6186
122
6
15
20
Cat. No. | Product Name | ||
---|---|---|---|
L9410 | 共价抑制剂库 | 1920 compounds | |
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发; | |||
L7300 | 钾通道分子库 | 152 compounds | |
152 种钾通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6150 | 天然产物共价化合物库 | 583 compounds | |
提供产品的生物学信息和药物学信息,为筛选提供理论方向和研究基础; | |||
L6130 | 萜类天然产物库 | 622 compounds | |
622 种萜类天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6110 | 生物碱类天然产物库 | 500 compounds | |
500 种生物碱类天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L7110 | 抗高血压化合物库 | 678 compounds | |
678 种高血压相关的小分子,用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19059 |
Solvent Yellow 93
|
Others | Others |
Solvent Yellow 93 是偶氮甲胺染料,可用作调色剂的着色剂。 | |||
T8734 |
Choline
|
Others | Others |
Choline hydroxide 是一种普遍存在的水溶性营养素,通常与 B 族维生素有关。 | |||
T2178 |
AMI5
AMI 5,Eosin Y Disodium,AMI-5 |
Others | Others |
AMI5 (Eosin Y Disodium) 是一种具有可溶性的酸性红色染料分子。它常用于机合成中的光氧化还原催化剂。 | |||
T1050 |
Prazosin hydrochloride
Prazosin hydrochloride,哌唑嗪盐酸盐,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,盐酸哌唑嗪,Minipress |
Potassium Channel; MRP; Adrenergic Receptor; ABC; Autophagy | Autophagy; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience |
Prazosin hydrochloride (Vasoflex) 是一种选择性肾上腺素能 α-1 拮抗剂,可降低外周阻力并放松血管平滑肌。 它可用于研究高血压和酒精使用障碍。 它是一种合成哌嗪衍生物,具有降压抗肾上腺素能特性。它抑制有机阳离子转运蛋白 OCT-1 和 OCT-3,IC50分别为 1.8 和 13 μM 。 | |||
T76173 |
Inorganic pyrophosphatase
|
Others | Others |
Inorganic pyrophosphatase (PPase) 无机焦磷酸酶可将焦磷酸盐 (PPi) 转化为磷酸盐。Inorganic pyrophosphatase 是 RNA 体外转录反应的重要组成部分,常用于生化研究。Inorganic pyrophosphatase 是驱动细胞过程,如核酸和蛋白质合成的关键。 | |||
T1380 |
Alodan
Cyclodan,Nodon,冰片丹,Chlorbicyclen |
Others | Others |
Alodan (Nodon) 是一种有机氯化物杀虫剂。 | |||
T9038 |
Diethylamine hydrochloride
二乙胺盐酸盐,METHYLTHIONINIUM CHLORIDE |
Others | Others |
Diethylamine hydrochloride (METHYLTHIONINIUM CHLORIDE) 用于有机合成。 | |||
T20856 |
Dicamba
Dianat,麦草畏,Mediben,Banlen,Banvel |
Others | Others |
Dicamba (Banvel) 是一种氯化有机除草剂。 Dicamba 可用于防治阔叶杂草。 | |||
T0526 |
2-Amino-5-nitrobenzophenone
|
Others | Others |
2-Amino-5-nitrobenzophenone 用作工业和有机中间体。 | |||
T9438 |
2,3,4-Trifluoro-5-Nitro-Benzoic Acid
|
Others | Others |
2,3,4-Trifluoro-5-Nitro-Benzoic Acid 是有机合成中有用的中间体。它已被用于研究氟取代对有机分子反应性的影响,还被用于研究硝基取代对有机分子反应性的影响。 | |||
T9895 |
1-Phenyloctane
|
Others | Others |
1-Phenyloctane 可增强石墨烯在有机溶剂中的液相剥离。 | |||
T0661 |
Dimethylsulfamoyl chloride
|
Others | Others |
Dimethylsulfamoyl chloride(DMSC)是一种有机硫化合物,用于有机合成和实验室试剂。 | |||
T22380 |
Nor-benzetimide
3-苯基-[3,4-联哌啶]-2,6-二酮 |
Others; AChR | Neuroscience; Others |
Norbenzetimide 是 Benzetimide 的主要代谢产物。Benzetimide 是一种mAChR 拮抗剂,具有抗胆碱能活性。 | |||
T3331 |
(1R,2R)-Trans-N-Boc-1,2-Cyclohexanediamine
(1R,2R)-反式-N-Boc-1,2-环己二胺,trans-N-Boc-1,2-diaminocyclohexane,N-Boc-trans-1,2-diaminocyclohexane |
Others | Others |
(1R,2R)-Trans-N-Boc-1,2-Cyclohexanediamine (N-Boc-trans-1,2-diaminocyclohexane) 是有机合成的中间体。 | |||
T3994 |
Verinurad
RDEA3170,维立诺雷 |
OAT | Membrane transporter/Ion channel |
Verinurad (RDEA3170) 是一种有效的、特异性的URAT1抑制剂,IC50为 25 nM。 | |||
T0340 |
Bisoctrizole
Tinosorb M,UV-360,Milestab-360,紫外光吸收剂UV-360,Tinuvin-360 |
Others | Others |
Bisoctrizole (Tinosorb M) 是广谱紫外线吸收剂,能够吸收UVB 和UVA 射线,并反射和散射紫外线。 | |||
T5903 |
Sitagliptin Intermediate 2
|
Others | Others |
Sitagliptin Intermediate 2 是有一种有用的有机化合物,已被用于生命科学相关研究。 | |||
T0698 |
Dioxybenzone
UV-24,二羟苯宗,Benzophenone-8,2,2'-Dihydroxy-4-methoxybenzophenone,Dioxybenzon,Cyasorb UV 24,Advastab 47 |
Others | Others |
Dioxybenzone (Benzophenone-8) 是一种能够阻断 UVB 和短波 UVA 紫外线照射的有机试剂。 | |||
T16126 |
Monepantel
AAD1566,PPL-1 |
AChR | Neuroscience |
Monepantel (AAD1566) 是一种有机驱虫剂,也是来自蛔虫和食管造口的烟碱乙酰胆碱受体拮抗剂,广泛用于农牧业除虫。 | |||
T124010 |
Dieckol
|
Others | Others |
Dieckol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124010。 | |||
T67910 |
2,4,5-Trichlorobenzenesulfonyl chloride
|
Others | Others |
2,4,5-Trichlorobenzenesulfonyl chloride (TCBSC) 是合成各种有机化合物(如胺、醇和羧酸)的通用构件。 | |||
T16539 |
Piperazine citrate
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Piperazine citrate 是一种六元环化合物,有驱虫的作用。 | |||
T131305 |
Compound N027-0014
|
Others | Others |
Compound N027-0014 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131305。 | |||
T2152 |
Dibutyl carbonate
|
Others | Others |
Dibutyl carbonate 用作中间体 | |||
T5651 |
Phenyl benzoate
|
Others | Others |
Phenyl benzoate 是苯酚与苯甲酸缩合而成的苯甲酸酯,是重要的有机合成中间体。 | |||
T131180 |
Compound N070-0004
|
Others | Others |
Compound N070-0004 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131180。 | |||
TPL0023 |
(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid
|
Others | Others |
(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid 是有一种有用的有机化合物,已被用于生命科学相关研究。 | |||
T131299 |
Compound N032-0004
|
Others | Others |
Compound N032-0004 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131299。 | |||
T131237 |
Compound N051-0050
|
Others | Others |
Compound N051-0050 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131237。 | |||
T131232 |
Compound N051-0055
|
Others | Others |
Compound N051-0055 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131232。 | |||
T131149 |
Compound N105-0030
|
Others | Others |
Compound N105-0030 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131149。 | |||
T131294 |
Compound N034-0005
|
Others | Others |
Compound N034-0005 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131294。 | |||
T131732 |
Compound AC-542/20643006
|
Others | Others |
Compound AC-542/20643006 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131732。 | |||
T64322 |
4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester
|
Others | Others |
4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester 是一种取代的哌啶衍生物,在有机合成中被广泛用作形成肽和拟肽分子的连接体,被广泛应用于肽合成和肽模拟,也用于合成药物、生物聚合物和其他有机分子。 | |||
T125100 |
Pteroside B
|
Others | Others |
Pteroside B 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125100。 | |||
T131269 |
Compound N039-0033
|
Others | Others |
Compound N039-0033 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131269。 | |||
T131226 |
Compound N058-0062
|
Others | Others |
Compound N058-0062 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131226。 | |||
T131284 |
Compound N038-0008
|
Others | Others |
Compound N038-0008 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131284。 | |||
T131363 |
Compound N011-0459
|
Others | Others |
Compound N011-0459 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131363。 | |||
T131633 |
Compound 1554-0035
|
Others | Others |
Compound 1554-0035 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131633。 | |||
T4675 |
4-Carboxyisothiazole
|
Others | Others |
4-Carboxyisothiazole 用作中间体。 | |||
T7038 |
4-Methylayapin
4-甲基-6,7-亚甲基二氧代香豆素,4-METHYL-6,7-METHYLENEDIOXYCOUMARIN |
Others | Others |
4-Methylayapin 用作中间体。 | |||
T3222 |
16,17-Epoxypregnenol
16alpha,17alpha-Epoxypregnenolone,16,17-环氧孕烯醇酮 |
Others | Others |
16,17-Epoxypregnenol 用作药物中间体。 | |||
T131283 |
Compound N038-0206
|
Others | Others |
Compound N038-0206 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131283。 | |||
T131323 |
Compound N017-0016
|
Others | Others |
Compound N017-0016 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131323。 | |||
T131321 |
Compound N017-0020
|
Others | Others |
Compound N017-0020 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131321。 | |||
T131278 |
Compound N039-0003
|
Others | Others |
Compound N039-0003 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131278。 | |||
T131296 |
Compound N034-0003
|
Others | Others |
Compound N034-0003 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131296。 | |||
T131276 |
Compound N039-0006
|
Others | Others |
Compound N039-0006 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131276。 | |||
T9404 |
2,5-DIBROMO-3,4-DINITROTHIOPHENE
|
Others | Others |
2,5-DIBROMO-3,4-DINITROTHIOPHENE 又称2,5-DBT,是一种有机溴化合物,在生物学研究、化学合成的中具有广泛应用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4766 |
3-Methylglutaric acid
|
Endogenous Metabolite | Metabolism |
3-Methylglutaric acid 是亮氨酸代谢物,是一种与两种亮氨酸途径 HMGCL、AUH 酶缺陷显著相关的 C6 二元羧酸有机酸。 | |||
T9502 |
2-Tridecanone
|
Others | Others |
2-Tridecanone 是一种非生物碱杀虫剂,分离自野生番茄 Lycopersicon hirsutum f. glabratum,具有挥发性。 | |||
T11849 |
Lignin
木质素,脱碱的,木质素,Lignine |
Others | Others |
Lignin (Lignine) 是一种具有生物可降解性和生物相容性的天然复合生物聚合物。它是植物细胞壁的主要成分,是一种可再生的芳香族聚合物,具有显著的抗氧化作用。 | |||
T1045 |
Trimipramine maleate
Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐 |
Dopamine Receptor; 5-HT Receptor; Antibacterial; Adrenergic Receptor; Norepinephrine; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Trimipramine maleate (Surmontil maleate) 是一种 5-HT 受体拮抗剂,对 5-HT1C、5-HT2和 5-HT1A 受体的 pKi 值分别为 6.39、8.10和 4.66。 | |||
T19866 |
Indican
NSC-87517,3-Indoxyl-beta-D-glucopyranoside,3-吲哚基-beta-D-吡喃葡萄糖苷,NSC 87517,NSC87517,Indoxyl-β-D-glucoside |
OAT; MRP | Immunology/Inflammation; Membrane transporter/Ion channel |
Indican (Indoxyl-β-D-glucoside) 是吲哚酚的一种糖苷,染料靛蓝和靛玉红的前体。它的主要代谢物是硫酸吲哚酚 (IS)。其中 IS 是尿毒症毒素,是有机阴离子转运蛋白1 (OAT 1)、OAT 3 和多药耐药相关蛋白4 (MRP 4) 的底物/抑制剂。 | |||
T8379 |
Aconitic Acid
|
Others | Others |
Aconitic acid 是一种有机酸。 | |||
T4729 |
Phosphonoacetic acid
|
Endogenous Metabolite | Metabolism |
Phosphonoacetic acid 是内源性代谢产物的一种。 | |||
T5232 |
3-Methyl-2-oxobutanoic acid
3-甲基-2-氧丁酸,2-Oxoisovaleric acid,alpha-Ketoisovaleric acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) 是大肠杆菌中泛酸的前体。它是由支链氨基酸的不完全分解产生的一种异常代谢物。 | |||
T1373 |
AC-Beta-ALA-OH
|
Amino Acids and Derivatives | Metabolism |
AC-Beta-ALA-OH 是单 N-保护氨基酸 (MPAA) 配体,也是异常氨基酸代谢物。 | |||
T8192 |
Pentacosanoic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
Pentacosanoic acid 是戊酸的共轭酸,是 25 碳长链饱和脂肪酸。 | |||
T8091 |
trans-4-Hydroxycyclohexanecarboxylic Acid
|
Others | Others |
trans-4-Hydroxycyclohexanecarboxylic acid 是一种合成环己烷酸的底物 (substrate)。它是肠道细菌代谢的副产物 (by-product),能够通过尿路排泄。 | |||
T8254 |
Chrysoobtusin
|
Others | Others |
Chrysoobtusin 是一种蒽醌衍生物,分离自决明子。其中决明子具有保肝、通便、明目的作用。 | |||
T3O2709 |
Bronze Red
808猩红,Scarlet 808 |
Others | Others |
Bronze Red 属于酰胺类有机物,可用于含量测定、鉴定、药理实验等。 | |||
T1334 |
Hydroquinidine
奎宁树,氢化奎宁定,Hydroconchinine,Dihydroquinidine,Hydroconquinine,(+)-Hydroquinidine,Dihydroquinine |
Potassium Channel; Sodium Channel | Membrane transporter/Ion channel |
Hydroquinidine ((+)-Hydroquinidine) 是 Quinidine(一种抗心律不齐药) 的衍生物。它能够延长 QT 间隔,表现出抗心律不齐活性。 | |||
T19382 |
Isoguanine
2-羟基-6-氨基嘌呤,异鸟嘌呤 |
Nucleoside Antimetabolite/Analog | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Isoguanine 是一种嘌呤碱基,是鸟嘌呤的异构体,可作为有机合成的砌块。 | |||
T7571 |
1-Methyladenosine
|
Endogenous Metabolite | Metabolism |
1-Methyladenosine 是 RNA 修饰,主要来自两种不同的反应类型,酶催化反应以及 RNA 与某些烷化剂反应。 | |||
TQ0234 |
Epoxymicheliolide
1β,10β-Epoxymicheliolide,环氧木香内酯 |
Others | Others |
Epoxymicheliolide 是木香内酯衍生物的一种,抑制破骨细胞生成。 | |||
T4778 |
3-Hydroxybenzaldehyde
|
Others; Dehydrogenase | Metabolism; Others |
3-Hydroxybenzaldehyde 是很多酚类化合物的前体分子。它是人和大鼠醛脱氢酶 (ALDH) 的底物 (substrate)。它具有血管保护的作用。 | |||
T8010 |
Dibutyl sebacate
Dibutyl decanedioate,癸二酸二丁酯 |
Others | Others |
Dibutyl sebacate (Dibutyl decanedioate) 是一种常作为塑料生产中的增塑剂的癸二酸二丁酯。 | |||
T3159 |
Guaiazulene
愈创奥,azulon,Vetivazulen,愈疮奥,Eucazulen |
Others; Endogenous Metabolite | Metabolism; Others |
Guaiazulene (azulon) 存在于几种药用植物和芳香植物精油中,具有抗氧化特性,对神经元和 N2a-NB 细胞有体外细胞毒特性。 | |||
T5298 |
4-hydroxy-3-methylbenzoic acid
4-羟基-3-甲基苯甲酸,4,3-Cresotic acid |
Others; Endogenous Metabolite | Metabolism; Others |
4-hydroxy-3-methylbenzoic acid (4,3-Cresotic acid) 是一种来自健康人群的尿样中鉴定的正常有机酸。 | |||
T2769 |
3-Aminopropionitrile fumarate (2:1)
Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,3-氨基丙腈,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate |
Others | Others |
3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) 是一种能抑制胶原蛋白(collagen)交联的山黧豆素。 | |||
T8050 |
2-Methyltetrahydrofuran-3-one
|
Others | Others |
2-Methyltetrahydrofuran-3-one 是一种烤咖啡的挥发性成分。 | |||
T8693 |
Diallyl Trisulfide
二烯丙基三硫化物,二烯丙基三硫醚 |
Apoptosis; Reactive Oxygen Species; Antifungal | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Diallyl Trisulfide 是一种在大蒜中发现的有机多硫化物,可作为 H2S 供体。它抑制扩张性青霉的生长,有抗癌能力。 | |||
T4773 |
3-Ethoxy-3-oxopropanoic acid
Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯 |
Others; Endogenous Metabolite | Metabolism; Others |
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) 是内源性代谢产物的一种。 | |||
TN6740 |
Emodinanthrone
大黄素蒽酮,Emodin anthranol,Emodin anthrone,emodinol |
Others; Antibiotic | Microbiology/Virology; Others |
Emodinanthrone 是一种蒽醌类化合物,是大黄素的前体,具有抗生素活性。它抑制大肠杆菌膜囊泡中呼吸驱动的溶质转运。 | |||
T5272 |
3-(3-Methoxyphenyl)propionic acid
3-(3-甲氧基苯基)丙酸,3-Methoxyhydrocinnamic acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-(3-Methoxyphenyl)propionic acid (3-Methoxyhydrocinnamic acid) 是人体自然代谢的有机酸,排泄于尿液中。 | |||
T8034 |
Dimethyl Trisulfide
|
Others; Endogenous Metabolite | Metabolism; Others |
Dimethyl trisulfide 是存在于大蒜,洋葱,西兰花和类似植物中的有机三硫化物。它是一种氰化物解毒剂。 | |||
TN2362 |
Sudan I
苏丹红Ⅰ,苏丹红一号,Solvent Yellow 14 |
Others; Antibacterial | Microbiology/Virology; Others |
Sudan I (Solvent Yellow 14) 是一种偶氮共轭红色染料,抑制产气荚膜梭菌和鼠李糖菌的生长,可用于一些产品的添加剂,如油、溶剂或抛光剂。 | |||
T40607 |
2,4,6-Trimethylphenol
Mesitol |
Others | Others |
2,4,6-Trimethylphenol (Mesitol) 是一种与有机物 (3DOM*) 反应的探针化合物,可在水溶液中被单线态氧快速氧化。 | |||
T7126 |
Hydroquinine
氢化奎宁,dihydroquinine |
Others | Others |
Hydroquinine 是金鸡纳生物碱,可用于制备衍生物(如 C9 脱氢喹啉、9-乙酰氧基-10,11-二氢喹、 10,11-二氢喹单盐酸盐等)。 | |||
T8163 |
Glucovanillin
葡萄糖香草醛,Vanillin 4-O-β-D-Glucoside,4-(β-D-葡萄糖氧基)-3-甲氧基苯甲醛 |
Others | Others |
Glucovanillin (Vanillin 4-O-β-D-Glucoside) 是提取于青荚中,通过细胞壁降解和葡萄糖酐水解的酶联合作用可转化为香草醛。 | |||
T5277 |
3-Furanoic acid
3-Furoic acid,3-糠酸,3-Carboxyfuran,3-Furancarboxylic acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-Furanoic acid (3-Carboxyfuran) 是内源性代谢产物的一种。 | |||
T2911 |
Stevioside
甜菊苷,蛇菊苷 |
TLR | Immunology/Inflammation |
Stevioside 是一种天然甜味剂,从甜叶菊叶中提取的获得,具有抗癌作用。 | |||
T5650 |
2,2':5',2''-Terthiophene
alpha-三联噻吩,α-Terthienyl,Trithiophene |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
2,2':5',2''-Terthiophene (Trithiophene) 是杂环噻吩的低聚物,可用作有机合成的砌块 。 | |||
T13854 |
Quininic acid
|
NMDAR | Neuroscience |
Quininic acid 是从蓝桉、金鸡纳树皮和其他紫菀科植物中提取出来的有机酸,可被当作一种 NMDA 受体激动剂.。 | |||
T5261 |
(E)-Oct-2-enoic acid
trans-2-Octenoic acid,2-Octenoate,2-辛烯酸,2-Octenoic acid |
Others; Endogenous Metabolite | Metabolism; Others |
(E)-Oct-2-enoic acid (2-Octenoate) 是内源性代谢产物的一种。 | |||
T1717 |
alpha-Mangostin
α-倒捻子素,α-Mangostin,Mangostin |
Apoptosis; Virus Protease; Dehydrogenase; Reactive Oxygen Species; Antibacterial; Antifungal | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
alpha-Mangostin (Mangostin) 是有多种生物活性的膳食呫吨酮。它是一种IDH1突变体的抑制剂,Ki 值为 2.85 μM。 | |||
T5542 |
Tiglic acid
惕格酸,Sabadillic acid,Tiglinic acid,巴豆酸,Cevadic acid |
Endogenous Metabolite; HSV | Metabolism; Microbiology/Virology |
Tiglic acid 是一种存在于巴豆油和其他几种天然产物中的单羧酸不饱和有机酸。它具有植物代谢物的作用。 | |||
T9780 |
3,4, 5-trimethoxyphenylacetic acid
|
Endogenous Metabolite | Metabolism |
3,4, 5-trimethoxyphenylacetic acid 是有机合成中常见的中间体,其主要用途是将其羧基转化为相应的用途。 | |||
T0022 |
Taurine
牛磺酸,2-Aminoethanesulfonic acid |
LDL; Endogenous Metabolite; Autophagy | Autophagy; Metabolism |
Taurine (2-Aminoethanesulfonic acid) 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。 | |||
T4854 |
Acetoacetic acid lithium salt
LithoTab acetoacetate,Lithium acetoacetate,Lithium 3-Oxobutyrate,乙酰乙酸锂 |
Others; Endogenous Metabolite | Metabolism; Others |
Acetoacetic acid lithium salt (Lithium 3-Oxobutyrate) 是内源性代谢产物的一种。 | |||
T4842 |
1H-pyrazole
1,2-Diazole,Pyrazole,吡唑 |
Others; Endogenous Metabolite | Metabolism; Others |
1H-pyrazole (1,2-Diazole) 是内源性代谢产物的一种。 | |||
T2893 |
Muscone
3-Methylcyclopentadecanone,Methylexaltone,麝香酮 |
MMP; TNF; NF-κB; NOD-like Receptor (NLR); P-gp; Interleukin | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB; Proteases/Proteasome |
Muscone (3-Methylcyclopentadecanone) 是中药麝香的一种主要活性单体。它抑制NF-κB 和NLRP3炎性小体的活化,显著降低炎性细胞因子水平,并最终改善心脏功能和存活率。 | |||
T5658 |
Adamantane
|
Others | Others |
Adamantane 是许多化合物的结构骨架,也是有机多面体化合物的物理化学和生物学特性,在制药工业中有实际应用。 | |||
T0415 |
Guanidine hydrochloride
Guanidine HCl,Aminoformamidine HCl,盐酸胍,Aminoformamidine Hydrochloride,Guanidinium chloride |
Others; Arginase; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Others |
Guanidine hydrochloride (Aminoformamidine Hydrochloride) 是一种强离液剂和一种蛋白质的强变性剂。 | |||
T7921 |
β-Cyclocitral
beta-Cyclocitral,β-环柠檬醛 |
Others | Others |
β-Cyclocitral 是 β-胡萝卜素的挥发性氧化衍生物,是微囊藻特有的掠食性动物防御信号。它是一种强大的驱虫剂。它是主要的挥发性萜类化合物之一,可以上调防御基因的表达,从而增强过量光照 (EL) 的适应性。 | |||
T5723 |
Menthol
薄荷脑,DL-Menthol |
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
Menthol (DL-Menthol) 是从薄荷或薄荷油中得到的一种天然产物,具有调味和局部麻醉特性。它通过抑制神经元细胞膜的 Ca++电流,刺激冷感受器,从而产生清凉的感觉。 | |||
T8032 |
4-Pentenoic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
4-Pentenoic acid 是内源性代谢产物的一种。 | |||
T3328 |
Angelic Acid
2-Methylisocrotonic acid,(Z)-2-Methylbut-2-enoic acid,当归酸,cis-2-Methyl-2-butenoic acid |
Others | Others |
Angelic Acid ((Z)-2-Methylbut-2-enoic acid) 是一种存在于Anthemis nobilis 精油中的酯,能够促进伤口愈合,具有促进安定和精神药物的作用。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02125 |
SLCO2B1 Protein, Human, Recombinant (His & Myc)
Solute carrier family 21 member 9,Solute carrier organic... |
Human | E. coli |
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. | |||
TMPH-01296 |
GPX5 Protein, Human, Recombinant (GST & His)
GPX5,Glutathione peroxidase 5,Epididymal secretory glutathio... |
Human | E. coli |
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | |||
TMPH-01645 |
MGP Protein, Human, Recombinant (His)
MGP,Cell growth-inhibiting gene 36 protein,Matrix Gla protei... |
Human | E. coli |
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. MGP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.5 kDa and the accession number is P08493. | |||
TMPH-03054 |
Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)
|
Neosartorya fumigata | E. coli |
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Required for virulence. | |||
TMPH-03483 |
Saxiphilin Protein, Aquarana catesbeiana, Recombinant (His)
Saxiphilin |
Lithobates catesbeiana | HEK293 Cells |
Binds specifically to the neurotoxin saxitoxin. Its physiological role may be to transport or sequester an endogenous organic molecule other than Fe(3+). It may participate in a detoxification mechanism for neutralizing a microbial toxin. Saxiphilin Protein, Aquarana catesbeiana, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis-Myc tag. The predicted molecular weight is 43.7 kDa and the accession number is P31226. | |||
TMPH-00072 |
2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)
Thioredoxin-dependent peroxiredoxin BAS1,2-Cys peroxiredoxin... |
Arabidopsis thaliana | P. pastoris (Yeast) |
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf. 2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96291. | |||
TMPH-02199 |
TXNRD2 Protein, Human, Recombinant (His)
Thioredoxin-dependent peroxide reductase, mitochondrial,Pero... |
Human | E. coli |
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. TXNRD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.5 kDa and the accession number is P30048. | |||
TMPY-01900 |
Kallikrein 4/KLK4 Protein, Human, Recombinant (His)
PSTS,kallikrein,kallikrein-related peptidase 4,EMSP,EMSP1,AR... |
Human | HEK293 Cells |
Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. Kallikrein-4 / KLK4 is a serine protease expressed during enamel maturation, and proteolytic processing of the enamel matrix by KLK4 is critical for proper enamel formation. Kallikrein-4 / KLK4 contains one peptidase S1 domain. Kallikrein-4 / KLK4 is secreted by transi... | |||
TMPH-03108 |
GPX5 Protein, Pig, Recombinant (E. coli, His & Myc)
GPX5,Glutathione peroxidase 5,Epididymis-specific glutathion... |
Sus scrofa (Pig) | E. coli |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX... | |||
TMPH-03109 |
GPX5 Protein, Pig, Recombinant (His & Myc)
GPX5,Epididymis-specific glutathione peroxidase-like protein... |
Sus scrofa (Pig) | P. pastoris (Yeast) |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX... | |||
TMPJ-00442 |
Otolin-1 Protein, Human, Recombinant (His)
Otolin-1,otolin 1,C1qTNF15,OTOL1 |
Human | HEK293 Cells |
Otolin (OTOL1), also known as C1qTNF15, is an approximately 65 kDa protein found in the otoconial membrane lining the cochlea and vestibular labyrinth of the inner ear. Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear. It associates into multimers and disulfide-linked oligomers and also associates with other otoconial proteins including and Otoconin-90 (also known as... | |||
TMPJ-00666 |
CLIC2 Protein, Human, Recombinant (His)
CLIC2,XAP121,Chloride Intracellular Channel Protein 2 |
Human | E. coli |
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be d... | |||
TMPY-03857 |
MMGT1 Protein, Human, Recombinant (His)
membrane magnesium transporter 1,TMEM32,EMC5 |
Human | HEK293 Cells |
MMGT1 (Membrane Magnesium Transporter 1, also known as EMC5 and TMEM32) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein belongs to the membrane magnesium transporter (TC 1.A.67) family which is a group of magnesium transporters that are part of the TOG superfamily. It mediates Mg(2+) transport. MMGT1 is described as having 335 amino acids and five TMSs with an N-terminal cleavage site and some phosphorylation sites. It is widely expressed ... | |||
TMPJ-00728 |
Beta-galactosidase Protein, E. coli, Recombinant
Beta-gal,Beta-galactosidase,lacZ,β-galactosidase Protein,β-g... |
E. coli | E. coli |
β-galactosidase is an exoglycosidase which hydrolyzes the β-glycosidic bond formed between a galactose and its organic moiety. It may also cleave fucosides and arabinosides but with much lower efficiency. β-galactosides include carbohydrates containing galactose where the glycosidic bond lies above the galactose molecule. Substrates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins. It is an essential enzyme in the human body. Deficienci... | |||
TMPH-03753 |
MYLK Protein, Human, Recombinant (His)
MYLK,Myosin light chain kinase, smooth muscle,Telokin,Kinase... |
Human | E. coli |
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMID-0026 |
Acetophenone-d8
|
||
Acetophenone-d8 是 Acetophenone 的氘代化合物。Acetophenone 的 CAS 号为 98-86-2。Acetophenone 是一种有机化合物,能够用作香料。 | |||
TNU1192 |
N1-Methyl-d3-pseudouridine
|
||
N1-Methyl-d3-pseudouridine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 TNU1192。 | |||
T64769 |
Propan-d7-2-amine hydrochloride
|
||
Propan-d7-2-amine hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64769。 | |||
T64570 |
Succinic acid-d6
|
||
Succinic acid-d6 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64570。 | |||
T64761 |
5-(Methyl-d3)-dibenzothiophenium, 1,1,1-trifluoromethanesulfonate
|
||
5-(Methyl-d3)-dibenzothiophenium, 1,1,1-trifluoromethanesulfonate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64761。 | |||
T64482 |
Urea-13C
|
||
Urea-13C 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64482,CAS号为 58069-82-2。 | |||
T65313 |
Methy-d
|
||
Methy-d 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65313,CAS号为 7575-93-1。 | |||
T65001 |
Benzoicacid-d5
|
||
Benzoicacid-d5 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65001,CAS号为 1079-02-3。 | |||
TMIJ-0479 |
Dicamba-d3 (methoxy-d3)
|
||
Dicamba-d3 (methoxy-d3) 是 Dicamba 的氘代化合物。Dicamba 的 CAS 号为 1918-00-9。Dicamba 是一种氯化有机除草剂。 Dicamba 可用于防治阔叶杂草。 | |||
TMID-0161 |
5-alpha-Cholestane-2,2,4,4-d4
|
||
5-alpha-Cholestane-2,2,4,4-d4 是 5-alpha-Cholestane 的氘代化合物。5-alpha-Cholestane 的 CAS 号为 481-21-0。5α-Cholestane 属于一类称为胆甾烷类固醇的有机化合物。 | |||
TMID-0169 |
Taurine-d4
|
||
Taurine-d4 是 Taurine 的氘代化合物。Taurine 的 CAS 号为 107-35-7。Taurine 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。 | |||
TMIJ-0469 |
Metolachlor-d6 (propyl-d6)
|
||
Metolachlor-d6 (propyl-d6) 是 Metolachlor 的氘代化合物。Metolachlor 的 CAS 号为 51218-45-2。Metolachlor 是出苗前的选择性的,氯乙酰苯胺除草剂,由四种立体异构体组成的手性除草剂。它可用于控制玉米和其他农作物中的各种一年生草和阔叶杂草。 | |||
TMID-0250 |
2-hydroxy-4-methoxybenzophenone-d5
|
||
2-hydroxy-4-methoxybenzophenone-d5 是 2-hydroxy-4-methoxybenzophenone 的氘代化合物。2-hydroxy-4-methoxybenzophenone 的 CAS 号为 131-57-7。Oxybenzone 是晒黑和皮肤保护剂中常用的紫外线过滤剂。它是二苯甲酮的衍生物,用作破坏内分泌的化学物质,可穿透胎盘和血脑屏障。它损害自噬,改变表观遗传状态并破坏凋亡神经元细胞中的类维生素 X 受体信号传导。 | |||
TMID-0257 |
Quinoline-d7
|
||
Quinoline-d7 是 Quinoline 的氘代化合物。Quinoline 的 CAS 号为 91-22-5。Quinoline 存在于酒精饮料中。 它是一种来自包括薄荷在内的多种植物的生物碱。 也存在于可可、红茶和苏格兰威士忌中。 老化的样品,如果暴露在光线下,会变成黄色,然后变成棕色。 | |||
T70313 |
Indoxyl Sulfate-d5 potassium salt
|
||
Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). ... | |||
TMID-0167 |
6-Hydroxypurine-d4
|
||
6-Hydroxypurine-d4 是 6-Hydroxypurine 的氘代化合物。6-Hydroxypurine 的 CAS 号为 68-94-0。Hypoxanthine,也被称为 purine-6-ol 或 Hyp,属于嘌呤类有机化合物。Hypoxanthine 是一种天然存在的嘌呤衍生物,是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下,Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤,黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。 | |||
TMIJ-0047 |
Isobutyric-d6 acid
|
||
Isobutyric-d6 acid 是 Isobutyric acid 的氘代化合物。Isobutyric acid 的 CAS 号为 79-31-2。Isobutyric acid 是一种羧酸或短链脂肪酸,具有特征性的汗味。通过微生物(肠道)代谢产生少量异丁酸。在某些食物或发酵饮料中也可能发现少量。 | |||
TMIJ-0053 |
2-Methylpropionic-d7 acid
|
||
2-Methylpropionic-d7 acid 是 2-Methylpropionic acid 的氘代化合物。2-Methylpropionic acid 的 CAS 号为 79-31-2。Isobutyric acid 是一种羧酸或短链脂肪酸,具有特征性的汗味。通过微生物(肠道)代谢产生少量异丁酸。在某些食物或发酵饮料中也可能发现少量。 | |||
TMIJ-0052 |
Propionicacid-d5
|
||
Propionicacid-d5 是 Propionicacid 的氘代化合物。Propionicacid 的 CAS 号为 79-09-4。Propionic acid 被广泛用作食品中的抗真菌剂。它以低水平天然存在于乳制品中,并与其他短链脂肪酸 (SCFA) 一起普遍存在于人类和其他哺乳动物的胃肠道中,作为微生物消化碳水化合物的最终产物。在动物体内有显着的生理活性。 | |||
TMIJ-0054 |
Propionic-2,2-d2 acid
|
||
Propionic-2,2-d2 acid 是 Propionic acid 的氘代化合物。Propionic acid 的 CAS 号为 79-09-4。Propionic acid 被广泛用作食品中的抗真菌剂。它以低水平天然存在于乳制品中,并与其他短链脂肪酸 (SCFA) 一起普遍存在于人类和其他哺乳动物的胃肠道中,作为微生物消化碳水化合物的最终产物。在动物体内有显着的生理活性。 |