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Search Results for " lactate dehydrogenase "

Targets Recommended: Dehydrogenase

36

抑制剂 & 化合物

13

天然产物

11

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T15435	GSK2837808A	Dehydrogenase	Metabolism
	GSK2837808A 是一种选择性的乳酸脱氢酶A 抑制剂，对 hLDHA (IC50:2.6 nM) 和 hLDHB (IC50:43 nM)。
T11829	LDH-IN-1	Dehydrogenase	Metabolism
	LDH-IN-1 是新型的基于吡唑的人乳酸脱氢酶抑制剂，对于 LDHA 和 LDHB 的 IC50 分别为32和27 nM。
T11546	hDHODH-IN-1	Dehydrogenase	Metabolism
	hDHODH-IN-1 是有效的人二氢乳清酸脱氢酶抑制剂，显示出抗炎作用。
T22336	Galloflavin	Dehydrogenase	Metabolism
	Galloflavin 是乳酸脱氢酶抑制剂。用 Pyruvate 法得到的 Ki 为 5.46 µM (LDH-A) 以及15.06 µM (LDH-B)。它能够阻断 ATP 的生成和糖酵解，从而抑制癌细胞的增殖。
T4295	(R)-GNE-140 GNE-140	Dehydrogenase	Metabolism
	(R)-GNE-140 (GNE-140) 是 LDHA 抑制剂，能够作用于 LDHA (IC50:3 nM) 和 LDHB (IC50:3 nM)。它的活性是 S 型异构体的 18 倍。
T12438	PfDHODH-IN-1	Dehydrogenase; Parasite	Metabolism; Microbiology/Virology
	PfDHODH-IN-1 是 Leflunomide 活性代谢物的类似物，具有抗疟疾活性。它是恶性疟原虫二氢乳清酸脱氢酶抑制剂。
T76146	D-Lactate dehydrogenase	Others	Others
	D-Lactate dehydrogenase(D-LDH)为一种氧化还原酶，以NAD+或NADP+作为受体，特异性作用于供体的CH-OH基团，催化D-乳酸氧化成丙酮酸。该酶主要分布于细菌和真菌中，是生化研究中常用的酶。
T76116	L-Lactate dehydrogenase	Others	Others
	L-Lactate dehydrogenase (L-乳酸脱氢酶) 是一种氧化还原酶。L-Lactate dehydrogenase 在体内催化 NADH 将丙酮酸还原为 L-乳酸。
T3175	LDHA-IN-4 AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase	Metabolism
	LDHA-IN-4 (AZ33) 是乳酸脱氢酶 A 选择性抑制剂，IC50=0.5 μM，Kd=0.093 μM。
T5325	Nifurtimox 硝呋替莫,BAY-2502,BAY-A-2502	Dehydrogenase; Parasite	Metabolism; Microbiology/Virology
	Nifurtimox (BAY-A-2502) 是一种用于锥虫病的抗虫剂，可影响乳酸脱氢酶活性。它有潜力研究神经母细胞瘤细胞。
T64345	4-(Dimethylamino)phenol	Others	Others
	4-(Dimethylamino)phenol enhances extracellular lactate dehydrogenase (LDH) levels without significant effects on gluconeogenesis. Only when the membrane becomes permeable to LDH does 4-(Dimethylamino)phenol reduce ATP content.
T39805	LDHA-IN-3 PSTMB,1-(phenylseleno)-4-(trifluoromethyl) benzene	Dehydrogenase	Metabolism
	LDHA-IN-3 (1-(phenylseleno)-4-(trifluoromethyl) benzene) 是一种有效的非竞争性乳酸脱氢酶(LDHA) 抑制剂，IC50值为 145.2 nM。LDHA-IN-3 是一种硒苯化合物，可用于研究癌症。
T4103	(L)-Sodium lactate L-乳酸钠,Sodium L-Lactate	Others	Others
	(L)-Sodium lactate (Sodium L-Lactate) 是由乳酸脱氢酶从丙酮酸中产生的。它在无氧糖酵解过程中或增殖活跃的细胞中产生。它在人和动物的血液和肌肉液中少量存在。剧烈运动后，肌肉和血液中的乳酸浓度会增加。它也存在于肝脏、肾脏、胸腺、人羊水以及其他器官和体液中。
T77579	JC2-11	IL Receptor; Dehydrogenase; ROS; Caspase; NOD-like Receptor (NLR); AIM2	Apoptosis; Immunology/Inflammation; Metabolism; Proteases/Proteasome
	JC2-11 是一种对炎症有抑制作用的化合物。JC2-11 对含有募集结构域的蛋白质 NLRC 4、黑色素瘤 2 中缺失 (AIM 2) 和非典型 (NC) 炎症小体有抑制作用，通过破坏活性氧的产生和 caspase-1 的活性来抑制炎症小体的活化。JC2-11 减少了炎症小体中 caspase-1 (p20) 的分泌、gasdermin D (GSDMD) 的裂解、IL-1β 和乳酸脱氢酶 (LDH) 的释放。
T67946	EP2 receptor antagonist-2	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	EP2 receptor antagonist-2 (CID891729)为EP2受体拮抗剂，能够抑制PGE2诱导的EP2受体激活，并阻断由N-甲基-D-天冬氨酸(NMDA)引起的乳酸脱氢酶(LDH)释放。
T15362	FX-11 LDHA Inhibitor FX11	Dehydrogenase	Metabolism
	FX-11 (LDHA Inhibitor FX11) 是一种有效的、选择性的和竞争性的乳酸脱氢酶 A (LDHA) 的特异性抑制剂，对LDHA 的Ki 为 8 μM。FX-11 对PKM2 (丙酮酸激酶 M2)具有激活作用。FX-11 可降低 ATP 水平，诱导氧化应激和ROS 生成，可引起细胞死亡。FX-11 在淋巴瘤和胰腺癌异种移植过程中表现出抗肿瘤活性。
T27421	GNE-140 racemic GNE-140,GNE 140,GNE140	Others	Others
	GNE-140 racemic is a potent lactate dehydrogenase (LDHA) inhibitor.
T70033	NCATS-SM1440	Others	Others
	NCATS-SM1440 is a Lactate Dehydrogenase Inhibitor with Optimized Cell Activity and Pharmacokinetic Properties.
T70203	Galloflavin Potassium	Others	Others
	Galloflavin Potassium is an inhibitor of lactate dehydrogenase.
T39802	Nedosiran DCR-PHXC	Others	Others
	Nedosiran (DCR-PHXC) is a GalNAc-dsRNA conjugate designed for RNA interference (RNAi) targeting lactate dehydrogenase (LDH). It serves as a potential therapeutic option for patients with primary hyperoxaluria (PH) and end-stage renal disease (ESRD).
T13450L	GNE-140 racemate GNE-140 (racemate)	Others	Others
	GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.
T78225	3-Butynoic acid	Endogenous Metabolite	Metabolism
	3-Butynoic acid 是一种有效的酰基辅酶A脱氢酶 (acyl CoA dehydrogenase) 抑制剂，是Zn依赖性黄素酶D-乳酸脱氢酶的底物，可用于研究乳酸代谢。
T71903	Meclocycline	Others	Others
	Meclocycline is a tetracycline antibiotic with broad antimicrobial activity. Meclocycline inhibits lactate dehydrogenase (LDH) release and cell toxicity induced by expression of htt-N63-148Q, a mutant form of the huntingtin gene, without altering htt-N63-148Q protein levels in PC12 cells.
T79204	Anticancer agent 122	Others	Others
	Anticanceragent 122，作为一种hLDHA抑制剂，表现出显著的抗癌活性，主要应用于抗肿瘤研究。
T79203	Anticancer agent 121	Others	Others
	Anticanceragent 121作为一种hLDHA (人类乳酸脱氢酶 A) 抑制剂，展现出卓越的抗癌活性，适用于抗肿瘤研究。
T73994	Nedosiran sodium	Others	Others
	Nedosiran sodium 是一种靶向乳酸脱氢酶 (LDH)的 RNA 干扰剂 (RNAi)。Nedosiran sodium?可用于研究并发终末期肾病 (ESRD)的原发性高草酸尿症 (PH)。
T36498	CAY10762 CAY10762	Others	Others
	CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL; IC50= 34.1 nM).1It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 μM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol in mouse brain. 1.Castelli, R., Scalvini, L., Vacondio, F., et al.Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteinesJ. Med. Chem.63(...
T73222	LDHA-IN-5	Others	Others
	LDHA-IN-5为新型且有效的GO/LDHA双重抑制剂，旨在治疗原发性高草酸尿。
T70032	NCI-006	Others	Others
	NCI-006 is a potent new inhibitor of lactate dehydrogenase (LDH) that disrupts tumor growth in mice. LDH inhibition slows tumor growth but rapidly redirects pyruvate to support mitochondrial metabolism. Inhibiting both mitochondrial complex 1 and LDH suppresses metabolic plasticity of glycolytic tumors in vivo, significantly prolonging tumor growth inhibition.
T61898	RS6212	Others	Others
	RS6212 是一种特异性乳酸脱氢酶 (LDH) 抑制剂（IC50= 12.03 μM）。RS6212 在多种癌细胞系中显示出强大的抗癌活性。
T82373	FPR2 agonist 3	Others	Others
	FPR2 agonist 3 能够抑制 LPS 刺激下的培养物中乳酸脱氢酶的释放，并减少促炎性因子IL-1β和IL-6的表达水平。此外，FPR2 agonist 3 还可以通过作用于 STAT3/SOCS3 信号通路来降低 STAT3 的磷酸化水平。
T61312	Antioxidant agent-3	Others	Others
	Antioxidant agent-3 (Compound 14q) 是一种抗氧化剂，具有有效的DPPH 自由基清除活性和ABTS+清除活性，IC50分别为 26.58 和 30.31 μM。Antioxidant agent-3 作用于 H2O2处理的 HepG2 细胞，可增加活性氧 (ROS)、超氧化物歧化酶 (SOD) 和谷胱甘肽 (GSH)，并减少乳酸脱氢酶(LDH)。
T72017	6(5H)-Phenanthridinone	Others	Others
	6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes. In vivo, 6(5H)-phenanthridinone reduces spinal cord expression of inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of experimenta...
T37671	CAY10608 CAY10608	Others	Others
	N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. CAY10608 is a propanolamine that potently, selectively, and non-competitively antagonizes the NR2B subunit of NMDA receptors (IC50 = 50 nM). It does not inhibit NR1, NR2A, NR2C, and NR2D subunits and has no significant effects on α-amino-3-hydroxy-5-methyl-4-isoxazolepropioinic acid (AMPA) or kainate receptors. CAY...
T36610	(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine	Others	Others
	(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities. It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM). CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis. It reverses hydrogen peroxide-induced release of malondialdehyde ...
T83768	Zofenoprilat Zofenopril-SH,SQ 26,333	Others	Others
	Zofenoprilat是一种血管紧张素转换酶(ACE; IC50 = 8 nM for the rabbit lung enzyme)的抑制剂，同时也是前体药zofenopril的活性代谢产物。它能够抑制分离的豚鼠小肠中由血管紧张素I或缓激肽诱导的收缩(EC50s = 3 and 1 nM, respectively)。在人类脐静脉内皮细胞(HUVECs)中，Zofenoprilat (10 nM)降低基础内皮素-1分泌和一氧化氮(NO)生成，并阻止TNF-α诱导的活性氧种(ROS)增加以及谷胱甘肽(GSH)水平降低。Zofenoprilat (10 µM)保护初级人类心脏微血管内皮细胞免受多柔比星诱导的细胞毒性。此外，Zofenoprilat (10 µM)还能增加HUVECs中的硫化氢(H2S)生成，以及细胞的黏着、迁移和增殖。在以400 µM浓度使用时，它可以减少Langendorff分离的大鼠心脏灌流缺血再灌注损伤模型中的舒张末压和乳酸脱氢酶(LDH)释放。

化合物

Cat.No: T15435

Target: Dehydrogenase

Cat.No: T11829

Target: Dehydrogenase

Cat.No: T11546

Target: Dehydrogenase

Cat.No: T22336

Target: Dehydrogenase

Cat.No: T4295

Synonym: GNE-140

Target: Dehydrogenase

Cat.No: T12438

Target: Dehydrogenase, Parasite

D-Lactate dehydrogenase

Cat.No: T76146

Target: Others

L-Lactate dehydrogenase

Cat.No: T76116

Target: Others

Cat.No: T3175

Synonym: AZ 33,AZ-33,LDHA Inhibitor,AZ33

Target: Dehydrogenase

Cat.No: T5325

Synonym: 硝呋替莫,BAY-2502,BAY-A-2502

Target: Dehydrogenase, Parasite

4-(Dimethylamino)phenol

Cat.No: T64345

Target: Others

Cat.No: T39805

Synonym: PSTMB,1-(phenylseleno)-4-(trifluoromethyl) benzene

Target: Dehydrogenase

(L)-Sodium lactate

Cat.No: T4103

Synonym: L-乳酸钠,Sodium L-Lactate

Target: Others

Cat.No: T77579

Target: IL Receptor, Dehydrogenase, ROS, Caspase, NOD-like Receptor (NLR), AIM2

EP2 receptor antagonist-2

Cat.No: T67946

Target: Prostaglandin Receptor

Cat.No: T15362

Synonym: LDHA Inhibitor FX11

Target: Dehydrogenase

GNE-140 racemic

Cat.No: T27421

Synonym: GNE-140,GNE 140,GNE140

Target: Others

Cat.No: T70033

Target: Others

Galloflavin Potassium

Cat.No: T70203

Target: Others

Cat.No: T39802

Synonym: DCR-PHXC

Target: Others

GNE-140 racemate

Cat.No: T13450L

Synonym: GNE-140 (racemate)

Target: Others

3-Butynoic acid

Cat.No: T78225

Target: Endogenous Metabolite

Cat.No: T71903

Target: Others

Anticancer agent 122

Cat.No: T79204

Target: Others

Anticancer agent 121

Cat.No: T79203

Target: Others

Nedosiran sodium

Cat.No: T73994

Target: Others

Cat.No: T36498

Synonym: CAY10762

Target: Others

Cat.No: T73222

Target: Others

Cat.No: T70032

Target: Others

Cat.No: T61898

Target: Others

Cat.No: T82373

Target: Others

Antioxidant agent-3

Cat.No: T61312

Target: Others

6(5H)-Phenanthridinone

Cat.No: T72017

Target: Others

Cat.No: T37671

Synonym: CAY10608

Target: Others

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

Cat.No: T36610

Target: Others

Cat.No: T83768

Synonym: Zofenopril-SH,SQ 26,333

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5705	Glomeratose A	Dehydrogenase	Metabolism
	Glomeratose A 是分离自远志Polygala tenuifolia 中，是一种乳酸脱氢酶lactate dehydrogenase 抑制剂。
T7964	Isomalt 异麦芽酮糖醇,Palatinitol,Palatinit	Others; Dehydrogenase	Metabolism; Others
	Isomalt (Palatinitol) 是无毒的、具有良好耐受性的多元醇和蛋白质稳定的赋形剂，在冷冻干燥过程中可适度稳定乳酸脱氢酶(LDH)，并在储存期间表现更好。它传统上在食品工业中用作甜味剂，也在制药中用作压片赋形剂。
T5S0620	3-Dehydrotrametenolic acid Dehydrotrametenolic acid,松苓新酸,3-氢化去氢松苓酸	Apoptosis; Others; Dehydrogenase	Apoptosis; Metabolism; Others
	3-Dehydrotrametenolic acid 是从茯苓菌核分离的一种乳酸脱氢酶抑制剂，可诱导细胞凋亡，具有抗癌活性。它促进体外脂肪细胞分化，在体内起胰岛素增敏剂的作用。
T4738	Sodium 2-hydroxybutanoate 2-Hydroxybutyric acid sodium salt,2-羟基丁酸钠,DL-2-Hydroxybutyric Acid Sodium Salt,alpha-hydroxybutyrate,SODIUM 2-HYDROXYBUTYRATE	Others; Endogenous Metabolite	Metabolism; Others
	Sodium 2-hydroxybutanoate (alpha-hydroxybutyrate) 是内源性代谢产物的一种。
TN1829	Kakkalide	Dehydrogenase	Metabolism
	Kakkalide 是提取自葛根花中的一种异黄酮。它可以抑制活性氧相关炎症，并改善内皮细胞胰岛素抵抗作用。
T5S2195	Sibiricose A5 西伯利亚远志糖A5	Dehydrogenase	Metabolism
	Sibiricose A5 是一种寡糖酯，分离自Polygalae Radix，具有抗氧化作用。
T2S2211	Tenuifoliside C	Dehydrogenase	Metabolism
	Tenuifoliside C 是从野生的 polygala tenuifolia 中分离得到的。它对 CYP2E1 催化氯唑酮 6-羟基化反应具有抑制作用。
TN1769	Iristectorin A	Dehydrogenase	Metabolism
	Iristectorin A 是从 Iris tectorum Maxim 中提取出来的异黄酮化合物，是一种乳酸脱氢酶抑制剂，可用于研究癌症。
T5702	Tenuifoliside B	Dehydrogenase	Metabolism
	Tenuifoliside B 是一种分离自Polygalae Radix 中的成分，能够抑制氰化钾引起的缺氧和东莨菪碱引起的记忆障碍。它有成为 AD 先导化合物的潜力。它具有潜在的认知改善和脑保护作用。
TN1182	11-Keto-beta-boswellic acid 11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸	Leukotriene Receptor; NF-κB; Lipoxygenase	GPCR/G Protein; Metabolism; NF-κB
	11-Keto-beta-boswellic acid 是来自乳香的一种五环三萜酸，具有抗炎活性和剂量依赖性心脏保护作用，主要是由于抑制5-脂氧合酶、白三烯、NF-κB 的激活和肿瘤坏死因子 α 的产生。
T5290	(S)-2-Hydroxy-3-phenylpropanoic acid L-(−)-3-Phenyllactic acid,L-3-苯乳酸	Others; Endogenous Metabolite	Metabolism; Others
	(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) 是苯丙氨酸的代谢产物。苯丙酮尿症患者体液中苯丙氨酸的水平升高。
T13922	Thevetiaflavone 2-Genistein-5-methyl ether,Apigenin-5-methyl ether	BCL; Caspase	Apoptosis; Proteases/Proteasome
	Thevetiaflavone (2-Genistein-5-methyl ether) 是一种来自 Wikstroemia indica 的天然类黄酮，可抑制乳酸脱氢酶从细胞质中泄漏并提高细胞活力。
T83725	Nigerose Sakebiose	Others	Others
	Nigerose，一种在Acremonium中发现的二糖，当与苷类化合物salidroside联合使用，浓度为150 µM时，可阻止HL-60细胞冷冻保存后的丙二醛（MDA）和活性氧物质（ROS）水平上升，并抑制乳酸脱氢酶（LDH）的释放。

天然产物

Cat.No: T5705

Target: Dehydrogenase

Cat.No: T7964

Synonym: 异麦芽酮糖醇,Palatinitol,Palatinit

Target: Others, Dehydrogenase

3-Dehydrotrametenolic acid

Cat.No: T5S0620

Synonym: Dehydrotrametenolic acid,松苓新酸,3-氢化去氢松苓酸

Target: Apoptosis, Others, Dehydrogenase

Sodium 2-hydroxybutanoate

Cat.No: T4738

Synonym: 2-Hydroxybutyric acid sodium salt,2-羟基丁酸钠,DL-2-Hydroxybutyric Acid Sodium Salt,alpha-hydroxybutyrate,SODIUM 2-HYDROXYBUTYRATE

Target: Others, Endogenous Metabolite

Cat.No: TN1829

Target: Dehydrogenase

Cat.No: T5S2195

Synonym: 西伯利亚远志糖A5

Target: Dehydrogenase

Tenuifoliside C

Cat.No: T2S2211

Target: Dehydrogenase

Cat.No: TN1769

Target: Dehydrogenase

Tenuifoliside B

Cat.No: T5702

Target: Dehydrogenase

11-Keto-beta-boswellic acid

Cat.No: TN1182

Synonym: 11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸

Target: Leukotriene Receptor, NF-κB, Lipoxygenase

(S)-2-Hydroxy-3-phenylpropanoic acid

Cat.No: T5290

Synonym: L-(−)-3-Phenyllactic acid,L-3-苯乳酸

Target: Others, Endogenous Metabolite

Thevetiaflavone

Cat.No: T13922

Synonym: 2-Genistein-5-methyl ether,Apigenin-5-methyl ether

Target: BCL, Caspase

Cat.No: T83725

Synonym: Sakebiose

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04180	PfLDH Protein, P. falciparum, Recombinant (His) PfLDH,L-lactate dehydrogenase	P. falciparum	E. coli
	Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy.
TMPH-03136	L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc) LDH,L-lactate dehydrogenase	Plasmodium berghei	E. coli
	N/A. L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is Q7SI97.
TMPH-00693	L-lactate dehydrogenase Protein, E. coli O9:H4, Recombinant (His) lldD,L-lactate dehydrogenase	E. coli	E. coli
	Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
TMPY-04241	LDHA Protein, Rat, Recombinant (His) lactate dehydrogenase A	Rat	E. coli
	LDHA Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 38.7 kDa and the accession number is B5DEN4.
TMPY-00010	LDHA Protein, Mouse, Recombinant (His) Ldh1,lactate dehydrogenase A,Ldhm,l7R2	Mouse	E. coli
	LDHA Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P06151.
TMPJ-00797	LDHB Protein, Human, Recombinant (His) LDH-B,Renal Carcinoma Antigen NY-REN-46,LDH-H,LDH Heart Subu...	Human	E. coli
	L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver....
TMPH-01614	LDHC Protein, Human, Recombinant (His & SUMO) LDH-X,L-lactate dehydrogenase C chain,Canc...	Human	E. coli
	Possible role in sperm motility.
TMPJ-00724	LDHA Protein, Human, Recombinant (His) LDH-M,Renal Carcinoma Antigen NY-REN-59,Cell Proliferation-I...	Human	E. coli
	L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
TMPY-04826	LILRB5/CD85c Protein, Human, Recombinant (His) leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C	Human	HEK293 Cells
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-05186	LILRB5/CD85c Protein, Human, Recombinant (His), Biotinylated LIR-8,LIR8,leukocyte immunoglobulin like receptor B5,CD85C	Human	HEK293 Cells
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted ...
TMPY-06273	LILRB5/CD85c Protein, Human, Recombinant (hFc) LIR-8,LIR8,CD85C,leukocyte immunoglobulin like receptor B5	Human	HEK293 Cells
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weig...

重组蛋白

PfLDH Protein, P. falciparum, Recombinant (His)

Cat.No: TMPY-04180

Species: P. falciparum

Expression System: E. coli

L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc)

Cat.No: TMPH-03136

Species: Plasmodium berghei

Expression System: E. coli

L-lactate dehydrogenase Protein, E. coli O9:H4, Recombinant (His)

Cat.No: TMPH-00693

Species: E. coli

Expression System: E. coli

LDHA Protein, Rat, Recombinant (His)

Cat.No: TMPY-04241

Species: Rat

Expression System: E. coli

LDHA Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00010

Species: Mouse

Expression System: E. coli

LDHB Protein, Human, Recombinant (His)

Cat.No: TMPJ-00797

Species: Human

Expression System: E. coli

LDHC Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01614

Species: Human

Expression System: E. coli

LDHA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00724

Species: Human

Expression System: E. coli

LILRB5/CD85c Protein, Human, Recombinant (His)

Cat.No: TMPY-04826

Species: Human

Expression System: HEK293 Cells

LILRB5/CD85c Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05186

Species: Human

Expression System: HEK293 Cells

LILRB5/CD85c Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06273

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T71305	Clofibric Acid-d4
	Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxal...

同位素标记化合物

Clofibric Acid-d4

Cat.No: T71305

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