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Darizmetinib (HRX215, HRX-0215) 是一种MKK4抑制剂,MKK4 的抑制导致 MKK7 和 JNK1 信号通路的增强,进而激活转录因子 ATF2 和 ELK1,促进细胞增殖和肝再生。
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Darizmetinib (HRX215, HRX-0215) 是一种MKK4抑制剂,MKK4 的抑制导致 MKK7 和 JNK1 信号通路的增强,进而激活转录因子 ATF2 和 ELK1,促进细胞增殖和肝再生。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,760 | 现货 | |
5 mg | ¥ 3,880 | 现货 | |
10 mg | ¥ 5,530 | 现货 | |
25 mg | ¥ 8,280 | 现货 | |
50 mg | ¥ 10,900 | 现货 | |
100 mg | ¥ 14,800 | 现货 | |
200 mg | ¥ 19,800 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 3,880 | 现货 |
产品描述 | Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration. |
别名 | HRX215, HRX-0215 |
分子量 | 457.45 |
分子式 | C21H17F2N5O3S |
CAS No. | 2369583-33-3 |
Smiles | O=C(C1=NNC2=NC=C(C=C21)C=3C=CN=CC3)C4=CC=C(F)C(NS(=O)(=O)CCC)=C4F |
存储 | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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