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Sp-8-Br-cGMPS,一种cGMP的类似物,主要作用为激活cGMP门控阳离子通道(CNG channels),其EC50值达到106.5 μM。尽管Sp-8-Br-cGMPS能够诱导电流,但其无法维持通道的稳定开放,与完全激动剂存在差异。
Sp-8-Br-cGMPS,一种cGMP的类似物,主要作用为激活cGMP门控阳离子通道(CNG channels),其EC50值达到106.5 μM。尽管Sp-8-Br-cGMPS能够诱导电流,但其无法维持通道的稳定开放,与完全激动剂存在差异。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Sp-8-Br-cGMPS, an analogue of cGMP, acts as an agonist for cGMP gated cation channels (CNG channels) with an EC50 of 106.5 μM. While Sp-8-Br-cGMPS can induce currents, it does not stabilize channel open states as effectively as a full agonist. |
分子量 | 440.17 |
分子式 | C10H11BrN5O6PS |
CAS No. | 153660-03-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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