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Search Results for " repeat "

Targets Recommended: Histone Methyltransferase JAK

65

抑制剂 & 化合物

103

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T3201	WDR5-0103 WD-Repeat Protein 5-0103	Histone Methyltransferase; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	WDR5-0103 (WD-Repeat Protein 5-0103) 是一种有效且特异性的 WD 重复蛋白 5 (WDR5) 拮抗剂，Kd 值为450 nM。
T40409	Tau Peptide (275-305) (Repeat 2 domain)
	Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining the biochemical characteristics of the complete tau protein.
T5140	WDR5-0103 hydrochloride[890190-22-4(free base)] WD-Repeat Protein 5-0103,WDR5-0103盐酸盐	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) 是一种有效且特异性的 WD 重复蛋白 5 (WDR5) 拮抗剂 (Kd: 450 nM)。
TP2292	survivin (baculoviral IAP repeat-containing protein 5) (21-28)	Others	Others
	Survivin (baculoviral inhibitor of apoptosis IAP repeat-containing protein-5) is a member of the IAP gene family, which has been implicated in both inhibitions of apoptosis and mitosis regulation1. Survivin is one of the most uniformly up-regulated genes
T1945	GNE-7915 GNE7915	LRRK2	Autophagy
	GNE-7915是一种高效选择性，可渗透大脑的，富含亮氨酸的重复激酶 2 (LRRK2) 抑制剂，IC50值为9 nM。
T39972	EB-42486	LRRK2	Autophagy
	EB-42486 是一种有效且高度选择性的 G2019S-LRRK2 抑制剂，IC50 < 0.2 nM。
T16115	MLi-2	LRRK2	Autophagy
	MLi-2 是一种结构新颖、高效、选择性的 LRRK2 激酶抑制剂，具有中枢神经系统活性，IC50为 0.76 nM，有潜力用于帕金森氏病。
T2050	PF-06447475	LRRK2	Autophagy
	PF-06447475是一种高效、特异性的脑渗透性 LRRK2 抑制剂，IC50值为3 nM。
T7729	PF-06454589	LRRK2	Autophagy
	PF-06447475 是LRRK2激酶选择性抑制剂，可通透血脑屏障，能够抑制 WT LRRK (IC50:3 nM) 和 G2019S LRRK2 (IC50:11 nM) 。它可用于研究帕金森病 (PD) 。
T8956	BC-1258 BC-1258	Apoptosis	Apoptosis
	BC-1258 是一种 F-box/LRR-重复蛋白 2激活剂，可诱导致瘤细胞凋亡，并显著抑制小鼠的肿瘤形成，还可以稳定和上调 FBXL2 水平。
T2022	CZC-54252 CZC54252,CZC 54252	LRRK2	Autophagy
	CZC-54252 是一种选择性 LRRK2有效抑制剂，对野生型和 G2019S LRRK2的 IC50分别为 1.28 nM 和 1.85 nM。它具有神经保护活性，可减弱由 G2019S LRRK2 诱导的人神经元损伤，EC50约为 1 nM。
T8985	NSC45586	Others	Others
	NSC45586 是一种蛋白磷酸酶 PHLPP 抑制剂，对 PHLPP1 和 PHLPP2 具有选择性。
T1770	GNE-9605	LRRK2	Autophagy
	GNE-9605 是一个高效，选择性和能脑渗透的LRRK2抑制剂，IC50为19 nM。
T7155	JH-II-127	LRRK2	Autophagy
	JH-II-127是一种高选择性的脑渗透性 LRRK2 抑制剂，抑制野生型 LRRK2、G2019S LRRK2和 A2016T LRRK2，IC50 值分别为6.6 nM、2.2 nM 和 47.7 nM。
T16512	PFE-360 PF-06685360	LRRK2	Autophagy
	PFE-360 (PF-06685360) 是一种有效的选择性 LRRK2 激酶抑制剂，在体内的 IC50值为 2.3 nM。
T39202	CZC-54252 hydrochloride	LRRK2	Autophagy
	CZC-54252 hydrochloride 是 LRRK2 的特异性抑制剂，对野生型和 G2019S LRRK2 的 IC50 分别为 1.85 nM 和 1.28 nM。 CZC-54252 hydrochloride 具有神经保护活性，可减轻 G2019S LRRK2 诱导的人类神经元损伤，EC50 为 1 nM。
T6031	GNE0877 GNE 0877,GNE-0877	LRRK2	Autophagy
	GNE0877 (GNE 0877) 是一种高效且特异性的富含亮氨酸的重复激酶 2(LRRK2) 抑制剂，IC50为3 nM，Ki 为0.7 nM
T6916	OICR-9429 OICR 9429	Histone Methyltransferase; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	OICR-9429 是一个新颖的相互作用的小分子Wdr5-MLL 拮抗剂，IC50是 5 uM，在体外抑制急性髓性白血病细胞。
T3053	CZC-25146 CHEMBL2397014	LRRK2	Autophagy
	CZC-25146 (CHEMBL2397014) 是一种有效、特异性和代谢稳定的 LRRK2 抑制剂，对野生型 LRRK2 和 G2019S LRRK2 的 IC50 分别为 4.76 和 6.87 nM。
T5139	CZC-25146 hydrochloride	LRRK2	Autophagy
	CZC-25146 hydrochloride 是一种有效、特异性和代谢稳定的 LRRK2 抑制剂，对野生型 LRRK2 和 G2019S LRRK2 的 IC50 分别为 4.76 和 6.87 nM。
T6176	IKK 16 IKK Inhibitor VII,IKK-16,IKK16	IκB/IKK; LRRK2	Autophagy; NF-κB
	IKK 16 (IKK Inhibitor VII) 是一种选择性的 IκB 激酶 (IKK) 抑制剂，作用于 IKK2、IKK complex 和 IKK1，IC50分别为 40 nM、70 nM 和 200 nM。它还抑制富亮氨酸重复激酶 2，IC50为 50 nM。
T2240	GSK2578215A 5-(2-氟-4-吡啶基)-2-(苯基甲氧基)-N-3-吡啶基苯甲酰胺	Mitophagy; LRRK2; Autophagy	Autophagy
	GSK2578215A 是一种有效的选择性 LRRK2 激酶抑制剂，对野生型 LRRK2 和 G2019S 突变型的IC50值都约为 10 nM。
T2246	LRRK2-IN-1 5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1,4]苯并二氮杂卓-6-酮	Apoptosis; LRRK2; CDK	Apoptosis; Autophagy; Cell Cycle/Checkpoint
	LRRK2-IN-1 是一种选择性的LRRK2有效抑制剂，作用于 LRRK2 (G2019S) 和 LRRK2 (WT)，IC50值分别为 6 nM 和 13 nM。
T7196	HG-10-102-01 [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮	LRRK2	Autophagy
	HG-10-102-01 是富含亮氨酸重复激酶 2 和突变型G2019S 抑制剂，IC50分别为20.3 nM 和3.2 nM。
T9236	WSB1 Degrader 1	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	WSB1 Degrader 1 是具有口服活性的 WSB1降解剂，具有抗癌活性。
T9632	CDK9-IN-30	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	CDK9-IN-30 是 Tat 肽衍生物之一，可抑制 HIV-1 长末端重复激活转录。
T27029	cjoc42 cjoc 42,cjoc-42	Others	Others
	Cjoc42 是gankyrin 的抑制剂，以剂量依赖性方式抑制 gankyrin 活性。它可防止 p53 蛋白水平的降低。它恢复 p53 依赖性转录和对 DNA 损伤的敏感性。
TP1120L	IRBP acetate(211426-18-5 free base) Interphotoreceptor Retinoid Binding Protein Fragment IRBP	Others	Others
	IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) 是一种含有 20 个残基的肽，是一种主要的致病表位。它存在于间质视觉色素结合蛋白肽（IRBP 161-180）的第一个同源重复序列中，可诱导葡萄膜炎后（EAU）。
T8768	MM-102 TFA HMTase Inhibitor IX TFA	Histone Methyltransferase	Chromatin/Epigenetic
	MM-102 TFA (HMTase Inhibitor IX TFA) 是一种有效的 WDR5/MLL 相互作用抑制剂，在 WDR5 结合检测中，IC50为 2.4 nM，Ki 小于 1 nM。
T22021	ACHP IKK-2 Inhibitor VIII	IκB/IKK	NF-κB
	ACHP(IKK-2 Inhibitor VIII) 是一种新型具有选择性和高效性的 IKK 抑制剂，对IKK-α和IKK-β 具有抑制作用。ACHP 具有抗 HIV-1 活性，通过抑制 NF-κB 激活来抑制 HIV-1 长末端重复序列（LTR）驱动的基因表达，抑制 TNF-α 诱导的 NF-κB （p65）募集到 HIV-1 LTR。
TP1616L	Hsp70-derived octapeptide acetate Hsp70-derived octapeptide acetate(736171-62-3 free base)	Others	Others
	Hsp70-derived octapeptide acetate (Hsp70-derived octapeptide acetate)(736171-62-3 free base) 是一组含有四肽重复 (TPR) 的蛋白质，已显示与 70 kDa 热休克同源蛋白 (hsc70) 的 C 末端结构域相互作用。在本研究中，含 TPR 的蛋白质，包括 hsc70 相互作用蛋白 (CHIP)、TPR1 和人富含谷氨酰胺的 TPR 含蛋白 (hSGT) 的 C 端，对 DnaJ 和 hsc70 对荧光素酶重折叠的影响进行了调查。
T13334	WDR5-IN-1	Others	Others
	WDR5-IN-1 is a potent and selective inhibitor of WD repeat domain 5 (WDR5) (Kd <0.02 nM), and also inhibits MLL1 histone methyltransferase (HMT) activity (IC50: 2.2 nM).
T12091	MM-589	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.
T74889	XF067-68	Others	Others
	XF067-68 是一种靶向降解 WD40 重复域蛋白5 (WDR5) 的 PROTAC。
T12091L	MM-589 TFA	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.
T13342	WDR5-IN-4 WIN site inhibitor 1	Others	Others
	WIN site inhibitor 1 is a WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5) inhibitor (Kd: 0.1 nM), with anti-cancer activity.
T79351	JH-XII-03-02	PROTACs	PROTAC
	JH-XII-03-02为高效的选择性LRRK2 PROTAC降解剂，适用于帕金森病相关研究。
T39978	Dimethyl-F-OICR-9429-COOH	Others	Others
	Dimethyl-F-OICR-9429-COOH, a ligand for WD40 repeat domain protein 5 (WDR5). This compound is utilized as a key component in the synthesis of PROTACs.
T15557	IKK 16 hydrochloride	Others	Others
	IKK 16 hydrochloride is a selective IKK2, IKK complex, and IKK1 IκB kinase (IKK) inhibitor (IC50s: 40 nM, 70 nM and 200 nM, respectively). IKK16 inhibits leucine-rich repeat kinase-2 (LRRK2; IC50: 50 nM).
T70363	PF-06371900	Others	Others
	PF-06371900 是一种有效的高选择性富亮氨酸重复激酶2 (LRRK2) 抑制剂。
T74888	XF056-132	Others	Others
	XF056-132 是一种有效的WDR5(WD40 重复结构域蛋白 5)PROTAC 降解剂。
T13342L	WIN site inhibitor 1 TFA (2407457-36-5 free base) WIN site inhibitor 1 TFA	Others	Others
	WIN site inhibitor 1 TFA is a WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5) inhibitor (Kd: 0.1 nM).
T39976	MS67	PROTACs	PROTAC
	MS67 is a potent and selective degrader of the WD40 repeat domain protein 5 (WDR5) with a dissociation constant (Kd) of 63 nM. It exhibits no activity against protein methyltransferases, kinases, G-protein-coupled receptors (GPCRs), ion channels, and transporters. Notably, MS67 demonstrates significant anticancer properties.
T82560	di-Ellipticine-RIBOTAC	PROTACs	PROTAC
	Di-Ellipticine-RIBOTAC是一款双功能小分子，在体外和体内肌萎缩侧索硬化（ALS）模型中能够减少c9ALS/FTD r(G4C2)的重复扩增。
T76652	PHF6
	PHF6 (VQIVYK) 为一自组装序列，能启动全长tau蛋白聚集，其定位于tau蛋白第三个微管结合重复区。
TP1120	Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP
	Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (IRBP 161-180) and can induce post-uv
T72999	PF-06455943	Others	Others
	PF-06455943, 作为一种LRRK2 (富含亮氨酸的重复激酶 2) 抑制剂，具有3 nM的IC50值，主要用于帕金森病（PD）的研究。
T68364	GS-9160	Others	Others
	GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer. It is an authentic inhibitor of HIV-1 integration, since treatment of infected cells results in an elevation of two-long terminal repeat circles and a decrease of integration junctions.
T62863	FLT3/ITD-IN-4	Others	Others
	FLT3/ITD-IN-4 (Compound 16) 是一种选择性的 FLT3 内部串联重复突变 (FLT3-ITD) 抑制剂 (IC50: 2.3 nM)。FLT3/ITD-IN-4 能够用于研究急性骨髓性白血病。
T73885	Methyl gerfelin	Others	Others
	Methyl gerfelin通过与三种关键细胞蛋白乙二醛酶 1 (GLO1)、固醇结合蛋白 2 (SCP2) 和富含谷氨酰胺的四肽重复蛋白 A (SGTA) 结合，抑制破骨细胞的分化。研究表明，Methyl gerfelin是一种与类黄酮相关的强效GLO1抑制剂。

化合物

Cat.No: T3201

Synonym: WD-Repeat Protein 5-0103

Target: Histone Methyltransferase, JAK

Tau Peptide (275-305) (Repeat 2 domain)

Cat.No: T40409

WDR5-0103 hydrochloride[890190-22-4(free base)]

Cat.No: T5140

Synonym: WD-Repeat Protein 5-0103,WDR5-0103盐酸盐

Target: JAK

survivin (baculoviral IAP repeat-containing protein 5) (21-28)

Cat.No: TP2292

Target: Others

Cat.No: T1945

Synonym: GNE7915

Target: LRRK2

Cat.No: T39972

Target: LRRK2

Cat.No: T16115

Target: LRRK2

Cat.No: T2050

Target: LRRK2

Cat.No: T7729

Target: LRRK2

Cat.No: T8956

Synonym: BC-1258

Target: Apoptosis

Cat.No: T2022

Synonym: CZC54252,CZC 54252

Target: LRRK2

Cat.No: T8985

Target: Others

Cat.No: T1770

Target: LRRK2

Cat.No: T7155

Target: LRRK2

Cat.No: T16512

Synonym: PF-06685360

Target: LRRK2

CZC-54252 hydrochloride

Cat.No: T39202

Target: LRRK2

Cat.No: T6031

Synonym: GNE 0877,GNE-0877

Target: LRRK2

Cat.No: T6916

Synonym: OICR 9429

Target: Histone Methyltransferase, JAK

Cat.No: T3053

Synonym: CHEMBL2397014

Target: LRRK2

CZC-25146 hydrochloride

Cat.No: T5139

Target: LRRK2

Cat.No: T6176

Synonym: IKK Inhibitor VII,IKK-16,IKK16

Target: IκB/IKK, LRRK2

Cat.No: T2240

Synonym: 5-(2-氟-4-吡啶基)-2-(苯基甲氧基)-N-3-吡啶基苯甲酰胺

Target: Mitophagy, LRRK2, Autophagy

Cat.No: T2246

Synonym: 5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1,4]苯并二氮杂卓-6-酮

Target: Apoptosis, LRRK2, CDK

Cat.No: T7196

Synonym: [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮

Target: LRRK2

WSB1 Degrader 1

Cat.No: T9236

Target: Others, E1/E2/E3 Enzyme

Cat.No: T9632

Target: HIV Protease

Cat.No: T27029

Synonym: cjoc 42,cjoc-42

Target: Others

IRBP acetate(211426-18-5 free base)

Cat.No: TP1120L

Synonym: Interphotoreceptor Retinoid Binding Protein Fragment IRBP

Target: Others

Cat.No: T8768

Synonym: HMTase Inhibitor IX TFA

Target: Histone Methyltransferase

Cat.No: T22021

Synonym: IKK-2 Inhibitor VIII

Target: IκB/IKK

Hsp70-derived octapeptide acetate

Cat.No: TP1616L

Synonym: Hsp70-derived octapeptide acetate(736171-62-3 free base)

Target: Others

Cat.No: T13334

Target: Others

Cat.No: T12091

Target: JAK

Cat.No: T74889

Target: Others

Cat.No: T12091L

Target: JAK

Cat.No: T13342

Synonym: WIN site inhibitor 1

Target: Others

Cat.No: T79351

Target: PROTACs

Dimethyl-F-OICR-9429-COOH

Cat.No: T39978

Target: Others

IKK 16 hydrochloride

Cat.No: T15557

Target: Others

Cat.No: T70363

Target: Others

Cat.No: T74888

Target: Others

WIN site inhibitor 1 TFA (2407457-36-5 free base)

Cat.No: T13342L

Synonym: WIN site inhibitor 1 TFA

Target: Others

Cat.No: T39976

Target: PROTACs

di-Ellipticine-RIBOTAC

Cat.No: T82560

Target: PROTACs

Cat.No: T76652

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)

Cat.No: TP1120

Synonym: IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP

Cat.No: T72999

Target: Others

Cat.No: T68364

Target: Others

Cat.No: T62863

Target: Others

Methyl gerfelin

Cat.No: T73885

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc) leucine rich repeat containing 15,LIB	Human	HEK293 Cells
	LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-01395	CTHRC1 Protein, Human, Recombinant (His) collagen triple helix repeat containing 1	Human	HEK293 Cells
	CTHRC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.5 kDa and the accession number is Q96CG8-1.
TMPY-05085	LRRC32 Protein, Human, Recombinant (His) leucine rich repeat containing 32,GARP,D11S833E	Human	HEK293 Cells
	LRRC32 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7.
TMPY-06910	LRRC15 Protein, Cynomolgus, Recombinant (His) leucine rich repeat containing 15	Cynomolgus	HEK293 Cells
	LRRC15 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.28 kDa and the accession number is G7NYR2.
TMPY-04856	LRRTM2 Protein, Human, Recombinant (hFc) leucine rich repeat transmembrane neuronal 2	Human	HEK293 Cells
	LRRTM2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is O43300.
TMPY-04288	CTHRC1 Protein, Rat, Recombinant (His) collagen triple helix repeat containing 1	Rat	HEK293 Cells
	CTHRC1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is NP_001258229.1.
TMPY-06826	CTHRC1 Protein, Human, Recombinant (His & Avi), Biotinylated collagen triple helix repeat containing 1	Human	HEK293 Cells
	CTHRC1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.33 kDa and the accession number is NP_612464.1.
TMPY-04823	LRRTM2 Protein, Human, Recombinant (His) leucine rich repeat transmembrane neuronal 2	Human	HEK293 Cells
	LRRTM2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is O43300.
TMPY-06148	LRRC15 Protein, Human, Recombinant (His) leucine rich repeat containing 15,LIB	Human	HEK293 Cells
	LRRC15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is Q8TF66-1.
TMPY-00088	LRRC3B Protein, Human, Recombinant (His) leucine rich repeat containing 3B,LRP15	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is A1LNH5.
TMPY-06795	CTHRC1 Protein, Mouse, Recombinant (His) 1110014B07Rik,collagen triple helix repeat containi...	Mouse	HEK293 Cells
	CTHRC1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.53 kDa and the accession number is Q9D1D6.
TMPY-05375	LRRC32 Protein, Human, Recombinant (His), Biotinylated leucine rich repeat containing 32,D11S833E,GARP	Human	HEK293 Cells
	LRRC32 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7.
TMPJ-00338	LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated Leucine-rich repeat-containing protein 15,LIB,LRRC1...	Human	HEK293 Cells
	The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal t...
TMPY-01655	LRRTM4 Protein, Human, Recombinant (His) leucine rich repeat transmembrane neuronal 4	Human	HEK293 Cells
	LRRTM4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q86VH4-1.
TMPY-06775	CTHRC1 Protein, Human, Recombinant (hFc) collagen triple helix repeat containing 1	Human	HEK293 Cells
	CTHRC1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.8 kDa and the accession number is NP_612464.1.
TMPY-06919	LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated LIB,leucine rich repeat containing 15,5430427N11Rik	Mouse	HEK293 Cells
	LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 60.74 kDa and the accession number is NP_083249.1.
TMPH-02753	LINGO1 Protein, Mouse, Recombinant (His) Leucine-rich repeat neuronal protein 6A,Leucine-ric...	Mouse	E. coli
	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. LINGO1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pre...
TMPH-02922	SRPX2 Protein, Mouse, Recombinant (His & Myc) Sushi repeat-containing protein SRPX2,Srpx2	Mouse	Baculovirus Insect Cells
	Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. Required for ultrasonic vocalizations. SRPX2 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N...
TMPH-01610	LINGO1 Protein, Human, Recombinant (His) Leucine-rich repeat neuronal protein 6A,LINGO1,Leuc...	Human	E. coli
	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.
TMPY-00353	LRRC3B Protein, Human, Recombinant (hFc) LRP15,leucine rich repeat containing 3B	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is A1LNH5.
TMPH-02923	SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO) Srpx2,Sushi repeat-containing protein SRPX2	Mouse	E. coli
	Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. Required for ultrasonic vocalizations. SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression syste...
TMPY-05803	NGL-1/LRRC4C Protein, Human, Recombinant (His) NGL-1,leucine rich repeat containing 4C,NGL1	Human	HEK293 Cells
	NGL-1/LRRC4C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.51 kDa and the accession number is Q9HCJ2.
TMPY-00068	LRRTM4 Protein, Mouse, Recombinant (His) leucine rich repeat transmembrane neuronal 4,A23005...	Mouse	HEK293 Cells
	LRRTM4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.4 kDa and the accession number is Q80XG9-2.
TMPY-05437	NGL-1/LRRC4C Protein, Mouse, Recombinant (His) NGL-1,leucine rich repeat containing 4C,6430556C10R...	Mouse	HEK293 Cells
	NGL-1/LRRC4C Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.5 kDa and the accession number is BAC27884.1.
TMPK-01030	LRRN1 Protein, Mouse, Recombinant (His) Neuronal leucine-rich repeat protein 1,LRN,NLRR1,NL...	Mouse	HEK293 Cells
	Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation.
TMPH-03073	TDX Protein, Japonica rice, Recombinant (His & Myc) OsTrx26,Tetratricoredoxin,TPR repeat-containing thi...	Rice	E. coli
	Probable thiol-disulfide oxidoreductase that may participate in various redox reactions and act as chaperone under heat shock. May interact with HSP70 proteins through the TPR repeats. TDX Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.0 kDa and the accession number is Q6ES52.
TMPJ-01407	FIS1 Protein, Human, Recombinant (His) FIS1 Homolog,FIS1,Tetratricopeptide Repeat Protein ...	Human	E. coli
	Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus i...
TMPH-01328	FBXL2 Protein, Human, Recombinant (His & SUMO) FBXL2,F-box and leucine-rich repeat protein 2,F-box...	Human	E. coli
	FBXL2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.1 kDa and the accession number is Q9UKC9.
TMPH-01205	DCAF7 Protein, Human, Recombinant (His) DDB1- and CUL4-associated factor 7,WDR68,DCAF7,WD repeat...	Human	E. coli
	Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
TMPH-01123	CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc) Collagen triple helix repeat-containing protein 1,C...	Human	HEK293 Cells
	May act as a negative regulator of collagen matrix deposition. CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc) is expressed in HEK293 mammalian cells with C-hFC tag. The predicted molecular weight is 52 kDa and the accession number is Q96CG8.
TMPH-02959	Tsukushi Protein, Mouse, Recombinant (His & Myc) Tsku,Leucine-rich repeat-containing protein 54,Tsuk...	Mouse	E. coli
	Tsukushi Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.0 kDa and the accession number is Q8CBR6.
TMPH-02593	CTHRC1 Protein, Mouse, Recombinant (His & SUMO) Collagen triple helix repeat-containing protein 1,C...	Mouse	E. coli
	May act as a negative regulator of collagen matrix deposition.
TMPJ-01249	ASB13 Protein, Human, Recombinant (His) ASB13,Ankyrin repeat and SOCS box protein 13	Human	E. coli
	Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex...
TMPH-02592	CTHRC1 Protein, Mouse, Recombinant (aa 33-245, His) Collagen triple helix repeat-containing protein 1,C...	Mouse	HEK293 Cells
	May act as a negative regulator of collagen matrix deposition.
TMPY-02491	LRRN3 Protein, Human, Recombinant (His) NLRR3,FIGLER5,leucine rich repeat neuronal 3,NLRR-3	Human	Baculovirus Insect Cells
	Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of the leucine-rich (LRR) family whose members have significant functions in neural development. Leucine-rich repeats are short sequence motifs present in some proteins with diverse functions and cellular locations. All proteins containing these repeats are thought to be involved in protein-protein interactions. The crystal structure of ribonuclease inhibitor protein has revealed th...
TMPH-03574	SdrE Protein, S. aureus, Recombinant (His) sdrE,Serine-aspartate repeat-containing protein E	Staphylococcus aureus	E. coli
	Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity. Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation. SdrE Protein, S. aureus, Recombin...
TMPY-06705	LRRC32 Protein, Mouse, Recombinant (His) Garp,AI426318,leucine rich repeat containing 32,D11...	Mouse	HEK293 Cells
	LRRC32 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.10 kDa and the accession number is G3XA59.
TMPY-06703	LRRC32 Protein, Mouse, Recombinant (hFc) leucine rich repeat containing 32,D11S833Eh,Garp,D7...	Mouse	HEK293 Cells
	LRRC32 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is G3XA59.
TMPY-04118	Livin/BIRC7 Protein, Human, Recombinant (His) MLIAP,baculoviral IAP repeat containing 7,RNF50,KIA...	Human	E. coli
	BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecu...
TMPH-01611	LGR6 Protein, Human, Recombinant (His) LGR6,Leucine-rich repeat-containing G-protein coupl...	Human	E. coli
	Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to t...
TMPY-03672	Survivin Protein, Human, Recombinant BIRC5,IAP4,API4,baculoviral IAP repeat containing 5...	Human	E. coli
	BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation...
TMPH-00101	PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) PDLP7,Cysteine-rich repeat secretory protein 60,Pla...	Arabidopsis thaliana	E. coli
	Modulates cell-to-cell trafficking. PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is Q0WPN8.
TMPY-00571	PRELP Protein, Human, Recombinant (mFc) proline/arginine-rich end leucine-rich repeat prote...	Human	HEK293 Cells
	PRELP Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 68.3 kDa and the accession number is P51888.
TMPH-00991	NAIP Protein, Human, Recombinant (His & SUMO) NAIP,Baculoviral IAP repeat-containing protein 1,Ne...	Human	E. coli
	NAIP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02311	WDR5 Protein, Human, Recombinant (His & SUMO) WDR5,BMP2-induced 3-kb gene protein,WD repeat-conta...	Human	E. coli
	WDR5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.5 kDa and the accession number is P61964.
TMPH-01426	HEATR6 Protein, Human, Recombinant (His & Myc) HEATR6,HEAT repeat-containing protein 6,Amplified i...	Human	E. coli
	HEATR6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-00572	PRELP Protein, Human, Recombinant proline/arginine-rich end leucine-rich repeat prote...	Human	HEK293 Cells
	PRELP Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 41.8 kDa and the accession number is P51888.
TMPY-01176	cIAP1 Protein, Human, Recombinant (Avi) Hiap-2,API1,HIAP2,RNF48,baculoviral IAP repeat cont...	Human	E. coli
	The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP repeats (BIRs). The BIR domains of cIAP1 and cIAP2 bind to caspases, the key effector proteases of apoptosis. The IAP protein family which can enhance cell survival are crucial regulators of programmed cell death. Both cIAP1 and cIAP2 are the E3 ubiquitin protein isopeptide ligase...
TMPH-01204	DCAF4 Protein, Human, Recombinant (His & SUMO) DCAF4,DDB1- and CUL4-associated factor 4,WDR21,WDR21A,WD	Human	E. coli
	May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
TMPJ-01227	Irisin Protein, Human/Mouse/Rat, Recombinant (C-His) FNDC5,Fibronectin type III repeat-containing protei...	Human,Mouse,Rat	HEK293 Cells
	Irisin Protein, Human/Mouse/Rat, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-28 KDa and the accession number is Q8NAU1.
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重组蛋白

LRRC15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04333

Species: Human

Expression System: HEK293 Cells

CTHRC1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01395

Species: Human

Expression System: HEK293 Cells

LRRC32 Protein, Human, Recombinant (His)

Cat.No: TMPY-05085

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-06910

Species: Cynomolgus

Expression System: HEK293 Cells

LRRTM2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04856

Species: Human

Expression System: HEK293 Cells

CTHRC1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-04288

Species: Rat

Expression System: HEK293 Cells

CTHRC1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06826

Species: Human

Expression System: HEK293 Cells

LRRTM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04823

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (His)

Cat.No: TMPY-06148

Species: Human

Expression System: HEK293 Cells

LRRC3B Protein, Human, Recombinant (His)

Cat.No: TMPY-00088

Species: Human

Expression System: HEK293 Cells

CTHRC1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06795

Species: Mouse

Expression System: HEK293 Cells

LRRC32 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05375

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00338

Species: Human

Expression System: HEK293 Cells

LRRTM4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01655

Species: Human

Expression System: HEK293 Cells

CTHRC1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06775

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06919

Species: Mouse

Expression System: HEK293 Cells

LINGO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02753

Species: Mouse

Expression System: E. coli

SRPX2 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02922

Species: Mouse

Expression System: Baculovirus Insect Cells

LINGO1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01610

Species: Human

Expression System: E. coli

LRRC3B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00353

Species: Human

Expression System: HEK293 Cells

SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-02923

Species: Mouse

Expression System: E. coli

NGL-1/LRRC4C Protein, Human, Recombinant (His)

Cat.No: TMPY-05803

Species: Human

Expression System: HEK293 Cells

LRRTM4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00068

Species: Mouse

Expression System: HEK293 Cells

NGL-1/LRRC4C Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05437

Species: Mouse

Expression System: HEK293 Cells

LRRN1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01030

Species: Mouse

Expression System: HEK293 Cells

TDX Protein, Japonica rice, Recombinant (His & Myc)

Cat.No: TMPH-03073

Species: Rice

Expression System: E. coli

FIS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01407

Species: Human

Expression System: E. coli

FBXL2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01328

Species: Human

Expression System: E. coli

DCAF7 Protein, Human, Recombinant (His)

Cat.No: TMPH-01205

Species: Human

Expression System: E. coli

CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc)

Cat.No: TMPH-01123

Species: Human

Expression System: HEK293 Cells

Tsukushi Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02959

Species: Mouse

Expression System: E. coli

CTHRC1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02593

Species: Mouse

Expression System: E. coli

ASB13 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01249

Species: Human

Expression System: E. coli

CTHRC1 Protein, Mouse, Recombinant (aa 33-245, His)

Cat.No: TMPH-02592

Species: Mouse

Expression System: HEK293 Cells

LRRN3 Protein, Human, Recombinant (His)

Cat.No: TMPY-02491

Species: Human

Expression System: Baculovirus Insect Cells

SdrE Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03574

Species: Staphylococcus aureus

Expression System: E. coli

LRRC32 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06705

Species: Mouse

Expression System: HEK293 Cells

LRRC32 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-06703

Species: Mouse

Expression System: HEK293 Cells

Livin/BIRC7 Protein, Human, Recombinant (His)

Cat.No: TMPY-04118

Species: Human

Expression System: E. coli

LGR6 Protein, Human, Recombinant (His)

Cat.No: TMPH-01611

Species: Human

Expression System: E. coli

Survivin Protein, Human, Recombinant

Cat.No: TMPY-03672

Species: Human

Expression System: E. coli

PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)

Cat.No: TMPH-00101

Species: Arabidopsis thaliana

Expression System: E. coli

PRELP Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00571

Species: Human

Expression System: HEK293 Cells

NAIP Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00991

Species: Human

Expression System: E. coli

WDR5 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02311

Species: Human

Expression System: E. coli

HEATR6 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01426

Species: Human

Expression System: E. coli

PRELP Protein, Human, Recombinant

Cat.No: TMPY-00572

Species: Human

Expression System: HEK293 Cells

cIAP1 Protein, Human, Recombinant (Avi)

Cat.No: TMPY-01176

Species: Human

Expression System: E. coli

DCAF4 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01204

Species: Human

Expression System: E. coli

Irisin Protein, Human/Mouse/Rat, Recombinant (C-His)

Cat.No: TMPJ-01227

Species: Human,Mouse,Rat

Expression System: HEK293 Cells

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