羽扇豆属

Angustifoline 是一种具有抗菌和抗癌活性的生物碱。作为提取自狭叶狼疮（Lupinus angustifolius L.）的天然产物对多种细菌（如金黄色葡萄球菌、枯草芽孢杆菌、大肠杆菌等）有抑制作用，还能通过诱导自噬和凋亡，抑制人结肠癌细胞的生长，侵袭和迁移。

Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokines and blocking of IFN-β STAT1 pathw

Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.

Lupanine（羽扇豆碱，(+)-Lupanine）是一种天然的喹唑啉生物碱，能够有效的亲和并激活烟碱型乙酰胆碱受体（nAChR）（Ki=500 nM），在细胞模型中对可溶性淀粉样β寡聚物（SO-Aβ）的毒性表现出显著的神经保护效果，与抗凋亡的PI3K Akt Bcl-2信号通路有关，具有抗阿尔茨海默病潜力。通过影响KATP通道和增强胰岛素分泌改善葡萄糖稳态,具有治疗2 型糖尿病的潜能。

Eriosemation significant androgen receptor (AR) inhibition activity, suggests that it could be a promising candidate for further evaluation for prostate cancer prevention or management.

2'-Hydroxygenistein是一种天然的黄酮，具有抗氧化、抗炎、抗癌、抗子宫内膜增生等多种潜力。2'-羟基金雀异黄素是多种酶抑制剂，包括吲哚-3-乙酸氧化酶、α-葡萄糖苷酶、β-葡萄糖醛酸酶和溶菌酶。

6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.

Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug disc. Sophoraisoflavone A shows inhibitory effects on copper-induced prot

Topazolin has weak fungitoxic activity, it displays significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 ug mL, it also shows in vitro free radical scavenging activities with IC50 values in the range of 0.18-0.56 mg mL.