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Search Results for " cation "

Targets Recommended: advanced glycation end products Others

60

抑制剂 & 化合物

12

天然产物

2

化合物库

1

TargetMol 试剂盒

13

重组蛋白

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Cat. No.	Product Name
L3500	组蛋白修饰化合物库		469 compounds
	469 个组蛋白修饰相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L8300	染色质修饰分子库		250 compounds
	250 种染色质化学修饰相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

组蛋白修饰化合物库

Cat.No: L3500

Compounds: 469

染色质修饰分子库

Cat.No: L8300

Compounds: 250

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0050	BCA Protein Quantification Kit BCA蛋白浓度测定试剂盒	Solution in bottle

TargetMol 试剂盒

BCA蛋白浓度测定试剂盒

Cat.No: C0050

Cat. No.	Product Name	Target	Signaling Pathways
T68260	Calmidazolium (cation)	Others	Others
	Calmidazolium (cation) is a powerful inhibitor of or red blood cell Ca -ATPase & Ca transport into inside-out red blood cell vesicles; an antagonist of calmodulin.
T34817	Tetrabutylphosphonium cation Tetra-n-butylphosphonium,J279H,Tetrabutylphosphonium ion,Tetrabutylphosphonium,Phosphonium, tetrabutyl-	Others	Others
	Tetrabutylphosphonium cation is a light orange solid and is the salt of the liphilic tetrabutylammonium cation and linear tribromide anion.
T32984	LX-201 cation	Others	Others
	LX-201 cation is a bioactive chemical.
T25628	Lapyrium Lapyrium cation	Others	Others
	Lapyrium is a cationic surfactant that is used in personal care products as a biocide and antistatic. It is also used by the chloride salt, lapyrium chloride, in waste-water treatment and corrosion inhibition formulations.
T32592	Lauralkonium Lauralkonium ion,Lauralkonium cation	Others	Others
	Lauralkonium is a bioactive chemical.
T25640	Laurolinium Laurolinium ion,Laurolinium cation	Others	Others
	Laurolinium is an antimicrobial.
T25636	Laudexium Laudexium ion,Laudexium cation	Others	Others
	Laudexium is a neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle re
T26666	ASM-024	AChR	Neuroscience
	ASM-024是一种有效的烟碱受体激动剂，是一种小分子合成哌嗪化合物，可促进β2-肾上腺素受体不同的靶点和信号通路介导平滑肌松弛，是治疗哮喘和慢性阻塞性支气管炎的潜在化合物，具有抗炎活性。
T21623	AS1269574 AS 1269574	GPR; TRP/TRPV Channel	Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel
	AS1269574 是口服有效的GPR119激动剂，在表达人 GPR119 的 HEK293 细胞中EC50为 2.5 μM。它激活 TRPA1 阳离子通道，刺激胰高血糖素样肽-1分泌。它仅在高糖条件下特异性诱导胰腺 β 细胞分泌葡萄糖依赖性胰岛素。它在 2 型糖尿病的研究中具有价值。
T68783	Stercuronium	Others	Others
	Stercuronium is an aminosteroid neuromuscular blocking agent which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor, and is also reported to be an acetylcholinesterase inhibitor.
T68735	Ciclotropium (free base)	Others	Others
	Ciclotropium (free base) is quaternary ammonium compound with anticholinergic and parasympatholytic activity. Oral Cyclotropium bromide inhibited fasting and meal-stimulated colonic motility significantly without causing adverse side effects. After cyclotropium bromide, there was a significant correlation between antral contraction amplitude and gastric emptying.
T68502	Dibrospidium Free Base	Others	Others
	Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correlate with spirobromine antitumor activity. Spirobromin is superior to prospidin by the power of the anti-inflammatory effect. Spyrobromin can diminish the latent period of the development of tumours in the experimental rats at intraperitoneal administration. At intragastric admini...
T9776	TRPM4 inhibitor 8	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPM4 inhibitor 8 是瞬态受体电位 melastatin 4 (TRPM4) 的抑制剂，它有助于活力、迁移、细胞周期转变和粘附。
T70310	INCB-39110	Others	Others
	INCB-39110 is a JAK1 inhibitor.
T9245	TRPM4-IN-1 CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) 是一种有效的阳离子通道TRPM4选择性抑制剂，IC50为 1.5 μM。TRPM4-IN-1 在心脏病和前列腺癌中具有研究价值。
T1050	Prazosin hydrochloride Prazosin hydrochloride,哌唑嗪盐酸盐,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,盐酸哌唑嗪,Minipress	Potassium Channel; MRP; Adrenergic Receptor; ABC; Autophagy	Autophagy; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Prazosin hydrochloride (Vasoflex) 是一种选择性肾上腺素能 α-1 拮抗剂，可降低外周阻力并放松血管平滑肌。它可用于研究高血压和酒精使用障碍。它是一种合成哌嗪衍生物，具有降压抗肾上腺素能特性。它抑制有机阳离子转运蛋白 OCT-1 和 OCT-3，IC50分别为 1.8 和 13 μM 。
TQ0157	EIPA L593754,MH 12-43	Sodium Channel; TRP/TRPV Channel	Membrane transporter/Ion channel
	EIPA (L593754) 是一种有效的TRPP3 channel 抑制剂，IC50为 10.5 μM。EIPA 对Na+/H+交换 (NHE) 和巨噬细胞也有抑制作用。
T80024	Cationic Bovine Serum Albumin cBSA, chemically modified cationic bovine serum albumin	Others	Others
	Cationic Bovine Serum Albumin（带正电荷的牛血清白蛋白）是由583个氨基酸组成的蛋白质，具有三个同源的全α结构域。该蛋白质与Tanshinone IIA联用，在缺血性脑卒中中展现出显著的神经保护作用。
T81449	PKC-ε translocation inhibitor peptide	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	PKC-ε translocation inhibitor peptide，作为一种特定的PKC-ε易位抑制剂，能够特异性地调控FcγR介导的调理珠内化速率，而对FcαR运输不产生影响。
T74550	Cemdisiran, terminal sugar modification-	Others	Others
	Cemdisiran（终端糖基修饰）是一种靶向C5 mRNA的siRNA，通过N-乙酰半乳糖胺缀合增强RNAi活性，能够抑制肝脏中补体成分C5的生成。
T7538	Tetraethylammonium chloride	Potassium Channel	Membrane transporter/Ion channel
	Tetraethylammonium chloride 是非选择性钾通道阻滞剂。它是有机阳离子转运蛋白的良好底物，并具有抗肿瘤特性。
T28020	Mesendogen	TRP/TRPV Channel	Membrane transporter/Ion channel
	Mesendogen 是瞬时受体电位阳离子通道、亚家族 M、成员 6 (TRPM6) 和 7 (TRPM7) 的抑制剂，通过抑制 TRPM6/TRPM7 镁通道活性起作用。
T10247	Adenosine 5'-diphosphoribose sodium Adenosine 5'-diphosphoribose sodium,ADP ribose sodium	Endogenous Metabolite; TRP/TRPV Channel; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种烟酰胺腺嘌呤核苷酸 (NAD+) 的代谢产物，广泛存在于生物体内。Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种高效的细胞内 Ca2+ 渗透性阳离子 TRPM2 通道激活剂，还可以诱导自噬 (autophagy)。
T22537	9-Phenanthrol	TRP/TRPV Channel	Membrane transporter/Ion channel
	9-Phenanthrol 是瞬时受体电位 melastatin 4 (TRPM) 通道的抑制剂，这是一种 Ca2+ 激活的非选择性阳离子通道。
T16763	RN-1747	TRP/TRPV Channel	Membrane transporter/Ion channel
	RN-1747是瞬时受体电位阳离子通道 V 型亚家族成员4（TRPV4 ）的选择性激动剂，对 hTRPV4、mTRPV4 和 rTRPV4 的 EC50分别为0.77 μM、4.0 μM 和4.1 μM。RN-1747也是 TRPM8的拮抗剂，IC50值为4.0 μM。
T22353	Lanthanum(III) chloride heptahydrate	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Lanthanum(III) chloride heptahydrate 是一种无机化合物，用于生化研究，阻断二价阳离子通道，尤其是钙通道的活性。
T16686	Pyr10	TRP/TRPV Channel	Membrane transporter/Ion channel
	Pyr10 是吡唑衍生物，是TRPC3通道的选择性抑制剂。Pyr10抑制卡巴可刺激的TRPC3转染的 HEK293 细胞中的 Ca2+流入。它具有区分受体操纵的TRPC3和天然基质相互作用分子 1 (STIM1)/Orai1 通道的能力。
T1098	Denatonium benzoate 苯甲地那铵,THS-839	Others	Others
	Denatonium benzoate (THS-839) 是一种已知的最苦的化合物，可作为厌恶剂(苦味剂)，加入到工业酒精、防冻液、咬指甲癖预防、呼吸器面罩配合测试、动物驱虫剂、液体皂和洗发水中，防止不适当的摄取。
T70540	Pinokalant LOE-908	SARS-CoV; TRP/TRPV Channel	Membrane transporter/Ion channel; Microbiology/Virology
	Pinokalant (LOE-908) 是一种新型非选性阳离子通道抑制剂。Pinokalant 在体内实验中可显著减少皮质梗死体积，可改善缺血半影区的代谢和电生理状态，可减少大鼠大脑中动脉闭塞后急性期磁共振图像上的病变大小。Pinokalant是一种潜在的SARS-CoV-2蛋白酶抑制剂，可用于研究脑卒中。
TP1910L1	CALP1 acetate CALP1 acetate(145224-99-3 free base)	CaMK	Neuroscience
	CALP1 acetate 是一种钙调蛋白 (CaM) 激动剂（Kd 为 88 µM），可与 CaM EF-hand/Ca2+ 结合位点结合。 CALP1 通过抑制钙通道的开放来阻断钙流入和细胞凋亡（IC50 为 44.78 µM）。 CALP1 阻断谷氨酸受体通道并阻断储存操作的非选择性阳离子通道。 CALP1 激活依赖于 CaM 的磷酸二酯酶活性。
TP2158	TRV-120027 TFA TRV-120027 TFA (1234510-46-3 free base)	RAAS; Arrestin	Endocrinology/Hormones; GPCR/G Protein
	TRV-120027 TFA 是一种血管紧张素 II 介导的血管收缩抑制剂，可增加心肌细胞的收缩力。它是一种偏向 β-arrestin-1 的 AT1R 激动剂，可与 ß-arrestins 结合，同时阻断 G 蛋白信号传导。它通过阳离子通道亚家族 C3 (TRPC3) 偶联诱导急性儿茶酚胺分泌，并促进在质膜上形成由 AT1R-β-arrestin-1-TRPC3-PLCγ 组成的大分子复合物。
T38516	IDT307
	IDT307, an analog of the organic cation MPP+, serves as a specific fluorescent substrate for DAT, identified as APP+.
T0979L	Dequalinium acetate Dequadin acetate,Decalinium acetate	Others	Others
	Dequalinium is a quaternary ammonium cation and bolaamphiphile commonly available as the dichloride salt. The bromide, iodide, acetate, and undecenoate salts are known as well.
T68693	AZ12099548	Others	Others
	AZ12099548 is a transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist.
T22929	LOE 908 hydrochloride	Others	Others
	Broad spectrum cation channel blocker.This compound is unstable in powder form and other related salt forms are recommended.
T37086	PDDHV	Others	Others
	PDDHV is a resiniferatoxin-type phorboid vanilloid with capsaicin-like selectivity for the cloned rat transient receptor potential cation channel subfamily V member 1 (TRPV1), formerly known as vanilloid receptor 1. It induces Ca2+-uptake by rat dorsal root ganglion neurons with an EC50 value of 70 nM.
T37658	MitoP	Others	Others
	MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB . MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce MitoP. Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.
T22370	Mitoquinol mesylate	Others	Others
	Mitoquinol, a ubiquinone derivative, specifically accumulates in mitochondria due to the covalent attachment of the cation triphenylphosphonium. Mitoquinol is an antioxidant, protecting mitochondria from oxidative damage and preventing lipid peroxidation-
T76374	SPAI-1
	SPAI-1，特异性单价阳离子ATP酶抑制剂，源自猪十二指肠。能体外抑制Na+，K+-ATP酶和H+，K+-ATP酶，同时刺激Mg2+-ATP酶。
T35965	MitoTEMPOL	Others	Others
	MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling.
T81986	Kayexalate	Others	Others
	Kayexalate，一种阳离子交换树脂，用作口服血浆钾离子抑制剂，适用于高钾血症的研究。
T78513	Sodium zirconium cyclosilicate	Others	Others
	Sodium zirconium cyclosilicate 是一种新型口服、不吸收的无机微孔硅酸盐锆化合物，高选择性地作为阳离子交换剂，专门用于去除体内过量的K+。该化合物适用于慢性肾脏疾病（CKD）的研究。
T37550	Bacitracin Complex	Others	Others
	Bacitracin complex is a bacitracin antibiotic complex composed of cyclic dipeptides that has been found inBacillus.1It is metal-dependent and is complexed to a divalent metal cation, such as Cu2+, Ni2+, Co2+, Zn2+, or Mn2+, for its activity.1,2Bacitracin complex is a mixture of bacitracin polypeptides in complex with copper. 1.Piacham, T., Isarankura-Na-Ayudhya, C., Nantasenamat, C., et al.Metalloantibiotic Mn(II)-bacitracin complex mimicking manganese superoxide dismutaseBiochem. Biophys. Res. ...
T28047	Mitoquinone-cyclodextrin MitoQ10,Mitoubiquinone mesylate,MitoQ-10,MitoQ,Mito Q10,Mitoquinone mesylate-cyclodextrin	Others	Others
	Mitoquinone-cyclodextrin is a 1:1 molar ratio complex of Mitoquinone mesylate with cyclodextrin. Mitoquinone mesylate is a mitochondria-targeted antioxidant designed to accumulate within mitochondria in vivo in order to protect against oxidative damage. M
T62272	TRPC6-IN-3	Others	Others
	TRPC6-IN-3 (compound 17) 是一种口服具有活力的瞬时受体电位 C6 离子通道 (TRPC6) 抑制剂。TRPC6-IN-3 能够调节细胞内钙浓度，也能够调节包括钙离子和钠离子在内的阳离子通量来调节膜电位。TRPC6-IN-3 可以用于研究呼吸系统。
T36745	cDPCP	Others	Others
	cDPCP is a platinum-containing DNA-crosslinking agent.1Unlike cisplatin or oxaliplatin , cDPCP forms monofunctional DNA adducts. It is transported into cells by organic cation transporter 1 (OCT1) and OCT2, inhibiting proliferation of MDCK cells expressing the human transporters with IC50values of 8.1 and 1.5 μM, respectively. cDPCP inhibits RNA polymerase II-mediated transcription in a reporter assay using HeLa cells. It increases survival in murine S180 sarcoma and P388 leukemia models when ad...
T35964	MitoTEMPO hydrate	Others	Others
	MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.[1] This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. Mitochondrial targeting of superoxide scavenging via mitoTEMPO has been examined for potential therapeutic benefit to a variety of mitochondrial dysfunctions arising from...
T37697L	D-GsMTx4 TFA	TRP/TRPV Channel; Piezo Channel	Membrane transporter/Ion channel
	D-GsMTx4 TFA 是一种具有选择性的蜘蛛毒液肽，是一种TRPC1 / 6和Piezo2抑制剂，可抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透的机械敏感性通道（MSCs），阻断阳离子选择性的拉伸激活通道（SAC），减弱溶血磷脂酰胆碱（LPC）诱导的星形胶质细胞毒性和小胶质细胞反应性。D-GsMTx4 TFA 在小鼠缺血/再灌注模型中预防心肌梗死，可用于鉴定兴奋性 MSC 在正常生理学和病理学中的作用。
T35963	MitoPerOx
	MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cation component that drives its accumulation in mitochondria. MitoPerOx displays an excitation maximum of 495 nm and exhibits a shift in emission maxima from 590 to 520 nm upon mitochondrial lipid peroxidation, enabling determination of ratiometric measurements of lipid peroxidatio...
T71295	SOR-C13
	SOR-C13 is an inhibitor of transient receptor potential cation channel vanilloid family member 6 (TRPV6, CaT1 or CATL) with potential antineoplastic activity. TRPV6 calcium channel inhibitor SOR-C13 binds to TRPV6 and prevents the influx of calcium ions into TRPV6-expressing tumor cells. This inhibits the activation of nuclear factor of activated T-cell (NFAT) transcription complex which may result in an inhibition of calcium-dependent cancer cell proliferation and an induction of apoptosis in t...

化合物

Calmidazolium (cation)

Cat.No: T68260

Target: Others

Tetrabutylphosphonium cation

Cat.No: T34817

Synonym: Tetra-n-butylphosphonium,J279H,Tetrabutylphosphonium ion,Tetrabutylphosphonium,Phosphonium, tetrabutyl-

Target: Others

LX-201 cation

Cat.No: T32984

Target: Others

Cat.No: T25628

Synonym: Lapyrium cation

Target: Others

Cat.No: T32592

Synonym: Lauralkonium ion,Lauralkonium cation

Target: Others

Cat.No: T25640

Synonym: Laurolinium ion,Laurolinium cation

Target: Others

Cat.No: T25636

Synonym: Laudexium ion,Laudexium cation

Target: Others

Cat.No: T26666

Target: AChR

Cat.No: T21623

Synonym: AS 1269574

Target: GPR, TRP/TRPV Channel

Cat.No: T68783

Target: Others

Ciclotropium (free base)

Cat.No: T68735

Target: Others

Dibrospidium Free Base

Cat.No: T68502

Target: Others

TRPM4 inhibitor 8

Cat.No: T9776

Target: TRP/TRPV Channel

Cat.No: T70310

Target: Others

Cat.No: T9245

Synonym: CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid

Target: TRP/TRPV Channel

Prazosin hydrochloride

Cat.No: T1050

Synonym: Prazosin hydrochloride,哌唑嗪盐酸盐,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,盐酸哌唑嗪,Minipress

Target: Potassium Channel, MRP, Adrenergic Receptor, ABC, Autophagy

Cat.No: TQ0157

Synonym: L593754,MH 12-43

Target: Sodium Channel, TRP/TRPV Channel

Cationic Bovine Serum Albumin

Cat.No: T80024

Synonym: cBSA, chemically modified cationic bovine serum albumin

Target: Others

PKC-ε translocation inhibitor peptide

Cat.No: T81449

Target: PKC

Cemdisiran, terminal sugar modification-

Cat.No: T74550

Target: Others

Tetraethylammonium chloride

Cat.No: T7538

Target: Potassium Channel

Cat.No: T28020

Target: TRP/TRPV Channel

Adenosine 5'-diphosphoribose sodium

Cat.No: T10247

Synonym: Adenosine 5'-diphosphoribose sodium,ADP ribose sodium

Target: Endogenous Metabolite, TRP/TRPV Channel, Autophagy

Cat.No: T22537

Target: TRP/TRPV Channel

Cat.No: T16763

Target: TRP/TRPV Channel

Lanthanum(III) chloride heptahydrate

Cat.No: T22353

Target: Calcium Channel

Cat.No: T16686

Target: TRP/TRPV Channel

Denatonium benzoate

Cat.No: T1098

Synonym: 苯甲地那铵,THS-839

Target: Others

Cat.No: T70540

Synonym: LOE-908

Target: SARS-CoV, TRP/TRPV Channel

Cat.No: TP1910L1

Synonym: CALP1 acetate(145224-99-3 free base)

Target: CaMK

Cat.No: TP2158

Synonym: TRV-120027 TFA (1234510-46-3 free base)

Target: RAAS, Arrestin

Cat.No: T38516

Dequalinium acetate

Cat.No: T0979L

Synonym: Dequadin acetate,Decalinium acetate

Target: Others

Cat.No: T68693

Target: Others

LOE 908 hydrochloride

Cat.No: T22929

Target: Others

Cat.No: T37086

Target: Others

Cat.No: T37658

Target: Others

Mitoquinol mesylate

Cat.No: T22370

Target: Others

Cat.No: T76374

Cat.No: T35965

Target: Others

Cat.No: T81986

Target: Others

Sodium zirconium cyclosilicate

Cat.No: T78513

Target: Others

Bacitracin Complex

Cat.No: T37550

Target: Others

Mitoquinone-cyclodextrin

Cat.No: T28047

Synonym: MitoQ10,Mitoubiquinone mesylate,MitoQ-10,MitoQ,Mito Q10,Mitoquinone mesylate-cyclodextrin

Target: Others

Cat.No: T62272

Target: Others

Cat.No: T36745

Target: Others

MitoTEMPO hydrate

Cat.No: T35964

Target: Others

Cat.No: T37697L

Target: TRP/TRPV Channel, Piezo Channel

Cat.No: T35963

Cat.No: T71295

Cat. No.	Product Name	Target	Signaling Pathways
T10662L	Calcimycin Antibiotic A-23187,离子载体(钙镁盐混合物),A-23187	Apoptosis; Antibacterial; Antibiotic; Autophagy; Antifungal	Apoptosis; Autophagy; Microbiology/Virology
	Calcimycin (A-23187) 是抗生素和二价阳离子离子载体。它抑制革兰氏阳性细菌和一些真菌生长，也抑制 ATP 酶的活性并解耦哺乳动物细胞的氧化磷酸化。它通过增加细胞内钙浓度诱导 Ca2+依赖性细胞死亡。
T1045	Trimipramine maleate Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐	Dopamine Receptor; 5-HT Receptor; Antibacterial; Adrenergic Receptor; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Trimipramine maleate (Surmontil maleate) 是一种 5-HT 受体拮抗剂，对 5-HT1C、5-HT2和 5-HT1A 受体的 pKi 值分别为 6.39、8.10和 4.66。
TQ0192	Senecionine Aureine,Senecionan-11,16-dione, 12-hydroxy-,千里光宁,Senecionin	Others	Others
	Senecionine 是一种吡咯里西啶生物碱，从Senecio vulgaris中分离得到，它对动物和人类有毒性。
T5288	Cytidine-5'-triphosphate disodium 胞苷 5'-三磷酸二钠盐,CTP,Cytidine 5'-triphosphate (disodium salt)	Others; Endogenous Metabolite	Metabolism; Others
	Cytidine 5'-triphosphate disodium salt 是内源性代谢产物的一种，是一种阳离子渗透性配体门控离子通道激动剂。
T4S0779	D-tetrahydropalmatine	Others; Dopamine Receptor	GPCR/G Protein; Neuroscience; Others
	D-Tetrahydropalmatine 是一种主要存在于延胡索类植物中的异喹啉生物碱。它是有机阳离子转运蛋白 1 抑制剂。它是多巴胺受体拮抗剂，对 D1 受体具有优先亲和力。
T1153	Trimethoprim NIH 204,BW 56-72,甲氧苄啶,NSC-106568	DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Trimethoprim (NSC-106568) 是抑菌抗生素，也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性，可用于尿路感染，肺孢子菌肺炎和志贺氏菌病的研究。
T2994	(E)-Cardamonin Alpinetin chalcone,Cardamomin,小豆蔻明,Cardamonin,(E)-Cardamoni,豆蔻明	Apoptosis; TRP/TRPV Channel	Apoptosis; Membrane transporter/Ion channel
	(E)-Cardamonin (Alpinetin chalcone) 是一种新型hTRPA1阳离子通道拮抗剂，IC50值为454 nM。
TN1909	Malvidin-3-glucoside chloride 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride	Others	Others
	Malvidin-3-glucoside chloride (Oenin chloride) 是一种主要的葡萄酒花青素，能够调节大脑突触可塑性和外周炎症，促进应激反应的发生。
TN2798	20-Deoxocarnosol	ROS; Antifection	Immunology/Inflammation; Microbiology/Virology
	20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity.
T10662	Calcimycin hemicalcium salt Antibiotic A-23187 hemicalcium salt,A-23187 hemicalcium salt	Others	Others
	Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration.
TN1361	(+)-Afzelechin 阿夫儿茶精,(+)-阿夫儿茶精	Others	Others
	(+)-Afzelechin has a neuroprotective effect on the glutamate-induced neurotoxicity in HT22 cells, it has ABTS cation radical scavenging effects with IC50 values of 23.7 microM
T36439	Gramicidin A	Antibacterial; HIF; Parasite	Angiogenesis; Chromatin/Epigenetic; Microbiology/Virology
	Gramicidin A 是一种从从 B. brevis 分离出来的多肽类抗生素。Gramicidin A 是一种高度疏水的通道形成离子载体，在人工膜中形成一价阳离子可渗透的通道。Gramicidin A 诱导缺氧诱导因子 1α (HIF-1α) 的降解，并能降低人肾细胞癌小鼠异种移植模型的生长。Gramicidin A 具有抗菌、抗疟活性以及溶血活性。

天然产物

Cat.No: T10662L

Synonym: Antibiotic A-23187,离子载体(钙镁盐混合物),A-23187

Target: Apoptosis, Antibacterial, Antibiotic, Autophagy, Antifungal

Trimipramine maleate

Cat.No: T1045

Synonym: Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐

Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor

Cat.No: TQ0192

Synonym: Aureine,Senecionan-11,16-dione, 12-hydroxy-,千里光宁,Senecionin

Target: Others

Cytidine-5'-triphosphate disodium

Cat.No: T5288

Synonym: 胞苷 5'-三磷酸二钠盐,CTP,Cytidine 5'-triphosphate (disodium salt)

Target: Others, Endogenous Metabolite

D-tetrahydropalmatine

Cat.No: T4S0779

Target: Others, Dopamine Receptor

Cat.No: T1153

Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

Cat.No: T2994

Synonym: Alpinetin chalcone,Cardamomin,小豆蔻明,Cardamonin,(E)-Cardamoni,豆蔻明

Target: Apoptosis, TRP/TRPV Channel

Malvidin-3-glucoside chloride

Cat.No: TN1909

Synonym: 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride

Target: Others

20-Deoxocarnosol

Cat.No: TN2798

Target: ROS, Antifection

Calcimycin hemicalcium salt

Cat.No: T10662

Synonym: Antibiotic A-23187 hemicalcium salt,A-23187 hemicalcium salt

Target: Others

Cat.No: TN1361

Synonym: 阿夫儿茶精,(+)-阿夫儿茶精

Target: Others

Cat.No: T36439

Target: Antibacterial, HIF, Parasite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03389	TRPA1 Protein, Rat, Recombinant (His & Myc) Wasabi receptor,Trpa1,Transient receptor potential catio...	Rat	E. coli
	TRPA1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.3 kDa and the accession number is Q6RI86.
TMPH-03390	TRPV2 Protein, Rat, Recombinant (His) Transient receptor potential cation channel subfami...	Rat	E. coli
	Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. TRPV2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 88.2 kDa and th...
TMPH-00484	Cationic trypsin Protein, Canine, Recombinant (His & SUMO) TRP1,Serine protease 1,PRSS1,TRY1,Pretrypsinogen I,Anionic t...	Canine	E. coli
	Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPK-01354	IGF2R Protein, Human, Recombinant (His & Avi) M6P/IGF2R,IGF-II receptor,MPRI,CI-MPR,CD222,MPR 300,M6PR	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717.
TMPK-01353	IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) CI-MPR,MPR 300,MPRI,M6P/IGF2R,M6PR,CD222,IGF-II receptor	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.50 kDa and the accession number is P11717.
TMPK-01361	IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated MPR 300,IGF-II receptor,M6PR,M6P/IGF2R,CD222,MPRI,CI-MPR	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717.
TMPH-02568	CTGF/CCN2 Protein, Mouse, Recombinant (GST) betaIG-M2,Connective tissue growth factor,Protein FISP-12,Fi...	Mouse	E. coli
	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
TMPH-03043	PIA Protein, MenB, Recombinant (His) Major outer membrane protein P.IA,Class 1 protein,porA	MenB	E. coli
	Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
TMPH-01069	CTGF/CCN2 Protein, Human, Recombinant (His) Hypertrophic chondrocyte-specific protein 24,CCN family memb...	Human	E. coli
	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. CTGF/CCN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.1 kDa and...
TMPH-02336	TAS2R10 Protein, Human, Recombinant (His & KSI) Taste receptor family B member 2,Taste receptor type 2 membe...	Human	E. coli
	Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. TAS2R10 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.6 kDa and the accession number is Q9NYW0.
TMPK-01355	IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) IGF-II receptor,CI-MPR,CD222,M6P/IGF2R,MPRI,M6PR,MPR 300	Human	HEK293 Cells
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 117.40 kDa and the accession number is P11717.
TMPH-02905	TRPC1 Protein, Mouse, Recombinant (His) Transient receptor protein 1,Short transient receptor potent...	Mouse	E. coli
	Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. TRPC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 94.0 kDa and the accession number is Q61056.
TMPH-02740	IL-31R alpha Protein, Mouse, Recombinant (His) ZcytoR17,Interleukin-31 receptor subunit alpha,Novel cytokin...	Mouse	E. coli
	Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. IL-31R alpha Protein, Mouse, Recombinant (His) is expressed in E. coli expression...

重组蛋白

TRPA1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03389

Species: Rat

Expression System: E. coli

TRPV2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03390

Species: Rat

Expression System: E. coli

Cationic trypsin Protein, Canine, Recombinant (His & SUMO)

Cat.No: TMPH-00484

Species: Canine

Expression System: E. coli

IGF2R Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01354

Species: Human

Expression System: HEK293 Cells

IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01353

Species: Human

Expression System: HEK293 Cells

IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01361

Species: Human

Expression System: HEK293 Cells

CTGF/CCN2 Protein, Mouse, Recombinant (GST)

Cat.No: TMPH-02568

Species: Mouse

Expression System: E. coli

PIA Protein, MenB, Recombinant (His)

Cat.No: TMPH-03043

Species: MenB

Expression System: E. coli

CTGF/CCN2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01069

Species: Human

Expression System: E. coli

TAS2R10 Protein, Human, Recombinant (His & KSI)

Cat.No: TMPH-02336

Species: Human

Expression System: E. coli

IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01355

Species: Human

Expression System: HEK293 Cells

TRPC1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02905

Species: Mouse

Expression System: E. coli

IL-31R alpha Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02740

Species: Mouse

Expression System: E. coli

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