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Targets Recommended: Others

47

抑制剂 & 化合物

27

天然产物

1

化合物库

17

重组蛋白

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Cat. No. Product Name
L2196 抗卵巢癌化合物库

1867 compounds
1867 种与卵巢癌相关的化合物,可以用于抗卵巢癌药物研发和药理研究

化合物库

抗卵巢癌化合物库
Cat.No: L2196
Compounds: 1867
Cat. No. Product Name Target Signaling Pathways
T0023 Valethamate bromide

Ediposin,Epidozin,戊沙溴铵,Epidosin,Resitan

Others Others
Valethamate bromide (Resitan) 是快速作用的抗胆碱能解痉和肌萎缩剂,是一种酯,能够改善宫颈扩张加速分娩。
T12579 RAMB4

PTP1B-IN-9

Proteasome Proteases/Proteasome; Ubiquitination
RAMB4 (PTP1B-IN-9) 是一种泛素-蛋白酶体系统(UPS)应激源,是通过抑制 20S 蛋白酶体催化活性物质上游泛素介导的蛋白质降解而产生。它能够在不影响 20S 蛋白酶体催化活性的情况下触发泛素蛋白酶体系统 (UPS) 应激反应。
T20029 Buformin hydrochloride

NSC528218,NSC-528218,盐酸丁双胍,NSC 528218

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Buformin hydrochloride (NSC-528218) 是一种有效的 AMPK 激活剂,是一种双胍类的口服抗糖尿病药物。Buformin 延缓胃肠道对葡萄糖的吸收,增加胰岛素敏感性和葡萄糖对细胞的吸收,并抑制肝脏对葡萄糖的合成。Buformin 也具有抗癌活性,可用于各种癌症研究。
T22450 Tyrphostin B44, (+) enantiomer

酪氨酸磷酸化抑制剂AG 835

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tyrphostin B44, (+) enantiomer 是一种表皮生长因子受体 (EGFR) 激酶抑制剂,IC50 为 0.86 μM,活性低于 (-) 对映体。
T23867 Cdc7-IN-7c

Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c

CDK Cell Cycle/Checkpoint
Cdc7-IN-7c (Cdc7 inhibitor-7c) 具有抗肿瘤活性,对肝癌,肺癌,肾癌,脑癌,宫颈癌有抑制作用。
T27612 INI-43

INI 43,INI43

Others Others
INI-43 是Nuclear Import-43 的抑制剂,通过靶向 Kpnβ1 对各种宫颈和食管癌细胞系显示出显着的细胞毒性作用,并干扰 Kpnβ1 和已知的 Kpnβ1 cargo 蛋白、NFAT、NFκB、AP-1和NFY 的核定位。
TP1554L HPV16 E7 (86-93) acetate

HPV16 E7 (86-93) acetate(160212-93-1 Free base)

Others Others
HPV16 E7 (86-93) acetate 是人源白细胞抗原 A2.1 限制性 HPV16 E7 的衍生肽,在宫颈癌中具有免疫原性。
T12042 Minnelide

Apoptosis; Virus Protease Apoptosis; Microbiology/Virology
Minnelide 是水溶性雷公藤内酯前药,具有抗癌症抗肿瘤活性,可诱导细胞凋亡,可预防足细胞损伤。Minnelide 通过阻断 HPV 诱导的 p53 和 pRb 变化来抑制宫颈癌的生长。
T6858 Hydroxyprogesterone caproate

Primolut Depot,Delalutin,Hormofort,己酸孕酮,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate

Autophagy Autophagy
Hydroxyprogesterone caproate (Delalutin) 是一种甾体,是一种人工合成的孕激素。
T20742 TG-89

FLT; c-RET; JAK Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
TG-89是 JAK2、JAK3、RET 和 FLT3的抑制剂,对 JAK2的 IC50值为11.2 μM,在卵巢癌和宫颈癌的治疗中显示出抗癌活性。
TP1283L VIP(6-28)(human, rat, porcine, bovine) acetate

Others Others
VIP(6-28)(human, rat, porcine, bovine) acetate 是外源性血管活性肠肽 (VIP) 受体对颈上神经节 (SCG) 中 cAMP 作用的拮抗剂。
T67786 ABI-1968 PM

Others Others
ABI-1968 PM 是ABI-1968的一种衍生物。ABI-1968是一种细胞凋亡刺激剂,是一种病毒复制抑制剂。ABI-1968可用于研究宫颈上皮内瘤样病变、乳头状瘤病毒感染和鳞状上皮内病变。
T9939 JMJD6 inhibitor WL12

2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-,ZINC6733033

Others Others
JMJD6 inhibitor WL12 (ZINC6733033) 是一种JMJD6 抑制剂,能够抑制JMJD6依赖的癌细胞增殖,包括宫颈癌细胞和肝癌细胞,为研究JMJD6在癌症发展中的生物学功能提供了一个小分子探针。
T60485 DIF-3

Others Others
DIF-3 is a chemical compound that acts by activating GSK-3β to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in DLD-1 cells. This compound exerts a potent antiproliferative effect on the HeLa human cervical cancer cell line by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression [1].
T17228 Sabizabulin

ABI-231,VERU-111

Microtubule Associated Cytoskeletal Signaling
Sabizabulin (ABI-231) 是一种有效且具有口服生物利用度的 α 和 β 微管蛋白抑制剂,可对抗黑色素瘤和前列腺癌细胞系。 Sabizabulin 通过靶向 HPV E6 和 E7 抑制宫颈癌细胞的肿瘤生长和转移表型。 Sabizabulin 显示出抗增殖活性,可用于前列腺癌研究。
T16773 Ro 90-7501

RO-90-7501

Apoptosis; Phosphatase; ATM/ATR; Gamma-secretase Apoptosis; DNA Damage/DNA Repair; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
Ro 90-7501 是一种淀粉样 β42 (Aβ42) 原纤维和 TPR 依赖性 PP5 抑制剂,是一种新型宫颈癌细胞放射增敏剂,可抑制 ATM 磷酸化 ,促进细胞凋亡,诱导细胞周期停滞。Ro 90-7501 具有抗病毒活性和潜在的抗癌活性,抑制 ATM 磷酸化和 DNA 修复,抑制HCMV。
T23888 CID-5056270

ROCK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
CID-5056270具有抗癌活性,对肺癌肛门癌、膀胱癌、宫颈癌、外阴癌、阴茎癌、伯基特淋巴瘤乳腺癌和骨癌具有抑制作用,可用来研究高血压、老年痴呆症度、阿尔茨海默病和动脉硬化。
T2597 Norgestrel

甲基炔诺酮,SH-850,FH 122-A,炔诺孕酮,WY-3707,SH-70850

Estrogen/progestogen Receptor; Reactive Oxygen Species Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
Norgestrel (WY-3707) 是一种孕酮的合成类似物,是一种口服避孕药中常见的化合物,也是一种神经保护性强抗氧化剂,能够防止光诱导的感光细胞中的ROS 的生成以及细胞死亡。
T77423 Lirilumab

ONO-4483,IPH2102

Virus Protease Microbiology/Virology
Lirilumab (IPH2102) 是一种针对杀伤性免疫球蛋白样受体抗体 KIR2D 的抗体,具有抗肿瘤活性,通过 Vav1 依赖性 NF-κB 去抑制增强自然杀伤细胞的抗 HPV+ 宫颈癌活性,可用于研究白血病、头颈部鳞状细胞癌 (SCCHN)。
T76863 Elezanumab

AE12-1Y-QL,ABT-555

TGF-beta/Smad Stem Cells
Elezanumab(ABT-555) 是一种有效的人抗 RGMa 单克隆抗体。Elezanumab 通过 SMAD1/5/8 通路发挥对 RGMa 介导的 BMP 信号传导的抑制作用,IC50 约为 97 pM。在神经元损伤和脱髓鞘模型中,Elezanumab 促进神经再生、神经保护和神经恢复。Elezanumab 促进皮质脊髓轴突生长为脊髓灰质,并增强腹角的血清素能神经支配,形成颈部病变尾部的突触连接。
T34508 Sanazole

AK2123,AK-2123,AK 2123

Others Others
Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.
T26601 ALRT 1550

LG-1550,LGD-1550,ALRT-1550,LG1550,ALRT-550,ALRT1550

Others Others
ALRT 1550, a retinoic acid agent (RAR) agonist, is used potentially for the treatment of cervical carcinoma.
T29202 Zalypsis

PM00104,PM 10450,PM-00104,PM 00104,PM10450,PM-10450

Others Others
Zalypsis, a transcription factor inhibitor, is used potentially for the treatment of lymphoma, and cervical carcinoma.
T70594 Gliotoxin monoacetate

Others Others
Gliotoxin monoacetate is a toxin found in Aspergillus. It induces apoptosis in cervical cancer cells and chondrosarcoma cells, suppresses the adaptive immune response in leukocytes, and inhibits the proteasome in Plasmodium falciparum.
T76015 HPV16 E7 (86-93) (TFA)

HPV16 E7 (86-93) TFA,一种HLA-A2.1限制的HPV16 E7衍生肽,在宫颈癌中显示出免疫原性。
T76716 Cadonilimab

Cadonilimab (AK104) 为一种IgG1支架Fc工程化的人源化抗体,针对PD1/CTLA4。适用于转移性宫颈癌研究。
T25912 Oxypyrronium bromide

L.D. 3055,Immetropan,LD 3055,LD3055,LD-3055

Others Others
Oxypyrronium bromide 一种含有季铵的抗胆碱能和解痉剂。在动物模型中,它抑制胃运动、迷走神经刺激或乙酰胆碱静脉注射引起的低血压;鼓索神经刺激引起的流涎和节前颈交感神经刺激引起收缩。
T81732 Myosin light chain kinase fragment 11-19 amide

MLCK(11-19) amide

Myosinlight chain kinase fragment 11-19 amide (MLCK(11-19) amide) 为MLCK专一性多肽抑制剂,具抑制低渗透压刺激下Ca2+入细胞的能力,并可应用于人类宫颈癌研究。
T60544 HPV18-IN-1

Others Others
HPV18-IN-1 (Compound H1) 是有效的HPV18抑制剂,可防止宫颈癌细胞的过早和异常细胞增殖。它可抑制 E7-Rb-E2F 细胞通路和 DNA 甲基化, 具有癌症研究的潜力。
T76709 Zimberelimab

Zimberelimab 是一种全人源IgG4抗PD-1单克隆抗体,具有很高的亲和力和选择性。 Zimberelimab 具有抗肿瘤活性,可用于各种癌症研究,包括宫颈癌、非小细胞肺癌和霍奇金淋巴瘤。
T60933 B-Raf IN 7

Others Others
B-Raf IN 7 (compound 6a) 是 B-Raf 的有效抑制剂,IC50值为 110.23 nM。B-Raf IN 7 对结肠癌细胞(HCT-116)、乳腺癌细胞 (MCF-7)、肝癌细胞 (HEPG-2)、人宫颈癌细胞 (Hela) 和人前列腺癌细胞 (PC-3) 具有抗肿瘤活性。其 IC50值分别为 7.50、9.87、10.57、11.63 和 12.83 μM。
T81400 Pritumumab

Pritumumab是一种自然源的人类IgG1kappa单克隆抗体,其最初源于一位宫颈癌患者的区域淋巴结分离得到。该单抗特异性地识别波形蛋白,该蛋白在多种恶性肿瘤细胞表面展现。Pritumumab在胶质母细胞瘤的科研应用中具有潜在价值。
T68667 Oxanosine

Others Others
Oxanosine is an analog of guanosine that has been found in S. capreolus and has diverse biological activities, including antibacterial, antiviral, and anticancer properties. It is active against a variety of bacteria, including S. flexneri, P. mirabilis, and E. coli (MICs = 6.25, 12.5, 25 µg/ml, respectively, on peptone, but not nutrient, agar). Oxanosine inhibits replication of the HIV-1 strain IIIb in infected CEM and U937, but not H9, cells (EC50s = 7, 27, and >500 µg/ml, respectively). It al...
T83741 S7 TFA

Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH

S7是一种IL-6受体的肽类拮抗剂,能够浓度依赖性地抑制IL-6与IL-6受体的结合。在C-33 A宫颈癌细胞和RPMI-8226 B细胞淋巴细胞中,S7 (50 µM) 能抑制IL-6诱导的VEGF水平增加。在每两天给药一次,剂量为50 mg/kg的条件下,S7能减少IL-6过表达的C-33 A宫颈癌小鼠异种移植模型中的肿瘤体积。当S7与半胱氨酸结合,并连接到包裹多柔比星的脂质纳米粒子(LNPs)表面时,能增强LNPs对胶质瘤的靶向性,并在U251胶质母细胞瘤小鼠异种移植模型中提高生存率。
T26366L Prasterone sulfate sodium hydrate

Sodium dehydroepiandrosterone sulfate,Prasterone sulfate sodium salt dihydrate,5-Androsten-3β-ol-17-one sulfate sodium salt dihydrate

Others Others
Prasterone is an endogenous steroid hormone. Prasterone acts as an agonist at ERβ, NMDA, and σ1 receptors, a partial agonist at ERα and AR, and antagonist at GABA-A receptors. It displays a variety of biologocial activities, including enhancing working me
T37435 PACAP-related Peptide (rat) (trifluoroacetate salt)

PACAP GPCR/G Protein
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica...
T60421 Antitumor agent-68

Others Others
Antitumor agent-68 是一种有效的微管蛋白抑制剂,具有良好的抗肿瘤活性,对宫颈癌细胞系 HeLa 和乳腺癌细胞系 MCF-7 细胞的IC50值分别为 3.6 和 3.8 μM。Antitumor agent-68 以剂量依赖的方式表现出良好的 ROS 和DPPH 自由基的清除活性。
TP1554 HPV16 E7 (86-93)

This is amino acids 86 to 93 fragment of the human papilloma virus (HPV) type 16 oncoprotein E7. This HPV16-encoded peptide has very high affinity of binding to the HLA-A*0201 molecule.This immunogenic fragment may be used in vaccines for the prevention a
T76997 Socazolimab

Socazolimab (ZKAB001) 是一种针对PD-L1的单克隆抗体,在治疗复发或转移性宫颈癌方面展现了持久的安全性和有效性。此外,Socazolimab 也被认为在小细胞肺癌、食管鳞状细胞癌 (ESCC)、晚期尿路上皮癌及骨肉瘤治疗中具有潜在应用价值。
T36195 CAY10744

Others Others
CAY10744 is a topoisomerase II-α poison.1 It inhibits topoisomerase II-α by 78.9% when used at a concentration of 20 μM. CAY10744 is selective for topoisomerase II-α over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 μM. It inhibits proliferation of HCT15 colon, T47D breast, DU145 prostate, and HeLa cervical cancer cells (IC50s = 0.014, 0.00267, 0.072, and 2.46 μM, respectively). CAY10744 induces apoptosis in T47D cells when used at concentrations of 10 and 30 μM. CAY1074...
T36404 PRLX-93936

Others Others
PRLX-93936 is an analog of erastin that has antitumor activity. It inhibits the hypoxia-inducible factor 1 (HIF-1) signaling pathway under hypoxic conditions (IC50 = 0.09 μM in a cell-based reporter assay). PRLX-93936 (1 μM) also inhibits hypoxia-induced increases in HIF-1α expression in ME-180 cervical cancer cells. It inhibits the growth of HT-1080 fibrosarcoma, OVCAR-5 ovarian cancer, BJELR tumorigenic primary fibroblast, and PANC-1 pancreatic cancer cells with IC50 values of less than 100 nM...
T35687 Collismycin A

Others Others
Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria (MICs = 6.25 and 100 μg/ml) and fungi (MICs = 12.5-100 μg/ml). It inhibits proliferation of A549 lung, HCT116 colon, and HeLa cervical cancer cells (IC50s = 0.3, 0.6, and 0.3 μM, respectively) and NIH373 fibroblasts (IC50 = 56.6 μM) but not MDA-MD-231 breast canc...
T71279 BPR1K653

Others Others
BPR1K653 is a potent Aurora kinase inhibitor with potential anticancder activity. BPR1K653 specifically inhibited the activity of Aurora-A and Aurora-B kinase at low nano-molar concentrations in vitro. BPR1K653 was potent in targeting a variety of cancer cell lines regardless of the tissue origin, p53 status, or expression of MDR1. At the cellular level, BPR1K653 induced endo-replication and subsequent apoptosis in both MDR1-negative and MDR1-positive cancer cells. Importantly, it showed potent ...
T68249 IRC-083927 HCl

Others Others
IRC-083927 HCl is novel and potent microtubule inhibitor with potential anticancer activity. IRC-083927 inhibits the tubulin polymerization by a binding to the colchicine site. IRC-083927 inhibits in vitro cell growth of human cancer cell lines in the low nanomolar range. More interesting, it remains highly active against cell lines resistant to microtubule-interacting agents (taxanes, Vinca alkaloids, or epothilones). Chronic oral treatment with IRC-083927 (5 mg/kg) inhibits the growth of two h...
T83854 BRC4wt TFA

BRC4wt是一种从人类BRCA2的BRC4重复区(1521-1536)衍生而来的乙酰化肽,并且是BRCA2与RAD51之间的蛋白质-蛋白质相互作用的抑制剂。当与阳离子穿膜肽(Arg)9结合时,BRC4wt缩短了体外DNA复制轨迹长度,并降低了由DNA拓扑异构酶I抑制剂坎普特西汀引起的DNA损伤的同源修复频率,同时也增强了聚(ADP-核糖)聚合酶(PARP)抑制剂奥拉帕尼在HeLa人类宫颈癌细胞和U2OS人类骨肉瘤细胞中诱导的细胞死亡,但在非癌症细胞hTERT RPE-1、MRC-5或MCF-10A中则不然。
T83910 S1PL-IN-31

Sphingosine-1-Phosphate Lyase Inhibitor 31,S1PL Inhibitor 31,S1P Lyase Inhibitor 31

Others Others
S1PL-IN-31是一种鞘氨醇-1-磷酸(S1P)裂解酶的抑制剂(IC50 = 210 nM),同时也是Smoothened(Smo)受体的对抗剂(IC50 = 440 nM)。在体内,S1PL-IN-31 (每天2 mg/kg)能够防止实验性自身免疫性脑炎(EAE)模型大鼠中,由髓鞘少突胶质细胞糖蛋白(MOG)肽段MOG29-152诱发的颈部及胸部淋巴细胞渗透和神经肌肉虚弱。该化合物降低了大鼠的淋巴细胞总数及CD4+ T细胞、CD8+ T细胞和B细胞的水平。S1PL-IN-31 (每天3及10 mg/kg剂量)在雄性和雌性大鼠心脏和淋巴结中增加了S1P水平,并且在雌性大鼠中降低了心率。
T36346 Ac-VEID-AMC (ammonium acetate salt)

Others Others
Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis.1It has also been reported to be cleaved by related proteases, including caspase-8.2Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. 1.Talanian, R.V., Quinlan, C., Trautz, S., et al.Substrate specificities of caspase family proteasesJ. Biol. Chem.272(15)9...

化合物

Valethamate bromide
Cat.No: T0023
Synonym: Ediposin,Epidozin,戊沙溴铵,Epidosin,Resitan
Target: Others
RAMB4
Cat.No: T12579
Synonym: PTP1B-IN-9
Target: Proteasome
Buformin hydrochloride
Cat.No: T20029
Synonym: NSC528218,NSC-528218,盐酸丁双胍,NSC 528218
Target: AMPK
Tyrphostin B44, (+) enantiomer
Cat.No: T22450
Synonym: 酪氨酸磷酸化抑制剂AG 835
Target: EGFR
Cdc7-IN-7c
Cat.No: T23867
Synonym: Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c
Target: CDK
INI-43
Cat.No: T27612
Synonym: INI 43,INI43
Target: Others
HPV16 E7 (86-93) acetate
Cat.No: TP1554L
Synonym: HPV16 E7 (86-93) acetate(160212-93-1 Free base)
Target: Others
Minnelide
Cat.No: T12042
Synonym:
Target: Apoptosis, Virus Protease
Hydroxyprogesterone caproate
Cat.No: T6858
Synonym: Primolut Depot,Delalutin,Hormofort,己酸孕酮,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate
Target: Autophagy
TG-89
Cat.No: T20742
Synonym:
Target: FLT, c-RET, JAK
VIP(6-28)(human, rat, porcine, bovine) acetate
Cat.No: TP1283L
Synonym:
Target: Others
ABI-1968 PM
Cat.No: T67786
Synonym:
Target: Others
JMJD6 inhibitor WL12
Cat.No: T9939
Synonym: 2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-,ZINC6733033
Target: Others
DIF-3
Cat.No: T60485
Synonym:
Target: Others
Sabizabulin
Cat.No: T17228
Synonym: ABI-231,VERU-111
Target: Microtubule Associated
Ro 90-7501
Cat.No: T16773
Synonym: RO-90-7501
Target: Apoptosis, Phosphatase, ATM/ATR, Gamma-secretase
CID-5056270
Cat.No: T23888
Synonym:
Target: ROCK
Norgestrel
Cat.No: T2597
Synonym: 甲基炔诺酮,SH-850,FH 122-A,炔诺孕酮,WY-3707,SH-70850
Target: Estrogen/progestogen Receptor, Reactive Oxygen Species
Lirilumab
Cat.No: T77423
Synonym: ONO-4483,IPH2102
Target: Virus Protease
Elezanumab
Cat.No: T76863
Synonym: AE12-1Y-QL,ABT-555
Target: TGF-beta/Smad
Sanazole
Cat.No: T34508
Synonym: AK2123,AK-2123,AK 2123
Target: Others
ALRT 1550
Cat.No: T26601
Synonym: LG-1550,LGD-1550,ALRT-1550,LG1550,ALRT-550,ALRT1550
Target: Others
Zalypsis
Cat.No: T29202
Synonym: PM00104,PM 10450,PM-00104,PM 00104,PM10450,PM-10450
Target: Others
Gliotoxin monoacetate
Cat.No: T70594
Synonym:
Target: Others
HPV16 E7 (86-93) (TFA)
Cat.No: T76015
Synonym:
Target:
Cadonilimab
Cat.No: T76716
Synonym:
Target:
Oxypyrronium bromide
Cat.No: T25912
Synonym: L.D. 3055,Immetropan,LD 3055,LD3055,LD-3055
Target: Others
Myosin light chain kinase fragment 11-19 amide
Cat.No: T81732
Synonym: MLCK(11-19) amide
Target:
HPV18-IN-1
Cat.No: T60544
Synonym:
Target: Others
Zimberelimab
Cat.No: T76709
Synonym:
Target:
B-Raf IN 7
Cat.No: T60933
Synonym:
Target: Others
Pritumumab
Cat.No: T81400
Synonym:
Target:
Oxanosine
Cat.No: T68667
Synonym:
Target: Others
S7 TFA
Cat.No: T83741
Synonym: Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH
Target:
Prasterone sulfate sodium hydrate
Cat.No: T26366L
Synonym: Sodium dehydroepiandrosterone sulfate,Prasterone sulfate sodium salt dihydrate,5-Androsten-3β-ol-17-one sulfate sodium salt dihydrate
Target: Others
PACAP-related Peptide (rat) (trifluoroacetate salt)
Cat.No: T37435
Synonym:
Target: PACAP
Antitumor agent-68
Cat.No: T60421
Synonym:
Target: Others
HPV16 E7 (86-93)
Cat.No: TP1554
Synonym:
Target:
Socazolimab
Cat.No: T76997
Synonym:
Target:
CAY10744
Cat.No: T36195
Synonym:
Target: Others
PRLX-93936
Cat.No: T36404
Synonym:
Target: Others
Collismycin A
Cat.No: T35687
Synonym:
Target: Others
BPR1K653
Cat.No: T71279
Synonym:
Target: Others
IRC-083927 HCl
Cat.No: T68249
Synonym:
Target: Others
BRC4wt TFA
Cat.No: T83854
Synonym:
Target:
S1PL-IN-31
Cat.No: T83910
Synonym: Sphingosine-1-Phosphate Lyase Inhibitor 31,S1PL Inhibitor 31,S1P Lyase Inhibitor 31
Target: Others
Ac-VEID-AMC (ammonium acetate salt)
Cat.No: T36346
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T11363 Ganoderic acid F

Others Others
Ganoderic acid F 是一种灵芝酸。它具有抗肿瘤和抗转移的活性,与抑制血管生成和涉及细胞增殖和细胞死亡,致癌作用,氧化应激,钙信号传导和内质网应激的蛋白质改变等机制相关。
T5S1133 Ganoderic acid D

灵芝酸D,灵芝酸 D

Apoptosis; Sirtuin Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
Ganoderic acid D 是高度氧化的四环三萜,是灵芝的主要活性成分,可诱导 HeLa 人宫颈癌细胞凋亡。它上调 SIRT3的蛋白质表达并通过 SIRT3 诱导脱乙酰化的亲环蛋白 D 。它抑制结肠癌细胞的能量重编程,包括结肠癌细胞中的葡萄糖摄取,乳酸、丙酮酸和乙酰辅酶的产生。
T13475 β-Aminopropionitrile

3-氨基丙腈,3-Aminopropionitrile,BAPN

Others; Endogenous Metabolite Metabolism; Others
β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
T14046 Anandamide

花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Cannabinoid Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide) 是一种免疫调节剂,通过大麻素受体 CB1 和 CB2 起作用,还通过中枢神经系统中的其他靶点起作用,如 GPR18/GPR55。
T3425 Polyphyllin G

重楼皂苷VII,Polyphyllin VII,Polyphyllin VII,Y-0166,重楼皂苷G

Others Others
Polyphyllin G (Polyphyllin VII) 是从Paris yunnanensis 的根茎中分离出来的,具有抗菌活性,抑制革兰氏阳性和革兰氏阴性细菌的生长。它是polyphyllin 家族的主要成员,对肺癌、乳腺癌、结直肠癌、宫颈癌、肝细胞癌和骨肉瘤等多种癌症具有很强的抗癌活性。
TN6730 Epoxyazadiradione

NF-κB NF-κB
Epoxyazadiradione 是从印楝果实中得到的柠檬苦素。它能够可逆的、非竞争性的抑制人类、约氏疟原虫、疟原虫的互变异构酶活性。它具有抗疟原虫和人类 MIF 诱导的促炎反应的潜力。
T4036 Solasodine

Solancarpidine,Purapuridine,澳洲茄铵,Solasodin

Apoptosis; Others; E1/E2/E3 Enzyme; Antifungal Apoptosis; Microbiology/Virology; Others; Ubiquitination
Solasodine (Purapuridine) 是存在于茄科植物中的一种类固醇生物碱。它具有神经保护、降压、抗真菌、抗癌、抗动脉粥样硬化、抗雄激素和抗炎活性。
T8787 Drotaverine hydrochloride

PDE Metabolism
Drotaverine hydrochloride 是磷酸二酯酶 4 (PDE4)的抑制剂,也是 L 型电压依赖钙通道(L-VDCC)的阻滞剂,可阻断3',5'-环腺苷单磷酸的降解。它在体内有抗痉挛效果,但无抗胆碱能的效果。
TN1393 (-)-Anonaine

番荔枝碱

Apoptosis; Antioxidant; Parasite; Antifungal Apoptosis; Microbiology/Virology; oxidation-reduction
(-)-Anonaine 可从木兰科和安妮科的几个物种中提取出来,具有抗疟、抗菌、抗真菌、抗氧化、抗癌、抗抑郁和血管舒张的活性。(-)-Anonaine 通过 Bax 和 caspase 依赖性途径诱导人类宫颈癌(HeLa)细胞的凋亡,诱导 DNA 损伤并抑制人类肺癌 h1299细胞的生长和迁移。
TN1013 Cucurbitacin D

Apoptosis Apoptosis
Cucurbitacin D 是一种从 Ecballium elaterium (L.)分离出来的三萜类化合物,具有抗癌抗肿瘤活性,抑制转移性 PrC 中的葡萄糖摄取和乳酸产生,诱导独立于 ERK1/2 激活的炎症小体激活。 Cucurbitacin D 是巨噬细胞中的一种新的炎症小体激活剂,通过调节 JAK/STAT3、PI3K/Akt/mTOR 和 MAPK 信号通路抑制 HepG2 细胞增殖并诱导细胞凋亡, 可用于研究宫颈癌、白血病和前列腺癌。
T0122 Bergenin

Cuscutin,Bengenin,岩白菜素

Apoptosis; IL Receptor; Virus Protease; TNF; NF-κB; Antibacterial; NOD; Autophagy; Antifungal Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology; NF-κB
Bergenin (Bengenin) 是一种在许多药用植物中发现的多酚,有细胞保护和抗氧化作用。它还具有广泛的保肝、抗炎、抗肿瘤、抗病毒、抗真菌以及免疫调节作用。
TN7405 Ganolucidic acid E

Others Others
Ganolucidic acid E effectively suppresses the proliferation of three human cancer cell lines: Caco-2 (colon cancer), HepG2 (hepatocellular carcinoma), and HeLa (cervical cancer).
TN7414 10-Deacetylcephalomannine

Others Others
10-Deacetylcephalomannin exhibits activity against PS leukemia in vivo; however, its instability leads to an equilibrium mixture with its cytotoxic C-7 epimer. Additionally, 10-Deacetylcephalomannine demonstrates growth inhibitory effects on human cancer cell lines, including cervical HeLa adenocarcinoma.
TN4109 Ganolucidic acid A

HIV Protease Microbiology/Virology; Proteases/Proteasome
Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of 20-90 microM.
TN6010 Picrasidine S

Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria methicillin-resistant Staphylococcus
TN4102 Ganoderic acid AM1

Others Others
Ganoderic acid AM1 treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.8+/-0.7 microM.
T69368 GKK1032B

Others Others
GKK1032B is a fungal metabolite that has antiproliferative and antibacterial activities. GKK1032B inhibits the growth of HeLa S3 cervical and MCF-7 breast cancer cells and Vero cells. It also inhibits the growth of B. subtilis and M. tuberculosis.
TN2328 Zeylenone

Apoptosis; ERK; MAPK; Akt; PI3K; mTOR Apoptosis; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Zeylenone 是一种来自 Uvaria grandiflora的环己烯氧化物,具有抗肿瘤和抗癌细胞增殖活性,通过 PI3K/AKT/mTOR 和 MAPK/ERK 信号通路抑制宫颈癌细胞增殖,诱导细胞凋亡 (apoptosis)。
T80019 17-Hydroxyneomatrine

Others Others
17-Hydroxyneomatrine 是一种从苦参 (Sophora flavescens) 提取的化合物,有效抑制人宫颈癌Hela细胞生长,并展现抗菌、抗过敏、抗肿瘤、抗心律失常、消肿、利尿、免疫调节等多种生物活性。
T35609 19-O-Acetylchaetoglobosin A

Others Others
19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.1,2It inhibits actin polymerization in a cell-free assay when used at a concentration of 2 μM.219-O-Acetylchaetoglobosin A (3.2, 10, and 32 μg/ml) is cytotoxic to HeLa cervical cancer cells.1 1.Umeda, M., Ohtsubo, K., Saito, M., et al.Cytotoxicity of new cytochalasans from Chaetomium globosumExperientia31(4)435-438(1975) 2.Sekita, S., Yoshihira, ...
TMA1008 Ganoderic acid S

Others Others
A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the treatment or prophylaxis of colon ca
TN4194 Heliangin

IL Receptor; TNF; NF-κB; MAPK; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK; NF-κB
Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-κB pathway on LPS-induced RAW 264.7 cells. Heliangin has anti-cancer activity, it exhibits cytotoxicity against human oral epidermoid (
T75629 Ganoderic acid Mk

Others Others
Ganoderic acid Mk (GA-Mk)为来源于灵芝菌丝的三萜酸类化合物,能有效抑制细胞增殖,并通过线粒体途径诱导HeLa细胞的细胞凋亡(apoptosis),在宫颈癌研究中具有应用价值。
TN3968 Epifriedelanol acetate

Others Others
Epifriedelanol exhibits antibacterial activities. It also can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol and friedel
T79941 Antimycin A2c

Apoptosis Apoptosis
Anticanceragent 141(compound AE)是一种针对HPV感染宫颈癌具有抑制作用的抗霉素生物碱。该化合物能够抑制宫颈癌HeLa细胞的增殖并导致细胞周期在S期停滞。Anticanceragent 141破坏线粒体功能,诱导caspase依赖性细胞凋亡,并激活ROS介导的泛素依赖性蛋白酶体系统,进而引起E6/E7癌蛋白的降解。
T36448 (E)-Ajoene

Others Others
(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth...
T36000 3-Hydroxyterphenyllin

Others Others
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...

天然产物

Ganoderic acid F
Cat.No: T11363
Synonym:
Target: Others
Ganoderic acid D
Cat.No: T5S1133
Synonym: 灵芝酸D,灵芝酸 D
Target: Apoptosis, Sirtuin
β-Aminopropionitrile
Cat.No: T13475
Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN
Target: Others, Endogenous Metabolite
Anandamide
Cat.No: T14046
Synonym: 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide
Target: Cannabinoid Receptor, Endogenous Metabolite
Polyphyllin G
Cat.No: T3425
Synonym: 重楼皂苷VII,Polyphyllin VII,Polyphyllin VII,Y-0166,重楼皂苷G
Target: Others
Epoxyazadiradione
Cat.No: TN6730
Synonym:
Target: NF-κB
Solasodine
Cat.No: T4036
Synonym: Solancarpidine,Purapuridine,澳洲茄铵,Solasodin
Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal
Drotaverine hydrochloride
Cat.No: T8787
Synonym:
Target: PDE
(-)-Anonaine
Cat.No: TN1393
Synonym: 番荔枝碱
Target: Apoptosis, Antioxidant, Parasite, Antifungal
Cucurbitacin D
Cat.No: TN1013
Synonym:
Target: Apoptosis
Bergenin
Cat.No: T0122
Synonym: Cuscutin,Bengenin,岩白菜素
Target: Apoptosis, IL Receptor, Virus Protease, TNF, NF-κB, Antibacterial, NOD, Autophagy, Antifungal
Ganolucidic acid E
Cat.No: TN7405
Synonym:
Target: Others
10-Deacetylcephalomannine
Cat.No: TN7414
Synonym:
Target: Others
Ganolucidic acid A
Cat.No: TN4109
Synonym:
Target: HIV Protease
Picrasidine S
Cat.No: TN6010
Synonym:
Target:
Ganoderic acid AM1
Cat.No: TN4102
Synonym:
Target: Others
GKK1032B
Cat.No: T69368
Synonym:
Target: Others
Zeylenone
Cat.No: TN2328
Synonym:
Target: Apoptosis, ERK, MAPK, Akt, PI3K, mTOR
17-Hydroxyneomatrine
Cat.No: T80019
Synonym:
Target: Others
19-O-Acetylchaetoglobosin A
Cat.No: T35609
Synonym:
Target: Others
Ganoderic acid S
Cat.No: TMA1008
Synonym:
Target: Others
Heliangin
Cat.No: TN4194
Synonym:
Target: IL Receptor, TNF, NF-κB, MAPK, Prostaglandin Receptor
Ganoderic acid Mk
Cat.No: T75629
Synonym:
Target: Others
Epifriedelanol acetate
Cat.No: TN3968
Synonym:
Target: Others
Antimycin A2c
Cat.No: T79941
Synonym:
Target: Apoptosis
(E)-Ajoene
Cat.No: T36448
Synonym:
Target: Others
3-Hydroxyterphenyllin
Cat.No: T36000
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-03375 Stathmin-2 Protein, Rat, Recombinant (His)

Superior cervical ganglion-10 protein,Stmn2,Stathmi...

Rat E. coli
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. Stathmin-2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.7 kDa and the accession number is P21818.
TMPH-01709 Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc)

Mucin-5 subtype B, tracheobronchial,Mucin-5B,Sublingual glan...

Human E. coli
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is Q9HC84.
TMPY-00365 GALNT7 Protein, Human, Recombinant (His)

GalNAcT7,polypeptide N-acetylgalactosaminyltransferase 7,GAL...

Human HEK293 Cells
GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either discrete genetic perturbation or epigenetic dysregulation. GALNT7 acts as a glycosyltransferase in protein O-glycosylation, involving in the occurrence and development of CRC. GALNT7 silencing significantly attenuated the proliferation, clonogenicity and migration of LSCC cells a...
TMPK-00479 AGER Protein, Cynomolgus, Recombinant (His)

AGER,RAGE,SCARJ1

Cynomolgus HEK293 Cells
The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides novel evidence for a potential role of AGER in bridging human papillomavirus (HPV)-induced inflammation and cervical cancer.
TMPK-01466 HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)

Human papillomavirus type 16,E6,HPV16

Human HEK293 Cells
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer.
TMPK-01467 HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)

HPV16,E6,Human papillomavirus type 16

Human HEK293 Cells
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer.
TMPK-01504 HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi)

MHC,HPV16,E7

Human HEK293 Cells
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.
TMPK-01506 HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi)

HPV16,E7,MHC

Human HEK293 Cells
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.
TMPK-00944 ST3GAL4 Protein, Human, Recombinant (HA, His)

STZSIAT4,ST-4,SIAT4,ST3GAL4,SAT3,CGS23,SIAT4C,Gal-NAc 6S,NAN...

Human HEK293 Cells
ST3GAL4 gene expression is altered in different cancer types, including cervical cancer. Several mRNA transcripts have been reported for this gene. ST3GAL4 encodes for β‑galactosidase α‑2,3‑sialyltransferase 4, involved in the biosynthesis of the tumour antigens sLe(x) and sulfo‑sLe(x).
TMPK-01505 HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated

E7,MHC,HPV16

Human HEK293 Cells
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.
TMPY-00575 ULBP-6 Protein, Human, Recombinant (His)

RAET1L,retinoic acid early transcript 1L,ULBP6

Human HEK293 Cells
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPK-00495 CADM3 Protein, Cynomolgus, Recombinant (His)

NECL1,IGSF4B,CADM3,TSLC1-like 1,GSF4B,NECL-1,TSLL1,SynCAM3,m...

Cynomolgus HEK293 Cells
Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compa...
TMPY-00190 ULBP-6 Protein, Human, Recombinant (hFc)

retinoic acid early transcript 1L,RAET1L,ULBP6

Human HEK293 Cells
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cel...
TMPJ-00283 Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated

G250,P54/58N,Carbonic Anhydrase IX,CA9,Carbonate dehydratase...

Human HEK293 Cells
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC...
TMPY-06226 SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)

solute carrier family 39 member 6

Cynomolgus HEK293 Cells
Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as a...
TMPY-03795 EIF5A2 Protein, Human, Recombinant (His)

eIF5AII,eukaryotic translation initiation factor 5A2,EIF-5A2

Human E. coli
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic targe...
TMPH-03753 MYLK Protein, Human, Recombinant (His)

MYLK,Myosin light chain kinase, smooth muscle,Telokin,Kinase...

Human E. coli
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl...

重组蛋白

Stathmin-2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03375
Species: Rat
Expression System: E. coli
Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01709
Species: Human
Expression System: E. coli
GALNT7 Protein, Human, Recombinant (His)
Cat.No: TMPY-00365
Species: Human
Expression System: HEK293 Cells
AGER Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00479
Species: Cynomolgus
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01466
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01467
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01504
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01506
Species: Human
Expression System: HEK293 Cells
ST3GAL4 Protein, Human, Recombinant (HA, His)
Cat.No: TMPK-00944
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01505
Species: Human
Expression System: HEK293 Cells
ULBP-6 Protein, Human, Recombinant (His)
Cat.No: TMPY-00575
Species: Human
Expression System: HEK293 Cells
CADM3 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00495
Species: Cynomolgus
Expression System: HEK293 Cells
ULBP-6 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00190
Species: Human
Expression System: HEK293 Cells
Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00283
Species: Human
Expression System: HEK293 Cells
SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-06226
Species: Cynomolgus
Expression System: HEK293 Cells
EIF5A2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03795
Species: Human
Expression System: E. coli
MYLK Protein, Human, Recombinant (His)
Cat.No: TMPH-03753
Species: Human
Expression System: E. coli
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