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TMPH-02569
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WISP2/CCN5 Protein, Mouse, Recombinant (His)
Ccn5,Connective tissue growth factor-like protein,CCN family...
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Mouse
|
P. pastoris (Yeast)
|
|
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. |
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TMPH-02889
|
Spp-24 Protein, Mouse, Recombinant (His & Myc)
Secreted phosphoprotein 24,Spp2,Secreted phosphoprotein 2
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Mouse
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E. coli
|
|
Could coordinate an aspect of bone turnover. |
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TMPH-01063
|
Cathepsin O Protein, Human, Recombinant (His & Myc)
CTSO1,CTSO,Cathepsin O
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Human
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HEK293 Cells
|
|
Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. Cathepsin O Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 28.5 kDa and the accession number is P43234. |
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TMPH-03032
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Leucyl aminopeptidase Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)
Probable cytosol aminopeptidase,Leucine aminopeptidase,Leucy...
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Mycoplasma pneumoniae
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E. coli
|
|
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Leucyl aminopeptidase Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 64.8 kDa and the accession number is P75206. |
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TMPH-02570
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WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)
CCN family member 5,Connective tissue growth factor-like pro...
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Mouse
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E. coli
|
|
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. |
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TMPH-01059
|
Cathepsin B Protein, Human, Recombinant (GST)
Cathepsin B1,APPS,Cathepsin B,CPSB,APP secretase,CTSB
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Human
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E. coli
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|
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. Cathepsin B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.6 kDa and the accession number is P07858. |
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TMPH-01062
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Cathepsin O Protein, Human, Recombinant (E. coli, His & Myc)
CTSO1,CTSO,Cathepsin O
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Human
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E. coli
|
|
Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. Cathepsin O Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.5 kDa and the accession number is P43234. |
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TMPK-00237
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2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated
NAIL,CD244,SLAMF4,h2B4,NKR2B4,Nmrk,CD244 antigen,2B4
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Human
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HEK293 Cells
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|
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness. |
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TMPH-01714
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CHRM1 Protein, Human, Recombinant (His)
Muscarinic acetylcholine receptor M1,CHRM1
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Human
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E. coli
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|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.8 kDa and the accession number is P11229. |
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TMPH-01060
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Cathepsin F Protein, Human, Recombinant (His)
Cathepsin F,CTSF,CATSF
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Human
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E. coli
|
|
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Cathepsin F Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is Q9UBX1. |
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TMPJ-00989
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MTHFS Protein, Human, Recombinant (His)
5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydro...
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Human
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E. coli
|
|
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increas... |
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TMPH-03338
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CHRM1 Protein, Rat, Recombinant (His)
Muscarinic acetylcholine receptor M1,CHRM1
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Rat
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E. coli
|
|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.1 kDa and the accession number is P08482. |
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TMPH-01717
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CHRM5 Protein, Human, Recombinant (His)
CHRM5,Muscarinic acetylcholine receptor M5
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Human
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E. coli
|
|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.5 kDa and the accession number is P08912. |
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TMPY-03990
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Profilin 4 Protein, Human, Recombinant (His)
profilin family, member 4
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Human
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E. coli
|
|
PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilaments. Profilin is one of the most abundant actin monomer binders, but proteins such as CAP and (in mammals) thymosin β4 have some functional overlaps with profilin. In contrast, ADF/cofilin has some properties that antagonize profilin action. PFN4 also functions in the dynamic turn... |
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TMPH-01716
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CHRM3 Protein, Human, Recombinant (B2M & His)
Muscarinic acetylcholine receptor M3,CHRM3
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Human
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E. coli
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The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM3 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 40.7 kDa and the accession number is P20309. |
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TMPJ-00823
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UBB Protein, Human, Recombinant
UBB,Polyubiquitin-B
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Human
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E. coli
|
|
Polyubiquitin-B(UBB) is one of Ubiquitins. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. |
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TMPJ-00839
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ODC1 Protein, Human, Recombinant (His)
ODC1,Ornithine decarboxylase
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Human
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E. coli
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Ornithine decarboxylase (ODC1) is an enzyme which belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC1 is the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. |
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TMPH-00867
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ADAMTS4 Protein, Human, Recombinant (GST)
ADAMTS-14,ADAM-TS 14,A disintegrin and metalloproteinase wit...
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Human
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E. coli
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|
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. ADAMTS4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 39.0 kDa and the accession number is O75173. |
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TMPH-03195
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Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc)
Protein archease
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Pyrococcus horikoshii
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E. coli
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Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.1 kDa and the accession number is O59205... |
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TMPJ-00046
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IL-17F Protein, Human, Recombinant
IL17F,白介素,IL-17F,Interleukin-17F,白细胞介素,Cytokine ML-1
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Human
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E. coli
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Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage mat... |
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TMPH-01624
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GBA Protein, Human, Recombinant
Lysosomal glycosylceramidase,Acid beta-glucosidase,Alglucera...
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Human
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E. coli
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Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... |
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TMPJ-00508
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CTSL Protein, Human, Recombinant (His)
CTSL,CTSL1,Cathepsin L1,Major Excreted Protein,MEP
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Human
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HEK293 Cells
|
|
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the maj... |
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TMPY-03751
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C1orf33/MRTO4 Protein, Human, Recombinant (His)
MRT4,dJ657E11.4,C1orf33,MRT4 homolog, ribosome maturation fa...
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Human
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E. coli
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MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. MRTO4 is a nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. The precise function of MRTO4 is c... |
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TMPY-04269
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LAP3 Protein, Human, Recombinant (His)
HEL-S-106,leucine aminopeptidase 3,PEPS,LAP,LAPEP
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Human
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HEK293 Cells
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|
LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. 2 alternative initiation human isoforms have been reported. LAP3, belonging to the peptidase M17 family, has been proved to catalyze the hydrolysis of leucine residues. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides and is presumably involved in the processing and regular turnover of intracellular proteins. Leucine aminopeptidases are involved in many pathological disorders and regulate cell prolife... |
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TMPY-02522
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OTUB2 Protein, Human, Recombinant (His)
OTU deubiquitinase, ubiquitin aldehyde binding 2,OTU2,OTB2,C...
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Human
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E. coli
|
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Otubain 2 (OTUB2) is a member of DUBs that belong to the ovarian tumour (OTU) superfamily of proteins which consists of a five-stranded β-sheet sandwiched in between a small helical amino-terminal region consisting of α1 and α2, and a large helical region comprised of α3-α10. Like other DUBs, otubain 2 (OTUB2) cleaves proteins precisely at the ubiquitin-protein bond so that ubiquitylation process can be reversed and regulated. Otubain 2 (OTUB2)'s active-site cleft is sterically occluded by a nov... |
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TMPH-01623
|
GBA Protein, Human, Recombinant (His & Myc & SUMO)
Lysosomal acid glucosylceramidase,GBA1,Lysosomal galactosylc...
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Human
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E. coli
|
|
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... |
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TMPY-02214
|
OTUB1 Protein, Human, Recombinant (His)
OTU deubiquitinase, ubiquitin aldehyde binding 1,OTB1,HSPC26...
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Human
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E. coli
|
|
Ubiquitin thioesterase OTUB1, also known as Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, Ubiquitin-specific-processing protease OTUB1, OTUB1 and OTB1, is a cytoplasm protein that belongs to the peptidase C65 family. OTUB1 is a hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. OTUB1 is a regulator of T-cell anergy, a phenomenon that... |
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TMPY-02843
|
GPX7 Protein, Human, Recombinant (hFc)
GSHPx-7,UNQ469/PRO828,NPGPx,CL683,glutathione peroxidase 7,G...
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Human
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HEK293 Cells
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|
GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to differ by overlapping exons with different boundaries. GPX7 is an enzyme. It has molecular functions (glutathione peroxidase activity, oxidoreductase activity) and to localize in various compartments (extracellular space, extracellular region). GPX7 gene has been proposed to part... |
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TMPY-00732
|
Cathepsin C Protein, Human, Recombinant (His)
DPP-I,PLS,JP,cathepsin C,CPPI,DPPI,PDON1,PALS,DPP1,JPD,HMS
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Human
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HEK293 Cells
|
|
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c... |
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TMPH-01664
|
OMA1 Protein, Human, Recombinant (His & SUMO)
Overlapping with the m-AAA protease 1 homolog,OMA1,Metallopr...
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Human
|
E. coli
|
|
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OPA1, UQCC3 and DELE1. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Also acts as a regulator of apoptosis: upon BAK and BAX ag... |
|
TMPY-01826
|
Relaxin 1/RLN1 Protein, Human, Recombinant (His)
RLXH1,H1RLX,relaxin 1,bA12D24.3.1,H1,RLN1,bA12D24.3.2
|
Human
|
HEK293 Cells
|
|
Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductive hormone 8 years ago, relaxin has been implicated in a number of pregnancy-related functions involving extracellular matrix (ECM) turnover and collagen degradation. It is now becoming evident that relaxin's ability to reduce matrix synthesis and increase ECM degradation has impo... |
|
TMPY-02150
|
GADD45A Protein, Human, Recombinant (His & GST)
GADD45,growth arrest and DNA-damage-inducible, alpha,growth ...
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Human
|
Baculovirus Insect Cells
|
|
GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulation, DNA repair and genomic stability, apoptosis, and immune responses. The GADD45 Family of genes is rapidly induced by different stressors, including differentiation-inducing cytokines, and there is a large body of evidence that their cognate proteins are key players in cellular ... |
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TMPH-02841
|
Prohibitin Protein, Mouse, Recombinant (His)
Phb1,B-cell receptor-associated protein 32,Prohibitin 1
|
Mouse
|
E. coli
|
|
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with... |
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