigmasterol (Stigmasterin) 是一种植物性甾醇,具有抑制胆固醇的特性,此外在风湿性疾病的研究中被评价为抗硬化因子。
T8259 Doxycycline monohydrate

水合强力霉素,强力霉素一水物

MMP; Antibacterial; Antibiotic; Parasite Microbiology/Virology; Proteases/Proteasome
Doxycycline monohydrate 是一种四环素抗生素,是广谱金属蛋白酶抑制剂,具有抗菌活性。
T6S0444 Salvianolic acid A

丹酚酸 A,Dan Phenolic Acid A

MMP Proteases/Proteasome
Salvianolic acid A (Dan Phenolic Acid A) 能够提高抑制基质金属钛酶 9 和抗炎作用,进而保护血脑屏障。
T2957 Arctigenin

牛蒡苷元,牛蒡子苷元,(-)-Arctigenin

Apoptosis; MMP; Influenza Virus; Autophagy Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
Arctigenin ((-)-Arctigenin) 是一种存在于牛蒡中的木脂素,具有抗氧化、抗肿瘤、抗炎和抗病毒活性。它可研究代谢紊乱和中枢神经系统功能障碍。
T3767 Polygalacic acid

Virgaureagenin G,毛果一枝黄花皂苷元G,远志酸

MMP; AChR; AChE Neuroscience; Proteases/Proteasome
Polygalacic acid (Virgaureagenin G) 是一种从远志 Polygala tenuifolia Willd 根中分离出来的三萜,可抑制 MMP 表达。它对认知障碍有显著的神经保护作用,PA 通过抑制乙酰胆碱酯酶活性,增加胆碱乙酰转移酶活性,提高海马和额皮质中的乙酰胆碱水平来提高胆碱能系统反应性。 它可以用于骨关节炎相关研究。
T2980 Chondroitin sulfate

Chonsurid,Chondroitin polysulfate,硫酸软骨素

MMP; Others; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism; Others; Proteases/Proteasome
Chondroitin sulfate (Chonsurid) 是一种糖胺聚糖,被广泛用于骨关节炎的研究。它能够减少炎症介质和凋亡过程,并能够减少炎性细胞因子,iNOS 和MMPs 产生。
T2987 (-)-Epigallocatechin

表没食子儿茶素,(-)-表没食子儿茶素,l-Epigallocatechin,Epigallocatechin,EGC

MMP; Autophagy Autophagy; Proteases/Proteasome
(-)-Epigallocatechin (Epigallocatechin) 是绿茶中含量最丰富的黄酮类天然产物,可与未折叠的天然多肽结合,阻止转化为淀粉样蛋白原纤维。
T3S0640 Triolein

三油酸甘油酯,Glycerol trioleate,甘油三油酸酯,Glycerine Trioleate

MMP; Others; Endogenous Metabolite Metabolism; Others; Proteases/Proteasome
Glycerol trioleate 是一种对称三酰甘油,可减少MMP-1的上调,具有很强的抗氧化、抗炎特性。
T5S1026 Apigenin-7-glucuronide

Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸

MMP Proteases/Proteasome
Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) 能够抑制基质金属蛋白酶的活性,其对 MMP-3 (IC50:12.87 μM),MMP-8 (IC50:22.39 μM),MMP-9 (IC50:17.52 μM),MMP-13 (IC50:0.27 μM)。
T6S2140 β-Anhydroicaritin

Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素

MMP; Others; TNF; Interleukin Apoptosis; Immunology/Inflammation; Others; Proteases/Proteasome
β-Anhydroicaritin 是从乳香提取的一种天然产物,具有重要的生物学和药理学作用,如抗骨质疏松症,雌激素调节和抗肿瘤特性。它改善牙周组织的降解,抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。它抑制细胞内 Ca2+的升高,并显著降低 iNOS 蛋白的表达。
T5680 Aloin(mixture of A&B)

芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷

MMP; IL Receptor; Antibacterial; Antifungal Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Aloin (mixture of A&B) 是一种从芦荟中分离出来的蒽醌衍生物。它是刺激性粒细胞基质金属蛋白酶的有效抑制剂。它具有多种生物活性,如抗炎、抗菌、抗真菌、抗氧化、抗肿瘤、抗糖尿病和免疫活性。
T2750 Ginkgolide C

银杏内酯C,BN-52022

MMP; Sirtuin; Endogenous Metabolite; AMPK Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Ginkgolide C (BN-52022) 是从银杏叶中分离到的一种黄酮类天然产物,可增强体内大鼠的心脏功能,具有减少血小板聚集,改善阿尔兹海默症等作用。
T2973 Astragaloside IV

AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV

MMP; ERK; Estrogen/progestogen Receptor; JNK Endocrinology/Hormones; MAPK; Proteases/Proteasome
Astragaloside IV (AS-IV) 是从黄芪中分离得到的一种皂苷,抑制ERK1/2和JNK 激活,在乳腺癌细胞 MDA-MB-231 中,下调(MMP)-2和(MMP)-9的信号通路。
T3850 Luteolin 7-O-glucuronide

Luteolin-7-glucuronide,木犀草素-7-O-葡萄糖醛酸苷

MMP Proteases/Proteasome
Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) 是一种自由基清除剂,能够抑制基质金属蛋白酶的活性,其对 MMP-1,MMP-3,MMP-8,MMP-9,MMP-13的IC50值分别为 17.63,7.99,11.42,12.85,0.03 μM。
T1687 Doxycycline

Vibramycin,多西环素,Doxiciclina,Doxytetracycline,Doxycyclinum,强力霉素

MMP; ribosome; Antibacterial; Antibiotic; Parasite Microbiology/Virology; Proteases/Proteasome
Doxycycline (Doxiciclina) 属于四环素类抗生素,是一种广谱的金属蛋白酶 (MMP) 抑制剂,具有口服活性。Doxycycline 具有抗菌活性和抗肿瘤活性。
T5S0045 Isofraxidin

6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶

MMP; ERK; p38 MAPK; TLR; COX Immunology/Inflammation; MAPK; Neuroscience; Proteases/Proteasome
Isofraxidin (Phytodolor) 是来自刺五加的香豆素成分,抑制MMP-7表达和人肝癌细胞侵袭。它作用于肝癌细胞,抑制ERK1/2磷酸化。它减弱iNOS 和COX-2表达,还抑制TLR4/髓样分化蛋白 2 复合物的形成。
T4S21320 ISOGINKGETIN

异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮

MMP; Others Others; Proteases/Proteasome
ISOGINKGETIN (4',4'''-Dimethylamentoflavone) 是一种MMP9抑制剂,也是一种Pre-mRNA Splicing 抑制剂。
T3813 20(R)-Ginsenoside Rh2

20(R)-人参皂苷 RH2,(20R)Ginsenoside Rh2,Ginsenoside Rh2,20(R)-人参皂苷Rh2

Apoptosis; MMP; HSV Apoptosis; Microbiology/Virology; Proteases/Proteasome
20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) 是人参皂苷 Rh2 的次要立体异构体,具有基质金属蛋白酶抑制作用。它有抗癌、抗炎和抗氧化活性。
T1205 Chloramphenicol

Chlornitromycin,Levomycetin,Chloromycetin,氯霉素

ribosome; HIF/HIF Prolyl-Hydroxylase; Antibacterial; Antibiotic Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Chloramphenicol (Chloromycetin) 是一种广谱抗生素,有效抑制细菌蛋白质生物合成。它主要作用于细菌 70S 核糖体的 50S 亚基,对肽基转移酶有活性,抑制肽键的形成。
T1687L Doxycycline (hyclate)

Doxycycline hydrochloride hemiethanolate hemihydrate,盐酸强力霉素,WC2031,Doxycycline hyclate

MMP; ribosome; Antibacterial; Antibiotic Microbiology/Virology; Proteases/Proteasome
Doxycycline hyclate (WC2031) 属于四环素类抗生素,是一种广谱的金属蛋白酶 (MMP) 抑制剂,具有口服活性。Doxycycline hyclate 具有抗菌活性和抗肿瘤活性。
T2769 3-Aminopropionitrile fumarate (2:1)

Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,3-氨基丙腈,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate

Others Others
3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) 是一种能抑制胶原蛋白(collagen)交联的山黧豆素。
TN2697 2,3-Dihydrohinokiflavone

MMP; Parasite; Antifection Microbiology/Virology; Proteases/Proteasome
2,3-Dihydrohinokiflavone 是基质金属蛋白酶 (MMP) 基因表达的抑制剂,对利什曼原虫具有很强的活性,IC50 为 1.6 μM。
TN4088 Futoenone

PAFR GPCR/G Protein
Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases, the molecular modelings of these compounds indicate the preferred binding of the P2' site of the enzymes. Neolignan derivative compounds of the 2,4-diaryl-1,3-dithiolane and futoenone variety exhibit both platelet activating factor receptor(PAF)and 5-lipoxygenase antagonist activity.
TN4592 Murrangatin

IL Receptor; TNF; COX; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line,

天然产物

Morroniside
Cat.No: T3414
Synonym: 莫诺苷,奎宁树
Target: Apoptosis, MMP, Pyroptosis
Cordycepin
Cat.No: T2993
Synonym: 3'-Deoxyadenosine,虫草素
Target: MMP, TNF, Antibacterial, Antibiotic, Autophagy
Auraptene
Cat.No: T4115
Synonym: 橙皮油内酯,7-geranyloxycoumarin,橙皮油素
Target: MMP, BACE
Isoliquiritin apioside
Cat.No: T3860
Synonym:
Target: MMP, p38 MAPK, NF-κB
Lucideric acid A
Cat.No: TN1879
Synonym: Lucidenic acid A,赤芝酸A
Target: MMP, p38 MAPK, JNK
Stigmasterol
Cat.No: T2967
Synonym: Stigmasterin,beta-Stigmasterol,豆甾醇
Target: MMP, Endogenous Metabolite
Doxycycline monohydrate
Cat.No: T8259
Synonym: 水合强力霉素,强力霉素一水物
Target: MMP, Antibacterial, Antibiotic, Parasite
Salvianolic acid A
Cat.No: T6S0444
Synonym: 丹酚酸 A,Dan Phenolic Acid A
Target: MMP
Arctigenin
Cat.No: T2957
Synonym: 牛蒡苷元,牛蒡子苷元,(-)-Arctigenin
Target: Apoptosis, MMP, Influenza Virus, Autophagy
Polygalacic acid
Cat.No: T3767
Synonym: Virgaureagenin G,毛果一枝黄花皂苷元G,远志酸
Target: MMP, AChR, AChE
Chondroitin sulfate
Cat.No: T2980
Synonym: Chonsurid,Chondroitin polysulfate,硫酸软骨素
Target: MMP, Others, Endogenous Metabolite, NO Synthase
(-)-Epigallocatechin
Cat.No: T2987
Synonym: 表没食子儿茶素,(-)-表没食子儿茶素,l-Epigallocatechin,Epigallocatechin,EGC
Target: MMP, Autophagy
Triolein
Cat.No: T3S0640
Synonym: 三油酸甘油酯,Glycerol trioleate,甘油三油酸酯,Glycerine Trioleate
Target: MMP, Others, Endogenous Metabolite
Apigenin-7-glucuronide
Cat.No: T5S1026
Synonym: Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸
Target: MMP
β-Anhydroicaritin
Cat.No: T6S2140
Synonym: Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素
Target: MMP, Others, TNF, Interleukin
Aloin(mixture of A&B)
Cat.No: T5680
Synonym: 芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷
Target: MMP, IL Receptor, Antibacterial, Antifungal
Ginkgolide C
Cat.No: T2750
Synonym: 银杏内酯C,BN-52022
Target: MMP, Sirtuin, Endogenous Metabolite, AMPK
Astragaloside IV
Cat.No: T2973
Synonym: AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV
Target: MMP, ERK, Estrogen/progestogen Receptor, JNK
Luteolin 7-O-glucuronide
Cat.No: T3850
Synonym: Luteolin-7-glucuronide,木犀草素-7-O-葡萄糖醛酸苷
Target: MMP
Doxycycline
Cat.No: T1687
Synonym: Vibramycin,多西环素,Doxiciclina,Doxytetracycline,Doxycyclinum,强力霉素
Target: MMP, ribosome, Antibacterial, Antibiotic, Parasite
Isofraxidin
Cat.No: T5S0045
Synonym: 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶
Target: MMP, ERK, p38 MAPK, TLR, COX
ISOGINKGETIN
Cat.No: T4S21320
Synonym: 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮
Target: MMP, Others
20(R)-Ginsenoside Rh2
Cat.No: T3813
Synonym: 20(R)-人参皂苷 RH2,(20R)Ginsenoside Rh2,Ginsenoside Rh2,20(R)-人参皂苷Rh2
Target: Apoptosis, MMP, HSV
Chloramphenicol
Cat.No: T1205
Synonym: Chlornitromycin,Levomycetin,Chloromycetin,氯霉素
Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic
Doxycycline (hyclate)
Cat.No: T1687L
Synonym: Doxycycline hydrochloride hemiethanolate hemihydrate,盐酸强力霉素,WC2031,Doxycycline hyclate
Target: MMP, ribosome, Antibacterial, Antibiotic
3-Aminopropionitrile fumarate (2:1)
Cat.No: T2769
Synonym: Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,3-氨基丙腈,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate
Target: Others
2,3-Dihydrohinokiflavone
Cat.No: TN2697
Synonym:
Target: MMP, Parasite, Antifection
Futoenone
Cat.No: TN4088
Synonym:
Target: PAFR
Murrangatin
Cat.No: TN4592
Synonym:
Target: IL Receptor, TNF, COX, Prostaglandin Receptor
Cat. No. Product Name Species Expression System
TMPH-02782 TIMP4 Protein, Mouse, Recombinant (His & SUMO)

Timp4,Metalloproteinase inhibitor 4,Tissue inhibitor of ...

Mouse E. coli
TIMP4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-01289 TIMP-4 Protein, Human, Recombinant (His)

TIMP4,TIMP-4,Metalloproteinase inhibitor 4,Tissue inhibitor ...

Human HEK293 Cells
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
TMPJ-00101 TIMP-2 Protein, Human, Recombinant (His)

Tissue Inhibitor of Metalloproteinases 2,TIMP2,CSC-...

Human HEK293 Cells
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and i...
TMPH-01665 TIMP3 Protein, Human, Recombinant (His)

Tissue inhibitor of metalloproteinases 3,TIMP3,Prot...

Human E. coli
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain)

HME,ME,MMP-12,MME,matrix metallopeptidase 12

Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPK-01286 MMP-8 Protein, Cynomolgus, Recombinant (His)

Collagenase 2,HNC,CLG1,MMP8,PMNL-CL

Cynomolgus HEK293 Cells
Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was signifi...
TMPK-00093 TIMP-1 Protein, Mouse, Recombinant (hFc)

TPA-S1,CLGI,TIMP-1,EPO,TIMP,EPA,EPATIMP-1,TPAS1

Mouse HEK293 Cells
Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner.
TMPJ-00916 TIMP-2 Protein, Mouse, Recombinant (His)

metalloproteinase inhibitor 2,Tissue inhibitor of metallopro...

Mouse HEK293 Cells
Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP‑1, TIMP‑2, TIMP‑3, and TIMP‑4. The TIMP-2 is detected in testis, retina, hippocampus and cerebral cortex. The function of TIMP 2 protein is to inhibit MMPs non covalently by the formation of binary complexes. Complexes with metalloproteinases (such as collagenases) and irreversi...
TMPH-02106 SH3PXD2A Protein, Human, Recombinant (His & Myc)

SH3PXD2A,SH3 multiple domains protein 1,SH3 and PX domain-co...

Human E. coli
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
TMPH-02285 USP6 Protein, Human, Recombinant (His & KSI)

Proto-oncogene TRE-2,Ubiquitin-specific-processing protease ...

Human E. coli
Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
TMPJ-00159 EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated

Membrane glycoprotein gp42,Basigin,HT7 antigen,Bsg,Basic imm...

Human HEK293 Cells
Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore...
TMPH-01297 DDR1 Protein, Human, Recombinant (aa 21-417, His)

EDDR1,MCK-10,Epithelial discoidin domain-containing receptor...

Human HEK293 Cells
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell...
TMPY-04100 MMP-26 Protein, Human, Recombinant

matrix metallopeptidase 26,MMP26

Human E. coli
MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene. MMP26 is a member of matrix metalloproteinases (MMPs) and has been reported to be highly expressed in many cancers. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. It may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin, and alpha-1 proteinase inhibitor, and is also able to activate progelatinase B. MMP26 is a target gene of miR-125b, and the expre...
TMPY-02954 ADAMTSL1 Protein, Human, Recombinant (His)

PUNCTIN,ADAMTSL-1,C9orf94,ADAMTS-like 1,ADAMTSR1

Human Baculovirus Insect Cells
ADAMTSL1 is a secreted molecule resembling members of the ADAMTS protein family of matrix metalloproteinases. Both ADAMTS proteins and ADAM protein family contain a disintegrin and a metalloprotease domain. Metallospondins is collective term for members of ADAMTS protein family. ADAMTS proteins lack the EGF-like domain found normally in members of the ADAM protein family. They also do not possess the canonical disintegrin sequence found in the ADAM protein family. It contains the domains found i...
TMPY-02404 ADAM9 Protein, Mouse, Recombinant (His)

mKIAA0021,AU020942,ADAM metallopeptidase domain 9,Mltng,MDC9

Mouse HEK293 Cells
ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD40, VCAM-1, and VE-cadherin, and could represent a potential t...
TMPJ-00957 MMP-9 Protein, Mouse, Recombinant (His)

Matrix metalloproteinase-9,92 kDa gelatinase,GELB,Gelatinase...

Mouse HEK293 Cells
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by ker...
TMPJ-00362 MMP-2 Protein, Human, Recombinant (His)

72 kDa Gelatinase,TBE-1,Gelatinase A,Matrix Metalloproteinas...

Human HEK293 Cells
72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathologic...
TMPJ-00948 Endostatin Protein, Mouse, Recombinant (His)

antiangiogenic agent,type XVIII,collagen α-1(XVIII)chain,col...

Mouse HEK293 Cells
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑terminal ~27 aa of Endostatin appear to contain the majority of its activity. This region contains zinc binding sites that are thought to be critical for its anti‑endothelial and anti‑tumor effects, as well as multiple cleavage sites that, when used, can modify its activity. Mouse End...

重组蛋白

TIMP4 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02782
Species: Mouse
Expression System: E. coli
TIMP-4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01289
Species: Human
Expression System: HEK293 Cells
TIMP-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00101
Species: Human
Expression System: HEK293 Cells
TIMP3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01665
Species: Human
Expression System: E. coli
MMP-12 Protein, Human, Recombinant (catalytic domain)
Cat.No: TMPY-02869
Species: Human
Expression System: E. coli
MMP-8 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01286
Species: Cynomolgus
Expression System: HEK293 Cells
TIMP-1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00093
Species: Mouse
Expression System: HEK293 Cells
TIMP-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00916
Species: Mouse
Expression System: HEK293 Cells
SH3PXD2A Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02106
Species: Human
Expression System: E. coli
USP6 Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-02285
Species: Human
Expression System: E. coli
EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00159
Species: Human
Expression System: HEK293 Cells
DDR1 Protein, Human, Recombinant (aa 21-417, His)
Cat.No: TMPH-01297
Species: Human
Expression System: HEK293 Cells
MMP-26 Protein, Human, Recombinant
Cat.No: TMPY-04100
Species: Human
Expression System: E. coli
ADAMTSL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02954
Species: Human
Expression System: Baculovirus Insect Cells
ADAM9 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02404
Species: Mouse
Expression System: HEK293 Cells
MMP-9 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00957
Species: Mouse
Expression System: HEK293 Cells
MMP-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00362
Species: Human
Expression System: HEK293 Cells
Endostatin Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00948
Species: Mouse
Expression System: HEK293 Cells
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