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Search Results for " gastric acid "
Targets Recommended: ATPase Proton pump

108

抑制剂 & 化合物

6

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11

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Cat. No. Product Name Target Signaling Pathways
T17030 Tegoprazan

ATPase; Proton pump Membrane transporter/Ion channel
Tegoprazan 是一种口服有效的、高选择性胃 H+/K+-ATP 酶 (H+/K+-ATPase) 抑制剂,能够控制胃酸分泌和运动,在体外检测的对猪、犬、人的 H+/K+-ATP 酶的 IC50为0.29-0.52 μM。
T38612 Linaprazan glurate

Others Others
Linaprazan glurate 抑制外源性或内源性刺激的胃酸分泌。 Linaprazan glurate 可用于胃肠道炎症性疾病和消化性溃疡疾病的研究。
T4579 Pentagastrin

五肽胃泌素,ICI-50123

Others; cholecystokinin GPCR/G Protein; Others
Pentagastrin (ICI-50123) 是一种选择性的胆囊收缩素 B(CCKB) 受体激动剂,IC50=11 nM。它能够增强胃粘膜对酸的防御机制,并保护胃粘膜免受损伤。
T22724 Dimaprit dihydrochloride

NOS; NO Synthase; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Dimaprit dihydrochloride 是组胺H2受体的一种选择性激动剂,可刺激胃酸的分泌。它还抑制nNOS,IC50值为 49 μM。
T4981 Anisotropine Methylbromide

Prostaglandin Receptor; AChR GPCR/G Protein; Immunology/Inflammation; Neuroscience
Anisotropine Methylbromide 是一种抗胆碱能药物,已用于缓解胃肠道痉挛和抑制胃酸分泌。
T0498 Salsalate

Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171,双水杨酸酯

Reactive Oxygen Species; COX Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Salsalate (Sasapyrine) 是一种有效的抗风湿药物,是一种非乙酰化水杨酸盐,可以绕过胃的吸收,也可以避免环氧合酶的抑制。它具有抗炎活性,降低血糖水平、胰岛素抵抗和细胞因子表达,可用于研究 2 型糖尿病。
T0686 Orlistat

Ro-18-0647,奥利司他,Tetrahydrolipstatin

Apoptosis; Others; Fatty Acid Synthase Apoptosis; Metabolism; Others
Orlistat (Tetrahydrolipstatin) 是一种不可逆的胰腺和胃脂肪酶抑制剂,也是一种脂肪酸合成酶抑制剂,可研究肥胖症,具有抗动脉粥样硬化作用。
T6700 Tenatoprazole

泰妥拉唑,TU-199

Proton pump Membrane transporter/Ion channel
Tenatoprazole (TU-199) 是一种口服有效的,基于咪唑吡啶的质子泵抑制剂。它抑制猪胃H+/K+-ATP 酶活性,IC50为6.2 μM。它阻断泛素与 ESCRT-1 因子 Tsg101 的相互作用,抑制几种包膜病毒的产生,包括 EBV。
T8599 Betazole dihydrochloride

盐酸倍他唑,Betazole hydrochloride

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Betazole dihydrochloride (Betazole hydrochloride) 是吡唑类组胺,是一种口服活性 H2受体激动剂,能诱导胃酸分泌,导致胆总管压力立即显著升高。它作为一种诊断剂,用于研究胃酸分泌能力。
T1756L Ilaprazole

IY81149,艾普拉唑,IY 81149,IY-81149

Proton pump; TOPK MAPK; Membrane transporter/Ion channel
Ilaprazole (IY-81149) 是一种具有口服活性质子泵抑制剂,以剂量依赖性方式不可逆地抑制H+/K+-ATPase,在兔壁细胞制剂中的IC50为 6 μM。它也是一种有效的T 细胞起源蛋白激酶(TOPK)抑制剂,用于胃溃疡的研究。
T1756 Ilaprazole sodium

IY-81149 sodium,艾普拉唑钠

Proton pump; TOPK MAPK; Membrane transporter/Ion channel
Ilaprazole sodium (IY-81149 sodium) 是一种具有口服活性质子泵抑制剂,以剂量依赖性方式不可逆地抑制 H+/K+-ATPase,在兔壁细胞制剂中的 IC50为 6 μM。它也是一种有效的 T 细胞起源蛋白激酶(TOPK)抑制剂,用于胃溃疡的研究。
T0674 Lansoprazole

兰索拉唑,A-65006,AG-1749

Proton pump; Phospholipase; Antibacterial Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Lansoprazole (A-65006) 是一种可抑制胃酸生成的质子泵抑制剂。它是中性鞘磷脂酶的外泌体抑制剂。
T8388 Vonoprazan

TAK-438 (free base),沃诺拉赞

Proton pump Membrane transporter/Ion channel
Vonoprazan (TAK-438 (free base)) 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。
T21254 Vonoprazan Fumarate

TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞

Proton pump Membrane transporter/Ion channel
Vonoprazan Fumarate (TAK438) 是质子泵的有效抑制剂,是口服有效的高效钾竞争性酸阻断剂,具有抗分泌活性。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50为 19 nM。它被开发用于研究酸相关疾病,如消化性溃疡和胃食管反流病。
T7615 Xenopsin

爪蟾肽,Xenopsin(2TFA)

Others Others
Xenopsin (Xenopsin(2TFA)) 是一种神经降压素样八肽,来自于非洲爪蟾皮肤,能够抑制胃泌素刺激的胃酸分泌。
T13145 Thiazolidinone-Derivatives-1

Others Others
Thiazolidinone-Derivatives-1 抑制胃酸分泌,可用于研究胃和十二指肠溃疡的治疗。
T1627 Famotidine

MK-208,法莫替丁

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Famotidine (MK-208) 是一种具有抗酸活性的丙脒和组胺 H2 受体拮抗剂。
TP1309 Gastric mucin

Antibacterial; Antibiotic Microbiology/Virology
Gastric mucin 是一种能保护胃肠道免受酸、蛋白酶、致病微生物和机械创伤影响的糖蛋白。
T0081 Lafutidine

拉呋替丁,FRG-8813

5-HT Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Lafutidine (FRG-8813) 是一种组胺受体 H2RA 拮抗剂,可抑制胃酸分泌,具有胃粘膜保护作用,可用于研究胃食管反流疾病。
T10221 Abeprazan hydrochloride

DWP14012 hydrochloride,Fexuprazan hydrochloride

Proton pump Membrane transporter/Ion channel
Abeprazan hydrochloride (Fexuprazan hydrochloride) 是一种有效的、可逆的、具有口服活性的potassium-competitive acid 阻滞剂,通过竞争性的与钾离子结合抑制 H+,K+- ATPase,而无需酸激活。Abeprazan hydrochloride 是一种质子泵抑制剂(PPI),通过减少胃酸的产生而起作用,可用于治疗胃酸相关疾病,如胃食管反流病(GERD)和消化性溃疡。
T20561L BPC 157 acetate(137525-51-0 free base)

BPC157 acetate,BPC-157 acetate,Bpc 15 acetate,Bpc15 acetate,Bpc-15 acetate

Others Others
BPC 157 acetate(137525-51-0 free base) 是一种具有保肝作用的胃肽 (BPC) 的 15 个氨基酸片段。
T0157 Roxatidine Acetate hydrochloride

HOE 760,盐酸罗沙替丁醋酸酯,Roxatidine Acetate HCl

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Roxatidine Acetate hydrochloride (HOE 760) 是一种特异性和竞争性的组胺 H2 受体拮抗剂,能抑制胃酸分泌,可用于胃溃疡和十二指肠溃疡的研究。
TP2030L1 Gastrin I (human) acetate

Gastrin I (human) acetate(10047-33-3 free base),Gastrin-17 acetate,Little gastrin I acetate,胃膜素醋酸盐

cholecystokinin GPCR/G Protein
Gastrin I (human) acetate (Gastrin-17 acetate) 是在胃中产生的内源性肽,通过胆囊收缩素 2 (CCK2) 受体增加胃酸分泌。
T0797 Cimetidine

西米替汀,SKF-92334,西咪替丁

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Cimetidine (SKF-92334) 是一种可口服的可逆组胺H2受体拮抗剂,Ki 为 0.6 μM。它抑制胃酸分泌,以及胃蛋白酶和胃泌素的输出,具有抗癌和抗炎活性。
T6929 Pantoprazole sodium

Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc

Apoptosis; Others; Proton pump; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Others
Pantoprazole sodium (Pantecta) 是一种具有口服活性的质子泵抑制剂,是一种取代的苯并咪唑,是H+/K+-ATPase 抑制剂,IC50为 6.8 μM。它可以改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。
TP1705 Gastrin I (1-14), human

Others Others
Gastrin I (1-14), human 是人胃泌素 I 肽的 1-14 片段。其中Gastrin I 是内源性胃肠肽激素。Gastrin 是胃酸分泌的主要激素调节剂。
T68016 Spiroglumide

CR-2194

cholecystokinin GPCR/G Protein
Spiroglumide 是一种CCKB-胃泌素拮抗剂,能够抑制剂量依赖性五肽胃泌素诱导的酸分泌过多,其ID50为20.1(8.67-46.4)mg / kg,可用于探索胃泌素在调节人类胃酸分泌中的生理作用。
TP2018L GIP (human) acetate

GIP (human) acetate(100040-31-1 Free base)

IGF-1R Tyrosine Kinase/Adaptors
GIP (human) acetate 是葡萄糖依赖性胰岛素分泌的刺激剂和胃酸分泌的弱抑制剂。 GIP (human) acetate 在脂质代谢和肥胖的发展中起着至关重要的作用。
T37588L GIP (1-30) amide, porcine acetate

IGF-1R Tyrosine Kinase/Adaptors
GIP (1-30) amide, porcine acetate 是完全葡萄糖依赖性促胰岛素多肽 (GIP) 受体的激动剂。它可弱抑制胃酸分泌,强烈刺激胰岛素。
T1467 Acemetacin

阿西美辛,K-708,TVX 1322

COX Immunology/Inflammation; Neuroscience
Acemetacin (TVX 1322) 是一种非甾体抗炎类的化合物。
T22391 Omeprazole Sodium

P450; Proton pump; Antibacterial; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Omeprazole 是有效的质子泵抑制剂,在胃肠道疾病的研究中具有价值。它竞争性抑制CYP2C19活性,Ki 为 2 到 6 μM。它还抑制革兰氏阴性菌和革兰氏阳性菌生长。它是中性鞘磷脂酶的外泌体抑制剂。
T2686 Esomeprazole Magnesium

(S)-Omeprazole magnesium,NEXIUM,埃索美拉唑镁,(-)-Omeprazole magnesium

ATPase; Proton pump Membrane transporter/Ion channel
Esomeprazole Magnesium (NEXIUM) 是一种口服有效的 H+, K+-ATPase 抑制剂,在上消化道疾病和胃食管反流疾病中具有研究价值。Esomeprazole magnesium 是一种外泌体抑制剂,通过抑制 V-H+-ATPases 来阻断外泌体的释放。
T16865 SCH28080

ATPase; Proton pump Membrane transporter/Ion channel
SCH28080 是一种可逆且具有 K+ 竞争性的胃 H+/K+-ATP 酶 (H+/K+-ATPase) 抑制剂,IC50 值为 20 nM (家兔微粒体膜)。SCH28080 在体内是有效的酸分泌抑制剂,具有抗溃疡活性、抗分泌和细胞保护活性。
T21385 Cinitapride

西尼必利,Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove

5-HT Receptor GPCR/G Protein; Neuroscience
Cinitapride (Blaston) 是一种促胃药。它减缓肌肉的活动,以减轻诸如胃酸反流、胃排空延迟和溃疡性消化不良等病症的症状。 Cinitapride 作为 5-HT2 受体的拮抗剂和 5-HT1 和 5-HT4 受体的激动剂。
TP1325L Gastrin-Releasing Peptide, human(TFA)

Others Others
Gastrin-Releasing Peptide, human(TFA) (93755-85-2 free base) 是一种调节性人类肽,可引发胃泌素释放并调节胃酸分泌和肠道运动功能。支配胃G 细胞的迷走神经节后纤维释放GRP,刺激G 细胞释放胃泌素。
T77599 Methyl retinoate

Retinoic acid, methyl ester

Others Others
Methyl retinoate (Retinoic acid, methyl ester) 在体内实验中会诱导给部位发生无菌炎症,会使血液中白细胞数量增加,而红细胞和Hb含量减少。Methyl retinoate 可促进自发性白血病的产生。Methyl retinoate 可用于治疗因维生素A缺乏而产生的胃肥大和溃疡。
T1083L Theophylline monohydrate

Quibron,茶碱一水合物

HDAC; PDE; Adenosine Receptor Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Theophylline monohydrate (Quibron) 似乎抑制磷酸二酯酶和前列腺素的产生,调节钙通量和细胞内钙分布,并拮抗腺苷。茶碱是黄嘌呤的天然生物碱衍生物,从植物山茶花和小粒咖啡中分离出来。在生理上,该药剂可放松支气管平滑肌,产生血管舒张(脑血管除外),刺激中枢神经系统,刺激心肌,利尿,增加胃酸分泌;它还可以抑制炎症并改善横膈膜的收缩性。
T31958 Glycine-pentagastrin

Glycine pentagastrin,Boc-gly-trp-met-asp-phe-NH2,Tbgtmap

Others Others
Glycine-pentagastrin can enhance gastric mucosal defence mechanisms against acid and protect the gastric mucosa from experimental injury.
T27669 JNJ-26070109

JNJ26070109

Others Others
JNJ-26070109, an antagonist of cholecystokinin CCK2 receptor, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.
T27092 CS-526

R-105266,R 105266,R105266

Others Others
CS-526 is a proton pump inhibitor. The inhibitory mechanism of CS-526 on H+,K+-ATPase was a competitive antagonism to the K+ binding site of H+,K+-ATPase, and it was also a reversible inhibition. CS-526 has a potent antisecretory effect on gastric acid se
T15005 CP-66948

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
CP-66948 是一种有效的 histamine H2 受体拮抗剂,对胃酸分泌有抑制作用,可用于保护胃黏膜和肠粘膜。
T69805 AU-006

Others Others
AU-006 is an anti-ulcer drug which is effective in the treatment of gastric ulcers by inhibiting gastric acid secretion.
T69164 Dibenamine

Others Others
Dibenamine is an alpha adrenergic antagonist that blocks basal and histamine-stimulated gastric acid secretion.
T20561 BPC 157

BPC-157,Booly protection compound 15,Bpc-15,Bpc15,BPC157,Bpc 15

BPC 157 is a 15-amino acid fragment of a gastric peptide (BPC) which has hepatoprotective effects.
T20660 Revaprazan

SB-641257,SB 641257,SB641257

Others Others
Revaprazan is a novel, selective potassium-competitive acid blocker, to be specific, it reversibly inhibits gastric H(+)/K(+)-ATPase and shows effective acid suppression comparable to PPIs.
T26090 Rioprostil

TR 4698,TR4698,Rioprostilum,TR-4698

Others Others
Rioprostil is a methyl prostaglandin E1 analog that decreases gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the treatment of gastric ulcers and gives significant protection against NSAID-induced gastric muco
T32224 Isopropamide

Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid

Others Others
Isopropamide (R5) is a long-acting anticholinergic drug. It is used to treat peptic ulcers and other gastrointestinal disorders involving excess gastric acid (gastrointestinal acidosis) and hyperactivity.
T30250 AZD0865

AZD-0865,AZD 0865

Others Others
AZD0865 is an effective drug that inhibits gastric H(+), K(+) -ATPase activity and acid formation in vitro, with rapid onset.
T13261 CCK-B Receptor Antagonist 1

Others Others
CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor agonist and has the potential of reducing the secretion of gastric acid.
T15722 Lavoltidine

Loxtidine,AH-234844

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Lavoltidine is an orally active and irreversible histamine H2-receptor antagonist. Lavoltidine strongly suppresses gastric acid secretion and also induces hypergastrinemia.

化合物

Tegoprazan
Cat.No: T17030
Synonym:
Target: ATPase, Proton pump
Linaprazan glurate
Cat.No: T38612
Synonym:
Target: Others
Pentagastrin
Cat.No: T4579
Synonym: 五肽胃泌素,ICI-50123
Target: Others, cholecystokinin
Dimaprit dihydrochloride
Cat.No: T22724
Synonym:
Target: NOS, NO Synthase, Histamine Receptor
Anisotropine Methylbromide
Cat.No: T4981
Synonym:
Target: Prostaglandin Receptor, AChR
Salsalate
Cat.No: T0498
Synonym: Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171,双水杨酸酯
Target: Reactive Oxygen Species, COX
Orlistat
Cat.No: T0686
Synonym: Ro-18-0647,奥利司他,Tetrahydrolipstatin
Target: Apoptosis, Others, Fatty Acid Synthase
Tenatoprazole
Cat.No: T6700
Synonym: 泰妥拉唑,TU-199
Target: Proton pump
Betazole dihydrochloride
Cat.No: T8599
Synonym: 盐酸倍他唑,Betazole hydrochloride
Target: Histamine Receptor
Ilaprazole
Cat.No: T1756L
Synonym: IY81149,艾普拉唑,IY 81149,IY-81149
Target: Proton pump, TOPK
Ilaprazole sodium
Cat.No: T1756
Synonym: IY-81149 sodium,艾普拉唑钠
Target: Proton pump, TOPK
Lansoprazole
Cat.No: T0674
Synonym: 兰索拉唑,A-65006,AG-1749
Target: Proton pump, Phospholipase, Antibacterial
Vonoprazan
Cat.No: T8388
Synonym: TAK-438 (free base),沃诺拉赞
Target: Proton pump
Vonoprazan Fumarate
Cat.No: T21254
Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞
Target: Proton pump
Xenopsin
Cat.No: T7615
Synonym: 爪蟾肽,Xenopsin(2TFA)
Target: Others
Thiazolidinone-Derivatives-1
Cat.No: T13145
Synonym:
Target: Others
Famotidine
Cat.No: T1627
Synonym: MK-208,法莫替丁
Target: Histamine Receptor
Gastric mucin
Cat.No: TP1309
Synonym:
Target: Antibacterial, Antibiotic
Lafutidine
Cat.No: T0081
Synonym: 拉呋替丁,FRG-8813
Target: 5-HT Receptor, Histamine Receptor
Abeprazan hydrochloride
Cat.No: T10221
Synonym: DWP14012 hydrochloride,Fexuprazan hydrochloride
Target: Proton pump
BPC 157 acetate(137525-51-0 free base)
Cat.No: T20561L
Synonym: BPC157 acetate,BPC-157 acetate,Bpc 15 acetate,Bpc15 acetate,Bpc-15 acetate
Target: Others
Roxatidine Acetate hydrochloride
Cat.No: T0157
Synonym: HOE 760,盐酸罗沙替丁醋酸酯,Roxatidine Acetate HCl
Target: Histamine Receptor
Gastrin I (human) acetate
Cat.No: TP2030L1
Synonym: Gastrin I (human) acetate(10047-33-3 free base),Gastrin-17 acetate,Little gastrin I acetate,胃膜素醋酸盐
Target: cholecystokinin
Cimetidine
Cat.No: T0797
Synonym: 西米替汀,SKF-92334,西咪替丁
Target: Histamine Receptor
Pantoprazole sodium
Cat.No: T6929
Synonym: Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc
Target: Apoptosis, Others, Proton pump, HIF, Autophagy
Gastrin I (1-14), human
Cat.No: TP1705
Synonym:
Target: Others
Spiroglumide
Cat.No: T68016
Synonym: CR-2194
Target: cholecystokinin
GIP (human) acetate
Cat.No: TP2018L
Synonym: GIP (human) acetate(100040-31-1 Free base)
Target: IGF-1R
GIP (1-30) amide, porcine acetate
Cat.No: T37588L
Synonym:
Target: IGF-1R
Acemetacin
Cat.No: T1467
Synonym: 阿西美辛,K-708,TVX 1322
Target: COX
Omeprazole Sodium
Cat.No: T22391
Synonym:
Target: P450, Proton pump, Antibacterial, Autophagy
Esomeprazole Magnesium
Cat.No: T2686
Synonym: (S)-Omeprazole magnesium,NEXIUM,埃索美拉唑镁,(-)-Omeprazole magnesium
Target: ATPase, Proton pump
SCH28080
Cat.No: T16865
Synonym:
Target: ATPase, Proton pump
Cinitapride
Cat.No: T21385
Synonym: 西尼必利,Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove
Target: 5-HT Receptor
Gastrin-Releasing Peptide, human(TFA)
Cat.No: TP1325L
Synonym:
Target: Others
Methyl retinoate
Cat.No: T77599
Synonym: Retinoic acid, methyl ester
Target: Others
Theophylline monohydrate
Cat.No: T1083L
Synonym: Quibron,茶碱一水合物
Target: HDAC, PDE, Adenosine Receptor
Glycine-pentagastrin
Cat.No: T31958
Synonym: Glycine pentagastrin,Boc-gly-trp-met-asp-phe-NH2,Tbgtmap
Target: Others
JNJ-26070109
Cat.No: T27669
Synonym: JNJ26070109
Target: Others
CS-526
Cat.No: T27092
Synonym: R-105266,R 105266,R105266
Target: Others
CP-66948
Cat.No: T15005
Synonym:
Target: Histamine Receptor
AU-006
Cat.No: T69805
Synonym:
Target: Others
Dibenamine
Cat.No: T69164
Synonym:
Target: Others
BPC 157
Cat.No: T20561
Synonym: BPC-157,Booly protection compound 15,Bpc-15,Bpc15,BPC157,Bpc 15
Target:
Revaprazan
Cat.No: T20660
Synonym: SB-641257,SB 641257,SB641257
Target: Others
Rioprostil
Cat.No: T26090
Synonym: TR 4698,TR4698,Rioprostilum,TR-4698
Target: Others
Isopropamide
Cat.No: T32224
Synonym: Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid
Target: Others
AZD0865
Cat.No: T30250
Synonym: AZD-0865,AZD 0865
Target: Others
CCK-B Receptor Antagonist 1
Cat.No: T13261
Synonym:
Target: Others
Lavoltidine
Cat.No: T15722
Synonym: Loxtidine,AH-234844
Target: Histamine Receptor
Cat. No. Product Name Target Signaling Pathways
T3727 Methyl syringate

Syringic Acid Methyl Ester,丁香酸甲酯

TRP/TRPV Channel Membrane transporter/Ion channel
Methyl syringate (Syringic Acid Methyl Ester) 是水仙花蜜的化学标记物,是有效的细菌和真菌漆酶酚介质。它也是TRPA1激动剂。
T20604L Litorin acetate(55749-97-8 Free base)

Bombesin Receptor GPCR/G Protein
Litorin acetate 是一种两栖类铃蟾肽衍生物,是一种铃蟾肽受体激动剂。它刺激平滑肌收缩,刺激胃泌素、胃酸和胰腺分泌,抑制体内营养。
TN2601 12-O-Methylcarnosic acid

Reductase Endocrinology/Hormones; Metabolism
12-O-Methylcarnosic acid 是分离自小叶丹参的丙酮提取物的一种二萜肉桂酸,可抑制 5α-还原酶 (5α-reductase) 活性,IC50为 61.7 μM。它抑制 LNCaP 细胞的增殖。它具有抗微生物活性、抗氧化和抗癌活性。
T2A2532 L-Histidine

Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

Mitochondrial Metabolism; Endogenous Metabolite Metabolism
L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
T20604 Litorin

Others Others
Litorin, an amphibian bombesin peptide derivative, is found to suppress the nutriment, to stimulate the contraction of smooth muscle, to stimulate gastrin, gastric acid, and pancreatic secretion.
TN3740 Cyclocommunol

PAFR GPCR/G Protein
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation.

天然产物

Methyl syringate
Cat.No: T3727
Synonym: Syringic Acid Methyl Ester,丁香酸甲酯
Target: TRP/TRPV Channel
Litorin acetate(55749-97-8 Free base)
Cat.No: T20604L
Synonym:
Target: Bombesin Receptor
12-O-Methylcarnosic acid
Cat.No: TN2601
Synonym:
Target: Reductase
L-Histidine
Cat.No: T2A2532
Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine
Target: Mitochondrial Metabolism, Endogenous Metabolite
Litorin
Cat.No: T20604
Synonym:
Target: Others
Cyclocommunol
Cat.No: TN3740
Synonym:
Target: PAFR
Cat. No. Product Name Species Expression System
TMPJ-01079 TFF2 Protein, Mouse, Recombinant (His)

SP,Trefoil Factor 2,Spasmolytic polypeptide,Tff2,Sml1

Mouse HEK293 Cells
Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute a...
TMPJ-01078 TFF2 Protein, Human, Recombinant (His)

SP,TFF2,Spasmolytic Polypeptide,Spasmolysin,SML1,Trefoil Fac...

Human HEK293 Cells
Trefoil Factor 2 (TFF2) is a member of the trefoil family and contains two P-type (trefoil) domains. Members of this family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF2 is a secreted protein and specifically expressed in the stomach. TFF2 inhibits gastrointestinal motility and gastric acid secretion. TFF2 could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in ...
TMPH-02522 GHRL Protein, Mouse, Recombinant (His)

Motilin-related peptide,Growth hormone-releasing peptide,Gro...

Mouse E. coli
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. GHRL Protein, Mouse, Recombinant (His) is expressed in E. coli expre...
TMPJ-00701 Carbonic Anhydrase 11 Protein, Human, Recombinant (His)

Carbonic Anhydrase-Related Protein 2,CARP XI,CA11,CARP-2,Car...

Human HEK293 Cells
Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA11 is expressed abundantly in the brain with moder...
TMPJ-00529 FABP6 Protein, Human, Recombinant (His)

Ileal Lipid-Binding Protein,I-BABP,Intestinal Bile Acid<...

Human E. coli
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level)...
TMPY-01877 CA5A Protein, Human, Recombinant (His)

CA5,GS1-21A4.1,CA5AD,carbonic anhydrase VA, mitochondrial,CA...

Human E. coli
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospi...
TMPY-02277 Carbonic Anhydrase 7 Protein, Human, Recombinant (His)

CAVII,carbonic anhydrase VII

Human E. coli
Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, ...
TMPJ-01173 TFF3 Protein, Mouse, Recombinant (His)

Itf,Trefoil factor 3,Intestinal trefoil factor,mITF,Tff3

Mouse HEK293 Cells
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process called restitution. TFF comprises the gastric peptides (TFF1), spasmolytic peptide (TFF2), and the intestinal trefoil factor (TFF3). They have an important and necessary role in epithelial restitution within the gastrointestinal tract. Members of the trefoil family are characterized b...
TMPY-02133 Carbonic Anhydrase VB Protein, Human, Recombinant (His)

carbonic anhydrase VB, mitochondrial,CA-VB,MGC39962

Human E. coli
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological process...
TMPY-01761 Carbonic Anhydrase 3 Protein, Human, Recombinant (His)

carbonic anhydrase III,CAIII,Car3

Human E. coli
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Carbonic anhydrases (CAs) form a family of enzymes that catalyze the rapid conversion of carbon dioxide and water to bicarbonate an...
TMPY-01416 OLFM4 Protein, Human, Recombinant (His)

hGC-1,GC1,OLM4,bA209J19.1,GW112,olfactomedin 4,OlfD,hOLfD,UN...

Human HEK293 Cells
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed...

重组蛋白

TFF2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01079
Species: Mouse
Expression System: HEK293 Cells
TFF2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01078
Species: Human
Expression System: HEK293 Cells
GHRL Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02522
Species: Mouse
Expression System: E. coli
Carbonic Anhydrase 11 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00701
Species: Human
Expression System: HEK293 Cells
FABP6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00529
Species: Human
Expression System: E. coli
CA5A Protein, Human, Recombinant (His)
Cat.No: TMPY-01877
Species: Human
Expression System: E. coli
Carbonic Anhydrase 7 Protein, Human, Recombinant (His)
Cat.No: TMPY-02277
Species: Human
Expression System: E. coli
TFF3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01173
Species: Mouse
Expression System: HEK293 Cells
Carbonic Anhydrase VB Protein, Human, Recombinant (His)
Cat.No: TMPY-02133
Species: Human
Expression System: E. coli
Carbonic Anhydrase 3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01761
Species: Human
Expression System: E. coli
OLFM4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01416
Species: Human
Expression System: HEK293 Cells
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