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TMPH-02447
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GH Protein, Rhesus macaque, Recombinant (His & Myc)
Growth hormone,Growth hormone 1,Somatotropin,GH1,Pituita...
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Rhesus
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E. coli
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Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH Protein, Rhesus macaque, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.7 kDa and the accession number is ... |
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TMPH-01092
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CHGA Protein, Human, Recombinant (His)
SP-I,Pituitary secretory protein I,CHGA,CgA,Chromog...
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Human
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P. pastoris (Yeast)
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CHGA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P10645. |
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TMPY-02648
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PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)
adenylate cyclase activating polypeptide 1 (pituitary
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Human
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HEK293 Cells
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Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors ( Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediated in part by plasma membrane G protein-dependent activation of adenylyl cyclase and downstream signaling cascades. Studies point to the potential role of the (pituitary) adenylate cyclase activating polypeptide receptor 1 (ADCYAP1R1) gene, which has been implicated in stress resp... |
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TMPH-00488
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Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His)
Follicle-stimulating hormone alpha chain,Glycoprotein hormon...
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Canine
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P. pastoris (Yeast)
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Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His) is expressed in Yeast. |
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TMPH-00489
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Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His & Myc)
Follitropin alpha chain,CGA,Luteinizing hormone alpha chain,...
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Canine
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E. coli
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Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His & Myc) is expressed in E. coli. |
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TMPJ-01471
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Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Activin A,INHBA,Inhibin beta A chain,Inhibin β A chain
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Human/Mouse/Rat
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HEK293 Cells
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Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell developm... |
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TMPY-04853
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TSHR Protein, Human, Recombinant (His)
TSHR,hTSHR-I,TSH Receptor,LGR3,CHNG1
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Human
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Baculovirus Insect Cells
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Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis. |
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TMPJ-00842
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FGF-2 Protein, Rat, Recombinant
bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblast Growth ...
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Rat
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E. coli
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FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g... |
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TMPJ-01016
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INHBC Protein, Human, Recombinant (N-His)
Activin Beta-C Chain,INHBC,Inhibin β C Chain,Activin β-C Cha...
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Human
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E. coli
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Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins,Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary... |
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TMPK-01020
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FSHB Protein, Mouse, Recombinant (hFc)
FSH-beta,FSH-B,FSHB,FSH-β,Follitropin
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Mouse
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HEK293 Cells
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Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Mouse, Recombinant (hFc) is expressed in HE... |
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TMPH-02608
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Corticoliberin Protein, Mouse, Recombinant (His & KSI)
Crh,CRF,Corticotropin-releasing hormone,Gm1347,Corticoliberi...
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Mouse
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E. coli
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Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile. |
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TMPH-01530
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INHBA Protein, Human, Recombinant (His & SUMO)
Activin beta-A chain,INHBA,Inhibin beta A chain,Erythroid di...
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Human
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E. coli
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Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of a... |
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TMPK-01285
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FSHB Protein, Cynomolgus, Recombinant (His)
Follitropin,FSH-B,FSH-beta,FSH-β,FSHB
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Cynomolgus
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HEK293 Cells
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Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Cynomolgus, Recombinant (His) is expressed ... |
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TMPK-00861
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A2AR Protein-VLP, Human, Recombinant
RDC8,Adenosine A2a R,ADORA2,ADORA 2,ADORA2A,A2aR
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Human
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HEK293 Cells
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Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult. |
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TMPH-03112
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GHR Protein, Pig, Recombinant (His)
Growth hormone receptor,GHR,Somatotropin receptor
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Sus scrofa (Pig)
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E. coli
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Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Pig, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is P19756. |
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TMPH-02440
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GHR Protein, Rhesus macaque, Recombinant (His)
GHR,Somatotropin receptor,Growth hormone receptor
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Rhesus
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E. coli
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Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rhesus macaque, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.2 kDa and the accession number is P79194. |
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TMPH-03204
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GHR Protein, Rabbit, Recombinant (His & Myc)
GHR,Somatotropin receptor,Growth hormone receptor
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Rabbit
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E. coli
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Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P19941. |
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TMPY-06821
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THRB Protein, Human, Recombinant (His)
THRB1,GRTH,THR1,ERBA2,C-ERBA-2,THRB2,thyroid hormone recepto...
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Human
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E. coli
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Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-binding domain, THRB isoform 1/2 expression localizes predominately to the liver and pituitary, respectively. THRB regulates the feedback of T3-dependent thyrotropin-stimulating hormone (TSH) transcription in the pituitary by binding to thyroid hormone (TH) response elements present... |
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TMPY-02839
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Adrenomedullin Protein, Human, Recombinant (hFc)
AM,PAMP,adrenomedullin
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Human
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HEK293 Cells
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Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the calcitonin gene-related peptide. Adrenomedullin has a highly expression in pheochromocytoma and adrenal medulla. It also can be detected in lung, ventricle and kidney tissues. Adrenomedullin and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been report... |
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TMPJ-00517
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WIF-1 Protein, Human, Recombinant (His)
Wnt Inhibitory Factor 1,WIF-1,WIF1
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Human
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HEK293 Cells
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Wnt Inhibitory Factor 1 (WIF1) is a secreted protein, which binds WNT proteins and inhibits their activities. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. is found to be present in fish, amphibia and mammals. WIF1 is a recurrent target in human salivary gland oncogenesis.WIF1 may be involved in mesoderm segmentation. WIF1 is a tumor suppress... |
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TMPH-02522
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GHRL Protein, Mouse, Recombinant (His)
Motilin-related peptide,Growth hormone-releasing peptide,Gro...
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Mouse
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E. coli
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Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. GHRL Protein, Mouse, Recombinant (His) is expressed in E. coli expre... |
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TMPJ-00482
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SEMG1 Protein, Human, Recombinant (His)
SGI,SEMG,Semenogelin-1,Seminal Basic Protein,Alpha-Inhibin-3...
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Human
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HEK293 Cells
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Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alpha-inhibin-92 and alpha-inhibin-31 are produced; they inhibit the secretion of pituitary follicle-stimulating hormone. At the same time, it breaks... |
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TMPH-02078
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Semenogelin-1/SEMG1 Protein, Human, Recombinant (His & SUMO)
Cancer/testis antigen 103,Semenogelin I,Semenogelin-1,SEMG1
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Human
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E. coli
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Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.; Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone. Sem... |
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TMPJ-00356
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GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)
GHBP,GHR,Somatotropin receptor,growth hormone receptor,growt...
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Mouse
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HEK293 Cells
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Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway lead... |
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TMPJ-01015
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INHBC Protein, Human, Recombinant (C-His)
Activin β-C Chain,Activin Beta-C Chain,Inhibin β C Chain,INH...
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Human
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HEK293 Cells
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Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only. Inhibins/activins regulates many physiological processes, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell ... |
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TMPY-02849
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WIF1 Protein, Mouse, Recombinant (His)
AW107799,WIF-1,WNT inhibitory factor 1
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Mouse
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HEK293 Cells
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WIF1, also known as WIF-1 and wnt inhibitory factor 1, is a secreted protein that binds WNT proteins and inhibits their activities. It contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 may be involved in mesoderm segmentation and can be detected in fish, amphibia and mammals. WIF-1 is a recurrent target in human salivary gland oncogenesis. Downre... |
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TMPH-02878
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PTPRS Protein, Mouse, Recombinant (His & Myc)
Receptor-type tyrosine-protein phosphatase S,Ptprs,PTPNU-3,R...
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Mouse
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E. coli
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Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteo... |
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TMPY-01117
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MRAP Protein, Human, Recombinant (hFc)
FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2...
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Human
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HEK293 Cells
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MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece... |
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TMPJ-00906
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CRHBP Protein, Human, Recombinant (His)
CRF-BP,CRF-Binding Protein,Corticotropin-Releasing Factor-Bi...
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Human
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HEK293 Cells
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Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds. Difference between CRHBP from different species exist, human CRHBP is found in plasma while rodent and sheep CRHBP is limited to neuroendocrine tissues. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulatio... |
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TMPY-01551
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Serpin B8 Protein, Mouse, Recombinant (His)
CAP-2,serpin peptidase inhibitor, clade B (ovalbumin), membe...
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Mouse
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Baculovirus Insect Cells
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Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal... |
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TMPY-01875
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SCGN Protein, Human, Recombinant (His)
SEGN,SECRET,DJ501N12.8,CALBL,secretagogin, EF-hand calcium b...
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Human
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E. coli
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Secretagogin, also known as SCGN, is a secreted protein that is detectable in human serum after ischemic neuronal damage. It is a recently described calcium-binding protein. Secretagogin / SCGN is expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression of Secretagogin / SCGN is restricted to distinct subtypes ... |
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TMPY-02979
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HMGN3 Protein, Human, Recombinant (His)
PNAS-24,TRIP7,PNAS-25,high mobility group nucleosomal bindin...
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Human
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E. coli
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HMGN3 belongs to the HMGN family and is expressed in the kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate, and uterus. Members of the HMGN family bind to nucleosomes without any specificity for the underlying DNA sequence. They affect the global and local structure of chromatin, as well as the levels of histone modifications, and thus play a role in epigenetic regulation of gene expression. HMGN3 regulates the expression of the glucose transporter ... |
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TMPY-01635
|
PCSK1 Protein, Human, Recombinant (His)
proprotein convertase subtilisin/kexin type 1,SPC3,PC1,BMIQ1...
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Human
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HEK293 Cells
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Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleav... |
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TMPY-01190
|
INHBB Protein, Human, Recombinant (His)
inhibin beta B,INHBB,Inhibin β B Protein,MGC157939,inhibin β...
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Human
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HEK293 Cells
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Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two ß subunits, ßA ßA (activin A), ßB ßB (activin B), or ßA ßB (activin AB). Inhibin is composed of an alpha and one of two ß subunits, ßA (inhibin A) or ßB (inhibin B). Activins are produced in... |
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TMPY-00186
|
GHRH Protein, Human, Recombinant (hFc)
GRF,INN,growth hormone releasing hormone,GHRF
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Human
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HEK293 Cells
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The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl... |
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TMPY-01846
|
Activin A Protein, Mouse, Recombinant (His)
inhibin, β A,inhibin, beta A
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Mouse
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HEK293 Cells
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Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in... |
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