|
TMPH-02759
|
LIRE1 Protein, Mouse, Recombinant (His & Myc)
Transposase element L1Md-A101/L1Md-A102/L1Md-A2,LIN...
|
Mouse
|
E. coli
|
|
LIRE1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli. |
|
TMPH-01165
|
CREB1 Protein, Human, Recombinant (His)
CREB-1,cAMP-responsive element-binding protein 1,Cy...
|
Human
|
E. coli
|
|
CREB1 Protein, Human, Recombinant (His) is expressed in E. coli. |
|
TMPH-02614
|
CREB5 Protein, Mouse, Recombinant (His)
Creb5,Cyclic AMP-responsive element-binding protein...
|
Mouse
|
E. coli
|
|
Binds to the cAMP response element and activates transcription. |
|
TMPY-03627
|
CREB3L1 Protein, Human, Recombinant (aa 396-519, His)
OASIS,PSEC0238,cAMP responsive element binding prot...
|
Human
|
HEK293 Cells
|
|
CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting prol... |
|
TMPH-00082
|
DREB2C Protein, Arabidopsis thaliana, Recombinant (His)
Dehydration-responsive element-binding protein 2C,D...
|
Arabidopsis thaliana
|
E. coli
|
|
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription. DREB2C Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.9 kDa and the accession number is Q8LFR2. |
|
TMPH-01915
|
PREB Protein, Human, Recombinant (His & Myc)
Mammalian guanine nucleotide exchange factor mSec12,Prolacti...
|
Human
|
E. coli
|
|
PREB Protein, Human, Recombinant (His & Myc) is expressed in E. coli. |
|
TMPJ-01241
|
DTD1 Protein, Human, Recombinant (His)
DUE-B,D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding elem...
|
Human
|
HEK293 Cells
|
|
D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defens... |
|
TMPJ-00721
|
ZBED1 Protein, Human, Recombinant (His)
TRAMP,dREF Homolog,ALTE,DREF,ZBED1,Zinc Finger BED Domain-Co...
|
Human
|
E. coli
|
|
Zinc Finger BED Domain-Containing Protein 1 (ZBED1) contains one BED-type zinc finger and is found in the cell nucleus. ZBED1 is widely expressed, highly in heart, skeletal muscle, spleen and placenta. The expression of ZBED1 is usually linked to the cell cycle. During the G1/S phase, the expression is increasing. During the S/G2 phage, the expression reaches to the highest, and then decreasing. ZBED1 exists in homodimer forms, which can bind to 5’-TGTCCG[CT]GA[CT]A-3’ DNA elements, that can be ... |
|
TMPH-01781
|
NSMCE3 Protein, Human, Recombinant (His)
Necdin-like protein 2,MAGE-G1 antigen,Non-structural mainten...
|
Human
|
E. coli
|
|
NSMCE3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.4 kDa and the accession number is Q96MG7. |
|
TMPH-02976
|
YBX1 Protein, Mouse, Recombinant (His)
Y-box-binding protein 1,DNA-binding protein B,CCAAT-binding ...
|
Mouse
|
P. pastoris (Yeast)
|
|
YBX1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.6 kDa and the accession number is P62960. |
|
TMPH-00973
|
DHX36 Protein, Human, Recombinant (His & Myc)
DEAH-box protein 36,G4R1,ATP-dependent DNA/RNA helicase DHX3...
|
Human
|
E. coli
|
|
DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is Q9H2U1. |
|
TMPH-02084
|
SRRM2 Protein, Human, Recombinant (His & Myc)
Splicing coactivator subunit SRm300,SRRM2,Serine/arginine-ri...
|
Human
|
Baculovirus Insect Cells
|
|
SRRM2 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. |
|
TMPJ-01288
|
KLF6 Protein, Human, Recombinant
CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...
|
Human
|
E. coli
|
|
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul... |
|
TMPY-03794
|
CEBP gamma Protein, Human, Recombinant (His)
CCAAT/enhancer binding protein (C/EBP), gamma,GPE1BP,CEBP γ,...
|
Human
|
E. coli
|
|
CEBPG, also known as CEBP gamma, is a transcription factor which belongs to the CEBP family. Members of this family regulate viral and cellular CCAAT/enhancer element-mediated transcription. CEBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. CEBPG binds to the enhancer element PRE-I of the IL-4 gene. It Might change the DNA-binding specificit... |
|
TMPH-02142
|
ERR1 Protein, Human, Recombinant (GST)
Steroid hormone receptor ERR1,Estrogen receptor-like 1,Nucle...
|
Human
|
E. coli
|
|
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
|
TMPH-00367
|
Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (His & SUMO)
Apoptin,VP3
|
CAV
|
E. coli
|
|
May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.3 kDa and the accession number is Q99152. |
|
TMPH-00366
|
Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (GST)
VP3,Apoptin
|
CAV
|
E. coli
|
|
May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 40.3 kDa and the accession number is Q99152. |
|
TMPH-00365
|
Chicken anemia virus (isolate USA 26p4) Apoptin Protein (His)
VP3,Apoptin
|
CAV
|
E. coli
|
|
May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate USA 26p4) Apoptin Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.1 kDa and the accession number is P54095. |
|
TMPJ-00886
|
ATF1 Protein, Human, Recombinant (His)
Cyclic AMP-dependent transcription factor ATF-1,Activating t...
|
Human
|
E. coli
|
|
Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It also binds to the ... |
|
TMPY-04468
|
STK16 Protein, Human, Recombinant (His & NusA)
MPSK,serine/threonine kinase 16,TSF1,KRCT,PKL12
|
Human
|
E. coli
|
|
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or c... |
|
TMPH-03713
|
ELAVL4 Protein, Xenopus tropicalis, Recombinant (His)
ELAVL4,HuD,Hu-antigen D,ELAV-like protein 4,PNEM
|
Xenopus tropicalis
|
E. coli
|
|
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in the 3' untranslated region (3'UTR) of target mRNAs. Mainly plays a role in neuron-specific RNA processing. |
|
TMPJ-01080
|
HSF2 Protein, Human, Recombinant (His)
HSF 2,Heat Shock Factor Protein 2,HSF2,HSTF2,Heat Shock Tran...
|
Human
|
E. coli
|
|
Heat Shock Factor Protein 2 (HSF2) belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. HSF2 is widely expressed in many cells and tissues. HSF2 is located on Cytoplasmic during normal growth. But when it is activited, HSF2 moves to the nucleus. |
|
TMPH-01461
|
HNRNPA3 Protein, Human, Recombinant (His & Myc)
Heterogeneous nuclear ribonucleoprotein A3,HNRNPA3
|
Human
|
E. coli
|
|
Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing. HNRNPA3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.6 kDa and the accession number is P51991. |
|
TMPH-01281
|
ELAVL3 Protein, Human, Recombinant (His)
PLE21,Hu-antigen C,ELAVL3,ELAV-like protein 3,HUC
|
Human
|
P. pastoris (Yeast)
|
|
RNA-binding protein that binds to AU-rich element (ARE) sequences of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Plays a role in the stabilization of GAP43 mRNA and in spatial learning. |
|
TMPH-01550
|
Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)
Interferon kappa,IFNK
|
Human
|
E. coli
|
|
May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin. |
|
TMPH-01798
|
Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)
Nucleolar transcription factor 1,Upstream-binding factor 1,U...
|
Human
|
E. coli
|
|
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 107.9 kDa and the accession number is P17480. |
|
TMPH-01799
|
Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)
Nucleolar transcription factor 1,Autoantigen NOR-90,UBTF,Ups...
|
Human
|
E. coli
|
|
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 95.2 kDa and the accession number is P17480. |
|
TMPJ-00689
|
EIF1B Protein, Human, Recombinant (His)
Protein Translation Factor SUI1 Homolog GC20,EIF1B,Eukaryoti...
|
Human
|
E. coli
|
|
Eukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulating the activity of ribosomal subunits 43S, 48S and 40S. EIF1B enables 43S ribosomal complexes to distinguish between cognate and near-cognate initiation codons, perceiving the nucleotide content of initiation codons. |
|
TMPH-03711
|
PPAR gamma Protein, Xenopus laevis, Recombinant (His)
Nuclear receptor subfamily 1 group C member 3,Peroxisome pro...
|
Xenopus laevis
|
E. coli
|
|
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm. |
|
TMPH-01864
|
PITHD1 Protein, Human, Recombinant (His & Myc)
PITHD1,PITH domain-containing protein 1
|
Human
|
E. coli
|
|
Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene. PITHD1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.6 kDa and the accession number is Q9GZP4. |
|
TMPH-00738
|
TetR5 Protein, E. coli, Recombinant (His)
Tetracycline repressor protein class E,tetR
|
E. coli
|
E. coli
|
|
TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. TetR5 Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is P21337. |
|
TMPH-00737
|
TetR2 Protein, E. coli, Recombinant (His & SUMO)
tetR,Tetracycline repressor protein class B from transposon ...
|
E. coli
|
E. coli
|
|
TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. TetR2 Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.4 kDa and the accession number is P04483. |
|
TMPH-00039
|
Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)
Single-strand DNA-binding protein,63.5 kDa virulence protein...
|
Agrobacterium fabrum
|
E. coli
|
|
Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence composition. Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 70.3 kDa and the accession number is P08062. |
|
TMPH-00077
|
IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
IAA17,Auxin response 3,Indoleacetic acid-induced protein 17,...
|
Arabidopsis thaliana
|
E. coli
|
|
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E.... |
|
TMPH-01796
|
NR4A1 Protein, Human, Recombinant (His & Myc)
ST-59,NR4A1,Nuclear hormone receptor NUR/77,Orphan nuclear r...
|
Human
|
E. coli
|
|
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury. NR4A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expre... |
|
TMPH-01463
|
HNRNPL Protein, Human, Recombinant (His & SUMO)
HNRNPL,Heterogeneous nuclear ribonucleoprotein L
|
Human
|
E. coli
|
|
Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter. HNRNPL Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6x... |
|
TMPU-00003
|
STAT2 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of... |
|
TMPH-01699
|
SMAD2 Protein, Human, Recombinant (His & SUMO)
JV18-1,SMAD2,SMAD family member 2,Mothers against decapentap...
|
Human
|
E. coli
|
|
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3... |
|
TMPH-02103
|
SRF Protein, Human, Recombinant (His)
SRF,Serum response factor
|
Human
|
P. pastoris (Yeast)
|
|
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupli... |
|
TMPK-01380
|
LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
LIB,EGM_11224,LRRC15
|
Cynomolgus,Rhesus
|
HEK293 Cells
|
|
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... |
|
TMPH-00541
|
Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)
Latent membrane protein 1,Protein p63,LMP1
|
EBV
|
E. coli
|
|
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... |
|
TMPH-02613
|
ATF-5 Protein, Mouse, Recombinant (His & Myc)
Transcription factor ATFx,Transcription factor-like protein ...
|
Mouse
|
E. coli
|
|
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcrip... |
|
TMPK-01070
|
LRRC15 Protein, Mouse, Recombinant (His)
LIB,LRRC15
|
Mouse
|
HEK293 Cells
|
|
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... |
|
TMPK-00338
|
LRRC15 Protein, Human, Recombinant (His & Avi)
LRRC15,LIB
|
Human
|
CHO Cells
|
|
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... |
|
TMPK-01309
|
LRRC15 Protein, Canine, Recombinant (His)
LIB,LRRC15
|
Canine
|
HEK293 Cells
|
|
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... |
|
TMPY-03496
|
EBAG9 Protein, Human, Recombinant (His)
EB9,PDAF,estrogen receptor binding site associated, antigen,...
|
Human
|
E. coli
|
|
RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in s... |
|
TMPJ-00913
|
MPZ Protein, Human, Recombinant (His)
Myelin Peripheral Protein,Myelin Protein P0,MPZ,Myelin Prote...
|
Human
|
HEK293 Cells
|
|
Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain... |
|
TMPY-03606
|
ECSIT Protein, Human, Recombinant (His)
ECSIT signalling integrator,SITPEC
|
Human
|
E. coli
|
|
ECSIT is an adapter protein of the toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Activation of NF-kappaB as a consequence of signaling through the Toll and IL-1 receptors is a major element of innate immune responses. ECSIT is specific for the Toll/IL-1 pathways and is a regulator of MEKK-1 processing. It bridges TRAF6 to MEKK-1. Expression of wild-type ECSIT accelerates processing of MEKK-1, whereas a dominant-negative fragment of ECS... |
|
TMPY-03615
|
CSEN Protein, Human, Recombinant (His)
Kv channel interacting protein 3, calsenilin,DREAM,KCHIP3,CS...
|
Human
|
E. coli
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KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. CSEN also functions as a calc... |
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TMPH-00542
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Epstein-Barr virus (strain Raji) LMP1 Protein (His)
Latent membrane protein 1,LMP1,Protein p63
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EBV
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P. pastoris (Yeast)
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Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein... |
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