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Search Results for " triterpenoid "

Targets Recommended: Immunology/Inflammation related

37

抑制剂 & 化合物

105

天然产物

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T124663	Sericoside	Immunology/Inflammation related	Immunology/Inflammation
	Sericoside，一种从Terminalia提取的三萜类化合物，具备显著的抗炎特性。此外，sericoside展现出强效的解脂活性，有助于减少皮肤皱纹及改善肤质。
T6919	Omaveloxolone RTA-408	Apoptosis; Others; Nrf2; STING	Apoptosis; Immunology/Inflammation; Others
	Omaveloxolone (RTA-408) 是一种抗氧化炎症调节剂，可激活Nrf2并抑制一氧化氮。它通过抑制 STING 依赖的 NF-κb 信号通路，来抑制破骨细胞的生成。
T6165	Bardoxolone Methyl RTA 402,CDDO Methyl ester,TP-155,甲基巴多索隆,NSC 713200	Apoptosis; IκB/IKK; Ferroptosis; Nrf2; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; NF-κB
	Bardoxolone Methyl (TP-155) 是一种合成的三萜类化合物，作为 Nrf2通路的激活剂和 NF-κB 途径的抑制剂，具有潜在的抗肿瘤和抗炎活性。
T13604	CDDO-dhTFEA	Others; NF-κB; Nrf2	Immunology/Inflammation; NF-κB; Others
	CDDO-dhTFEA 是合成的齐墩果烷三萜化合物，可有效激活Nrf2并抑制促炎转录因子NF-κB。它可以恢复高血压 (MAP)，提高 Nrf2 及其靶基因的表达，抑制 NF-κB 的活化和转化生长因子-β 途径，并减少慢性肾病 (CKD) 大鼠的肾小球硬化，间质纤维化和炎症。
T34516	Sapelin B NSC 270047,NSC270047,NSC-270047	Others	Others
	Sapelin B is a triterpenoid.
T34437	Rubiatriol	Others	Others
	Rubiatriol is a triterpenoid isolated from the root of Rubia cordifolia L.
T26056	Regelinol	Others	Others
	Regelinol is a new antitumor ursene-type triterpenoid isolated from Tripterygium regelii.
T32325	Justicisaponin I	Others	Others
	Justicisaponin I is a type of triterpenoid saponin from Justicia simplex D. Don. (Acanthaceae).
T33627	Nematocyphol	Others	Others
	Nematocyphol is a triterpenoid from Euphorbia nematocypha hand-mazz.
T33335	Methyl adenophorate	Others	Others
	Methyl adenophorate is a triterpenoid of Adenophora triphylla var. japonica roots.
T32565	Lantaiursolic acid	Others	Others
	Lantaiursolic acid is a triterpenoid extracted from the roots of Lantana camara.
TP2438	Sarasinoside B1 Sarasinoside-B1
	Sarasinoside B1 is a norlanostane-triterpenoid oligoglycoside from the Palauan marine sponge Asteropus sarasinosum.
T34574	Schisandronic acid Schizandronic acid,Ganwuweizic acid	Others	Others
	Schisandronic acid is a triterpenoid acid isolated from the stems of Schisandra propinqua.
TP2436	Saniculoside R 1 Saniculoside R-1
	Saniculoside R 1 is a new triterpenoid saponin from Sanicula europaea.
T20613	Inotodiol	Others	Others
	Inotodiol is an included triterpenoid with a significant effect of anti-tumor.
T32203	Isobauerenol (+)-Isobauerenol	Others	Others
	Isobauerenol is a triterpenoid compound isolated from sterile stems.
T32044	Hancolupenol	Others	Others
	Hancolupenol is a novel triterpenoid compound derived from Cyanchum hancockianum.
T32566	Lantanolic acid	Others	Others
	Lantanolic acid is a pentacyclic triterpenoid from the leaves of Lantana montevidensis.
T37781	2,3-Indolobetulin	Others	Others
	2,3-Indolobetulin is a pentacyclic triterpenoid and derivative of betulin .1It has been used in the synthesis of α-glucosidase inhibitors. 1.Khusnutdinova, E.F., Smirnova, I.E., Kazakova, O.B., et al.Synthesis and evaluation of 2,3-indolotriterpenoids as new α-glucosidase inhibitorsMed. Chem. Res.262732-2742(2017)
T32140	Iguesterin Isoiguesterin	Others	Others
	Iguesterinn is a novel quinone triterpenoid from Catha Cassinoides with strong cell inhibitory activity.
TP2437	Sarasinoside A1 Sarasinoside-A1
	Sarasinoside A1 is a triterpenoid saponin that reverses mesenchymal tumor transformation.
T38088	28-Deoxybetulin methyleneamine	Others	Others
	28-Deoxybetulin methyleneamine is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It has been used in the synthesis of triterpene derivatives with antiviral activity. 1.Nitz, T.J., Montalbetti, C., Mears, R., et al.Extended Triterpene Derivatives(2008)
TP2439	Sarasinoside C1 Sarasinoside-C1
	Sarasinoside C1 is a norlanostane-triterpenoid oligoglycoside from the Palauan marine sponge Asteropus sarasinosum.
T33401	Missourin	Others	Others
	Missouri is a triterpenoid derived from the root of the Missouri iris. In addition, two known triterpenes, iso-iridogermanal, and zeorin, were isolated and identified.
T25357	Eburicone	Others	Others
	Eburicone 是一种羊毛甾烷型三萜类化合物，它可从香樟中分离得到，具有抗肿瘤活性。
T31903	Galphimine B	Others	Others
	Galphimine B is a cyclodesiccated triterpenoid from Galphimia Glauca, which can regulate the synaptic transmission of dopaminergic ventral tegmental neurons and has a sedative effect.
T85009	Betulinic glycine amide Betulinic glycine amide	Others	Others
	Betulinic glycine amide, a pentacyclic triterpenoid derivative of betulinic acid, serves as a precursor for synthesizing derivatives with anticancer and antiviral activity.
T25000	Acetylaleuritolic acid NSC 266221,NSC-266221,NSC266221	Others	Others
	Acetylaleuritolic acid 是一种从小花加西亚叶中分离得到的一种五环三萜类化合物，植物代谢产物。它具有抗肿瘤特性，对P-388淋巴细胞白血病测试中显示出肿瘤抑制活性。
T32287	Jegosapogenol A Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D	Others	Others
	Jegosapogenol A is a type of triterpenoid. Triterpenoids are terpene molecules containing six isoprene units. Barringtogenol C is a very weakly acidic compound (based on its pKa) and practically insoluble (in water). Barringtogenol C exists in tea. It can
T37782	2,3-Indolobetulonic Acid	Others	Others
	2,3-Indolobetulonic acid is pentacyclic triterpenoid derivative of betulonic acid and an inhibitor of α-glucosidase (IC50= 1.8 μM).1 1.Khusnutdinova, E.F., Smirnova, I.E., Kazakova, O.B., et al.Synthesis and evaluation of 2,3-indolotriterpenoids as new α-glucosidase inhibitorsMed. Chem. Res.262732-2742(2017)
T35693	N-(2-Azidoethyl)betulonamide	Others	Others
	N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1 1.Suman, P., Patel, A., Solano, L., et al.Synthesis and cytotoxicity of Baylis-Hillman template derived betulinic acid-triazole conjugatesTetrahedron73(29)4214-4226(2017)
T70029	Ibrexafungerp citrate	Others	Others
	Ibrexafungerp citrate is a triterpenoid antifungal. Similarly to echinocandins, it inhibits the synthesis of 1,3-β-d-glucan. However, it binds to a different site on the enzyme than echinocandins, resulting in limited cross-resistance. Ibrexafungerp exerts concentration-dependent fungicidal activity against Candida species and retains in vitro activity against most fluconazole-resistant strains.
T37039	Betulinic Aldehyde oxime	Others	Others
	Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It is active againstE. aerogenes,E. coli,E. faecalis,P. aeruginosa,S. aureus, andC. albicans, as well asL. donovaniamastigotes, when used at a concentration of 50 μM.1,2Betulinic aldehyde oxime (50 μM) is cytotoxic to Huh7 hepatocellular carcinoma cells.2
T74243	Tyrosinase/elastase-IN-1	Others	Others
	Tyrosinase/elastase-IN-1，一种来源于悬钩子叶的三萜类化合物，具有抑制酪氨酸酶和弹性蛋白酶活性的功能。
T36318	28-Acetylbetulin	Others	Others
	28-Acetylbetulin is a lupane triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found inM. chiapensisand has anti-inflammatory and anticancer activities.1,2It inhibits LPS-induced nitric oxide (NO) and prostaglandin E2production by 55.9 and 69.5%, respectively, in RAW 264.7 cells (IC50s = 4.7 and 1.7 μM, respectively).128-Acetylbetulin induces cytotoxicity in a variety of cancer cells, including A549, HT-29, and MCF-7 cells (IC50s = 14.37, 10.96, and 11.3...
T78887	ROS-IN-2	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	ROS-IN-2 (compound 85) 为次狼烷三萜衍生物，具有抑制细胞内过量ROS及其他氧化应激源生成的作用，从而保护线粒体避免受损。该化合物在心肌缺血/再灌注（MI/R）损伤研究中具有潜在应用价值。
T69244	Betulonaldehyde	Others	Others
	Betulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula. It is active against P. falciparum (IC50 = 3.36 µg/ml) and cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s = 19.23 and 17.09 µg/ml, respectively). Topical application of betulonaldehyde (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice. It has also been used a precursor in t...

化合物

Cat.No: T124663

Target: Immunology/Inflammation related

Cat.No: T6919

Synonym: RTA-408

Target: Apoptosis, Others, Nrf2, STING

Bardoxolone Methyl

Cat.No: T6165

Synonym: RTA 402,CDDO Methyl ester,TP-155,甲基巴多索隆,NSC 713200

Target: Apoptosis, IκB/IKK, Ferroptosis, Nrf2, Autophagy

Cat.No: T13604

Target: Others, NF-κB, Nrf2

Cat.No: T34516

Synonym: NSC 270047,NSC270047,NSC-270047

Target: Others

Cat.No: T34437

Target: Others

Cat.No: T26056

Target: Others

Justicisaponin I

Cat.No: T32325

Target: Others

Cat.No: T33627

Target: Others

Methyl adenophorate

Cat.No: T33335

Target: Others

Lantaiursolic acid

Cat.No: T32565

Target: Others

Sarasinoside B1

Cat.No: TP2438

Synonym: Sarasinoside-B1

Schisandronic acid

Cat.No: T34574

Synonym: Schizandronic acid,Ganwuweizic acid

Target: Others

Saniculoside R 1

Cat.No: TP2436

Synonym: Saniculoside R-1

Cat.No: T20613

Target: Others

Cat.No: T32203

Synonym: (+)-Isobauerenol

Target: Others

Cat.No: T32044

Target: Others

Lantanolic acid

Cat.No: T32566

Target: Others

2,3-Indolobetulin

Cat.No: T37781

Target: Others

Cat.No: T32140

Synonym: Isoiguesterin

Target: Others

Sarasinoside A1

Cat.No: TP2437

Synonym: Sarasinoside-A1

28-Deoxybetulin methyleneamine

Cat.No: T38088

Target: Others

Sarasinoside C1

Cat.No: TP2439

Synonym: Sarasinoside-C1

Cat.No: T33401

Target: Others

Cat.No: T25357

Target: Others

Cat.No: T31903

Target: Others

Betulinic glycine amide

Cat.No: T85009

Synonym: Betulinic glycine amide

Target: Others

Acetylaleuritolic acid

Cat.No: T25000

Synonym: NSC 266221,NSC-266221,NSC266221

Target: Others

Jegosapogenol A

Cat.No: T32287

Synonym: Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D

Target: Others

2,3-Indolobetulonic Acid

Cat.No: T37782

Target: Others

N-(2-Azidoethyl)betulonamide

Cat.No: T35693

Target: Others

Ibrexafungerp citrate

Cat.No: T70029

Target: Others

Betulinic Aldehyde oxime

Cat.No: T37039

Target: Others

Tyrosinase/elastase-IN-1

Cat.No: T74243

Target: Others

28-Acetylbetulin

Cat.No: T36318

Target: Others

Cat.No: T78887

Target: Reactive Oxygen Species

Betulonaldehyde

Cat.No: T69244

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2S0501	Ilexgenin A	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Ilexgenin A 是一种五环三萜类化合物，提取自海南冬青，可用于研究炎症及癌症。
T5783	Rosamultin 野蔷薇苷,罗莎白素	Antioxidant; HIV Protease	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Rosamultin 是从Potentilla anserina L 分离的 19 α-羟基型三萜。它抑制 HIV-1 蛋白酶，具有抗氧化、抗炎和镇痛作用。
T5S1133	Ganoderic acid D 灵芝酸D,灵芝酸 D	Apoptosis; Sirtuin	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Ganoderic acid D 是高度氧化的四环三萜，是灵芝的主要活性成分，可诱导 HeLa 人宫颈癌细胞凋亡。它上调 SIRT3的蛋白质表达并通过 SIRT3 诱导脱乙酰化的亲环蛋白 D 。它抑制结肠癌细胞的能量重编程，包括结肠癌细胞中的葡萄糖摄取，乳酸、丙酮酸和乙酰辅酶的产生。
TN6722	Terminolic acid 2α,6β,23-trihydroxyl oleanolic acid	Antibacterial	Microbiology/Virology
	Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) 是一种从 Combretum racemosum 中分离得到的五环三萜糖苷，可通过与 IL-1β 和 IL-6 的受体活性位点结合抑制促炎细胞因子，并通过与 IL-4 受体结合位点结合增强抗炎细胞因子。它还表现出适度的抗菌活性。
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸	NOS; NO Synthase; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞，减少NO 产生和 iNOS 表达，具有消炎作用。
TN2450	Acetyl 11α-methoxy-β-boswellic Acid	Others	Others
	Acetyl 11α-methoxy-β-boswellic Acid是从乳香树脂中提取到的三萜类化合物。
T4S1387	Isoescin IA 七叶皂苷C,异七叶皂苷 IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Isoescin IA 是一种从七叶树种子中分离出来的三萜皂苷。它具有抗HIV-1蛋白酶活性。
T13640	Dehydroeburicoic acid monoacetate 3-O-Acetyldehydroeburicoic acid,去氢齿孔酸乙酰酯	Others	Others
	Dehydroeburicoic acid monoacetate (3-O-Acetyldehydroeburicoic acid) 是一种羊毛脂烷型三萜类化合物，来源于茯苓。
TN2337	Poricoic acid AM
	Poricoic acid AM 是一种从茯苓中提取的三萜类化合物，具有抗肿瘤活性。
T0722	Ursolic acid Malol,熊果酸,Urson,NSC 167406,NSC-4060,Prunol	Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Ursolic acid (Prunol) 是从毛喉杜鹃中提取的一种五环三萜羧酸，具有预防和抗癌活性。
TCS1188	Mogroside III	Others	Others
	Mogroside III 是一种三萜糖苷和非糖甜味剂。 Mogroside III 被人体肠道细菌转化，释放出次生Mogroside IIA1 和苷元莫格罗。
T2728	Limonin Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,柠檬苦素,Obaculactone,Citrolimonin	Apoptosis; HIV Protease; Endogenous Metabolite	Apoptosis; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Limonin (Citrolimonin) 是柑橘类水果中富含的一种三萜类天然产物，具有抗病毒和抗肿瘤活性。
T4S1848	Tubeimoside II Tubeimoside-B,土贝母苷乙	Others	Others
	Tubeimoside II (Tubeimoside-B) 是一种齐墩果烷型三萜皂甙天然类似物，具有抗炎症和抗癌等生物特性。
T3S2197	Polygalic acid Senegenic acid,远志皂甙	Others	Others
	Polygalic acid (Senegenic acid) 是一种三萜皂苷，是远志 (Polygala tenuifolia) 的一种主要活性成分。
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester Hederagenin-28-beta-D-glucopyranoside,常春苷元-28-BETA-D-吡喃葡萄糖苷,常春藤皂苷元28-O-beta-D-吡喃葡萄糖酯	Others	Others
	Hederagenin-28-beta-D-glucopyranoside 是一种分离自Ilex cornuta中的三萜皂苷，能够保护H2O2诱导的心肌细胞免于损伤。
T5775	Cauloside F 红毛七皂苷F,红毛七皂苷 F	Others	Others
	Cauloside F 是一种三萜皂苷类化合物，分离自铁线莲中。
T8300	Mogroside IV-E mogroside Ive,罗汉果甙 IV	Antioxidant	oxidation-reduction
	Mogroside IV-E 是一种非糖类甜味剂，是一种三萜糖苷。Mogroside 比蔗糖更甜，具有抗氧化，抗糖尿病和抗癌作用。
TN1866	Licoricesaponin G2 甘草皂苷G2
	Licoricesaponin G2 是一种从 Glycyrrhiza aspera 中提取出的五环三萜类化合物，可用于区分粗甘草和蜂蜜加工甘草。
T2S1193	Mogroside III-A1 罗汉果苷 III-A1	Others	Others
	Mogroside III-A1 是一种来自罗汉果 Swingle 的三萜糖苷。 Mogroside III-A1 一种无糖甜味剂。
T3039	Hederagenin Hederagenic acid,常春藤苷元,Astrantiagenin E,Caulosapogenin,常春藤皂苷元,Hederagenol	Others	Others
	Hederagenin (Hederagenol) 是一种三萜皂苷，可以抑制细胞中由于LPS 刺激引起的 iNOS、COX-2和 NF-κB 的表达。
TN7059	Deoxylimonin NSC 314317,脱氧柠檬苦素,desoxylimonin	Others	Others
	Deoxylimonin (NSC 314317) 是一种分离自葡萄柚籽中的三萜化合物。它是一种母体衍生物，其抗癌、缓解疼痛和抗炎活性比母体化合物强。
TN7039	Celosin H	Others	Others
	Celosin H 是一种新型的保肝三萜皂苷，从 Celosiae Semen 的甲醇提取物中分离出来。
T3910	Pulchinenoside C Anemoside B4,Chinensioside A,Pulchinenoside B4,白头翁皂苷 B4,Pulsatilla saponin B4	IL Receptor	Immunology/Inflammation
	Pulchinenoside C (Anemoside B4) 是一种从 P. chinensis 中分离出来的丰富的三萜皂苷，具有抗炎和抗氧化作用。
T2741	Glycyrrhizic acid Glycyrrhizin,甘草酸	Virus Protease; Dehydrogenase; MAO	Metabolism; Microbiology/Virology; Neuroscience
	Glycyrrhizic acid (Glycyrrhizin) 是甘草里面的活性成分三萜皂苷，为 HMGB1的拮抗剂，有用于肿瘤、糖尿病等研究的潜力。
TN7060	Methyl oleanonate	PPAR	DNA Damage/DNA Repair; Metabolism
	Methyl oleanonate 是从柃木中分离得到的一种三萜类天然产物，是齐墩果酸衍生物，是一种PPARγ激动剂，具有抗癌作用。
T12090	Mogroside I E1 罗汉果苷 I E1	Others	Others
	Mogroside I E1 是三萜糖苷，是非糖类甜味剂。其中 Mogroside 的甜度比蔗糖高，具有抗氧化，抗糖尿病和抗癌特性。
T19882	Bryonolic acid UNII-J7YR6A878I,20-epi-Bryonolic acid	Apoptosis; Antioxidant; Calcium Channel	Apoptosis; Membrane transporter/Ion channel; Metabolism; oxidation-reduction
	Bryonolic acid (20-epi-Bryonolic acid) 是一种从 Sandoricum indicum 提取的三萜类化合物，具有免疫调节、抗炎，抗氧化和抗癌等活性，通过抑制Ca2+内流和调节Ca2+-CaMKII-CREB信号通路中的基因表达来避免PC12细胞免受NMDA诱导的细胞凋亡反应。
T3368	Alpha-Hederin α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C	Apoptosis; Others	Apoptosis; Others
	Alpha-Hederin (Tauroside E) 是存在于黑种草种子中的一种单桥糖三萜皂苷，具有抗肿瘤作用。它可通过激活线粒体依赖性途径抑制胃癌细胞增殖，诱导凋亡，并有活性氧生成和谷胱甘肽减少。
TN1553	Deacetyl ganoderic acid F	Others	Others
	Deacetyl ganoderic acid F (DeGA F) 是从灵芝 Ganoderma lucidum 中提取的三萜类化合物，在体外和体内对脂多糖（LPS）诱导的炎症有抑制作用。
T3387	Phytolaccagenin	Others; Antibacterial	Microbiology/Virology; Others
	Phytolaccagenin 是一种三萜类皂苷，是商陆的活性成分，有抗真菌活性，抗炎活性和较低的毒性。在东亚国家广泛用于治疗炎症相关疾病。
T5575	Cycloastragenol 环黄芪醇,Cyclogalegenol,Astramembrangenin	Epigenetic Reader Domain; Telomerase	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Cycloastragenol (Astramembrangenin) 是一种三萜皂苷类化合物，是黄芪主要活性成分的水解产物，具有抗氧化、抗炎、抗衰老、抗凋亡和心血管保护作用。它是端粒酶激活剂，可以延长端粒，还能缓解与年龄相关的骨丢失，改善骨微结构和生物力学特性。
TN1512	Clinopodiside A	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Clinopodiside A 是一种从 Clinopodium polycephalum 中分离出来的三萜皂苷，具有抗肿瘤活性，通过 T24 膀胱癌细胞中 BLK 和 RasGRP2 信号传导介导的自噬诱导细胞毒性。
T3918	Ginsenoside Rb3 人参皂苷 Rb3,Gypenoside IV,人参皂苷Rb3	NF-κB; COX; NO Synthase	Immunology/Inflammation; Neuroscience; NF-κB
	Ginsenoside Rb3 (Gypenoside IV) 是从三七中提取的一种天然产物。它在 293T 细胞系中抑制 TNFα 诱导的NF-κB 转录活性，IC50为 8.2 μM。它还抑制COX-2和iNOSmRNA 的诱导。
T4970	LANOSTEROL 羊毛甾醇,3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol	Endogenous Metabolite	Metabolism
	Lanosterol (3β-Hydroxy-8,24-lanostadiene) 是胆固醇合成的中间产物，能够诱导胆固醇合成的速率控制酶 HMG-CoA 还原酶的泛素化和降解。Lanosterol 可以抑制神经退行性疾病相关错误折叠蛋白的聚集和细胞毒性。
T8846	beta-Escin B-escin,AESCINE,beta-七叶素	Immunology/Inflammation related	Immunology/Inflammation
	beta-Escin 是七叶树种子的主要活性成分。它可抑制碱性成纤维细胞生长因子所诱导的增殖、迁移、管形成以及体内 CAM 血管生成。它具有研究抗血管生成作用的分子机制的潜力。
T3248	alpha-Boswellic acid α-Boswellic acid,α-乳香酸	Others	Others
	alpha-Boswellic acid 是一种从乳香中提取得到的五环三萜类化合物，具有抗惊厥和抗癌作用。在动物体内，它是预防和减少阿尔茨海默病标志物，可用于阿尔茨海默病的研究。
TN1219	20-Hydroxyganoderic acid G
	20-Hydroxyganoderic acid G 是从灵芝 (Ganoderma curtisii) 子实体乙醇提取物中获得的羊毛甾烷三萜类化合物。20-Hydroxyganoderic Acid G 对由 LPS 激活的 BV-2 小胶质细胞有抑制作用，IC50 值为 21.33 μM。20-Hydroxyganoderic Acid G 用于研究由LPS 激活的小胶质细胞相关的神经炎症疾病。
T2915	Bardoxolone RTA 401,齐墩果烷三萜化合物,CDDO	Others; Nrf2	Immunology/Inflammation; Others
	Bardoxolone (CDDO) 是新型核调节因子激活剂。
TN1831	Macranthoside A Kalopanaxsaponin H	Antioxidant	oxidation-reduction
	Macranthoside A (Kalopanaxsaponin H) 是一种从地黄中提取的三萜糖苷，属于环烯醚萜类化合。Macranthoside A 具有抗炎、抗氧化、抗菌和神经保护活性，抑制促炎细胞因子的产生和抑制炎症信号通路的激活，有助于中和有害的自由基，保护细胞免受氧化损伤，可以促进神经元的存活和生长，并防止氧化应激或神经毒性化合物引起的神经元细胞死亡，具有治疗神经退行性疾病、心血管疾病和肝损伤的潜力。
TN1013	Cucurbitacin D	Apoptosis	Apoptosis
	Cucurbitacin D 是一种从 Ecballium elaterium （L.）分离出来的三萜类化合物，具有抗癌抗肿瘤活性，抑制转移性 PrC 中的葡萄糖摄取和乳酸产生，诱导独立于 ERK1/2 激活的炎症小体激活。 Cucurbitacin D 是巨噬细胞中的一种新的炎症小体激活剂，通过调节 JAK/STAT3、PI3K/Akt/mTOR 和 MAPK 信号通路抑制 HepG2 细胞增殖并诱导细胞凋亡，可用于研究宫颈癌、白血病和前列腺癌。
TN1056	Mogroside IIe	IL Receptor	Immunology/Inflammation
	Mogroside IIe 是一种天然来源的三萜糖苷，作为非糖类甜味剂，Mogroside 比蔗糖更甜。Mogroside 具有抗氧化，抗糖尿病和抗癌活性。
TN2446	3-Oxobetulin Betulone	Antiviral	Immunology/Inflammation
	Betulone is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane.
T39245	Poricoic acid BM	Others	Others
	Poricoic acid BM is a lanostane triterpenoid present in the peels of Wolfiporia cocos mushrooms.
T23825	Bryononic acid
	Bryononic acid is a new cucurbitane-type triterpenoid. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
T40672	Bacoside A2 假马齿苋素A2	Others	Others
	Bacoside A2 is a triterpenoid saponin.
T31912	Ganolucidic acid D (+)-Ganolucidic acid D
	Ganolucidic acid D, also known as ganolucidate D, is a triterpenoid.
T39385	15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid	Others	Others
	15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid is a Lanostane triterpenoid compound with the ability to inhibit NO production in LPS-induced microglia.
T26055	Regelin Regelin C
	Regelin is an antitumor ursene-type triterpenoid isolated from Tripterygium regelii.
T83206	Acanthopanaxoside A
	Acanthopanaxoside A 为三萜类皂苷化合物，能够抑制胰腺脂肪酶 (lipase) 活性。
T82825	Brachyoside B
	Brachyoside B，一种三萜皂苷，源自Astragalus wiedemannianus。
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天然产物

Cat.No: T2S0501

Target: IL Receptor, TNF

Cat.No: T5783

Synonym: 野蔷薇苷,罗莎白素

Target: Antioxidant, HIV Protease

Ganoderic acid D

Cat.No: T5S1133

Synonym: 灵芝酸D,灵芝酸 D

Target: Apoptosis, Sirtuin

Terminolic acid

Cat.No: TN6722

Synonym: 2α,6β,23-trihydroxyl oleanolic acid

Target: Antibacterial

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid

Cat.No: TN1109

Synonym: 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸

Target: NOS, NO Synthase, Prostaglandin Receptor

Acetyl 11α-methoxy-β-boswellic Acid

Cat.No: TN2450

Target: Others

Cat.No: T4S1387

Synonym: 七叶皂苷C,异七叶皂苷 IA

Target: HIV Protease

Dehydroeburicoic acid monoacetate

Cat.No: T13640

Synonym: 3-O-Acetyldehydroeburicoic acid,去氢齿孔酸乙酰酯

Target: Others

Poricoic acid AM

Cat.No: TN2337

Cat.No: T0722

Synonym: Malol,熊果酸,Urson,NSC 167406,NSC-4060,Prunol

Target: Endogenous Metabolite, Autophagy

Cat.No: TCS1188

Target: Others

Cat.No: T2728

Synonym: Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,柠檬苦素,Obaculactone,Citrolimonin

Target: Apoptosis, HIV Protease, Endogenous Metabolite

Cat.No: T4S1848

Synonym: Tubeimoside-B,土贝母苷乙

Target: Others

Cat.No: T3S2197

Synonym: Senegenic acid,远志皂甙

Target: Others

Hederagenin 28-O-beta-D-glucopyranosyl ester

Cat.No: T3S0208

Synonym: Hederagenin-28-beta-D-glucopyranoside,常春苷元-28-BETA-D-吡喃葡萄糖苷,常春藤皂苷元28-O-beta-D-吡喃葡萄糖酯

Target: Others

Cat.No: T5775

Synonym: 红毛七皂苷F,红毛七皂苷 F

Target: Others

Cat.No: T8300

Synonym: mogroside Ive,罗汉果甙 IV

Target: Antioxidant

Licoricesaponin G2

Cat.No: TN1866

Synonym: 甘草皂苷G2

Mogroside III-A1

Cat.No: T2S1193

Synonym: 罗汉果苷 III-A1

Target: Others

Cat.No: T3039

Synonym: Hederagenic acid,常春藤苷元,Astrantiagenin E,Caulosapogenin,常春藤皂苷元,Hederagenol

Target: Others

Cat.No: TN7059

Synonym: NSC 314317,脱氧柠檬苦素,desoxylimonin

Target: Others

Cat.No: TN7039

Target: Others

Pulchinenoside C

Cat.No: T3910

Synonym: Anemoside B4,Chinensioside A,Pulchinenoside B4,白头翁皂苷 B4,Pulsatilla saponin B4

Target: IL Receptor

Glycyrrhizic acid

Cat.No: T2741

Synonym: Glycyrrhizin,甘草酸

Target: Virus Protease, Dehydrogenase, MAO

Methyl oleanonate

Cat.No: TN7060

Target: PPAR

Cat.No: T12090

Synonym: 罗汉果苷 I E1

Target: Others

Cat.No: T19882

Synonym: UNII-J7YR6A878I,20-epi-Bryonolic acid

Target: Apoptosis, Antioxidant, Calcium Channel

Cat.No: T3368

Synonym: α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C

Target: Apoptosis, Others

Deacetyl ganoderic acid F

Cat.No: TN1553

Target: Others

Phytolaccagenin

Cat.No: T3387

Target: Others, Antibacterial

Cycloastragenol

Cat.No: T5575

Synonym: 环黄芪醇,Cyclogalegenol,Astramembrangenin

Target: Epigenetic Reader Domain, Telomerase

Clinopodiside A

Cat.No: TN1512

Target: DNA/RNA Synthesis

Ginsenoside Rb3

Cat.No: T3918

Synonym: 人参皂苷 Rb3,Gypenoside IV,人参皂苷Rb3

Target: NF-κB, COX, NO Synthase

Cat.No: T4970

Synonym: 羊毛甾醇,3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol

Target: Endogenous Metabolite

Cat.No: T8846

Synonym: B-escin,AESCINE,beta-七叶素

Target: Immunology/Inflammation related

alpha-Boswellic acid

Cat.No: T3248

Synonym: α-Boswellic acid,α-乳香酸

Target: Others

20-Hydroxyganoderic acid G

Cat.No: TN1219

Cat.No: T2915

Synonym: RTA 401,齐墩果烷三萜化合物,CDDO

Target: Others, Nrf2

Macranthoside A

Cat.No: TN1831

Synonym: Kalopanaxsaponin H

Target: Antioxidant

Cat.No: TN1013

Target: Apoptosis

Cat.No: TN1056

Target: IL Receptor

Cat.No: TN2446

Synonym: Betulone

Target: Antiviral

Poricoic acid BM

Cat.No: T39245

Target: Others

Cat.No: T23825

Cat.No: T40672

Synonym: 假马齿苋素A2

Target: Others

Ganolucidic acid D

Cat.No: T31912

Synonym: (+)-Ganolucidic acid D

15a-Hydroxy-3,11,23-trioxo-lanost-8,20-dien-26-oic acid

Cat.No: T39385

Target: Others

Cat.No: T26055

Synonym: Regelin C

Acanthopanaxoside A

Cat.No: T83206

Cat.No: T82825

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Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0205	Glycyrrhetinic acid-d3
	Glycyrrhetinic acid-d3 是 Glycyrrhetinic acid 的氘代化合物。Glycyrrhetinic acid 的 CAS 号为 1449-05-4。Glycyrrhetinic acid是一种饮食衍生的化合物，是NF-kB的抑制剂和蛋白酶体的激活剂，在多细胞生物中起到促进长寿和抗聚集因子的作用。它诱导细胞凋亡。

同位素标记化合物

Glycyrrhetinic acid-d3

Cat.No: TMIJ-0205

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