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Search Results for " β-endorphin "

Targets Recommended: Opioid Receptor

15

抑制剂 & 化合物

4

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T38193L	β-Endorphin (1-27) (human) acetate β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	β-Endorphin (1-27) (human) acetate 存在于大脑垂体和下丘脑中，具有镇痛活性。 β-Endorphin (1-27) (human) acetate 是一种阿片受体激动剂，对 μ-阿片受体和 δ-阿片受体具有较好的亲和力。
T35460	β-Endorphin (rat)
	β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. It is produced via piomelanocortin cleavage in the pituitary gland, hypothalamus, and in lymphocytes, then migrates to its sites of action which include plasma, gut, skin, placenta, cerebrospinal fluid, and cardiac tissues. β-EP induces concentration-dependent decreases in electrically stimulated contraction of the mouse vas deferens that can be reversed by the μ-opioid antagonist CTP and δ-opioid antagon...
TP1647	β-Endorphin, equine
	Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain. Endorphin Beta is produced in response to pain, exercise, and other forms of stress. Endorphin Beta belongs to a group of
TP1391	β-Endorphin, equine (TFA)
	β-Endorphin, equine (TFA) is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors.
T38193	β-Endorphin (1-27) (human) (trifluoroacetate salt)
	β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 1.1 and 5.7 nM, respectively) and induces chemotaxis of human monocytes in vitro when used at a concentration of 1 nM. Intracerebroventricular administration of β-endorphin (1-27) increases the latency to tail withdrawal in response to thermal stimulation in ...
T37478	Acetyl β-Endorphin (1-26) (human) (trifluoroacetate salt)
	Acetyl β-endorphin (1-26) is a neuropeptide found in rat hippocampus, brain stem, and pituitary. It is also present in the human hypothalamus, where it comprises approximately 4.9% of total β-endorphin peptides. Acetyl β-endorphin (1-26) is produced through posttranslational processing of β-endorphin and is processed similarly in rat and human hypothalamus. Levels of acetyl β-endorphin (1-26) increase in the rat pars intermedia and brain stem following chronic administration of haloperidol .
TP1508L	N-Acetyl-α-Endorphin acetate N-Acetyl-α-Endorphin acetate(88264-63-5 free base)	Others	Others
	N-Acetyl-α-Endorphin acetate(88264-63-5 free base) 是 N 末端乙酰化的 α-Endorphin。 α-内啡肽是一种内源性 opioid 肽。
T80693	β-Endorphin, rat β-Lipotropin 61-91
	β-Endorphin, rat (β-Lipotropin 61-91) 是一种在心血管调节中起作用的神经肽。该化合物能导致大鼠出现显著的持续性肌肉僵硬和静止，这种效应与紧张状态相似。
T76285	β-Endorphin (6-31), human β-EP (6-31), human	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	β-Endorphin是一种内源性阿片类神经肽，作为opioid receptor激动剂，主要与μ-阿片受体发生作用。该肽在中枢和周围神经系统特定神经元中表达，是人类体内三种内啡肽之一。β-Endorphin在减轻压力、维护生理平衡及调控神经系统的疼痛感知中发挥作用。
T80515	β-Endorphin (1-27) (human)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	β-Endorphin (1-27) (human) 是一种 opioid 拮抗剂，与 μ-、δ- 及 κ-阿片受体结合，其 Kis 分别为 5.31、6.17 及 39.82 nM。该化合物还能够抑制由 β-Endorphin 及 etorphine 引起的痛觉消失。
T8171	Glycyl-glutamine Glycyl-L-glutamine monohydrate,甘氨酰-L-谷氨酰胺一水合物,Glycyl-L-glutamine,Glycylglutamine	Others	Others
	Glycyl-glutamine (Glycyl-L-glutamine monohydrate) 是 β-内啡肽(1-31) 的内源拮抗剂，是β-endorphin 的酶裂解产品。它是一种比谷氨酰胺 (Gln) 稳定的活性神经肽。
TP1002L	γ-1-MSH, amide acetate (72629-65-3 free base) γ-1-MSH, amide acetate	Others	Others
	γ-1-MSH, amide acetate (72629-65-3 free base) 是 ACTH/β-内啡肽 (β-EP) 前体蛋白 N 末端区域的一种推定激素，RIA 使用抗 γ-3-MSH 抗血清对产生 ACTH 的小鼠进行了研究垂体肿瘤细胞，AtT-20/D16v。
T83484	[Tyr0] Corticotropin Releasing Factor, ovine
	[Tyr0] Corticotropin Releasing Factor, ovine 是从绵羊分离的促肾上腺皮质激素释放因子/激素。该因子（CRF）为下丘脑激素，能激发促肾上腺皮质激素（ACTH）及β-内啡肽的释放。
TP2243	Dynorphin (2-17), amide, porcine	Others	Others
	Dynorphins are a class of opioid peptides that arise from the precursor protein prodynorphin. When prodynorphin is cleaved during processing by proprotein convertase 2 (PC2), multiple active peptides are released: dynorphin A, dynorphin B, and α/β-neo-end
T76361	[DPro5] Corticotropin Releasing Factor, human, rat
	[DPro5] Corticotropin Releasing Factor, human, rat 是人类和大鼠促肾上腺皮质激素释放因子/激素 R2 的选择性激动剂。作为一种下丘脑激素，促肾上腺皮质激素释放因子 (CRF) 能够促进肾上腺皮质激素 (ACTH) 和 β-内啡肽的分泌。值得注意的是，[DPro5] Corticotropin Releasing Factor, human, rat 并不触发典型的焦虑反应，而是能调控大鼠的学习与记忆过程。

化合物

β-Endorphin (1-27) (human) acetate

Cat.No: T38193L

Synonym: β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)

Target: Opioid Receptor

β-Endorphin (rat)

Cat.No: T35460

β-Endorphin, equine

Cat.No: TP1647

β-Endorphin, equine (TFA)

Cat.No: TP1391

β-Endorphin (1-27) (human) (trifluoroacetate salt)

Cat.No: T38193

Acetyl β-Endorphin (1-26) (human) (trifluoroacetate salt)

Cat.No: T37478

N-Acetyl-α-Endorphin acetate

Cat.No: TP1508L

Synonym: N-Acetyl-α-Endorphin acetate(88264-63-5 free base)

Target: Others

β-Endorphin, rat

Cat.No: T80693

Synonym: β-Lipotropin 61-91

β-Endorphin (6-31), human

Cat.No: T76285

Synonym: β-EP (6-31), human

Target: Opioid Receptor

β-Endorphin (1-27) (human)

Cat.No: T80515

Target: Opioid Receptor

Glycyl-glutamine

Cat.No: T8171

Synonym: Glycyl-L-glutamine monohydrate,甘氨酰-L-谷氨酰胺一水合物,Glycyl-L-glutamine,Glycylglutamine

Target: Others

γ-1-MSH, amide acetate (72629-65-3 free base)

Cat.No: TP1002L

Synonym: γ-1-MSH, amide acetate

Target: Others

[Tyr0] Corticotropin Releasing Factor, ovine

Cat.No: T83484

Dynorphin (2-17), amide, porcine

Cat.No: TP2243

Target: Others

[DPro5] Corticotropin Releasing Factor, human, rat

Cat.No: T76361

Cat. No.	Product Name	Target	Signaling Pathways
T13433	β-Endorphin, human	Others	Others
	β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus,and is an agonist of opioid receptor.
T76027	β-Endorphin, equine TFA	Others	Others
	β-Endorphin, equine TFA，是具备强效亲和力于μ和δ阿片受体(μ/δ opioid receptors)的内源性阿片类多肽，主要功能包括止痛。
T3896	Shanzhiside methyl ester 三栀子甙甲酯,山芝皂苷甲酯	Glucagon Receptor	GPCR/G Protein
	Shanzhiside methyl ester 是一种小分子胰高血糖素样肽 1 受体激动剂，分离自轮状乳杆菌，能够诱导抗异常性痛觉耐受。
T2889	Isoferulic acid Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸	Influenza Virus; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物，有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体，增强 β-内啡肽的分泌并增加体外葡萄糖的使用。

天然产物

β-Endorphin, human

Cat.No: T13433

Target: Others

β-Endorphin, equine TFA

Cat.No: T76027

Target: Others

Shanzhiside methyl ester

Cat.No: T3896

Synonym: 三栀子甙甲酯,山芝皂苷甲酯

Target: Glucagon Receptor

Isoferulic acid

Cat.No: T2889

Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸

Target: Influenza Virus, Adrenergic Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00851	IDE Protein, Human, Recombinant (His) Insulysin,Insulinase,Insulin-Degrading Enzyme,IDE,Abeta-Degr...	Human	HEK293 Cells
	Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted...

重组蛋白

IDE Protein, Human, Recombinant (His)

Cat.No: TMPJ-00851

Species: Human

Expression System: HEK293 Cells

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