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Search Results for " thrombosis "

Targets Recommended: P2Y Receptor

63

抑制剂 & 化合物

6

天然产物

1

化合物库

7

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L6750	活血化瘀中药单体库		580 compounds
	580种来源于常见活血化瘀中药的单体化合物，是药物开发、药理研究等领域的有效工具。

化合物库

活血化瘀中药单体库

Cat.No: L6750

Compounds: 580

Cat. No.	Product Name	Target	Signaling Pathways
T4132	BPTU BMS-646786	P2Y Receptor	GPCR/G Protein; Neuroscience
	BPTU (BMS-646786) 是一种非核苷酸类P2Y1受体变构拮抗剂，能够阻断位于胃肠道神经肌肉接头的 P2Y1受体，具有抗血栓活性。
T2629	UNC2881	TAM Receptor	Tyrosine Kinase/Adaptors
	UNC2881 是一种特异性Mer 激酶抑制剂，可抑制稳态的Mer 激酶磷酸化，其IC50=22 nM。
T1891	NSC 405020	MMP	Proteases/Proteasome
	NSC 405020 是一种 MT1-MMP 的非催化抑制剂，可特异地靶向 MT1-MMP 的 PEX 结构域，不会抑制 MT1-MMP 和 MMP-2的催化活性。
T4978	Sarpogrelate hydrochloride 盐酸沙格雷酯,MCI-9042	5-HT Receptor	GPCR/G Protein; Neuroscience
	Sarpogrelate hydrochloride (MCI-9042) 是一种选择性5-HT2R 拮抗剂，可用于研究与血栓形成有关的血管疾病，对 5-HT2A、5-HT2B 和 5-HT2C 受体的pKi 值分别为 8.52、6.57 和 7.43。
T4570	Pipobroman Vercyte,A-8103,Amedel,哌泊溴烷	Others; DNA Alkylator/Crosslinker	DNA Damage/DNA Repair; Others
	Pipobroman (Vercyte) 是一种烷基化剂，是哌嗪的溴化衍生物。它通过抑制 DNA 和 RNA 聚合酶或减少嘧啶核苷酸掺入 DNA 发挥其作用。它在真性红细胞增多症和原发性血小板增多症中具有良好的临床活性，可用于癌症研究。
T12870	SCH79797 dihydrochloride	Apoptosis; Others; Protease-activated Receptor	Apoptosis; GPCR/G Protein; Others
	SCH79797 dihydrochloride 是一种有效的特异性蛋白酶激活受体 1 (PAR1) 拮抗剂，IC50 为 70 nM，Ki 为 35 nM。SCH79797 dihydrochloride 具有抗增殖和促凋亡作用。
T0005	Aspirin 阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA	Mitophagy; Virus Protease; COX; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Aspirin (Acetylsalicylic Acid) 是一种选择性 COX 抑制剂，具有多种药理活性。它是组蛋白去乙酰化酶抑制剂，可上调细胞周期阻滞蛋白 p21，抑制携带 COX-1 的卵巢 Y 细胞。它还抑制 HUVEC 和新生大鼠心室心肌细胞中 COX-2 的表达，分别减少 PG 的产生和 ERK 和 NF-KB 的下调。
T80792	WAY-639228	Others	Others
	WAY-639228-A 具有潜在的抗血栓和抗凝活性，可用于研究脑血栓。
T35161	Xemilofiban SC-54684A,SC54684A,SC 54684A	Others	Others
	Xemilofiban (SC 54684A) 可中断血小板聚集，可促进血栓形成，可用于研究不稳定型心绞痛。
T34280	Regrelor disodium INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589	P2Y Receptor	GPCR/G Protein; Neuroscience
	Regrelor disodium (INS 50589) 是一种 p2y12 受体拮抗剂，可预防血栓形成，可有效抑制血管平滑肌细胞收缩，抑制细胞增殖，减少炎症。
T22787	FPL 55712	LTR	Immunology/Inflammation
	FPL 55712 是白三烯受体和 SRS-A 拮抗剂，抑制支气管收缩，可用于研究哮喘和冠状动脉血栓。
T37299	L-Palmitoylcarnitine chloride Palmitoyl-L-carnitine chloride	ATPase	Membrane transporter/Ion channel
	L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物，具有抗血栓形成的作用，通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵，抑制 FeCl 3诱导的动脉血栓形成，减轻了短暂性大脑中动脉闭塞（tMCAO）小鼠模型的脑内血栓形成和炎症。
T27630	Isbogrel CV4151,CV-4151,CV 4151	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Isbogrel (CV4151)是一种小分子血栓素A2合成酶(TXA2 synthase)抑制剂，可用来研究心律失常、短暂性脑缺血发作和血栓形成。
T68022L	Sulotroban potassium BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base)	PPAR	DNA Damage/DNA Repair; Metabolism
	Sulotroban potassium 是一种小分子血栓素A2受体（TXA2R）拮抗剂，可用于研究心肌梗塞和血栓形成。
T24567	Octimibate Octimibato	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Octimibate (Octimibato) 是一种非前列腺素类血小板聚集抑制剂和环前列腺素激动剂。Octimibate 可用于治疗心血管疾病，可用于研究动脉粥样硬化和血栓形成。
T68078	Gantofiban	Integrin	Cytoskeletal Signaling
	Gantofiban是一种糖蛋白 IIb/IIIa（GP IIb/IIIa）拮抗剂，可用于治疗心血管疾病，可用于研究血栓形成。
T71641	BMS-593214	Others	Others
	BMS-593214 是一种活性位点定向因子 (F)VIIa 抑制剂。BMS-593214 具有抗血栓和抗出血特性。BMS-593214 是人 FVIIa 的直接竞争性抑制，也是 VIIa 激活底物 FX 的非竞争性抑制剂。BMS-593214 预防电诱导颈动脉血栓形成 (AT)、线诱导腔静脉血栓形成 (VT)。
T3469	PCI-27483 PCI27483	Others	Others
	PCI-27483 是一种FVIIa/tissue factor 抑制剂，具有抗肿瘤的作用。
T77687	3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one	Others	Others
	3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one 在人结肠癌细胞系中显示出抗肿瘤活性，可能用于防治血栓。
T68086	Imitrodast	Thrombin	Proteases/Proteasome
	Imitrodast是一种小分子血栓素A2合成酶（TXA2 synthase）抑制剂，可用于治疗免疫系统疾病、呼吸系统疾病和心血管疾病，可用于研究动脉血栓形成、哮喘和冠状血管痉挛。
T29215	Zifaxaban TY 602,TY602,TY-602	Factor Xa	Metabolism
	Zifaxaban (TY-602) 是一种具有口服活性、竞争性和选择性的 Xa 因子 (FXa) 抑制剂，对人 FXa 的 IC50 为 11.1 nM。Zifaxaban 的亲和力很高，比其他丝氨酸蛋白酶高 10000 倍以上。Zifaxaban 可用于研究动脉和静脉血栓形成。
T6952	Prasugrel Hydrochloride LY 640315,PCR 4099 (hydrochloride),盐酸普拉格雷,Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl	P2Y Receptor	GPCR/G Protein; Neuroscience
	Prasugrel Hydrochloride (LY 640315 Hydrochloride) 是一种噻吩吡啶和前药，是一种可口服的P2Y12受体拮抗剂，抑制 ADP 诱导的血小板聚集，用于预防急性冠状动脉综合征患者的血栓形成、不稳定型心绞痛和心肌梗塞，以及接受经皮冠状动脉介入治疗的患者。
T77442	Glenzocimab ACT017	Others	Others
	Glenzocimab (ACT017) 是人源化抗 GPVI 单克隆抗体的 Fab 片段。Glenzocimab 在缺血性卒中模型对胶原诱导的血小板聚集显示出抑制作用。Glenzocimab 具有研究急性缺血性脑卒中和脑血栓。
T0230	Prasugrel LY640315,CS-747,普拉格雷,PCR 4099	P2Y Receptor	GPCR/G Protein; Neuroscience
	Prasugrel (CS-747) 是一种噻吩吡啶和前药，是一种可口服的 P2Y12受体拮抗剂，抑制 ADP 诱导的血小板聚集，用于预防急性冠状动脉综合征患者的血栓形成、不稳定型心绞痛和心肌梗塞，以及接受经皮冠状动脉介入治疗的患者。
T77124	Osocimab BAY 1213790	FXR	Metabolism
	Osocimab (BAY 1213790) 是一种高效的抗 FXIa 抗体，Ki 值为 2.4 nM，EC50 值为 0.2 nM。Osocimab 可能通过 FXI 抑制降低血栓形成。Osocimab 常被当作 XI 因子抑制剂，对凝血酶生成有抑制作用，有抗凝血作用，可用于研究血栓栓塞性疾病。
T0815L	Warfarin sodium	Others	Others
	Warfarin sodium 是一种抗凝血剂，通过抑制维生素 K 依赖性凝血因子的合成起作用。华法林适用于预防和/或治疗静脉血栓形成及其延伸、肺栓塞和房颤栓塞。它还用作预防心肌梗塞后全身性栓塞的辅助剂。华法林也用作杀鼠剂。
T4341	Betrixaban 贝曲西班,PRT054021	Factor Xa	Metabolism
	Betrixaban (PRT054021) 是一种口服具有活力的选择性factor Xa(fXa) 抑制剂，IC50=1.5 nM。
T31206	Darexaban YM 150,Darexaban, Tanexaban,YM150	Factor Xa	Metabolism
	Darexaban (Tanexaban, YM-150) 是选择性的、口服具有活力的 Xa 因子 (FXa) 抑制剂，IC50=54.6 nM。它对其他相关丝氨酸蛋白酶(如胰蛋白酶、凝血酶和激肽释放酶)具有高选择性。它具有抗凝和抗血栓形成作用。
T68002	Naroparcil	Thrombin	Proteases/Proteasome
	Naroparcil 是一种可口服的硫代苷类化合物，是一种 4-甲基伞形 β-D-木糖苷类似物，在静脉血栓形成（颈静脉）的Wessler淤滞模型中显示出抗血栓形成作用。Naroparcil 增强了凝血酶/肝素辅因子II复合物的形成，诱导了处理兔血浆中硫酸皮肤素样物质的出现，但减少了与（125I）-人α-凝血酶孵育的血浆中的凝血酶/抗凝血酶III复合物的形成。
T4980	Betrixaban maleate	Factor Xa	Metabolism
	Betrixaban maleate 是一种非维生素 K 口服抗凝剂，其作用是由 Xa 因子的竞争性和可逆抑制作用驱动的。
T24743	RU-505 RU 505,RU505	Others	Others
	RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.
T70510	CVS-1123	Others	Others
	CVS-1123 is a direct thrombin inhibitor, preventing occlusive arterial and venous thrombosis in a canine model of vascular injury.
T27202	DPC-423 DPC-423 Free	Others	Others
	DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.
T27336	Flovagatran sodium TGN255,TGN-255,TGN 255	Others	Others
	Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.
T71472	LN6023	Others	Others
	LN6023 is a ACKR3/CXCR7 Superagonist for Platelet Degranulation Modulation. LN6023 effectively reduced P-selectin expression by up to 97%, suggesting to be a potential candidate for the treatment of platelet-mediated thrombosis.
T28477	PZ-128 PZ 128
	PZ-128, a PAR1 antagonist, is used potentially for the treatment of thrombosis.
T26725	AZD-9684 AZD9684,AZD 9684	Others	Others
	AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.
T70681	G-4120	Others	Others
	G-4120 is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis.
T82888	Bibapcitide
	Bibapcitide为含26个氨基酸残基的多肽，表现出抗凝血功能。
T79188	BT100	Integrin	Cytoskeletal Signaling
	BT100 为一核酸适配体，能够抑制血管性血友病因子(von Willebrand factor, VWF)与血小板糖蛋白GPIb之间的结合，旨在预防动脉血栓的形成。
T68761	Cloricromen hydrochloride Cloricromene hydrochloride,Cloricromen hydrochloride	Others	Others
	Cloricromen hydrochloride，一种血小板聚集抑制剂，能够抑制人体及实验性血栓形成中的血小板聚集。
T82360	FXIIa-IN-2	Others	Others
	XIIa-IN-1-IN-2（Compound 21）为一种高效的Factor XIIa抑制剂，具有Kiapp为62.2 nM。该化合物适用于血栓形成的研究领域。
T62633	NTPDase-IN-3	Others	Others
	NTPDase-IN-3 (Compound 5e) 是一种 NTPDase 抑制剂，IC50值分别为 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), 1.07 μM (NTPDase2)。NTPDase-IN-3 可用于癌症和血栓形成的研究。
T80095	D-Pro-Phe-Arg-Chloromethylketone	Factor Xa	Metabolism
	D-Pro-Phe-Arg-Chloromethylketone是一种抑制剂，它针对凝血因子XII (coagulation factor XII) 和血浆激肽释放酶 (kallikrein)，在血栓形成和炎症过程中具有关键作用。
T73855	Thromboxane B1	Others	Others
	Thromboxane B1 (TXB1) 是TXB家族中的一员，属于类花生酸脂质家族。该家族因参与血栓形成而得名。
T82361	FXIIa-IN-1	Others	Others
	XIIa-IN-1-IN-3（Compound 22）作为一种Factor XIIa抑制剂，其Kiapp值为97.8 nM。该化合物主要应用于血栓形成的研究。
T64250	Desirudin	Others	Others
	Desirudin (CGP 39393) 是一种凝血酶 (thrombin) 抑制剂，能够抑制血栓形成和静脉淤血性血栓形成。Desirudin 能够用于研究血小板减少症或血小板功能障碍相关。
T63596	PI3KC2α-IN-2	Others	Others
	PI3KC2α-IN-2 是选择性的、有效的 PI3KC2α 抑制剂，IC50 值为 121 nM，能够与 PI3KC2α 的 ATP 结合位点相互作用。PI3KC2α-IN-2 能够用于研究血栓形成、糖尿病和癌症。
T36553	Thrombin Receptor Peptide Ligand (trifluoroacetate salt)	Others	Others
	Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide in vitro when used at a concentration of 32 μM but does not affect platelet aggregation induced by ADP or collagen. It also inhibits thrombin- and TRAP-induced proliferation of vascular smooth muscle cells (VSMCs). Thrombin receptor peptide ligand (100 μmol/kg bolus, i.v...
T75518	Galactofucan	Others	Others
	Galactofucan (Fucogalactan) 是一种硫酸多糖。Galactofucan 可以从棕色海藻 Saccharina longicruris 中提取，具有抗凝血、抗肿瘤、抗血栓形成、抗炎、抗病毒等特性。Galactofucan 对 HSV-1和 HSV-2具有抗病毒活性，IC50值分别为 0.76 和 1.34 µg/mL 。Galactofucan 可用于癌症和炎症的研究。

化合物

Cat.No: T4132

Synonym: BMS-646786

Target: P2Y Receptor

Cat.No: T2629

Target: TAM Receptor

Cat.No: T1891

Target: MMP

Sarpogrelate hydrochloride

Cat.No: T4978

Synonym: 盐酸沙格雷酯,MCI-9042

Target: 5-HT Receptor

Cat.No: T4570

Synonym: Vercyte,A-8103,Amedel,哌泊溴烷

Target: Others, DNA Alkylator/Crosslinker

SCH79797 dihydrochloride

Cat.No: T12870

Target: Apoptosis, Others, Protease-activated Receptor

Cat.No: T0005

Synonym: 阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA

Target: Mitophagy, Virus Protease, COX, Autophagy

Cat.No: T80792

Target: Others

Cat.No: T35161

Synonym: SC-54684A,SC54684A,SC 54684A

Target: Others

Regrelor disodium

Cat.No: T34280

Synonym: INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589

Target: P2Y Receptor

Cat.No: T22787

Target: LTR

L-Palmitoylcarnitine chloride

Cat.No: T37299

Synonym: Palmitoyl-L-carnitine chloride

Target: ATPase

Cat.No: T27630

Synonym: CV4151,CV-4151,CV 4151

Target: Prostaglandin Receptor

Sulotroban potassium

Cat.No: T68022L

Synonym: BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base)

Target: PPAR

Cat.No: T24567

Synonym: Octimibato

Target: Prostaglandin Receptor

Cat.No: T68078

Target: Integrin

Cat.No: T71641

Target: Others

Cat.No: T3469

Synonym: PCI27483

Target: Others

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

Cat.No: T77687

Target: Others

Cat.No: T68086

Target: Thrombin

Cat.No: T29215

Synonym: TY 602,TY602,TY-602

Target: Factor Xa

Prasugrel Hydrochloride

Cat.No: T6952

Synonym: LY 640315,PCR 4099 (hydrochloride),盐酸普拉格雷,Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl

Target: P2Y Receptor

Cat.No: T77442

Synonym: ACT017

Target: Others

Cat.No: T0230

Synonym: LY640315,CS-747,普拉格雷,PCR 4099

Target: P2Y Receptor

Cat.No: T77124

Synonym: BAY 1213790

Target: FXR

Warfarin sodium

Cat.No: T0815L

Target: Others

Cat.No: T4341

Synonym: 贝曲西班,PRT054021

Target: Factor Xa

Cat.No: T31206

Synonym: YM 150,Darexaban, Tanexaban,YM150

Target: Factor Xa

Cat.No: T68002

Target: Thrombin

Betrixaban maleate

Cat.No: T4980

Target: Factor Xa

Cat.No: T24743

Synonym: RU 505,RU505

Target: Others

Cat.No: T70510

Target: Others

Cat.No: T27202

Synonym: DPC-423 Free

Target: Others

Flovagatran sodium

Cat.No: T27336

Synonym: TGN255,TGN-255,TGN 255

Target: Others

Cat.No: T71472

Target: Others

Cat.No: T28477

Synonym: PZ 128

Cat.No: T26725

Synonym: AZD9684,AZD 9684

Target: Others

Cat.No: T70681

Target: Others

Cat.No: T82888

Cat.No: T79188

Target: Integrin

Cloricromen hydrochloride

Cat.No: T68761

Synonym: Cloricromene hydrochloride,Cloricromen hydrochloride

Target: Others

Cat.No: T82360

Target: Others

Cat.No: T62633

Target: Others

D-Pro-Phe-Arg-Chloromethylketone

Cat.No: T80095

Target: Factor Xa

Cat.No: T73855

Target: Others

Cat.No: T82361

Target: Others

Cat.No: T64250

Target: Others

Cat.No: T63596

Target: Others

Thrombin Receptor Peptide Ligand (trifluoroacetate salt)

Cat.No: T36553

Target: Others

Cat.No: T75518

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4S0592	Toddalolactone (+)-Toddalolactone,飞龙掌血内酯,毛两面针素	PAI-1	Metabolism
	Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分，能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性， IC50=37.31 μM。
T2223	Kinetin 激动素,6-Furfuryladenine,6-糠氨基嘌呤,N6-Furfuryladenine	Others	Others
	Kinetin (N6-Furfuryladenine) 是 N6-取代腺嘌呤衍生物细胞分裂素家族成员，其中细胞分裂素是一种参与细胞分裂、分化等生理过程的植物生长激素。它具有抗衰老活性。
T2S0007	Ferulic acid sodium 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate	FGFR; Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite	Angiogenesis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
	Ferulic acid sodium (Sodium ferulic) 是新型的成纤维细胞生长因子受体 1 (FGFR1) 抑制剂。它对于FGFR1和FGFR2的IC50分别为 3.78 and 12.5 μM。
TN1238	3,4-O-Isopropylidene-shikimic acid 3,4-O-异亚丙基莽草酸,3,4-O-Isopropylidene shikimic acid	NOS; NO Synthase	Immunology/Inflammation
	3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) 是一种从Hypericum wightianum 中提取得到的天然产物。它具有抗炎症和抗氧化作用。
T15248	Estetrol Donesta	Estrogen Receptor/ERR; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estetrol(Donesta) 是可口服且具有选择性核雌激素受体 (estrogen receptor) 调节剂,是一种在怀孕期间由人类胎儿肝脏合成的天然雌激素。Estetrol 对子宫内膜或中枢神经系统有作用，但对乳房有拮抗作用。Estetrol 在低浓度时可能有助于降低血栓形成。Estetrol 可用于缓解更年期症状。
TN1953	Morusinol 桑根皮醇,桑树醇	ERK; MEK; Autophagy; Ras	Autophagy; GPCR/G Protein; MAPK
	Morusinol 是从桑树根皮中提取出的类黄酮。 Morusinol 具有抗血小板和抗癌活性，在体内抑制动脉血栓形成，通过诱导自噬、G2/M 细胞周期阻滞、抑制细胞侵袭和迁移以及靶向 Ras/MEK/ERK 通路发挥抗肿瘤活性。

天然产物

Cat.No: T4S0592

Synonym: (+)-Toddalolactone,飞龙掌血内酯,毛两面针素

Target: PAI-1

Cat.No: T2223

Synonym: 激动素,6-Furfuryladenine,6-糠氨基嘌呤,N6-Furfuryladenine

Target: Others

Ferulic acid sodium

Cat.No: T2S0007

Synonym: 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate

Target: FGFR, Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite

3,4-O-Isopropylidene-shikimic acid

Cat.No: TN1238

Synonym: 3,4-O-异亚丙基莽草酸,3,4-O-Isopropylidene shikimic acid

Target: NOS, NO Synthase

Cat.No: T15248

Synonym: Donesta

Target: Estrogen Receptor/ERR, Endogenous Metabolite

Cat.No: TN1953

Synonym: 桑根皮醇,桑树醇

Target: ERK, MEK, Autophagy, Ras

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01075	Von Willebrand Factor/vWF Protein, Human, Recombinant (His) von Willebrand factor,VWD,F8VWF	Human	CHO Cells
	Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thr...
TMPK-00878	FOLR3 Protein, Human, Recombinant (His) FR-γ,Folate receptor 3,FR-gamma,FR-G	Human	HEK293 Cells
	Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures.
TMPK-00993	Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His) Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Coagulation Factor I...	Canine	HEK293 Cells
	Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
TMPJ-01383	Serpin A10 Protein, Human, Recombinant (His) PZI,Protein Z-Dependent Protease Inhibitor,Serpin A10,ZPI,PZ...	Human	HEK293 Cells
	Serpin A10 is a secreted protein that belongs to the serpin family. It is predominantly expressed in the liver and secreted in the plasma. Its phosphorylation sites are present in the extracelllular medium. It inhibits factors Xa and XIa of the coagulation cascade in the presence of protein Z, calcium, and phospholipid. Mutations in SERPINA10 are associated with venous thrombosis.
TMPJ-00682	CD39L1 Protein, Mouse, Recombinant (His) Ectonucleoside triphosphate diphosphohydrolase 2,Entpd2	Mouse	HEK293 Cells
	CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by p...
TMPJ-00857	Thrombomodulin Protein, Mouse, Recombinant (His) Fetomodulin,Thbd,BDCA-3,Thrombomodulin,CD141,TM	Mouse	HEK293 Cells
	Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits ...
TMPY-00540	ANXA5 Protein annexin A5
	The placental anticoagulant protein Annexin A5 (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintaining blood fluidity of the placenta. Annexin A5 (ANXA5) is a protein abundantly expressed in normal placenta where it contributes to the healthy outcome of a pregnancy. Lower ANXA5 levels have been observed in M2/ANXA5 haplotype carrying chorion. The association found between the...

重组蛋白

Von Willebrand Factor/vWF Protein, Human, Recombinant (His)

Cat.No: TMPY-01075

Species: Human

Expression System: CHO Cells

FOLR3 Protein, Human, Recombinant (His)

Cat.No: TMPK-00878

Species: Human

Expression System: HEK293 Cells

Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)

Cat.No: TMPK-00993

Species: Canine

Expression System: HEK293 Cells

Serpin A10 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01383

Species: Human

Expression System: HEK293 Cells

CD39L1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00682

Species: Mouse

Expression System: HEK293 Cells

Thrombomodulin Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00857

Species: Mouse

Expression System: HEK293 Cells

Cat.No: TMPY-00540

Expression System:

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0040	Palmitoyl L-Carnitine-d3 Hydrochloride
	Palmitoyl L-Carnitine-d3 Hydrochloride 是 Palmitoyl L-Carnitine Hydrochloride 的氘代化合物。Palmitoyl L-Carnitine Hydrochloride 的 CAS 号为 18877-64-0。L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物，具有抗血栓形成的作用，通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵，抑制 FeCl 3诱导的动脉血栓形成，减轻了短暂性大脑中动脉闭塞（tMCAO）小鼠模型的脑内血栓形成和炎症。

同位素标记化合物

Palmitoyl L-Carnitine-d3 Hydrochloride

Cat.No: TMID-0040

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