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GNE-140 racemate
还可以产品编号 T13450LCas号 1802977-61-2
别名 GNE-140 (racemate)
GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.
GNE-140 racemate
还可以产品编号 T13450L 别名 GNE-140 (racemate)Cas号 1802977-61-2
GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 2,130 | 5日内发货 | |
| 5 mg | ¥ 2,890 | 5日内发货 | |
| 10 mg | ¥ 4,160 | 5日内发货 | |
| 1 mL x 10 mM (in DMSO) | ¥ 3,190 | 5日内发货 |
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生物活性
化学信息
| 产品描述 | GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. |
| 体外活性 | Lactate dehydrogenase A (LDHA) is a key glycolytic enzyme and is also a hallmark of aggressive cancers. Which believed to be the major enzyme responsible for the pyruvate-to-lactate conversion. Because of increased glycolysis, increased glucose consumption distinguishes cancer cells from normal cells and is known as the 'Warburg effect”[1]. |
| 别名 | GNE-140 (racemate) |
| 分子量 | 499.04 |
| 分子式 | C25H23ClN2O3S2 |
| CAS No. | 1802977-61-2 |
| 密度 | 1.43 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| 溶解度信息 | DMSO: 34 mg/mL (68.13 mM) | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
DMSO
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体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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