|
TMPH-03290
|
GFER Protein, Rat, Recombinant (His & SUMO)
FAD-linked sulfhydryl oxidase ALR,Gfer,Augmenter of liver
|
Rat
|
E. coli
|
|
GFER Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.8 kDa and the accession number is Q63042. |
|
TMPJ-01020
|
GFER Protein, Human, Recombinant (His)
Augmenter of liver regeneration,FAD-linked sulfhydr...
|
Human
|
E. coli
|
|
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ER... |
|
TMPH-03371
|
Transferrin Protein, Rat, Recombinant (His & KSI)
Tf,Beta-1 metal-binding globulin,Liver regeneration...
|
Rat
|
E. coli
|
|
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Transferrin Protein, Rat, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight ... |
|
TMPY-00368
|
ALR Protein, Human, Recombinant (His)
HPO,ERV1,HERV1,ALR,HSS,HPO2,growth factor, augmenter of live...
|
Human
|
HEK293 Cells
|
|
Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis and respiratory chain deficiency in 3 siblings born to consanguineous Moroccan parents by homozygosity mapping and candidate gene approach. Using homozygosity mapping, we discovered that a mutation in the GFER gene causes an infantile mitochondrial disorder. |
|
TMPJ-00090
|
FGF-9 Protein, Human, Recombinant
Fibroblast Growth Factor 9,Heparin-Binding Growth Factor 9,F...
|
Human
|
E. coli
|
|
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial c... |
|
TMPY-03382
|
FGF-6 Protein, Human, Recombinant
HBGF-6,HST2,fibroblast growth factor 6
|
Human
|
E. coli
|
|
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. It is also required for normal muscle regeneration. FGF6 gene d... |
|
TMPY-05004
|
FGF-4 Protein, Human, Recombinant
HST-1,KFGF,fibroblast growth factor 4,HSTF1,K-FGF,HST,HBGF-4
|
Human
|
E. coli
|
|
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) a... |
|
TMPJ-00662
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Receptor activator of nuclear factor kappa-B ligand,Receptor...
|
Human
|
E. coli
|
|
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog... |
|
TMPJ-00375
|
HGF Protein, Human, Recombinant (His)
Scatter factor,Hepatocyte growth factor,HGF,SF,Hepatopoietin...
|
Human
|
HEK293 Cells
|
|
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelia... |
|
TMPJ-01011
|
FGF-9 Protein, Mouse, Recombinant (His)
heparin-binding growth factor-9,GAF,HBGF-9,Glia-activating f...
|
Mouse
|
E. coli
|
|
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v... |
|
TMPH-02546
|
ENO3 Protein, Mouse, Recombinant (His)
Eno3,Beta-enolase,Skeletal muscle enolase,Muscle-specific en...
|
Mouse
|
P. pastoris (Yeast)
|
|
Appears to have a function in striated muscle development and regeneration. |
|
TMPH-02806
|
Nav3 Protein, Mouse, Recombinant (His)
Neuron navigator 3,Pore membrane and/or filament-interacting...
|
Mouse
|
E. coli
|
|
May regulate IL2 production by T-cells. May be involved in neuron regeneration. |
|
TMPH-01542
|
ITIH4 Protein, Human, Recombinant (His & SUMO)
Inter-alpha-trypsin inhibitor heavy chain H4,ITIH4,Plasma ka...
|
Human
|
E. coli
|
|
Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. |
|
TMPH-01541
|
ITIH4 Protein, Human, Recombinant (His)
ITIH4,Inter-alpha-trypsin inhibitor heavy chain H4,Inter-alp...
|
Human
|
P. pastoris (Yeast)
|
|
Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. |
|
TMPH-02547
|
ENO3 Protein, Mouse, Recombinant (His & Myc)
Skeletal muscle enolase,Eno3,Enolase 3,2-phospho-D-glycerate...
|
Mouse
|
E. coli
|
|
Appears to have a function in striated muscle development and regeneration. ENO3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.3 kDa and the accession number is P21550. |
|
TMPH-02629
|
ADAM12 Protein, Mouse, Recombinant (His & Myc)
Disintegrin and metalloproteinase domain-containing protein ...
|
Mouse
|
Baculovirus Insect Cells
|
|
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. ADAM12 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.4 kDa and the accession number is Q61824. |
|
TMPY-04934
|
Serpin A3n Protein, Rat, Recombinant (His)
serine (or cysteine) peptidase inhibitor, clade A, member 3N
|
Rat
|
HEK293 Cells
|
|
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal muscle resident proteases during injury or dystrophic disease, which stabilizes the sarcolemma leading to less myofiber degeneration and increased regeneration. |
|
TMPH-01610
|
LINGO1 Protein, Human, Recombinant (His)
Leucine-rich repeat neuronal protein 6A,LINGO1,Leucine-rich ...
|
Human
|
E. coli
|
|
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. |
|
TMPY-03446
|
ENO3 Protein, Human, Recombinant (His)
enolase 3 (beta, muscle),GSD13,MSE,enolase 3 (β, muscle)
|
Human
|
E. coli
|
|
ENO3 is one of the three enolase isoenzymes found in mammals. As a homodimer, ENO3 is found in skeletal muscle cells in the adult. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in ENO3 gene can be associated with metabolic myopathies that may result from decreased stability of the enzyme. Two transcripts have been identified for ENO3 gene that differ only in their 5' UTR. ENO3 may play a role in muscle development and regenera... |
|
TMPK-01200
|
Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His)
NGR,NOGOR,RTN4R,NgR1,Nogo receptor,Nogo-66 receptor
|
Cynomolgus
|
HEK293 Cells
|
|
NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes. |
|
TMPJ-00821
|
OM Protein, Human, Recombinant (His)
Oncomodulin-1,OCM,OM,OCMN,Parvalbumin Beta,Parvalbumin β,OCM...
|
Human
|
E. coli
|
|
Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to... |
|
TMPK-00153
|
BAMBI Protein, Human, Recombinant (hFc)
Bambi,Nma
|
Human
|
HEK293 Cells
|
|
Bone morphogenic protein and activin membrane-bound inhibitor (BAMBI) is a transmembrane protein that affects the growth, development and muscle regeneration of the body by regulating the TGF-β, BMP and Wnt signaling pathways. In brief, BAMBI may be a functional gene for the differentiation of bovine preadipocytes and myoblasts, and variations in the BAMBI genomic region, especially the combined haplotype H1H4, may benefit marker-assisted selection in cattle. |
|
TMPH-01796
|
NR4A1 Protein, Human, Recombinant (His & Myc)
ST-59,NR4A1,Nuclear hormone receptor NUR/77,Orphan nuclear r...
|
Human
|
E. coli
|
|
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury. NR4A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expre... |
|
TMPH-02187
|
Tenascin Protein, Human, Recombinant (E. coli, His)
GMEM,Glioma-associated-extracellular matrix antigen,Neuronec...
|
Human
|
E. coli
|
|
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. |
|
TMPY-03216
|
GMF beta/GMFB Protein, Human, Recombinant
GMF β/GMFB,glia maturation factor, β,glia maturation factor,...
|
Human
|
E. coli
|
|
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production... |
|
TMPH-03345
|
Oncostatin M/OSM Protein, Rat, Recombinant (His)
Oncostatin-M,Osm
|
Rat
|
HEK293 Cells
|
|
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. Oncostatin M/OSM Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 24.2 kDa and ... |
|
TMPH-02753
|
LINGO1 Protein, Mouse, Recombinant (His)
Leucine-rich repeat neuronal protein 6A,Leucine-rich repeat ...
|
Mouse
|
E. coli
|
|
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. LINGO1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pre... |
|
TMPJ-00024
|
GMF beta/GMFB Protein, Human, Recombinant (His)
GMF-β,GMF-beta,GMFB,Glia maturation factor beta,Glia maturat...
|
Human
|
E. coli
|
|
Glia maturation factor beta (GMFB) contains a ADF-H domain，which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results... |
|
TMPJ-00366
|
GAS6 Protein, Human, Recombinant (hFc)
AXLLG,Gas6,GAS-6,AXLLGAXL stimulatory factor,growth arrest-s...
|
Human
|
HEK293 Cells
|
|
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ... |
|
TMPJ-00813
|
QDPR Protein, Human, Recombinant (His)
Dihydropteridine Reductase,QDPR,DHPR,HDHPR,Quinoid Dihydropt...
|
Human
|
HEK293 Cells
|
|
Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals i... |
|
TMPY-04999
|
GAS6 Protein, Human, Recombinant (His)
|
Human
|
HEK293 cells
|
|
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ... |
|
TMPJ-00295
|
NgR Protein, Mouse, Recombinant (hFc)
Nogo-66 Receptor,Nogo Receptor,NgR,RTN4R,NOGOR,Reticulon-4 R...
|
Mouse
|
HEK293 Cells
|
|
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be prop... |
|
TMPJ-00365
|
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
AXLLG,Growth arrest-specific protein 6,AXL receptor tyrosine...
|
Human
|
HEK293 Cells
|
|
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, plat... |
|
TMPJ-01089
|
TFF1 Protein, Mouse, Recombinant (His)
Bcei,Protein pS2,Ps2,Trefoil factor 1,Tff1
|
Mouse
|
HEK293 Cells
|
|
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing.It originates from musculus and highly expressed by goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells. TFF1 is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and fo... |
|
TMPY-01551
|
Serpin B8 Protein, Mouse, Recombinant (His)
CAP-2,serpin peptidase inhibitor, clade B (ovalbumin), membe...
|
Mouse
|
Baculovirus Insect Cells
|
|
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal... |
|
TMPY-04761
|
Creatine kinase B Protein, Human, Recombinant (His)
HEL-S-29,CKBB,HEL-211,creatine kinase, brain,BCK,B-CK
|
Human
|
Baculovirus Insect Cells
|
|
CKB(Creatine kinase B type) contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. It belongs to the ATP:guanido phosphotransferase family. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CKB forms tightly coupled microcompartments ... |
|
TMPJ-00277
|
NgR3 Protein, Human, Recombinant (His)
NGRL2,Nogo Receptor-Like 2,Reticulon-4 Receptor-Like 1,NgR3,...
|
Human
|
HEK293 Cells
|
|
Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ... |
|
TMPJ-00781
|
LR3-IGF-1 Protein, Mouse, Recombinant (His)
IGF1,insulin-like growth factor 1,Insulin-like growth factor...
|
Mouse
|
E. coli
|
|
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IG... |
|
TMPY-02106
|
GAP43 Protein, Human, Recombinant (His)
B-50,PP46,growth associated protein 43
|
Human
|
HEK293 Cells
|
|
Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-5, pp46 and GAP43, is a cell membrane protein which belongs to theneuromodulin family. Neuromodulin / GAP43 contains oneIQ domain. Neuromodulin / GAP43 is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Neuromodulin / GAP43 is involved in neurite outgrowth, a crucial process for the differentiation of n... |
|
TMPJ-01459
|
FGF-21 Protein, Cynomolgus, Recombinant (His)
Fibroblast Growth Factor 21,FGF-21,FGF21
|
Cynomolgus
|
HEK293 Cells
|
|
Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diab... |
|
TMPY-01847
|
REG3D Protein, Mouse, Recombinant (His)
Reg3d,regenerating islet-derived 3 delta,Ingaprp,MGC130575,I...
|
Mouse
|
HEK293 Cells
|
|
Regenerating islet-derived 3 delta (REG3D) is a member of the secreted Reg superfamily and contains one typical C-type lectin domain. Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on t... |
|
TMPH-02571
|
CD9 Protein, Mouse, Recombinant (His)
CD9 antigen,CD9
|
Mouse
|
E. coli
|
|
Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD9 and... |
|
TMPJ-00490
|
Serpin A5 Protein, Human, Recombinant (His)
Plasminogen Activator Inhibitor 3,Acrosomal Serine Protease ...
|
Human
|
HEK293 Cells
|
|
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o... |
|
TMPY-00821
|
HGFA Protein (pro form), Human, Recombinant (His)
MGC138397,HGFA,RP11-529E1.2,肝细胞生长因子,MGC138395
|
Human
|
HEK293 Cells
|
|
HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is clea... |
|
TMPY-01406
|
REG3G Protein, Human, Recombinant (His)
UNQ429,PAP-1B,LPPM429,REG-III,regenerating islet-derived 3 γ...
|
Human
|
HEK293 Cells
|
|
Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on the primary structures of the encoded proteins of the genes, which are associated with tissue repair and have been directly implicated ... |
|
TMPY-01000
|
BVES Protein, Human, Recombinant (GST)
CARICK,LGMD2X,POP1,blood vessel epicardial substance,POPDC1,...
|
Human
|
E. coli
|
|
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protective role both in ulcerative and infectious colitis and identify BVES as a critical protector of colonic mucosal integrity. The Popeye domain containing1, also called Bves (Popdc1/Bves), is a transmembrane protein that functions in muscle regeneration, heart rate regulation, hypoxi... |
|
TMPH-02524
|
Arginase-1/ARG1 Protein, Mouse, Recombinant (His)
Arginase-1,Type I arginase,Liver-type arginase,Arg1
|
Mouse
|
P. pastoris (Yeast)
|
|
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.; Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available i... |
|
TMPJ-00521
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CHL2 Protein, Mouse, Recombinant (His)
CHRDL2,chordin-like 2,chordin-like protein 2,BNF-1
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Mouse
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HEK293 Cells
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Mouse Chordin-Like 2, also known as CHL2, is a novel chordin family member with structural homology to CHL1 which is implicated in tumor angiogenesis. The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25 aa signal peptide. The mature chain of CHL2 protein contains two potential N-linked glycosylation sites, one putative NLS and three 63 aa cysteine-rich von Willebrand type C repeats (CRs). CHL2 gene is weakly expressed in the liver and kidney, partly expressed in the connective ... |
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TMPH-02690
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PLA2G10 Protein, Mouse, Recombinant (His & Myc)
Pla2g10,Group X secretory phospholipase A2,Phosphatidylcholi...
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Mouse
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E. coli
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Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li... |
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TMPH-01282
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ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO)
PNEM,ELAVL4,HuD,Hu-antigen D,ELAV-like protein 4
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Human
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E. coli
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RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in the 3' untranslated region (UTR) of target mRNAs, including GAP43, VEGF, FOS, CDKN1A and ACHE mRNA. Many of the target mRNAs are coding for RNA-binding proteins, transcription factors and proteins involved in RNA processing and/or neuronal development and function. By binding to th... |
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