首页工具

登录

搜索结果

Search Results for " catabolism "

Targets Recommended: Others

38

抑制剂 & 化合物

17

天然产物

2

化合物库

22

重组蛋白

4

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L5200	抗代谢疾病化合物库		1544 compounds
	1544 个代谢疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2560	代谢化合物库		2320 compounds
	2320 种代谢途径相关的化合物，可用于高通量和高内涵筛选。

化合物库

抗代谢疾病化合物库

Cat.No: L5200

Compounds: 1544

代谢化合物库

Cat.No: L2560

Compounds: 2320

Cat. No.	Product Name	Target	Signaling Pathways
T20540	N-Valyltryptophan 二肽-2,Val-trp,L-Valyl-L-tryptophan	Others	Others
	N-Valyltryptophan (Val-trp) 是蛋白质分解代谢或蛋白质消化的不完全分解产物。
T8104	Glycyl-L-valine	Others; Endogenous Metabolite	Metabolism; Others
	Glycyl-L-valine 是含有甘氨酸和缬氨酸的二肽。
T38173	Propargylcholine Propargylcholine (bromide)	Antibacterial	Microbiology/Virology
	Propargylcholine (Propargylcholine (bromide)) 是一种炔烃修饰的胆碱类似物，在铜绿假单胞菌中 Dgc 酶催化的二甲基甘氨酸去甲基化水平上抑制胆碱分解代谢。
T68182L	3-Hydroxykynurenamine Dihydrochloride 3-OH-Kynurenamine HCl,3-Hydroxykynurenamine HCl（99362-47-7 Free base）	Others	Others
	3-Hydroxykynurenamine HCl (3-OH-Kynurenamine HCl) 是一种免疫调节生物胺，是氨基酸分解代谢的中间体，可诱导氧化损伤和促进细胞死亡。
T4179	Probucol disuccinate	LDL	Metabolism
	Probucol disucinate 是一种 Probucol 的衍生物。其中 Probucol 是脂质调节的化合物，它能降低 LDL-cholesterol 水平。
T0128	Vigabatrin Sabril,Vigabatrine,氨己烯酸	GABA Receptor; ABC	Membrane transporter/Ion channel; Neuroscience
	Vigabatrin (Sabril) 是 γ-氨基丁酸的类似物，是 4-氨基丁酸转氨酶的不可逆抑制剂，负责 γ-氨基丁酸分解代谢。它可用于可卡因依赖的治疗。
T10509	Xanthine oxidase-IN-1 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid	Xanthine Oxidase	Metabolism
	Xanthine oxidase-IN-1是一种有效的黄嘌呤氧化酶抑制剂(IC50值:6.5 nM),是一种利用核酸和核苷酸介质降解产生的生物活性核苷酸在嘌呤分解代谢中起核心作用的化合物，
T4374	Edoxudine 依度尿苷,Aedurid,EUDR,Epoxudine,乙去氧尿啶	Antiviral; Antibacterial	Immunology/Inflammation; Microbiology/Virology
	Edoxudine (Epoxudine) 是胸苷的类似物，是一种抗病毒药物，对单纯疱疹病毒有效。
T50094	DL-Willardiine 2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid	Others	Others
	DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) 是一种非天然氨基酸，谷氨酸的衍生物。它是mGluR5的激动剂，可以调节参与神经递质合成和分解的酶的活性，并影响离子通道和其他膜蛋白的活性。
T1602	Valproic acid sodium salt 丙戊酸钠,Sodium Valproate	Mitophagy; Gamma-secretase; HIV Protease; GABA Receptor; HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome; Stem Cells
	Valproic acid sodium salt (Sodium Valproate) 是一种HDAC 抑制剂，可抑制HDAC1的活性，诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、偏头痛和双相情感障碍等。
T30129	Arginylproline Arg-pro	Others	Others
	Arginylproline is a dipeptide composed of arginine and proline. It is an incomplete breakdown product of protein digestion or protein catabolism.
T29828	Alanyltyrosine
	Alanyltyrosine is a dipeptide composed of alanine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T33083	Lysyl threonine L-Threonine, l-lysyl-,Dipeptide-7,Dipeptide KT	Others	Others
	Lysyl threonine is a dipeptide composed of lysine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T33323	Methionyltryptophan Met-trp,Methionyl-tryptophan,Methionyl tryptophan	Others	Others
	Methionyl-Tryptophan is a dipeptide composed of methionine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism.
T30128	Arginylphenylalanine L-Arg-L-phe	Others	Others
	Arginylphenylalanine, a dipeptide composed of arginine and phenylalanine, is an incomplete breakdown product of protein digestion or protein catabolism.
T35032	Valyllysine Val-lys,Valyl-lysine	Others	Others
	Valyllysine is a dipeptide composed of valine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T31161	Cysteinyllysine	Others	Others
	Cysteinyllysine is a dipeptide composed of cysteine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T40932	Benzylacyclouridine 5-Benzylacyclouridine,BAU	Others	Others
	Benzylacyclouridine (BAU) is a powerful and selective inhibitor of uridine phosphorylase, the initial enzyme involved in uridine catabolism. Additionally, it can regulate the cytotoxic adverse effects of 5-fluorouracil (5-FU) and its derivatives.
T31162	Cysteinyltyrosine N-L-Cysteinyl-L-tyrosine,Cys-tyr	Others	Others
	Cysteinyltyrosine is a dipeptide composed of cysteine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T36724	6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro Prostaglandin F1α	Others	Others
	6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. It was shown to enhance intracellular cAMP and cholesterol catabolism in bovine arterial smooth muscle cells.
T37809	Alphitonin	Others	Others
	Alphitonin is a flavonoid that has been found in L. leptolepis wood.1 It is also a metabolic intermediate that is formed during the catabolism of quercetin by the human gut bacteria E. ramulus.2,3 \|1. Chen, K., Ohmura, W., Doi, S., et al. Termite feeding deterrent from Japanese larch wood. Bioresour. Technol. 95(2), 129-134 (2004).\|2. Braune, A., Gütschow, M., Engst, W., et al. Degradation of quercetin and luteolin by Eubacterium ramulus. Appl. Environ. Microbiol. 67(12), 5558-55567 (2001).\|3. J...
T36842	Isobutyryl Coenzyme A (sodium salt)	Others	Others
	Isobutyryl coenzyme A (isobutyryl-CoA) is a short-chain branched acyl CoA. Isobutyryl-CoA is a substrate for isobutyryl-CoA dehydrogenase (IBDH) in the catabolism of valine and an intermediate in the synthesis of isobutyryl-L-carnitine , which accumulates in IBDH deficiency.
T0128L	Vigabatrin Hydrochloride 盐酸氨己烯酸,γ-Vinyl-GABA hydrochloride	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) 是抑制性神经递质 GABA 乙烯基衍生物，不可逆地抑制 GABA 转氨酶对 GABA 的分解代谢，增加脑中 GABA 的水平。
T35886	L-hydroxy Arginine (acetate)
	L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome.
T74651	L-Inosine	Others	Others
	L-Inosine 是 L-构型形式的 Inosine。Inosine 是一种由腺苷分解代谢产生的内源性嘌呤核苷。Inosine 具有抗炎免疫调节，抗伤害和神经保护作用。
T33088	Lysylcysteine LYS CYS,LYS-CYS,L-Cysteine, L-lysyl-,LYSCYS	Others	Others
	Lysylcysteine is a dipeptide composed of lysine and cysteine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived
T34019	Phenylalanylglutamate Phe-glu	Others	Others
	Phenylalanylglutamate is a dipeptide composed of phenylalanine and glutamate. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are sim
T33091	Lysyllysine Lys-lys,L-Lys-L-lys	Others	Others
	Lysyllysine is a dipeptide composed of two lysine residues. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived in
T81233	S-(p-Nitrobenzyl)glutathione	Others	Others
	S-(p-Nitrobenzyl)glutathione 是一种竞争性谷胱甘肽酶(GGT)抑制剂，能被大鼠肾微粒体转化成相应的半胱氨酸衍生物。该化合物用于研究谷胱甘肽酶系统中GSH的代谢及其降解过程。
T37755	Phenylacetyl-Coenzyme A (sodium salt)	Others	Others
	Phenylacetyl-coenzyme A (CoA) is a key intermediate in aerobic catabolism of phenylacetate in bacteria such asPseudomonas, when cultured in minimal media using phenylacetate as the sole carbon source.1It is a precursor in the synthesis of the antibiotic penicillin G found in industrial strains ofP. chrysogenum. Phenylacetyl-CoA also acts as an effector molecule of the TetR family transcriptional repressor PaaR inT. thermophilusand the GntR family transcriptional regulator PaaX inE. coliandPseudo...
T17059	Tetrahydrouridine NSC 112907,NSC112907,四氢尿苷,NSC-112907	DNA Methyltransferase	Chromatin/Epigenetic
	Tetrahydrouridine (NSC-112907; THU) 是一种多药耐药调节剂。它可用于癌症治疗，使肿瘤细胞对放射治疗更加敏感。它是一种竞争性胞苷脱氨酶 (CDA) 抑制剂，可抑制 ara-C 和吉西他滨等细胞毒性脱氧胞苷类似物分解代谢中的脱氨作用。
T60348	N1,N11-Diethylnorspermine	Others	Others
	N1,N11-Diethylnorspermine (DENSPM) 是一种有效的抗癌剂。N1,N11-Diethylnorspermine 是一种精胺类似物,可激活多胺分解代谢。N1,N11-Diethylnorspermine 诱导细胞色素 c 从线粒体中释放，导致 caspase 3的激活。N1,N11-Diethylnorspermine 通过诱导亚精胺/精胺 N1- 乙酰转移酶 (SSAT) 结合产生过氧化氢杀灭多形胶质母细胞瘤 (GBM) 细胞。
T36921	16α-Hydroxyetiocholanolone	Others	Others
	16α-Hydroxyetiocholanolone is a metabolite of 16α-hydroxydehydroisoandrosterone (16α-DHEA) and androstenedione.1,2 1.Lai, E.Y., and Solomon, S.The in vivo metabolism of 16ɑ-hydroxydehydroisoandrosterone in manBiochemistry6(7)2040-2052(1967) 2.Christakoudi, S., Cowan, D.A., Christakudis, G., et al.21-hydroxylase deficiency in the neonate - trends in steroid anabolism and catabolism during the first weeks of lifeJ. Steroid Biochem. Mol. Biol.138334-347(2013)
T85123	3-Aminoisobutyric Acid sodium BAIBA,β-Aminoisobutyric Acid	Others	Others
	3-Aminoisobutyric acid, a non-protein amino acid resultant from thymine catabolism, plays a significant role in metabolic activities. At a 5 µM concentration, it triggers browning in primary adipocytes, notably elevating uncoupling protein 1 (UCP-1) and CIDEA expression. Additionally, it boosts PPARα expression in both primary adipocytes and mouse inguinal white adipose tissue (WAT) in vivo, alongside enhancing β-oxidation in hepatocytes. Its plasma levels surge post-exercise in mice, and its ad...
T37354	CAY10680 CAY10680	Others	Others
	CAY10680 is a dopamine-sparing, benzothiazinone compound that selectively inhibits both MAO-B activity (IC50 = 34.9 nM in human) and adenosine A2A receptors (Ki = 39.5 nM in human). It demonstrates significantly less potent inhibitory values for other adenosine receptor subtypes (Kis > 1 μM) and MAO-A (IC50 ≥ 10 μM). At 1-20 μM, CAY10680 has been shown to abolish cAMP accumulation in CHO cells transfected with adenosine A2A receptors. In the central nervous system adenosine A2A receptor expressi...
T79358	PF-07247685	Endogenous Metabolite	Metabolism
	PF-07247685是一种BCKDC激酶(BDK)抑制剂，具有较强的活性(EC50=2.2 nM)。该化合物能有效稳定BDK与BCKDH E2核心亚基之间的相互作用，并阻断E1亚基的磷酸化过程。BCKDH的活性受到BDK介导的磷酸化调控，从而控制支链氨基酸(BCAA)降解的关键步骤。BCAA的代谢失调与心力衰竭(HF)、2型糖尿病(T2DM)、非酒精性脂肪肝病(NAFLD)及肥胖等多种疾病相关联，尤其在心脏代谢疾病中表现明显。PF-07247685在小鼠模型中对心脏代谢终点产生改善效果，并提升了葡萄糖耐量。
T79357	PF-07238025	Endogenous Metabolite	Metabolism
	PF-07238025是一种BCKDC激酶(BDK)抑制剂，具有EC50值为19 nM。它通过稳定BDK和BCKDH复合体中的E2亚基相互作用，阻碍E1亚基的磷酸化过程，从而抑制了BCKDH的活性。由于BDK的磷酸化作用是控制支链氨基酸(BCAA)降解过程中的限速步骤，PF-07238025的作用与包括心力衰竭(HF)、2型糖尿病(T2DM)、非酒精性脂肪肝病(NAFLD)及肥胖在内的多种代谢性疾病的发病机制相关。研究显示PF-07238025能在小鼠体内改善心脏代谢指标并提升葡萄糖耐量。
T35890	Pentosidine	Others	Others
	Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling.[1][2] Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of ...

化合物

N-Valyltryptophan

Cat.No: T20540

Synonym: 二肽-2,Val-trp,L-Valyl-L-tryptophan

Target: Others

Glycyl-L-valine

Cat.No: T8104

Target: Others, Endogenous Metabolite

Propargylcholine

Cat.No: T38173

Synonym: Propargylcholine (bromide)

Target: Antibacterial

3-Hydroxykynurenamine Dihydrochloride

Cat.No: T68182L

Synonym: 3-OH-Kynurenamine HCl,3-Hydroxykynurenamine HCl（99362-47-7 Free base）

Target: Others

Probucol disuccinate

Cat.No: T4179

Target: LDL

Cat.No: T0128

Synonym: Sabril,Vigabatrine,氨己烯酸

Target: GABA Receptor, ABC

Xanthine oxidase-IN-1

Cat.No: T10509

Synonym: 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid

Target: Xanthine Oxidase

Cat.No: T4374

Synonym: 依度尿苷,Aedurid,EUDR,Epoxudine,乙去氧尿啶

Target: Antiviral, Antibacterial

Cat.No: T50094

Synonym: 2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid

Target: Others

Valproic acid sodium salt

Cat.No: T1602

Synonym: 丙戊酸钠,Sodium Valproate

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, HDAC, Autophagy

Cat.No: T30129

Synonym: Arg-pro

Target: Others

Cat.No: T29828

Lysyl threonine

Cat.No: T33083

Synonym: L-Threonine, l-lysyl-,Dipeptide-7,Dipeptide KT

Target: Others

Methionyltryptophan

Cat.No: T33323

Synonym: Met-trp,Methionyl-tryptophan,Methionyl tryptophan

Target: Others

Arginylphenylalanine

Cat.No: T30128

Synonym: L-Arg-L-phe

Target: Others

Cat.No: T35032

Synonym: Val-lys,Valyl-lysine

Target: Others

Cysteinyllysine

Cat.No: T31161

Target: Others

Benzylacyclouridine

Cat.No: T40932

Synonym: 5-Benzylacyclouridine,BAU

Target: Others

Cysteinyltyrosine

Cat.No: T31162

Synonym: N-L-Cysteinyl-L-tyrosine,Cys-tyr

Target: Others

6,15-diketo-13,14-dihydro Prostaglandin F1α

Cat.No: T36724

Synonym: 6,15-diketo-13,14-dihydro Prostaglandin F1α

Target: Others

Cat.No: T37809

Target: Others

Isobutyryl Coenzyme A (sodium salt)

Cat.No: T36842

Target: Others

Vigabatrin Hydrochloride

Cat.No: T0128L

Synonym: 盐酸氨己烯酸,γ-Vinyl-GABA hydrochloride

Target: GABA Receptor

L-hydroxy Arginine (acetate)

Cat.No: T35886

Cat.No: T74651

Target: Others

Cat.No: T33088

Synonym: LYS CYS,LYS-CYS,L-Cysteine, L-lysyl-,LYSCYS

Target: Others

Phenylalanylglutamate

Cat.No: T34019

Synonym: Phe-glu

Target: Others

Cat.No: T33091

Synonym: Lys-lys,L-Lys-L-lys

Target: Others

S-(p-Nitrobenzyl)glutathione

Cat.No: T81233

Target: Others

Phenylacetyl-Coenzyme A (sodium salt)

Cat.No: T37755

Target: Others

Tetrahydrouridine

Cat.No: T17059

Synonym: NSC 112907,NSC112907,四氢尿苷,NSC-112907

Target: DNA Methyltransferase

N1,N11-Diethylnorspermine

Cat.No: T60348

Target: Others

16α-Hydroxyetiocholanolone

Cat.No: T36921

Target: Others

3-Aminoisobutyric Acid sodium

Cat.No: T85123

Synonym: BAIBA,β-Aminoisobutyric Acid

Target: Others

Cat.No: T37354

Synonym: CAY10680

Target: Others

Cat.No: T79358

Target: Endogenous Metabolite

Cat.No: T79357

Target: Endogenous Metabolite

Cat.No: T35890

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2934	Bilirubin 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin	Endogenous Metabolite	Metabolism
	Bilirubin (Principal bile pigment) 是血红素分解代谢产生的黄色产物，是肝功能的重要指标。Bilirubin 具有抗诱变和抗氧化作用。
T7357	(S)-b-aminoisobutyric acid	Endogenous Metabolite	Metabolism
	(S)-b-aminoisobutyric acid 是由胸腺嘧啶和缬氨酸分解代谢得到的非蛋白质氨基酸。
T0738	Urea 尿素,Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide	Others; DHFR; Wnt/beta-catenin; Arginase; Endogenous Metabolite; Carbonic Anhydrase	Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Others; Stem Cells
	Urea (Carbonyldiamide) 在肝脏中由氨基酸脱氨产生的氨形成。它是蛋白质分解代谢的主要终代谢产物。
T4813	L-Citrulline	Endogenous Metabolite	Metabolism
	L-Citrulline 是一种氨基酸，源自于精氨酸-瓜氨酸途径获得的 l-精氨酸，或脯氨酸、谷氨酰胺和谷氨酸盐的分解代谢过程中产生的鸟氨酸。
T40490	Phenylalanylalanine H-Phe-Ala-OH,苯并氨酰丙氨酸	Others	Others
	Phenylalanylalanine（H-Phe-Ala-OH）是由苯丙氨酸和丙氨酸融合形成的二肽。它在蛋白质的不完全消化或分解过程中形成[1]。
T5253	3-Methyladipic acid	Others; Endogenous Metabolite	Metabolism; Others
	3-Methyladipic acid 是 ω 氧化途径的终产物。它是植烷酸分解代谢的代谢物。
T0626	Uric Acid 尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species; Endogenous Metabolite; Phosphorylase	Immunology/Inflammation; Metabolism; NF-κB
	Uric Acid (Lithic acid) 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ，如单线态氧和过氧亚硝酸盐，抑制脂质过氧化。Uric acid 有助于维持血压的稳定和抗氧化应激。
T19384	Isovalerylcarnitine	Apoptosis; Cysteine Protease	Apoptosis; Proteases/Proteasome
	Isovalerylcarnitine (3-methylbutyrylcarnitine) 是 L-亮氨酸分解代谢和异戊酸的积累产生的小分子化合物，也是一种具有选择性和有效性的钙蛋白酶 (calpain) 激活剂，可促使细胞凋亡，与异戊酸血症有关，可作为异戊酸血症的标志。
T4904	1-Methylguanidine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	1-Methylguanidine hydrochloride 是内源性代谢产物的一种。
TWA2417	Sodium taurocholate 牛黄胆酸钠(牛胆酸钠，牛胆酸钠盐，牛磺膽酸鈉，牛磺胆酸钠，牛磺胆酸钠盐，牛胆酸钠水合物，水合牛磺胆酸钠，牛胆酸钠(混合物)，牛黄胆酸钠(水合)，牛磺胆酸钠(标准品)),Taurocholate Sodium	Others	Others
	Sodium taurocholate (Taurocholate Sodium) hydrate 具有显著的生物学效应，例如通过上调 VEGF-A 的表达抑制肝动脉结扎所致的胆道损伤。对免疫系统具有一定的调节作用。
T5245	N-Isovaleroylglycine N-异戊酰氨基乙酸,Isovaleroylglycine,N-Isovalerylglycine	Others; Endogenous Metabolite	Metabolism; Others
	N-Isovaleroylglycine (Isovaleroylglycine) 是酰基甘氨酸，能够作为体重提高和肥胖的生物标记物。
T3578	Pyridoxal phosphate PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式，可抑制逆转录酶活性，用于研究迟发性运动障碍症。
T4909	N-Acetyl-DL-methionine N-乙酰-DL-蛋氨酸,N-乙酰-DL-甲硫氨酸	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-DL-methionine 是内源性代谢产物的一种。
T5089	5-Aminovaleric acid	Others; Endogenous Metabolite	Metabolism; Others
	5-Aminovaleric acid 被认为是 GABA 的亚甲基同系物，是GABA 的弱激动剂。它是赖氨酸降解产物。它既能够内源性产生，也能够通过赖氨酸的细菌分解代谢产生。
T4858	4-Hydroxyphenylpyruvic acid 4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid	Endogenous Metabolite	Metabolism
	4-Hydroxyphenylpyruvic acid 是一种苯丙氨酸代谢的中间产物，是一种酶抑制剂。
T20555	Glycyltyrosine NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine	Others	Others
	Glycyltyrosine, a dipeptide composed of tyrosine and glycine, is an incomplete breakdown product of protein catabolism or protein digestion.
T36563	(E)-Guggulsterone	Others	Others
	Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy...

天然产物

Cat.No: T2934

Synonym: 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin

Target: Endogenous Metabolite

(S)-b-aminoisobutyric acid

Cat.No: T7357

Target: Endogenous Metabolite

Cat.No: T0738

Synonym: 尿素,Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide

Target: Others, DHFR, Wnt/beta-catenin, Arginase, Endogenous Metabolite, Carbonic Anhydrase

Cat.No: T4813

Target: Endogenous Metabolite

Phenylalanylalanine

Cat.No: T40490

Synonym: H-Phe-Ala-OH,苯并氨酰丙氨酸

Target: Others

3-Methyladipic acid

Cat.No: T5253

Target: Others, Endogenous Metabolite

Cat.No: T0626

Synonym: 尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

Isovalerylcarnitine

Cat.No: T19384

Target: Apoptosis, Cysteine Protease

1-Methylguanidine hydrochloride

Cat.No: T4904

Target: Others, Endogenous Metabolite

Sodium taurocholate

Cat.No: TWA2417

Synonym: 牛黄胆酸钠(牛胆酸钠，牛胆酸钠盐，牛磺膽酸鈉，牛磺胆酸钠，牛磺胆酸钠盐，牛胆酸钠水合物，水合牛磺胆酸钠，牛胆酸钠(混合物)，牛黄胆酸钠(水合)，牛磺胆酸钠(标准品)),Taurocholate Sodium

Target: Others

N-Isovaleroylglycine

Cat.No: T5245

Synonym: N-异戊酰氨基乙酸,Isovaleroylglycine,N-Isovalerylglycine

Target: Others, Endogenous Metabolite

Pyridoxal phosphate

Cat.No: T3578

Synonym: PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

N-Acetyl-DL-methionine

Cat.No: T4909

Synonym: N-乙酰-DL-蛋氨酸,N-乙酰-DL-甲硫氨酸

Target: Others, Endogenous Metabolite

5-Aminovaleric acid

Cat.No: T5089

Target: Others, Endogenous Metabolite

4-Hydroxyphenylpyruvic acid

Cat.No: T4858

Synonym: 4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid

Target: Endogenous Metabolite

Cat.No: T20555

Synonym: NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine

Target: Others

(E)-Guggulsterone

Cat.No: T36563

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02151	OXCT1 Protein, Human, Recombinant (His) OXCT1,Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mito...	Human	E. coli
	Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. OXCT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.1 kDa and the accession number is P55809.
TMPJ-00473	QPRTase Protein, Human, Recombinant (His) QPRTase,QAPRTase,Nicotinate-Nucleotide Pyrophosphorylase [Ca...	Human	E. coli
	Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quin...
TMPH-02667	Galactosylceramidase Protein, Mouse, Recombinant Galactocerebroside beta-galactosidase,Galactocerebrosidase,G...	Mouse	E. coli
	Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
TMPH-03444	GCY1 Protein, S. cerevisiae, Recombinant (His) GCY1,Galactose-inducible crystallin-like protein 1,Glycerol ...	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Glycerol dehydrogenase involved in glycerol catabolism under microaerobic conditions. Has mRNA binding activity. GCY1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.1 kDa and the accession number is P14065.
TMPH-02514	APOA4 Protein, Mouse, Recombinant (His) Apolipoprotein A4,Apolipoprotein A-IV,ApoA-IV,Apo-AIV,Apoa4	Mouse	P. pastoris (Yeast)
	May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
TMPH-01404	PYGL Protein, Human, Recombinant (GST) Glycogen phosphorylase, liver form,PYGL	Human	E. coli
	Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. PYGL Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 123.9 kDa and the accession number is P06737.
TMPH-02554	BCAT2 Protein, Mouse, Recombinant (His & Myc) Bcat2,BCAT(m),Eca40,Branched-chain-amino-acid aminotransfera...	Mouse	E. coli
	Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. BCAT2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.2 kDa and the accession number is O35855.
TMPY-03972	Aspartylglucosaminidase/AGA Protein, Human, Recombinant (His) GA,AGU,ASRG,aspartylglucosaminidase	Human	HEK293 Cells
	AGA (Aspartylglucosaminidase) is an amidohydrolase enzyme involved in the catabolism of N-linked oligosaccharides of glycoproteins. This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. Diseases associated with AGA include Aspartylglucosaminuria and Lysosomal Storage Disease. An important paralog of this gene is ASRGL1.
TMPJ-01075	BDH1 Protein, Human, Recombinant (His) D-β-Hydroxybutyrate Dehydrogenase Mitochondrial,D-Beta-Hydro...	Human	E. coli
	D-Beta-Hydroxybutyrate Dehydrogenase Mitochondrial (BDH) is a member of the short-chain dehydrogenases/reductases (SDR) family. BDH is localized in the mitochondrion matrix. BDH forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific necessity for phosphatidylcholine for optimal enzymatic activity. BDH catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the 2 main ketone bodies formed during fatty acid catabolism.
TMPY-02201	Peroxiredoxin 6 Protein, Human, Recombinant (His) p29,PRX,1-Cys,HEL-S-128m,peroxiredoxin 6,NSGPx,AOP2,aiPLA2	Human	E. coli
	PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase (GPx) and iPLA2 activities，which are concomitantly increased with the expression of PRDX6. PRDX6 promoted lung tumor growth in an in vivo allograft...
TMPH-02527	ASS1 Protein, Mouse, Recombinant (His & Myc) Ass,Citrulline--aspartate ligase,Ass1,Argininosuccinate synt...	Mouse	E. coli
	One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ASS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 5...
TMPJ-00805	Apolipoprotein E/APOE Protein, Mouse, Recombinant (His) Apo-E,APOE,Apolipoprotein E	Mouse	HEK293 Cells
	Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.
TMPY-03412	GGCT Protein, Human, Recombinant (His) gamma-glutamylcyclotransferase,C7orf24,GGC,γ-glutamylcyclotr...	Human	E. coli
	GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Pseudogenes of GGCT gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 2. Alternatively spliced transcript variants...
TMPJ-00601	Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His) Apolipoprotein C2,Apolipoprotein C-II,APC2 and APOC2	Human	E. coli
	APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoprot...
TMPJ-00938	4HPPD Protein, Human, Recombinant (His) PPD,4HPPD,HPD,4-Hydroxyphenylpyruvate Dioxygenase,HPPDase,4-...	Human	E. coli
	4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in h...
TMPH-02907	Sialidase-3 Protein, Mouse, Recombinant (His) Neu3,Membrane sialidase,Ganglioside sialidase,N-acetyl-alpha...	Mouse	E. coli
	Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Displays high catalytic efficiency for gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3. Plays a role in the regulation of transmembrane signaling through the modulation of ganglioside content of the lipid bilayer and by direct interaction with sig...
TMPY-05066	IVD Protein, Mouse, Recombinant (His) 6720455E18Rik,AI463340,isovaleryl-CoA dehydrogenase,1300016K...	Mouse	Baculovirus Insect Cells
	IVD (Isovaleryl-CoA Dehydrogenase) is a Protein Coding gene. IVD is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. IVD plays an essential role in processing proteins obtained from the diet. The body breaks down proteins from food into smaller parts called amino acids. Amino acids can be further processed to provide energy for growth and development. Isovaleryl-CoA dehydrogenase helps process a particular amino acid called leucine. Specifically, isovaleryl-CoA ...
TMPY-03338	GSTZ1 Protein, Human, Recombinant (His) MAI,GSTZ1-1,glutathione S-transferase ζ 1,MAAI,GSTZ1,glutath...	Human	E. coli
	GSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein that has minimal glutathione-conjugating activity with ethacrynic acid ...
TMPJ-00533	LYVE1 Protein, Human, Recombinant (His) XLKD1,Cell Surface Retention Sequence-Binding Protein 1,Extr...	Human	HEK293 Cells
	Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention s...
TMPY-01588	ALDH7A1 Protein, Human, Recombinant (His) ATQ1,aldehyde dehydrogenase 7 family, member A1,EPD,PDE	Human	E. coli
	ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine...
TMPY-02983	LYVE1 Protein, Mouse, Recombinant (hFc) 1200012G08Rik,Lyve-1,lymphatic vessel endothelial hyaluronan...	Mouse	HEK293 Cells
	LYVE1, also known as LYVE-1, is a type I integral membrane glycoprotein. It contains 1 Link domain and is mainly expressed in endothelial cells lining lymphatic vessels. LYVE1 acts as a receptor and binds to both soluble and immobilized hyaluronan. It may function in lymphatic hyaluronan transport and have a role in tumor metastasis. LYVE1 also is a cell surface receptor on lymphatic endothelial cells that can be used as a lymphatic endothelial cell marker, and sort these cells for experimental ...
TMPY-02803	IDO2 Protein, Human, Recombinant (His) indoleamine 2,3-dioxygenase 2,INDOL1	Human	E. coli
	IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of tryptophan and other indole derivatives to kynurenines. In addition to classic IDO (IDO1), a new variant, IDO2, has recently been described. IDO2 is expressed in the liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. IDO is widely distributed in human ti...

重组蛋白

OXCT1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02151

Species: Human

Expression System: E. coli

QPRTase Protein, Human, Recombinant (His)

Cat.No: TMPJ-00473

Species: Human

Expression System: E. coli

Galactosylceramidase Protein, Mouse, Recombinant

Cat.No: TMPH-02667

Species: Mouse

Expression System: E. coli

GCY1 Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03444

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

APOA4 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02514

Species: Mouse

Expression System: P. pastoris (Yeast)

PYGL Protein, Human, Recombinant (GST)

Cat.No: TMPH-01404

Species: Human

Expression System: E. coli

BCAT2 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02554

Species: Mouse

Expression System: E. coli

Aspartylglucosaminidase/AGA Protein, Human, Recombinant (His)

Cat.No: TMPY-03972

Species: Human

Expression System: HEK293 Cells

BDH1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01075

Species: Human

Expression System: E. coli

Peroxiredoxin 6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02201

Species: Human

Expression System: E. coli

ASS1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02527

Species: Mouse

Expression System: E. coli

Apolipoprotein E/APOE Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00805

Species: Mouse

Expression System: HEK293 Cells

GGCT Protein, Human, Recombinant (His)

Cat.No: TMPY-03412

Species: Human

Expression System: E. coli

Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00601

Species: Human

Expression System: E. coli

4HPPD Protein, Human, Recombinant (His)

Cat.No: TMPJ-00938

Species: Human

Expression System: E. coli

Sialidase-3 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02907

Species: Mouse

Expression System: E. coli

IVD Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05066

Species: Mouse

Expression System: Baculovirus Insect Cells

GSTZ1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03338

Species: Human

Expression System: E. coli

LYVE1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00533

Species: Human

Expression System: HEK293 Cells

ALDH7A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01588

Species: Human

Expression System: E. coli

LYVE1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02983

Species: Mouse

Expression System: HEK293 Cells

IDO2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02803

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0229	Cortisol-1,2-d2
	Cortisol-1,2-d2 是 Cortisol 的氘代化合物。Cortisol 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
TMIJ-0193	Hydrocortisone-d4
	Hydrocortisone-d4 是 Hydrocortisone 的氘代化合物。Hydrocortisone 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
TMID-0052	Taurocholic Acid-d4 Sodium
	Taurocholic Acid-d4 Sodium 是 Taurocholic Acid Sodium 的氘代化合物。Taurocholic Acid Sodium 的 CAS 号为 145-42-6。Sodium taurocholate hydrate 具有显著的生物学效应，例如通过上调 VEGF-A 的表达抑制肝动脉结扎所致的胆道损伤。对免疫系统具有一定的调节作用。
TMID-0122	Uric acid-13C-15N2
	Uric acid-13C-15N2 是 Uric acid 的 13C 和 15 N 的标记化合物。Uric acid 的 CAS 号为 69-93-2。Uric acid 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ，如单线态氧和过氧亚硝酸盐，抑制脂质过氧化。Uric acid 有助于维持血压的稳定和抗氧化应激。

同位素标记化合物

Cortisol-1,2-d2

Cat.No: TMID-0229

Hydrocortisone-d4

Cat.No: TMIJ-0193

Taurocholic Acid-d4 Sodium

Cat.No: TMID-0052

Uric acid-13C-15N2

Cat.No: TMID-0122

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼