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39

抑制剂 & 化合物

11

天然产物

13

重组蛋白

5

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T83679 Parasin I (catfish) TFA

Parasin I是来自鲶鱼(P. asotus)组蛋白H2A N端区域的一种抗微生物肽片段,参与宿主防御。它通过在受伤P. asotus的皮肤黏膜中的cathepsin D从组蛋白H2A形成。Parasin I对多种革兰氏阳性和阴性细菌以及真菌具有活性(MICs分别为1-2, 1-4, 和1-2 µg/ml)。
T83666 Kisspeptin-10 (zebrafish) TFA

Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2,Kp-10

Kisspeptin-10是一种在斑马鱼的大脑、卵巢和睾丸中表达的神经肽,参与性腺发育和类固醇表达。在10 ng/ml的浓度下使用时,能提高孤立的斑马鱼卵巢滤泡中编码黄体生成素(luteinizing hormone, Lh)受体,以及孕酮受体a (Progestin receptor a, Pra)和Prb的mRNA水平。在0.1和1 µg/g的剂量下给予时,Kisspeptin-10能在雌性金鱼中增加黄体生成素的血清水平,但在雄性金鱼中则不会。
T20812 Azamethiphos

甲基吡啶磷,唑啶磷

AChE Neuroscience
Azamethiphos 是有机磷杀虫剂和神经毒性物质,能够抑制乙酰胆碱酯酶的活性。
T7556 Fadrozole hydrochloride

CGS 16949A,盐酸法倔唑

Aromatase Endocrinology/Hormones
Fadrozole hydrochloride (CGS 16949A) 是一种选择性的、有效,和非甾体类的芳香化酶抑制剂(IC50:6.4 nM)。
T0305 Erythrosine B

Erythrosine I,Erythrosin extra bluish,Erythrosin B,赤藓红B

Others Others
Erythrosine B (Erythrosine I) 是一种已被用于开发动物模型的新型光敏剂,在食品和纺织工业的人造染料中具有广泛的应用。
T21483 Tricaine methanesulfonate

3-氨基苯甲酸乙酯甲基磺酸盐,MS-222

Others Others
Tricaine methanesulfonate (MS-222) 常用于固定鱼的标记和运输,并能抑制入侵过程中的感觉系统。
T0578 Erythrosin B

Iodeosin,Tetraiodofluorescein,藻红B

Others Others
Erythrosin B (Iodeosin) 是一种四碘荧光素,在某些食物(樱桃、鱼)中用作红色色素,用作某些细胞类型的染色剂,以及用作牙菌斑的披露物。其分子结构与甲状腺素相似。
T14186 17-ODYA

17-十八炔酸,Alkynyl Stearic Acid

Others; PROTAC Linker Others; PROTAC
Alkynyl Stearic Acid 是 CYP450 ω-羟化酶抑制剂。它能够抑制与花生四烯酸孵育的大鼠肾皮质微粒体形成 20-HETE 、dihydroxyeicosatrienoic acids、epoxyeicosatrienoic acids。它可以改善异丙肾上腺素诱导的培养心肌细胞凋亡和坏死。
T37514 Hydroxy Dimetridazole

Drug Metabolite Metabolism
Hydroxy Dimetridazole 是Dimetridazol 的羟基化代谢产物。Dimetridazol 是一种硝基咪唑类药物,可用于对抗原生动物感染。
T31931 Gizzerosine

Others Others
Gizzerosine exists in the overheated fish meal that causes gizzard erosion in chicks.
T84967 11(Z)-Docosenoic Acid

Cetoleic Acid

Others Others
11(Z)-Docosenoic acid, a 22-carbon monounsaturated fatty acid, is identified in fish oil.
T34563 Scaritoxin

Others Others
Scaritoxin is a potent toxic substance isolated from poisonous fish.
T13866 Retinyl glucoside

Retinyl β-D-glucoside

Others Others
Retinyl-β-D-glucoside is a naturally occurring and biologically active metabolites of vitamin A, and are found in fish and mammals.
T35620 Ethoxyquin Dimer

Others Others
Ethoxyquin dimer is an antioxidant and metabolite of ethoxyquin .1 It prevents oxidation of polyunsaturated fatty acids in fish meal and fish oil. Dietary administration of ethoxyquin dimer (0.1, 0.3, and 0.5% w/w) induces microvesicular steatosis and hepatocyte necrosis, as well as increases liver levels of oxidized glutathione and total lipids in mice.2
T30173 Aspartyllysine

Asp-lys

Others Others
Aspartyllysine is a hydrophilic dipeptide widely distributed in nature. It is present in wheat, fish, and other nutrients. It is excreted by the kidney-specific high-affinity H+/peptide cotransport system.
T85196 Docosapentaenoyl Chloride

Others Others
Docosapentaenoyl chloride, a more reactive derivative of the ω-3 fatty acid known as docosapentaenoic acid (DPA) found in fish oils, is an advanced substance stemming from its free fatty acid form.
T37990 15-keto Prostaglandin F1α

15-keto Prostaglandin F1α

Others Others
15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.
T84612 1-O-hexadecyl-2-Eicosapentaenoyl-sn-glycero-3-PC

1-O-hexadecyl-2-Eicosapenaenoyl-sn-glycero-3-phosphocholine

Others Others
"1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-PC is a compound that results from the incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, a process demonstrated in neutrophils from monkeys and humans consuming a diet rich in fish oils. Furthermore, it functions as a precursor for PAF C-16 synthesis via the remodeling pathway."
T76593 (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)

'(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)' 为一种GnRH类似物,主要用于诱导养殖鱼类排卵和/或产卵。
T39546 Fluorescein tyramide

Others Others
Fluorescein tyramide is a widely utilized green fluorescent reagent (λ abs : 494 nm; λ em : 517 nm), primarily employed for tyramide signal amplification (TSA) in low-abundance IHC, ICC, in situ hybridization (FISH), and flow cytometry (FCM) applications.
T80443 ω-Conotoxin MVIID

SNX-238

Calcium Channel Membrane transporter/Ion channel; Metabolism
ω-Conotoxin MVIID (SNX-238) 是芋螺肽,能抑制ω-Conotoxin-GVIA敏感的高阈值Ca2+电流于鱼类视网膜神经节细胞。
T85190 all-cis-4,7,10,13,16-Docosapentaenoic Acid ethyl ester

SFE 24:5,all-cis-4,7,10,13,16-DPA ethyl ester

Others Others
All-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester (all-cis-4,7,10,13,16-DPA ethyl ester) is a derivative of docosapentaenoic acid (DPA), an omega-3 fatty acid prevalent in fish oils. This ethyl ester form is commonly included in dietary supplements formulations to enhance omega-3 fatty acid intake.
T37532 Docosahexaenoyl Glycine

The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.
T74905 ODN 2007

Others Others
ODN 2007是一种B类CpG ODN(寡脱氧核苷酸),兼具Toll样受体(TLR)配体功能。作为免疫调节剂和疫苗佐剂,它能够增强哺乳动物、鱼类及人类的免疫反应。其序列为5'-TCGTCGTTGTCGTTTTGTCGTT-3'。
T37242 (±)5(6)-DiHETE

Others Others
Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils. EPA is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases. (±)5(6)-DiHETE is a possible metabolite produced from EPA following epoxidation of the α-5 double bond. The biological activity of (±)5(6)-DiHETE has not been documented.
T35681 MeIQx

Others Others
MeIQx (MeIQx) is a food-derived carcinogen that has been found in high temperature-cooked fish and meats.1It is activated by hydroxylation and subsequent O-acetylationviathe cytochrome P450 (CYP) isoform CYP1A2 and N-acetyltransferase 2, respectively, in UV5 cells expressing the human enzymes to a metabolite that reacts with DNA to form adducts.2MeIQx (200 and 400 ppm in the diet) induces tumor formation in rats.3
T85146 11-Hexadecenoic Acid

C16:1 (cis-11/trans-11) Fatty Acid

Others Others
11-Hexadecenoic acid, a monounsaturated fatty acid, comprises both 11-cis-hexadecenoic acid and 11-trans-hexadecenoic acid. These isoforms are present in ewe milk fat and their concentrations increase when the diet is supplemented with lipids from linseed, sunflower, olive, or fish oils. Additionally, 11-trans-hexadecenoic acid is found in intramuscular fat of both male and female foals. The product is a blend of the 11-cis and 11-trans forms. [Matreya, LLC. Catalog No. 1208]
T37634 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Others Others
Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).
T84397 Heneicosapentaenoic Acid ethyl ester

HPA ethyl ester

Others Others
Heneicosapentaenoic Acid (HPA), a 21:5 ω-3 fatty acid, is found in minute quantities in green algae and fish oils, resembling eicosapentaenoic acid (EPA) but with an added carbon on the carboxyl end, positioning the initial double bond at the Δ6 location. HPA serves as a tool for examining the impact of double bond positions within n-3 fatty acids, as it is incorporated into phospholipids and triacylglycerol in vivo as efficiently as EPA and docosahexaenoic acid (DHA), while significantly inhibi...
T37632 TFM

Others Others
TFM is a piscicide.1It is toxic to sea lamprey (P. marinus) with LC50values ranging from 1.97 to 2.11 and 2.05 to 2.21 mg/L for sac and swim-up fry, respectively, 1.6 to 2.45 mg/L for juveniles, and 1.6 to 1.63 mg/L for adults. It is also toxic to juvenile lake sturgeon (A. fulvescens) less than 100 mm in size but not to a variety of other fish species. TFM (50 μM) uncouples oxidative phosphorylation by 22 and 28% in isolated sea lamprey and rainbow trout (O. mykiss) liver, respectively.2Formula...
T84379 all-cis-4,7,10,13,16-Docosapentaenoic Acid methyl ester

all-Z-4,7,10,13,16-DPA methyl ester,all-cis-4,7,10,13,16-DPA methyl ester,Osbond Acid methyl ester

Others Others
All-cis-4,7,10,13,16-Docosapentaenoic acid (all-cis-4,7,10,13,16-DPA) methyl ester, also known as Osbond acid, is an isomer of DPA and a more lipid-soluble variant of the free acid, primarily found in fish oils as an ω-3, 22-carbon fatty acid. Despite being an ω-6 fatty acid synthesized through the elongation and desaturation of arachidonic acid, its levels can decrease due to fatty acid desaturase syndrome, potentially impacting development. Additionally, increased expression of hepatic elongat...
T80378 Tilapia piscidin 3

Tilapia piscidin 3 是具抗菌谱广的肽类化合物,有效对抗多种革兰氏阳性菌与阴性菌,其对 V. vulnificus 204、V. alginolyticus、S. agalactiae 819、E. faecalis BCRC 10066、S. agalactiae BCRC 10787 的最小抑菌浓度 (MIC) 分别为 2.44、2.44、9.78、19.55、0.61 μg/mL。同時,Tilapia piscidin 3 对鱼红细胞显示出溶血性。
T84469 Heneicosapentaenoic Acid methyl ester

HPA methyl ester

Others Others
Heneicosapentaenoic Acid (HPA) is a fatty acid found in small amounts in Bryopsis pennata Lamouroux green algae and fish oils, with a structure similar to eicosapentaenoic acid (EPA), but with an additional carbon at the carboxyl end, resulting in the first double bond being in the Δ6 position. HPA is important for researching the impact of double bond positions in n-3 fatty acids, as it integrates into phospholipids and triacylglycerol in vivo as effectively as EPA and docosahexaenoic acid (DHA...
T35437 (-)-Viriditoxin

Others Others
(-)-Viriditoxin is a mycotoxin originally isolated from A. viridinutans that has antibacterial and antiproliferative activity. It is active against methicillin-sensitive and -resistant S. aureus (MSSA and MRSA, respectively), tetracycline-sensitive and -resistant Staphylococcus, vancomycin-sensitive and -resistant Enterococcus, and penicillin-sensitive and -resistant S. pneumoniae (MICs = 2-32 μg/ml). (-)-Viriditoxin is also active against fish pathogens, including S. iniae and S. parauberis (MI...
T38208 Heneicosapentaenoic Acid

Others Others
Heneicosapentaenoic Acid (HPA) is a 21:5 ω-3 fatty acid present in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA) except elongated with one carbon on the carboxyl end, placing the first double bond in the δ6 position. HPA can be used to study the significance of the position of the double bonds in ω-3 fatty acids. It incorporates into phospholipids and into triacylglycerol in vivo with the same efficiency as EPA and...
T38127 pNPS-DHA

Others Others
pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1It inhibits degranulation of RBL-2H3 mast cells (IC50= 15 μM).pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice. 1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)
T83705 BING TFA

Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria

BING是一种来源于日本稻田鱼(O. laptipes)的抗菌肽,由液泡蛋白质分选相关蛋白13D样(Vps13D)衍生而来。对包括耐甲氧西林的金黄色葡萄球菌(MRSA; MICs = 4-64 µg/ml)在内的各种革兰氏阴性和革兰氏阳性细菌都有活性。与氨苄西林、阿莫西林和新霉素共同使用时,对抗铜绿假单胞菌(P. aeruginosa)表现出协同效应,并能抑制大肠杆菌(E. coli)对卡那霉素和氨苄西林的抗药性发展。在体内,BING提高了被鳗弧菌(E. tarda)感染的O. laptipes的生存率。
T35881 Resolvin E2

Others Others
Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in m...
T84836 Osbond acid

all-cis-4,7,10,13,16-Docosapentaenoic acid

Others Others
DPA (二十二碳五烯酸) 是一种含有22个碳原子的脂肪酸,主要来源于鱼油,占人体总血清不饱和脂肪酸的0.1%至1%,其含量可随膳食补充剂摄入增加而上升。all-cis-4,7,10,13,16-DPA(奥斯键酸)作为DPA的一种异构体,通过花生四烯酸的延伸和脱饱和生成的ω-6脂肪酸。在脂肪酸脱饱和酶综合征期间,all-cis-4,7,10,13,16-DPA的水平下降可能会干扰正常发育。在非酒精性脂肪性肝炎中,一种与肝细胞癌相关的癌前病症,超长脂肪酸蛋白6的肝脏表达增加,同时超长链脂肪酸水平上升,包括all-cis-4,7,10,13,16-DPA。

化合物

Parasin I (catfish) TFA
Cat.No: T83679
Synonym:
Target:
Kisspeptin-10 (zebrafish) TFA
Cat.No: T83666
Synonym: Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2,Kp-10
Target:
Azamethiphos
Cat.No: T20812
Synonym: 甲基吡啶磷,唑啶磷
Target: AChE
Fadrozole hydrochloride
Cat.No: T7556
Synonym: CGS 16949A,盐酸法倔唑
Target: Aromatase
Erythrosine B
Cat.No: T0305
Synonym: Erythrosine I,Erythrosin extra bluish,Erythrosin B,赤藓红B
Target: Others
Tricaine methanesulfonate
Cat.No: T21483
Synonym: 3-氨基苯甲酸乙酯甲基磺酸盐,MS-222
Target: Others
Erythrosin B
Cat.No: T0578
Synonym: Iodeosin,Tetraiodofluorescein,藻红B
Target: Others
17-ODYA
Cat.No: T14186
Synonym: 17-十八炔酸,Alkynyl Stearic Acid
Target: Others, PROTAC Linker
Hydroxy Dimetridazole
Cat.No: T37514
Synonym:
Target: Drug Metabolite
Gizzerosine
Cat.No: T31931
Synonym:
Target: Others
11(Z)-Docosenoic Acid
Cat.No: T84967
Synonym: Cetoleic Acid
Target: Others
Scaritoxin
Cat.No: T34563
Synonym:
Target: Others
Retinyl glucoside
Cat.No: T13866
Synonym: Retinyl β-D-glucoside
Target: Others
Ethoxyquin Dimer
Cat.No: T35620
Synonym:
Target: Others
Aspartyllysine
Cat.No: T30173
Synonym: Asp-lys
Target: Others
Docosapentaenoyl Chloride
Cat.No: T85196
Synonym:
Target: Others
15-keto Prostaglandin F1α
Cat.No: T37990
Synonym: 15-keto Prostaglandin F1α
Target: Others
1-O-hexadecyl-2-Eicosapentaenoyl-sn-glycero-3-PC
Cat.No: T84612
Synonym: 1-O-hexadecyl-2-Eicosapenaenoyl-sn-glycero-3-phosphocholine
Target: Others
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
Cat.No: T76593
Synonym:
Target:
Fluorescein tyramide
Cat.No: T39546
Synonym:
Target: Others
ω-Conotoxin MVIID
Cat.No: T80443
Synonym: SNX-238
Target: Calcium Channel
all-cis-4,7,10,13,16-Docosapentaenoic Acid ethyl ester
Cat.No: T85190
Synonym: SFE 24:5,all-cis-4,7,10,13,16-DPA ethyl ester
Target: Others
Docosahexaenoyl Glycine
Cat.No: T37532
Synonym:
Target:
ODN 2007
Cat.No: T74905
Synonym:
Target: Others
(±)5(6)-DiHETE
Cat.No: T37242
Synonym:
Target: Others
MeIQx
Cat.No: T35681
Synonym:
Target: Others
11-Hexadecenoic Acid
Cat.No: T85146
Synonym: C16:1 (cis-11/trans-11) Fatty Acid
Target: Others
17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
Cat.No: T37634
Synonym:
Target: Others
Heneicosapentaenoic Acid ethyl ester
Cat.No: T84397
Synonym: HPA ethyl ester
Target: Others
TFM
Cat.No: T37632
Synonym:
Target: Others
all-cis-4,7,10,13,16-Docosapentaenoic Acid methyl ester
Cat.No: T84379
Synonym: all-Z-4,7,10,13,16-DPA methyl ester,all-cis-4,7,10,13,16-DPA methyl ester,Osbond Acid methyl ester
Target: Others
Tilapia piscidin 3
Cat.No: T80378
Synonym:
Target:
Heneicosapentaenoic Acid methyl ester
Cat.No: T84469
Synonym: HPA methyl ester
Target: Others
(-)-Viriditoxin
Cat.No: T35437
Synonym:
Target: Others
Heneicosapentaenoic Acid
Cat.No: T38208
Synonym:
Target: Others
pNPS-DHA
Cat.No: T38127
Synonym:
Target: Others
BING TFA
Cat.No: T83705
Synonym: Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria
Target:
Resolvin E2
Cat.No: T35881
Synonym:
Target: Others
Osbond acid
Cat.No: T84836
Synonym: all-cis-4,7,10,13,16-Docosapentaenoic acid
Target: Others
Cat. No. Product Name Target Signaling Pathways
T5613 Squalane

角鲨烷,Dodecahydrosqualene,Perhydrosqualene

Others Others
Squalane 是某些鱼油 (尤其是鲨鱼肝油) 和某些植物油中存在的脂质。它具有抗癌,抗氧化作用,可用作皮肤保湿和润肤剂。
T19284 Dimethylmalonic acid

2,2-Dimethylmalonic acid

Endogenous Metabolite Metabolism
Dimethylmalonic acid(2,2-Dimethylmalonic acid) 是人血清中的短链二羧酸,可用于预防或延缓鱼肌动球蛋白在冷冻缓冲溶液(pH 7)中的变性。
T20091 Stearamide

Stearic acid amide,NSC 66462,NSC66462,NSC-66462

Stearamide(Stearic acid amide)是一种初级脂肪酸酰胺,具有细胞毒性和鱼类毒性,可用于增加纳米颗粒的性能。
T22291 Chitin

Chitin (From shrimp and crab shells)

Others Others
Chitin 是一种大型的结构多糖,存在于真菌的细胞壁、昆虫的外骨骼以及鱼类和无脊椎动物的某些坚硬结构中。
TJO2742 DL-Methionine

蛋氨酸,methionine,DL-蛋氨酸,Acimetion,Racemethionine

Parasite Microbiology/Virology
DL-Methionine (Acimetion) 存在于肉类、鱼类和奶制品中,是可用于动物的天然饲料,还可杀死马铃薯上的金线虫。它是一种含有硫的必需氨基酸,具有氧化应激防御作用。
T65269 L-Aspartic acid potasium salt

Aspartic acid potasium salt,Potassium L-aspartate

Others Others
L-aspartic acid potasium salt(VX-548) 是一种广泛存在于动植物体内的氨基酸。L-aspartic acid potasium salt驱动氮氧化物的产生,从而促进吞噬作用,有助于提高鱼类的成活率。L-aspartic acid potasium salt 可对抗生素产生刺激,刺激作用可能与参与天冬氨酸-4-半醛生物合成的前体有关。
T4775 Arachidic acid

eicosanoic acid,Icosanoic Acid,花生酸

Others; Endogenous Metabolite Metabolism; Others
Arachidic acid (Icosanoic Acid) 是一种存在于所有哺乳动物细胞中的长链脂肪酸,通常酯化为膜磷脂,是人体组织中丰富的多不饱和脂肪酸之一。
T2A2498 L-Lysine

Aminutrin,Lysine Acid,lysine,L-赖氨酸,赖氨酸

Virus Protease; Endogenous Metabolite; Antifection Metabolism; Microbiology/Virology
L-Lysine (Aminutrin) 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。
TN6872 Trypsin

Protease-activated Receptor GPCR/G Protein
Trypsin 是一种可从鱼类分离出的丝氨酸蛋白酶,可水解赖氨酸或精氨酸羧基侧蛋白质。Trypsin 具有抗炎活性,可通过 PDCoV 的 S 糖蛋白与 pAPN 的相互作用诱导 PDCoV 感染的细胞膜融合,可激活 PAR2 和 PAR4,促进细胞增殖和分化。Trypsin 可用于促进伤口愈合和研究神经源性炎症。
T3138 Astaxanthin

β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin,虾青素

Reactive Oxygen Species; PPAR DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB
Astaxanthin (trans-Astaxanthin) 是可从雨生红球藻等多种海洋生物中提取得到的红色类胡萝卜素,是过氧化物酶体增殖物活化受体γ 的调节剂,具有抗增殖、神经保护作用和抗炎活性。它是一种抗氧化剂,有用于癌症和心血管疾病的研究潜力,作为颜色添加剂用于动物食品中。
TN7535 Dihydrotetrodecamycin

Streptonolid A

Others Others
Dihydrotetrodecamycin, a fungal metabolite extracted from S. nashvillensis, exhibits antibacterial properties. It demonstrates activity against the fish-pathogenic bacterium P. piscicida.

天然产物

Squalane
Cat.No: T5613
Synonym: 角鲨烷,Dodecahydrosqualene,Perhydrosqualene
Target: Others
Dimethylmalonic acid
Cat.No: T19284
Synonym: 2,2-Dimethylmalonic acid
Target: Endogenous Metabolite
Stearamide
Cat.No: T20091
Synonym: Stearic acid amide,NSC 66462,NSC66462,NSC-66462
Target:
Chitin
Cat.No: T22291
Synonym: Chitin (From shrimp and crab shells)
Target: Others
DL-Methionine
Cat.No: TJO2742
Synonym: 蛋氨酸,methionine,DL-蛋氨酸,Acimetion,Racemethionine
Target: Parasite
L-Aspartic acid potasium salt
Cat.No: T65269
Synonym: Aspartic acid potasium salt,Potassium L-aspartate
Target: Others
Arachidic acid
Cat.No: T4775
Synonym: eicosanoic acid,Icosanoic Acid,花生酸
Target: Others, Endogenous Metabolite
L-Lysine
Cat.No: T2A2498
Synonym: Aminutrin,Lysine Acid,lysine,L-赖氨酸,赖氨酸
Target: Virus Protease, Endogenous Metabolite, Antifection
Trypsin
Cat.No: TN6872
Synonym:
Target: Protease-activated Receptor
Astaxanthin
Cat.No: T3138
Synonym: β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin,虾青素
Target: Reactive Oxygen Species, PPAR
Dihydrotetrodecamycin
Cat.No: TN7535
Synonym: Streptonolid A
Target: Others
Cat. No. Product Name Species Expression System
TMPH-03745 TNF-alpha Protein, Zebrafish, Recombinant (His)

Lymphotoxin-alpha,tnfa,Tumor necrosis factor ligand superfam...

Danio rerio (Zebrafish) E. coli
TNF-alpha Protein, Zebrafish, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.6 kDa and the accession number is Q08CQ3.
TMPY-03632 EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc)

EFNB2A,efnb2,id:ibd572

Danio rerio (zebrafish) HEK293 Cells
EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is O73874.
TMPY-03633 EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His)

efnb2,EFNB2A,id:ibd572

Danio rerio (zebrafish) HEK293 Cells
EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.3 kDa and the accession number is O73874.
TMPH-03744 IL-1 beta Protein, Zebrafish, Recombinant (His & Myc)

Interleukin-1,il1b

Danio rerio (Zebrafish) E. coli
IL-1 beta Protein, Zebrafish, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.9 kDa and the accession number is E6N152.
TMPH-03743 IL-1 beta Protein, Zebrafish, Recombinant (His)

il1b,Interleukin-1

Danio rerio (Zebrafish) E. coli
IL-1 beta Protein, Zebrafish, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is E6N152.
TMPY-03080 VEGF165 Protein, Danio rerio (zebrafish), Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Danio rerio (zebrafish) Baculovirus Insect Cells
VEGF165 Protein, Danio rerio (zebrafish), Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is O73682.
TMPY-03297 BMP-2 Protein, Danio rerio (zebrafish), Recombinant

bone morphogenetic protein 2

Danio rerio (zebrafish) E. coli
BMP-2 Protein, Danio rerio (zebrafish), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.2 kDa and the accession number is B3DI86.
TMPK-01395 TENM2 Protein, Human, Recombinant (His)

Ten-m2,KIAA1127,Teneurin-2,TNM2,ODZ2,Tenascin-M2,Ten-2

Human HEK293 Cells
Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control.
TMPJ-00517 WIF-1 Protein, Human, Recombinant (His)

Wnt Inhibitory Factor 1,WIF-1,WIF1

Human HEK293 Cells
Wnt Inhibitory Factor 1 (WIF1) is a secreted protein, which binds WNT proteins and inhibits their activities. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. is found to be present in fish, amphibia and mammals. WIF1 is a recurrent target in human salivary gland oncogenesis.WIF1 may be involved in mesoderm segmentation. WIF1 is a tumor suppress...
TMPJ-00606 Leptin Protein, Carassius auratus, Recombinant (His)

OB,Leptin,LEP,Obese Protein,OBS,Obesity Factor

Carassius auratus P. pastoris (Yeast)
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. In mammals, leptin is mainly produced by the adipose tissue and encodes body fat reserves, acting as a short-term satiety signal. In fish, the presence of a leptin-like peptide was first evidenced by immuno-cross-reactivity, and its existence was certainly demonstrated after the finding by synteny ...
TMPY-06864 GLP1R Protein, Human, Recombinant (His & Avi)

glucagon-like peptide 1 receptor

Human HEK293 Cells
Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like p...
TMPY-02849 WIF1 Protein, Mouse, Recombinant (His)

AW107799,WIF-1,WNT inhibitory factor 1

Mouse HEK293 Cells
WIF1, also known as WIF-1 and wnt inhibitory factor 1, is a secreted protein that binds WNT proteins and inhibits their activities. It contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 may be involved in mesoderm segmentation and can be detected in fish, amphibia and mammals. WIF-1 is a recurrent target in human salivary gland oncogenesis. Downre...
TMPY-06599 ATP1B4 Protein, Human, Recombinant (His)

ATPase, Na+/K+ transporting, β 4 polypeptide,ATPase, Na+/K+ ...

Human E. coli
ATP1B4 is a member of the X(+)/potassium ATPases subunit beta family. It is highly expressed in skeletal muscle and at a lower level in heart. ATP1B4 gene can be found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na, K-ATPase. In placental mammals, the encoded protein interacts with the ...

重组蛋白

TNF-alpha Protein, Zebrafish, Recombinant (His)
Cat.No: TMPH-03745
Species: Danio rerio (Zebrafish)
Expression System: E. coli
EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc)
Cat.No: TMPY-03632
Species: Danio rerio (zebrafish)
Expression System: HEK293 Cells
EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His)
Cat.No: TMPY-03633
Species: Danio rerio (zebrafish)
Expression System: HEK293 Cells
IL-1 beta Protein, Zebrafish, Recombinant (His & Myc)
Cat.No: TMPH-03744
Species: Danio rerio (Zebrafish)
Expression System: E. coli
IL-1 beta Protein, Zebrafish, Recombinant (His)
Cat.No: TMPH-03743
Species: Danio rerio (Zebrafish)
Expression System: E. coli
VEGF165 Protein, Danio rerio (zebrafish), Recombinant
Cat.No: TMPY-03080
Species: Danio rerio (zebrafish)
Expression System: Baculovirus Insect Cells
BMP-2 Protein, Danio rerio (zebrafish), Recombinant
Cat.No: TMPY-03297
Species: Danio rerio (zebrafish)
Expression System: E. coli
TENM2 Protein, Human, Recombinant (His)
Cat.No: TMPK-01395
Species: Human
Expression System: HEK293 Cells
WIF-1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00517
Species: Human
Expression System: HEK293 Cells
Leptin Protein, Carassius auratus, Recombinant (His)
Cat.No: TMPJ-00606
Species: Carassius auratus
Expression System: P. pastoris (Yeast)
GLP1R Protein, Human, Recombinant (His & Avi)
Cat.No: TMPY-06864
Species: Human
Expression System: HEK293 Cells
WIF1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02849
Species: Mouse
Expression System: HEK293 Cells
ATP1B4 Protein, Human, Recombinant (His)
Cat.No: TMPY-06599
Species: Human
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
TMIJ-0490 Azamethiphos-d6

Azamethiphos-d6 是 Azamethiphos 的氘代化合物。Azamethiphos 的 CAS 号为 35575-96-3。Azamethiphos 是有机磷杀虫剂和神经毒性物质,能够抑制乙酰胆碱酯酶的活性。
T71302 Norfluoxetine-d5 HCl

Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa...
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...
T35790 Palmitic acid-1,2,3,4-13C4

Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...

同位素标记化合物

Azamethiphos-d6
Cat.No: TMIJ-0490
Synonym:
Target:
Norfluoxetine-d5 HCl
Cat.No: T71302
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
Palmitic acid-1,2,3,4-13C4
Cat.No: T35790
Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
Target:
TargetMol Loading
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