30
3
15
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8615 |
ISOTHIAZOLINE 1,1-DIOXIDE
异噻唑烷 1,1-二氧化物,isothiazolidine 1,1-dioxide |
Others | Others |
ISOTHIAZOLINE 1,1-DIOXIDE (isothiazolidine 1,1-dioxide) 是一种反应物,用于合成口服生物可利用的 hebatits B caspid 抑制剂,并用于制备隐花色素抑制剂作为抗糖尿病药物。 | |||
T28754 |
Sepin-1
Sepin 1,Sepin1,2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide |
Others | Others |
Sepin-1 是一种分离酶的非竞争性抑制剂,IC50 为 14.8 µM。 Sepin-1可以通过抑制细胞增殖和诱导细胞凋亡来抑制小鼠和人类癌细胞系乳腺癌异种移植瘤的生长。 | |||
T16950 |
Sudoxicam
舒多昔康,4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide |
COX | Immunology/Inflammation; Neuroscience |
Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) 是一种可逆的 COX 拮抗剂,具有抗炎、抗水肿和解热特性。 | |||
T30743 |
Carbon dioxide reduction factor
Methanofuran,Cdr factor |
Others | Others |
Carbon dioxide reduction factor is a coenzyme of methanogenesis from carbon dioxide. | |||
T32615 |
L-Cystine S,S-dioxide
Cystinedisulfoxide |
Others | Others |
L-Cystine S,S-dioxide is a metabolite of L-Cystine. | |||
T34857 |
Thiophene-3-ol, 2,3-dihydro-, sulfate, 1,1-dioxide
|
Others | Others |
Thiophene-3-ol, 2,3-dihydro-, sulfate, 1,1-dioxide is a bioactive chemical. | |||
T60224 |
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
|
GluR | Neuroscience |
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-是S 18986的低活性异构体。S 18986是一种AMPA 受体阳性调节剂,EC2(浓度为AMPA 诱导电流强度的两倍)为35μM。 | |||
T73955 |
Potassium clavulanate mixture with silicon dioxide (1:1)
|
Others | Others |
Potassium clavulanate mixture with silicon dioxide (1:1)为Potassium clavulanate与Silicon dioxide按1:1比例混合而成的化合物。 | |||
T65943 |
Methyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
|
Others | Others |
Methyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65943。 | |||
T65688 |
Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
|
Others | Others |
Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65688,CAS号为 24683-26-9。 | |||
T65296 |
Methyl 4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxylate 1,1-dioxide
|
Others | Others |
Methyl 4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxylate 1,1-dioxide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65296,CAS号为 59804-25-0。 | |||
T65610 |
(S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
|
Others | Others |
(S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65610,CAS号为 154127-42-1。 | |||
T67423 |
Tazobactam diphenylmethyl ester
|
Others | Others |
Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67423。 | |||
T23478 |
Trometamol hydrochloride
TRIS hydrochloride,三(羟甲基)氨基甲烷盐酸盐 |
Others | Others |
Trometamol hydrochloride (TRIS hydrochloride) 是低毒性的生物惰性氨基醇,可以在体内、外缓冲二氧化碳和酸,能用于生理范围内控制 pH 值。 | |||
T2134 |
Dorzolamide hydrochloride
MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl |
Carbonic Anhydrase | Metabolism |
Dorzolamide hydrochloride (MK507 hydrochloride) 是一种碳酸酐酶carbonic anhydrase II 抑制剂,能够抑制红细胞CA-II(IC50:0.18 nM) 和CA-I(IC50:600 nM) 。 | |||
T39182 |
1-Bromo-1,1-dichloroacetone
|
Others | Others |
1-Bromo-1,1-dichloroacetone, classified as a chlorine dioxide disinfection byproduct (DBP), is present in drinking water. | |||
T10716 |
CCR7 Ligand 1
CCR7-Cmp2105 |
Others | Others |
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM | |||
T38945 |
Carboxy-PTIO
|
Others | Others |
Carboxy-PTIO is a highly effective nitric oxide (NO) scavenger known for its rapid reaction rate with NO, resulting in the formation of nitric dioxide (NO2). Its direct scavenging action against NO plays a crucial role in preventing hypotension and endotoxic shock, particularly in lipopolysaccharide-stimulated rat models. | |||
T78971 |
AMPA receptor modulator-4
|
iGluR | Membrane transporter/Ion channel; Neuroscience |
AMPA receptor modulator-4 是一种口服有效的 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD) 类 AMPA 受体正变构调节剂 (AMPAR PAM)。该化合物能穿透血脑屏障,能够增强小鼠的认知能力并改善其工作记忆。 | |||
T77233 |
L-Tartaric acid sodium hydrate
|
Others | Others |
L-Tartaric acid (L-(+)-Tartaric acid) sodium hydrate,D-酒石酸的对映异构体,是一种存在于多种植物(例如葡萄)中的白色结晶二羧酸,也是葡萄酒中的主要有机酸之一。此化合物能与碳酸氢钠反应生成二氧化碳,用作面粉膨松剂,同时也是食品添加剂。 | |||
T36512 |
PTIO
|
NO Synthase | Immunology/Inflammation |
PTIO 是一种特定的 NO 清除剂。 PTIO 与一氧化氮反应形成二氧化氮和相应的亚氨基氮氧化物。 PTIO 可用于检查一氧化氮合酶抑制活性。 | |||
T75327 |
Magnesium silicate
|
Others | Others |
Magnesium silicate (Activated magnesium silicate) 是由氧化镁 (MgO) 和二氧化硅 (SiO2) 组成的化合物。该化合物在制备抗酸剂和抗溃疡剂中应用,同时也作为除臭剂、脱色剂和抗真菌剂使用。 | |||
T76143 |
Pyruvate oxidase
|
Others | Others |
Pyruvate oxidase(PoxB) 是一种焦磷酸硫胺素依赖型的氧化酶,可以催化丙酮酸氧化脱羧生成乙酰磷酸、二氧化碳和水。Pyruvate oxidase 是细菌代谢中的一种重要酶,常用于生化研究。 | |||
T85026 |
9(E),11(E)-9-nitro Conjugated Linoleic Acid
9E,11E-9-nitro CLA |
Others | Others |
9(E),11(E)-9-nitro Conjugated Linoleic Acid (9E,11E-9-nitro CLA) is a nitrated fatty acid produced from 9Z,11E-CLA through exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or the combined action of myeloperoxidase, hydrogen peroxide, and nitrite. Additionally, it forms in LPS-stimulated RAW 264.7 macrophages, a process that can be inhibited by the nitric oxide synthase (NOS) inhibitor L-NAME. This compound has also been detected in human plasma. | |||
T76013 |
Carbonic anhydrase
|
Others | Others |
Carbonic anhydrase 是原核生物和真核生物中普遍存在的含锌金属酶。Carbonic anhydrase 可以催化二氧化碳可逆地转化为碳酸氢盐和质子。Carbonic anhydrase 可用于癌症、青光眼、肥胖症和癫痫症的研究。 | |||
T76149 |
Formate dehydrogenase
|
Others | Others |
Formate dehydrogenase 是一种普遍存在于原核生物和真核生物中的酶,能催化甲酸盐可逆氧化为二氧化碳。根据其金属含量、结构及催化策略,可将Formate dehydrogenase 分为非金属类和含金属类两种,广泛应用于生化研究领域。 | |||
T73614 |
Tyrosine decarboxylase
|
Others | Others |
Tyrosine decarboxylase (TDC; TyrDC),即酪氨酸脱羧酶,广泛存在于植物、昆虫和不同微生物中,常用于生化研究。Tyrosine decarboxylase 是一种5'-磷酸吡哆醛 (PLP) 依赖性脱羧酶,可以催化酪氨酸中羧基的去除,产生酪胺和二氧化碳。 | |||
T19902 |
C.I. 15670
NSC-12453,NSC12453,NSC 12453 |
||
C.I. 15670是一种颜料,为红紫色粉末。可用于油墨、染料激光器、乙烯基聚合物制造、纺织品铁、钙、铝、钽的测定、工业水中硬度的监测、饮用水中二氧化氯的测量、降血糖剂、核荧光染料等。 | |||
T68738 |
(±)-γ-Tocopherol
|
Others | Others |
(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties. It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays. It also reduces the synthesis of prostaglandin E2 (PGE2) induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells. (±)-γ-Tocopherol inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated... | |||
T37270 |
9(E),11(E)-12-nitro Conjugated Linoleic Acid
|
Others | Others |
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma. 1.Woodcock, S.R., Salvato... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T34642 |
Silicon dioxide
|
||
Silicon dioxide is a transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid. | |||
TN6754 |
1-Nonadecanol
|
Others | Others |
1-Nonadecanol 是一种 Heracleum thomsonii 的超临界二氧化碳精油的成分,也是 Neotinea ustulata 的重要香气化合物。 | |||
T5803 |
D(-)-Tartaric acid
|
Others | Others |
D(-)-Tartaric acid 存在于许多植物中,特别是罗望子和葡萄,口服后通过与碳酸氢钠相互作用产生二氧化碳。二氧化碳会延伸胃部并在双造影射线照相期间提供负造影剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01038 |
CA5A Protein, Human, Recombinant
Carbonic anhydrase VA,Carbonic anhydrase 5A, mitochondrial,C... |
Human | HEK293 Cells |
Reversible hydration of carbon dioxide. Low activity. CA5A Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 30.6 kDa and the accession number is P35218. | |||
TMPH-03258 |
Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO)
Cyanamide hydratase CA1,CA-I,Carbonate dehydratase I,Car1,Ca... |
Rat | E. coli |
Reversible hydration of carbon dioxide. Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.2 kDa and the accession number is B0BNN3. | |||
TMPH-00404 |
Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His)
AADase,EC:4.1.1.4,ADC,AAD |
Clostridium acetobutylicum | Baculovirus Insect Cells |
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide. Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is P23670. | |||
TMPJ-00283 |
Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated
G250,P54/58N,Carbonic Anhydrase IX,CA9,Carbonate dehydratase... |
Human | HEK293 Cells |
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC... | |||
TMPH-03259 |
Carbonic Anhydrase 2 Protein, Rat, Recombinant (His)
CA-II,Carbonate dehydratase II,Carbonic anhydrase II,Cyanami... |
Rat | E. coli |
Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. Carbonic Anhydrase 2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.7 kDa and the accession number is P27139. | |||
TMPH-00773 |
RuBisCO large subunit Protein, Glycine max, Recombinant (His & SUMO)
rbcL,Ribulose bisphosphate carboxylase large chain |
Glycine max | E. coli |
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. | |||
TMPY-01761 |
Carbonic Anhydrase 3 Protein, Human, Recombinant (His)
carbonic anhydrase III,CAIII,Car3 |
Human | E. coli |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Carbonic anhydrases (CAs) form a family of enzymes that catalyze the rapid conversion of carbon dioxide and water to bicarbonate an... | |||
TMPJ-01055 |
HBA1 Protein, Human, Recombinant (His)
α-globin,Hemoglobin subunit alpha,HBH,HBA-T3,Alpha-globin,He... |
Human | E. coli |
Hemoglobin subunit alpha 1 (HBA1), also known as α2β2, is a hetero-tetramer consisting of two α and two β subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the Fe2+ state. Cooperativity of Hemoglobin (Hb) in binding with O2 and allosteric regulatory binding properties with CO2, H+, Cl−, and 2,3-DPG (2,3-bisphosphoglycerate) are based on subunit interactions. HBA1 is the most common type of Hb in adult humans, which mediates the transport... | |||
TMPJ-00731 |
Carbonic Anhydrase 1 Protein, Human, Recombinant (His)
Carbonic Anhydrase B,Carbonate Dehydratase I,CA-I,Carbonic A... |
Human | E. coli |
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam... | |||
TMPJ-00701 |
Carbonic Anhydrase 11 Protein, Human, Recombinant (His)
Carbonic Anhydrase-Related Protein 2,CARP XI,CA11,CARP-2,Car... |
Human | HEK293 Cells |
Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA11 is expressed abundantly in the brain with moder... | |||
TMPJ-01374 |
UPB1 Protein, Human, Recombinant (His)
β-Ureidopropionase,Beta-Alanine Synthase,β-Alanine Synthase,... |
Human | E. coli |
β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. β-Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. β-Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide, respectively. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidi... | |||
TMPY-01877 |
CA5A Protein, Human, Recombinant (His)
CA5,GS1-21A4.1,CA5AD,carbonic anhydrase VA, mitochondrial,CA... |
Human | E. coli |
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospi... | |||
TMPY-02277 |
Carbonic Anhydrase 7 Protein, Human, Recombinant (His)
CAVII,carbonic anhydrase VII |
Human | E. coli |
Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, ... | |||
TMPY-01734 |
CA13 Protein, Human, Recombinant (His)
carbonic anhydrase XIII,FLJ37995,CAXIII,MGC59868 |
Human | E. coli |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. The CAXIII is a member of th... | |||
TMPY-02133 |
Carbonic Anhydrase VB Protein, Human, Recombinant (His)
carbonic anhydrase VB, mitochondrial,CA-VB,MGC39962 |
Human | E. coli |
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological process... |