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Search Results for " dystrophy "

Targets Recommended: PPAR

45

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T39516	Bocidelpar	PPAR	DNA Damage/DNA Repair; Metabolism
	Bocidelpar 是一种有效的过氧化物酶体增殖物激活受体 delta 调节剂，可改善杜兴肌营养不良肌肉细胞中的线粒体生物合成和功能。
T7837	SR8278	Others	Others
	SR8278 是竞争性核血红素受体REV-ERB 合成拮抗剂，能够抑制 REV-ERBα 转录活性(EC50:0.47 μM)。它可用于调节生物体内的代谢和研究生物节律。
T11553	Heptamidine dimethanesulfonate SBi4211 dimethanesulfonate	Others	Others
	Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) 是一种与喷他脒有关的、强效的钙结合蛋白 S100B 的抑制剂 (Kd=6.9 μM)，选择性地杀死表达 S100B 的黑素瘤细胞。它是有效的强直性肌营养不良 (DM) 研究工具。
T11861	LM11A-31 dihydrochloride	Others	Others
	LM11A-31 dihydrochloride 是一种具有高血脑屏障通透性的氨基酸衍生物，能阻断 p75 介导的细胞死亡。它是一种 p75NTR(神经营养蛋白受体 p75) 非肽调节剂，是口服有效的 proNGF 拮抗剂。它可以逆转中晚期的阿尔茨海默氏病小鼠模型中的胆碱能神经突营养不良。
T17217	Vamorolone 地塞米松EP杂质E,VBP15	Glucocorticoid Receptor; NF-κB	Endocrinology/Hormones; NF-κB
	Vamorolone (VBP15) 是一种首创的，具有口服活性的解离性类固醇 (dissociative steroidal) 抗炎药和膜稳定剂。它抑制 (NF-κB) 抑制作用，并降低了激素的影响。它改善肌营养不良，无副作用。
T3424	Ezutromid BMN 195,VOX-C1100,依珠曲米,SMT C1100	Others	Others
	Ezutromid (BMN 195) 是一种具有口服活性的、首创的苯并恶唑 utrophin 调节剂，EC50=0.91 μM。它抑制人肝微粒体 CYP1A2 酶活性，IC50=5.4 μM。它可用于 Duchenne 型肌营养不良症 (DMD) 的研究。
T15198	Edasalonexent CAT-1004	NF-κB	NF-κB
	Edasalonexent (CAT-1004) 是一种可口服的 NF-κB 抑制剂，可用于改善杜氏肌营养不良症。
T9821	ART-CHEM-BB B025267 2-(4-二乙基氨基苯基)-6-甲基-5-苯并三唑胺	Others	Others
	ART-CHEM-BB B025267 是 utrophin 生成的上调剂，EC50 为 1.8 μM，可用于治疗 Duchenne 肌营养不良症的研究。
T1805	Ataluren PTC124	CFTR; Autophagy	Autophagy; Membrane transporter/Ion channel
	Ataluren (PTC124) 是一种可口服的 CFTR-G542X 无义等位基因抑制剂。
T72073	AKOS037652256	Others	Others
	AKOS037652256可作为 TRPML 调节剂，可用于治疗如溶酶体积存病、肌肉萎缩症、与年龄相关的常见神经退行性疾病、氧化应激或活性氧(ROS)相关疾病以及衰老等与 TRPML 活性相关的疾病。
T72072	2-benzylsulfanyl-6-methoxy-4-methylquinazoline	ROS	Immunology/Inflammation
	2-benzylsulfanyl-6-methoxy-4-methylquinazoline 可作为TRPML 调节剂，可用于治疗与TRPML 活性相关的疾病，如溶酶体储存病、肌肉萎缩症、氧化应激或活性氧(ROS)相关疾病和衰老。
T15945	MA-0204	PPAR	DNA Damage/DNA Repair; Metabolism
	MA-0204 是一种高选择性，可口服的过氧化物酶体增殖物激活受体 δ (PPARδ) 调节剂，对于人，小鼠和大鼠 PPARδ 的 EC50分别为 0.4、7.9 和 10 nM。它有用于 Duchene 肌营养不良症 (DMD) 的研究潜力。
T21792	CGP 3466B maleate 马来酸CGP3466B,Omigapil (Maleate),Omigapil maleate	Apoptosis	Apoptosis
	CGP 3466B maleate (Omigapil maleate) 是一种口服有效的 GAPDH 亚硝基化抑制剂，可消除 Aβ1-42 诱导的小鼠 tau 乙酰化，记忆障碍和运动功能障碍，Omigapil maleate 具有研究阿尔茨海默症的潜力。Omigapil maleate (CGP3446B maleate) 是一种有效的凋亡 (apoptosis) 抑制剂。Omigapil maleate 可用于研究先天性肌营养不良 (CMD)。
T38554	Eteplirsen 依特立生；依特普森,AVI 4658	Others	Others
	Eteplirsen (AVI 4658) is a synthetic antisense oligonucleotide utilized in research for Duchenne muscular dystrophy.
T79918	α7β1 integrin modulator-1	Integrin	Cytoskeletal Signaling
	α7β1integrinmodulator-1，作为一种高效的α7β1integrin调节剂，展现出在肌营养不良症研究中的应用潜力。
T34425	RTC13 Read-through compound 13,RTC 13,RTC-13	Others	Others
	RTC13, as a premature termination codon (PTC) readthrough inducer, can act by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.
T13491	Neuromuscular-targeting compound 1	Others	Others
	Neuromuscular-targeting compound 1 可用于研究肌肉萎缩和神经肌肉相关疾病。
T39517	Suvodirsen WVE-210201	Others	Others
	Suvodirsen (WVE-210201) is an oligonucleotide compound with potential applications in the study of Duchenne muscular dystrophy (DMD).
T84750	Baliforsen ISIS-DMPK-2.5Rx,BIIB 065,IONIS 598769	Others	Others
	Baliforsen是一种由16个核苷酸组成的反义寡核苷酸，设计用于针对DMPK mRNA以研究强直性肌营养不良。
T34426	RTC14 Read-through compound-14,RTC 14,RTC-14,Read-through compound 14	Others	Others
	RTC14, as a premature termination codon (PTC) readthrough inducer, can act by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.
T61182	(R)-BDP9066	Others	Others
	(R)-BDP9066 is a highly effective inhibitor of myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK), effectively impeding cancer cell invasion, making it an invaluable resource for studying and researching proliferative diseases, particularly cancer.
T60594	OX01914	Others	Others
	OX01914 是一种水溶性和细胞膜可渗透的 utrophin 调节剂，能够上调 utrophin 蛋白水平，EC50值为 20.5 μM。 OX01914 可用于研究杜氏肌肉营养不良症(DMD)。
T38860	Golodirsen Golodirsen,SRP-4053	Others	Others
	Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) designed to selectively bind and target exon 53 of dystrophin pre-mRNA, with applications in the investigation of Duchenne muscular dystrophy (DMD).
T11553L	Heptamidine SBi4211	Others	Others
	Heptamidine is an effective Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM). It selectively kills melanoma cells with S100B over those without S100B. It is a useful tool for the investigation of Myotonic dystrophy.
T39455	Viltolarsen NS-065,NCNP-01	Others	Others
	Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide that specifically targets the splicing of exon 53 in the dystrophin gene. It is utilized in research related to Duchenne muscular dystrophy (DMD).
T21427	Mexiletine Mexitil,Mexiletene,KO-1173,KO1173,KO 1173	Others	Others
	Mexiletine is a non-selective voltage-gated sodium channel blocker. It is a medicine in the class of IB anti-arrhythmic. Mexiletine may also be used in patients experiencing refractory pain and is effective to treat muscle stiffness resulting from myotonic dystrophy or non-dystrophic myotonias.
T83175	Activated DPG Subunit	Others	Others
	Activated DPG Subunit 用于合成可诱导外显子 51 跳跃的外显子跳跃寡聚物偶联物。这些偶联物与人抗肌萎缩蛋白基因中选定的靶位点互补，有助于肌肉萎缩症的研究。
T61645	Utrophin modulator 1	Others	Others
	Utrophin Modulator 1 (UM1) is a highly effective agent that upregulates utrophin protein levels, displaying an EC 50 of 0.11 μM. Its application in the investigation of Duchenne Muscular Dystrophy (DMD) has been well-established [1].
T66481	TG-693	Others	Others
	TG693, an orally available inhibitor of CLK1, promotes the skipping of the endogenous mutated exon 31 in Duchenne muscular dystrophy (DMD) patient-derived cells and increased the production of the functional exon 31-skipped dystrophin protein.
T14129	Adenylosuccinic acid Aspartyl adenylate,Adenylosuccinate	Others	Others
	Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD)[1] and can be co
T83177	Activated A Subunit	Others	Others
	Activated A Subunit 适用于合成促进外显子跳跃的寡聚物偶联体。所合成的偶联体与人类抗肌萎缩蛋白基因内特定的序列配对互补，能够有效促进外显子51的跳跃，为肌萎缩疾病研究提供了一种工具。
T33595	Naproxcinod AZD3582,Nitronaproxen,AZD-3582,Naproxen-N-butyl nitrate,HCT3012,AZD 3582	Others	Others
	Naproxcinod, a nitric oxide-releasing NSAID derivative, significantly improved skeletal muscle strength and fatigue resistance in sedentary and exercise mice, reducing inflammatory infiltration and fibrotic deposition in the myocardium and diaphragm. In a
T82222	H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
	H-D-MeAla-EtVal-Val-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe 是一种非免疫抑制性的环孢菌素A衍生物，具备研究先天性肌营养不良症潜力[1]。
T83176	Activated C Subunit	Others	Others
	Activated C Subunit 用于合成可诱导外显子51跳跃的外显子跳跃寡聚物偶联物。所得寡聚物偶联物与人类抗肌萎缩蛋白基因特定靶位点互补，有助于研究肌肉萎缩症。
T73321	CLK1-IN-2	Others	Others
	CLK1-IN-2 是代谢稳定的Clk1抑制剂。CLK1-IN-2 对 Clk1 具有选择性，IC50值为 1.7 nM。CLK1-IN-2 可用于肿瘤、杜氏肌营养不良症和病毒感染如HIV-1和流感的研究。
T38859	Casimersen SRP-4045	Others	Others
	Casimersen (SRP-4045) is an antisense oligonucleotide, specifically belonging to the phosphorodiamidate morpholino oligomer subclass. It binds to exon 45 of dystrophin pre-mRNA, effectively restoring the open-reading frame by skipping exon 45. This action ultimately leads to the production of a functional dystrophin protein, albeit internally truncated. Casimersen finds utility in Duchenne muscular dystrophy (DMD) research.
T84749	Drisapersen Kyndrisa,GSK2402968A,PRO051	Others	Others
	Drisapersen是通过在dystrophin pre-mRNA剪接过程中诱导51号外显子跳跃，合成部分功能性dystrophin的反义寡核苷酸，主要用于杜氏肌营养不良症的研究。
T83174	Activated EG3 Tail	Others	Others
	Activated EG3 Tail 适用于合成外显子跳跃寡聚物偶联物。该寡聚物偶联物能与人类抗肌萎缩蛋白基因特定的靶位点匹配，进而诱导外显子 51 的跳跃。此类偶联物对于肌肉萎缩症研究具有重要价值。
T81693	NCP2 Anchor	Others	Others
	NCP2 Anchor用于合成外显子跳跃寡聚物偶联物。它的偶联物与人抗肌萎缩蛋白基因特定靶位点配对互补，从而诱导外显子52的跳跃。该偶联物常应用于肌肉萎缩症的科学研究。
T83173	Activated T Subunit	Others	Others
	Activated T Subunit 用于合成可诱导外显子51跳跃的外显子跳跃寡聚物偶联物。该寡聚物偶联物与人类抗肌萎缩蛋白基因中选定靶位点互补，适用于肌肉萎缩症研究。
T74699	Avacincaptad pegol	Others	Others
	Avacincaptad pegol 是核酸适配体，作为 C5 补体抑制剂，用以减轻炎症导致的视网膜色素上皮 (RPE) 损伤。该化合物可用于研究 stargardt 黄斑营养不良 (STGD1) 与地理萎缩 (GA)。
T37449	SR 12460	Others	Others
	SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-κB essential modulator (NEMO/IKKγ) and IKKβ.1It inhibits TNF-α-induced NF-κB activation in a reporter assay when used at concentrations ranging from 25 to 150 μM. It reduces LPS-induced production of IL-6 in RAW 264.7 cells. SR 12460 (30 mg/kg) improves grip strength in themdxmouse model of Duchenne muscular dystrophy. 1.Zhao, J., Zhang...
T73919	Adenylosuccinic acid tetraammonium	Others	Others
	Adenylosuccinic acid tetraammonium（Adenylosuccinate; Aspartyl adenylate）是一种在核苷酸循环代谢中起作用的口服活性嘌呤核糖核苷单磷酸。该化合物可通过腺苷琥珀酸裂解酶转化为富马酸，展现出在杜氏肌营养不良症（DMD）研究中的应用潜力。
T75137	BAY-747	Others	Others
	BAY-747 (BAY 1165747) 为一种通过口服生效且具有脑渗透性的sGC刺激剂。它能可逆地逆转L-NAME所诱导的记忆障碍并在大鼠中增强认知功能。BAY-747还可在有意识状态下降低正常血压及自发性高血压大鼠(SHR)的血压。此外，BAY-747在mdx/mTRG2小鼠模型中改善了与Duchenne肌营养不良症(DMD)相关的骨骼肌功能。
T38187	6-Aminophenanthridine	Others	Others
	6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz . 6-Aminophenanthridine (300 μM) inhibits protein folding activity of the ribosome (PFAR) by directly competing with protein substrates for the active site and decreases the yield of refolded protein without affecting the refolding rate. It prevents progressive w...

化合物

Cat.No: T39516

Target: PPAR

Cat.No: T7837

Target: Others

Heptamidine dimethanesulfonate

Cat.No: T11553

Synonym: SBi4211 dimethanesulfonate

Target: Others

LM11A-31 dihydrochloride

Cat.No: T11861

Target: Others

Cat.No: T17217

Synonym: 地塞米松EP杂质E,VBP15

Target: Glucocorticoid Receptor, NF-κB

Cat.No: T3424

Synonym: BMN 195,VOX-C1100,依珠曲米,SMT C1100

Target: Others

Cat.No: T15198

Synonym: CAT-1004

Target: NF-κB

ART-CHEM-BB B025267

Cat.No: T9821

Synonym: 2-(4-二乙基氨基苯基)-6-甲基-5-苯并三唑胺

Target: Others

Cat.No: T1805

Synonym: PTC124

Target: CFTR, Autophagy

Cat.No: T72073

Target: Others

2-benzylsulfanyl-6-methoxy-4-methylquinazoline

Cat.No: T72072

Target: ROS

Cat.No: T15945

Target: PPAR

CGP 3466B maleate

Cat.No: T21792

Synonym: 马来酸CGP3466B,Omigapil (Maleate),Omigapil maleate

Target: Apoptosis

Cat.No: T38554

Synonym: 依特立生；依特普森,AVI 4658

Target: Others

α7β1 integrin modulator-1

Cat.No: T79918

Target: Integrin

Cat.No: T34425

Synonym: Read-through compound 13,RTC 13,RTC-13

Target: Others

Neuromuscular-targeting compound 1

Cat.No: T13491

Target: Others

Cat.No: T39517

Synonym: WVE-210201

Target: Others

Cat.No: T84750

Synonym: ISIS-DMPK-2.5Rx,BIIB 065,IONIS 598769

Target: Others

Cat.No: T34426

Synonym: Read-through compound-14,RTC 14,RTC-14,Read-through compound 14

Target: Others

Cat.No: T61182

Target: Others

Cat.No: T60594

Target: Others

Cat.No: T38860

Synonym: Golodirsen,SRP-4053

Target: Others

Cat.No: T11553L

Synonym: SBi4211

Target: Others

Cat.No: T39455

Synonym: NS-065,NCNP-01

Target: Others

Cat.No: T21427

Synonym: Mexitil,Mexiletene,KO-1173,KO1173,KO 1173

Target: Others

Activated DPG Subunit

Cat.No: T83175

Target: Others

Utrophin modulator 1

Cat.No: T61645

Target: Others

Cat.No: T66481

Target: Others

Adenylosuccinic acid

Cat.No: T14129

Synonym: Aspartyl adenylate,Adenylosuccinate

Target: Others

Activated A Subunit

Cat.No: T83177

Target: Others

Cat.No: T33595

Synonym: AZD3582,Nitronaproxen,AZD-3582,Naproxen-N-butyl nitrate,HCT3012,AZD 3582

Target: Others

H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe

Cat.No: T82222

Activated C Subunit

Cat.No: T83176

Target: Others

Cat.No: T73321

Target: Others

Cat.No: T38859

Synonym: SRP-4045

Target: Others

Cat.No: T84749

Synonym: Kyndrisa,GSK2402968A,PRO051

Target: Others

Activated EG3 Tail

Cat.No: T83174

Target: Others

Cat.No: T81693

Target: Others

Activated T Subunit

Cat.No: T83173

Target: Others

Avacincaptad pegol

Cat.No: T74699

Target: Others

Cat.No: T37449

Target: Others

Adenylosuccinic acid tetraammonium

Cat.No: T73919

Target: Others

Cat.No: T75137

Target: Others

6-Aminophenanthridine

Cat.No: T38187

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02429	Fukutin Protein, Cynomolgus, Recombinant (His & Myc) FKTN,Fukutin,Fukuyama-type congenital muscular dystrophy...	Cynomolgus	E. coli
	Fukutin Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.0 kDa and the accession number is Q60HG0.
TMPH-02666	Fukutin Protein, Mouse, Recombinant (His & Myc) Fktn,Fukutin,Ribitol-5-phosphate transferase FKTN,Fukuyama-t...	Mouse	E. coli
	Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-b...
TMPY-01009	TGFBI Protein, Human, Recombinant (His) CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be...	Human	HEK293 Cells
	TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys...
TMPK-01376	TROP-2 Protein, Mouse, Recombinant (aa 25-270, His) TACD2,gp50,TACSTD2,M1S1,TROP-2,GA733-1,T16,EGP-1,EGP1,TROP2	Mouse	HEK293 Cells
	Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
TMPY-03833	TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (His) tetraspanin 7	Cynomolgus	HEK293 Cells
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4...
TMPY-03930	TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (mFc) tetraspanin 7	Cynomolgus	HEK293 Cells
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4...
TMPY-04559	CDC42BPB Protein, Human, Recombinant (His & GST) CDC42 binding protein kinase beta (DMPK-like),MRCKB,CDC42 bi...	Human	Baculovirus Insect Cells
	CDC42BPB is a member of the serine / threonine protein kinase family that contains a Cdc42 / Rsc-binding p21 binding domain similar to that of PAK kinase. The kinase domain of this protein is related to the myotonic dystrophy kinase related ROK and this kinase may have functions in downstream regulating of Cdc42 in cytoskeletal recognization. It has been reported that the CDC42BPB protein take part in regulating numerous cellular functions by binding to members of a serine / threonine protein ki...
TMPY-03871	TM4SF2/TSPAN7 Protein, Mouse, Recombinant (His) AI323365,Tm4sf2,PE31,A15,R74651,TALLA,Mxs1,Cd231,1200014P11R...	Mouse	HEK293 Cells
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4...
TMPJ-01251	POMGNT1 Protein, Human, Recombinant (His) 2-N-Acetylglucosaminyltransferase 1,UDP-GlcNAc:α-D-Mannoside...	Human	HEK293 Cells
	Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystr...
TMPY-00029	TM4SF2/TSPAN7 Protein, Rat, Recombinant (His) tetraspanin 7	Rat	HEK293 Cells
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4...
TMPY-03862	TM4SF2/TSPAN7 Protein, Human, Recombinant (His) TM4SF2,A15,MXS1,tetraspanin 7,TALLA-1,CCG-B7,CD231,DXS1692E,...	Human	HEK293 Cells
	TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TM4...
TMPY-03385	FKBP14 Protein, Human, Recombinant (His) IPBP12,EDSKMH,FK506 binding protein 14, 22 kDa,FKBP22	Human	HEK293 Cells
	FKBP14 belongs to the FK506-binding protein family. It contains 2 EF-hand domains and one PPIase FKBP-type domain. FKBP14 can be detected in the lumen of the endoplasmic reticulum where it is thought to accelerate the folding of proteins during protein synthesis. Truncation of the amino-terminus of FKBP14 significantly decreases peptidyl prolyl cis-trans isomerase activity, therefore implicating that the PPIase FKBP-type domain must be located at the N-terminus. Defects in FKBP14 can cause Ehler...

重组蛋白

Fukutin Protein, Cynomolgus, Recombinant (His & Myc)

Cat.No: TMPH-02429

Species: Cynomolgus

Expression System: E. coli

Fukutin Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02666

Species: Mouse

Expression System: E. coli

TGFBI Protein, Human, Recombinant (His)

Cat.No: TMPY-01009

Species: Human

Expression System: HEK293 Cells

TROP-2 Protein, Mouse, Recombinant (aa 25-270, His)

Cat.No: TMPK-01376

Species: Mouse

Expression System: HEK293 Cells

TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03833

Species: Cynomolgus

Expression System: HEK293 Cells

TM4SF2/TSPAN7 Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPY-03930

Species: Cynomolgus

Expression System: HEK293 Cells

CDC42BPB Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04559

Species: Human

Expression System: Baculovirus Insect Cells

TM4SF2/TSPAN7 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03871

Species: Mouse

Expression System: HEK293 Cells

POMGNT1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01251

Species: Human

Expression System: HEK293 Cells

TM4SF2/TSPAN7 Protein, Rat, Recombinant (His)

Cat.No: TMPY-00029

Species: Rat

Expression System: HEK293 Cells

TM4SF2/TSPAN7 Protein, Human, Recombinant (His)

Cat.No: TMPY-03862

Species: Human

Expression System: HEK293 Cells

FKBP14 Protein, Human, Recombinant (His)

Cat.No: TMPY-03385

Species: Human

Expression System: HEK293 Cells

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