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血小板源生长因子 (Platelet-Derived Growth Factors, PDGFs)

血小板衍生生长因子(PDGF)是调节细胞生长和分裂的众多生长因子之一。特别是,PDGF在血管形成、现有血管组织中的血管生长、间充质细胞的有丝分裂发生以及间充质细胞的趋化性中起着重要作用。血小板源生长因子是一种二聚体糖蛋白,可以由两个 A 亚基 (PDGF-AA)、两个 B 亚基 (PDGF-BB) 或各一个 (PDGF-AB) 组成。PDGF有五种不同的亚型,它们通过两种不同的受体激活细胞反应。已知配体包括:PDGF-AA (PDGFA)、-BB (PDGFB)、-CC (PDGFC) 和 -DD (PDGFD) 以及 -AB (PDGFA 和 PDGFB 异二聚体)。配体与两种酪氨酸激酶受体单体PDGFRα(PDGFRA)和-Rβ(PDGFRB)相互作用。重组PDGF在医学上用于帮助治愈慢性溃疡,在骨科手术和牙周病学中作为骨自体移植的替代品,以刺激骨再生和修复。

PDGF-BB Protein, Human, Recombinant
TMPJ-00735
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
  • ¥ 1170
现货
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PDGF-AA Protein, Human, Recombinant
TMPJ-00767
PDGF-AA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P04085.
  • ¥ 1170
5日内发货
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PDGF-BB Protein, Mouse, Recombinant (His)
TMPJ-00562
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor,it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing.
  • ¥ 810
现货
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PDGFC Protein, Cynomolgus, Recombinant (hFc)
TMPY-00269
PDGFC Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is G7P6G9.
  • ¥ 3930
5日内发货
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PDGFA Protein, Human, Recombinant (His)
TMPY-05056
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 16.3 kDa and the accession number is AAA60045.1.
  • ¥ 2940
5日内发货
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PDGFB Protein, Cynomolgus, Recombinant (mFc)
TMPY-02395
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 38.9 kDa and the accession number is G7PFK7.
  • ¥ 4420
5日内发货
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PDGFB Protein, Human, Recombinant (His)
TMPY-04644
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P01127-2.
  • ¥ 3820
现货
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PDGFA Protein, Mouse, Recombinant (His)
TMPY-04838
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.5 kDa and the accession number is Q99L56.
  • ¥ 3820
5日内发货
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PDGFC Protein, Mouse, Recombinant (His)
TMPY-04976
PDGFC Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.4 kDa and the accession number is Q8CI19.
  • ¥ 3930
现货
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PDGFB Protein, Rhesus, Recombinant (His)
TMPY-05077
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Rhesus, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.2 kDa and the accession number is A0A1D5Q4I7.
  • ¥ 3430
5日内发货
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PDGFD Protein, Cynomolgus, Recombinant (His)
TMPK-01178
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, including proliferation, migration, adhesion and tube formation, and thereby contributes to angiogenesis.
  • ¥ 3100
5日内发货
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PDGFD Protein, Mouse, Recombinant (His & SUMO)
TMPH-02835
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
  • ¥ 1800
20日内发货
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PDGFA Protein, Rat, Recombinant (His)
TMPY-05068
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.5 kDa and the accession number is AAB26134.2.
  • ¥ 3170
5日内发货
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PDGFB Protein, Canine, Recombinant (His)
TMPY-05076
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q6Q7I7.
  • ¥ 3430
5日内发货
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PDGFA Protein, Canine, Recombinant (His)
TMPY-05075
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.5 kDa and the accession number is A0A8C0M6T8.
  • ¥ 2940
5日内发货
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PDGF-AA Protein, Human, Recombinant (His)
TMPJ-00768
PDGF-AA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is P04085.
  • ¥ 1170
5日内发货
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PDGFA Protein, Canine, Recombinant (hFc)
TMPY-00455
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is A0A8C0M6T8.
  • ¥ 3430
5日内发货
规格
数量
PDGFB Protein, Mouse, Recombinant (His)
TMPY-04877
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.2 kDa and the accession number is Q8R3X9.
  • ¥ 2440
5日内发货
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PDGFC Protein, Human, Recombinant (His)
TMPY-02815
PDGFC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13.89 kDa and the accession number is Q9NRA1-1.
  • ¥ 2940
5日内发货
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PDGFC Protein, Human, Recombinant (hFc)
TMPY-00898
PDGFC Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is Q9NRA1-1.
  • ¥ 3930
5日内发货
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PDGFC Protein, Mouse, Recombinant (hFc)
TMPY-02251
PDGFC Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q8CI19.
  • ¥ 3930
5日内发货
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数量