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Search Results for " canine "

66

抑制剂 & 化合物

6

天然产物

180

重组蛋白

4

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
TP1098 Motilin, canine

Motilin (canine)

Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.
TP1085L Neuromedin N acetate(92169-45-4 free base)

Neuromedin N (rat, mouse, porcine, canine) acetate

Dopamine Receptor GPCR/G Protein; Neuroscience
Neuromedin N acetate(92169-45-4 free base) 是一种神经肽,其衍生自与神经降压素相同的前体多肽,具有相似但略有不同的表达和作用。Neuromedin N 是多巴胺 D2 受体激动剂与大鼠新纹状体膜结合的有效调节剂。
TP1610 Secretin, canine

Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Canine secretin can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.
TP1174 Endothelin-2 (49-69), human

Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2

Others Others
Endothelin-2 (49-69), human (Human endothelin-2) 是一种由 21 个氨基酸组成的血管活性肽。它可与 G 蛋白连接的跨膜受体,ET-RA 和ET-RB 结合。
TP1085 Neuromedin N

Neuromedin N (rat, mouse, porcine, canine)

Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.
TP1016 Aviptadil

Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine),阿肽地尔

Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction.
TP2143 Endothelin-2 (49-69), human TFA

Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA

Others Others
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.
T16347 NS3623

Potassium Channel Membrane transporter/Ion channel
NS3623 是 hERG1 (KV11.1)钾通道激活剂,激活IKr 和Ito 电流,具有抗心律失常作用。NS3623也是 hERG1 通道抑制剂。
T80148 GRP (14-27) (human, porcine, canine)

Bombesin Receptor GPCR/G Protein
GRP (14-27) (human, porcine, canine) 表现为铃蟾肽受体配体。其特异性结合受到 GTP 和 GDP 的抑制作用,但 GMP 对此无影响。
T0696 Naftopidil

KT-611,萘哌地尔,BM-15275

Adrenergic Receptor GPCR/G Protein; Neuroscience
Naftopidil (KT-611) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂,对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM 、1.2 nM。它具有抗增殖活性,可用于研究前列腺增生。
T76651 Peptide YY (13-36) (canine, mouse, porcine, rat)

Peptide YY (13-36) (canine, mouse, porcine, rat) 是 Y2受体的激动剂。
T8236 RHC 80267

U-57908

Others; Phospholipase; COX; Acyltransferase; AChR Immunology/Inflammation; Metabolism; Neuroscience; Others
RHC 80267 (U-57908) 是一种选择性二酰基甘油脂酶(DAGL)抑制剂,对犬血小板的IC50为 4 μM。它抑制COX 活性和磷脂酰胆碱的水解,还抑制胆碱酯酶活性,IC50为 4 μM,增强乙酰胆碱引起的松弛。
T6600 Naftopidil dihydrochloride

KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl

5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Naftopidil dihydrochloride (KT-611 2HCl) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂,对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性,可用于研究前列腺增生。
TP1016L Aviptadil Acetate

醋酸阿肽地尔,阿肽地尔,Vasoactive Intestinal Peptide acetate salt

RAAS; SARS-CoV Endocrinology/Hormones; Microbiology/Virology
Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) 是模拟血管活性肠多肽类似物,具有血管舒张效应。它可诱导肺血管舒张并抑制血管 SMC 的增殖和血小板聚集。它可用于研究 SARS-CoV-2 引起的肺纤维化、肺动脉高压和呼吸衰竭。
T9220 Naftopidil hydrochloride

1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Naftopidil hydrochloride (BM-15275 hydrochloride) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂,对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力 Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性,可用于研究前列腺增生。
T22893 L-168049

L-168,049

Glucagon Receptor GPCR/G Protein
L-168049 是一种选择性和非竞争性人胰高血糖素受体拮抗剂,对人、鼠和犬的 IC50 分别为 3.7 nM、63 nM 和 60 nM。
T15209 Elobixibat

AZD 7806,A 3309

Others Others
Elobixibat (A 3309) 是回肠胆汁酸转运蛋白的抑制剂(小鼠、人和犬 IBAT 的 IC50:0.13 nM、0.53 nM 和 5.8 nM)。 Elobixibat 可用于慢性特发性便秘的研究。
T0489 Flutamide

SCH 13521,氟他胺

Androgen Receptor Endocrinology/Hormones
Flutamide (SCH 13521) 是一种抗雄激素化合物,在啮齿动物和犬科动物中的效力与环丙孕酮大致相同。
T28895 T-0509

T 0509,T0509

Adrenergic Receptor GPCR/G Protein; Neuroscience
T-0509 是一种选择性 beta 1 受体激动剂,可增加犬心室肌的肌力,选择性下调大鼠心脏 β 1-肾上腺素受体。
T12321 ORM-10103

Calcium Channel Membrane transporter/Ion channel; Metabolism
ORM-10103 是一种新型有效且具有选择性的 Na+/Ca2+ 交换体 (NCX) 抑制剂。ORM-10103 对 NCX 电流有抑制作用,在 -80 和 20 mV 下的 IC50 的估算值分别为 55 和 67 nM,可减少犬心脏的早期和延迟后去极化。
T17030 Tegoprazan

ATPase; Proton pump Membrane transporter/Ion channel
Tegoprazan 是一种口服有效的、高选择性胃 H+/K+-ATP 酶 (H+/K+-ATPase) 抑制剂,能够控制胃酸分泌和运动,在体外检测的对猪、犬、人的 H+/K+-ATP 酶的 IC50为0.29-0.52 μM。
T82525L DT-2 acetate

DT-2 acetate(1220985-78-3 Free base)

PKA Tyrosine Kinase/Adaptors
DT-2 acetate 是一种具有选择性的 cGMP 依赖性蛋白激酶 (PKG) 抑制剂,是一种靶向犬胸腺细胞的小鼠单克隆抗体。DT-2 acetate 抑制 PKG 催化的磷酸化 ,逆转8-Br-cGMP诱导的扩张,可用于研究免疫疾病。
T17006 TC-I 2014

TRP/TRPV Channel Membrane transporter/Ion channel
TC-I 2014 是一种口服有效的、强效的、苯并咪唑类的、 TRPM8 的拮抗剂,其对犬类、人和大鼠通道的 IC50 值分别为 0.8 nM, 3.0 nM 和 4.4 nM。在疼痛动物模型中具有抗痛觉超敏作用。
T20714 Levolansoprazole

左旋兰索拉唑,(S)-Lansoprazole,(-)-Lansoprazole

Proton pump Membrane transporter/Ion channel
Levolansoprazole ((S)-Lansoprazole) 是一种质子泵抑制剂,不可逆地抑制壁细胞中 H+/K+ 刺激的 ATPase 泵 (IC50: 5.2 µM)。它还抑制分离的犬壁细胞中的酸形成(IC50:82 µM)。 (R)-和 (S)-兰索拉唑均具有药理活性,具有相似的效力。
T7339 Angiotensin (1-7)

Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO

RAAS; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性,因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮,是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大,并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。
T1325 Carprofen

卡洛芬,Ridamyl,Imadyl,Rimadyl

FAAH; COX; Autophagy Autophagy; Immunology/Inflammation; Metabolism; Neuroscience
Carprofen (Ridamyl) 是多靶点FAAH/COX 抑制剂,能够抑制 COX-2,COX-1 和 FAAH 的活性,IC50值分别为 3.9 μM,22.3 μM 和 78.6 μM。它是一种丙酸衍生物和非甾体抗炎药,具有抗炎、镇痛和解热活性。
T1546 Nitazoxanide

NSC 697855,硝唑尼特

Others; Influenza Virus; Parasite; Autophagy Autophagy; Microbiology/Virology; Others
Nitazoxanide (NSC-697855) 是一种广谱驱虫剂,对感染动物和人类的各种蠕虫、原生动物和肠道细菌都具有作用活性。 它在无菌培养中抑制Giardia lamblia 滋养体增殖,IC50为 2.4 μM。它可研究寄生虫性胃肠炎,具有抗病毒特性。
T15487 HMR 1556

Others Others
HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).
T27278 Epsiprantel

Others Others
Epsiprantel is an antiparasitic for canine worms.
T31030 CP 71362

CP71362

Others Others
CP 71362 is a selective pentapeptide renin inhibitor for canine enzymes.
TC0008 Desoxycorticosterone pivalate

DOCP

Others Others
Deoxycorticosterone (DOCP) is a mineralocorticoid and is an analog of deoxycorticosterone. Deoxycorticosterone pivalate is used in the treatment of canine low adrenal cortex hormones.
T76816 Lokivetmab

Lokivetmab(Anti-Canine IL31 Recombinant Antibody)为针对犬特应性皮炎(AD)研究的抗犬IL-31单克隆抗体。
T13340 Win-62005

Others Others
Win-62005 is an inhibitor of cyclic AMP phosphodiesterase III (PDE III)(Kis: 25 and 26 nM for rat heart and canine aorta).
T71421 Bemoradan

Others Others
Bemoradan is an inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue
T70510 CVS-1123

Others Others
CVS-1123 is a direct thrombin inhibitor, preventing occlusive arterial and venous thrombosis in a canine model of vascular injury.
T26312 Uredofos

Sansalid,RH 32565,RH32565,RH-32565

Others Others
Uredofos 是一种广谱驱虫药,它犬绦虫、蛔虫、钩虫和鞭虫都非常有效。
T76932 Blontuvetmab

Blontuvetmab (AT 004),犬源化CD20单克隆抗体,主要用于研究犬B细胞淋巴瘤。
T41020 Melarsomine dihydrochloride

Others Others
Melarsomine dihydrochloride is a trivalent arsenical compound employed as an adulticide in the treatment of canine heartworm disease and other helminth infections. It is also utilized for research purposes in the study of these conditions.
T38686 Melarsomine

Others Others
Melarsomine, a trivalent arsenical compound, is employed as an adulticide for canine heartworm disease and other helminth infections. It has significant utility in the research of these conditions.
T78300 Anivovetmab

KIND-030

Anivovetmab (KIND-030)为针对细小病毒主要衣壳蛋白的IgG2型单克隆抗体,潜在应用于研究犬细小病毒感染。
T71601 CU-2010

Others Others
CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a canine model.
TP2010 Kisspeptin 10 (dog)

Endogenous ligand for the canine KISS1 receptor (Kisspeptin receptor or GPR54). Stimulates section of luteinizing hormone, follicle stimulating hormone and estradiol in vivo.
T28884 SUN-C5174

SUNC-5174

Others Others
SUN-C5174 is a sleective 5-HT2 antagonist (pA2=8.98+/-0.06). SUN C5174 showed a marked inhibitory effect on the platelet aggregation induced by serotonin in combination with collagen and adenosine diphosphate (ADP) in canine or human platelet-rich plasma
T16906 Sograzepide

YM-220,Netazepide,YF 476

Others Others
Sograzepide is an effective and highly selective Gastrin/CCK-B antagonist (IC50: 0.1 nM), has an inhibitory effect on Gastrin/CCK-A activity (IC50: 502 nM). Sograzepide replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine, and cloned human Gastrin/CCK-B receptors (Ki: 0.068, 0.62 and 0.19 nM, respectively).
T70379 PF-04479745 tartrate

Others Others
PF-04479745, also known as PF-4479745, is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measurable functional agonism at the key selectivity targets 5-HT2A and 5-HT2B in relevant tissue-based assay systems.
T35463 (±)14(15)-EET

(±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET

Others Others
(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) induced by oxidized LDL in primary rat pulmonary artery endothelial cells (RPAECs) when used at a concentration of 1 μM.[3] (±)14(15)-EET induces dilation of preconstricted isolated canine coronary arterioles (EC50 = 0.2 pM).[4] It reduces myocardial infarct size as a percentage o...
T27038 CL385319 HCl

CL-385319,CL385319 hydrochloride,CL 385319,CL385319

Others Others
CL385319 is a potent inhibitor of H5N1 avian influenza A virus infection by blocking viral entry. CL-385319 is effective in inhibiting infection of highly pathogenic H5N1 influenza A virus in Madin-Darby Canine Kidney (MDCK) cells with an IC50 of 27.03±2.
T80990 Thrombostatin cont-1

Thrombostatin cont-1为缓激肽代谢物,归属于凝血抑制素类似物。该化合物在犬颈动脉球囊成形术损伤模型中,能有效减少血小板活化。
T71426 STA-1474

Others Others
STA-1474 is a water soluble prodrug of ganetespib (formerly STA-9090). STA-1474 will metabolized to Ganetespib, which is a potent HSP90 inhibitor previously shown to kill canine tumor cell lines in vitro and inhibit tumor growth in the setting of murine xenografts. The purpose of the following study was to extend these observations and investigate the safety and efficacy of STA-1474 in dogs with spontaneous tumors.
T72515 Elobixibat hydrate

A 3309 hydrate ; AZD 7806 hydrate,AZD 7806 hydrate,A 3309 hydrate

Others Others
Elobixibat hydrate是一有效胆汁酸转运体(IBAT)抑制剂,对人类IBAT、小鼠IBAT及犬类IBAT的IC50值分别为0.53±0.17 nM、0.13±0.03 nM和5.8±1.6 nM。适用于研究老年慢性功能性便秘(CIC)。

化合物

Motilin, canine
Cat.No: TP1098
Synonym: Motilin (canine)
Target:
Neuromedin N acetate(92169-45-4 free base)
Cat.No: TP1085L
Synonym: Neuromedin N (rat, mouse, porcine, canine) acetate
Target: Dopamine Receptor
Secretin, canine
Cat.No: TP1610
Synonym:
Target:
Endothelin-2 (49-69), human
Cat.No: TP1174
Synonym: Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2
Target: Others
Neuromedin N
Cat.No: TP1085
Synonym: Neuromedin N (rat, mouse, porcine, canine)
Target:
Aviptadil
Cat.No: TP1016
Synonym: Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine),阿肽地尔
Target:
Endothelin-2 (49-69), human TFA
Cat.No: TP2143
Synonym: Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA
Target: Others
NS3623
Cat.No: T16347
Synonym:
Target: Potassium Channel
GRP (14-27) (human, porcine, canine)
Cat.No: T80148
Synonym:
Target: Bombesin Receptor
Naftopidil
Cat.No: T0696
Synonym: KT-611,萘哌地尔,BM-15275
Target: Adrenergic Receptor
Peptide YY (13-36) (canine, mouse, porcine, rat)
Cat.No: T76651
Synonym:
Target:
RHC 80267
Cat.No: T8236
Synonym: U-57908
Target: Others, Phospholipase, COX, Acyltransferase, AChR
Naftopidil dihydrochloride
Cat.No: T6600
Synonym: KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl
Target: 5-HT Receptor, Adrenergic Receptor
Aviptadil Acetate
Cat.No: TP1016L
Synonym: 醋酸阿肽地尔,阿肽地尔,Vasoactive Intestinal Peptide acetate salt
Target: RAAS, SARS-CoV
Naftopidil hydrochloride
Cat.No: T9220
Synonym: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride
Target: Adrenergic Receptor
L-168049
Cat.No: T22893
Synonym: L-168,049
Target: Glucagon Receptor
Elobixibat
Cat.No: T15209
Synonym: AZD 7806,A 3309
Target: Others
Flutamide
Cat.No: T0489
Synonym: SCH 13521,氟他胺
Target: Androgen Receptor
T-0509
Cat.No: T28895
Synonym: T 0509,T0509
Target: Adrenergic Receptor
ORM-10103
Cat.No: T12321
Synonym:
Target: Calcium Channel
Tegoprazan
Cat.No: T17030
Synonym:
Target: ATPase, Proton pump
DT-2 acetate
Cat.No: T82525L
Synonym: DT-2 acetate(1220985-78-3 Free base)
Target: PKA
TC-I 2014
Cat.No: T17006
Synonym:
Target: TRP/TRPV Channel
Levolansoprazole
Cat.No: T20714
Synonym: 左旋兰索拉唑,(S)-Lansoprazole,(-)-Lansoprazole
Target: Proton pump
Angiotensin (1-7)
Cat.No: T7339
Synonym: Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO
Target: RAAS, Endogenous Metabolite
Carprofen
Cat.No: T1325
Synonym: 卡洛芬,Ridamyl,Imadyl,Rimadyl
Target: FAAH, COX, Autophagy
Nitazoxanide
Cat.No: T1546
Synonym: NSC 697855,硝唑尼特
Target: Others, Influenza Virus, Parasite, Autophagy
HMR 1556
Cat.No: T15487
Synonym:
Target: Others
Epsiprantel
Cat.No: T27278
Synonym:
Target: Others
CP 71362
Cat.No: T31030
Synonym: CP71362
Target: Others
Desoxycorticosterone pivalate
Cat.No: TC0008
Synonym: DOCP
Target: Others
Lokivetmab
Cat.No: T76816
Synonym:
Target:
Win-62005
Cat.No: T13340
Synonym:
Target: Others
Bemoradan
Cat.No: T71421
Synonym:
Target: Others
CVS-1123
Cat.No: T70510
Synonym:
Target: Others
Uredofos
Cat.No: T26312
Synonym: Sansalid,RH 32565,RH32565,RH-32565
Target: Others
Blontuvetmab
Cat.No: T76932
Synonym:
Target:
Melarsomine dihydrochloride
Cat.No: T41020
Synonym:
Target: Others
Melarsomine
Cat.No: T38686
Synonym:
Target: Others
Anivovetmab
Cat.No: T78300
Synonym: KIND-030
Target:
CU-2010
Cat.No: T71601
Synonym:
Target: Others
Kisspeptin 10 (dog)
Cat.No: TP2010
Synonym:
Target:
SUN-C5174
Cat.No: T28884
Synonym: SUNC-5174
Target: Others
Sograzepide
Cat.No: T16906
Synonym: YM-220,Netazepide,YF 476
Target: Others
PF-04479745 tartrate
Cat.No: T70379
Synonym:
Target: Others
(±)14(15)-EET
Cat.No: T35463
Synonym: (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
Target: Others
CL385319 HCl
Cat.No: T27038
Synonym: CL-385319,CL385319 hydrochloride,CL 385319,CL385319
Target: Others
Thrombostatin cont-1
Cat.No: T80990
Synonym:
Target:
STA-1474
Cat.No: T71426
Synonym:
Target: Others
Elobixibat hydrate
Cat.No: T72515
Synonym: A 3309 hydrate ; AZD 7806 hydrate,AZD 7806 hydrate,A 3309 hydrate
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN5768 Chiricanine A

Chiricanine A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5768,CAS号为 350593-30-5。
TN1485 Chicanine

Others; NF-κB; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; NF-κB; Others
Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.
T33817 Orellanine

2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one

Others Others
Orellanine 是一种从蘑菇 Cortinarius orellanus 中提取的肾毒性化合物。 Orellanine 强烈抑制 Madin-Darby 犬肾细胞和大鼠肝线粒体中大分子(蛋白质、RNA 和 DNA)的合成。
T2S2046 Bruceine A

Dihydrobrusatol,鸦胆子素 A,NSC31616

Antibiotic; Parasite Microbiology/Virology
Bruceine A (NSC-31616) 是一种从鸦胆子 (L.) 的干果中提取的天然类苦素化合物,有治疗犬巴贝斯虫病的潜力。
T27380 FR-198248

Others Others
FR-198248, a new anti-influenza agent, shows antiinfluenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro.
TN1875 Liriodenine

鹅掌揪碱

BCL; Caspase; p53 Apoptosis; Proteases/Proteasome
Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial ischaemia reperfusion, through inhibiti

天然产物

Chiricanine A
Cat.No: TN5768
Synonym:
Target:
Chicanine
Cat.No: TN1485
Synonym:
Target: Others, NF-κB, Prostaglandin Receptor
Orellanine
Cat.No: T33817
Synonym: 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one
Target: Others
Bruceine A
Cat.No: T2S2046
Synonym: Dihydrobrusatol,鸦胆子素 A,NSC31616
Target: Antibiotic, Parasite
FR-198248
Cat.No: T27380
Synonym:
Target: Others
Liriodenine
Cat.No: TN1875
Synonym: 鹅掌揪碱
Target: BCL, Caspase, p53
Cat. No. Product Name Species Expression System
TMPY-02789 IL-33 Protein, Canine, Recombinant

白介素,interleukin 33,白细胞介素

Canine E. coli
IL-33 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.8 kDa and the accession number is O97863.
TMPY-04342 PD-1 Protein, Canine, Recombinant (His)

programmed cell death 1

Canine HEK293 Cells
PD-1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is XP_022265285.1.
TMPY-00237 PD-L1 Protein, Canine, Recombinant (hFc)

CD274 molecule

Canine HEK293 Cells
PD-L1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.5 kDa and the accession number is A0A8C0MRV9.
TMPY-03719 HER2/ERBB2 Protein, Canine, Recombinant (His)

erb-b2 receptor tyrosine kinase 2,EGFR2

Canine HEK293 Cells
HER2/ERBB2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.4 kDa and the accession number is A8WED5.
TMPY-05815 PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated

programmed cell death 1

Canine HEK293 Cells
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 19.41 kDa and the accession number is A0A090BAM7.
TMPY-00616 CD3 epsilon/CD3e Protein, Canine, Recombinant (hFc)

CD3e molecule, ε (CD3-TCR complex),CD3 ε/CD3e,CD3e molecule,...

Canine HEK293 Cells
CD3 epsilon/CD3e Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.2 kDa and the accession number is P27597.
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

transforming growth factor, beta 1,转化生长因子,transforming growt...

Human,Rhesus,Cynomolgus,Canine CHO Cells
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession number is A0A499FJK2.
TMPY-02568 IL-1 beta/IL-1F2 Protein, Canine, Recombinant

interleukin 1, beta,IL-1 β,interleukin 1, β

Canine E. coli
IL-1 beta/IL-1F2 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.6 kDa and the accession number is Q28292.
TMPY-00680 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

bone morphogenetic protein 2

Human,Mouse,Rat,Rhesus,Canine HEK293 Cells
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.
TMPY-00456 HGF Protein, Canine, Recombinant

肝细胞生长因子,scatter factor),hepatocyte growth factor (hepapoieti...

Canine HEK293 Cells
HGF Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.9 kDa and the accession number is Q867B7.
TMPY-04884 EGF Protein, Canine, Recombinant

epidermal growth factor,表皮生长因子

Canine P. pastoris (Yeast)
EGF Protein, Canine, Recombinant is expressed in yeast. The predicted molecular weight is 6.2 kDa and the accession number is Q9BEA0.
TMPY-03898 Fractalkine Protein, Canine, Recombinant

chemokine (C-X3-C motif) ligand 1

Canine HEK293 Cells
Fractalkine Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.2 kDa and the accession number is H1ADY9.
TMPY-03944 CD40 Protein, Canine, Recombinant

CD40 molecule, TNF receptor superfamily member 5

Canine HEK293 Cells
CD40 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.9 kDa and the accession number is Q7YRL5.
TMPY-03711 TrkA Protein, Canine, Recombinant (hFc)

neurotrophic tyrosine kinase, receptor, type 1

Canine HEK293 Cells
TrkA Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.3 kDa and the accession number is XP_851619.3.
TMPY-02539 EGF Protein, Canine, Recombinant (His)

epidermal growth factor,表皮生长因子

Canine E. coli
EGF Protein, Canine, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 8.3 kDa and the accession number is Q9BEA0.
TMPY-00455 PDGFA Protein, Canine, Recombinant (hFc)

血小板源生长因子,platelet-derived growth factor α polypeptide,platel...

Canine HEK293 Cells
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDG...
TMPK-01385 CRTAM Protein, Canine, Recombinant (His)

CRTAM,CD355 antigen,CD355

Canine HEK293 Cells
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Pr...
TMPY-01594 TNF alpha Protein, Canine, Recombinant

肿瘤坏死因子,TNF-α,tumor necrosis factor

Canine E. coli
TNF alpha Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A9LMQ0.
TMPY-03724 EGFR Protein, Canine, Recombinant (His)

epidermal growth factor receptor

Canine Baculovirus Insect Cells
EGFR Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is XP_533073.3.
TMPY-03635 TrkB Protein, Canine, Recombinant (His)

neurotrophic tyrosine kinase, receptor, type 2

Canine HEK293 Cells
TrkB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is XP_541264.2.
TMPK-01375 PRLR Protein, Canine, Recombinant (hFc)

PRL-R,Prolactin R,MFAB,HPRL

Canine HEK293 Cells
Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers. PRLR Protein, Canine, Recombinant (hFc) is expressed in HEK293 ...
TMPY-03705 VEGF164 Protein, Canine, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Canine HEK293 Cells
VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3.
TMPH-00498 Prorelaxin Protein, Canine, Recombinant (His)

RLN,Prorelaxin

Canine E. coli
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. Prorelaxin Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.6 kDa and the accession number is Q9TRM8.
TMPH-00487 EPOR Protein, Canine, Recombinant (His)

EPOR,Erythropoietin receptor

Canine E. coli
EPOR Protein, Canine, Recombinant (His) is expressed in E. coli.
TMPY-00228 TrkB Protein, Canine, Recombinant (hFc)

neurotrophic tyrosine kinase, receptor, type 2

Canine HEK293 Cells
TrkB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is XP_541264.2.
TMPK-01257 DDT Proten, Canine, Recombinant (His)

EC 4.1.1.84,DDCT,D-DT,MIF2

Canine E. coli
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. DDT Proten, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predict...
TMPY-03897 Fractalkine Protein, Canine, Recombinant (hFc)

chemokine (C-X3-C motif) ligand 1

Canine HEK293 Cells
Fractalkine Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.4 kDa and the accession number is H1ADY9.
TMPY-04535 GDNF Protein, Canine, Recombinant (hFc)

glial cell derived neurotrophic factor,胶质细胞生长因子

Canine HEK293 Cells
GDNF Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is XP_005619436.1.
TMPY-04665 Fractalkine Protein, Canine, Recombinant (His)

chemokine (C-X3-C motif) ligand 1

Canine HEK293 Cells
Fractalkine Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.9 kDa and the accession number is A0A8C0YVN8.
TMPY-03712 TrkA Protein, Canine, Recombinant (His)

neurotrophic tyrosine kinase, receptor, type 1

Canine HEK293 Cells
TrkA Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is XP_851619.3.
TMPY-05076 PDGFB Protein, Canine, Recombinant (His)

platelet-derived growth factor beta polypeptide,platelet-der...

Canine P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicte...
TMPK-01097 AFP Protein, Canine, Recombinant (His)

Alpha-fetoprotein,HPAFP,Alpha-1-fetoprotein,α-1-fetoprotein,...

Canine HEK293 Cells
Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases. AFP Protei...
TMPY-05075 PDGFA Protein, Canine, Recombinant (His)

platelet-derived growth factor α polypeptide,血小板源生长因子,platel...

Canine P. pastoris (Yeast)
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDG...
TMPY-03622 FGF-1 Protein, Canine, Recombinant

fibroblast growth factor 1 (acidic)

Canine E. coli
FGF-1 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is A0A8C0QGP1.
TMPY-02809 IL-21 Protein, Canine, Recombinant

interleukin 21,白细胞介素,白介素

Canine E. coli
IL-21 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q6L7I9.
TMPY-02790 IL-4 Protein, Canine, Recombinant

白介素,interleukin 4,白细胞介素

Canine E. coli
IL-4 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is O77762.
TMPY-04033 FGF-14 Protein, Canine, Recombinant

fibroblast growth factor 14

Canine E. coli
FGF-14 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.1 kDa and the accession number is XP_003363267.1.
TMPK-00571 OSMR Protein, Canine, Recombinant (His)

OSMRB,IL-31R-β,OSMR,OSMRBMGC150626,OSMR β,IL-31R subunit β,I...

Canine HEK293 Cells
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death. OSMR Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted mole...
TMPY-03896 CXCL16 Protein, Canine, Recombinant (hFc)

chemokine (C-X-C motif) ligand 16

Canine HEK293 Cells
CXCL16 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.1 kDa and the accession number is XP_849304.2.
TMPY-02834 RBP4 Protein, Canine, Recombinant (hFc)

retinol binding protein 4, plasma

Canine HEK293 Cells
RBP4 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is F1PQI4.
TMPY-00626 CD2 Protein, Canine, Recombinant (hFc)

CD2 molecule

Canine HEK293 Cells
CD2 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.6 kDa and the accession number is A0A8C0SEN8.
TMPY-04086 CD40 Ligand Protein, Canine, Recombinant

CD40 ligand

Canine HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16 kDa and the accession number is O97626.
TMPY-03907 CD40 Protein, Canine, Recombinant (hFc)

CD40 molecule, TNF receptor superfamily member 5

Canine HEK293 Cells
CD40 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.1 kDa and the accession number is Q7YRL5.
TMPY-04084 ANGPTL1 Protein, Canine, Recombinant (hFc)

angiopoietin-like 1

Canine HEK293 Cells
Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an important role in the pathogenesis of hepatocellular carcinoma (HCC).The downregulation of the angiopoietin-like protein ANGPTL1 is associated with vascular invasion, tumor thrombus, metastasis, and poor prognosis in HCC. Ectopic expression of ANGPTL1 in HCC cells effectively decre...
TMPK-01387 EPhA3 Protein, Canine, Recombinant (His)

HEK4,TYRO4,ETK1,EPHA3,HEK,ETK,EK4

Canine HEK293 Cells
Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (‑295~‑261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.
TMPY-03906 IL-17 Protein, Canine, Recombinant

白细胞介素,interleukin 17A,白介素

Canine E. coli
IL-17 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is C6L8D7.
TMPY-03517 FGF-12 Protein, Canine, Recombinant

fibroblast growth factor 12

Canine E. coli
FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. ...
TMPH-00486 Chymase Protein, Canine, Recombinant (His & SUMO)

Chymase,Alpha-chymase,CMA1,Mast cell protease I

Canine E. coli
Chymase Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-04089 CD40 Protein, Canine, Recombinant (His)

CD40 molecule, TNF receptor superfamily member 5

Canine HEK293 Cells
CD40 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q7YRL5.
TMPY-02417 FOLR1 Protein, Canine, Recombinant (hFc)

folate receptor 1 (adult)

Canine HEK293 Cells
FOLR1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.7 kDa and the accession number is A0A8C0Z2T7.
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重组蛋白

IL-33 Protein, Canine, Recombinant
Cat.No: TMPY-02789
Species: Canine
Expression System: E. coli
PD-1 Protein, Canine, Recombinant (His)
Cat.No: TMPY-04342
Species: Canine
Expression System: HEK293 Cells
PD-L1 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00237
Species: Canine
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Canine, Recombinant (His)
Cat.No: TMPY-03719
Species: Canine
Expression System: HEK293 Cells
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05815
Species: Canine
Expression System: HEK293 Cells
CD3 epsilon/CD3e Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00616
Species: Canine
Expression System: HEK293 Cells
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
Cat.No: TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO Cells
IL-1 beta/IL-1F2 Protein, Canine, Recombinant
Cat.No: TMPY-02568
Species: Canine
Expression System: E. coli
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)
Cat.No: TMPY-00680
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: HEK293 Cells
HGF Protein, Canine, Recombinant
Cat.No: TMPY-00456
Species: Canine
Expression System: HEK293 Cells
EGF Protein, Canine, Recombinant
Cat.No: TMPY-04884
Species: Canine
Expression System: P. pastoris (Yeast)
Fractalkine Protein, Canine, Recombinant
Cat.No: TMPY-03898
Species: Canine
Expression System: HEK293 Cells
CD40 Protein, Canine, Recombinant
Cat.No: TMPY-03944
Species: Canine
Expression System: HEK293 Cells
TrkA Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-03711
Species: Canine
Expression System: HEK293 Cells
EGF Protein, Canine, Recombinant (His)
Cat.No: TMPY-02539
Species: Canine
Expression System: E. coli
PDGFA Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00455
Species: Canine
Expression System: HEK293 Cells
CRTAM Protein, Canine, Recombinant (His)
Cat.No: TMPK-01385
Species: Canine
Expression System: HEK293 Cells
TNF alpha Protein, Canine, Recombinant
Cat.No: TMPY-01594
Species: Canine
Expression System: E. coli
EGFR Protein, Canine, Recombinant (His)
Cat.No: TMPY-03724
Species: Canine
Expression System: Baculovirus Insect Cells
TrkB Protein, Canine, Recombinant (His)
Cat.No: TMPY-03635
Species: Canine
Expression System: HEK293 Cells
PRLR Protein, Canine, Recombinant (hFc)
Cat.No: TMPK-01375
Species: Canine
Expression System: HEK293 Cells
VEGF164 Protein, Canine, Recombinant
Cat.No: TMPY-03705
Species: Canine
Expression System: HEK293 Cells
Prorelaxin Protein, Canine, Recombinant (His)
Cat.No: TMPH-00498
Species: Canine
Expression System: E. coli
EPOR Protein, Canine, Recombinant (His)
Cat.No: TMPH-00487
Species: Canine
Expression System: E. coli
TrkB Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00228
Species: Canine
Expression System: HEK293 Cells
DDT Proten, Canine, Recombinant (His)
Cat.No: TMPK-01257
Species: Canine
Expression System: E. coli
Fractalkine Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-03897
Species: Canine
Expression System: HEK293 Cells
GDNF Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-04535
Species: Canine
Expression System: HEK293 Cells
Fractalkine Protein, Canine, Recombinant (His)
Cat.No: TMPY-04665
Species: Canine
Expression System: HEK293 Cells
TrkA Protein, Canine, Recombinant (His)
Cat.No: TMPY-03712
Species: Canine
Expression System: HEK293 Cells
PDGFB Protein, Canine, Recombinant (His)
Cat.No: TMPY-05076
Species: Canine
Expression System: P. pastoris (Yeast)
AFP Protein, Canine, Recombinant (His)
Cat.No: TMPK-01097
Species: Canine
Expression System: HEK293 Cells
PDGFA Protein, Canine, Recombinant (His)
Cat.No: TMPY-05075
Species: Canine
Expression System: P. pastoris (Yeast)
FGF-1 Protein, Canine, Recombinant
Cat.No: TMPY-03622
Species: Canine
Expression System: E. coli
IL-21 Protein, Canine, Recombinant
Cat.No: TMPY-02809
Species: Canine
Expression System: E. coli
IL-4 Protein, Canine, Recombinant
Cat.No: TMPY-02790
Species: Canine
Expression System: E. coli
FGF-14 Protein, Canine, Recombinant
Cat.No: TMPY-04033
Species: Canine
Expression System: E. coli
OSMR Protein, Canine, Recombinant (His)
Cat.No: TMPK-00571
Species: Canine
Expression System: HEK293 Cells
CXCL16 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-03896
Species: Canine
Expression System: HEK293 Cells
RBP4 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-02834
Species: Canine
Expression System: HEK293 Cells
CD2 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00626
Species: Canine
Expression System: HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant
Cat.No: TMPY-04086
Species: Canine
Expression System: HEK293 Cells
CD40 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-03907
Species: Canine
Expression System: HEK293 Cells
ANGPTL1 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-04084
Species: Canine
Expression System: HEK293 Cells
EPhA3 Protein, Canine, Recombinant (His)
Cat.No: TMPK-01387
Species: Canine
Expression System: HEK293 Cells
IL-17 Protein, Canine, Recombinant
Cat.No: TMPY-03906
Species: Canine
Expression System: E. coli
FGF-12 Protein, Canine, Recombinant
Cat.No: TMPY-03517
Species: Canine
Expression System: E. coli
Chymase Protein, Canine, Recombinant (His & SUMO)
Cat.No: TMPH-00486
Species: Canine
Expression System: E. coli
CD40 Protein, Canine, Recombinant (His)
Cat.No: TMPY-04089
Species: Canine
Expression System: HEK293 Cells
FOLR1 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-02417
Species: Canine
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMIH-0209 Elobixibat-d5

Elobixibat-d5 是 Elobixibat 的氘代化合物。Elobixibat 的 CAS 号为 439087-18-0。Elobixibat 是回肠胆汁酸转运蛋白的抑制剂(小鼠、人和犬 IBAT 的 IC50:0.13 nM、0.53 nM 和 5.8 nM)。 Elobixibat 可用于慢性特发性便秘的研究。
TMIH-0301 Levolansoprazole-d4

Levolansoprazole-d4 是 Levolansoprazole 的氘代化合物。Levolansoprazole 的 CAS 号为 138530-95-7。Levolansoprazole 是一种质子泵抑制剂,不可逆地抑制壁细胞中 H+/K+ 刺激的 ATPase 泵 (IC50: 5.2 µM)。它还抑制分离的犬壁细胞中的酸形成(IC50:82 µM)。 (R)-和 (S)-兰索拉唑均具有药理活性,具有相似的效力。
T71143 Ambroxol-d5

Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part...
T69995 Chlorhexidine-d8 HCl

Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 μg/ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC...

同位素标记化合物

Elobixibat-d5
Cat.No: TMIH-0209
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Levolansoprazole-d4
Cat.No: TMIH-0301
Synonym:
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Ambroxol-d5
Cat.No: T71143
Synonym:
Target:
Chlorhexidine-d8 HCl
Cat.No: T69995
Synonym:
Target:
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