|
TMPY-04122
|
ATOX1 Protein, Human, Recombinant (His)
HAH1,ATX1,antioxidant 1 copper chaperone
|
Human
|
E. coli
|
|
ATOX1 is a cytoplasmic copper chaperone that interacts with the copper-binding domain of the membrane copper transporters ATP7A and ATP7B. ATOX1 has also been suggested to have a potential anti-oxidant activity. As the trace element copper is essential, but extremely toxic in high concentrations, intracellular copper concentrations are tightly controlled. Once in the cell, copper is distributed by metallochaperones, including the small cytoplasmic protein ATOX1. ATOX1 plays an important role in ... |
|
TMPY-03341
|
ASF1B Protein, Human, Recombinant (His)
anti-silencing function 1B histone chaperone,CIA-II
|
Human
|
Baculovirus Insect Cells
|
|
The histone chaperone anti-silencing factor 1a (ASF1a) interacts with MDC1 and is recruited to sites of DSBs to facilitate the interaction of phospho-ATM with MDC1 and phosphorylation of MDC1, which are required for the recruitment of RNF8/RNF168 histone ubiquitin ligases. Thus, ASF1a deficiency reduces histone ubiquitination at DSBs, decreasing the recruitment of 53BP1, and decreases NHEJ, rendering cells more sensitive to DSBs. This role of ASF1a in DSB repair cannot be provided by the closely... |
|
TMPH-00189
|
HtpG Protein, Bacteroides fragilis, Recombinant (His & Myc & SUMO)
Chaperone protein HtpG,Heat shock protein HtpG,htpG...
|
Bacteroides fragilis
|
E. coli
|
|
Molecular chaperone. Has ATPase activity. HtpG Protein, Bacteroides fragilis, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 57.0 kDa and the accession number is Q5LCH4. |
|
TMPH-00592
|
DnaK Protein, E. coli, Recombinant (His)
Chaperone protein DnaK,dnaK,Heat shock protein 70,H...
|
E. coli
|
E. coli
|
|
Acts as a chaperone. |
|
TMPH-00593
|
DnaK Protein, E. coli, Recombinant (Yeast, His)
HSP70,Heat shock protein 70,Heat shock 70 kDa protein,Ch...
|
E. coli
|
P. pastoris (Yeast)
|
|
Acts as a chaperone. |
|
TMPJ-00717
|
BAG2 Protein, Human, Recombinant (His)
BAG-2,BAG Family Molecular Chaperone Regulator 2,BA...
|
Human
|
E. coli
|
|
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
|
TMPH-00594
|
HtpG Protein, E. coli, Recombinant (His)
Chaperone protein HtpG,Heat shock protein C62.5,Hea...
|
E. coli
|
E. coli
|
|
Molecular chaperone. Has ATPase activity. |
|
TMPH-00595
|
HtpG Protein, E. coli, Recombinant
High temperature protein G,Heat shock protein C62.5,Heat sho...
|
E. coli
|
E. coli
|
|
Molecular chaperone. Has ATPase activity. |
|
TMPH-01925
|
PTGES3 Protein, Human, Recombinant (E. coli, His)
Telomerase-binding protein p23,Hsp90 co-chaperone,C...
|
Human
|
E. coli
|
|
PTGES3 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. |
|
TMPH-02534
|
BAG3 Protein, Mouse, Recombinant (His)
Bcl-2-associated athanogene 3,Bag3,Bcl-2-binding protein Bis...
|
Mouse
|
P. pastoris (Yeast)
|
|
BAG3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is Q9JLV1. |
|
TMPJ-01399
|
ASF1A Protein, Human, Recombinant (His, T7)
CIA,Anti-Silencing Function Protein 1 Homolog A,ASF1A,Histon...
|
Human
|
E. coli
|
|
Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associat... |
|
TMPH-02535
|
BAG3 Protein, Mouse, Recombinant (His & SUMO)
Bcl-2-associated athanogene 3,Bis,BAG-3,BAG family molecular...
|
Mouse
|
E. coli
|
|
BAG3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 77.7 kDa and the accession number is Q9JLV1. |
|
TMPH-01926
|
PTGES3 Protein, Human, Recombinant (His)
Prostaglandin E synthase 3,Cytosolic prostaglandin E2 syntha...
|
Human
|
P. pastoris (Yeast)
|
|
PTGES3 Protein, Human, Recombinant (His) is expressed in Yeast. |
|
TMPH-01606
|
BAG6 Protein, Human, Recombinant (His & Myc)
BAG-6,Protein G3,BAG family molecular chaperone reg...
|
Human
|
Baculovirus Insect Cells
|
|
BAG6 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 38.7 kDa and the accession number is P46379. |
|
TMPH-02639
|
HSPA5 Protein, Mouse, Recombinant (His)
78 kDa glucose-regulated protein,Immunoglobulin heavy chain-...
|
Mouse
|
P. pastoris (Yeast)
|
|
HSPA5 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 72.5 kDa and the accession number is P20029. |
|
TMPH-02638
|
HSPA5 Protein, Mouse, Recombinant (E. coli, His)
Hspa5,Heat shock protein 70 family protein 5,Endoplasmic ret...
|
Mouse
|
E. coli
|
|
Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate. Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ER... |
|
TMPH-01605
|
BAG6 Protein, Human, Recombinant (E. coli, His & Myc)
BAT3,BAG6,HLA-B-associated transcript 3,BCL2-associated atha...
|
Human
|
E. coli
|
|
BAG6 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.7 kDa and the accession number is P46379. |
|
TMPY-00541
|
LON PROTEASE Protein, E. coli, Recombinant (His)
|
E. coli
|
E. coli
|
|
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, th... |
|
TMPY-03962
|
AFM Protein, Human, Recombinant (His)
afamin,ALBA,ALB2,ALF
|
Human
|
HEK293 Cells
|
|
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of... |
|
TMPH-00758
|
EspK Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
espK,ESX-1 secretion-associated protein EspK
|
Mycobacterium tuberculosis
|
E. coli
|
|
May act as a chaperone that facilitates EspB secretion through an interaction with EccCb1. |
|
TMPH-00887
|
AHSA1 Protein, Human, Recombinant (GST)
C14orf3,p38,Activator of 90 kDa heat shock protein ATPase ho...
|
Human
|
E. coli
|
|
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. AHSA1 Protein, Human, Recombinant (GST) is expressed i... |
|
TMPH-00527
|
Fibritin Protein, Enterobacteria phage T4, Recombinant (His & SUMO)
wac,Whisker antigen control protein,Collar protein,Fibritin
|
Enterobacteria phage T4
|
E. coli
|
|
Chaperone involved in tail fiber assembly and retraction. Acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. During phage assembly, twelve fibritin molecules attach to the phage neck via gp13: six molecules forming the collar and six molecules forming the whiskers. |
|
TMPH-01690
|
TIM14 Protein, Human, Recombinant (GST)
Mitochondrial import inner membrane translocase subunit TIM1...
|
Human
|
E. coli
|
|
Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity. |
|
TMPH-02991
|
Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (E. coli, His)
14 kDa antigen,Acr,16 kDa antigen,HSP 16.3
|
Mycobacterium bovis
|
E. coli
|
|
Acts as a chaperone. Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.1 kDa and the accession number is P0A5B8. |
|
TMPH-00682
|
Trigger factor Protein, E. coli O157:H7, Recombinant (Avi & His & MBP), Biotinylated
tig,PPIase,Trigger factor
|
E. coli
|
E. coli
|
|
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. |
|
TMPY-01451
|
MESDC2 Protein, Human, Recombinant (His)
MESD,mesoderm development candidate 2,BOCA
|
Human
|
HEK293 Cells
|
|
MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside... |
|
TMPJ-00664
|
Calmegin Protein, Human, Recombinant (His)
Calmegin,CLGN
|
Human
|
HEK293 Cells
|
|
Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. The functions during spermatogenesis as a chaperone for a range of client proteins that is important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. It is required for normal male fertility, normal sperm migration from the uterus into the oviduct. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play ... |
|
TMPH-02990
|
Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (His)
14 kDa antigen,Acr,16 kDa antigen,HSP 16.3
|
Mycobacterium bovis
|
Baculovirus Insect Cells
|
|
Acts as a chaperone. Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (His) is expressed in Baculovirus insect cells with C-9xHis tag. The predicted molecular weight is 18.1 kDa and the accession number is P0A5B8. |
|
TMPH-00662
|
Trigger factor Protein, E. coli O127:H6, Recombinant (His)
tig,PPIase,Trigger factor
|
E. coli
|
P. pastoris (Yeast)
|
|
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. |
|
TMPH-01803
|
NAP1L4 Protein, Human, Recombinant (His & Myc)
Nucleosome assembly protein 2,Nucleosome assembly protein 1-...
|
Human
|
E. coli
|
|
Acts as histone chaperone in nucleosome assembly. NAP1L4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q99733. |
|
TMPH-02851
|
PDIA2 Protein, Mouse, Recombinant (His & SUMO)
PDIp,Pdia2,Protein disulfide-isomerase A2
|
Mouse
|
E. coli
|
|
Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. |
|
TMPH-03010
|
EsxB Protein, Mycobacterium tuberculosis, Recombinant (His)
ESAT-6-like protein EsxB,10 kDa culture filtrate antigen CFP...
|
Mycobacterium tuberculosis
|
P. pastoris (Yeast)
|
|
A secreted protein. Acts as a strong host T-cell antigen. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm. Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA. |
|
TMPH-02502
|
LRPAP1 Protein, Mouse, Recombinant (His & Myc)
Heparin-binding protein 44,Alpha-2-macroglobulin receptor-as...
|
Mouse
|
Baculovirus Insect Cells
|
|
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. LRPAP1 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is P55302. |
|
TMPJ-01124
|
PDIA6 Protein, Human, Recombinant (His)
Thioredoxin Domain-Containing Protein 7,P5,ERP5,TXNDC7,Prote...
|
Human
|
HEK293 Cells
|
|
Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA... |
|
TMPH-03698
|
VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc)
Phosphoprotein,P,Protein M1
|
VSIV
|
E. coli
|
|
Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template. May act as a chaperone for newly synthesized free N protein, so-called N(0). Plays a role in virion assembly. VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is P04879. |
|
TMPJ-01087
|
TIM14 Protein, S. cerevisiae, Recombinant
Mitochondrial import inner membrane translocase subunit TIM1...
|
S. cerevisiae
|
E. coli
|
|
Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1). TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as p... |
|
TMPH-00094
|
HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
25.3 kDa heat shock protein, chloroplastic,HSP21,Heat shock ...
|
Arabidopsis thaliana
|
E. coli
|
|
Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.4 kDa and the accession number is P31170. |
|
TMPJ-00754
|
CRYAA Protein, Human, Recombinant (His)
Heat Shock Protein Beta-4,CRYA1,α-Crystallin A Chain,HSPB4,S...
|
Human
|
E. coli
|
|
Alpha-Crystallin A Chain (CRYAA) belongs to the small heat shock protein (HSP20) family and can be induced by heat shock. The expression of CRYAA is preferentially restricted to the lens cell. CRYAA may contribute to the transparency and refractive index of the lens. CRYAA has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Two additional functions of CRYAA are an autokinase activity and participation in the intracellular architecture. |
|
TMPH-03009
|
EsxB Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)
ESAT-6-like protein EsxB,esxB,10 kDa culture filtrate antige...
|
Mycobacterium tuberculosis
|
E. coli
|
|
A secreted protein. Acts as a strong host T-cell antigen. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm. Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA. EsxB Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 14.7 kDa and the accession number is P9WNK4. |
|
TMPH-00083
|
Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
ERD14,Dehydrin ERD14
|
Arabidopsis thaliana
|
E. coli
|
|
Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity. Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is P42763. |
|
TMPH-03073
|
TDX Protein, Japonica rice, Recombinant (His & Myc)
OsTrx26,Tetratricoredoxin,TPR repeat-containing thioredoxin ...
|
Rice
|
E. coli
|
|
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions and act as chaperone under heat shock. May interact with HSP70 proteins through the TPR repeats. TDX Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.0 kDa and the accession number is Q6ES52. |
|
TMPH-03721
|
IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His)
Small heat shock protein IbpA,16 kDa heat shock protein A,ib...
|
Yersinia pestis
|
E. coli
|
|
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent. |
|
TMPJ-01411
|
HSPB11 Protein, Human, Recombinant (His)
PP25,Placental Protein 25,Heat Shock Protein β-11,Heat Shock...
|
Human
|
E. coli
|
|
Heat Shock Protein β-11 (HSPB11) is a stress-responsive protein that is required to deal with proteotoxic stresses. HSPB11 is composed of an IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20 and is detected in placenta. HSPB11 has beeb shown to form oligomeric complexes and prevent the aggregation of in vitro denaturated aldolase and glyceraldehyde-3-phosphate dehydrogenase in accordance with the chaperone model of HSPB1 and HSPB5. HSPB11 overexpression protected a... |
|
TMPH-03705
|
NfuA Protein, Vibrio vulnificus, Recombinant
nfuA,Fe/S biogenesis protein NfuA
|
Vibrio vulnificus
|
E. coli
|
|
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, Vibrio vulnificus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.0 kDa and the accession number is Q8DDU2. |
|
TMPH-00621
|
NfuA Protein, E. coli, Recombinant (His)
Fe/S biogenesis protein NfuA,nfuA
|
E. coli
|
E. coli
|
|
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.1 kDa and the accession number is B1X760. |
|
TMPH-03746
|
NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated
Fe/S biogenesis protein NfuA,nfuA
|
ENT-Escherichia coli
|
E. coli
|
|
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 68.8 kDa and the accession number is B1X760. |
|
TMPY-03444
|
PFDN4 Protein, Human, Recombinant (His)
PFD4,prefoldin subunit 4,C1
|
Human
|
E. coli
|
|
PFDN4 is a member of the prefoldin beta subunit family. It is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. PFDN4 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. PFDN4 also binds to nascent polypeptide chain and ... |
|
TMPJ-00676
|
PPIH Protein, Human, Recombinant (His)
Peptidyl-Prolyl Cis-Trans Isomerase H,Rotamase H,PPIase H,Sm...
|
Human
|
E. coli
|
|
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the i... |
|
TMPY-03396
|
PFDN2 Protein, Human, Recombinant (His)
PFD2,prefoldin subunit 2
|
Human
|
E. coli
|
|
PFD2, also known as PFDN2, belongs to the prefoldin beta subunit family. PFD2 is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. PFD2 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. PFD2 also binds to a nascent pol... |
|
TMPH-01428
|
TRAP1 Protein, Human, Recombinant (GST)
TNFR-associated protein 1,Tumor necrosis factor type 1 recep...
|
Human
|
E. coli
|
|
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. TRAP1 Protein, Human, Recombinant (GST) is expressed in E. coli expressi... |
沪公网安备 31010602006700号