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Search Results for " bladder cancer "

Targets Recommended: c-Met/HGFR

32

抑制剂 & 化合物

8

天然产物

20

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0219	MK-8033	c-Met/HGFR	Tyrosine Kinase/Adaptors
	MK-8033 是一种新型ATP 竞争性c-Met/Ron 双重抑制剂，对野生型c-Met 的IC50=1 nM，对c-Met N1100Y 的IC50=2.0 nM。
T19723	AMTB hydrochloride AMTB	TRP/TRPV Channel	Membrane transporter/Ion channel
	AMTB hydrochloride (AMTB HCl) 是TRPM8通道的选择性阻滞剂。它抑制 icilin 诱导的 TRPM8 通道激活，pIC50为 6.23。它在膀胱过度活动和膀胱疼痛综合征中有研究的价值。它是电压门控钠通道的非选择性抑制剂 (NaV)。
T15017	CU-T12-9	TLR	Immunology/Inflammation
	CU-T12-9 是特异性 TLR1/2激动剂，可激活先天免疫系统和适应性免疫系统。它选择性激活 TLR1/2 异二聚体，可通过促进 TLR1 和 TLR2 二聚而激活 NF-κB 信号，引起下游 TNF-α、IL-10 和 iNOS 增加。
T6916	OICR-9429 OICR 9429	Histone Methyltransferase; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	OICR-9429 是一个新颖的相互作用的小分子Wdr5-MLL 拮抗剂，IC50是 5 uM，在体外抑制急性髓性白血病细胞。
T0334	Rosiglitazone BRL49653,罗格列酮	Ferroptosis; TRP/TRPV Channel; PPAR; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Rosiglitazone (BRL49653) 是一种 PPARγ 激动剂、TRPC5 激活剂和 TRPM3 抑制剂，具有口服活性。Rosiglitazone 也是一种降糖剂，是噻唑烷二酮类胰岛素增敏剂。
T6646	Rosiglitazone hydrochloride 盐酸罗格列酮,BRL-49653 HCl,Rosiglitazone HCl	Ferroptosis; TRP/TRPV Channel; PPAR; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Rosiglitazone hydrochloride (BRL-49653 HCl) 是一种降血糖药物，通过与脂肪细胞中的 PPAR 受体结合来刺激胰岛素分泌。它对 PPARγ1、PPARγ2 和 PPARγ 的EC50值分别为 30 nM、100 nM 和 60 nM。它也是TRPC5的激活剂和TRPM3的抑制剂。
T15477	Hexaminolevulinate hydrochloride Hexyl 5-aminolevulinate hydrochloride,5-Aminolevulinic acid hexyl ester hydrochloride,P-1206,5-氨基酮戊酸己酯盐酸盐	Others	Others
	Hexaminolevulinate hydrochloride (P-1206) 是一种被批准的、可用于膀胱镜检测乳头状膀胱癌的荧光剂。
T23888	CID-5056270	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	CID-5056270具有抗癌活性，对肺癌肛门癌、膀胱癌、宫颈癌、外阴癌、阴茎癌、伯基特淋巴瘤乳腺癌和骨癌具有抑制作用，可用来研究高血压、老年痴呆症度、阿尔茨海默病和动脉硬化。
T24051	Exisulind Sulindac sulfone,CP248	Apoptosis; PKA	Apoptosis; Tyrosine Kinase/Adaptors
	Exisulind (CP248) 通过激活蛋白激酶 G (PKG) 诱导细胞凋亡。 Exisulind 在实体瘤和血液癌细胞系中表现出抗肿瘤活性，并且是结肠癌、前列腺癌、膀胱癌、乳腺癌和肺癌啮齿动物模型中肿瘤生长的抑制剂。
T38970	Hematoporphyrin monomethyl ether	Others	Others
	Hematoporphyrin monomethyl ether (HMME), a second-generation porphyrin-related photosensitizer, is a highly selective and low-toxicity compound known for its singular form and high yield of singlet oxygen. It finds extensive application in diagnosing and treating various tumors, including lung cancer, bladder cancer, nevus flammeus, and brain glioma.
T15558	GSK319347A	IκB/IKK	NF-κB
	GSK319347A 是一种具有选择性和有效性的 TBK1 和 IKKε 的双重抑制剂，具有潜在的抗肿瘤活性，对 IKK2 活性有抑制作用，可用于研究膀胱癌和肺腺癌。
T60039	KSQ-4279 USP1-IN-1	PARP; DUB	Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Ubiquitination
	KSQ-4279 (USP1-IN-1)是 USP1 和 PARP 的抑制剂。KSQ-4279 具有抗癌活性，可用于研究非小细胞肺癌、骨肉瘤、卵巢癌、乳腺癌、胶质母细胞瘤、膀胱癌、子宫癌和胰腺癌。
T36898	Sandacanol Sandranol,2-Ethyl-4-(2,2,3-trimethylcyclopent-3-en-yl)-but-2-en-1-ol	Apoptosis	Apoptosis
	Sandacanol（Sandranol）是一种选择性嗅觉受体（OR10H1）激动剂。Sandacanol可诱导膀胱癌细胞的细胞周期停止和部分凋亡，可降低细胞迁移率和增殖率。
T15713	Larotaxel XRP9881	P-gp	Membrane transporter/Ion channel; Neuroscience
	Larotaxel (XRP9881) 是一种紫杉烷类似物，具有抗癌活性，通过促进微管蛋白装配和稳定微管发挥其细胞毒性作用，并通过细胞凋亡诱导细胞死亡。Larotaxel (XRP9881) 是一种可穿过血脑屏障的化合物，对 Docetaxel 的亲和力比 P-糖蛋白 1 高，可用于研究乳腺癌和膀胱癌。
T0976	Propoxur 残杀威,Aprocarb,Propoxure,Baygon	AChR; Antifungal	Microbiology/Virology; Neuroscience
	Propoxur (Propoxure) 是一种氨基甲酸酯类杀虫剂，用于控制蟑螂、苍蝇、蚊子以及草坪和草坪昆虫。
T25892	N-Trifluoroacetyladriamycin NSC-283464,NSC 283464,AD 41,AD-41,NSC283464	Others	Others
	N-Trifluoroacetyladriamycin is a metabolite of Valrubicin (N-trifluoroacetyladriamycin-14-valerate, trade name Valstar). Valrubicin is a chemotherapy drug utilized to treat bladder cancer. Valrubicin is the anthracycline doxorubicin analog and is administ
T70512	Isobetanin	Others	Others
	Isobetanin is a betacyanin that has been shown to enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells.
T73826	PZ703b hydrochloride	PROTACs	PROTAC
	PZ703b hydrochloride 是一种Bcl-xlPROTAC 降解剂，可以诱导细胞凋亡 (apoptosis)，抑制癌细胞增殖。PZ703b hydrochloride 可用于膀胱癌的研究。
T74466	ASR-488	Others	Others
	ASR-488 可激活 mRNA 结合蛋白 CPEB1，诱导细胞凋亡 (apoptosis) 并抑制膀胱癌的生长。
T16354	NSC745885	Others	Others
	NSC745885 is an effective down-regulator of EZH2 via proteasome-mediated degradation. NSC745885 is also an effective anti-tumor agent that displays selective toxicity against multiple cancer cell lines but not normal cells. NSC745885 offers possibilities
T77913	PZ703b TFA	PROTACs	PROTAC
	PZ703b TFA为一种Bcl-xl PROTAC降解剂，具备诱导细胞凋亡(apoptosis)及抑制癌细胞增殖功能，主要应用于膀胱癌研究领域。
T74521	Anticancer agent 52	Others	Others
	Anticancer agent 52 是一种有效的抗癌剂。Anticancer agent 52 显示出体外细胞毒性。Anticancer agent 52 诱导细胞凋亡 (apoptosis)。Anticancer agent 52 显示出抗肿瘤作用。Anticancer agent 52 具有研究膀胱癌的潜力。
T81574	PAA4	Others	Others
	PAA4为含中心甲基化物碳的多核Au(I)簇，具有抗增殖活性。PAA4能时间依赖性地提升pH2AX表达，并在原位膀胱癌小鼠模型中展现抗肿瘤效果。
T12068	MK-8033 hydrochloride	Others	Others
	MK-8033 hydrochloride 是一种有效的、具有口服活性的 ATP 竞争性 c-Met/Ron 双重抑制剂，对c-Met 的为1 nM ，对Ron 的IC50为7nM。MK-8033 hydrochloride 对活化的激酶构象 (activated kinase conformation)具有很高的亲和力，可用于乳腺癌，膀胱癌、非小细胞肺癌 (NSCLC)等癌症的研究。
T36882	CAY10773	Others	Others
	CAY10773 is a derivative of the ferroptosis inducer sorafenib .1It selectively inhibits proliferation of BEL-7402, MGC803, and T24 bladder cancer cells (IC50s = 5.77, 5.21 and 3.97 μM, respectively) over non-cancerous HCV-29 cells (IC50= 23.19 μM). CAY10773 induces apoptosis in T24 cells when used at concentrations ranging from 2 to 6 μM but induces ferroptosis at concentrations greater than or equal to 6 μM with 10 hour or longer incubation times. It increases the production of reactive oxygen ...
T70045	HUN47990	Others	Others
	HUN47990 is a bisphosphonate (BP) prodrug with antitumor activity. HUN47990 potently inhibits the in vitro growth of a variety of tumor cell lines, especially hematopoietic cell lines, at nanomolar concentrations. HUN47990 inhibited the prenylation of the RAP1A small GTPase signaling protein at concentrations as low as 1-10 nM. HUN47990 slowed the growth of human bladder cancer cells in an immunodeficient mouse model. HUN47990 is significantly more active than zoledronic acid, the most active FD...
T35616	Migrastatin	Others	Others
	Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic acetylcholine receptors (Kis = >200, 200, 31, 43, and >200 μM, respectively) and inhibits calcium mobilization induced by carbamoylcholine in SK-N-SH cells (IC50= 28 μM), as well as in primary rat bladder smooth muscle cells.1Migrastatin inhibits the migration of EC17 esophageal cancer cells in a wound healing assay (IC50= 10 μg/ml) and 4T1 mouse mam...
T21693	PPM-18	Others	Others
	PPM-18 (NSC 73233) 是一种有效的抗炎剂，可抑制一氧化氮合酶的表达。PPM-18 是有效的 iNOS 表达抑制剂，可阻断 NF-κB 与启动子的结合。PPM-18 是维生素 K 的类似物，通过 ROS 和 AMPK 信号通路诱导膀胱癌细胞自噬和凋亡。
T63351	MS8511	Others	Others
	MS8511 是一种选择性的G9a/GLP 共价的不可逆抑制剂，可靶向底物结合位点的半胱氨酸残基，IC50值为 100 nM ( G9a) 和 140 nM (GLP)，Kd 值44 nM (G9a) 和 46 nM (GLP)。 MS8511 可降低细胞内 H3K9me2 水平并提高抗增殖活性。MS8511 可用于研究多种癌症 (包括脑癌、乳腺癌、卵巢癌、肺癌、膀胱癌、黑色素瘤、结肠直肠癌) 和其他疾病,如阿尔茨海默病 (AD)、镰状细胞病、Prader-Willi 综合征 (PWS).
T72780	HSP90/mTOR-IN-1	Others	Others
	HSP90/mTOR-IN-1 是一种有效的Hsp90和mTOR 抑制剂，IC50分别为 69 nM 和 29 nM。HSP90/mTOR-IN-1 通过过度激活PI3K/AKT/mTOR 通路抑制 SW780 细胞增殖。HSP90/mTOR-IN-1 通过对HSP90和mTOR 的选择性抑制来诱导细胞凋亡 (apoptosis) 和细胞自噬 (autophagy)。HSP90/mTOR-IN-1 在异种移植小鼠体内也表现出良好的抗肿瘤活性。HSP90/mTOR-IN-1 可用于膀胱癌的研究。
T36410	9(E),11(E),13(E)-Octadecatrienoic Acid	Others	Others
	9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner. In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces a...
T63399	mTOR/HDAC-IN-1	Others	Others
	mTOR/HDAC-IN-1 (Compound 50) 是一个具有选择性的mTOR 和HDAC 双重抑制剂，对mTOR 和HDAC1的IC50分别为0.49和0.91 nM。 mTOR/HDAC-IN-1 可作为抗癌活性分子（anti-cancer）进行研究。该化合物的粉末形式不稳定，建议选择其他盐形式产品。

化合物

Cat.No: TQ0219

Target: c-Met/HGFR

AMTB hydrochloride

Cat.No: T19723

Synonym: AMTB

Target: TRP/TRPV Channel

Cat.No: T15017

Target: TLR

Cat.No: T6916

Synonym: OICR 9429

Target: Histone Methyltransferase, JAK

Cat.No: T0334

Synonym: BRL49653,罗格列酮

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Rosiglitazone hydrochloride

Cat.No: T6646

Synonym: 盐酸罗格列酮,BRL-49653 HCl,Rosiglitazone HCl

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Hexaminolevulinate hydrochloride

Cat.No: T15477

Synonym: Hexyl 5-aminolevulinate hydrochloride,5-Aminolevulinic acid hexyl ester hydrochloride,P-1206,5-氨基酮戊酸己酯盐酸盐

Target: Others

Cat.No: T23888

Target: ROCK

Cat.No: T24051

Synonym: Sulindac sulfone,CP248

Target: Apoptosis, PKA

Hematoporphyrin monomethyl ether

Cat.No: T38970

Target: Others

Cat.No: T15558

Target: IκB/IKK

Cat.No: T60039

Synonym: USP1-IN-1

Target: PARP, DUB

Cat.No: T36898

Synonym: Sandranol,2-Ethyl-4-(2,2,3-trimethylcyclopent-3-en-yl)-but-2-en-1-ol

Target: Apoptosis

Cat.No: T15713

Synonym: XRP9881

Target: P-gp

Cat.No: T0976

Synonym: 残杀威,Aprocarb,Propoxure,Baygon

Target: AChR, Antifungal

N-Trifluoroacetyladriamycin

Cat.No: T25892

Synonym: NSC-283464,NSC 283464,AD 41,AD-41,NSC283464

Target: Others

Cat.No: T70512

Target: Others

PZ703b hydrochloride

Cat.No: T73826

Target: PROTACs

Cat.No: T74466

Target: Others

Cat.No: T16354

Target: Others

Cat.No: T77913

Target: PROTACs

Anticancer agent 52

Cat.No: T74521

Target: Others

Cat.No: T81574

Target: Others

MK-8033 hydrochloride

Cat.No: T12068

Target: Others

Cat.No: T36882

Target: Others

Cat.No: T70045

Target: Others

Cat.No: T35616

Target: Others

Cat.No: T21693

Target: Others

Cat.No: T63351

Target: Others

HSP90/mTOR-IN-1

Cat.No: T72780

Target: Others

9(E),11(E),13(E)-Octadecatrienoic Acid

Cat.No: T36410

Target: Others

Cat.No: T63399

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3S0737	Flavokawain A 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A	Apoptosis; p38 MAPK	Apoptosis; MAPK
	Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮，是一种抗癌试剂，具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡，有潜力用于膀胱癌的相关研究。
T4S0350	Licochalcone B 甘草查尔酮 B,甘草查尔酮B	Beta Amyloid; Others	Neuroscience; Others
	Licochalcone B 是从Glycyrrhiza inflate 根中提取的。它能够抑制淀粉样蛋白 β 自聚集作用 (IC50=2.16 μM) ，分解预先形成的 Aβ42原纤维，并通过螯合金属离子抑制金属诱导的 Aβ42聚集。
TN1512	Clinopodiside A	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Clinopodiside A 是一种从 Clinopodium polycephalum 中分离出来的三萜皂苷，具有抗肿瘤活性，通过 T24 膀胱癌细胞中 BLK 和 RasGRP2 信号传导介导的自噬诱导细胞毒性。
T5715	(E)-Flavokawain A (E)-1-(2-羟基-4,6-二甲氧基苯基)-3-(4-甲氧基苯基)-2-丙烯-1-酮,FLAVOKAVAIN A(P),卡瓦胡椒素A	Apoptosis; P450	Apoptosis; Metabolism
	(E)-Flavokawain A 是一种来自卡瓦提取物的新型查尔酮，通过参与 Bax 蛋白依赖性和线粒体依赖性凋亡途径诱导膀胱癌细胞凋亡，并抑制小鼠肿瘤生长，具有抗癌作用。
T7028	Licochalcone C LICOCHALCONEC,甘草查尔酮C	Phosphatase; Antioxidant; Glucosidase	Metabolism; oxidation-reduction
	Licochalcone C (LICOCHALCONEC) 能够抑制 α-葡萄糖苷酶，其对 α-葡萄糖苷酶的 IC50 <100 nM，对蛋白酪氨酸磷酸酶 1B 的 IC50=92.43 μM 。
TN4382	Kazinol A	AMPK; mTOR	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M against XOD. Kazinol A may be a candidate for the development of effective anti-cancer drug on h
T4366	Quinovic acid	NF-κB; Caspase	Apoptosis; NF-κB; Proteases/Proteasome
	Quinovic acid shows some anti-tumour activities, quinovic acid glycosides have a potent inhibitory effect on the growth of human bladder cancer cell lines by inducing apoptosis through modulation of NF-ÎºB.
TN3404	Altholactone	BCL; p38 MAPK; ROS; Akt; Caspase; Antifection; p53	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of various types of cancer cells through inducing apoptosis via oxidative stress, including bladd

天然产物

Cat.No: T3S0737

Synonym: 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A

Target: Apoptosis, p38 MAPK

Cat.No: T4S0350

Synonym: 甘草查尔酮 B,甘草查尔酮B

Target: Beta Amyloid, Others

Clinopodiside A

Cat.No: TN1512

Target: DNA/RNA Synthesis

(E)-Flavokawain A

Cat.No: T5715

Synonym: (E)-1-(2-羟基-4,6-二甲氧基苯基)-3-(4-甲氧基苯基)-2-丙烯-1-酮,FLAVOKAVAIN A(P),卡瓦胡椒素A

Target: Apoptosis, P450

Cat.No: T7028

Synonym: LICOCHALCONEC,甘草查尔酮C

Target: Phosphatase, Antioxidant, Glucosidase

Cat.No: TN4382

Target: AMPK, mTOR

Cat.No: T4366

Target: NF-κB, Caspase

Cat.No: TN3404

Target: BCL, p38 MAPK, ROS, Akt, Caspase, Antifection, p53

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03747	CCDC112 Protein, Human, Recombinant (His & Myc) Mutated in bladder cancer protein 1,Coiled...	Human	E. coli
	CCDC112 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.0 kDa and the accession number is Q8NEF3.
TMPY-05030	PCDH7 Protein, Human, Recombinant (His) BHPCDH	Human	Baculovirus Insect Cells
	PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number...
TMPY-04263	UBE2T Protein, Human, Recombinant (His) FANCT,PIG50,ubiquitin-conjugating enzyme E2T,HSPC150	Human	E. coli
	Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive target for the development of inhibitors. Notably, UBE2T locates at 1q32.1, and the gain of 1q is frequently observed in a variety of cancers. For instance, UBE2T serves an important role in the growth of bladder cancer cells, and may be considered as a potential biomarker and therapeutic target for bladder cancer.
TMPY-02220	HRAS Protein, Human, Recombinant (His) HAMSV,Harvey rat sarcoma viral oncogene homolog,C-H-RAS,C-HA...	Human	Baculovirus Insect Cells
	HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Defects in HRAS are the cause of faciocutaneoskeletal syndrome (FCSS). FCSS is a rare condition characterized by prenatally increase...
TMPY-06762	PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated BHPCDH	Human	Baculovirus Insect Cells
	PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 95....
TMPK-01220	CD164 Protein, Mouse, Recombinant (hFc) CD164,Endolyn,MGC-24v,sialomucin,MUC-24,MGC-24	Mouse	HEK293 Cells
	CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients.CD164 was associated with the poor clinical outcomes of BC patients. Silencing of CD164 could inhibit the progression of tumors in vivo and in vitro, which may become an effective target in the treatment of bladder cancer. CD164 Protein, Mouse, Recombinant (hF...
TMPK-00931	CD164 Protein, Human, Recombinant (hFc) MGC-24v,MUC-24,sialomucin,Cd164,Endolyn,MGC-24	Human	HEK293 Cells
	CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients.CD164 was associated with the poor clinical outcomes of BC patients. Silencing of CD164 could inhibit the progression of tumors in vivo and in vitro, which may become an effective target in the treatment of bladder cancer. CD164 Protein, Human, Recombinant (hF...
TMPK-00906	PSCA Protein, Mouse, Recombinant (hFc) UNQ206,PSCA,PRO232	Mouse	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Mouse, Recomb...
TMPK-00728	PSCA Protein, Human, Recombinant (hFc) UNQ206,PRO232,PSCA	Human	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Human, Recomb...
TMPJ-01381	ANXA10 Protein, Human, Recombinant Annexin-10,ANX14,Annexin-14,ANXA10,Annexin A10	Human	E. coli
	Annexin A10 (ANXA10) contains four Annexin repeats and is a member of the Annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is reported that ANXA10 may be a clinical relevant marker for predicting outcome in both early and advanced stages of bladder cancer.
TMPY-00507	UNC5B Protein, Human, Recombinant (hFc) unc-5 homolog B (C. elegans),UNC5H2,p53RDL1	Human	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular ...
TMPY-04133	UNC5B Protein, Human, Recombinant (His) UNC5H2,p53RDL1,unc-5 homolog B (C. elegans)	Human	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular ...
TMPY-04003	UNC5B Protein, Rat, Recombinant (hFc) unc-5 homolog B (C. elegans)	Rat	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular we...
TMPY-04899	OGN/Osteoglycin Protein, Human, Recombinant (His) OIF,OG,osteoglycin,SLRR3A	Human	HEK293 Cells
	OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor-beta and may regulate osteoblast differentiation. OGN is broadly expressed in the gall bladder, endometrium, and other tissues. OGN reduced Zeb-1 expression via EGFR/Akt leading to inhibition of epith...
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His) 5F7,TCSF,OK Blood Group Antigen,Tumor Cell-Derived Collagena...	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion,...
TMPY-00648	UNC5A Protein, Human, Recombinant (hFc) UNC5H1,unc-5 homolog A (C. elegans)	Human	HEK293 Cells
	The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,...
TMPY-04930	Notch 2 Protein, Human, Recombinant (His) AGS2,HJCYS,hN2,notch 2	Human	Baculovirus Insect Cells
	NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of developmental processes by controlling cell fate decisions. Hajdu Cheney Syndrome (HCS) is a rare disease associated with mutations of NOTCH2 that lead to the translation of a truncated, presumably stable, NOTCH2 protein. NOTCH2 is down-regulated in colon cancer, and reduced express...
TMPY-00999	UNC5A Protein, Human, Recombinant (His) unc-5 homolog A (C. elegans),UNC5H1	Human	HEK293 Cells
	The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,...
TMPY-02384	MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP) metastasis suppressor 1,MIMB,MIM,MIMA	Human	E. coli
	MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO) ADAR1,IFI-4,136 kDa double-stranded RNA-binding protein,Inte...	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...

重组蛋白

CCDC112 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-03747

Species: Human

Expression System: E. coli

PCDH7 Protein, Human, Recombinant (His)

Cat.No: TMPY-05030

Species: Human

Expression System: Baculovirus Insect Cells

UBE2T Protein, Human, Recombinant (His)

Cat.No: TMPY-04263

Species: Human

Expression System: E. coli

HRAS Protein, Human, Recombinant (His)

Cat.No: TMPY-02220

Species: Human

Expression System: Baculovirus Insect Cells

PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06762

Species: Human

Expression System: Baculovirus Insect Cells

CD164 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01220

Species: Mouse

Expression System: HEK293 Cells

CD164 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00931

Species: Human

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00906

Species: Mouse

Expression System: HEK293 Cells

PSCA Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00728

Species: Human

Expression System: HEK293 Cells

ANXA10 Protein, Human, Recombinant

Cat.No: TMPJ-01381

Species: Human

Expression System: E. coli

UNC5B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00507

Species: Human

Expression System: HEK293 Cells

UNC5B Protein, Human, Recombinant (His)

Cat.No: TMPY-04133

Species: Human

Expression System: HEK293 Cells

UNC5B Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04003

Species: Rat

Expression System: HEK293 Cells

OGN/Osteoglycin Protein, Human, Recombinant (His)

Cat.No: TMPY-04899

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00160

Species: Human

Expression System: HEK293 Cells

UNC5A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00648

Species: Human

Expression System: HEK293 Cells

Notch 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04930

Species: Human

Expression System: Baculovirus Insect Cells

UNC5A Protein, Human, Recombinant (His)

Cat.No: TMPY-00999

Species: Human

Expression System: HEK293 Cells

MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)

Cat.No: TMPY-02384

Species: Human

Expression System: E. coli

ADAR Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01248

Species: Human

Expression System: E. coli

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