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Search Results for " dihydrofolate "

Targets Recommended: Others DHFR

60

抑制剂 & 化合物

3

天然产物

4

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T3693	DHFR-IN-3 7-bromoquinazoline-2,4-diamine,7-溴-2,4-二氨基喹唑啉	Others; DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) 是一种二氢叶酸还原酶 (DHFR) 抑制剂。
T6120	Pralatrexate Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙	Apoptosis; DHFR; Antifolate; TAM Receptor	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Tyrosine Kinase/Adaptors
	Pralatrexate (10-Propargyl-10-deazaaminopterin) 是一种抗叶酸剂，也是二氢叶酸还原酶抑制剂，Ki 值为 13.4 pM。它具有抗肿瘤活性，可研究复发/难治性 T 细胞淋巴瘤。它是叶酰聚谷氨酸合成酶的底物，具有改善的细胞摄取和保留能力。
T29460	5-Methyldihydrofolate	Others	Others
	5-Methyldihydrofolate is the primary biologically active form of folate used for DNA reproduction, the cysteine cycle, and the regulation of homocysteine.
T20340	10-Formyldihydrofolate	Others	Others
	10-Formyldihydrofolate is a Methotrexate metabolite. It inhibits thymidylate synthetase and glycinamide ribotide transformylase.
T24962	10-Formylfolic acid	DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	10-Formylfolic acid 是一种新型有效的二氢叶酸还原酶 (dihydrofolate reductase) 抑制剂，可用于研究白血病。
T17257L	WR99210 hydrochloride(47326-86-3 free base) WR99210 hydrochloride(47326-86-3 free base),6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine	Others	Others
	WR99210 hydrochloride 是恶性疟原虫二氢叶酸还原酶 (pfDHFR) 的有效抑制剂，pfDHFR 是主要的疟疾药物靶点。它对野生型、双突变体和四突变体二氢叶酸还原酶具有亚纳摩尔效力。
T19858	Brodimoprim	DHFR; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Brodimoprim 是甲氧苄啶的一种类似物，是口服有效的二氢叶酸还原酶抑制剂，对广谱革兰氏阴性和革兰氏阳性细菌具有高度的抑制作用。
T0849	Pyrimethamine Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶	DHFR; Antifolate; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Pyrimethamine (Pirimecidan) 是一种二氢叶酸还原酶的竞争性抑制剂，用作抗疟药。
T25886	Methotrexate Diglutamate NSC-269401,NSC 269401,NSC269401	DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Methotrexate Diglutamate 存在于肝脏中的小分子化合物，可作为部分纯化的人二氢叶酸还原酶抑制剂。
TQ0113	Iclaprim 艾拉普林,AR-100	Antibacterial; Antibiotic	Microbiology/Virology
	Iclaprim (AR-100) 是一种细菌二氢叶酸的选择性新型抑制剂, 可抑制金黄色葡萄球菌的生长, 其 MIC90值为 0.06 μg/mL。
T24644	Piritrexim BW 301U	DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Piritrexim (BW 301U) 是一种可口服的脂溶性二氢叶酸还原酶抑制剂，具有肺毒性，用于研究尿路上皮癌和转移性乳腺癌。
T61486	DHFR-IN-4	DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	DHFR-IN-4 是一种高效的二氢叶酸还原酶 (DHFR) 抑制剂，具有抗肿瘤活性，抑制 EGFR 和 HER2 ，可用于研究胰腺癌。
T1485	Methotrexate NCI-C04671,WR19039,Amethopterin,甲氨蝶呤,CL14377	Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Methotrexate (WR19039) 是一种叶酸类似物，一种二氢叶酸还原酶 DHFR 的抑制剂。Methotrexate 具有抗代谢、抗肿瘤和免疫抑制等活性，常用于类风湿关节炎和多种肿瘤的研究。
T36692	Fanotaprim	DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Fanotaprim 是二氢叶酸还原酶的有效抑制剂，抑制 tgDHFR (Toxoplasma gondiiDHFR) 和 hDHFR (human DHFR)的 IC50分别为 1.57 和 308 nM。Fanotaprim 在研究弓形虫病方面具有价值。
T5420	Cycloguanil hydrochloride Chloroguanide Triazine,环氯胍盐酸盐	Parasite; Drug Metabolite	Metabolism; Microbiology/Virology
	Cycloguanil hydrochloride (Chloroguanide Triazine) 是抗疟化合物氯胍的活性代谢物。它作为二氢叶酸还原酶的抑制剂，对于疟原虫和人类形式的 Kis 值分别为 0.3 和 1.5 nM。
T64295	Talotrexin ammonium	DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Talotrexin ammonium 是一种不可多聚谷氨酸抗叶酸类药物。Talotrexin ammonium 通过针对二氢叶酸还原酶（DHFR）来抑制肿瘤生长，从而提高了在广泛癌症模型中的抗肿瘤活性，有助于抑制肿瘤的增长。
T20339	7-Hydroxymethotrexate NSC 380963,NSC-380963,NSC380962,NSC380963,NSC 380962,NSC-380962	Drug Metabolite	Metabolism
	7-Hydroxymethotrexate 是 Methotrexate 主要的代谢产物。Methotrexate 对叶酸具有抑制作用，抑制二氢叶酸还原酶，从而防止叶酸转化为四氢叶酸，并抑制 DNA 合成。Methotrexate 对代谢也具有抑制作用。
T4382	Proguanil hydrochloride Paludrine hydrochloride,盐酸氯胍,Chlorguanide hydrochloride,Chloroquanil	Others; Dehydrogenase; DNA/RNA Synthesis; Antifolate; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Others
	Proguanil hydrochloride (Chloroquanil) 是一种双胍类抗疟疾剂，在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。
T24459	Metioprim Ro126995,Ro 126995,He 909,He909,Ro 12-6995	Others	Others
	Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.
T30761	CB 3703 CB3703,NSC 289522,CB-3703	Others	Others
	CB 3703 is an inhibitor of dihydrofolate reductase and thymidylate synthase.
T23883	Chlorasquin Ccnsc-529,861,Ccnsc 529,861,SK 29861,Ccnsc529,861,SK-29861	Others	Others
	Chlorasquin is a dihydrofolate reductase inhibitor.
T17164	Trimetrexate 三甲曲沙,CI-898	Others	Others
	Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.
T24427	Lysine-methotrexate ADMPL	Others	Others
	Lysine-methotrexate is an anticancer drug. It is an inhibitor of dihydrofolate reductase.
T29003	TRC-19	Others	Others
	TRC-19 is a potent and selective inhibitor of Toxoplasma gondii dihydrofolate reductase. TRC-19 shows an IC50 of 9 nM and 89-fold selectivity in favor of Toxoplasma gondii dihydrofolate reductase.
T7730L	Aminopterin sodium NSC739,NSC 739 [as the base],NSC-739	Others	Others
	Aminopterin sodium is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effe
T24571	Ornithine-methotrexate ADMPO	Others	Others
	Ornithine-methotrexate is a ornithine analog of methotrexate. It is an inhibitors of dihydrofolate reductase.
T25381	Epiroprim Epiroprime,Ro11-8958,Ro 11-8958,Ro-11-8958	Others	Others
	Epiroprim is an analog of trimethoprim and a dihydrofolate reductase inhibitor.
T25079	Aminopterin N-hydroxysuccinimide ester Nhs-aminopterin,N-Hydroxysuccinimide aminopterin	Others	Others
	Aminopterin N-hydroxysuccinimide ester is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrof
T27002	CH-1504 CH 1504,MobileTrex	Others	Others
	CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.
T69591	Cycloguanil nitrate	Others	Others
	Cycloguanil nitrate is a dihydrofolate reductase inhibitor and is a metabolite of the antimalarial drug proguanil.
T25332	Dihydrohomofolic acid	Others	Others
	Dihydrohomofolic acid is a substrate for dihydrofolate reductase that produces tetrahydro-homo folate which in turn suppresses thymidylate synthetase and then DNA synthesis.
T70080	Methasquin	Others	Others
	Methasquin is a folic acid antagonist that has been used in the treatment of experimental leukemia; acts by inhibiting the dihydrofolate reductase in the cell.
T25324	Dichloromethotrexate NSC 29630,3988-B-129-4,NSC29630,Dichloroamethopterin,NSC-29630	Others	Others
	Dichloromethotrexate is an enzyme dihydrofolate reductase inhibitor, thus preventing the synthesis of purine nucleotides and thymidylates and inhibiting DNA and RNA synthesis. This agent is metabolized and excreted by the liver.
T22409	Proguanil 氯胍,chloroguanide,chlorguanide	Others	Others
	Proguanil, a prophylactic antimalarial drug, inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of pyrimidines and purines, which are essential for DNA synthesis and cell multiplication.
T68684	Piritrexim isethionate	Others	Others
	Piritrexim isethionate is a lipid-soluble inhibitor of dihydrofolate reductase (DHFR) that appears to be an active agent in patients with metastatic urothelial cancer when administered as a 5-day, low-dose oral schedule.
T12742	Ro 20-0657/000	Others	Others
	Ro 20-0657/000 is a Trimethoprim metabolite. Trimethoprim is an inhibitor of dihydrofolate reductase, used as an antibacterial agent in human and veterinary medicine.
T25981	Pralatrexate, (S)-	Others	Others
	Pralatrexate, (S)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively enters cells expressing RFC-1; intr
T25980	Pralatrexate, (R)-	Others	Others
	Pralatrexate, (R)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively enters cells expressing RFC-1; intr
T39862	Trimethoprim lactate	Others	Others
	Trimethoprim lactic is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactic is active against a wide range of Gram-positive and Gram-negative aerobic bacteria . Trimethoprim lactic has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment.
T25374	Emofolin sodium NSC139490,MeTHHF disodium,NSC-139490,NSC 139490	Others	Others
	Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity，which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, deple
T81639	NSC309401 dihydrochloride	Others	Others
	NSC309401为大肠杆菌DHFR抑制剂，具有IC50值为189 nM和KD值为14.57 nM。
T63985	Trimetrexate glucuronate	Others	Others
	Trimetrexate glucuronate (NSC 352122) 是一种叶酸拮抗剂，能够抑制二氢叶酸还原酶 (dihydrofolate reductase)，进而阻断嘌呤核苷酸和胸苷酸的合成，影响 DNA 和 RNA 合成，表现出潜在的抗肿瘤效果。
T79912	NSC309401	Others	Others
	NSC309401 是一种针对大肠杆菌DHFR的抑制剂，具有IC50值为189 nM和KD值为14.57 nM。
T69089	Trimethoprim sulfate	Others	Others
	Trimethoprim sulfate is a pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
T82571	DHFR-IN-10	Others	Others
	DHFR-IN-10（化合物4c）是针对结核分枝杆菌DHFR的高效抑制剂，其IC50为4.21 μM，显示出卓越的抗结核活性。
T75259	Baquiloprim	Others	Others
	Baquiloprim为一种抗生素，作为细菌二氢叶酸还原酶的选择性抑制剂，对革兰氏阴性及革兰氏阳性细菌展现体外抑菌活性。
T61272	EGFR/HER2-IN-7	Others	Others
	EGFR/HER2-IN-7 is a highly selective and potent anticancer compound specifically designed to target MCF-7 breast cancer cells. It functions as a dual inhibitor, targeting both EGFR/HER2 kinases and DHFR (dihydrofolate reductase). Its inhibitory activities are measured with IC50 values of 0.18 μM for EGFR, 0.146 μM for HER2, and 0.907 μM for DHFR [1].
T73328	DHFR-IN-5	Others	Others
	DHFR-IN-5 是一种有效且具有口服活性的二氢叶酸还原酶 (DHFR) 抑制剂，对Plasmodiumfalciparum 突变体的Ki 值为 0.54 nM。DHFR-IN-5显示抗疟疾活性[1]。
T74009	1,1,3-Tribromoacetone	Others	Others
	1,1,3-Tribromoacetone 是甲氨蝶呤的杂质。Methotrexate (Amethopterin) 是一种抗代谢 (antimetabolite) 和抗叶酸剂 (antifolate)，可抑制二氢叶酸还原酶，从而防止叶酸转化为四氢叶酸并抑制 DNA 合成。
T41148	Phototrexate	Others	Others
	Phototrexate is a photoswitchable potent inhibitor of human dihydrofolate reductase (DHFR). Phototrexate is a photochromic analog of Methotrexate. Antifolate activity is switched on (cis-Phototrexate) by UVA (375 nm) light; it can be switched off (trans-Phototrexate) by blue or white light and by thermal relaxation in the dark.cis-Phototrexate (IC50 = 6 nM) significantly reduces the viability of HeLa cells compared withtrans-Phototrexate (IC50 = 34 μM).

化合物

Cat.No: T3693

Synonym: 7-bromoquinazoline-2,4-diamine,7-溴-2,4-二氨基喹唑啉

Target: Others, DHFR

Cat.No: T6120

Synonym: Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙

Target: Apoptosis, DHFR, Antifolate, TAM Receptor

5-Methyldihydrofolate

Cat.No: T29460

Target: Others

10-Formyldihydrofolate

Cat.No: T20340

Target: Others

10-Formylfolic acid

Cat.No: T24962

Target: DHFR

WR99210 hydrochloride(47326-86-3 free base)

Cat.No: T17257L

Synonym: WR99210 hydrochloride(47326-86-3 free base),6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine

Target: Others

Cat.No: T19858

Target: DHFR, Antibacterial

Cat.No: T0849

Synonym: Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶

Target: DHFR, Antifolate, Parasite

Methotrexate Diglutamate

Cat.No: T25886

Synonym: NSC-269401,NSC 269401,NSC269401

Target: DHFR

Cat.No: TQ0113

Synonym: 艾拉普林,AR-100

Target: Antibacterial, Antibiotic

Cat.No: T24644

Synonym: BW 301U

Target: DHFR

Cat.No: T61486

Target: DHFR

Cat.No: T1485

Synonym: NCI-C04671,WR19039,Amethopterin,甲氨蝶呤,CL14377

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate, ADC Cytotoxin

Cat.No: T36692

Target: DHFR

Cycloguanil hydrochloride

Cat.No: T5420

Synonym: Chloroguanide Triazine,环氯胍盐酸盐

Target: Parasite, Drug Metabolite

Talotrexin ammonium

Cat.No: T64295

Target: DHFR

7-Hydroxymethotrexate

Cat.No: T20339

Synonym: NSC 380963,NSC-380963,NSC380962,NSC380963,NSC 380962,NSC-380962

Target: Drug Metabolite

Proguanil hydrochloride

Cat.No: T4382

Synonym: Paludrine hydrochloride,盐酸氯胍,Chlorguanide hydrochloride,Chloroquanil

Target: Others, Dehydrogenase, DNA/RNA Synthesis, Antifolate, Parasite

Cat.No: T24459

Synonym: Ro126995,Ro 126995,He 909,He909,Ro 12-6995

Target: Others

Cat.No: T30761

Synonym: CB3703,NSC 289522,CB-3703

Target: Others

Cat.No: T23883

Synonym: Ccnsc-529,861,Ccnsc 529,861,SK 29861,Ccnsc529,861,SK-29861

Target: Others

Cat.No: T17164

Synonym: 三甲曲沙,CI-898

Target: Others

Lysine-methotrexate

Cat.No: T24427

Synonym: ADMPL

Target: Others

Cat.No: T29003

Target: Others

Aminopterin sodium

Cat.No: T7730L

Synonym: NSC739,NSC 739 [as the base],NSC-739

Target: Others

Ornithine-methotrexate

Cat.No: T24571

Synonym: ADMPO

Target: Others

Cat.No: T25381

Synonym: Epiroprime,Ro11-8958,Ro 11-8958,Ro-11-8958

Target: Others

Aminopterin N-hydroxysuccinimide ester

Cat.No: T25079

Synonym: Nhs-aminopterin,N-Hydroxysuccinimide aminopterin

Target: Others

Cat.No: T27002

Synonym: CH 1504,MobileTrex

Target: Others

Cycloguanil nitrate

Cat.No: T69591

Target: Others

Dihydrohomofolic acid

Cat.No: T25332

Target: Others

Cat.No: T70080

Target: Others

Dichloromethotrexate

Cat.No: T25324

Synonym: NSC 29630,3988-B-129-4,NSC29630,Dichloroamethopterin,NSC-29630

Target: Others

Cat.No: T22409

Synonym: 氯胍,chloroguanide,chlorguanide

Target: Others

Piritrexim isethionate

Cat.No: T68684

Target: Others

Cat.No: T12742

Target: Others

Pralatrexate, (S)-

Cat.No: T25981

Target: Others

Pralatrexate, (R)-

Cat.No: T25980

Target: Others

Trimethoprim lactate

Cat.No: T39862

Target: Others

Emofolin sodium

Cat.No: T25374

Synonym: NSC139490,MeTHHF disodium,NSC-139490,NSC 139490

Target: Others

NSC309401 dihydrochloride

Cat.No: T81639

Target: Others

Trimetrexate glucuronate

Cat.No: T63985

Target: Others

Cat.No: T79912

Target: Others

Trimethoprim sulfate

Cat.No: T69089

Target: Others

Cat.No: T82571

Target: Others

Cat.No: T75259

Target: Others

Cat.No: T61272

Target: Others

Cat.No: T73328

Target: Others

1,1,3-Tribromoacetone

Cat.No: T74009

Target: Others

Cat.No: T41148

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T15128	Dihydrofolic acid 7,8-Dihydrofolic acid,Dihydrofolate	Others	Others
	Dihydrofolic acid (7,8-Dihydrofolic acid) 是一种叶酸衍生物，在二氢叶酸还原酶的作用下生成四氢叶酸。
T1153	Trimethoprim NIH 204,BW 56-72,甲氧苄啶,NSC-106568	DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Trimethoprim (NSC-106568) 是抑菌抗生素，也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性，可用于尿路感染，肺孢子菌肺炎和志贺氏菌病的研究。
T7730	Aminopterin APGA,氨基蝶呤,4-Aminofolic acid	Antifolate	Cell Cycle/Checkpoint
	Aminopterin (4-Aminofolic acid) 是叶酸的 4-氨基衍生物，是叶酸拮抗剂，具有抗癌和免疫抑制活性，用于研究儿童白血病。它催化叶酸还原为四氢叶酸，竞争性抑制二氢叶酸还原酶，Ki 值为 3.7 pM。

天然产物

Dihydrofolic acid

Cat.No: T15128

Synonym: 7,8-Dihydrofolic acid,Dihydrofolate

Target: Others

Cat.No: T1153

Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

Cat.No: T7730

Synonym: APGA,氨基蝶呤,4-Aminofolic acid

Target: Antifolate

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01224	Dihydrofolate reductase Protein, Human, Recombinant (His) DHFR,Dihydrofolate reductase	Human	E. coli
	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
TMPH-03535	Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) DHFR,Dihydrofolate reductase,folA	Staphylococcus aureus	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.6 kDa and the accession number is P99079.
TMPH-00608	Dihydrofolate reductase Protein, E. coli, Recombinant (His) Dihydrofolate reductase,folA,tmrA	E. coli	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-03581	Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) dfrC,folA1,Dihydrofolate reductase,folA,DHFR	Staphylococcus epidermidis	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.0 kDa and the accession number is P0C0P1.

重组蛋白

Dihydrofolate reductase Protein, Human, Recombinant (His)

Cat.No: TMPH-01224

Species: Human

Expression System: E. coli

Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03535

Species: Staphylococcus aureus

Expression System: E. coli

Dihydrofolate reductase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00608

Species: E. coli

Expression System: E. coli

Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)

Cat.No: TMPH-03581

Species: Staphylococcus epidermidis

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T10915	Cycloguanil D6 Nitrate Chlorguanide triazine D6 Nitrate	Others	Others
	Cycloguanil D6 Nitrate is a dihydrofolate reductase inhibitor, deuterium-labeled Cycloguanil.
T10916	Cycloguanil D6 Chlorguanide triazine D6	Others	Others
	Cycloguanil D6 is a dihydrofolate reductase inhibitor, deuterium-labeled Cycloguanil.
TMIH-0457	Proguanil-d6 HCl
	Proguanil-d6 HCl 是 Proguanil HCl 的氘代化合物。Proguanil HCl 的 CAS 号为 637-32-1。Proguanil hydrochloride 是一种双胍类抗疟疾剂，在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。

同位素标记化合物

Cycloguanil D6 Nitrate

Cat.No: T10915

Synonym: Chlorguanide triazine D6 Nitrate

Target: Others

Cat.No: T10916

Synonym: Chlorguanide triazine D6

Target: Others

Proguanil-d6 HCl

Cat.No: TMIH-0457

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