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Search Results for " foam "

Targets Recommended: Acyltransferase

6

抑制剂 & 化合物

5

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T23550	YM-750 YM 750	Acyltransferase	Metabolism
	YM-750 是一种有效的酰基:胆固醇酰基转移酶(ACAT)抑制剂，IC50为0.18 μM。
T13171	TMN355 2-氯-N-[(9H-芴-9-氨基)羰基]-6-氟苯甲酰胺	Others	Others
	TMN355 是一种化学亲环素 A 抑制剂，能够抑制泡沫细胞形成和细胞因子分泌，可用于动脉粥样硬化的研究。
T84863	Tridecafluorohexane-1-sulfonic acid potassium salt	Others	Others
	Tridecafluorohexane-1-sulfonic acid potassium salt是全氟阴离子表面活性剂，应用于电镀作为铬雾抑制剂、润湿剂，以及氟蛋白泡沫灭火剂的添加剂。
T73906	Myristoyl glutamic acid sodium	Others	Others
	Myristoyl glutamic acid sodium，即化妆品/面霜中常用的肉豆蔻酰谷氨酸成分。作为氨基酸类表面活性剂，其清洁能力温和且具备发泡性和轻度抑菌作用。
T70356	F-1394	Others	Others
	F-1394 is an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. F-1394 both prevents the formation of atherosclerosis and accelerates its regression without affecting the serum TC level, indicating that F-1394 acts directly on the arterial wall. F-1394 significantly reduced neointimal thickening and the extent of macrophages in lesions without affecting serum cholesterol levels. In vitro, F-1394 attenuated foam cell formation in mouse peritoneal macrophages.
T35985	CAY10487	Others	Others
	The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity. The percent area occupied by the atherosclerotic lesion in rabbits supplemented with 0.05% CAY10487 in the diet was 16.1% compared to 53.5% in control rabbits....

化合物

Cat.No: T23550

Synonym: YM 750

Target: Acyltransferase

Cat.No: T13171

Synonym: 2-氯-N-[(9H-芴-9-氨基)羰基]-6-氟苯甲酰胺

Target: Others

Tridecafluorohexane-1-sulfonic acid potassium salt

Cat.No: T84863

Target: Others

Myristoyl glutamic acid sodium

Cat.No: T73906

Target: Others

Cat.No: T70356

Target: Others

Cat.No: T35985

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3244	2-Deoxy-2-sulfoamino-D-glucose sodium 氨基葡萄糖硫酸钠盐,N-Sulfo-D-glucosamine sodium salt,N-Sulfo-glucosamine sodium salt,GlcN-2S,2-Deoxy-2-sulfamino-D-glucopyranose	Others; Endogenous Metabolite	Metabolism; Others
	2-Deoxy-2-sulfoamino-D-glucose sodium (GlcN-2S) 是内源性代谢产物的一种。
T3S1612	kuwanon G 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G	Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂，具有杀菌作用。
TN5097	Tanshindiol C	LDL; Histone Methyltransferase	Chromatin/Epigenetic; Metabolism
	Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique anti-cancer activity whose mechani
T27977	Manzamine A Keramamine A	Others	Others
	Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram negative and gram positive bacteria, an
TN4600	Myrianthic acid	PAFR; AChR	GPCR/G Protein; Neuroscience
	Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-density lipoproteins at a 50 uM concentration. Myrianthic acid is equivalently inhibitive as acetylsalicylic acid (IC50: 57.0 microM) on epinephrine induced platelet aggregation.

天然产物

2-Deoxy-2-sulfoamino-D-glucose sodium

Cat.No: T3244

Synonym: 氨基葡萄糖硫酸钠盐,N-Sulfo-D-glucosamine sodium salt,N-Sulfo-glucosamine sodium salt,GlcN-2S,2-Deoxy-2-sulfamino-D-glucopyranose

Target: Others, Endogenous Metabolite

Cat.No: T3S1612

Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Cat.No: TN5097

Target: LDL, Histone Methyltransferase

Cat.No: T27977

Synonym: Keramamine A

Target: Others

Myrianthic acid

Cat.No: TN4600

Target: PAFR, AChR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04813	ACAT2 Protein, Rat, Recombinant (His) acetyl-CoA acetyltransferase 2	Rat	E. coli
	Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage foam-cell formation, in absorbing dietary cholesterol, and in supplying cholesteryl esters as part of the core lipid for lipoprotein synthesis and assembly. The key difference in tissue distributio...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc) Pla2g10,Group X secretory phospholipase A2,Phosphatidylcholi...	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li...

重组蛋白

ACAT2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-04813

Species: Rat

Expression System: E. coli

PLA2G10 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02690

Species: Mouse

Expression System: E. coli

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